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Septal defects

EFO Endpoint Browser PheWeb

Q17_SEPTA_DEFEC

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q21.0, Q21.10, Q21.11, Q21.12, Q21.13, Q21.18, Q21.19, Q21.88, Q21.9
  • Hospital discharge: ICD-9 — 7454E|7454X|7454A|7455A|7456X|7456A|7458X|7459X
  • Hospital discharge: excluded ICD-10 — Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Hospital discharge: excluded ICD-9 — 758|7595|75683
  • Cause of death: ICD-10 — Q21.0, Q21.10, Q21.11, Q21.12, Q21.13, Q21.18, Q21.19, Q21.88, Q21.9
  • Cause of death: ICD-9 — 7454E|7454X|7454A|7455A|7456X|7456A|7458X|7459X
  • Cause of death: excluded ICD-10 — Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Cause of death: excluded ICD-9 — 758|7595|75683

2 out of 7 registries used, show all original rules.

2827

4. Check minimum number of events

None

2827

5. Include endpoints

None

2827

6. Filter based on genotype QC (FinnGen only)

2555

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF7

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 37758 20128 17561
Only index persons 24425 13039 11386
Unadjusted period prevalence (%)
Whole population 0.54 0.58 0.49
Only index persons 0.46 0.48 0.43
Median age at first event (years)
Whole population 0.53 0.50 0.42
Only index persons 3.90 4.73 2.96

-FinnGen-

Key figures

All Female Male
Number of individuals 2555 1532 1023
Unadjusted period prevalence (%) 0.51 0.54 0.47
Median age at first event (years) 41.00 37.80 45.77

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2663
Matched controls
26071
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
15.8
317.7
287
198
Q21.10
ICD-10 Finland
Persistent ostium secundum
11763.9
307.7
843
*
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
+∞
307.7
531
*
B01AA03
ATC
warfarin; systemic
5.8
307.7
738
1617
XF620
NOMESCO Finland
Examination of circulation with color method
135.8
307.7
274
22
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
307.7
342
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
6.8
307.7
1017
2161
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
567.5
307.7
354
7
Q21.19
ICD-10 Finland
Atrial septal defect NOS
5133.8
307.7
450
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
12.0
307.7
379
355
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
307.7
373
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
28.2
307.7
1065
602
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
12344.6
307.7
871
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
6.5
307.7
1312
3390
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
7.2
297.4
504
822
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
8.3
293.1
427
588
31
HP
Congenital heart failure surgery
113.7
274.5
143
13
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
27.8
256.4
178
67
201
Kela drug reimbursment
Chronic cardiac insufficiency
8.8
239.4
322
400
XF400
NOMESCO Finland
ECG with 12 standard connections
4.2
220.9
763
2279
XF404
NOMESCO Finland
Ambulatory ECG
5.3
197.6
450
959
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
5.1
184.7
445
993
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
+∞
183.1
175
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
180.0
1524
7797
FM2CE, ,
NOMESCO Finland
7.1
136.5
217
323
62
HP
Catheterization and pressure measurement of the right side of the heart
52.4
133.7
78
15
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
10.1
131.1
153
156
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.5
131.1
555
1844
FFC42
NOMESCO Finland
Percutaneous closure of patent foramen ovale
+∞
127.1
122
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
6.1
125.9
233
405
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
+∞
124.0
119
*
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
+∞
121.9
117
*
C01AA05
ATC
digoxin; systemic
5.5
121.8
250
479
Q21.0
ICD-10 Finland
Ventricular septal defect
318.2
121.3
123
*
Q25.1
ICD-10 Finland
Coarctation of aorta
23.4
119.8
88
38
Q25.0
ICD-10 Finland
Patent ductus arteriosus
15.5
117.3
104
68
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.1
115.1
610
2304
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.2
113.0
332
854
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
213.9
101.4
105
5
5253
FHL
Cardiac lung machine
25.5
99.9
71
28
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
5.9
98.5
185
325
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
36.5
97.6
62
17
TFP20
NOMESCO Finland
Cardiodefibrillation
4.5
97.1
256
604
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
+∞
95.7
92
*
C03CA01
ATC
furosemide; systemic
2.7
95.6
689
3031
61
HP
Catheterization and pressure measurement of the left side of the heart
12.1
94.9
97
81
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
93.3
418
1418
TPX22
NOMESCO Finland
Intravenous arterial thrombolysis
18.6
91.5
74
40
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.7
88.3
569
2357
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
11.5
87.8
93
82
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
33.5
87.6
57
17
B01AC04
ATC
clopidogrel; oral
3.1
87.5
428
1526
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
86.7
882
4522
XFE00
NOMESCO Finland
Epicardial ultrasonography
8.4
85.8
115
140
Q23.11
ICD-10 Finland
Bicuspid aortic valve
10.2
83.8
96
95
AA1AD
NOMESCO Finland
CT of head and brain
2.4
83.0
771
3787
WX872
NOMESCO Finland
Intensive care
4.8
82.7
198
431
XF402
NOMESCO Finland
ECG with work load test
3.4
81.3
331
1055
XF622
NOMESCO Finland
Measurement of minute volume of heart
22.2
80.2
60
27
PA2AE
NOMESCO Finland
Ultrasound examination of brain artery
122.8
78.7
85
7
XA800
NOMESCO Finland
Neuropsychological investigation
3.6
77.2
279
823
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
4.3
76.7
213
521
5205
FHL
ASD blockage, secondary defect
+∞
75.8
73
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.9
75.5
241
653
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
194.0
73.9
77
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.0
70.9
342
1202
I50.9
ICD-10 Finland
Heart failure, unspecified
3.2
70.7
316
1063
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
12.8
70.1
69
54
R4150
NOMESCO Finland
Neuropsychological rehabilitation
10.6
69.2
77
73
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
6.8
69.1
110
163
C03DA01
ATC
spironolactone; oral
3.0
68.5
348
1259
207
Kela drug reimbursment
Chronic arrhythmias
2.9
67.8
373
1409
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
4.5
67.5
170
385
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
67.5
65
*
WX892
NOMESCO Finland
Monitored bed care
3.2
67.4
295
979
I34.1
ICD-10 Finland
Mitral (valve) prolapse
6.1
64.6
115
191
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
14.0
64.1
60
43
XF640, ,
NOMESCO Finland
6.2
61.8
108
176
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
61.8
971
5753
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
4.3
61.2
167
402
C07AB07
ATC
bisoprolol; oral
2.0
61.1
1062
6514
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
60.8
1057
6482
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
60.5
686
3593
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
4.3
60.3
165
398
K78
ICPC
Atrial fibrillation/flutter
3.6
58.6
202
575
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
12.3
58.5
59
48
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
5.2
58.5
123
239
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
58.1
56
*
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
5.0
57.8
129
264
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.2
57.3
245
799
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
6.7
57.1
93
141
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
56.8
415
1797
Q21.1
ICD-10 Finland
Atrial septal defect
+∞
55.0
53
*
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
6.9
53.3
84
123
FFC50
NOMESCO Finland
Closure of ostium secundum type ASD using patch
+∞
52.9
51
*
XF600
NOMESCO Finland
Bloodpressure measurement
2.8
52.8
287
1071
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.5
52.1
194
580
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
16.7
49.4
42
25
Q21.20
ICD-10 Finland
Atrial septal defect of primum type
486.5
49.1
49
*
APK
HP
ASD closure
+∞
48.7
47
*
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
13.0
48.3
47
36
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.5
48.1
345
1475
I63
ICD-10 Finland
Cerebral infarction
12.6
47.5
47
37
I50.0
ICD-10 Finland
Congestive heart failure
3.6
46.9
165
475
5207
FHL
VSD closure
+∞
45.6
44
*
Q21.30
ICD-10 Finland
Tetralogy of Fallot
15.3
45.0
40
26
K90
ICPC
Stroke/cerebrovascular accident
5.0
44.8
98
197
APJ
HP
PFO closure
+∞
44.6
43
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
44.1
657
3744
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.4
43.8
343
1523
AF1
HP
Surgery of congenital heart defect
224.0
43.7
45
*
Q21.12
ICD-10 Finland
Defective sinus venosus
+∞
43.5
42
*
C01BD01
ATC
amiodarone; systemic
5.1
43.3
93
184
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
149.3
42.5
45
*
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.9
41.9
129
339
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
6.4
41.5
70
110
ZXE00
NOMESCO Finland
One hour or less
1.8
41.4
1065
7162
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
3.1
41.2
184
614
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
4.7
40.2
94
200
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.4
40.1
301
1309
WX402
NOMESCO Finland
General anaesthesia
1.9
39.8
710
4270
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
4.5
39.7
100
226
Z2221
NOMESCO Finland
Medical doctor
1.8
39.5
763
4700
I49.5
ICD-10 Finland
Sick sinus syndrome
4.3
39.1
103
241
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
15.1
39.1
35
23
AA5PD
NOMESCO Finland
CT examination of brain pefusion
8.5
39.0
51
60
WX882
NOMESCO Finland
High dependency care
2.9
38.0
192
686
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
37.9
590
3389
C07AA07
ATC
sotalol; systemic
4.4
37.9
97
222
B01AB05
ATC
enoxaparin; parenteral
1.8
37.7
689
4164
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
37.6
381
1878
R4110
NOMESCO Finland
Physiotherapy
1.8
37.2
763
4771
I48.4
ICD-10 Finland
Atypical atrial flutter
12.2
36.7
37
30
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
14.9
36.5
33
22
7456A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[DEFECTUS SEPTI ATRIORUM NUD]
+∞
36.2
35
*
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
5.3
35.8
73
138
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
14.2
35.7
33
23
Q21.21
ICD-10 Finland
Atrioventricular duct
79.6
35.6
40
5
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
3.9
34.7
106
277
Q20.1
ICD-10 Finland
Double outlet right ventricle
94.4
34.5
38
*
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
9.5
34.2
41
43
B01AF02
ATC
apixaban; oral
2.3
32.9
275
1250
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
9.0
32.2
40
44
R4120
NOMESCO Finland
Occupational therapy
2.4
31.9
234
1004
ZXD05
NOMESCO Finland
Urgent procedure
1.7
30.3
745
4853
C10AA05
ATC
atorvastatin; oral
1.7
30.1
802
5335
K84
ICPC
Heart disease other
4.2
30.1
82
197
Q21.29
ICD-10 Finland
Atrioventricular septal defect UNS
+∞
30.0
29
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
29.5
439
2465
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.6
28.8
98
276
I44.2
ICD-10 Finland
Atrioventricular block, complete
4.2
28.7
78
187
R06.0
ICD-10 Finland
Dyspnoea
1.7
28.6
633
4000
I48.2
ICD-10 Finland
Chronic atrial fibrillation
3.3
27.5
108
333
I35.0
ICD-10 Finland
Aortic (valve) stenosis
3.0
27.4
124
416
G04BE03
ATC
sildenafil; oral
5.2
27.1
56
107
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
7.0
26.8
41
58
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
61.4
26.7
31
5
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
40.8
26.5
33
8
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
95.7
26.4
29
*
TFP34
NOMESCO Finland
Electrophysiological investigation
3.3
26.2
100
303
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
6.5
25.7
42
64
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
25.6
266
1314
RS224, ,
NOMESCO Finland
5.4
25.3
50
92
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
6.0
25.2
45
75
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
4.3
25.2
65
150
PD5BD
NOMESCO Finland
Extensive CT of aorta
5.7
25.1
47
82
C09AA05
ATC
ramipril; oral
1.8
25.0
450
2670
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.1
24.9
261
1294
Q26.1
ICD-10 Finland
Persistent left superior vena cava
57.4
24.8
29
5
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.0
24.7
109
361
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
38.4
24.6
31
8
Q26.3
ICD-10 Finland
Partial anomalous pulmonary venous connection
89.0
24.5
27
*
I37.0
ICD-10 Finland
Pulmonary valve stenosis
42.4
24.3
30
7
XX3BT
NOMESCO Finland
Other labeling with X-ray guidance
5.0
24.2
52
103
R04.0
ICD-10 Finland
Epistaxis
2.3
23.8
189
838
Z3231
NOMESCO Finland
Registered nurse
1.6
23.6
760
5241
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.9
23.2
320
1745
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
6.0
23.1
41
68
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
23.0
611
4019
I48.1
ICD-10 Finland
Persistent atrial fibrillation
3.1
22.9
95
303
C07AB02
ATC
metoprolol; systemic
1.8
22.8
367
2101
H53.4
ICD-10 Finland
Visual field defects
3.9
22.8
68
175
Z31.5
ICD-10 Finland
Genetic counselling
2.2
22.5
206
968
AP2
HP
Catheterization of the right side of the heart
22.6
22.3
32
14
250, ,
Kela drug reimbursment
4.4
22.0
55
124
Q90.9
ICD-10 Finland
Down syndrome, unspecified
51.4
21.9
26
5
PA6AD
NOMESCO Finland
CT of neck arteries
2.9
21.7
107
377
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
8.2
21.7
29
35
R42
ICD-10 Finland
Dizziness and giddiness
1.7
21.5
507
3228
74646
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium primum
217.1
21.4
22
*
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
42.8
21.2
26
6
602
Kela drug reimbursment
Children's severe malnutrition
3.5
20.8
73
210
I47.1
ICD-10 Finland
Supraventricular tachycardia
2.6
20.8
128
506
R01.1
ICD-10 Finland
Cardiac murmur, unspecified
2.9
20.3
99
347
WW502
NOMESCO Finland
Autotransfusion
8.6
20.1
26
30
I42.0
ICD-10 Finland
Dilated cardiomyopathy
3.6
20.0
65
178
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
19.9
410
2515
Z98.8
ICD-10 Finland
Other specified postsurgical states
4.1
19.9
55
134
Q20.48
ICD-10 Finland
Single ventricle
26.7
19.8
27
10
AP3
HP
Catheterization of the right and left side of the heart
23.1
19.7
28
12
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
20.5
19.7
29
14
J01CA04
ATC
amoxicillin; systemic
1.7
19.7
2262
20101
FFC32
NOMESCO Finland
Percutaneous transluminal closure of sinus venosus type ASD
+∞
19.7
19
*
90492, ,
NOMESCO Finland
72.5
19.5
22
*
FFC40
NOMESCO Finland
Closure of Patent Foramen Ovale
197.2
19.4
20
*
Q21.80
ICD-10 Finland
Communication from left ventricle to right atrium
197.2
19.4
20
*
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.2
19.1
173
809
UGC02
NOMESCO Finland
Rigid bronchoscopy
5.9
18.9
34
57
K83
ICPC
Heart valve disease NOS
5.6
18.9
36
64
I50.1
ICD-10 Finland
Left ventricular failure
2.8
18.8
93
329
TFP35
NOMESCO Finland
Electroanatomical mapping
4.2
18.6
49
115
AN1
HP
Coronary angiography
2.1
18.5
183
886
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.7
18.5
101
376
342
Kela drug reimbursment
Dronedarone
6.7
18.2
29
43
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
17.8
252
1383
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
51.8
17.8
21
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.0
17.6
78
259
R62.0
ICD-10 Finland
Delayed milestone
2.8
17.6
91
329
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
6.0
17.6
31
51
7454X
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[VSD ALIA DEFINITA]
+∞
17.6
17
*
FFC96
NOMESCO Finland
Other closure of isolated atrial septal defect
+∞
17.6
17
*
Q21.88
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
17.6
17
*
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
6.2
17.5
30
48
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
28.4
17.2
23
8
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.1
16.9
69
219
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
16.8
541
3688
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
3.7
16.7
52
138
WX704
NOMESCO Finland
Intubation
2.0
16.7
202
1051
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
62.4
16.6
19
*
81
HP
Angiography of the heart and coronary arteries
2.6
16.6
95
363
H53.0
ICD-10 Finland
Amblyopia ex anopsia
3.4
16.4
60
178
Z3226
NOMESCO Finland
Physiotherapist
1.6
16.4
481
3212
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
5.7
16.2
30
52
I47.2
ICD-10 Finland
Ventricular tachycardia
3.6
16.0
53
147
Q87.14
ICD-10 Finland
Noonan's syndrome
29.6
15.9
21
7
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
12.6
15.9
28
22
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
3.7
15.6
49
131
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.8
15.6
76
267
7470A
ICD-9 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
32.9
15.6
20
6
R4130
NOMESCO Finland
Speech therapy
2.4
15.6
107
446
Q21.8
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
15.5
15
*
Q21.81
ICD-10 Finland
Eisenmenger's syndrome
+∞
15.5
15
*
51
HP
Other heart surgery
83.8
15.4
17
*
R47.0
ICD-10 Finland
Dysphasia and aphasia
5.3
15.4
31
58
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
3.8
15.4
46
119
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
18.9
15.4
23
12
FHB00
NOMESCO Finland
Transatrial suture of VSD
157.5
15.4
16
*
C01BD07
ATC
dronedarone; oral
6.8
15.3
24
35
Q22.0
ICD-10 Finland
Pulmonary valve atresia
37.5
15.2
19
5
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
5.5
15.1
29
52
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
15.8
15.0
24
15
F83
ICD-10 Finland
Mixed specific developmental disorders
2.7
15.0
79
289
K80
ICPC
Cardiac arrhythmia NOS
1.9
14.9
190
1008
FM1CD
NOMESCO Finland
Very extensive CT of heart
13.7
14.8
25
18
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
31.2
14.6
19
6
I27.0
ICD-10 Finland
Primary pulmonary hypertension
18.1
14.5
22
12
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
14.5
196
1059
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
3.3
14.5
55
167
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
14.5
14
*
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
5.1
14.4
30
58
Q20.40
ICD-10 Finland
Double inlet left ventricle
147.6
14.3
15
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
14.3
1100
8789
C01BC04
ATC
flecainide; systemic
2.7
14.3
76
280
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.1
14.2
39
95
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.3
14.2
106
459
Q25.40
ICD-10 Finland
Aortic hypoplasia
16.7
14.1
22
13
I97.0
ICD-10 Finland
Postcardiotomy syndrome
13.2
14.0
24
18
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
41.8
14.0
17
*
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
5.1
14.0
29
56
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
13.9
746
5603
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
4.2
13.9
37
88
FM1AD
NOMESCO Finland
CT of heart
11.8
13.9
25
21
I48.3
ICD-10 Finland
Typical atrial flutter
4.8
13.8
31
64
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
29.6
13.7
18
6
GE1BE
NOMESCO Finland
Mediastinal ultrasound examinaiton through oesophagus
19.7
13.6
20
10
K91
ICPC
Cerebrovascular disease
4.4
13.6
34
77
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
3.8
13.6
41
107
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.8
13.4
228
1321
FM2FN
NOMESCO Finland
Intra cardiac shunt isotope imaging
137.7
13.3
14
*
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
137.7
13.3
14
*
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
2.7
13.3
69
251
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
4.0
13.3
37
91
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
13.3
726
5462
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
9.9
13.3
26
26
P85
ICPC
Mental retardation
3.7
13.2
41
109
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
12.6
13.2
23
18
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.2
13.2
51
157
Q22.5
ICD-10 Finland
Ebstein anomaly
39.3
13.0
16
*
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
13.0
1847
19788
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
12.9
199
1119
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
12.9
263
1600
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
27.9
12.8
17
6
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
22.2
12.7
18
8
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.0
12.7
147
754
Q90
ICD-10 Finland
Down syndrome
68.7
12.5
14
*
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
3.0
12.5
54
178
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
4.8
12.5
28
58
ZX199
NOMESCO Finland
Other rote
4.6
12.4
29
62
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
12.4
371
2476
FHB96
NOMESCO Finland
Other closure of congenital ventricular septal defect
+∞
12.4
12
*
Q21.2
ICD-10 Finland
Atrioventricular septal defect
+∞
12.4
12
*
I51.0
ICD-10 Finland
Cardiac septal defect, acquired
+∞
12.4
12
*
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
17.0
12.4
19
11
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.0
12.3
129
639
7AX01, ,
NOMESCO Finland
9.9
12.3
24
24
K99
ICPC
Cardiovascular disease other
3.1
12.3
50
159
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
3.7
12.0
37
98
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
15.6
12.0
19
12
R50.9
ICD-10 Finland
Fever, unspecified
1.5
11.9
442
3085
I44.1
ICD-10 Finland
Atrioventricular block, second degree
3.4
11.9
42
122
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
26.2
11.9
16
6
B01AE07
ATC
dabigatran etexilate; oral
2.6
11.9
69
266
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
17.7
11.9
18
10
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
20.9
11.9
17
8
FPK00
NOMESCO Finland
Implantation of electrocardiograph with loop recorder
5.0
11.8
25
49
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
3.9
11.8
34
86
FPD00
NOMESCO Finland
Maze procedure for atrial fibrillation
45.9
11.8
14
*
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
4.7
11.8
27
57
ZXY02
NOMESCO Finland
Neuropsychologist
4.5
11.7
28
61
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
11.5
445
3129
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
2.8
11.5
56
197
C02KX01
ATC
bosentan; oral
29.5
11.5
15
5
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
29.5
11.5
15
5
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
16.1
11.5
18
11
FJD20
NOMESCO Finland
Bypass of pulmonary valve with ventriculopulmonary prosthesis or homograft
63.9
11.5
13
*
74689
ICD-8 Finland
Congenital anomalies of heart, Aliae definitae
63.9
11.5
13
*
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
22.5
11.4
16
7
F82
ICD-10 Finland
Specific developmental disorder of motor function
2.8
11.4
56
198
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.8
11.4
181
1028
APX
HP
Other cardiac catheter operation
+∞
11.4
11
*
Q21
ICD-10 Finland
Congenital malformations of cardiac septa
+∞
11.4
11
*
7451A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[TRANSPOSITIO CORDIS COMPLETA]
118.0
11.3
12
*
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
9.9
11.3
22
22
I63.8
ICD-10 Finland
Other cerebral infarction
4.5
11.3
27
59
P07.3
ICD-10 Finland
Other preterm infants
2.6
11.3
62
233
I49.1
ICD-10 Finland
Atrial premature depolarization
2.4
11.2
79
334
H52.2
ICD-10 Finland
Astigmatism
2.3
11.1
82
354
K89
ICPC
Transient cerebral ischaemia
4.7
11.1
25
52
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.6
11.0
304
1991
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.2
10.9
88
394
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
10.9
566
4201
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
4.4
10.8
27
61
R00.2
ICD-10 Finland
Palpitations
1.7
10.8
197
1164
PD5AD
NOMESCO Finland
CT of aorta
2.7
10.8
55
199
R1260
NOMESCO Finland
Evaluation of communicative skills
2.8
10.7
54
194
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
2.5
10.6
63
246
B01AF01
ATC
rivaroxaban; oral
1.7
10.5
212
1286
Q21.3
ICD-10 Finland
Tetralogy of Fallot
59.0
10.5
12
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
59.0
10.5
12
*
Z2446
NOMESCO Finland
Social worker
1.6
10.4
243
1529
WX002
NOMESCO Finland
Sedation and analgesia
1.5
10.4
370
2557
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
13.9
10.3
17
12
5609
FHL
Other measure in this category
+∞
10.3
10
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
10.3
10
*
Q22.41
ICD-10 Finland
Tricuspid atresia
+∞
10.3
10
*
7456C
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[ASD CANALIS ATRIOVENTRICULARIS COMMUNIS]
+∞
10.3
10
*
GD1AD
NOMESCO Finland
Thorax CT examination
1.9
10.3
126
659
Q25.21
ICD-10 Finland
Interrupted aortic arch
108.1
10.3
11
*
FGE10
NOMESCO Finland
Replacement of tricuspid valve using biological prosthesis
108.1
10.3
11
*
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
108.1
10.3
11
*
FDE10
NOMESCO Finland
Ligature of patent ductus arteriosus
32.0
10.2
13
*
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
15.8
10.2
16
10
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
3.3
10.2
37
110
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.9
10.1
135
728
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
4.0
10.1
28
69
D68.8
ICD-10 Finland
Other specified coagulation defects
3.5
10.0
34
97
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
7.7
9.9
22
28
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.9
9.9
123
648
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
3.4
9.8
34
98
Q25.3
ICD-10 Finland
Stenosis of aorta
16.4
9.7
15
9
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
4.9
9.7
21
42
3A064, ,
NOMESCO Finland
12.0
9.7
17
14
Q24.6
ICD-10 Finland
Congenital heart block
25.6
9.7
13
5
Q24.0
ICD-10 Finland
Dextrocardia
25.6
9.7
13
5
UDC00
NOMESCO Finland
Ear microscopy
1.7
9.7
187
1122
FM1BD
NOMESCO Finland
Extensive CT of heart
8.0
9.7
21
26
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
8.0
9.7
21
26
AAL10
NOMESCO Finland
Intracranial endovascular thrombolysis
9.4
9.6
19
20
FJD96
NOMESCO Finland
Other operation on right ventricle outlet for congenital or acquired obstruction
54.0
9.6
11
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.4
9.6
394
2800
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
3.6
9.5
31
86
C08DA01
ATC
verapamil; systemic
2.2
9.4
78
354
1EA01, ,
NOMESCO Finland
14.8
9.4
15
10
AH3
HP
Treatment of arrhythmias, eg atrial fibrillation, in conjunction with other cardiac surgery
98.3
9.3
10
*
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
4.1
9.3
25
60
7454E
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[VSD MULTIPLEX]
+∞
9.3
9
*
Q21.32
ICD-10 Finland
Pulmonary atresia with Fallot ventricular septal defect
17.2
9.3
14
8
SPAT1097
SPAT
Recording of ECG
1.6
9.3
240
1549
K77
ICPC
Heart failure
3.1
9.2
37
117
RS221, ,
NOMESCO Finland
2.5
9.1
55
217
B01AC07
ATC
dipyridamole; systemic
2.6
9.1
52
200
74629
ICD-8 Finland
Congenital anomalies of heart, Tetralogy of Fallot
36.0
8.9
11
*
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
3.8
8.9
27
71
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.5
8.9
250
1643
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
18.3
8.8
13
7
Q20.00
ICD-10 Finland
Common arterial trunk
23.6
8.8
12
5
42700
ICD-8 Finland
Symptomatic heart disease, Congestive heart failure
23.6
8.8
12
5
I44.0
ICD-10 Finland
Atrioventricular block, first degree
3.5
8.8
29
81
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
7.3
8.8
20
27
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.6
8.7
184
1130
H01AC01
ATC
somatropin; parenteral
2.5
8.7
51
199
73
HP
Initial pacemaker installation
10.5
8.7
16
15
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
4.1
8.6
23
55
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
1.7
8.6
145
839
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.0
8.6
97
495
FM1CE
NOMESCO Finland
Ultrasound examination of heart through catheter
49.1
8.6
10
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.7
8.5
154
908
K92.1
ICD-10 Finland
Melaena
2.0
8.5
95
484
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.0
8.5
91
457
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.3
8.4
61
262
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
2.2
8.4
65
287
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
3.8
8.4
25
65
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
2.9
8.4
37
124
FPD96
NOMESCO Finland
Other operation for atrial fibrillation
27.0
8.4
11
*
AD1
HP
TVP
27.0
8.4
11
*
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
19.7
8.4
12
6
L04AD02
ATC
tacrolimus; systemic
2.7
8.4
45
168
XF405
NOMESCO Finland
Symptom ECG
3.7
8.3
26
70
ZX108
NOMESCO Finland
Inhalation
3.3
8.3
31
94
4168X
ICD-9 Finland
Chronic pulmonary heart disease, Other chronic pulmonary heart diseases
+∞
8.3
8
*
FFF96
NOMESCO Finland
Other operation for partially anomalous pulmonary veins
+∞
8.3
8
*
5501
FHL
Pulmonary artery stenosis
+∞
8.3
8
*
AC4
HP
MVP
12.5
8.3
14
11
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
8.2
401
2931
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.9
8.2
93
475
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
8.2
502
3808
PA6AG
NOMESCO Finland
Limited MRI examination of neck vasculature with high intensity magnet
4.1
8.2
22
53
Z95.3
ICD-10 Finland
Presence of xenogenic heart valve
9.3
8.1
16
17
M41.9
ICD-10 Finland
Scoliosis, unspecified
2.8
8.1
39
137
T14.5
ICD-10 Finland
Injury of blood vessel(s) of unspecified body region
4.8
8.1
18
37
R07.2
ICD-10 Finland
Precordial pain
2.6
8.1
46
177
XG460
NOMESCO Finland
Short time oxymetry
3.1
8.0
32
101
127
Kela drug reimbursment
Transplant complication
2.4
8.0
53
219
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
8.0
430
3195
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
4.1
7.9
21
50
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
21.6
7.9
11
5
I37.2
ICD-10 Finland
Pulmonary valve stenosis with insufficiency
21.6
7.9
11
5
FHE30
NOMESCO Finland
Repair of tetralogy of Fallot with transannular patch
21.6
7.9
11
5
Q87.06
ICD-10 Finland
Velocardiofacial syndrome
21.6
7.9
11
5
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.7
7.9
143
844
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
8.7
7.9
16
18
J45.1
ICD-10 Finland
Nonallergic asthma
1.6
7.9
191
1214
SPAT1260
SPAT
Consultation of another employee
1.4
7.9
361
2611
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.7
7.8
137
802
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
7.1
7.8
18
25
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
1.8
7.8
104
562
SPAT1263
SPAT
Sampling
1.3
7.8
940
7820
I71.09
ICD-10 Finland
Aortic dissection [regardless of location]
12.8
7.8
13
10
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.6
7.8
187
1187
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.3
7.8
57
247
7452A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Tetralogy of Fallot[TETRALOGIA FALLOT]
44.2
7.6
9
*
71
HP
Electrophysiological Special Examination
4.5
7.6
18
39
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
3.9
7.6
22
56
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
7.6
942
7857
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
2.3
7.6
54
231
EBA15
NOMESCO Finland
Extraction of multiple teeth
1.9
7.5
95
504
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
3.4
7.5
26
75
4302
FHL
Tooth patching under general anesthesia
18.0
7.5
11
6
FN1AD
NOMESCO Finland
CT of coronary arteries
2.5
7.5
44
172
FB1BC
NOMESCO Finland
Extensive angiography of arteria pulmonalis
24.5
7.5
10
*
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
24.5
7.5
10
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
24.5
7.5
10
*
GD1LA
NOMESCO Finland
GD
2.9
7.5
33
111
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
2.4
7.5
48
196
ZXA10
NOMESCO Finland
Bilateral
1.4
7.4
371
2721
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.8
7.4
118
672
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
2.7
7.4
37
133
Q89.7
ICD-10 Finland
Multiple congenital malformations, not elsewhere classified
8.7
7.4
15
17
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
9.8
7.4
14
14
FPH96
NOMESCO Finland
Other removal of cardiac pacemaker or cardioverter-defibrillator
6.0
7.4
19
31
FPW96
NOMESCO Finland
Other operation for arhythmia or disturbance of impulse propagation
6.0
7.4
19
31
Z3229
NOMESCO Finland
Other healthcare associate professional
1.6
7.4
193
1250
Q25.70
ICD-10 Finland
Aneurysm, congenital of pulmonary artery
78.6
7.4
8
*
F80.1
ICD-10 Finland
Expressive language disorder
2.4
7.3
50
210
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.7
7.3
130
765
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.0
7.3
73
358
Z2445
NOMESCO Finland
Psychologist
1.6
7.3
159
986
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
13.1
7.3
12
9
74709
ICD-8 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
13.1
7.3
12
9
742, ,
NOMESCO Finland
13.1
7.3
12
9
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
2.1
7.3
68
325
R55
ICD-10 Finland
Syncope and collapse
1.5
7.3
203
1333
FP1C5
NOMESCO Finland
Resting ECG, 15 leads
3.1
7.3
30
97
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
7.5
7.3
16
21
XX3DW
NOMESCO Finland
Time consuming IT work
1.6
7.3
175
1112
C09AA02
ATC
enalapril; systemic
1.4
7.2
281
1972
7459X
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Unspecified defect of septal closure
+∞
7.2
7
*
AE1
HP
Pulmonary artery thrombendarterectomy
+∞
7.2
7
*
FFF20
NOMESCO Finland
Anastomosis to left atrium from partially anomalous pulmonary veins
+∞
7.2
7
*
KC1JB
NOMESCO Finland
Miktiocystography with X-ray
4.3
7.2
18
41
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.7
7.2
137
821
H65.3
ICD-10 Finland
Chronic mucoid otitis media
1.7
7.2
122
709
R20.2
ICD-10 Finland
Paraesthesia of skin
1.6
7.2
149
913
3A019, ,
NOMESCO Finland
6.7
7.2
17
25
FPD10
NOMESCO Finland
Surgical ablation of atrial fibrillation
15.4
7.1
11
7
Q76.30
ICD-10 Finland
Hemivertebra fusion or failure of segmentation with scoliosis
15.4
7.1
11
7
C08DB01
ATC
diltiazem; oral
2.1
7.1
66
315
I50
ICD-10 Finland
Heart failure
2.5
7.1
43
171
R01.0
ICD-10 Finland
Benign and innocent cardiac murmurs
2.0
7.1
73
362
5512
FHL
Cleavage or ligation of the ductus arteriosus
29.5
7.1
9
*
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
2.6
7.0
40
154
Z50.0
ICD-10 Finland
Cardiac rehabilitation
4.1
7.0
19
46
N18
ICPC
Paralysis/weakness
2.6
7.0
38
143
H66.9
ICD-10 Finland
Otitis media, unspecified
1.4
7.0
311
2237
RL140, ,
NOMESCO Finland
3.1
7.0
28
89
FJE42
NOMESCO Finland
Percutaneous transluminal expansion of pulmonary valve
11.8
7.0
12
10
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
2.5
7.0
40
155
H52.0
ICD-10 Finland
Hypermetropia
2.0
7.0
76
385
H50.0
ICD-10 Finland
Convergent concomitant strabismus
2.6
6.9
37
138
PD5DG
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
9.8
6.9
13
13
WX870
NOMESCO Finland
Other postsurgical intensive care
5.5
6.9
19
34
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
6.9
1341
11728
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
6.2
6.8
17
27
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.8
6.8
91
493
Q87.4
ICD-10 Finland
Marfan syndrome
13.5
6.8
11
8
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.7
6.8
123
728
TKC20
NOMESCO Finland
Catheterisation of bladder
1.8
6.8
105
595
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
6.7
172
1108
Q93.5
ICD-10 Finland
Other deletions of part of a chromosome
10.7
6.7
12
11
Z95.4
ICD-10 Finland
Presence of other heart-valve replacement
10.7
6.7
12
11
WZC30
NOMESCO Finland
Teaching
1.4
6.7
316
2296
74619
ICD-8 Finland
Congenital anomalies of heart, Transposition of great vessels
39.2
6.7
8
*
TFW99
NOMESCO Finland
Other minor procedure in cardiac surgery
39.2
6.7
8
*
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
2.7
6.7
34
124
C02KX04
ATC
macitentan; oral
16.4
6.7
10
6
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
6.7
832
6920
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
6.7
331
2426
FKC50
NOMESCO Finland
Repair of mitral valve for insufficiency using prosthetic chord
6.0
6.6
17
28
R00.1
ICD-10 Finland
Bradycardia, unspecified
2.2
6.6
55
252
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
3.3
6.6
24
72
TJD20
NOMESCO Finland
Change of gastrostomy tube
3.2
6.6
25
77
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.2
6.5
50
221
J96.1
ICD-10 Finland
Chronic respiratory failure
2.6
6.5
35
131
P29.9
ICD-10 Finland
Cardiovascular disorder originating in the perinatal period, unspecified
12.0
6.5
11
9
5210A
ICD-9 Finland
Diseases of hard tissues of teeth, Dental caries
9.8
6.4
12
12
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.6
6.4
134
823
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
2.7
6.4
33
121
SPAT1301
SPAT
No procedures
1.3
6.4
654
5306
K73
ICPC
Congenital anomaly cardiovascular
68.5
6.4
7
*
Q20.60
ICD-10 Finland
Left isomerism of atrial appendages
68.5
6.4
7
*
Q90.1
ICD-10 Finland
Trisomy 21, mosaicism (mitotic nondisjunction)
68.5
6.4
7
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.6
6.4
147
926
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
14.0
6.3
10
7
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
2.2
6.3
50
225
H50.30
ICD-10 Finland
Intermittent esotropy
2.7
6.3
32
117
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
1.9
6.3
73
379
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
2.5
6.2
36
140
TK800
NOMESCO Finland
Hemodialysis
2.3
6.2
43
182
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
6.4
6.2
15
23
RK260, ,
NOMESCO Finland
6.4
6.2
15
23
I21.19
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
3.4
6.2
21
60
PA2BG
NOMESCO Finland
MRI examination of vessels in the head with high intensity magnet
3.4
6.2
21
60
7454C
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[LEFT VENTRICULAR AND RIGHT ATRIAL COMMUNICATION]
+∞
6.2
6
*
Q24.50
ICD-10 Finland
Congenital coronary artery-coronary fistula
+∞
6.2
6
*
5513
FHL
Coarctation resection, plastic or bypass
+∞
6.2
6
*
FFE10
NOMESCO Finland
Creation or expansion of ASD in open heart surgery
+∞
6.2
6
*
Q22.40
ICD-10 Finland
Congenital tricuspid stenosis
+∞
6.2
6
*
H53.1
ICD-10 Finland
Subjective visual disturbances
1.6
6.2
141
885
ZX120
NOMESCO Finland
Intravenous
1.5
6.2
188
1258
AB2
HP
AVR bio, stent
9.1
6.2
12
13
AB4AE
NOMESCO Finland
Spinal ultrasound examination
17.7
6.2
9
5
I36.0
ICD-10 Finland
Nonrheumatic tricuspid (valve) stenosis
17.7
6.2
9
5
FK1AC
NOMESCO Finland
Right cardioangiography
26.2
6.2
8
*
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
1.6
6.2
131
809
K40.9
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
1.5
6.1
190
1277
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
6.1
672
5496
C10AX09
ATC
ezetimibe; oral
1.4
6.1
272
1958
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
2.2
6.1
46
203
DFF20
NOMESCO Finland
Audiometry for children
2.4
6.1
38
154
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
6.0
1843
16795

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
531
1029
6.06
262.34
4.0
6.4
95.99
93.88
%
1.28
524
1013
307
352
9.52
243.19
1.1
1.2
115.96
111.09
%
1.34
300
328
1219
4876
3.67
231.36
5.2
3.5
1200.44
1163.08
ng/l
0.09
1072
4090
294
344
9.28
228.99
1.1
1.2
—
—
—
0
0
939
3351
3.69
208.62
3.6
3.6
30.85
29.77
s
4.98
922
3279
1645
8391
3.40
203.38
27.7
11.8
1.45
1.19
inr
40.66
1385
6972
478
1109
4.92
189.61
3.1
4.7
21.26
21.49
s
0.36
404
1028
268
396
7.26
170.42
1.3
1.3
3.72
4.87
u/ml
0.60
130
191
203
285
7.47
134.64
2.4
2.4
—
—
—
0
0
445
1264
3.94
133.01
4.1
3.7
190.36
184.73
ng/l
0.09
401
1139
1120
5737
2.57
117.34
5.8
5.5
81.76
90.53
%
23.74
1104
5634
1027
5421
2.39
96.41
2.6
2.7
—
—
—
0
0
1196
6992
2.22
85.49
2.7
2.7
—
—
—
0
0
1049
5954
2.20
79.19
2.8
2.3
213.77
226.27
u/l
0.18
1011
5696
1513
9995
2.12
75.81
3.2
3.0
—
—
estimate
—
0
0
101
126
8.12
73.76
1.1
1.1
1.06
1.06
ratio
0.26
90
107
722
3652
2.28
70.95
4.5
3.7
1058.22
523.01
ng/l
1.91
567
2509
91
106
8.67
70.24
1.2
1.2
15.86
10.77
u/ml
—
7
13
701
3590
2.24
66.21
6.3
6.2
0.83
0.82
mmol/l
1.23
679
3423
1777
12867
2.06
64.57
8.6
6.1
6.17
6.48
mmol/l
12.64
1710
12116
1112
6869
2.00
63.27
4.5
3.4
44.81
54.06
ng/l
0.31
776
4285
75
80
9.42
61.90
1.2
1.3
28.39
28.16
s
0.09
75
80
48
24
19.92
61.25
2.4
3.0
99.02
98.08
g/l
0.14
48
24
288
995
3.06
61.20
4.7
5.6
3.04
3.23
g/l
1.78
279
963
62
57
10.88
56.81
3.7
7.9
4.97
5.13
kpa
0.47
62
57
467
2213
2.29
51.84
9.1
11.6
7.60
7.68
mmol/l
0.10
459
2151
1384
9931
1.76
43.46
12.6
9.1
1.21
1.22
mmol/l
5.07
1318
9310
601
3461
1.90
38.38
8.4
8.9
1.17
1.15
mmol/l
0.88
580
3254
305
1371
2.33
37.62
2.3
2.3
15.50
7.63
ug/l
4.75
271
1219
415
2148
2.06
35.85
16.4
9.9
5.26
5.13
kpa
1.79
408
2075
415
2149
2.06
35.80
16.4
9.9
13.47
12.89
kpa
1.08
408
2079
260
1118
2.41
35.39
22.2
12.9
16.18
16.04
%
0.35
254
1085
412
2137
2.05
35.35
16.5
9.9
0.76
0.69
mmol/l
0.14
363
1768
413
2151
2.04
35.01
16.5
9.9
7.41
7.41
ph
0.12
190
1125
286
1290
2.31
34.90
19.8
12.3
94.51
94.22
%
0.27
286
1285
1450
10939
1.65
34.46
11.6
9.2
1.21
1.22
mmol/l
3.73
1246
9694
2471
21847
2.49
33.65
24.3
16.4
139.52
139.61
mmol/l
1.15
2453
21417
377
1930
2.06
33.40
17.2
10.5
95.91
95.47
%
0.51
369
1872
2471
21888
2.46
32.76
24.4
16.5
3.97
3.95
mmol/l
1.94
2450
21404
480
2739
1.87
30.82
15.9
11.0
—
—
—
0
0
437
2430
1.91
30.35
9.9
8.1
7.42
7.41
ph
2.46
370
1980
47
68
6.87
30.13
1.2
1.1
—
—
—
0
0
439
2463
1.89
29.61
9.9
8.0
5.18
5.06
kpa
3.04
433
2383
32
29
10.92
29.50
1.0
1.0
—
—
—
0
0
1587
12526
1.59
29.06
7.0
7.8
0.58
0.57
e9/l
0.86
1346
10690
1587
12530
1.59
28.98
7.0
7.9
0.04
0.04
e9/l
0.75
1350
10696
342
1802
1.98
27.69
16.8
10.4
121.28
122.46
g/l
0.47
336
1767
526
3189
1.77
27.36
3.3
2.9
21.54
22.83
%
1.60
490
3010
1605
12815
1.57
26.98
7.1
7.9
1.94
2.07
e9/l
3.42
1386
11235
998
7193
1.57
26.19
1.6
1.6
—
—
—
0
0
735
4927
1.64
26.12
2.9
2.4
1.16
1.20
mg/l
0.13
565
3717
1611
12926
1.56
26.05
7.5
8.3
0.19
0.20
e9/l
2.55
1388
11232
1476
11627
1.54
25.84
7.4
8.1
0.66
0.67
%
0.28
1422
11022
1478
11664
1.54
25.52
7.4
8.1
8.84
8.60
%
2.80
1426
11063
1209
9136
1.54
25.46
6.1
6.0
36.38
36.59
g/l
0.63
1136
8636
1474
11637
1.54
25.31
7.4
8.0
2.86
2.96
%
0.90
1420
11031
1385
10794
1.53
25.20
7.8
7.0
15.92
13.46
umol/l
2.83
1301
10266
553
3473
1.71
25.13
3.2
2.9
2.44
2.41
g/l
0.84
512
3249
351
1950
1.88
24.10
10.2
8.5
—
—
—
0
0
583
3763
1.66
23.72
3.3
2.9
12.75
13.65
umol/l
2.49
542
3551
1503
12037
1.51
23.23
7.3
8.0
28.95
30.72
%
7.81
1454
11533
768
5366
1.56
22.30
4.5
4.4
—
—
—
0
0
1473
11836
1.49
21.75
7.1
7.9
55.92
54.41
%
5.02
1438
11406
2466
22370
2.07
21.64
19.4
14.3
23.22
22.69
mg/l
0.37
2088
17794
1404
11199
1.48
21.33
12.6
11.7
0.00
0.00
e9/l
0.50
1118
8994
486
3084
1.66
20.83
6.6
8.0
7.37
7.37
ph
0.02
315
1928
484
3085
1.65
20.35
6.3
7.9
5.93
5.80
kpa
2.18
476
3012
472
3023
1.64
19.39
6.5
8.0
1.55
1.39
mmol/l
0.46
414
2531
384
2339
1.71
19.08
6.2
8.6
24.01
23.76
mmol/l
1.03
384
2325
437
2770
1.65
18.64
6.2
7.8
5.13
4.86
kpa
1.31
431
2704
1646
13733
1.45
18.58
9.6
10.6
3.97
3.92
e9/l
0.33
1412
11803
219
1131
1.98
18.56
4.4
7.1
0.64
0.61
%
0.65
219
1126
41
84
4.84
18.40
3.3
3.9
4.73
3.58
%
—
10
41
2515
23155
2.14
18.37
22.9
17.0
71.70
71.23
umol/l
0.31
2503
22901
220
1146
1.96
18.18
4.5
7.1
1.21
1.23
%
0.07
220
1137
102
388
2.64
17.92
5.4
5.1
1.96
2.38
mmol/l
0.99
65
239
263
1464
1.84
17.74
3.9
4.1
1.22
1.23
mmol/l
0.86
245
1266
74
246
3.00
16.72
3.0
3.4
0.81
0.81
nmol/l
0.01
58
205
224
1207
1.89
16.72
9.9
14.9
1.24
1.22
mg/l
0.17
218
1154
818
6091
1.45
16.48
2.8
2.6
3.04
2.64
mg/l
3.34
723
5338
806
6001
1.45
16.19
4.5
4.2
7.40
7.39
ph
1.06
622
4255
105
453
2.32
14.15
4.5
4.3
—
—
—
0
0
1836
15996
1.40
13.75
8.9
7.8
89.34
87.10
u/l
0.71
1753
15234
162
840
1.95
13.57
1.8
2.1
1.26
1.44
g/l
1.63
133
743
1857
16233
1.40
13.47
4.9
4.4
9.33
10.10
mm/h
2.05
1764
15309
230
1342
1.74
13.19
5.7
7.3
130.00
129.96
g/l
0.01
224
1307
48
147
3.24
12.52
1.8
1.4
—
—
—
0
0
96
421
2.28
12.49
3.0
2.9
16.72
16.82
%
0.13
96
409
81
330
2.45
12.43
7.4
7.7
11.60
10.93
mg/l
0.49
71
310
152
797
1.92
12.33
1.1
1.3
—
—
—
0
0
351
2324
1.55
12.16
3.1
3.1
0.20
0.21
g/l
1.75
341
2202
430
2979
1.49
12.04
2.5
2.0
—
—
—
0
0
79
329
2.39
11.58
2.4
2.2
1.83
1.72
mmol/l
0.37
79
323
1406
11928
1.33
11.36
4.0
3.4
93.93
96.42
ug/l
0.20
1313
11315
649
4932
1.38
10.83
3.5
3.0
5.55
6.48
e6/l
1.04
595
4465
49
166
2.93
10.82
1.9
1.4
1598.24
2020.16
e6/l
0.30
34
110
46
151
3.02
10.73
3.6
5.9
115.16
73.41
mg/l
1.45
37
132
1643
14320
1.32
10.61
5.1
4.5
375.71
1758.65
e6/l
1.86
28
180
384
2664
1.48
10.60
3.7
4.4
1.79
1.65
%
1.55
348
2458
45
147
3.03
10.59
1.9
1.4
104794.78
28442.15
e6/l
0.91
27
79
819
6484
1.34
10.44
3.8
3.6
0.44
0.36
e6/l
0.34
624
4671
908
7347
1.32
9.82
4.1
3.8
142.71
57.59
e6/l
0.38
708
5518
50
182
2.72
9.71
1.7
1.4
33.92
32.43
g/l
0.36
44
163
877
7076
1.32
9.64
3.3
3.4
2.36
2.36
mmol/l
0.99
806
6514
815
6511
1.32
9.60
2.9
2.8
59.80
71.73
u/l
0.48
747
6081
133
734
1.81
9.25
3.7
2.4
696.22
365.97
ug/l
0.86
126
691
118
633
1.86
9.00
1.1
1.3
—
7.66
—
0
10
781
6255
1.31
8.91
4.2
3.8
0.01
0.00
estimate
0.16
288
2236
236
1531
1.56
8.91
2.2
3.0
65.30
66.63
g/l
1.67
222
1436
265
1776
1.51
8.62
4.1
3.7
—
—
—
0
0
231
1504
1.55
8.58
3.9
3.7
4.67
4.70
pmol/l
0.13
213
1366
47
179
2.60
8.40
46.7
48.2
7.39
6.80
ug/l
1.06
47
162
930
7679
1.29
8.30
4.1
3.8
33.76
31.75
u/l
0.42
888
7313
276
1881
1.49
8.27
4.7
5.3
0.05
0.27
%
0.70
80
470
1032
8657
1.27
8.04
5.0
4.5
111.35
76.07
e6/l
0.31
748
5854
289
2002
1.46
7.98
3.6
3.8
74.40
68.97
e9/l
1.37
196
1362
376
2743
1.40
7.80
4.6
4.3
8.47
6.98
umol/l
0.82
333
2363
171
1068
1.61
7.61
9.8
7.5
24.71
24.37
mmol/l
0.54
165
1026
38
137
2.74
7.58
1.9
1.6
—
—
—
0
0
2218
20528
1.35
7.38
6.0
5.2
1.94
1.89
mu/l
1.12
2097
19368
266
1847
1.46
7.25
4.5
4.7
0.75
0.64
%
0.42
91
558
99
545
1.81
7.02
7.7
7.6
1.21
1.27
mmol/l
0.30
88
479
87
460
1.88
7.01
1.9
1.9
—
—
—
0
0
87
460
1.88
7.01
1.9
1.9
—
—
—
0
0
38
143
2.62
7.01
1.9
1.4
—
—
—
0
0
2160
19956
1.32
6.95
23.8
18.1
13.51
13.39
%
3.93
2144
19707
553
4353
1.31
6.91
3.6
3.0
547.65
543.67
mosm/kgh2o
0.15
501
3819
265
1856
1.44
6.90
4.7
5.1
0.15
0.10
%
0.35
78
504
1951
17796
1.27
6.90
5.0
4.3
14.76
14.60
pmol/l
2.44
1814
16503
138
839
1.64
6.87
1.4
1.7
1.15
1.18
g/l
0.60
132
802
274
1940
1.43
6.73
4.7
5.0
1.09
0.88
%
0.55
88
589
86
460
1.86
6.70
2.0
1.9
—
—
—
0
0
86
460
1.86
6.70
2.0
1.9
—
—
—
0
0
374
2794
1.36
6.68
1.8
1.7
1226.04
1173.80
nmol/l
0.47
278
2151
43
178
2.39
6.53
3.5
4.7
1.12
0.76
index
1.15
43
178
442
3403
1.33
6.44
1.4
1.5
475.24
493.80
titre
0.08
84
681
53
243
2.16
6.36
2.4
2.2
31.30
32.54
pg
0.98
53
243
1117
9647
1.23
6.24
3.4
3.4
6.22
6.24
ph
0.16
571
5296
360
2703
1.35
6.21
1.8
1.5
—
—
—
0
0
1354
11938
1.22
6.16
4.1
3.8
8.89
5.31
estimate
0.23
307
2389
748
6192
1.25
6.15
3.1
2.9
—
—
—
0
0
881
7451
1.24
5.92
6.2
7.0
—
—
—
0
0
15
25
5.90
5.88
1.1
1.2
—
—
—
0
0
105
625
1.67
5.72
3.0
3.5
6.13
4.18
index
0.38
67
345
93
538
1.72
5.63
2.7
2.5
133.58
131.29
g/l
0.44
76
442
1353
11992
1.21
5.63
4.1
3.8
0.01
0.14
estimate
0.48
289
2280
55
269
2.02
5.62
3.1
4.8
5.80
6.74
mmol/l
2.70
48
232
76
415
1.82
5.60
3.4
3.7
3.97
3.95
e9/l
0.03
76
415
151
988
1.53
5.55
1.4
1.9
3.51
7.40
iu/ml
2.87
29
217
2581
24723
1.72
5.54
29.6
21.6
29.94
29.93
pg
0.14
2567
24503
1334
11818
1.21
5.54
4.1
3.8
0.00
0.00
estimate
0.50
302
2375
2581
24725
1.71
5.51
29.7
21.6
4.51
4.55
e12/l
4.38
2532
24063
2581
24725
1.71
5.51
31.9
22.4
39.98
40.69
%
2.34
2567
24496
2581
24731
1.71
5.42
30.3
21.9
133.70
135.39
g/l
7.05
2569
24516
2580
24720
1.70
5.41
29.6
21.6
89.73
89.56
fl
0.96
2566
24499
2581
24734
1.70
5.38
29.7
21.7
6.84
6.80
e9/l
0.27
2533
24065
250
1814
1.39
5.35
6.0
5.9
75.91
73.69
ng/l
0.19
219
1662
50
241
2.05
5.33
2.2
2.1
0.93
0.90
%
0.14
31
150
365
2809
1.32
5.30
2.0
1.7
—
—
—
0
0
2579
24715
1.68
5.30
29.7
21.7
248.49
259.27
e9/l
14.28
2536
24119
165
1112
1.48
5.28
1.8
2.5
—
—
—
0
0
127
814
1.55
5.15
1.4
1.7
0.23
0.22
g/l
0.10
122
778
13
23
5.56
4.97
1.2
1.2
—
—
—
0
0
656
5465
1.23
4.93
1.7
1.6
19.33
20.08
nmol/l
0.74
550
4732
145
967
1.49
4.91
4.8
5.9
355.02
392.42
mg/l
0.15
98
564
110
695
1.57
4.77
2.5
2.1
3.06
11.74
iu/l
0.58
36
301
145
982
1.47
4.57
2.2
2.1
0.08
0.77
estimate
0.43
36
332
2026
18851
1.22
4.46
5.7
5.5
37.57
38.23
mmol/mol
3.30
1923
17898
131
874
1.49
4.45
1.2
1.3
3.50
1.00
u/ml
—
5
60
30
128
2.31
4.36
5.4
3.9
—
—
—
0
0
452
3666
1.25
4.30
2.5
2.7
2.42
2.44
mmol/l
2.58
403
3271
43
215
1.97
4.21
2.2
3.1
—
—
—
0
0
353
2790
1.28
4.18
1.3
1.3
—
—
—
0
0
634
5348
1.21
4.13
5.1
4.9
—
—
—
0
0
109
717
1.51
4.00
2.3
2.0
1.35
1.73
ug/l
0.31
97
637
63
364
1.71
3.94
10.0
9.5
10.59
11.46
mmol/l
1.23
56
331
596
5021
1.21
3.92
3.7
3.1
341.90
330.74
umol/l
1.81
526
4539
63
365
1.71
3.90
10.0
9.5
106.50
105.35
mmol/l
1.63
56
332
331
2619
1.27
3.89
1.2
1.3
—
—
—
0
0
19
69
2.71
3.85
1.1
1.3
7.45
7.37
ph
1.19
14
49
992
8753
1.17
3.83
3.9
3.5
1.97
0.02
estimate
0.49
255
1977
45
237
1.87
3.82
1.3
1.3
—
—
—
0
0
1647
15136
1.17
3.77
4.0
3.6
45.09
42.18
u/l
0.68
1585
14448
57
328
1.72
3.64
3.2
3.9
1.01
1.40
%
0.67
52
301
274
2138
1.28
3.61
1.3
1.4
171.78
302.04
u/ml
1.66
256
2008
352
2835
1.25
3.56
2.6
3.1
4.15
4.75
e9/l
1.32
311
2516
13
35
3.65
3.50
1.1
1.3
—
—
—
0
0
98
650
1.49
3.50
3.3
3.2
55.05
55.78
%
0.22
98
650
95
629
1.50
3.43
1.4
2.8
—
—
—
0
0
31
150
2.04
3.38
1.7
1.6
30.05
36.39
%
0.37
19
105
216
1652
1.30
3.33
2.3
2.4
20.06
19.49
au/ml
0.03
17
179
186
2350
0.76
3.30
1.3
1.3
—
—
—
0
0
65
399
1.61
3.28
2.1
2.2
71.07
69.82
mmol/l
0.08
54
342
741
6463
1.17
3.20
3.7
3.1
0.39
0.06
estimate
0.65
260
1923
217
1671
1.30
3.19
4.4
4.3
7.34
7.35
ph
0.15
158
1238
19
77
2.43
3.15
1.5
1.4
2.86
4.20
%
—
7
15
154
1137
1.35
3.05
1.8
2.0
—
—
—
0
0
100
688
1.44
3.01
1.2
1.3
2.14
4.07
u/ml
—
9
56
246
1948
1.26
2.91
2.0
2.0
0.07
0.01
estimate
0.39
43
438
485
4115
1.19
2.90
3.2
3.3
0.97
0.98
e6/l
0.02
257
2140
271
2171
1.25
2.90
3.0
3.5
9.93
10.04
g/l
0.15
258
2048
112
793
1.40
2.89
8.6
6.3
1.73
1.57
%
1.19
106
752
99
686
1.43
2.88
1.3
1.3
5.96
10.40
u/ml
0.56
17
96
268
2154
1.24
2.79
4.9
4.4
34.71
31.92
%
3.91
204
1526
124
899
1.37
2.79
5.6
4.5
25.07
24.99
mmol/l
0.09
119
859
104
732
1.41
2.79
2.1
1.9
—
—
—
0
0
86
585
1.45
2.77
1.7
2.3
10.30
10.35
g/l
0.04
77
536
197
1528
1.28
2.77
1.3
1.3
22.11
47.83
au/ml
1.54
11
86
282
2286
1.23
2.72
1.4
1.4
—
—
—
0
0
965
8669
1.14
2.69
1.9
1.9
1.27
1.36
mmol/l
3.03
802
7587
41
237
1.70
2.66
1.1
1.1
—
—
—
0
0
51
313
1.61
2.64
1.5
1.5
58.21
104.90
mu/l
0.63
46
282
28
144
1.91
2.64
1.1
1.1
1276.39
1563.72
miu/ml
0.92
28
144
60
383
1.55
2.63
2.6
4.4
6.93
54.76
u/ml
0.86
60
377
16
66
2.38
2.59
3.3
3.1
15.06
27.03
mg/l
—
8
28
102
726
1.39
2.58
9.5
6.6
0.90
0.88
%
0.13
96
685
455
3881
1.18
2.56
3.5
3.4
2.87
2.63
e6/l
0.18
222
1907
36
203
1.75
2.55
1.6
1.7
56.73
55.52
%
0.07
26
138
6
11
5.35
2.50
1.0
1.1
40.20
35.61
s
—
6
11
21
100
2.06
2.45
1.2
1.4
174.33
164.86
mmol/24h
0.27
21
100
41
243
1.66
2.45
1.5
3.6
—
—
—
0
0
95
676
1.39
2.43
1.3
2.5
3.60
3.56
mmol/l
0.19
88
648
1997
18867
1.14
2.38
4.5
3.9
1.18
1.27
mmol/l
8.35
1886
17718
80
556
1.42
2.35
2.8
2.5
—
—
—
0
0
215
1723
1.24
2.33
1.9
2.0
1.09
1.17
g/l
0.58
209
1625
7
17
4.04
2.31
2.4
2.5
—
—
—
0
0
948
8584
1.13
2.25
2.1
2.0
95.95
96.98
pmol/l
0.29
541
4659
202
1619
1.24
2.20
3.4
4.3
13.82
23.78
ug/l
0.45
160
1281
2047
19406
1.14
2.19
4.9
4.4
5.69
5.78
mmol/l
2.69
1897
18081
96
699
1.36
2.17
2.0
2.0
124.15
119.73
au/ml
0.14
34
250
22
391
0.55
2.15
1.2
1.4
5.47
13.74
u/ml
0.60
12
220
21
106
1.95
2.13
1.3
1.2
—
—
—
0
0
239
1960
1.21
2.10
1.3
1.3
132.87
145.49
u/ml
0.21
91
683
6
15
3.92
2.00
3.7
1.3
—
—
—
0
0
69
485
1.40
1.95
1.2
1.2
—
—
—
0
0
118
901
1.30
1.95
1.3
1.2
—
—
—
0
0
9
32
2.76
1.94
2.1
2.1
—
—
—
0
0
2109
20080
1.14
1.94
5.3
4.6
4.34
4.63
mmol/l
34.70
2014
19078
31
183
1.67
1.94
31.9
37.1
127.63
139.95
ug/l
0.34
24
165
441
3836
1.15
1.93
1.7
1.7
457.26
36914614.73
pmol/l
3.93
353
3286
33
510
0.63
1.92
1.1
1.2
53.00
1119.33
iu/ml
—
9
131
5
11
4.46
1.90
6.2
4.8
534.20
397.36
umol/l
—
5
11
28
162
1.70
1.88
1.1
1.1
—
—
—
0
0
9
33
2.68
1.88
1.6
1.6
—
—
—
0
0
192
1561
1.22
1.87
2.1
2.4
10622.59
7195.10
u/l
0.55
62
567
16
77
2.04
1.86
1.3
1.6
1.07
0.97
iu/ml
—
9
44
869
7907
1.11
1.83
2.0
2.0
—
—
—
0
0
15
71
2.07
1.82
1.4
1.6
0.00
0.04
estimate
0.49
15
71
20
106
1.85
1.80
1.6
1.9
92.03
101.40
ng/l
0.24
20
106
90
672
1.32
1.77
1.4
2.7
9.97
37.05
e6/l
1.17
72
483
2391
22997
1.18
1.77
13.6
11.3
26.21
26.29
u/l
0.07
2346
22440
194
1589
1.21
1.76
3.6
2.7
0.26
0.40
e6/l
0.71
188
1520
108
830
1.29
1.73
1.3
1.3
—
—
—
0
0
90
678
1.31
1.68
1.5
2.7
218.27
817.06
e6/l
1.38
74
512
78
576
1.34
1.67
5.3
4.0
1.35
1.39
mmol/l
0.11
78
567
2093
19972
1.12
1.66
5.2
4.5
1.42
1.45
mmol/l
2.59
1991
18859
7
25
2.75
1.61
2.9
3.8
4.34
4.65
mmol/l
—
7
25
86
652
1.30
1.56
2.9
3.6
82.66
2366.34
u/ml
0.86
78
559
2117
20236
1.12
1.55
5.8
5.1
2.53
2.74
mmol/l
24.01
2014
19139
76
965
0.76
1.53
1.1
1.1
0.71
0.65
ratio
0.25
11
93
20
327
0.60
1.52
1.1
1.2
0.59
2.33
u/ml
1.04
13
177
75
953
0.76
1.52
1.5
1.5
68.93
59.52
ug/l
1.04
60
817
631
5703
1.11
1.48
3.7
3.7
56.88
55.72
mg/l
0.04
397
3809
91
702
1.28
1.46
1.5
1.4
302.16
310.33
ug/g
0.14
52
392
9
37
2.39
1.46
2.6
1.5
37.29
24.26
g/l
—
9
26
53
378
1.38
1.45
3.1
3.4
1289.15
1476.04
e6/l
0.91
41
297
28
176
1.56
1.43
1.6
2.0
—
—
—
0
0
151
1758
0.83
1.42
1.7
1.9
—
—
—
0
0
82
1019
0.78
1.42
1.1
1.1
1.45
1.52
g/l
1.56
82
1019
15
79
1.86
1.41
2.1
2.2
28.27
30.22
%
0.17
15
79
73
553
1.30
1.36
4.7
3.7
12.07
8.26
umol/l
0.52
57
441
85
1044
0.79
1.35
1.1
1.1
0.81
0.88
g/l
1.64
85
1044
53
693
0.74
1.34
1.0
1.1
1.04
0.58
u/ml
0.19
26
310
17
95
1.76
1.34
1.6
2.7
16.30
16.62
%
0.14
17
95
41
284
1.42
1.34
5.0
3.5
1.66
1.69
umol/l
0.13
41
272
154
1274
1.19
1.32
1.2
1.2
—
—
—
0
0
698
6378
1.10
1.31
1.6
1.7
2.00
2.05
g/l
0.34
451
3778
46
612
0.73
1.31
3.3
2.3
0.80
0.76
nmol/l
0.15
39
524
24
149
1.58
1.30
2.0
2.2
—
—
—
0
0
9
42
2.10
1.30
1.3
1.1
—
—
—
0
0
143
1657
0.84
1.30
1.8
2.0
—
—
—
0
0
77
592
1.28
1.30
1.2
1.2
30.67
48.78
u/ml
—
6
49
8
35
2.24
1.25
2.3
2.7
—
—
—
0
0
42
297
1.39
1.24
1.5
1.4
319.48
386.21
pmol/l
0.56
33
255
27
175
1.52
1.24
1.4
1.3
64457.27
138077.45
e6/l
0.47
22
121
17
98
1.70
1.22
1.4
1.2
—
—
—
0
0
42
298
1.39
1.22
3.0
4.2
—
—
—
0
0
72
555
1.28
1.21
5.4
4.1
25.86
22.94
nmol/l
0.84
72
541
633
5786
1.09
1.18
4.4
4.3
39.56
8.93
mg/mmol
0.55
392
3775
24
154
1.53
1.16
2.3
3.2
849.08
1092.94
u/ml
0.45
24
154
0
35
0.00
1.14
0.0
1.2
—
—
—
0
0
21
131
1.57
1.14
1.7
5.0
207.17
154.18
umol/l
—
6
77
251
2187
1.14
1.14
2.6
2.5
41.49
61.25
u/l
0.40
220
1814
8
151
0.52
1.14
1.3
1.6
0.49
0.49
e9/l
—
8
151
35
473
0.72
1.13
1.1
1.1
1.67
4.08
eliau/ml
1.62
18
186
155
1759
0.85
1.13
2.2
2.3
6.13
6.14
ph
0.07
94
1147
107
871
1.21
1.12
1.7
1.7
282.53
210.68
u/ml
1.51
66
458
105
854
1.21
1.11
1.3
1.2
—
—
—
0
0
156
1767
0.86
1.11
1.7
2.0
—
—
—
0
0
26
172
1.48
1.10
1.2
1.1
—
—
—
0
0
14
79
1.74
1.09
1.2
1.6
77.34
88.03
nmol/24h
0.37
14
79
86
688
1.23
1.08
1.1
1.2
—
—
—
0
0
90
1066
0.82
1.07
1.1
1.1
—
—
—
0
0
158
1781
0.86
1.07
1.8
2.0
—
—
—
0
0
454
4107
1.10
1.06
1.4
1.3
17.77
26.99
iu/ml
3.17
121
1153
86
1020
0.82
1.04
1.1
1.2
3.35
2.85
u/ml
0.19
56
664
89
718
1.22
1.04
1.1
1.1
13.98
19.60
au/ml
0.32
20
132
13
73
1.75
1.04
1.2
1.4
85.31
94.79
umol/l
0.62
13
68
59
729
0.79
1.04
1.5
1.6
—
—
—
0
0
47
351
1.32
1.03
1.5
1.9
—
1578.18
—
0
11
158
1774
0.86
1.02
1.7
2.0
—
—
—
0
0
58
714
0.79
1.00
1.5
1.5
—
—
—
0
0
16
97
1.62
0.99
2.4
2.5
2136.87
2039.87
ml
0.18
16
88
33
235
1.38
0.98
1.1
1.2
24.93
37.01
mg/l
2.99
28
191
28
194
1.42
0.97
1.2
1.2
0.46
0.59
ratio
3.92
21
110
30
402
0.73
0.96
1.3
1.4
1.62
3.14
u/ml
0.85
24
249
44
331
1.31
0.93
3.6
3.5
328.19
206.97
e6/l
1.42
32
251
96
1111
0.84
0.92
1.6
1.5
—
—
—
0
0
17
251
0.66
0.92
1.4
1.6
7.74
7.69
mmol/l
0.04
17
243
20
131
1.50
0.92
1.0
1.1
—
—
—
0
0
19
123
1.52
0.92
1.1
1.2
309.48
200.23
iu/ml
0.75
19
123
191
2095
0.88
0.90
1.7
1.6
3.16
3.44
mmol/l
2.60
137
1403
65
778
0.81
0.89
1.1
1.1
7.41
5.78
u/ml
0.26
40
460
17
108
1.54
0.89
4.6
3.2
83.48
104.55
ug/l
0.33
17
108
20
132
1.49
0.89
1.0
1.0
—
—
—
0
0
109
1243
0.85
0.89
2.2
2.7
—
—
—
0
0
127
1430
0.86
0.88
1.9
2.0
—
—
—
0
0
58
700
0.81
0.87
1.5
1.5
1.28
1.27
mm
0.05
37
510
16
101
1.55
0.86
2.0
1.7
1.18
3.63
u/field
0.81
11
78
189
1654
1.13
0.85
2.0
1.7
19.69
21.24
iu/l
0.29
147
1266
24
167
1.41
0.83
1.2
1.2
—
—
—
0
0
18
118
1.50
0.83
3.3
2.3
614.77
630.78
ml
0.08
13
81
174
1517
1.13
0.83
1.6
1.6
—
—
—
0
0
62
737
0.82
0.82
1.1
1.1
8.00
9.05
u/ml
0.17
36
410
14
87
1.58
0.81
1.7
1.3
—
—
—
0
0
14
87
1.58
0.81
1.7
1.3
—
—
—
0
0
14
87
1.58
0.81
1.7
1.3
—
—
—
0
0
12
72
1.63
0.79
2.7
2.5
—
—
—
0
0
20
136
1.44
0.79
2.3
2.4
2.42
2.10
u/field
0.09
12
83
10
57
1.72
0.78
1.2
1.2
—
—
—
0
0
131
1127
1.15
0.78
1.7
1.8
—
—
—
0
0
11
65
1.66
0.77
1.1
1.2
—
—
—
0
0
290
2615
1.10
0.77
3.1
2.4
355.74
364.06
nmol/l
0.26
275
2462
83
690
1.18
0.76
1.2
1.2
—
—
—
0
0
759
7105
1.06
0.76
1.5
1.6
0.89
2.20
u/ml
7.20
208
1728
9
53
1.66
0.74
3.6
2.0
—
—
—
0
0
11
66
1.63
0.73
1.3
1.7
0.23
0.25
iu/ml
—
6
42
42
327
1.26
0.73
3.4
3.5
463.43
594.57
e6/l
1.35
30
241
14
203
0.67
0.73
1.2
1.3
3.55
11.15
u/ml
0.81
14
192
510
4724
1.07
0.70
5.2
4.9
1.66
2.28
ug/l
1.98
442
4309
94
1059
0.86
0.70
1.1
1.2
6.70
5.55
u/ml
0.28
58
723
20
140
1.40
0.70
1.1
1.2
—
—
—
0
0
82
688
1.17
0.70
1.3
1.2
—
—
—
0
0
92
1037
0.86
0.69
1.1
1.2
1.28
1.12
u/ml
0.12
52
636
27
200
1.32
0.68
1.6
1.7
—
—
—
0
0
102
1139
0.87
0.68
1.7
1.7
0.28
0.29
mg/l
0.03
37
523
14
92
1.49
0.66
1.6
2.1
—
—
—
0
0
24
309
0.76
0.64
1.6
2.1
—
—
—
0
0
416
3842
1.07
0.63
2.7
2.9
125.39
104.34
ug/g
0.44
330
3120
32
246
1.28
0.63
1.1
1.1
—
—
—
0
0
33
256
1.27
0.61
1.5
1.3
—
—
—
0
0
763
7188
1.05
0.61
3.8
3.9
7.57
7.95
mmol/l
1.30
647
6326
47
380
1.21
0.61
2.2
1.6
460.52
346.85
mu/l
0.88
37
312
126
1104
1.12
0.61
1.1
1.1
—
—
—
0
0
86
962
0.87
0.60
3.9
3.0
1.02
1.02
ratio
0.27
78
858
12
78
1.51
0.60
1.0
1.1
—
—
—
0
0
14
194
0.70
0.60
1.0
1.0
—
—
—
0
0
38
301
1.24
0.60
2.2
1.3
0.61
6.45
nmol/l
0.49
38
290
15
103
1.43
0.59
1.2
1.4
—
—
—
0
0
24
180
1.31
0.58
1.0
1.2
—
—
—
0
0
42
339
1.22
0.57
1.2
1.7
—
—
—
0
0
46
375
1.20
0.56
1.1
1.2
—
—
—
0
0
14
96
1.43
0.56
1.9
2.4
14.04
18.06
umol/l
1.25
14
96
54
449
1.18
0.54
1.1
1.1
—
—
—
0
0
105
1149
0.89
0.54
1.1
1.2
4.39
2.88
u/ml
0.36
65
749
17
122
1.37
0.54
3.0
3.3
9.12
10.86
mg/l
0.79
12
104
263
2750
0.93
0.53
2.0
1.8
3.32
3.50
ratio
1.36
203
2046
13
89
1.43
0.53
1.3
1.8
—
—
—
0
0
31
374
0.81
0.53
1.7
1.9
—
—
—
0
0
1088
10378
1.04
0.52
3.2
2.8
75.46
74.04
nmol/l
0.93
991
9648
19
140
1.33
0.52
1.2
1.2
—
—
—
0
0
138
1230
1.10
0.51
2.2
1.8
7.30
7.63
u/l
0.14
91
854
17
221
0.75
0.51
1.3
1.3
—
—
—
0
0
198
1797
1.09
0.50
1.2
1.3
18.00
222.13
titre
—
5
55
353
3646
0.94
0.50
1.8
1.9
—
—
—
0
0
262
2731
0.93
0.49
1.3
1.2
—
—
—
0
0
71
789
0.88
0.48
2.1
2.6
—
—
—
0
0
61
519
1.15
0.48
2.7
3.8
35.67
46.59
mg/l
0.62
49
443
57
484
1.16
0.47
2.1
1.7
12684.11
14078.45
e6/l
0.12
44
346
53
448
1.16
0.46
1.0
1.1
—
—
—
0
0
184
1680
1.08
0.43
1.6
1.5
—
—
—
0
0
27
216
1.23
0.42
1.1
1.2
105.59
114.91
pmol/l
0.43
27
216
11
77
1.40
0.41
1.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
2.0
—
—
—
0
0
10
135
0.72
0.40
1.0
1.1
—
—
—
0
0
221
2038
1.07
0.40
2.7
2.4
11.30
12.15
nmol/l
0.73
202
1862
7
101
0.68
0.39
1.9
2.3
154.00
152.99
nmol/l
—
7
90
60
520
1.13
0.39
2.7
3.8
47.11
56.52
mg/l
0.31
48
443
889
8494
1.04
0.38
3.1
2.8
—
—
—
0
0
29
237
1.20
0.38
2.3
2.1
15.61
19.42
umol/l
0.66
24
223
5
35
1.40
0.38
2.8
2.4
—
—
—
0
0
166
1738
0.93
0.38
1.5
1.6
1190.96
980.69
mu/l
1.48
138
1506
20
157
1.25
0.38
2.7
2.7
38.62
42.97
%
0.71
13
74
16
122
1.29
0.37
1.2
1.2
1060.00
934.78
titre
—
5
23
5
76
0.64
0.35
1.0
1.1
—
—
—
0
0
116
1226
0.92
0.35
1.7
1.7
—
—
—
0
0
6
43
1.37
0.34
1.2
1.2
—
—
—
0
0
30
250
1.18
0.34
6.6
3.6
23.60
25.87
umol/l
0.99
30
241
401
3783
1.04
0.33
1.3
1.3
7.00
10.37
u/ml
0.56
153
1446
168
1549
1.07
0.33
1.2
1.2
—
—
—
0
0
46
398
1.13
0.33
1.7
3.7
—
—
—
0
0
37
315
1.15
0.32
1.0
1.0
—
—
—
0
0
37
315
1.15
0.32
1.0
1.0
-2.19
-2.52
mmol/l
0.14
11
75
14
108
1.27
0.31
1.1
1.3
—
74.55
—
0
11
35
392
0.87
0.31
1.1
1.2
—
—
—
0
0
21
171
1.20
0.30
2.5
2.6
133.90
138.41
ng/l
0.07
21
151
7
53
1.29
0.30
1.0
1.1
—
—
—
0
0
7
53
1.29
0.30
1.0
1.1
—
—
—
0
0
7
53
1.29
0.30
1.0
1.1
—
—
—
0
0
44
383
1.13
0.29
1.6
1.4
18.64
19.81
u/l
0.10
34
327
228
2131
1.05
0.29
1.5
1.5
—
—
—
0
0
43
374
1.13
0.29
1.7
2.8
—
—
—
0
0
14
109
1.26
0.29
1.5
1.4
136.64
139.76
nmol/l
0.08
14
109
505
4804
1.04
0.29
1.8
1.7
—
—
—
0
0
15
118
1.25
0.29
1.0
1.0
24.87
15.87
u/ml
—
7
83
8
106
0.74
0.29
1.3
2.4
6.02
8.38
mmol/l
—
8
106
42
461
0.89
0.28
1.4
1.3
—
—
—
0
0
8
62
1.26
0.27
3.1
2.6
0.60
0.61
mmol/l
—
8
62
25
284
0.86
0.27
1.5
1.5
—
—
—
0
0
37
321
1.13
0.27
1.2
1.4
0.38
0.37
g/l
0.10
31
258
37
321
1.13
0.27
1.2
1.4
—
—
—
0
0
37
321
1.13
0.27
1.2
1.4
7.66
6.33
g/l
0.85
30
262
37
321
1.13
0.27
1.2
1.4
2.76
2.51
g/l
0.40
31
260
13
102
1.25
0.26
1.0
1.1
—
5.14
—
0
7
5
73
0.67
0.26
1.0
1.5
—
—
—
0
0
52
464
1.10
0.24
2.5
3.5
1.40
3.84
ratio
1.23
26
255
13
103
1.24
0.24
1.5
1.3
19.01
16.84
umol/l
0.23
13
93
37
324
1.12
0.24
1.0
1.0
19.31
19.53
mmol/l
0.18
37
312
32
352
0.89
0.23
1.0
1.1
10.86
17.95
u/ml
0.97
16
98
18
207
0.85
0.23
2.0
2.2
0.70
4.07
u/ml
—
5
75
5
37
1.32
0.23
1.4
1.8
1.32
1.85
ug/l
—
5
17
38
335
1.11
0.22
1.7
1.6
—
—
—
0
0
76
694
1.07
0.22
1.5
1.5
66.25
86.28
titre
—
8
78
11
132
0.82
0.21
1.0
1.2
16.36
8.38
mm/h
0.37
11
132
5
41
1.19
0.21
1.4
3.0
3.60
5.31
ug/l
—
5
41
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
4.9
—
207.70
—
0
10
0
11
0.00
0.21
0.0
1.9
—
340.36
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
85
884
0.94
0.20
1.6
1.8
—
—
—
0
0
72
753
0.93
0.20
1.1
1.1
0.62
8.19
eliau/ml
2.91
12
102
105
974
1.06
0.20
2.4
2.4
—
—
—
0
0
622
5977
1.02
0.20
2.0
2.1
—
—
—
0
0
6
47
1.25
0.20
1.3
1.1
0.69
3.49
u/ml
—
6
33
16
133
1.18
0.20
1.1
1.1
30.16
35.12
iu/ml
0.22
16
133
9
110
0.80
0.20
1.1
1.1
—
—
—
0
0
19
162
1.15
0.18
2.2
2.2
—
—
—
0
0
128
1307
0.96
0.17
1.8
1.7
352.95
308.44
mu/l
0.71
120
1186
57
522
1.07
0.17
1.6
1.5
0.47
0.33
nmol/l
0.36
47
413
30
267
1.10
0.16
3.0
3.8
0.41
0.37
e9/l
0.16
17
161
346
3312
1.03
0.16
1.7
1.6
—
—
—
0
0
8
69
1.14
0.16
1.3
1.2
—
—
—
0
0
23
250
0.90
0.15
1.2
1.3
—
221.43
—
0
7
16
137
1.14
0.15
1.1
1.3
82.44
75.07
umol/l
0.72
16
137
62
573
1.06
0.15
1.1
1.2
—
—
—
0
0
23
249
0.90
0.14
4.1
4.4
43.21
83.54
u/ml
—
7
71
23
203
1.11
0.14
1.3
1.8
—
—
—
0
0
42
383
1.07
0.14
1.0
1.1
6.65
6.85
iu/ml
—
10
76
29
260
1.09
0.14
1.2
1.2
—
—
—
0
0
23
248
0.91
0.13
1.2
1.2
5.44
16.20
u/ml
0.53
16
195
12
101
1.16
0.13
1.2
1.4
—
—
—
0
0
57
528
1.06
0.13
1.1
1.1
—
—
—
0
0
9
107
0.82
0.13
3.6
2.8
—
—
—
0
0
10
83
1.18
0.12
5.8
2.7
—
—
—
0
0
29
262
1.08
0.12
2.2
2.7
17.12
22.28
ug/l
1.31
29
257
86
872
0.96
0.10
1.6
1.7
20.97
11.59
u/ml
0.70
14
210
23
208
1.08
0.09
2.7
2.4
17.80
27.98
mg/l
1.54
15
140
28
256
1.07
0.09
2.4
1.3
—
—
nmol/l
—
0
0
19
171
1.09
0.08
1.6
1.3
192.39
220.88
pmol/l
0.18
19
171
6
55
1.07
0.08
1.3
1.1
—
—
—
0
0
6
57
1.03
0.08
2.5
1.9
—
—
—
0
0
56
570
0.96
0.08
12.5
9.5
—
—
—
0
0
7
63
1.09
0.08
1.0
1.9
41.87
41.24
g/l
—
7
63
6
71
0.83
0.07
2.2
1.8
—
—
—
0
0
8
72
1.09
0.07
7.8
5.5
5.13
8.01
%
—
8
72
8
72
1.09
0.07
3.9
2.7
55.12
43.17
%
—
8
72
7
82
0.84
0.07
1.7
3.3
—
—
—
0
0
296
2866
1.01
0.06
3.2
3.0
0.77
0.72
ug/l
0.20
182
1668
25
258
0.95
0.06
1.1
1.4
8.12
6.77
u/ml
0.11
16
169
109
1049
1.02
0.04
1.4
1.3
195.41
225.76
miu/ml
0.45
45
506
24
224
1.05
0.04
2.8
2.1
—
—
—
0
0
10
89
1.10
0.04
1.5
1.8
—
—
—
0
0
26
244
1.04
0.04
1.3
1.2
—
—
—
0
0
18
186
0.95
0.04
1.1
1.1
—
—
—
0
0
37
352
1.03
0.03
1.5
2.0
3.83
5.09
mmol/24h
1.52
31
315
549
5353
1.01
0.03
3.9
3.7
1.02
1.59
kg/l
0.80
343
3529
24
243
0.97
0.02
1.1
1.1
—
—
—
0
0
17
174
0.96
0.02
1.1
1.0
—
—
—
0
0
2063
20182
1.00
0.02
23.8
18.2
333.55
333.39
g/l
0.35
2058
20059
11
101
1.07
0.01
3.4
1.9
25.33
16.88
nmol/l
—
6
24
71
702
0.99
0.01
1.3
1.3
—
—
—
0
0
14
143
0.96
0.00
3.9
3.2
58.17
144.19
umol/l
—
6
38
50
495
0.99
0.00
1.3
1.7
0.64
0.76
g/l
0.52
40
416
10
95
1.03
0.00
3.9
2.8
0.95
1.14
umol/l
—
10
83
10
95
1.03
0.00
5.8
2.6
—
—
—
0
0
19
189
0.98
0.00
1.6
1.1
—
—
—
0
0
47
464
0.99
0.00
1.5
1.5
90.01
183.98
pmol/l
1.32
47
450
47
459
1.00
0.00
2.0
2.0
—
15.13
—
0
8
26
256
0.99
0.00
1.3
1.2
—
—
—
0
0
35
342
1.00
0.00
1.1
1.4
54.30
42.27
u/l
0.22
30
300
18
179
0.98
0.00
3.0
2.6
—
—
—
0
0
22
216
1.00
0.00
2.3
2.5
1.85
1.39
g/24h
—
10
136
40
388
1.01
0.00
3.2
2.4
137.04
111.19
ug/min
0.13
22
246
40
388
1.01
0.00
5.5
3.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
322.50
—
0
6
0
7
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
187.00
—
0
9
0
6
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
66
0.89
-0.00
1.8
7.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
1266.00
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_SEPTA_DEFEC and mortality.

Females

Parameter HR [95% CI] p-value
Q17_SEPTA_DEFEC 1.871 [1.6, 2.18] < 0.001
Birth year 0.988 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 678 out of 17245 females with Q17_SEPTA_DEFEC died.

Males

Parameter HR [95% CI] p-value
Q17_SEPTA_DEFEC 1.71 [1.44, 2.03] < 0.001
Birth year 0.981 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 575 out of 15035 males with Q17_SEPTA_DEFEC died.

Mortality risk

Mortality risk for people of age

years, who have Q17_SEPTA_DEFEC.

N-year risk Females Males
1 0.134% 0.217%
5 0.916% 1.639%
10 2.426% 4.085%
15 4.574% 7.915%
20 7.682% 12.977%

Relationships between endpoints

↥

Index endpoint: Q17_SEPTA_DEFEC – Septal defects

GWS hits: 5

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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