Dissection of aorta

I9_AORTDIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

1417

4. Check minimum number of events

None

1417

5. Include endpoints

None

1417

6. Filter based on genotype QC (FinnGen only)

1262

Control definitions (FinnGen only)

Control exclude
I9_DOAAC

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10468 3661 6638
Only index persons 6613 2366 4247
Unadjusted period prevalence (%)
Whole population 0.16 0.10 0.19
Only index persons 0.14 0.09 0.16
Median age at first event (years)
Whole population 69.07 73.63 66.56
Only index persons 68.47 73.10 65.89

-FinnGen-

Key figures

All Female Male
Number of individuals 1262 351 911
Unadjusted period prevalence (%) 0.34 0.12 0.42
Median age at first event (years) 67.53 68.91 66.99

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1304
Matched controls
13040
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I71.0
ICD-10 Finland
Dissection of aorta [any part]
+∞
310.1
285
*
I71.09
ICD-10 Finland
Aortic dissection [regardless of location]
+∞
307.7
552
*
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
661.8
307.7
380
8
PD5AD
NOMESCO Finland
CT of aorta
35.2
307.7
323
121
PD5BD
NOMESCO Finland
Extensive CT of aorta
95.3
307.7
360
52
I71.01
ICD-10 Finland
Aneurysm of the descending aorta
+∞
307.7
385
*
I71.00
ICD-10 Finland
Dissecting aneurysm of aorta (ruptured) [any part]
10667.9
307.7
606
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
37.9
295.4
186
57
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
1063.0
272.0
257
*
FCA50
NOMESCO Finland
Resection and reconstruction of ascending aorta using tube graft
2424.0
230.1
216
*
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
859.2
226.3
216
*
WX872
NOMESCO Finland
Intensive care
9.6
199.7
263
336
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
14.2
189.4
182
147
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
8.2
186.1
283
428
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
8.1
163.1
244
360
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.8
158.4
520
1589
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
14.8
144.4
133
99
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
7.9
129.9
193
280
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
682.2
127.7
124
*
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
62.5
127.7
71
12
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
4.1
126.3
499
1708
ZXE30
NOMESCO Finland
More than five and less than seven hours
8.0
126.2
186
267
PD5CD
NOMESCO Finland
Very extensive CT angiography of aorta
57.7
125.8
71
13
I71.1
ICD-10 Finland
Thoracic aortic aneurysm, ruptured
+∞
117.5
111
*
FCC45
NOMESCO Finland
Percutaneous insertion of stent into descending aorta
1199.0
114.4
110
*
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
597.6
112.7
110
*
B01AA03
ATC
warfarin; systemic
3.6
109.5
559
2238
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
8.2
108.0
152
206
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
56.1
104.0
59
11
ZXE40
NOMESCO Finland
More than seven and less than nine hours
11.8
102.7
108
99
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
+∞
100.3
95
*
AJ2
HP
Reconstruction of the ascending aorta
+∞
98.2
93
*
WX892
NOMESCO Finland
Monitored bed care
4.8
92.5
238
578
ZXD05
NOMESCO Finland
Urgent procedure
3.2
88.0
555
2462
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.3
82.4
180
379
TPH07
NOMESCO Finland
Cathetrisation of artery
3.9
81.6
289
887
PD6ZT
NOMESCO Finland
Stent grafting of thoracic aorta
838.6
81.4
79
*
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
+∞
80.0
76
*
PC1BD
NOMESCO Finland
Extensive CT of thoracic aorta
123.3
75.8
81
7
C07AB07
ATC
bisoprolol; oral
3.0
73.6
898
5539
WX408
NOMESCO Finland
General anesthesy, balanced
3.0
71.8
465
2050
Q23.11
ICD-10 Finland
Bicuspid aortic valve
23.1
67.1
49
22
I71.3
ICD-10 Finland
Abdominal aortic aneurysm, ruptured
+∞
65.1
62
*
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
10.8
62.8
69
67
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.7
62.0
470
2222
FCB40
NOMESCO Finland
Resection and reconstruction of aortic arch using tube graft
+∞
59.9
57
*
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
78.5
59.7
67
9
ZXE20
NOMESCO Finland
More than three and less than five hours
3.2
59.2
284
1043
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
14.4
59.0
54
39
FCA70
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of biological valve prosthesis and tube graft
+∞
58.8
56
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.9
57.3
345
1438
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
9.2
55.7
69
79
I70.0
ICD-10 Finland
Atherosclerosis of aorta
282.3
53.6
54
*
Z31.5
ICD-10 Finland
Genetic counselling
6.3
52.9
92
155
205
Kela drug reimbursment
Chronic hypertension
2.5
52.8
560
3060
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
49.8
783
5043
C08CA01
ATC
amlodipine; oral
2.3
49.4
677
4106
FCB50
NOMESCO Finland
Resection of aortic arch and reimplantation of branches
+∞
48.2
46
*
AJ3
HP
Reconstruction of the aortic arch
+∞
47.2
45
*
FCC50
NOMESCO Finland
Resection and reconstruction of descending aorta using tube graft
+∞
47.2
45
*
Q87.4
ICD-10 Finland
Marfan syndrome
127.2
46.1
49
*
I71.6
ICD-10 Finland
Thoracoabdominal aortic aneurysm, without mention of rupture
+∞
44.0
42
*
PDG51
NOMESCO Finland
Bypass from aorta to iliac artery for aneurysm
+∞
44.0
42
*
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
441.8
43.5
43
*
PD5BG
NOMESCO Finland
MRI examination of thoracal and abdominal aortta with high intensity magnet
441.8
43.5
43
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.0
43.4
132
357
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.2
42.3
90
183
Z2221
NOMESCO Finland
Medical doctor
2.3
41.1
410
2135
K83
ICPC
Heart valve disease NOS
10.3
40.9
46
46
4410A
ICD-9 Finland
Aortic aneurysm, Dissecting aneurysm[ANEURYSMA AORTAE DISSECANS]
+∞
40.8
39
*
PD1AE
NOMESCO Finland
Ultrasound examination of abdominal aortta
77.7
40.1
45
6
TK800
NOMESCO Finland
Hemodialysis
6.9
39.7
62
93
R4110
NOMESCO Finland
Physiotherapy
2.3
38.8
430
2331
PAH12
NOMESCO Finland
Bypass from common carotid artery
+∞
37.7
36
*
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
11.8
37.1
38
33
PDG05
NOMESCO Finland
Operation on infrarenal abdominal aorta for aneurysm
+∞
36.6
35
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.2
36.5
471
2701
I71
ICD-10 Finland
Aortic aneurysm and dissection
356.5
35.1
35
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.1
33.5
419
2359
B01AB05
ATC
enoxaparin; parenteral
2.1
33.3
479
2841
ZXD00
NOMESCO Finland
Emergency procedure
4.9
33.0
75
161
I31.2
ICD-10 Finland
Haemopericardium, not elsewhere classified
45.8
32.9
40
9
PDQ05
NOMESCO Finland
Insertion of endovascular graft into infrarenal abdominal aorta
174.4
32.9
34
*
TFP20
NOMESCO Finland
Cardiodefibrillation
2.9
32.7
169
635
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.1
32.1
91
233
I10
ICD-10 Finland
Essential (primary) hypertension
2.1
31.7
936
7127
Z3231
NOMESCO Finland
Registered nurse
2.1
31.6
403
2276
I70.1
ICD-10 Finland
Atherosclerosis of renal artery
+∞
31.4
30
*
PD5CM
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
31.4
30
*
TKC20
NOMESCO Finland
Catheterisation of bladder
2.9
30.6
161
610
C02AC05
ATC
moxonidine; oral
3.5
30.2
109
330
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
309.3
29.9
30
*
FC1AC
NOMESCO Finland
Angiography of thoracal aortta
10.6
29.9
33
32
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
29.8
441
2623
PD5DG
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
+∞
29.3
28
*
PD7ZT
NOMESCO Finland
Stent grafting of abdominal aorta
+∞
29.3
28
*
I72.3
ICD-10 Finland
Aneurysm and dissection of iliac artery
+∞
29.3
28
*
C08CA02
ATC
felodipine; oral
2.5
28.2
192
828
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.9
27.8
62
131
PA1BD
NOMESCO Finland
Extensive CT of aortic arch and branches
148.2
27.7
29
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.6
27.7
175
728
Z3226
NOMESCO Finland
Physiotherapist
2.2
27.5
277
1418
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
27.3
129
460
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
27.2
217
1006
C07AB02
ATC
metoprolol; systemic
2.0
26.7
361
2065
K84
ICPC
Heart disease other
4.0
26.2
76
198
PD5YT
NOMESCO Finland
Implantation of aorttaprothesis for aortta aneurysm
+∞
26.1
25
*
C03DA01
ATC
spironolactone; oral
2.3
25.6
230
1120
PC1BC
NOMESCO Finland
Extensive angiography of aorta and abdominal arteries
45.3
25.6
31
7
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.4
25.3
95
295
AJ5
HP
Reconstruction of the descending thoracic aorta with a stent graft
+∞
25.1
24
*
C03CA01
ATC
furosemide; systemic
1.8
24.8
553
3716
26
HP
Aortic root """"composite graft""""
254.8
24.8
25
*
XPX00
NOMESCO Finland
Intraoperative angiography
254.8
24.8
25
*
I72.4
ICD-10 Finland
Aneurysm and dissection of artery of lower extremity
+∞
24.0
23
*
ZXE00
NOMESCO Finland
One hour or less
1.8
23.3
504
3340
FC1BC
NOMESCO Finland
Extensive angiography of thoracal aortta
28.8
23.2
31
11
XF404
NOMESCO Finland
Ambulatory ECG
2.5
22.6
153
655
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.5
22.5
78
230
I72.8
ICD-10 Finland
Aneurysm and dissection of other specified arteries
223.6
21.7
22
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
21.5
327
1927
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
5.0
21.2
46
95
421
HP
Reconstruction of the aortic base, e.g., composite graft
+∞
20.9
20
*
FNC10
NOMESCO Finland
Aorto-coronary venous bypass with single distal anastomosis
5.1
20.8
44
89
PG1PT
NOMESCO Finland
Extensive endovascular embolisation for bleeding with radiological guidance not elsewhere classified
30.6
20.6
27
9
AJ4
HP
Reconstruction of the descending thoracic aorta
+∞
19.8
19
*
C09AA05
ATC
ramipril; oral
1.8
19.7
416
2707
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
19.1
469
3181
K78
ICPC
Atrial fibrillation/flutter
2.3
19.0
164
780
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
19.0
494
3402
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
5.3
18.7
38
74
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.9
18.5
55
146
K99
ICPC
Cardiovascular disease other
3.5
18.4
64
189
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
7.9
18.3
25
32
R04.0
ICD-10 Finland
Epistaxis
2.4
18.1
139
629
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.4
18.1
127
552
C08CA05
ATC
nifedipine; systemic
2.5
18.0
115
478
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
18.4
17.8
27
15
FCD60
NOMESCO Finland
Resection of thoracoabdominal aorta and reimplantation of branches
+∞
17.7
17
*
TQW11
NOMESCO Finland
Vacuum treatment of wound
5.0
17.6
38
78
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.7
17.5
95
364
WX402
NOMESCO Finland
General anaesthesia
1.9
17.5
267
1565
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
17.3
132
595
N02AX02
ATC
tramadol; systemic, rectal
1.7
17.1
567
4135
I97.0
ICD-10 Finland
Postcardiotomy syndrome
19.6
16.9
25
13
XF600
NOMESCO Finland
Bloodpressure measurement
2.6
16.9
98
389
C01BD01
ATC
amiodarone; systemic
3.4
16.7
62
191
I71.8
ICD-10 Finland
Aortic aneurysm of unspecified site, ruptured
+∞
16.7
16
*
PD3YT
NOMESCO Finland
Pelvic artery PTA with stent
+∞
16.7
16
*
PC1AC
NOMESCO Finland
Angiography of aorta and abdominal arteries
91.3
16.6
18
*
AA1AD
NOMESCO Finland
CT of head and brain
1.7
16.6
443
3049
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
16.5
236
1351
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.7
16.5
403
2707
AN1
HP
Coronary angiography
2.0
16.5
198
1068
XF640, ,
NOMESCO Finland
3.5
16.4
57
168
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.2
16.4
44
108
C03AA03
ATC
hydrochlorothiazide; oral
2.2
16.1
152
748
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.4
16.0
58
176
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
15.9
144
698
A12BA01
ATC
potassium chloride; oral
2.6
15.8
91
359
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
15.8
318
2021
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.1
15.8
66
219
I77.6
ICD-10 Finland
Arteritis, unspecified
+∞
15.7
15
*
4410B
ICD-9 Finland
Aortic aneurysm, Dissecting aneurysm[DISSECATIO AORTAE SINE ANEURYSMATE]
+∞
15.7
15
*
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
86.1
15.6
17
*
WX890
NOMESCO Finland
Intesive care monitoring
7.1
15.3
23
33
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
15.1
187
1019
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
15.0
177
947
ZX120
NOMESCO Finland
Intravenous
2.2
14.6
134
652
PE1AT
NOMESCO Finland
Femoral artery PTA
+∞
14.6
14
*
PD5DM
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
14.6
14
*
FXA13
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and exclusive cerebral perfusion
+∞
14.6
14
*
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
151.6
14.5
15
*
PD1CD
NOMESCO Finland
Very extensive CT of abdominal aorta and branches
36.5
14.5
18
5
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.6
14.4
84
334
M01AH05
ATC
etoricoxib; oral
0.6
14.2
405
5509
Z50.0
ICD-10 Finland
Cardiac rehabilitation
5.2
14.1
29
57
I74.3
ICD-10 Finland
Embolism and thrombosis of arteries of lower extremities
43.0
14.1
17
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.5
14.1
93
393
WW502
NOMESCO Finland
Autotransfusion
11.0
14.0
26
24
207
Kela drug reimbursment
Chronic arrhythmias
1.7
14.0
281
1778
GD1AD
NOMESCO Finland
Thorax CT examination
2.3
13.9
106
477
3A064, ,
NOMESCO Finland
17.8
13.8
21
12
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
6.6
13.7
22
34
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.1
13.6
147
761
XA800
NOMESCO Finland
Neuropsychological investigation
3.0
13.5
59
201
3A149, ,
NOMESCO Finland
141.4
13.5
14
*
T82.7
ICD-10 Finland
Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
21.4
13.3
19
9
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
13.3
111
519
WX870
NOMESCO Finland
Other postsurgical intensive care
10.6
13.3
25
24
J01XX08
ATC
linezolid; systemic
10.6
13.3
25
24
C09AA02
ATC
enalapril; systemic
1.7
13.2
303
1983
WX882
NOMESCO Finland
High dependency care
3.3
13.2
50
156
3A422, ,
NOMESCO Finland
40.5
13.2
16
*
C10AA01
ATC
simvastatin; oral
1.5
13.1
612
4748
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
22.8
12.9
18
8
Z2446
NOMESCO Finland
Social worker
2.5
12.9
86
365
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.0
12.7
138
715
R06.0
ICD-10 Finland
Dyspnoea
1.6
12.7
371
2581
474, ,
NOMESCO Finland
70.6
12.6
14
*
PWE00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of peripheral vessels and lymphatic system
32.4
12.6
16
5
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
32.4
12.6
16
5
I72.2
ICD-10 Finland
Aneurysm and dissection of renal artery
+∞
12.5
12
*
PDH51
NOMESCO Finland
Bypass from aorta to bilateral iliac arteries
+∞
12.5
12
*
4414A
ICD-9 Finland
Aortic aneurysm, Abdominal aneurysm without mention of rupture
+∞
12.5
12
*
PD6YT
NOMESCO Finland
Stenting of stenosis in thoracic aorta
+∞
12.5
12
*
42
HP
Thoracic aortic surgery
+∞
12.5
12
*
FCA75
NOMESCO Finland
Valve-sparing repair of aortic root (David, Yacoub)
+∞
12.5
12
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.2
12.5
112
540
PEN23
NOMESCO Finland
Plastic repair of femoral artery
131.2
12.5
13
*
120, ,
NOMESCO Finland
131.2
12.5
13
*
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
13.3
12.4
21
16
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
2.6
12.4
73
292
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
2.0
12.3
137
716
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
12.2
217
1322
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.8
12.2
63
236
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
2.9
12.1
57
203
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.5
12.0
78
327
XFE00
NOMESCO Finland
Epicardial ultrasonography
3.3
11.8
44
136
PD1AD
NOMESCO Finland
CT of abdominal aorta and branches
10.6
11.8
22
21
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.4
11.7
80
343
4412A
ICD-9 Finland
Aortic aneurysm, Thoracic aneurysm without mention of rupture
+∞
11.5
11
*
PDG54
NOMESCO Finland
Bypass from aorta to femoral artery for aneurysm
+∞
11.5
11
*
I72.1
ICD-10 Finland
Aneurysm and dissection of artery of upper extremity
121.0
11.4
12
*
B01AB04
ATC
dalteparin; parenteral
2.5
11.4
71
292
J01MA12
ATC
levofloxacin; systemic
1.7
11.3
263
1721
R4120
NOMESCO Finland
Occupational therapy
2.3
11.1
85
384
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
5.3
11.1
22
42
ZXE90
NOMESCO Finland
More than 22 hours
8.7
11.0
23
27
C02CA01
ATC
prazosin; oral
3.4
11.0
40
122
NFQ20
NOMESCO Finland
Amputation of femur
43.7
10.9
13
*
PA6AD
NOMESCO Finland
CT of neck arteries
2.6
10.8
61
239
PD4DG
NOMESCO Finland
Very extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
110.9
10.4
11
*
PEA23
NOMESCO Finland
Exploration of femoral artery
110.9
10.4
11
*
PDQ20
NOMESCO Finland
Insertion of endovascular graft into common iliac artery
+∞
10.4
10
*
NHQ40
NOMESCO Finland
Amputation of toe
+∞
10.4
10
*
PCQ99
NOMESCO Finland
Insertion of endovascular graft into other visceral artery
+∞
10.4
10
*
PGH47
NOMESCO Finland
Bypass from femoral to contralateral femoral artery
+∞
10.4
10
*
PD1YT
NOMESCO Finland
Implantaion of endoprothesis to aortta in conjunction to PTA
+∞
10.4
10
*
K29
ICPC
Cardiovascular sympt/complt other
2.4
10.3
71
306
PC1CC
NOMESCO Finland
Very extensive angiography of aorta and abdominal arteries
23.6
10.2
14
6
A02BC02
ATC
pantoprazole; systemic
1.5
10.2
827
7032
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
10.2
38
118
C01AA05
ATC
digoxin; systemic
1.8
10.0
157
918
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
4.0
9.9
28
72
DQE10
NOMESCO Finland
Injection of foreign material into vocal cord
12.3
9.9
17
14
N18.8
ICD-10 Finland
Other chronic renal failure
3.0
9.8
43
147
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
2.5
9.8
63
263
C07AG02
ATC
carvedilol; oral
2.1
9.7
94
468
I50.0
ICD-10 Finland
Congestive heart failure
1.9
9.7
132
740
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
9.7
256
1725
XF402
NOMESCO Finland
ECG with work load test
1.8
9.4
148
866
I70.8
ICD-10 Finland
Atherosclerosis of other arteries
100.7
9.4
10
*
PE1YT
NOMESCO Finland
Femoral or popliteal artery PTA with stent
100.7
9.4
10
*
PD3AT
NOMESCO Finland
Pelvic artery PTA
100.7
9.4
10
*
81
HP
Angiography of the heart and coronary arteries
2.0
9.4
111
593
PCQ17
NOMESCO Finland
Insertion of endovascular graft into superior mesenteric artery
+∞
9.4
9
*
PDH99
NOMESCO Finland
Other bypass from abdominal aorta or iliac artery
+∞
9.4
9
*
422
HP
Ascending aortic reconstruction
+∞
9.4
9
*
PCQ16
NOMESCO Finland
Insertion of endovascular graft into coeliac trunk and branches
+∞
9.4
9
*
FCA96
NOMESCO Finland
Other repair of ascending aorta
+∞
9.4
9
*
5518
FHL
Ascending aortic aneurysm surgery, aortic valve prosthesis and coronary implantation
+∞
9.4
9
*
I74.1
ICD-10 Finland
Embolism and thrombosis of other and unspecified parts of aorta
+∞
9.4
9
*
GBB00
NOMESCO Finland
Tracheostomy
3.9
9.3
27
71
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.5
9.2
31
90
I73.9
ICD-10 Finland
Peripheral vascular disease, unspecified
13.8
9.2
15
11
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
9.1
818
9252
J01MA02
ATC
ciprofloxacin; systemic
1.4
9.1
504
3956
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
3.5
9.1
30
86
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
4.8
9.1
20
42
742, ,
NOMESCO Finland
15.7
9.0
14
9
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
7.1
9.0
21
30
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.7
9.0
171
1057
R4130
NOMESCO Finland
Speech therapy
2.9
8.9
42
150
J04AB02
ATC
rifampicin; systemic
4.0
8.9
25
64
R50.9
ICD-10 Finland
Fever, unspecified
1.7
8.9
192
1229
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
8.8
163
999
PC5YT
NOMESCO Finland
Stenting of renal artery
50.3
8.7
10
*
PD4CC
NOMESCO Finland
Very extensive arterigography of lower extremity with X-ray
50.3
8.7
10
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
4.3
8.7
22
52
G45.3
ICD-10 Finland
Amaurosis fugax
3.1
8.6
36
120
C01DA14
ATC
isosorbide mononitrate; oral
1.5
8.6
264
1836
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.8
8.6
19
40
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
3.0
8.6
38
131
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.1
8.6
76
365
PC5SC
NOMESCO Finland
Selective angiography of kidney artery with X-ray
90.6
8.4
9
*
RS221, ,
NOMESCO Finland
4.5
8.4
20
45
TK810
NOMESCO Finland
Hemofiltration
7.9
8.4
18
23
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
4.0
8.4
23
58
PFG26
NOMESCO Finland
Operation for aneurysm of popliteal artery
+∞
8.3
8
*
4402A
ICD-9 Finland
Atherosclerosis, Of native arteries of the extremities
+∞
8.3
8
*
K55.0
ICD-10 Finland
Acute vascular disorders of intestine
+∞
8.3
8
*
I74.4
ICD-10 Finland
Embolism and thrombosis of arteries of extremities, unspecified
+∞
8.3
8
*
424
HP
Reconstruction of the descending thoracic aorta
+∞
8.3
8
*
PCQ04
NOMESCO Finland
Insertion of endovascular graft into suprarenal abdominal aorta
+∞
8.3
8
*
AP1
HP
Catheterization of the left side of the heart
3.2
8.3
32
102
R31
ICD-10 Finland
Unspecified haematuria
1.6
8.2
180
1154
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
4.3
8.2
21
50
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
3.1
8.2
34
113
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
4.6
8.1
19
42
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.8
8.1
123
713
51
HP
Other heart surgery
33.6
8.1
10
*
PEC23
NOMESCO Finland
Suture of common femoral artery
11.8
8.1
14
12
AB1
HP
AVR mechanical
9.0
8.0
16
18
XPX08
NOMESCO Finland
Intraoperative flow measurement
10.1
8.0
15
15
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
2.4
8.0
53
225
C09CA01
ATC
losartan; oral
1.5
7.9
335
2489
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.3
7.9
59
265
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.0
7.8
34
116
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
4.1
7.8
21
52
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
2.9
7.8
35
122
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.3
7.8
55
241
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.1
7.7
72
353
FWW96
NOMESCO Finland
Other reoperation on heart or major thoracic vessels
15.1
7.7
12
8
ZPB32
NOMESCO Finland
Covered dacron
45.2
7.7
9
*
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
7.6
238
1659
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
7.6
373
2845
M01AC06
ATC
meloxicam; systemic, rectal
0.7
7.6
221
3105
4241A
ICD-9 Finland
Other diseases of endocardium, Aortic valve disorders[INSUFFICIENTIA VALVULAE AORTAE (NON RHEUMATICA)]
25.2
7.6
10
*
AJX
HP
Other surgery on the heart or aorta
25.2
7.6
10
*
R03BB04
ATC
tiotropium bromide; inhalant
1.7
7.5
149
930
J01FF01
ATC
clindamycin; systemic
1.5
7.5
289
2103
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
7.4
260
1855
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.1
7.4
71
352
R07.3
ICD-10 Finland
Other chest pain
1.7
7.4
127
763
I35.8
ICD-10 Finland
Other aortic valve disorders
7.7
7.4
16
21
NGM10
NOMESCO Finland
Fasciotomy of of knee or lower leg
8.4
7.3
15
18
5253
FHL
Cardiac lung machine
3.6
7.3
23
64
7598B
ICD-9 Finland
Other and unspecified congenital anomalies, Other specified anomalies[SYNDROMA MARFAN]
+∞
7.3
7
*
FC1CC
NOMESCO Finland
Very extensive angiography of thoracal aortta
+∞
7.3
7
*
PG1LT
NOMESCO Finland
Extensive occlusion of aneurysm with radiological guidance not elsewhere classified
+∞
7.3
7
*
FXB00
NOMESCO Finland
Intraoperative partial cardiopulmonary bypass
+∞
7.3
7
*
5526
FHL
Surgery of an unrupturated abdominal aneurysm
+∞
7.3
7
*
PEH57
NOMESCO Finland
Bypass from femoral artery to popliteal artery below knee
+∞
7.3
7
*
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
9.4
7.3
14
15
WX704
NOMESCO Finland
Intubation
1.9
7.3
94
518
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.6
7.2
40
156
ZXA00
NOMESCO Finland
Right side
1.4
7.2
321
2401
C10AA05
ATC
atorvastatin; oral
1.4
7.2
542
4441
S97
ICPC
Chronic ulcer skin
1.9
7.2
83
441
PG9AC
NOMESCO Finland
Arteriography with X-ray not elsewhere classified
30.2
7.2
9
*
I50
ICD-10 Finland
Heart failure
2.3
7.1
54
245
Z82.4
ICD-10 Finland
Family history of ischaemic heart disease and other diseases of the circulatory system
10.1
7.0
13
13
A11CC03
ATC
alfacalcidol; systemic
2.7
6.9
35
131
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.3
6.9
49
216
X57
ICD-10 Finland
Unspecified privation
2.9
6.8
31
109
AB2
HP
AVR bio, stent
6.1
6.8
17
28
G95.1
ICD-10 Finland
Vascular myelopathies
40.3
6.8
8
*
PWC00
NOMESCO Finland
Reoperation for deep infection in surgery of peripheral vessels and lymphatic system
40.3
6.8
8
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
6.6
131
818
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.6
6.5
164
1086
Y88.1
ICD-10 Finland
Sequelae of misadventures to patients during surgical and medical procedures
3.4
6.4
22
65
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
70.2
6.4
7
*
I38
ICD-10 Finland
Endocarditis, valve unspecified
14.4
6.4
10
7
J98.5
ICD-10 Finland
Diseases of mediastinum, not elsewhere classified
14.4
6.4
10
7
PG1NT
NOMESCO Finland
Endovascular embolisation for bleeding with radiological guidance not elsewhere classified
14.4
6.4
10
7
B01AF02
ATC
apixaban; oral
1.5
6.4
197
1367
WX002
NOMESCO Finland
Sedation and analgesia
1.5
6.4
228
1632
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
8.2
6.3
13
16
21
HP
Aortic Valve Replacement (AVR)
11.1
6.3
11
10
PEH56
NOMESCO Finland
Bypass from femoral to popliteal artery above knee
+∞
6.3
6
*
PFE26
NOMESCO Finland
Thrombectomy or embolectomy of popliteal artery
+∞
6.3
6
*
I71.5
ICD-10 Finland
Thoracoabdominal aortic aneurysm, ruptured
+∞
6.3
6
*
PCG04
NOMESCO Finland
Operation for aneurysm of supracoeliac or juxtarenal abdominal aorta
+∞
6.3
6
*
PD1BT
NOMESCO Finland
Extensive PTA of aortta
+∞
6.3
6
*
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
+∞
6.3
6
*
PEF24
NOMESCO Finland
Thrombendarterectomy of deep femoral artery
+∞
6.3
6
*
FCD35
NOMESCO Finland
Percutaneous insertion of stent into thoracoabdominal aorta
+∞
6.3
6
*
PE1BT
NOMESCO Finland
Femoral artery extensive PTA
+∞
6.3
6
*
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
6.2
79
433
PA1AD
NOMESCO Finland
CT of aortic arch and branches
26.8
6.2
8
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
1.8
6.2
85
478
DKW30
NOMESCO Finland
Cauterisation of artery of internal nose
5.4
6.2
17
32
I20.09
ICD-10 Finland
Unstable angina
1.8
6.1
85
480
N03AX16
ATC
[U] pregabalin
1.5
6.1
244
1785
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.0
6.0
59
296

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
324
1117
3.53
76.48
8.3
5.9
10.00
10.95
mmol/l
1.62
305
1057
415
1816
2.89
63.82
3.4
1.8
31.36
29.64
s
3.51
406
1764
141
330
4.67
56.34
3.1
1.7
21.90
21.09
s
0.72
135
304
865
5682
2.55
54.85
49.7
17.7
1.70
1.35
inr
34.06
774
4783
281
1097
2.99
52.11
2.6
2.4
17.85
7.01
ug/l
3.24
264
973
91
154
6.28
52.07
6.3
5.8
11.34
12.12
mg/l
0.79
83
143
319
1485
2.52
41.00
19.4
6.7
7.42
7.42
ph
0.16
175
830
256
1070
2.73
41.00
19.4
7.7
—
—
—
0
0
294
1329
2.57
40.11
20.2
7.0
95.70
95.46
%
0.23
284
1287
316
1484
2.49
39.72
19.4
6.7
1.23
0.98
mmol/l
0.59
276
1213
315
1498
2.45
38.38
19.4
6.7
12.05
11.90
kpa
0.18
307
1434
315
1498
2.45
38.38
19.5
6.7
5.16
5.09
kpa
0.67
307
1434
581
3595
2.11
37.02
6.2
4.2
—
—
—
0
0
205
814
2.80
35.94
24.7
8.4
1.40
1.27
%
1.49
205
809
199
785
2.81
35.29
25.5
8.7
0.65
0.65
%
0.06
199
780
315
1554
2.35
34.99
6.9
5.4
1.04
1.02
mmol/l
0.52
299
1447
369
1956
2.24
34.50
3.8
3.0
0.84
0.81
mmol/l
4.40
352
1840
421
2360
2.16
34.15
5.7
4.1
1323.57
369.36
ng/l
1.22
386
2010
607
3959
2.00
32.11
4.4
3.1
2176.01
1543.83
ng/l
1.59
558
3438
452
2742
1.99
28.63
6.7
4.1
72.08
83.57
%
13.02
444
2695
544
3525
1.93
28.31
3.7
2.5
—
—
—
0
0
257
1275
2.26
27.53
4.9
3.4
7.37
7.38
ph
0.75
158
748
296
1564
2.15
27.08
2.5
1.9
—
—
—
0
0
182
783
2.54
26.81
21.8
7.3
24.93
24.78
mmol/l
0.22
182
778
439
2689
1.95
26.66
3.5
2.4
—
—
—
0
0
368
2148
1.99
25.52
2.8
1.6
3.31
1.53
mg/l
3.87
319
1681
35
18
19.94
23.53
4.9
7.9
5.55
5.01
kpa
0.97
35
18
138
562
2.63
22.63
2.3
1.8
1.05
2.55
ug/l
1.06
123
486
211
1055
2.19
21.81
3.9
3.1
253.18
217.88
ng/l
0.62
201
964
239
1277
2.07
20.73
4.7
3.4
5.86
5.80
kpa
0.48
233
1239
524
3617
1.75
20.36
2.7
2.2
412.57
217.05
u/l
2.47
504
3414
303
1783
1.91
19.85
3.3
2.5
19.71
22.68
%
3.53
284
1660
230
1236
2.05
19.55
4.7
3.4
1.67
1.87
mmol/l
0.31
202
1046
314
1932
1.82
17.62
3.3
2.5
2.20
2.24
g/l
0.69
290
1773
328
2061
1.79
17.10
3.3
2.5
11.11
12.59
umol/l
3.56
306
1913
136
635
2.27
16.44
1.5
1.8
1.48
1.47
g/l
0.05
109
554
828
6682
1.66
16.42
11.8
5.0
6.63
6.84
mmol/l
3.62
809
6415
644
4895
1.62
16.16
4.0
2.8
—
—
estimate
—
0
0
195
1068
1.97
15.50
3.9
2.8
4.84
4.43
kpa
0.57
189
1036
447
3130
1.65
15.42
2.8
2.3
3.26
2.86
mg/l
2.19
380
2677
739
5849
1.61
15.39
7.3
6.7
13.32
12.82
umol/l
0.62
720
5573
260
1592
1.79
14.53
2.6
2.5
1.73
1.78
%
0.31
233
1417
673
5253
1.58
14.52
15.0
6.3
1.18
1.21
mmol/l
13.70
629
4825
499
3658
1.59
13.94
7.2
5.9
—
—
—
0
0
184
1026
1.92
13.80
2.7
2.5
54.82
84.51
u/l
0.24
158
842
459
3315
1.59
13.57
3.9
3.4
0.76
0.51
e6/l
0.45
357
2486
87
365
2.48
13.36
1.2
1.2
—
—
—
0
0
292
1910
1.68
12.73
3.6
3.2
3.15
1.55
e6/l
1.31
151
974
517
3883
1.55
12.66
4.1
3.5
155.25
101.66
e6/l
0.23
406
3022
148
791
1.98
12.53
17.4
6.2
25.02
24.53
mmol/l
0.90
143
756
724
5873
1.52
12.26
14.9
7.0
1.19
1.21
mmol/l
10.68
639
5019
627
4950
1.51
11.97
7.8
6.1
61.29
58.36
%
7.62
608
4707
648
5155
1.51
11.90
6.0
5.0
33.29
35.01
g/l
10.46
601
4795
200
1200
1.79
11.81
2.3
1.6
—
—
—
0
0
548
4218
1.52
11.73
5.0
4.0
166.04
143.41
e6/l
0.21
415
3109
625
4966
1.50
11.35
8.0
6.1
2.86
2.88
%
0.06
598
4633
727
5959
1.50
11.31
10.0
9.4
4.60
4.23
e9/l
3.72
616
5132
624
4965
1.49
11.20
7.9
6.2
0.62
0.66
%
1.01
600
4627
204
1250
1.75
11.17
2.8
2.8
7.83
9.93
umol/l
0.99
188
1126
65
259
2.59
11.13
2.1
3.0
33.45
33.65
umol/l
0.03
60
229
623
4966
1.49
11.02
7.9
6.2
9.35
9.26
%
0.32
597
4638
669
5424
1.48
10.78
7.6
6.0
1.63
1.87
e9/l
3.30
582
4716
659
5349
1.47
10.42
7.6
5.9
0.04
0.04
e9/l
0.32
564
4515
656
5329
1.46
10.28
7.7
5.9
0.64
0.62
e9/l
1.69
559
4497
627
5053
1.46
10.21
7.9
6.2
22.96
25.98
%
9.24
606
4766
298
2063
1.58
10.07
3.4
3.1
2.19
1.07
e6/l
0.92
157
1132
446
3382
1.48
9.81
4.2
3.2
33.43
34.56
u/l
0.26
419
3189
576
4596
1.45
9.72
5.1
4.0
62.71
65.67
ng/l
0.07
492
3607
328
2342
1.54
9.60
3.4
3.0
552.44
550.38
mosm/kgh2o
0.06
296
2060
373
2739
1.51
9.56
3.1
2.7
3.53
4.54
e6/l
1.46
341
2506
668
5500
1.44
9.43
7.9
6.1
0.20
0.20
e9/l
0.25
574
4731
39
136
2.93
8.64
1.5
1.3
—
—
—
0
0
42
153
2.80
8.60
1.5
1.3
23601.76
41133.34
e6/l
0.48
21
92
45
171
2.69
8.52
1.5
1.3
4645.27
1703.93
e6/l
0.68
26
123
411
3137
1.45
8.49
8.5
6.3
—
—
—
0
0
562
4571
1.40
8.04
15.6
11.7
0.00
0.00
e9/l
1.00
450
3708
67
315
2.19
8.00
5.1
3.4
2.58
1.67
index
0.52
43
177
173
1108
1.65
7.94
2.2
2.4
0.21
0.20
g/l
0.44
164
1023
214
1450
1.57
7.78
1.4
1.4
—
—
—
0
0
812
7092
1.38
7.24
5.5
4.8
176.36
1973.11
e6/l
1.40
14
122
39
153
2.60
6.98
1.6
1.4
—
—
—
0
0
38
150
2.58
6.73
1.6
1.7
0.71
0.89
g/l
0.56
27
117
29
99
2.97
6.72
1.3
1.2
2.76
3.82
u/ml
0.54
17
45
551
4561
1.36
6.70
3.7
2.9
196.03
162.42
ug/l
1.31
505
4180
186
1269
1.54
6.52
1.6
1.4
—
—
—
0
0
425
3395
1.37
6.41
3.3
3.4
—
—
—
0
0
132
835
1.65
6.35
4.9
3.9
125.88
97.10
ng/l
1.34
115
711
436
3509
1.36
6.24
5.3
4.1
7.40
7.40
ph
0.22
317
2545
181
1250
1.52
5.99
2.5
2.6
67.57
67.50
e9/l
0.01
120
964
31
119
2.64
5.83
2.3
1.7
10.57
10.64
%
0.03
31
119
28
104
2.73
5.62
5.0
3.0
11.10
12.64
index
0.51
21
55
61
319
1.96
5.57
2.9
3.4
0.70
0.81
nmol/l
1.43
48
256
35
148
2.40
5.42
1.5
1.5
—
—
—
0
0
169
1177
1.50
5.36
1.7
1.6
—
—
—
0
0
24
85
2.86
5.26
2.1
2.3
6.94
7.82
mmol/l
0.87
24
85
158
1092
1.51
5.20
2.5
3.0
65.27
66.35
g/l
1.06
138
1005
40
190
2.14
4.77
1.9
2.7
—
—
—
0
0
892
8167
1.29
4.37
10.6
8.3
82.12
80.56
u/l
0.41
851
7726
32
144
2.25
4.36
1.3
1.5
—
—
—
0
0
32
144
2.25
4.36
1.3
1.5
—
—
—
0
0
32
144
2.25
4.36
1.3
1.5
—
—
—
0
0
32
144
2.25
4.36
1.3
1.5
—
—
—
0
0
78
479
1.67
4.27
2.3
2.7
9.61
10.81
g/l
1.99
71
432
269
3335
0.76
4.00
3.4
3.4
—
—
—
0
0
63
374
1.72
3.92
12.0
5.2
1.39
1.36
mmol/l
0.05
57
328
23
95
2.45
3.81
1.8
1.3
6.66
6.62
g/l
0.02
17
68
23
95
2.45
3.81
1.8
1.3
2.62
2.80
g/l
0.15
15
69
23
95
2.45
3.81
1.8
1.3
0.43
0.42
g/l
0.05
17
69
23
97
2.40
3.66
1.8
1.3
—
—
—
0
0
128
915
1.44
3.59
2.5
2.7
—
—
—
0
0
29
137
2.14
3.57
1.7
2.1
0.84
1.59
g/24h
0.94
18
83
30
146
2.08
3.43
1.7
1.8
4.10
4.53
mmol/24h
0.34
25
126
35
181
1.96
3.41
1.9
2.4
—
—
—
0
0
403
3440
1.25
3.31
3.0
2.6
60.27
86.28
u/l
0.57
379
3179
45
256
1.78
3.29
1.3
1.2
—
—
—
0
0
124
918
1.39
2.89
1.6
1.6
—
—
—
0
0
10
28
3.59
2.78
1.9
1.9
—
—
—
0
0
159
1232
1.33
2.78
1.5
1.3
414.29
389.29
titre
0.09
28
269
54
342
1.60
2.72
1.8
1.7
8.24
6.27
iu/ml
0.22
16
76
134
1016
1.36
2.71
1.6
1.5
—
—
—
0
0
21
99
2.14
2.65
1.3
1.3
—
—
—
0
0
33
185
1.80
2.58
1.3
1.2
—
—
—
0
0
31
538
0.57
2.58
1.3
1.4
—
—
—
0
0
64
431
1.51
2.49
3.0
3.3
2668.64
299.99
mg/l
0.52
33
196
10
254
0.39
2.45
1.1
1.7
—
—
—
0
0
113
854
1.35
2.36
5.0
3.6
7.42
7.42
ph
0.09
100
716
522
5756
0.84
2.32
5.4
5.9
2.62
3.90
ug/l
0.76
453
5154
20
98
2.06
2.32
1.1
1.2
—
—
—
0
0
342
2965
1.21
2.32
3.3
2.9
397.99
362.88
umol/l
5.74
292
2561
17
78
2.20
2.31
1.3
1.2
—
—
—
0
0
10
34
2.96
2.28
1.0
1.6
0.00
0.00
estimate
—
10
34
8
23
3.49
2.27
1.0
1.1
—
—
—
0
0
31
179
1.75
2.24
1.4
1.4
—
—
—
0
0
28
157
1.80
2.22
1.3
1.1
—
—
—
0
0
437
3889
1.19
2.21
3.1
3.4
2.33
2.35
mmol/l
1.44
391
3490
9
30
3.01
2.15
1.1
1.1
—
—
—
0
0
44
283
1.57
2.13
2.0
2.1
125.30
129.95
g/l
0.42
30
220
315
2732
1.20
2.11
1.4
1.3
—
—
—
0
0
82
600
1.39
2.11
2.2
2.8
—
—
—
0
0
11
43
2.57
2.08
3.1
2.2
2536.18
1202.70
u/ml
0.31
11
43
10
37
2.72
2.07
1.2
1.1
138.23
259.88
iu/ml
—
10
37
83
611
1.38
2.06
1.5
1.5
—
—
—
0
0
41
262
1.58
2.05
3.2
4.6
1.46
2.52
mmol/l
2.77
30
176
18
90
2.01
2.01
1.2
1.2
—
—
—
0
0
27
157
1.73
1.93
1.3
1.4
181.86
161.61
au/ml
—
7
40
46
307
1.52
1.92
1.4
1.6
—
—
—
0
0
54
375
1.46
1.87
1.3
1.6
—
—
—
0
0
913
9551
0.85
1.87
6.5
7.0
38.89
40.08
mmol/mol
5.44
849
8823
40
261
1.55
1.86
1.9
2.1
14.13
11.90
mg/l
0.89
35
239
43
286
1.52
1.84
2.7
3.6
—
—
—
0
0
370
4128
0.86
1.79
1.9
1.9
1.43
1.32
mmol/l
2.03
311
3401
8
29
2.77
1.79
8.3
4.4
—
—
—
0
0
61
439
1.41
1.76
3.2
3.6
9.26
3.41
ratio
0.37
38
273
66
482
1.39
1.76
3.1
3.7
123.33
62.69
mg/l
0.50
56
419
6
18
3.34
1.74
1.2
1.2
—
—
—
0
0
103
808
1.30
1.72
3.0
2.9
10.38
11.07
g/l
1.11
91
739
15
75
2.01
1.70
2.9
2.2
—
—
—
0
0
13
253
0.51
1.67
2.2
1.7
—
—
—
0
0
65
480
1.37
1.64
3.1
3.8
43.00
98.42
mg/l
0.98
55
420
39
262
1.50
1.62
1.1
1.1
—
—
—
0
0
32
483
0.65
1.60
1.6
1.8
3.13
3.48
mmol/l
0.96
23
362
80
615
1.32
1.56
5.9
3.7
—
—
—
0
0
263
2305
1.18
1.56
1.8
1.8
1045.36
1157.64
nmol/l
1.23
200
1757
0
44
0.00
1.51
0.0
1.2
—
39.00
—
0
20
64
479
1.35
1.50
4.2
3.3
4.09
4.46
pmol/l
2.74
57
416
480
4419
1.14
1.44
3.9
3.5
6.26
6.22
ph
0.28
237
2461
114
930
1.25
1.42
1.7
1.5
—
—
—
0
0
26
167
1.57
1.35
1.1
1.2
328.57
265.53
u/ml
0.32
21
89
21
129
1.64
1.30
1.0
1.3
279.88
274.83
mosm/kgh2o
0.35
16
98
1037
10663
0.87
1.30
46.3
27.4
127.17
134.90
g/l
36.34
1025
10503
14
76
1.85
1.30
2.7
3.0
—
—
—
0
0
1037
10662
0.87
1.29
45.9
27.1
4.25
4.46
e12/l
24.36
1010
10373
1037
10662
0.87
1.29
49.7
27.6
38.33
40.13
%
20.04
1024
10494
1037
10662
0.87
1.29
45.8
27.0
30.32
30.54
pg
3.75
1024
10500
1037
10660
0.87
1.28
45.9
27.2
224.20
236.30
e9/l
7.83
1012
10409
1037
10660
0.87
1.28
45.9
27.1
91.79
91.74
fl
0.14
1024
10499
830
7937
1.13
1.28
39.1
22.0
14.24
13.81
%
14.63
820
7825
73
573
1.29
1.27
2.5
2.4
—
—
—
0
0
21
130
1.63
1.27
1.7
2.4
—
—
—
0
0
386
4203
0.88
1.25
4.9
3.9
0.03
0.03
estimate
0.01
112
1022
9
45
2.01
1.23
1.2
1.2
—
—
—
0
0
1038
10663
0.87
1.23
45.9
27.2
7.29
6.86
e9/l
8.09
1012
10376
10
49
2.05
1.22
1.4
1.6
—
—
—
0
0
931
9625
0.89
1.20
5.3
5.2
1.29
1.40
mmol/l
15.40
846
8760
18
110
1.65
1.15
1.2
1.1
—
—
—
0
0
5
113
0.44
1.13
1.0
1.2
—
—
—
0
0
13
73
1.79
1.11
1.1
1.1
—
—
—
0
0
46
604
0.75
1.10
1.2
1.3
—
—
—
0
0
7
140
0.50
1.09
1.3
1.1
—
38.92
—
0
23
102
853
1.21
1.06
4.9
3.8
—
—
—
0
0
942
9706
0.89
1.04
5.4
5.3
4.16
4.41
mmol/l
12.35
865
8920
32
230
1.40
1.02
1.1
1.2
—
—
—
0
0
16
99
1.62
1.00
1.5
1.3
—
—
nmol/l
—
0
0
0
30
0.00
0.97
0.0
2.0
—
—
—
0
0
943
9701
0.90
0.96
5.3
5.5
5.93
6.09
mmol/l
5.08
856
8745
1016
9897
1.12
0.95
32.9
17.9
40.70
27.99
mg/l
22.36
936
8368
13
77
1.70
0.95
1.8
2.7
16.09
16.30
%
0.08
13
77
6
27
2.23
0.93
1.8
1.6
66.25
88.04
nmol/24h
—
6
27
42
322
1.31
0.92
1.5
1.4
208.87
278.61
ug/g
1.52
22
197
261
2377
1.12
0.92
2.9
3.1
2.46
2.45
mmol/l
0.12
221
2128
227
2505
0.89
0.91
4.6
4.1
1.02
1.02
kg/l
0.02
163
1684
103
1202
0.84
0.90
2.0
2.4
12.29
13.33
nmol/l
0.62
88
1069
8
42
1.91
0.88
2.0
2.4
1736.25
2123.86
ml
—
8
35
71
585
1.23
0.88
3.3
3.6
1.02
1.02
ratio
0.29
58
539
10
169
0.59
0.88
1.2
1.4
—
—
—
0
0
39
298
1.32
0.88
1.7
1.6
24.41
21.49
u/ml
—
7
58
13
79
1.65
0.88
1.1
1.4
—
—
—
0
0
12
72
1.67
0.85
2.7
1.5
90.67
89.42
umol/l
0.05
12
72
29
389
0.74
0.85
1.2
1.2
—
—
—
0
0
303
2802
1.11
0.81
3.3
3.1
0.20
0.06
—
5
100
10
58
1.73
0.79
1.4
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.0
—
2.21
—
0
12
11
67
1.65
0.75
1.4
1.1
—
—
—
0
0
1020
10410
0.91
0.75
15.8
12.5
25.21
26.15
u/l
0.92
984
10056
81
693
1.18
0.72
1.1
1.1
—
—
—
0
0
483
4590
1.08
0.71
2.4
2.3
78.41
78.42
nmol/l
0.00
426
4043
63
528
1.20
0.70
1.3
1.4
—
—
—
0
0
317
3385
0.92
0.69
3.2
3.5
0.86
0.80
ug/l
0.16
232
2317
117
1319
0.88
0.68
3.0
3.1
4.53
4.98
e9/l
0.42
94
1120
5
27
1.85
0.68
2.0
1.3
11.74
7.02
mmol/l
—
5
27
117
1038
1.14
0.66
2.4
2.1
0.00
0.01
estimate
0.50
24
204
11
70
1.58
0.65
1.1
1.3
104.18
159.08
pmol/l
0.95
11
70
7
44
1.59
0.65
3.4
3.5
—
—
—
0
0
10
62
1.62
0.65
1.1
1.0
—
—
—
0
0
111
983
1.14
0.64
3.9
4.7
0.14
0.16
%
0.03
38
299
117
1040
1.14
0.64
3.1
2.4
0.29
0.49
e6/l
0.98
111
1000
5
29
1.73
0.64
1.0
1.0
—
—
—
0
0
117
1041
1.14
0.64
2.6
2.4
206.53
151.15
ug/g
0.47
98
841
275
2943
0.92
0.63
4.6
3.4
2.50
0.06
estimate
0.49
101
927
102
1152
0.88
0.63
6.4
4.5
7.31
7.36
ph
0.62
75
825
11
164
0.67
0.61
1.4
2.0
—
—
—
0
0
1038
10558
0.92
0.61
42.0
24.1
95.67
85.28
umol/l
7.31
1024
10410
9
139
0.65
0.60
1.2
1.2
—
—
—
0
0
28
218
1.29
0.60
1.6
2.3
0.79
0.90
%
0.54
17
168
973
9921
0.92
0.60
6.1
6.1
2.38
2.56
mmol/l
9.01
889
9062
0
22
0.00
0.59
0.0
1.0
—
0.31
—
0
6
10
64
1.57
0.58
2.5
1.7
123.92
109.88
ng/l
—
10
64
0
23
0.00
0.58
0.0
1.0
—
0.36
—
0
7
904
9235
0.93
0.57
4.7
4.4
1.35
1.28
mmol/l
2.27
815
8321
8
125
0.64
0.54
1.4
3.1
—
—
—
0
0
108
969
1.12
0.54
3.2
4.3
0.43
0.70
%
1.27
42
341
6
39
1.54
0.53
2.0
2.7
0.66
0.60
mmol/l
—
6
39
16
215
0.74
0.52
1.1
1.2
1.42
1.50
g/l
0.47
16
215
9
63
1.43
0.52
1.3
1.7
—
—
—
0
0
6
40
1.50
0.51
3.2
1.4
—
—
—
0
0
37
306
1.22
0.51
1.4
1.6
6518.25
16191.21
e6/l
1.41
24
206
583
5636
1.06
0.50
4.6
3.9
0.00
2.83
estimate
0.80
141
1240
574
5554
1.06
0.47
4.6
3.9
0.00
0.00
estimate
-0.00
137
1219
52
448
1.17
0.47
1.1
1.2
179.33
138.66
u/ml
0.20
20
166
7
49
1.43
0.46
3.4
3.3
—
—
—
0
0
18
230
0.78
0.43
1.2
1.3
0.97
0.91
g/l
0.43
18
230
128
1177
1.10
0.43
1.5
1.4
—
—
—
0
0
809
7920
1.06
0.43
41.2
23.5
329.79
332.45
g/l
13.18
801
7863
893
9090
0.94
0.43
5.1
4.9
2.00
2.02
mu/l
0.15
813
8240
583
5659
1.05
0.42
4.7
3.9
0.00
0.27
estimate
0.53
135
1164
18
140
1.29
0.42
2.3
4.6
—
—
—
0
0
8
58
1.38
0.41
1.3
1.6
—
—
—
0
0
5
33
1.52
0.41
1.4
1.5
2.28
1.67
umol/l
—
5
28
0
17
0.00
0.40
0.0
1.0
—
4.95
—
0
9
0
18
0.00
0.40
0.0
7.6
—
8.29
—
0
18
156
1455
1.08
0.39
1.3
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
2.6
—
1.89
—
0
19
5
36
1.39
0.38
1.0
1.1
—
99.00
—
0
8
71
638
1.12
0.38
1.8
1.8
1.24
1.53
g/l
0.55
66
579
992
10054
0.94
0.38
27.6
16.1
—
—
—
0
0
94
859
1.10
0.37
2.6
2.8
5.96
6.07
ph
0.45
63
623
105
965
1.10
0.37
3.6
4.6
0.06
0.11
%
0.61
36
307
17
212
0.80
0.35
1.1
1.2
—
—
—
0
0
14
179
0.78
0.35
1.3
1.9
—
—
—
0
0
14
179
0.78
0.35
1.2
1.9
—
—
—
0
0
5
80
0.62
0.35
1.2
2.6
—
—
—
0
0
110
1018
1.09
0.34
3.5
4.5
0.79
0.81
%
0.04
41
355
14
178
0.78
0.34
1.3
1.8
—
—
—
0
0
205
2160
0.94
0.34
5.3
4.7
—
—
—
0
0
10
133
0.75
0.33
1.4
2.0
—
—
—
0
0
46
519
0.88
0.33
1.9
1.9
—
—
—
0
0
14
177
0.79
0.33
1.3
2.0
—
—
—
0
0
376
3891
0.95
0.33
3.2
3.4
81.69
44.24
mg/l
2.20
265
2591
372
3596
1.05
0.31
1.8
1.8
17.88
20.24
nmol/l
2.79
321
3026
44
390
1.13
0.31
1.5
1.7
0.39
0.37
mg/l
0.06
22
193
7
54
1.30
0.30
1.3
1.0
—
—
—
0
0
7
54
1.30
0.30
1.1
1.1
112.57
365.24
u/l
—
7
49
729
7421
0.96
0.30
4.1
3.8
15.32
15.01
pmol/l
2.49
656
6677
11
84
1.31
0.30
1.1
1.2
—
—
—
0
0
7
55
1.27
0.30
1.1
1.1
—
—
—
0
0
187
1778
1.06
0.30
1.4
1.5
2.75
2.81
g/l
0.15
95
1054
413
4010
1.04
0.29
2.5
2.3
—
—
—
0
0
21
176
1.20
0.29
4.2
3.1
4.76
4.54
e9/l
0.10
21
176
8
110
0.73
0.29
1.1
1.3
—
—
—
0
0
54
488
1.11
0.28
2.5
3.6
1050.28
8382.65
u/ml
0.70
46
419
22
259
0.85
0.28
5.4
3.3
32.09
29.02
mg/l
0.17
17
186
9
75
1.20
0.25
1.0
1.1
107.89
104.71
pmol/l
—
9
75
27
308
0.87
0.24
4.1
4.3
—
—
—
0
0
37
331
1.12
0.24
3.2
3.0
1.58
1.66
mmol/l
0.21
37
322
125
1319
0.94
0.24
3.8
4.3
5.66
22.49
ug/l
1.84
96
1102
100
940
1.07
0.24
2.2
2.2
389.08
386.66
nmol/l
0.04
93
870
27
306
0.88
0.23
1.9
3.5
66.89
83.67
u/ml
0.18
27
298
389
3987
0.97
0.22
3.7
4.1
17.40
8.30
mg/mmol
1.92
258
2566
14
116
1.21
0.22
1.6
1.2
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
172.40
195.82
mmol/24h
—
5
41
0
10
0.00
0.21
0.0
4.5
—
12.20
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
67.30
—
0
10
0
12
0.00
0.21
0.0
1.2
—
2.01
—
0
12
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
5
43
1.16
0.21
1.0
1.3
154.48
114.72
nmol/l
—
5
29
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
100
947
1.06
0.20
1.4
1.4
—
—
—
0
0
6
48
1.25
0.20
1.0
1.3
4.57
9.25
ug/l
—
6
42
6
48
1.25
0.20
1.3
1.1
—
—
—
0
0
154
1604
0.95
0.20
1.4
1.3
29.83
39.54
iu/ml
0.77
53
496
31
279
1.11
0.19
2.2
2.3
275.19
66.54
ug/min
1.23
20
163
14
119
1.18
0.17
1.1
1.2
—
—
—
0
0
51
475
1.08
0.17
1.4
1.3
—
—
—
0
0
5
70
0.71
0.16
1.0
1.1
148.36
142.91
nmol/l
—
5
70
390
3976
0.97
0.16
3.1
3.4
6.85
7.77
mmol/l
4.67
322
3305
144
1489
0.96
0.14
1.4
1.3
21.31
12.36
u/ml
0.52
43
533
635
6423
0.98
0.14
3.6
3.4
66.12
55.48
u/l
1.63
590
5954
14
122
1.15
0.13
2.7
1.5
39.61
37.26
ng/l
0.04
14
122
34
366
0.93
0.13
1.5
1.9
43.35
41.46
nmol/l
0.26
34
352
52
491
1.06
0.13
1.2
1.2
—
—
—
0
0
14
123
1.14
0.12
1.9
1.8
—
1504.00
—
0
5
40
376
1.07
0.11
1.1
1.1
—
—
—
0
0
249
2539
0.98
0.11
1.8
1.8
103431787.70
19639040.19
pmol/l
0.58
204
2103
13
147
0.88
0.11
1.1
1.3
—
—
—
0
0
57
543
1.05
0.11
1.2
1.3
271.71
196.51
u/ml
0.24
50
502
15
134
1.12
0.11
1.3
1.1
—
—
—
0
0
5
44
1.14
0.10
3.0
1.7
93.74
55.26
ug/l
—
5
44
15
135
1.11
0.09
1.3
1.1
—
—
—
0
0
26
242
1.08
0.09
1.0
1.3
80.81
61.84
mmol/l
1.57
21
199
5
47
1.06
0.09
1.0
1.7
39.06
40.06
g/l
—
5
47
18
165
1.09
0.08
1.1
1.1
—
—
—
0
0
28
297
0.94
0.08
1.2
1.1
—
—
—
0
0
28
297
0.94
0.08
1.4
1.2
—
1005.71
—
0
7
8
77
1.04
0.07
1.0
1.1
—
—
—
0
0
8
77
1.04
0.07
1.3
1.1
—
—
—
0
0
34
324
1.05
0.07
15.1
11.3
—
—
—
0
0
29
275
1.06
0.06
3.2
3.2
6.82
7.65
mmol/l
1.45
29
268
25
236
1.06
0.06
1.2
1.1
—
—
—
0
0
10
90
1.11
0.05
1.1
1.6
—
—
—
0
0
197
1948
1.01
0.04
1.3
1.2
5.80
1.76
u/ml
0.61
39
504
25
239
1.05
0.04
1.6
1.6
—
—
—
0
0
18
170
1.06
0.04
1.1
1.1
—
—
—
0
0
407
4092
0.99
0.03
5.0
3.8
—
0.62
—
0
13
97
960
1.01
0.02
4.4
3.4
1.21
1.22
mmol/l
0.79
83
834
319
3200
1.00
0.01
5.1
4.0
0.03
0.01
estimate
0.36
116
1076
22
226
0.97
0.00
4.1
3.0
59.68
59.15
%
0.07
22
226
1035
10357
1.00
0.00
41.6
22.0
4.01
4.01
mmol/l
0.07
1020
10131
25
246
1.02
0.00
1.2
1.3
46.01
38.54
u/l
0.12
18
217
94
938
1.00
0.00
1.6
1.5
—
—
—
0
0
529
5294
1.00
0.00
2.4
2.2
89.07
93.82
pmol/l
1.58
290
2887
1034
10342
1.00
0.00
41.6
21.8
139.28
139.66
mmol/l
5.03
1019
10136
11
107
1.03
0.00
1.6
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
402.00
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
0.52
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
0.02
—
0
9
0
7
0.00
-0.00
0.0
1.6
—
7.83
—
0
7
0
8
0.00
-0.00
0.0
4.0
—
—
—
0
0
63
630
1.00
-0.00
2.2
2.6
10.62
14.49
au/ml
—
5
44
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
11
110
1.00
-0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
8
89
0.90
-0.00
1.5
1.2
—
—
—
0
0
54
540
1.00
-0.00
2.7
2.1
0.00
1.67
estimate
0.50
20
150
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
78
0.90
-0.00
3.4
2.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint I9_AORTDIS and mortality.

Females

Parameter HR [95% CI] p-value
I9_AORTDIS 2.063 [1.73, 2.46] < 0.001
Birth year 0.998 [0.99, 1.01] 0.644

During the follow-up period (1.1.1998 — 31.12.2019), 517 out of 1366 females with I9_AORTDIS died.

Males

Parameter HR [95% CI] p-value
I9_AORTDIS 1.802 [1.59, 2.04] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 1145 out of 3086 males with I9_AORTDIS died.

Mortality risk

Mortality risk for people of age

years, who have I9_AORTDIS.

N-year risk Females Males
1 0.165% 0.341%
5 1.303% 1.92%
10 3.107% 5.296%
15 5.893% 9.595%
20 10.804% 16.203%

Relationships between endpoints

Index endpoint: I9_AORTDIS – Dissection of aorta

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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