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Central retinal artery occlusion

DOID EFO Endpoint Browser PheWeb

H7_CENTRRETARTOCC

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H34.1
  • Hospital discharge: ICD-9 — 3623A
  • Hospital discharge: ICD-8 — 37702
  • Cause of death: ICD-10 — H34.1
  • Cause of death: ICD-9 — 3623A
  • Cause of death: ICD-8 — 37702

2 out of 7 registries used, show all original rules.

964

4. Check minimum number of events

None

964

5. Include endpoints

None

964

6. Filter based on genotype QC (FinnGen only)

847

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H34
Name in latin
Occlusio arteriae centralis retinae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6473 2574 3815
Only index persons 5023 2088 2935
Unadjusted period prevalence (%)
Whole population 0.09 0.07 0.11
Only index persons 0.10 0.08 0.11
Median age at first event (years)
Whole population 72.13 75.00 70.25
Only index persons 72.80 75.34 71.00

-FinnGen-

Key figures

All Female Male
Number of individuals 847 300 547
Unadjusted period prevalence (%) 0.20 0.11 0.25
Median age at first event (years) 71.57 71.85 71.41

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
874
Matched controls
8740
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
307.7
825
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
9.6
153.9
206
271
CKC12
NOMESCO Finland
Photocoagulation of retina
229.5
151.2
152
8
H34.8
ICD-10 Finland
Other retinal vascular occlusions
850.8
149.9
143
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
204.4
135.9
138
8
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
48.9
129.7
76
17
H43.1
ICD-10 Finland
Vitreous haemorrhage
26.7
126.9
89
37
H34.2
ICD-10 Finland
Other retinal artery occlusions
1387.5
126.3
120
*
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
11.7
118.5
130
129
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
10.2
112.2
136
155
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.0
107.7
189
332
B01AC04
ATC
clopidogrel; oral
4.0
84.7
367
1342
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
11.7
78.7
84
79
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
15.2
76.6
69
49
XCK10
NOMESCO Finland
Photography of fundus of eye
5.1
71.3
171
395
H53.9
ICD-10 Finland
Visual disturbance, unspecified
9.0
70.0
91
112
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
7.2
69.2
110
171
G45.3
ICD-10 Finland
Amaurosis fugax
10.8
66.3
74
74
AA1AD
NOMESCO Finland
CT of head and brain
3.3
65.5
459
2201
XCK00
NOMESCO Finland
Perimetry
5.4
56.5
122
255
XCH00
NOMESCO Finland
Eye pressure measurement
6.3
54.9
98
171
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
82.0
54.8
61
8
S01ED51
ATC
timolol, combinations; ophthalmic
4.3
52.7
154
412
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
5.0
52.1
123
277
H53.1
ICD-10 Finland
Subjective visual disturbances
5.2
51.7
115
246
PA6AD
NOMESCO Finland
CT of neck arteries
5.9
48.9
94
176
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
4.0
48.7
157
450
WX140
NOMESCO Finland
Parabulbar anesthesy
7.7
46.3
67
93
PAN14
NOMESCO Finland
Plastic repair of arteries internal carotid artery
15.1
43.6
39
27
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.2
43.6
215
809
C10AA05
ATC
atorvastatin; oral
2.6
40.7
522
3180
S01EC01
ATC
acetazolamide; systemic
7.6
36.4
53
74
XCD20
NOMESCO Finland
Photoangiography of eye
55.0
35.7
42
8
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.9
35.2
210
869
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.0
35.0
191
753
3623A
ICD-9 Finland
Other retinal disorders, Retinal vascular occlusion[OCCLUSIO ARTERIAE CENTRALIS RETINAE]
+∞
33.6
32
*
H53.4
ICD-10 Finland
Visual field defects
6.5
30.4
51
83
CS494
NOMESCO Finland
Other visual field testing
6.2
30.3
53
90
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.7
29.6
195
843
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
50.4
28.6
34
7
H54.4
ICD-10 Finland
Blindness, monocular
80.4
27.9
31
*
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.3
27.1
73
181
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.9
25.3
57
122
C10AA01
ATC
simvastatin; oral
2.1
24.8
519
3582
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
25.2
24.5
34
14
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
5.7
24.4
46
84
H33.0
ICD-10 Finland
Retinal detachment with retinal break
+∞
23.0
22
*
H3600, E113,
ICD-10 Finland
+∞
23.0
22
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.1
22.9
344
2085
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.1
22.9
369
2295
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
22.6
234
1227
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
8.1
22.3
30
38
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
22.1
511
3597
37702
ICD-8 Finland
Other diseases of retina and optic nerve, Embolia, spasmus arteriae centralis retinae
+∞
22.0
21
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.6
21.9
142
603
CKC10
NOMESCO Finland
Local photocoagulation of retina
82.3
21.8
24
*
S01EA05
ATC
brimonidine; ophthalmic
4.7
21.7
51
113
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.7
21.7
129
524
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
5.5
21.1
41
77
CKC20
NOMESCO Finland
Cryopexy of undetached retina
+∞
20.9
20
*
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
3.7
20.7
69
199
I10
ICD-10 Finland
Essential (primary) hypertension
2.1
19.8
651
5092
H33.3
ICD-10 Finland
Retinal breaks without detachment
107.5
19.6
21
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
22.2
19.6
28
13
S01EE01
ATC
latanoprost; ophthalmic
2.9
19.5
99
369
114
Kela drug reimbursment
Glaucoma
2.6
19.3
129
554
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.0
19.1
296
1789
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.6
19.0
120
501
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.0
19.0
91
329
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.4
18.9
141
638
H3603, E113,
ICD-10 Finland
+∞
18.8
18
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.4
18.4
149
699
C03CA01
ATC
furosemide; systemic
1.9
18.4
433
2998
H26.4
ICD-10 Finland
After-cataract
2.5
17.9
131
586
XCW10
NOMESCO Finland
Assessment of vision
7.4
17.9
26
36
C08CA01
ATC
amlodipine; oral
1.9
17.8
430
2991
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.9
17.8
403
2747
H3603, E103,
ICD-10 Finland
+∞
17.8
17
*
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.9
17.6
284
1733
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.6
17.4
111
465
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
15.2
17.2
28
19
H54.6
ICD-10 Finland
Moderate visual impairment, monocular
64.6
16.8
19
*
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
+∞
16.7
16
*
I50.9
ICD-10 Finland
Heart failure, unspecified
2.0
16.6
242
1421
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.5
16.5
109
465
S01EC54
ATC
brinzolamide, combinations; ophthalmic
6.3
16.5
28
46
AN1
HP
Coronary angiography
2.2
16.3
168
868
F05
ICPC
Visual disturbance other
4.1
16.3
46
118
C10AX09
ATC
ezetimibe; oral
2.1
16.2
181
965
B01AC07
ATC
dipyridamole; systemic
2.7
16.1
93
371
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.3
15.7
60
189
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
4.0
15.7
46
121
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.8
15.7
82
310
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
+∞
15.7
15
*
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
+∞
15.7
15
*
H3601, E113,
ICD-10 Finland
+∞
15.7
15
*
H25.1
ICD-10 Finland
Senile nuclear cataract
1.8
15.6
351
2360
H36.00
ICD-10 Finland
Diabetic background retinopathy
162.8
15.5
16
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
15.4
262
1613
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
13.4
15.2
26
20
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.2
15.2
137
670
C09AA05
ATC
ramipril; oral
1.8
14.9
302
1963
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
14.8
109
488
H34.0
ICD-10 Finland
Transient retinal artery occlusion
+∞
14.6
14
*
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
81.5
14.6
16
*
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
152.5
14.5
15
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.9
14.3
70
256
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
4.8
14.1
32
69
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.7
14.1
82
328
A10AA01, ,
ATC
6.0
14.1
25
43
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.8
14.0
326
2197
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.9
13.9
245
1518
205
Kela drug reimbursment
Chronic hypertension
1.8
13.9
341
2333
I50.0
ICD-10 Finland
Congestive heart failure
2.2
13.7
131
654
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
13.6
13
*
C07AB07
ATC
bisoprolol; oral
1.7
13.6
526
4076
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
142.1
13.5
14
*
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.0
13.5
39
102
FME20
NOMESCO Finland
Transvenous aortic valve replacement via femoral artery
4.7
13.1
30
65
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.0
13.1
161
883
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.8
13.0
266
1719
B01AA03
ATC
warfarin; systemic
1.8
13.0
277
1814
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
12.9
161
889
S01ED01
ATC
timolol; ophthalmic
3.2
12.9
52
170
CKC15
NOMESCO Finland
Panretinal photocoagulation
32.5
12.6
16
5
A10AB05
ATC
insulin aspart; parenteral
2.5
12.6
80
334
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
131.8
12.5
13
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.3
12.3
32
77
H54.5
ICD-10 Finland
Severe visual impairment, monocular
14.6
12.3
20
14
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
14.6
12.3
20
14
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
3.4
12.0
43
130
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.3
11.9
91
413
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
3.0
11.9
52
178
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
47.3
11.9
14
*
C08CA13
ATC
lercanidipine; oral
1.9
11.8
163
930
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.4
11.6
29
68
H3600, E103,
ICD-10 Finland
+∞
11.5
11
*
T90
ICPC
Diabetes non-insulin dependent
1.7
11.5
246
1604
CKD40
NOMESCO Finland
Endophotocoagulation of retina
121.6
11.5
12
*
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
121.6
11.5
12
*
S01EC04
ATC
brinzolamide; ophthalmic
2.9
11.4
55
199
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.3
11.3
87
396
PAW37
NOMESCO Finland
Biopsy of temporal artery
10.7
11.3
21
20
L28
ICPC
Limited function/disability (L)
1.8
11.2
223
1423
H54.1
ICD-10 Finland
Severe visual impairment, binocular
43.9
10.9
13
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
10.9
213
1350
H35.37
ICD-10 Finland
Macular holes
60.8
10.6
12
*
A10AA02, ,
ATC
3.6
10.6
34
96
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
10.5
279
1918
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
10.2
10.5
20
20
C01DA14
ATC
isosorbide mononitrate; oral
1.7
10.5
234
1536
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
4.2
10.5
28
69
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
10.4
10
*
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
32.9
10.3
13
*
ZXA05
NOMESCO Finland
Left side
1.7
10.3
236
1559
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
10.3
360
2651
H25.0
ICD-10 Finland
Senile incipient cataract
2.4
10.2
71
309
A10AE04
ATC
insulin glargine; parenteral
2.1
10.0
95
472
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
26.3
9.8
13
5
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
9.8
144
836
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
7.5
9.7
22
30
I25.2
ICD-10 Finland
Old myocardial infarction
2.0
9.7
108
569
PE1AT
NOMESCO Finland
Femoral artery PTA
4.3
9.7
25
60
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.4
9.6
70
311
H40.0
ICD-10 Finland
Glaucoma suspect
2.2
9.6
80
377
C03DA01
ATC
spironolactone; oral
1.8
9.6
150
887
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
4.1
9.6
26
65
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
9.5
262
1811
C07AB02
ATC
metoprolol; systemic
1.7
9.5
234
1573
N02BE01
ATC
paracetamol; systemic, rectal
1.9
9.5
747
6644
PD5BD
NOMESCO Finland
Extensive CT of aorta
3.5
9.4
32
94
H3601, E103,
ICD-10 Finland
+∞
9.4
9
*
H33.5
ICD-10 Finland
Other retinal detachments
22.0
9.4
13
6
PD5AD
NOMESCO Finland
CT of aorta
3.2
9.3
37
120
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.3
9.3
34
105
280
Kela drug reimbursment
Clopidogrel
3.5
9.2
32
95
I20.09
ICD-10 Finland
Unstable angina
2.2
9.2
83
404
A10AC01
ATC
insulin (human); parenteral
2.3
9.2
74
344
S01EE04
ATC
travoprost; ophthalmic
3.7
9.2
29
81
M04AA01
ATC
allopurinol; systemic
1.7
9.1
176
1105
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.3
9.1
74
345
ZXD05
NOMESCO Finland
Urgent procedure
1.6
9.1
265
1854
S01EA03
ATC
apraclonidine; ophthalmic
8.4
9.1
19
23
H02AB06
ATC
prednisolone; systemic
1.5
9.1
415
3221
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
9.0
273
1927
M48.0
ICD-10 Finland
Spinal stenosis
1.8
9.0
141
832
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
9.0
241
1653
S97
ICPC
Chronic ulcer skin
2.2
9.0
80
388
C02AC05
ATC
moxonidine; oral
2.4
8.9
62
270
H47.2
ICD-10 Finland
Optic atrophy
12.7
8.9
15
12
PE1YT
NOMESCO Finland
Femoral or popliteal artery PTA with stent
4.7
8.9
20
43
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
4.7
8.9
20
43
AA1
HP
Conventional CABG
3.1
8.8
37
124
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.1
8.8
88
446
A10AB01
ATC
insulin (human); parenteral
3.7
8.8
27
74
F01
ICPC
Eye pain
3.7
8.8
27
74
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
2.7
8.7
47
181
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.3
8.7
32
99
S18
ICPC
Laceration/cut
1.5
8.7
404
3139
A10AE05
ATC
insulin detemir; parenteral
2.5
8.6
52
212
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.7
8.6
27
75
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
8.5
270
1922
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
3.6
8.5
27
76
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
4.4
8.4
21
49
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
90.9
8.4
9
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.4
8.4
60
265
K65.0
ICD-10 Finland
Acute peritonitis
4.9
8.4
18
37
H35.36
ICD-10 Finland
Macular cyst
+∞
8.3
8
*
F28
ICPC
Limited function/disability (F)
10.2
8.0
15
15
H57.1
ICD-10 Finland
Ocular pain
3.3
8.0
29
89
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.3
8.0
29
89
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
8.0
256
1824
81
HP
Angiography of the heart and coronary arteries
2.0
7.9
94
507
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
4.7
7.9
18
39
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
13.2
7.9
13
10
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.5
7.8
289
2123
A02BC02
ATC
pantoprazole; systemic
1.5
7.8
568
4803
A46
ICD-10 Finland
Erysipelas
1.7
7.8
157
995
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
7.0
7.8
18
26
R42
ICD-10 Finland
Dizziness and giddiness
1.6
7.8
215
1479
H36.01
ICD-10 Finland
Diabetic maculopathy
45.4
7.7
9
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
7.5
7.7
17
23
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.2
7.6
30
97
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
18.5
7.6
11
6
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
7.6
124
740
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
3.5
7.6
25
72
Z3229
NOMESCO Finland
Other healthcare associate professional
2.0
7.6
82
428
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.8
7.5
111
643
S01EC03
ATC
dorzolamide; ophthalmic
3.6
7.5
24
68
J01DB01
ATC
cefalexin; oral
1.6
7.5
650
5684
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.6
7.4
42
166
SPAT1263
SPAT
Sampling
1.5
7.4
338
2590
TPX22
NOMESCO Finland
Intravenous arterial thrombolysis
6.0
7.4
19
32
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
13.5
7.4
12
9
R4120
NOMESCO Finland
Occupational therapy
2.2
7.4
61
287
A10BK03
ATC
empagliflozin; oral
1.9
7.3
97
542
ZX198
NOMESCO Finland
Other local administration
11.0
7.3
13
12
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.4
7.3
25
74
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
7.3
298
2232
B03XA02
ATC
darbepoetin alfa; parenteral
3.1
7.3
30
100
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
7.3
311
2351
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
7.2
116
689
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
7.2
304
2290
FNC20
NOMESCO Finland
Aorto-coronary venous bypass with two distal anastomoses
2.8
7.2
35
128
UJF32
NOMESCO Finland
Coloscopy
1.6
7.2
234
1667
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.4
7.1
49
213
K90
ICPC
Stroke/cerebrovascular accident
2.5
7.1
44
182
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
7.1
93
518
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.4
7.0
48
208
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.7
7.0
140
886
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.0
6.9
71
363
127
Kela drug reimbursment
Transplant complication
5.5
6.9
19
35
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
7.6
6.9
15
20
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.2
6.9
54
249
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
8.3
6.8
14
17
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
4.2
6.8
18
44
F29
ICPC
Eye symptom/complaint other
1.9
6.8
84
459
J01FF01
ATC
clindamycin; systemic
1.5
6.8
218
1546
A10BA02
ATC
metformin; oral
1.5
6.8
274
2041
H35.4
ICD-10 Finland
Peripheral retinal degeneration
40.4
6.8
8
*
I74.3
ICD-10 Finland
Embolism and thrombosis of arteries of lower extremities
3.9
6.7
19
49
N19
ICD-10 Finland
Unspecified kidney failure
2.2
6.7
55
258
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
6.7
259
1911
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
6.7
503
4220
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
6.6
124
770
C09AA02
ATC
enalapril; systemic
1.5
6.6
210
1485
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
3.3
6.6
24
74
N07BA03
ATC
varenicline; oral
2.9
6.6
30
106
K29
ICPC
Cardiovascular sympt/complt other
2.3
6.5
50
228
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
70.3
6.4
7
*
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
70.3
6.4
7
*
EBA00
NOMESCO Finland
Extraction of tooth
1.5
6.4
256
1898
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
6.4
106
636
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.4
6.4
44
192
C10AA02
ATC
lovastatin; oral
2.2
6.4
55
264
C08CA05
ATC
nifedipine; systemic
1.9
6.3
75
404
A10BH05
ATC
linagliptin; oral
2.1
6.3
62
312
ZXA10
NOMESCO Finland
Bilateral
1.6
6.3
163
1098
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
6.3
79
434
WX199
NOMESCO Finland
Other local analgesia
2.4
6.3
40
168
B01AB05
ATC
enoxaparin; parenteral
1.5
6.3
277
2095
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
+∞
6.3
6
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
6.3
6
*
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
6.3
6
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
6.3
250
1853
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.1
6.2
61
307
XF600
NOMESCO Finland
Bloodpressure measurement
2.0
6.2
63
321
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
26.9
6.2
8
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.8
6.2
86
488
S01EE03
ATC
bimatoprost; ophthalmic
2.8
6.2
29
104
L03.9
ICD-10 Finland
Cellulitis, unspecified
3.4
6.2
21
62
Z13.1
ICD-10 Finland
Special screening examination for diabetes mellitus
3.3
6.2
22
67
WX002
NOMESCO Finland
Sedation and analgesia
1.6
6.1
161
1088
L04AA06
ATC
mycophenolic acid; systemic
3.8
6.1
18
48
ZXA00
NOMESCO Finland
Right side
1.5
6.1
234
1719
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
6.1
184
1286
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.2
6.0
23
73
C08CA02
ATC
felodipine; oral
1.7
6.0
108
662
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.1
6.0
15
25
AN3
HP
Balloon angioplasty and metallic stent
2.4
6.0
41
178
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
2.5
6.0
35
141
PEH56
NOMESCO Finland
Bypass from femoral to popliteal artery above knee
3.9
6.0
17
44

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
473
2478
2.98
54.88
2.7
2.2
150.79
253.74
u/l
2.19
462
2344
308
1352
2.97
48.18
2.2
1.9
30.56
29.81
s
1.16
302
1313
589
4024
2.42
32.50
27.9
19.6
1.42
1.37
inr
0.99
519
3400
624
4555
2.29
26.78
8.7
5.3
7.03
6.82
mmol/l
1.86
615
4358
174
789
2.50
23.51
2.6
2.6
4.89
6.73
ug/l
1.13
152
682
541
4039
1.89
17.93
9.7
9.1
4.64
4.35
e9/l
1.94
475
3480
378
2524
1.88
17.81
3.2
2.6
—
—
—
0
0
453
3220
1.84
17.32
6.6
4.5
42.38
92.44
ng/l
1.20
394
2570
474
3419
1.84
17.26
3.6
3.0
—
—
estimate
—
0
0
415
2885
1.83
16.93
4.5
3.5
2876.39
1915.15
ng/l
1.88
386
2520
487
3570
1.82
16.55
6.9
5.7
0.64
0.63
e9/l
0.55
420
3011
183
974
2.11
16.46
4.9
3.6
7.37
7.38
ph
1.36
119
584
487
3587
1.81
16.12
7.0
5.7
0.04
0.04
e9/l
0.59
419
3032
206
1159
2.02
15.89
10.3
5.5
1.09
1.03
mmol/l
2.12
196
1059
490
3633
1.79
15.69
7.1
5.8
1.62
1.79
e9/l
3.51
430
3154
535
4074
1.81
15.63
12.1
7.5
1.20
1.21
mmol/l
2.60
469
3472
494
3692
1.78
15.20
7.4
5.9
0.21
0.20
e9/l
0.61
428
3184
300
1936
1.84
15.19
5.0
4.3
82.13
83.38
%
0.31
300
1904
69
244
2.98
14.92
2.1
2.0
20.81
21.38
s
0.35
58
229
173
941
2.05
14.54
5.5
3.5
1.68
2.03
mmol/l
0.70
144
801
525
4024
1.76
14.50
6.8
6.7
12.55
12.44
umol/l
0.06
509
3839
482
3610
1.75
14.40
6.0
5.2
34.16
34.54
g/l
0.75
446
3357
151
789
2.10
14.10
12.7
8.5
—
—
—
0
0
293
1913
1.80
14.07
3.1
2.5
—
—
—
0
0
456
3379
1.73
14.01
7.1
6.0
23.28
25.43
%
4.11
438
3182
449
3318
1.73
13.89
6.9
5.8
60.81
58.98
%
2.58
433
3135
31
66
4.83
13.86
1.3
1.3
4.54
8.41
u/ml
0.47
13
27
196
1134
1.94
13.75
9.5
7.3
4.99
5.09
kpa
0.74
190
1084
196
1135
1.94
13.71
9.5
7.3
12.17
11.88
kpa
0.29
190
1086
488
3708
1.72
13.48
11.9
6.8
1.20
1.21
mmol/l
2.50
462
3398
449
3337
1.71
13.44
7.3
6.0
9.43
9.16
%
0.95
429
3103
194
1127
1.93
13.41
9.4
7.4
0.29
1.08
mmol/l
1.65
157
912
448
3331
1.71
13.36
7.2
5.9
3.08
2.82
%
0.96
425
3095
369
2605
1.72
13.30
4.1
3.4
68.41
50.62
mg/l
0.77
271
1749
105
485
2.32
13.26
1.8
1.8
1.56
1.51
g/l
0.22
93
426
124
614
2.19
13.25
11.9
9.0
1.42
1.30
%
0.71
124
609
194
1133
1.92
13.18
9.6
7.4
7.42
7.41
ph
0.07
102
665
447
3333
1.70
13.10
7.3
6.0
0.69
0.63
%
1.61
425
3101
223
1375
1.83
12.73
4.2
2.7
2.23
2.21
g/l
0.22
210
1256
155
848
2.01
12.70
13.2
6.5
13.54
11.62
mmol/l
2.49
149
808
369
2631
1.70
12.65
4.1
3.3
6.45
7.46
mmol/l
6.21
316
2193
374
2684
1.69
12.46
4.8
4.1
14.75
8.60
mg/mmol
1.21
270
1735
368
2651
1.67
11.94
5.3
4.5
—
—
—
0
0
232
1481
1.77
11.67
4.3
2.7
9.85
11.96
umol/l
6.54
218
1372
209
1295
1.81
11.62
4.4
2.7
18.17
21.91
%
5.32
198
1196
189
1143
1.83
11.35
3.0
2.5
1.97
1.78
%
1.73
171
1019
26
57
4.67
11.24
1.1
1.3
—
—
—
0
0
320
2260
1.66
10.99
3.1
2.3
3.21
3.01
mg/l
0.77
282
1924
217
1385
1.75
10.82
3.8
3.2
0.82
0.81
mmol/l
0.52
208
1292
330
2361
1.64
10.70
3.5
2.6
66.22
94.51
u/l
0.38
315
2168
22
44
5.10
10.56
2.2
2.3
—
—
—
0
0
154
898
1.87
10.32
2.1
1.8
—
—
—
0
0
152
884
1.87
10.26
3.4
2.5
74.03
66.31
e9/l
1.81
114
664
137
798
1.85
9.15
3.8
3.0
66.92
65.96
g/l
0.78
124
727
638
5454
1.63
9.14
10.7
8.5
85.69
82.16
u/l
0.91
609
5131
335
2487
1.56
8.90
7.3
5.7
—
—
—
0
0
736
6548
1.79
8.89
31.7
20.2
28.02
29.12
mg/l
0.41
674
5623
400
3090
1.54
8.88
4.8
3.1
159.68
153.28
ug/l
0.23
371
2807
223
1503
1.65
8.87
1.9
1.7
1.42
1.63
mg/l
0.56
187
1208
582
4899
1.56
8.61
6.4
5.4
2138.36
1785.03
e6/l
0.07
14
89
69
322
2.24
8.49
1.3
1.4
—
14.03
—
0
6
60
267
2.34
8.25
1.1
1.2
—
—
—
0
0
492
4018
1.51
8.16
3.9
3.4
57.08
55.73
u/l
0.11
466
3711
97
528
1.94
7.95
7.6
3.6
24.00
24.43
mmol/l
0.62
97
521
276
2008
1.55
7.81
4.0
3.0
372.92
364.42
umol/l
0.66
244
1703
66
314
2.19
7.76
4.8
3.3
1.70
4.02
ratio
0.97
39
182
70
345
2.12
7.53
4.7
3.4
56.48
71.08
mg/l
0.35
57
293
447
3618
1.48
7.49
2.5
2.3
91.19
92.94
pmol/l
0.33
251
1945
70
346
2.11
7.48
4.7
3.4
51.52
79.88
mg/l
0.36
56
294
321
2432
1.51
7.45
8.0
4.3
7.39
7.40
ph
0.82
241
1785
299
2232
1.52
7.45
3.3
3.2
28.53
34.93
u/l
3.54
287
2094
106
610
1.84
7.32
3.9
3.1
124.02
125.86
g/l
0.33
106
590
81
432
1.96
7.04
1.8
1.8
3.92
1.86
ug/l
0.70
72
369
327
2517
1.48
6.89
1.9
1.8
18.48
19.69
nmol/l
0.79
281
2107
332
2565
1.47
6.86
3.6
3.6
—
—
—
0
0
375
2971
1.46
6.79
5.5
4.4
99.39
123.70
e6/l
0.28
286
2203
27
89
3.10
6.66
2.4
2.4
—
—
—
0
0
347
2717
1.46
6.64
4.5
3.8
260.41
98.18
e6/l
0.49
281
2144
174
1181
1.59
6.54
2.4
2.1
—
—
—
0
0
125
784
1.69
6.41
1.3
1.3
1030.30
437.60
titre
1.33
33
183
667
5945
1.51
6.26
5.4
4.5
1.29
1.25
mmol/l
0.82
629
5297
745
6808
1.64
6.25
39.5
25.1
4.04
4.02
mmol/l
1.03
732
6654
107
648
1.74
6.23
5.4
4.0
111.11
100.57
ng/l
0.41
95
561
260
1950
1.47
6.11
3.4
2.9
4.03
4.47
e6/l
0.45
236
1774
23
73
3.21
6.05
1.1
1.2
—
—
—
0
0
743
6803
1.61
5.97
39.1
24.9
139.04
139.57
mmol/l
4.86
732
6657
224
1638
1.49
5.95
6.3
4.4
588.57
843.22
ng/l
0.19
196
1425
228
1678
1.49
5.85
1.9
1.8
1155.97
1150.92
nmol/l
0.03
180
1254
26
91
2.91
5.82
2.0
2.6
0.83
1.73
g/24h
0.68
19
53
48
229
2.16
5.66
1.5
1.8
3.60
8.10
iu/ml
1.20
11
63
370
3001
1.40
5.56
4.7
3.8
6.36
6.27
ph
0.79
196
1648
688
6230
1.49
5.43
6.3
5.3
3.95
4.36
mmol/l
21.65
662
5668
747
6884
1.59
5.43
40.1
27.1
101.14
86.46
umol/l
5.81
736
6771
683
6179
1.48
5.39
6.2
5.2
1.32
1.42
mmol/l
8.57
652
5567
85
504
1.76
5.33
4.3
2.6
0.61
0.62
%
0.09
85
499
339
2727
1.40
5.27
3.1
3.5
2.35
2.35
mmol/l
0.09
304
2435
749
6931
1.56
5.07
45.1
30.2
7.25
7.00
e9/l
2.38
726
6728
98
616
1.67
4.98
4.2
4.5
—
—
—
0
0
748
6927
1.55
4.97
45.1
30.2
234.33
236.83
e9/l
0.45
733
6753
748
6928
1.55
4.95
45.0
30.1
92.12
92.01
fl
0.25
737
6817
748
6929
1.55
4.94
46.5
30.8
38.60
39.48
%
3.57
736
6811
748
6929
1.55
4.94
44.9
30.1
30.45
30.51
pg
0.36
737
6817
748
6929
1.55
4.94
45.1
30.2
4.29
4.37
e12/l
3.12
726
6727
748
6929
1.55
4.94
45.5
30.4
128.81
132.00
g/l
5.81
739
6819
662
5992
1.43
4.86
5.6
5.1
2.34
2.07
mu/l
0.93
616
5395
22
78
2.87
4.84
2.5
2.4
586.45
1070.38
mg
0.78
22
78
447
3805
1.36
4.73
5.3
4.3
0.01
0.38
estimate
0.48
87
798
93
586
1.66
4.69
4.8
3.9
7.42
7.41
ph
0.22
81
479
730
6749
1.50
4.64
16.6
12.8
23.94
24.63
u/l
0.63
714
6499
219
1665
1.42
4.61
5.6
4.6
1.02
1.02
kg/l
0.07
149
1138
696
6379
1.45
4.59
7.3
6.2
2.14
2.50
mmol/l
24.03
669
5765
445
3798
1.35
4.57
5.3
4.3
0.00
3.79
estimate
0.80
98
849
119
807
1.55
4.43
3.4
3.3
279.46
254.92
ng/l
0.26
112
751
572
5090
1.36
4.37
39.0
26.8
329.82
331.23
g/l
2.94
564
5051
678
6207
1.41
4.31
9.7
7.1
42.33
40.11
mmol/mol
7.18
641
5668
125
863
1.52
4.29
2.8
2.7
10.70
9.15
umol/l
0.24
111
769
60
344
1.80
4.25
3.3
2.6
10.26
10.88
g/l
0.47
51
304
56
315
1.83
4.22
3.5
3.0
24.29
24.75
mmol/l
0.34
56
307
436
3739
1.33
4.21
5.2
4.3
0.00
0.00
estimate
-0.00
94
825
552
4900
1.34
4.20
4.1
4.0
15.35
15.12
pmol/l
1.27
508
4380
137
972
1.49
4.13
1.2
1.3
—
—
—
0
0
57
330
1.78
3.92
1.3
1.2
—
—
—
0
0
97
650
1.55
3.82
2.2
1.5
—
—
—
0
0
287
2347
1.33
3.74
4.4
3.7
0.65
0.46
e6/l
0.58
220
1782
183
1395
1.39
3.73
5.4
4.6
—
—
—
0
0
40
210
1.95
3.73
2.5
3.3
9.29
7.54
mmol/l
0.96
40
203
364
3080
1.31
3.72
17.1
12.3
0.00
0.00
e9/l
0.18
289
2496
14
45
3.15
3.66
1.4
1.5
—
—
—
0
0
95
641
1.54
3.63
4.3
3.4
—
—
—
0
0
329
2754
1.31
3.61
5.3
4.1
—
0.73
—
0
11
97
659
1.53
3.60
4.5
4.2
1.56
0.86
%
0.91
27
233
705
6559
1.39
3.57
26.9
18.4
—
—
—
0
0
24
105
2.32
3.55
1.5
1.1
—
—
—
0
0
35
182
1.96
3.38
2.9
2.4
134.74
86.89
ug/min
0.38
23
109
92
628
1.52
3.35
4.2
4.0
1.50
0.70
%
0.85
26
223
91
620
1.52
3.34
4.6
4.2
0.09
0.14
%
0.34
23
195
154
1163
1.39
3.31
1.7
1.5
2.82
2.73
g/l
0.16
86
650
93
640
1.51
3.26
4.4
4.4
0.13
0.16
%
0.15
24
196
105
741
1.47
3.26
2.1
1.5
—
—
—
0
0
680
6320
1.34
3.23
6.6
5.7
6.29
6.08
mmol/l
3.11
631
5663
265
2183
1.31
3.20
5.4
4.4
0.00
0.00
estimate
0.50
81
733
60
375
1.64
3.18
1.6
1.4
—
—
—
0
0
93
644
1.50
3.17
2.1
2.0
373.39
394.25
nmol/l
0.52
83
584
361
3105
1.28
3.10
2.8
2.3
77.72
79.66
nmol/l
0.68
327
2712
42
241
1.78
3.03
2.5
3.2
1.58
1.64
mmol/l
0.26
42
233
64
417
1.58
2.89
5.0
4.1
—
—
—
0
0
82
565
1.50
2.88
2.3
1.5
—
—
—
0
0
254
2107
1.29
2.87
8.9
6.5
—
—
—
0
0
106
773
1.42
2.79
5.9
4.5
7.35
7.36
ph
0.22
80
547
65
431
1.55
2.73
2.8
1.8
2.33
1.56
g/l
0.53
59
384
13
48
2.73
2.72
1.2
1.1
—
—
—
0
0
6
10
6.03
2.70
1.2
1.0
—
—
—
0
0
34
190
1.82
2.70
2.1
2.8
34.88
34.83
umol/l
0.00
34
164
311
2664
1.26
2.67
2.4
2.4
—
—
—
0
0
37
213
1.77
2.67
1.5
1.6
—
—
—
0
0
67
451
1.53
2.64
1.2
1.2
—
—
—
0
0
7
15
4.70
2.60
1.4
1.8
—
—
—
0
0
9
225
0.39
2.58
1.2
1.5
—
—
—
0
0
24
123
1.98
2.47
3.5
1.4
0.98
0.85
nmol/l
0.46
18
100
103
766
1.39
2.44
1.4
1.3
—
—
—
0
0
324
2813
1.24
2.43
5.4
4.4
0.01
0.07
estimate
0.85
81
672
180
1463
1.29
2.35
3.9
3.3
1.41
1.25
e6/l
0.14
107
821
39
239
1.66
2.29
4.9
2.6
58.25
59.79
%
0.14
39
232
208
1727
1.27
2.29
2.6
3.1
2.47
2.46
mmol/l
0.54
181
1528
6
13
4.64
2.27
1.2
1.0
—
—
—
0
0
120
926
1.34
2.27
3.0
4.1
5.52
16.88
ug/l
1.42
104
785
36
219
1.67
2.18
4.8
3.7
2.05
1.56
index
0.16
21
117
48
315
1.55
2.16
5.7
4.5
24.35
25.14
mmol/l
1.04
42
281
158
1280
1.29
2.11
1.3
1.2
1.80
1.46
u/ml
0.18
28
311
31
184
1.71
2.07
1.5
1.1
—
—
—
0
0
75
545
1.41
2.06
3.2
2.9
11.54
11.12
g/l
0.25
69
485
8
26
3.10
2.01
1.0
1.0
—
—
—
0
0
9
32
2.83
2.00
1.0
1.0
—
—
—
0
0
30
179
1.70
1.97
1.6
1.3
73.50
62.55
mmol/l
0.67
24
146
35
218
1.63
1.97
22.7
12.4
—
—
—
0
0
7
21
3.35
1.97
1.0
1.1
—
—
—
0
0
92
699
1.35
1.94
3.3
2.5
47.22
34.69
u/l
0.96
78
586
5
11
4.56
1.94
1.0
1.0
—
—
—
0
0
5
11
4.56
1.94
1.0
1.0
—
—
—
0
0
6
16
3.77
1.93
29.3
8.4
4.62
5.29
kpa
—
6
16
20
106
1.91
1.92
1.5
1.4
—
—
—
0
0
5
12
4.18
1.82
8.2
12.0
5.42
5.55
mmol/l
—
5
12
18
94
1.93
1.81
2.0
1.4
138.00
177.19
au/ml
—
6
23
8
29
2.77
1.79
1.6
2.4
1816.38
1211.83
u/ml
—
8
29
11
47
2.36
1.78
1.0
1.2
187.82
136.14
nmol/l
1.42
11
47
165
1373
1.25
1.77
4.3
3.4
2.06
1.80
e6/l
0.19
94
729
126
1024
1.27
1.66
1.3
1.3
50.61
35.74
iu/ml
0.23
34
320
207
1784
1.21
1.59
1.4
1.3
—
—
—
0
0
5
15
3.35
1.52
1.0
1.2
25.20
27.87
s
—
5
15
7
27
2.61
1.51
1.0
3.0
—
—
—
0
0
13
65
2.02
1.49
3.2
3.6
11.69
35.30
mg/l
—
8
52
201
1740
1.20
1.47
1.9
1.8
62500392.01
436.19
pmol/l
0.50
168
1411
10
45
2.24
1.46
1.0
1.2
—
—
—
0
0
30
196
1.55
1.44
4.1
4.4
—
—
—
0
0
29
190
1.54
1.39
4.0
5.2
2.95
2.54
mmol/l
0.33
15
129
14
247
0.56
1.36
1.1
1.2
—
—
—
0
0
17
97
1.77
1.35
2.9
2.3
-0.59
0.23
mmol/l
0.38
17
92
33
224
1.49
1.35
1.4
1.5
240.35
270.59
ug/g
0.43
17
142
100
812
1.26
1.35
2.7
3.3
4.59
4.73
e9/l
0.13
83
675
118
978
1.24
1.34
1.2
1.3
17.92
16.12
u/ml
0.07
45
337
13
68
1.93
1.34
1.4
1.4
—
—
nmol/l
—
0
0
32
217
1.49
1.32
1.4
1.6
13548.87
19472.00
e6/l
0.66
23
156
373
3427
1.15
1.30
5.4
6.2
4.76
4.78
ug/l
0.00
329
3032
55
417
1.34
1.24
2.7
2.5
—
—
—
0
0
18
108
1.68
1.23
1.3
1.1
—
—
—
0
0
84
679
1.26
1.20
1.8
2.2
256.87
171.11
ug/g
0.44
60
543
6
26
2.32
1.19
1.3
2.0
0.66
0.59
mmol/l
—
6
26
8
38
2.12
1.18
1.9
1.7
72.50
92.74
umol/l
—
8
38
211
1871
1.17
1.17
3.8
3.3
0.00
0.08
—
8
62
5
20
2.51
1.15
1.2
1.9
2.00
1.14
nmol/l
—
5
15
105
876
1.23
1.14
1.4
1.5
—
—
—
0
0
54
417
1.31
1.10
3.5
3.9
1.02
1.02
ratio
0.42
49
382
193
1709
1.17
1.09
3.8
3.2
502.53
545.27
mosm/kgh2o
2.45
173
1495
80
653
1.25
1.07
11.4
4.0
1.21
1.22
mmol/l
0.95
74
567
24
162
1.50
1.05
1.7
1.5
—
—
—
0
0
5
22
2.28
1.03
1.2
1.3
—
—
—
0
0
9
47
1.92
1.02
2.0
1.6
119.50
102.76
ng/l
—
9
47
83
690
1.22
0.96
2.3
2.2
0.00
0.00
estimate
-0.00
12
124
0
32
0.00
0.95
0.0
1.1
—
0.08
—
0
10
68
554
1.25
0.94
2.7
3.0
5.98
6.05
ph
0.24
48
400
16
101
1.60
0.94
1.3
1.2
215.18
312.47
u/ml
0.47
11
53
25
175
1.44
0.93
1.1
1.1
—
—
—
0
0
55
440
1.27
0.90
2.7
3.0
—
—
—
0
0
6
29
2.08
0.89
1.0
1.2
—
—
—
0
0
12
71
1.70
0.89
1.5
2.7
8.63
8.12
mmol/l
0.26
12
71
12
72
1.68
0.85
1.3
1.3
—
—
—
0
0
12
72
1.68
0.85
1.3
1.3
—
—
—
0
0
32
240
1.35
0.83
1.4
1.5
—
—
—
0
0
112
973
1.17
0.83
1.5
1.4
—
—
—
0
0
38
293
1.31
0.83
4.7
3.0
223.16
480.91
mg/l
0.62
19
117
91
779
1.19
0.80
2.2
2.3
0.18
0.20
g/l
1.13
86
716
0
28
0.00
0.76
0.0
1.3
—
—
—
0
0
28
210
1.34
0.74
2.5
2.3
125.35
126.62
g/l
0.08
20
163
14
92
1.53
0.72
3.3
2.5
—
—
—
0
0
7
39
1.80
0.72
1.3
1.4
—
—
—
0
0
5
26
1.93
0.70
2.4
2.4
—
—
—
0
0
15
101
1.49
0.70
1.4
1.3
—
—
—
0
0
13
85
1.54
0.69
1.2
1.1
—
—
—
0
0
16
110
1.46
0.68
1.5
1.5
—
—
—
0
0
16
110
1.46
0.68
1.5
1.5
—
—
—
0
0
16
110
1.46
0.68
1.5
1.5
—
—
—
0
0
16
110
1.46
0.68
1.5
1.5
—
—
—
0
0
7
42
1.67
0.68
1.0
1.2
—
—
—
0
0
7
44
1.60
0.65
2.9
1.3
—
—
—
0
0
7
44
1.60
0.65
1.0
1.2
71.86
98.20
pmol/l
—
7
44
77
665
1.17
0.64
1.2
1.4
—
—
—
0
0
13
87
1.50
0.63
1.5
1.3
266.69
275.66
mosm/kgh2o
0.71
13
61
19
138
1.39
0.63
1.3
1.2
—
—
—
0
0
15
104
1.45
0.62
2.9
2.1
10.40
10.87
mmol/l
0.22
15
104
29
226
1.29
0.62
2.9
4.9
—
—
—
0
0
42
344
1.23
0.61
1.2
1.2
—
—
—
0
0
14
198
0.70
0.60
1.1
1.1
—
—
—
0
0
21
157
1.35
0.59
4.2
4.0
34.80
32.82
mg/l
0.08
16
111
13
90
1.45
0.55
1.4
1.1
—
—
—
0
0
9
60
1.51
0.54
1.9
2.7
—
—
—
0
0
20
151
1.33
0.54
3.1
2.0
1.05
0.83
%
1.17
13
110
9
62
1.46
0.53
1.2
1.5
—
—
—
0
0
6
39
1.54
0.53
2.0
1.8
40.72
36.85
%
—
6
39
10
66
1.52
0.52
1.5
1.3
—
—
—
0
0
12
169
0.71
0.52
1.2
1.2
—
—
—
0
0
34
279
1.23
0.50
3.8
3.5
0.80
0.79
nmol/l
0.01
27
226
8
117
0.68
0.46
1.3
1.3
—
—
—
0
0
10
69
1.45
0.44
1.3
1.6
16.04
44.78
ng/l
—
10
69
188
1998
0.92
0.41
3.1
3.6
0.70
0.83
ug/l
1.28
131
1437
5
33
1.52
0.41
3.8
3.5
—
—
—
0
0
5
33
1.52
0.41
2.0
1.4
10.28
20.54
umol/l
—
5
28
0
15
0.00
0.41
0.0
2.7
—
2.37
—
0
15
5
34
1.47
0.40
1.2
2.5
20893.20
682.48
e6/l
—
5
29
8
61
1.31
0.39
1.0
1.3
—
—
—
0
0
10
71
1.41
0.39
1.1
1.1
—
19.04
—
0
14
0
19
0.00
0.39
0.0
1.9
—
—
—
0
0
15
115
1.31
0.39
1.6
1.6
—
—
—
0
0
5
36
1.39
0.38
3.8
3.5
—
—
—
0
0
34
290
1.18
0.37
1.2
1.2
91.61
139.14
u/ml
—
8
100
11
82
1.35
0.34
1.6
1.7
9.68
9.51
%
0.05
11
82
6
90
0.66
0.33
1.5
1.1
1.52
1.59
g/l
—
6
80
7
52
1.35
0.31
2.9
1.3
—
—
—
0
0
7
56
1.25
0.29
2.9
1.3
—
—
—
0
0
7
56
1.25
0.29
2.9
1.3
—
—
—
0
0
34
386
0.88
0.28
1.1
1.3
—
—
—
0
0
8
63
1.27
0.28
1.0
1.2
—
121.00
—
0
5
8
67
1.20
0.26
1.1
1.4
—
—
—
0
0
9
74
1.22
0.25
1.7
1.6
4.79
4.15
mg/l
—
9
69
14
114
1.23
0.25
1.4
1.3
8.48
8.06
u/l
—
9
85
33
371
0.89
0.25
2.3
2.0
—
—
—
0
0
19
223
0.85
0.24
1.7
1.9
2.39
3.42
mmol/l
3.52
13
165
12
96
1.25
0.24
7.5
5.2
—
—
—
0
0
10
78
1.29
0.24
1.1
1.0
—
—
—
0
0
186
1934
0.95
0.23
4.3
3.5
—
—
—
0
0
5
39
1.28
0.23
1.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
5.32
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
65
605
1.08
0.21
1.6
1.5
—
—
—
0
0
264
2565
1.04
0.21
2.0
1.9
1.35
1.27
mmol/l
1.11
223
2090
0
13
0.00
0.21
0.0
3.5
—
6153.23
—
0
13
6
49
1.23
0.20
3.3
2.3
—
—
—
0
0
39
356
1.10
0.19
2.1
2.3
0.13
0.00
estimate
—
8
95
11
90
1.23
0.19
2.7
5.0
376.09
361.50
umol/l
0.08
11
84
62
580
1.07
0.18
5.6
4.2
—
—
—
0
0
7
60
1.17
0.18
1.1
1.3
—
—
—
0
0
7
61
1.15
0.17
1.1
1.1
—
—
—
0
0
8
68
1.18
0.16
1.5
2.7
15.90
16.09
%
—
8
68
59
627
0.94
0.16
2.4
2.3
11.66
12.76
nmol/l
0.47
46
545
8
72
1.11
0.16
1.1
1.1
—
—
—
0
0
11
129
0.85
0.14
3.2
2.9
—
—
—
0
0
14
122
1.15
0.14
1.1
1.1
—
—
—
0
0
17
152
1.12
0.12
6.3
2.7
51.76
59.41
%
1.15
17
152
202
1976
1.03
0.12
4.7
3.8
0.01
0.06
estimate
0.49
76
633
11
95
1.16
0.11
1.2
1.1
—
—
—
0
0
10
115
0.87
0.10
1.2
1.8
—
—
—
0
0
11
125
0.88
0.10
1.1
1.4
—
—
—
0
0
14
126
1.11
0.09
1.4
1.6
—
—
—
0
0
14
126
1.11
0.09
1.6
1.5
—
—
—
0
0
6
55
1.09
0.09
3.2
1.3
—
—
—
0
0
27
253
1.07
0.08
1.3
1.3
—
—
—
0
0
6
57
1.05
0.08
3.2
1.3
—
—
—
0
0
6
58
1.03
0.08
1.5
1.3
—
—
—
0
0
10
88
1.14
0.08
2.1
2.4
—
—
—
0
0
7
83
0.84
0.07
1.4
1.2
1.51
1.54
g/l
—
7
83
14
128
1.10
0.06
1.1
1.2
—
—
—
0
0
56
542
1.04
0.06
1.6
1.5
—
—
—
0
0
14
136
1.03
0.00
2.0
2.4
—
—
—
0
0
6
68
0.88
0.00
1.3
1.2
1.20
1.69
nmol/l
—
6
61
0
6
0.00
-0.00
0.0
1.7
—
9.10
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.06
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
94
0.96
-0.00
1.3
1.3
0.85
0.92
g/l
—
9
94
23
230
1.00
-0.00
1.9
1.6
0.19
0.29
mg/l
0.63
11
104
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
6.66
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_CENTRRETARTOCC and mortality.

Females

Parameter HR [95% CI] p-value
H7_CENTRRETARTOCC 1.489 [1.29, 1.71] < 0.001
Birth year 0.99 [0.98, 1.0] 0.027

During the follow-up period (1.1.1998 — 31.12.2019), 869 out of 1918 females with H7_CENTRRETARTOCC died.

Males

Parameter HR [95% CI] p-value
H7_CENTRRETARTOCC 1.483 [1.29, 1.7] < 0.001
Birth year 0.989 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 1259 out of 2717 males with H7_CENTRRETARTOCC died.

Mortality risk

Mortality risk for people of age

years, who have H7_CENTRRETARTOCC.

N-year risk Females Males
1 0.101% 0.298%
5 0.648% 1.86%
10 1.66% 4.71%
15 3.185% 8.66%
20 5.884% 14.684%

Relationships between endpoints

↥

Index endpoint: H7_CENTRRETARTOCC – Central retinal artery occlusion

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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