Brain glioblastoma

C3_GBM

brain glioblastoma: A WHO grade IV malignant astrocytic tumor that arises from the brain, usually the cerebral hemispheres. It is characterized by the presence of poorly differentiated astrocytes, cellular polymorphism, nuclear atypia, and increased mitotic activity. The prognosis is poor.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • HLP_C3_GBM
588

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C71
  • Cause of death: ICD-9 191
  • Cause of death: ICD-8 191
  • Cancer registry: Topography ICD-O-3 C71
  • Cancer registry: Morphology ICD-O-3 9440
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

588

4. Check minimum number of events

None

588

5. Include endpoints

588

6. Filter based on genotype QC (FinnGen only)

518

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE
Control conditions
not HLP_C3_GBM

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 518 206 312
Unadjusted period prevalence (%) 0.12 0.07 0.14
Median age at first event (years) 65.75 66.29 65.39

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
550
Matched controls
5500
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB02
ATC
dexamethasone; systemic
1890.8
307.7
486
22
N03AX14
ATC
levetiracetam; systemic
118.9
307.7
305
57
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
62.5
307.7
208
53
Z51.5
ICD-10 Finland
Palliative care
58.3
307.7
291
104
A03FA01
ATC
metoclopramide; systemic, rectal
27.2
307.7
356
348
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
36.9
307.7
266
136
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
2302.5
307.7
401
6
L01AX03
ATC
temozolomide; systemic
+∞
307.7
378
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
40.2
307.7
323
188
130
Kela drug reimbursment
Malignant tumour
+∞
307.7
433
*
A04AA01
ATC
ondansetron; systemic, rectal
46.2
281.8
175
55
WF002
NOMESCO Finland
Radical radiotherapy
1423.9
271.0
242
*
XX3DW
NOMESCO Finland
Time consuming IT work
27.4
256.1
195
108
ZXC95
NOMESCO Finland
Use of surgical navigator
85.7
254.1
136
21
A04AA02
ATC
granisetron; systemic, transdermal
3937.7
243.5
217
*
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
673.8
230.2
212
5
C71.23
ICD-10 Finland
Malignant tumor of temporal lobe grade IV glioma
+∞
221.2
197
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
31.9
195.7
134
55
C71.2
ICD-10 Finland
Malignant neoplasm: Temporal lobe
+∞
188.7
170
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
185.2
167
*
9440/3-C71.9
ICD-O-3
Glioblastoma, NOS, of brain, NOS
+∞
181.6
164
*
C71.13
ICD-10 Finland
Malignant tumor of frontal lobe grade IV glioma
+∞
174.5
158
*
9440/3-C71.2
ICD-O-3
Glioblastoma, NOS, of temporal lobe
+∞
158.2
144
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
30.7
153.7
105
42
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
152.4
139
*
C71.1
ICD-10 Finland
Malignant neoplasm: Frontal lobe
+∞
151.2
138
*
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
914.3
147.3
138
*
N03AX18
ATC
lacosamide; systemic
57.5
138.6
79
16
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
+∞
132.8
122
*
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
+∞
129.4
119
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
127.1
117
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
22.3
123.1
95
51
9440/3-C71.1
ICD-O-3
Glioblastoma, NOS, of frontal lobe
+∞
120.3
111
*
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
+∞
109.1
101
*
AA1AD
NOMESCO Finland
CT of head and brain
6.6
106.3
354
1182
C71.33
ICD-10 Finland
Malignant tumor of parietal lobe grade IV glioma
+∞
104.6
97
*
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
+∞
104.6
97
*
WX882
NOMESCO Finland
High dependency care
19.8
102.6
83
49
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
308.4
102.5
101
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
10.9
96.5
115
130
N05CD08
ATC
midazolam; nasal, systemic
17.1
87.8
76
51
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
84.6
79
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
931.8
83.8
80
*
N02AA05
ATC
oxycodone; systemic
6.0
83.5
197
468
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
891.0
80.5
77
*
C71.3
ICD-10 Finland
Malignant neoplasm: Parietal lobe
+∞
79.1
74
*
N03AF02
ATC
oxcarbazepine; oral
12.8
77.9
80
72
C71.30
ICD-10 Finland
Malignant tumor in parietal lobe without histology
+∞
74.7
70
*
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
402.3
72.5
71
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
5.3
71.1
194
516
9440/3-C71.3
ICD-O-3
Glioblastoma, NOS, of parietal lobe
+∞
68.2
64
*
C71.83
ICD-10 Finland
Overall malignant tumor of the brain grade IV glioma
+∞
64.9
61
*
N74
ICPC
Malignant neoplasm nervous system
694.8
64.2
62
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
7.9
64.1
97
145
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
344.8
61.7
61
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
17.3
61.4
52
33
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.7
61.3
137
303
C71.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of brain
+∞
57.3
54
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
57.3
54
*
WZC00
NOMESCO Finland
Treatment plan or consultation
4.0
56.7
264
1026
JN4AD
NOMESCO Finland
Body CT examination
6.9
55.3
95
162
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
582.6
54.5
53
*
WZC30
NOMESCO Finland
Teaching
4.8
54.1
152
405
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
203.2
54.0
55
*
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
558.2
52.4
51
*
ZXM40
NOMESCO Finland
Use of fluorescent substance
534.0
50.2
49
*
WX402
NOMESCO Finland
General anaesthesia
4.0
48.3
184
611
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
46.5
44
*
C71.99
ICD-10 Finland
Malignant tumor in unspecified localization in the brain other or unspecified histology
+∞
45.4
43
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
7.2
41.8
66
102
ZXC40
NOMESCO Finland
Use of ultrasound
58.2
41.2
48
9
A79
ICPC
Malignancy NOS
+∞
41.2
39
*
R4120
NOMESCO Finland
Occupational therapy
5.8
40.2
81
160
ZX070
NOMESCO Finland
Intensity modified radiotherapy
404.2
38.5
38
*
JN4BD
NOMESCO Finland
Extensive body CT
6.4
38.2
68
119
A28
ICPC
Limited function/disability NOS
3.5
38.1
174
640
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
38.0
36
*
C71.93
ICD-10 Finland
Malignant tumor in an unspecified localization in the brain grade IV glioma
+∞
36.9
35
*
A02BC02
ATC
pantoprazole; systemic
4.0
35.7
456
3023
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
9.0
35.2
45
54
C71.80
ICD-10 Finland
Overall malignant tumor of the brain without histology
+∞
33.7
32
*
C71.43
ICD-10 Finland
Malignant tumor of the occipital lobe grade IV glioma
+∞
33.7
32
*
C71.29
ICD-10 Finland
Malignant tumor in temporal lobe other or unspecified histology
+∞
33.7
32
*
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
32.6
31
*
WX872
NOMESCO Finland
Intensive care
5.1
32.6
74
162
ZXE20
NOMESCO Finland
More than three and less than five hours
3.7
31.2
116
369
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
54.8
30.7
36
7
A98
ICPC
Health maint/preventive medicine
0.3
30.4
396
4905
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.1
30.2
166
672
ZX090
NOMESCO Finland
Other technic of radiotherapy
84.9
29.1
32
*
C71.9
ICD-10 Finland
Malignant neoplasm: Brain, unspecified
+∞
28.4
27
*
H53.4
ICD-10 Finland
Visual field defects
8.4
27.6
37
47
N05CF01
ATC
zopiclone; oral
2.6
26.5
239
1242
B01AB10
ATC
tinzaparin; parenteral
4.0
26.0
82
231
R4110
NOMESCO Finland
Physiotherapy
2.7
25.3
192
912
N76
ICPC
Neoplasm nervous system unspecified
+∞
25.2
24
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
8.5
25.0
33
41
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
261.4
24.9
25
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
21.3
24.6
36
18
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.0
24.6
129
503
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
24.1
23
*
9440/3-C71.0
ICD-O-3
Glioblastoma, NOS, of cerebrum
+∞
24.1
23
*
C71.40
ICD-10 Finland
Malignant tumor of the occipital lobe without histology
+∞
24.1
23
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
23.7
163
733
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
+∞
23.1
22
*
R90.0
ICD-10 Finland
Intracranial space-occupying lesion
+∞
23.1
22
*
C71.00
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles without histology
+∞
23.1
22
*
G40.10
ICD-10 Finland
Simple partial seizures
42.1
22.9
28
7
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
87.2
22.9
25
*
N03AB02
ATC
phenytoin; systemic
9.4
22.2
27
30
H02AB04
ATC
methylprednisolone; systemic
3.0
22.0
118
463
C71.03
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade IV glioma
+∞
22.0
21
*
C71.19
ICD-10 Finland
Malignant tumor of frontal lobe other or unspecified histology
+∞
22.0
21
*
C71.4
ICD-10 Finland
Malignant neoplasm: Occipital lobe
+∞
22.0
21
*
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
228.7
21.8
22
*
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
18.4
21.6
33
19
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.2
21.5
23
1191
WW200, ,
SPAT
0.2
21.4
30
1287
9440/3-C71.8
ICD-O-3
Glioblastoma, NOS, of overlapping lesion of brain
+∞
21.0
20
*
WX704
NOMESCO Finland
Intubation
3.9
20.2
64
180
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
+∞
19.9
19
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
19.9
153
720
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
22.6
19.7
28
13
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
8.2
19.3
26
33
9440/3-C71.4
ICD-O-3
Glioblastoma, NOS, of occipital lobe
+∞
18.9
18
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
19.6
18.8
28
15
WF049
NOMESCO Finland
Radiotherapy of metastasis
196.4
18.6
19
*
G41.9
ICD-10 Finland
Status epilepticus, unspecified
26.1
18.4
25
10
XA800
NOMESCO Finland
Neuropsychological investigation
4.6
18.1
44
101
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
17.8
17
*
C71.22
ICD-10 Finland
Malignant tumor of temporal lobe grade III glioma
+∞
17.8
17
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
185.7
17.6
18
*
EB1VA, ,
NOMESCO Finland
0.1
16.9
9
639
115
Kela drug reimbursment
Breast cancer
+∞
16.7
16
*
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
6.9
16.7
26
39
N05BA04
ATC
oxazepam; oral
2.3
16.1
169
903
C10AA07
ATC
rosuvastatin; oral
0.3
15.4
66
1551
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
12.9
15.0
26
21
N05BA09
ATC
clobazam; oral
21.8
14.8
21
10
GD1AA, ,
SPAT
0.1
14.7
6
518
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
14.6
14
*
C71.0
ICD-10 Finland
Malignant neoplasm: Cerebrum, except lobes and ventricles
+∞
14.6
14
*
A10AB05
ATC
insulin aspart; parenteral
3.1
14.5
64
223
WZC00, ,
SPAT
0.1
14.3
6
506
R4130
NOMESCO Finland
Speech therapy
5.3
14.3
29
57
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
14.1
81
326
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
15.2
13.7
22
15
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
13.6
13
*
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
+∞
13.6
13
*
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
14.3
13.3
22
16
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.7
13.2
31
69
N03AG01
ATC
valproic acid; systemic, rectal
3.3
13.0
51
165
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.6
12.9
44
130
C71.39
ICD-10 Finland
Malignant tumor of parietal lobe other or unspecified histology
+∞
12.5
12
*
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
27.4
12.1
16
6
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
12.0
209
1323
WX110
NOMESCO Finland
Infiltration anesthesia
2.0
12.0
388
3006
M79.6
ICD-10 Finland
Pain in limb
0.5
11.6
98
1782
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
+∞
11.5
11
*
C71.21
ICD-10 Finland
Malignant tumor of temporal lobe grade II glioma
+∞
11.5
11
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
11.5
11
*
C71
ICD-10 Finland
Malignant neoplasm of brain
+∞
11.5
11
*
G93.6
ICD-10 Finland
Cerebral oedema
+∞
11.5
11
*
N05BA06
ATC
lorazepam; systemic, sublingual
3.3
11.4
43
136
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
35.8
11.3
14
*
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
5.7
11.2
21
38
OAB42, ,
SPAT
0.2
11.2
8
468
C10AX09
ATC
ezetimibe; oral
0.2
10.6
21
770
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.0
10.5
30
78
TPH07
NOMESCO Finland
Cathetrisation of artery
2.5
10.5
71
309
L02BA01
ATC
tamoxifen; oral
112.1
10.5
11
*
D69.5
ICD-10 Finland
Secondary thrombocytopenia
+∞
10.4
10
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
10.4
10
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
10.4
10
*
C71.32
ICD-10 Finland
Malignant tumor of parietal lobe grade III glioma
+∞
10.4
10
*
WPA15
NOMESCO Finland
Palliative care consultation with the patient and loved ones
33.2
10.4
13
*
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
0.4
10.3
48
1126
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
10.2
103
532
Z76.0
ICD-10 Finland
Issue of repeat prescription
0.3
10.2
38
988
WX725
NOMESCO Finland
Noninvasive ventilation
3.1
10.1
43
146
M25.5
ICD-10 Finland
Pain in joint
0.4
9.9
61
1273
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.4
9.9
42
1030
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.6
9.9
33
96
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
56.0
9.7
11
*
WZC30, ,
SPAT
0.1
9.7
*
320
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
9.6
50
190
R93.0
ICD-10 Finland
Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
101.7
9.4
10
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
9.4
9
*
C71.50
ICD-10 Finland
Malignant tumor of cerebral ventricle without histology
+∞
9.4
9
*
C71.01
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade II glioma
+∞
9.4
9
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
9.4
9
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
0.5
9.3
102
1729
R47.0
ICD-10 Finland
Dysphasia and aphasia
7.5
9.3
21
29
TKC20
NOMESCO Finland
Catheterisation of bladder
2.8
9.3
49
188
Z02.4
ICD-10 Finland
Examination for driving licence
0.4
9.2
67
1312
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
9.1
187
1225
WX892
NOMESCO Finland
Monitored bed care
2.6
9.0
56
234
HAB40
NOMESCO Finland
Wedge excision of mammary gland
19.0
9.0
13
7
L03
ICPC
Low back symptom/complaint
0.4
8.8
48
1061
L17
ICPC
Foot/toe symptom/complaint
0.4
8.8
59
1198
EB4VA, ,
NOMESCO Finland
0.2
8.8
10
528
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
11.8
8.6
15
13
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
91.4
8.4
9
*
G41.2
ICD-10 Finland
Complex partial status epilepticus
91.4
8.4
9
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
8.4
8
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
8.4
8
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
8.4
8
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
8.4
8
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
0.5
8.3
71
1319
B01AB05
ATC
enoxaparin; parenteral
1.8
8.1
160
1029
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
8.0
47
191
SAA02
NOMESCO Finland
Basic examination of mouth
0.6
7.9
202
2727
R41.0
ICD-10 Finland
Disorientation, unspecified
3.3
7.9
29
90
OAB44, ,
SPAT
0.1
7.9
5
318
C07AB07
ATC
bisoprolol; oral
0.6
7.9
158
2271
M75.1
ICD-10 Finland
Rotator cuff syndrome
0.4
7.8
52
1065
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
0.4
7.8
30
778
H02AB09
ATC
hydrocortisone; systemic
6.1
7.7
20
34
SPAT1109
SPAT
Analgesia with portable analgesic pump
45.6
7.7
9
*
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.0
7.7
33
113
Z71.8
ICD-10 Finland
Other specified counselling
0.5
7.7
62
1182
XX2RW, ,
NOMESCO Finland
12.1
7.6
13
11
C10AA05
ATC
atorvastatin; oral
0.6
7.6
133
1990
L03AA02
ATC
filgrastim; parenteral
81.1
7.4
8
*
XA400
NOMESCO Finland
EEG
13.6
7.4
12
9
HA1AA
NOMESCO Finland
X-ray mammography
3.7
7.4
23
64
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
4.2
7.3
19
46
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
+∞
7.3
7
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
7.3
7
*
OAA41
NOMESCO Finland
Health check based on individual needs
+∞
7.3
7
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.4
7.3
48
990
R03BB04
ATC
tiotropium bromide; inhalant
0.2
7.2
9
374
R01AD59
ATC
mometasone, combinations; nasal
0.0
7.0
*
172
L02BG04
ATC
letrozole; oral
14.0
6.9
11
8
M54.4
ICD-10 Finland
Lumbago with sciatica
0.3
6.9
24
656
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
0.2
6.9
9
365
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
40.6
6.8
8
*
SFA10
NOMESCO Finland
One-surface restoration
0.6
6.7
160
2233
OAB43, ,
SPAT
0.4
6.7
39
846
PA6AD
NOMESCO Finland
CT of neck arteries
2.9
6.6
30
106
N03AX23
ATC
brivaracetam; systemic
12.4
6.6
11
9
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.4
6.6
25
656
H25.1
ICD-10 Finland
Senile nuclear cataract
0.5
6.6
60
1105
SAA01
NOMESCO Finland
Simple examination of mouth
0.6
6.4
250
3127
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
70.6
6.4
7
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
70.6
6.4
7
*
SPAT1290
SPAT
Preparation of deceased person
70.6
6.4
7
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
70.6
6.4
7
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
14.5
6.4
10
7
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.0
6.4
28
97
SFA30
NOMESCO Finland
Three-surface restoration
0.6
6.3
122
1802
WPB10
NOMESCO Finland
Making a convalescent care decision
18.3
6.3
9
5
D19
ICPC
Teeth/gum symptom/complaint
0.5
6.3
61
1101
1CD02, ,
NOMESCO Finland
+∞
6.3
6
*
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
+∞
6.3
6
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
6.3
6
*
C71.49
ICD-10 Finland
Malignant tumor in occipital lobe other or unspecified histology
+∞
6.3
6
*
Z01.2
ICD-10 Finland
Dental examination
0.6
6.2
115
1720
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.1
6.2
*
183
SDA03
NOMESCO Finland
Periodontal treatment
0.6
6.2
97
1515
L13
ICPC
Hip symptom/complaint
0.4
6.1
33
739
N06DX01
ATC
memantine; oral
0.2
6.0
*
249
N19
ICPC
Speech disorder
6.1
6.0
15
25
A10BA02
ATC
metformin; oral
0.5
6.0
74
1242

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
333
126
65.45
307.65
1.3
1.3
—
—
—
0
0
289
759
6.92
114.68
1.8
1.8
26.43
29.40
s
14.10
280
737
243
568
6.87
108.01
5.3
7.9
1.12
1.27
mmol/l
0.31
194
472
243
575
6.78
106.44
5.3
7.9
4.91
5.15
kpa
4.29
238
560
243
575
6.78
106.44
5.3
7.9
17.73
11.61
kpa
29.70
238
562
243
576
6.77
106.22
5.3
7.9
7.43
7.42
ph
1.24
163
336
361
1351
5.87
91.24
3.2
1.7
—
—
—
0
0
328
1318
4.69
70.72
2.1
2.1
—
—
—
0
0
274
1004
4.45
65.85
1.9
2.1
—
—
—
0
0
325
1441
4.07
57.79
10.2
5.6
—
—
—
0
0
53
52
11.17
48.25
1.6
1.1
—
—
—
0
0
260
1097
3.60
47.53
3.8
3.8
95.77
87.24
%
8.31
253
1071
365
1953
3.58
44.70
2.5
2.5
—
—
estimate
—
0
0
414
2411
3.90
44.08
18.3
6.8
4.93
4.31
e9/l
5.50
349
2107
64
92
7.74
43.29
1.7
1.1
—
—
—
0
0
369
2024
3.50
42.63
6.1
5.9
1.19
1.21
mmol/l
6.45
364
1843
50
2125
0.16
42.12
1.4
2.0
1.44
1.36
mmol/l
0.33
41
1785
318
1620
3.28
41.07
2.8
2.3
146.72
275.14
u/l
1.83
313
1522
345
4696
0.29
40.98
3.4
5.6
4.81
4.56
mmol/l
4.08
314
4375
45
46
10.57
39.70
1.6
1.0
—
—
—
0
0
358
4763
0.29
39.51
3.7
6.4
2.93
2.66
mmol/l
5.14
326
4432
364
2045
3.31
39.06
10.2
5.8
1.26
3.01
%
50.67
358
1913
364
2053
3.29
38.64
10.2
5.8
0.39
0.70
%
22.40
359
1920
345
4670
0.30
38.55
3.4
5.5
1.43
1.43
mmol/l
0.01
316
4330
326
4543
0.31
38.50
4.6
6.9
39.43
39.86
mmol/mol
0.39
303
4256
380
2291
3.13
34.10
7.0
6.3
1.20
1.21
mmol/l
3.01
347
1987
60
105
6.29
33.61
1.7
1.2
43.11
39.16
e6/l
0.04
45
85
60
106
6.23
33.28
1.8
1.3
4049.54
1782.07
e6/l
0.34
46
87
64
124
5.71
32.25
1.5
1.2
817.48
484.82
mg/l
1.74
64
118
348
4606
0.33
31.55
4.3
5.4
6.04
6.04
mmol/l
0.02
314
4230
240
1172
2.86
31.15
1.2
1.3
—
—
—
0
0
370
2270
2.92
30.78
10.3
5.7
0.55
0.59
e9/l
4.05
303
1967
370
2282
2.90
30.25
10.3
5.7
0.03
0.04
e9/l
16.74
302
1985
370
2309
2.84
29.08
10.5
5.7
1.33
1.85
e9/l
30.13
308
2040
374
2348
2.85
29.03
11.0
5.8
0.09
0.20
e9/l
47.52
304
2067
240
1210
2.74
28.79
3.3
4.1
—
—
—
0
0
118
404
3.45
28.18
5.2
7.7
—
—
—
0
0
338
4475
0.37
27.33
3.2
4.6
1.32
1.33
mmol/l
0.05
310
4118
36
47
8.13
26.22
1.9
1.2
—
—
—
0
0
257
1443
2.47
23.45
10.5
2.1
2.36
2.35
mmol/l
0.15
248
1269
334
2228
2.27
19.06
9.0
15.9
1.10
1.29
inr
11.12
299
1864
225
1322
2.19
17.09
3.3
3.2
7.41
7.40
ph
4.60
154
948
85
1823
0.37
16.59
3.0
3.5
82.88
43.76
mg/l
0.69
58
1171
292
1945
2.07
15.49
5.1
4.1
33.87
35.98
g/l
8.62
284
1808
95
1882
0.40
15.01
2.8
3.4
8.75
7.91
mmol/l
0.68
80
1597
341
4254
0.48
14.82
4.1
5.0
1.76
1.97
mu/l
2.79
314
3900
115
2096
0.43
14.70
1.8
2.4
72.65
77.91
nmol/l
1.25
108
1867
110
2028
0.43
14.37
2.3
3.0
202.83
136.99
ug/l
1.23
98
1883
59
199
3.20
14.06
2.0
2.4
161.62
560.34
ug/l
1.11
59
188
96
1854
0.42
13.97
3.6
4.1
12.40
7.77
mg/mmol
0.52
54
1170
76
301
2.77
13.62
6.2
6.2
—
—
—
0
0
433
3448
2.20
12.97
16.6
6.0
66.83
76.69
u/l
12.26
427
3221
99
1841
0.44
12.75
2.6
3.4
—
—
—
0
0
138
2267
0.48
12.62
1.8
2.1
92.56
96.21
pmol/l
0.49
73
1177
89
404
2.44
12.03
2.1
7.1
6.89
10.22
mmol/l
6.36
83
388
84
373
2.48
11.90
3.2
4.2
1.78
0.70
%
4.92
64
74
131
705
2.13
11.79
2.1
2.9
2.39
1.61
e6/l
0.59
60
339
68
1434
0.40
11.73
1.4
1.7
17.35
20.13
nmol/l
1.54
62
1212
265
3492
0.53
11.62
3.5
4.0
14.86
14.86
pmol/l
0.01
245
3183
198
1246
1.92
11.43
2.4
3.0
0.47
0.40
e6/l
0.20
140
909
199
1272
1.88
10.84
2.5
3.3
—
—
—
0
0
88
1612
0.46
10.30
2.0
3.1
495.86
1246.11
ng/l
8.62
76
1365
450
4991
0.46
10.27
40.9
21.5
7.52
6.69
e9/l
11.34
435
4866
450
4990
0.46
10.22
40.9
21.4
4.40
4.55
e12/l
10.00
435
4862
450
4987
0.46
10.06
41.1
21.4
227.21
243.08
e9/l
6.60
436
4874
15
9
17.10
9.92
1.1
1.6
34.20
25.22
%
—
15
9
88
434
2.22
9.75
1.7
1.7
279.01
368.95
nmol/l
4.15
80
403
28
815
0.31
9.29
1.1
1.3
14.22
9.65
u/ml
0.13
13
311
273
1985
1.75
9.29
18.0
10.0
0.00
0.00
e9/l
1.51
198
1649
14
9
15.91
9.07
1.1
1.6
6.14
3.67
%
—
14
9
75
360
2.25
8.84
3.2
4.0
1.40
0.46
%
1.50
56
76
211
1455
1.73
8.47
2.6
3.2
31.50
96.68
e6/l
0.73
150
1112
19
28
6.99
8.13
1.3
1.8
38.72
42.42
%
0.41
19
28
26
75
3.59
7.91
2.2
4.3
2.70
2.49
mmol/l
0.13
19
48
140
880
1.79
7.64
3.9
2.1
2.46
2.44
mmol/l
1.04
129
780
60
1147
0.46
7.44
3.2
3.9
1.02
1.02
kg/l
0.12
48
758
39
878
0.40
7.35
1.1
1.3
10.76
36.40
iu/ml
—
8
255
14
15
9.54
7.32
1.2
1.1
—
—
—
0
0
147
2116
0.58
7.13
3.6
4.0
2.01
1.81
ug/l
0.33
126
1915
49
993
0.44
7.07
1.3
1.3
1.28
1.68
u/ml
0.17
14
278
188
1313
1.66
6.90
13.1
4.8
—
—
—
0
0
150
990
1.71
6.81
3.0
4.1
54.89
580.87
ng/l
4.46
122
794
16
26
6.30
6.51
3.3
4.7
—
—
—
0
0
222
1644
1.59
6.29
3.0
3.8
39.18
90.16
e6/l
2.20
154
1158
9
348
0.25
6.26
1.3
1.9
3.41
3.47
mmol/l
—
9
269
68
361
2.01
6.16
3.5
4.3
0.17
0.10
%
0.55
48
63
127
1842
0.60
6.05
3.4
3.7
0.00
0.01
estimate
0.80
34
359
79
1285
0.55
5.72
2.1
2.3
338.37
358.65
umol/l
1.01
67
1114
9
310
0.28
5.08
1.0
1.3
82.89
288.45
u/ml
—
9
289
23
544
0.40
4.77
1.3
1.5
—
—
—
0
0
122
830
1.60
4.75
2.3
2.8
540.22
523.84
mosm/kgh2o
0.37
109
726
81
1238
0.59
4.50
2.5
2.8
0.56
0.71
ug/l
2.48
54
770
8
9
9.00
4.29
1.0
1.0
—
—
—
0
0
27
568
0.45
4.19
4.2
2.7
6.96
4.54
e9/l
0.42
27
492
93
1352
0.62
4.15
3.2
3.9
0.00
0.01
estimate
0.50
35
413
36
675
0.50
4.03
1.0
1.2
—
—
—
0
0
79
1184
0.61
3.99
1.6
2.3
3.13
2.80
mg/l
0.40
64
1007
67
1034
0.60
3.80
1.4
1.7
461.24
31324323.22
pmol/l
0.97
54
846
7
9
7.86
3.56
1.0
1.1
—
—
—
0
0
22
93
2.42
3.53
1.6
3.8
—
—
—
0
0
44
249
1.83
3.35
2.2
1.4
3.22
2.62
ug/l
0.40
27
186
110
1482
0.68
3.29
2.4
2.5
51.20
60.91
u/l
1.94
103
1368
75
500
1.58
3.15
1.9
2.3
4.86
7.40
umol/l
2.67
67
439
204
2449
0.73
3.02
3.0
3.8
0.00
0.00
estimate
-0.00
43
452
29
528
0.52
2.97
1.6
2.5
152.88
139.04
ug/g
0.11
24
424
63
411
1.60
2.91
3.0
3.5
7.41
7.34
ph
4.16
55
280
18
381
0.45
2.87
1.3
1.4
—
—
—
0
0
8
221
0.35
2.85
1.6
1.9
36.75
39.66
nmol/l
—
8
214
15
335
0.43
2.75
1.2
1.3
—
—
—
0
0
73
501
1.53
2.71
2.1
3.2
2.15
2.00
mmol/l
0.16
68
432
7
202
0.34
2.71
1.0
2.0
—
7.66
—
0
48
203
2409
0.75
2.66
3.0
3.8
0.00
0.00
estimate
-0.00
39
445
58
382
1.58
2.59
3.7
4.4
0.08
0.00
%
0.74
38
62
57
838
0.64
2.58
1.2
1.3
2.38
2.77
g/l
0.56
32
514
5
7
7.20
2.55
1.0
1.0
—
—
—
0
0
161
1957
0.75
2.44
2.8
3.4
6.25
6.24
ph
0.07
81
1107
211
2466
0.77
2.39
3.0
3.8
0.00
0.02
estimate
0.93
39
424
21
105
2.04
2.34
2.1
1.8
15.07
60.47
u/ml
0.47
15
82
26
452
0.55
2.31
1.2
1.5
—
—
—
0
0
10
35
2.89
2.22
1.2
1.3
—
—
—
0
0
29
483
0.58
2.21
1.1
1.4
—
—
—
0
0
7
19
3.72
2.15
1.1
1.1
—
—
—
0
0
6
14
4.32
2.15
1.0
1.0
—
—
—
0
0
11
44
2.53
2.02
1.1
1.2
—
—
—
0
0
71
518
1.43
1.98
2.1
3.3
7.40
7.38
ph
1.76
37
306
100
1268
0.74
1.97
3.1
3.3
0.00
0.00
estimate
-0.00
30
343
11
47
2.37
1.78
1.0
1.2
—
—
—
0
0
0
46
0.00
1.71
0.0
1.2
—
1.20
—
0
26
7
163
0.42
1.69
8.3
10.9
—
—
—
0
0
11
49
2.27
1.64
1.0
1.7
12.77
10.19
%
0.70
11
49
10
42
2.41
1.62
1.3
1.4
0.84
1.22
promille
—
10
37
14
70
2.03
1.60
1.1
1.3
—
—
—
0
0
6
21
2.88
1.51
3.8
2.9
0.67
1.05
index
—
6
21
224
1980
1.22
1.50
3.7
3.9
17.40
104.88
ng/l
1.74
196
1482
14
251
0.55
1.44
1.1
1.1
—
—
—
0
0
21
336
0.61
1.42
1.0
1.2
—
—
—
0
0
119
987
1.26
1.42
6.3
4.2
—
—
—
0
0
6
137
0.43
1.42
1.5
1.6
—
—
—
0
0
318
3432
0.83
1.41
3.4
4.3
—
20203.40
—
0
5
27
403
0.65
1.36
3.5
2.3
0.86
0.30
e6/l
0.40
27
380
0
39
0.00
1.34
0.0
1.6
—
8.08
—
0
39
18
106
1.72
1.31
1.1
1.2
—
—
—
0
0
6
131
0.45
1.30
1.2
1.2
—
2.56
—
0
18
12
216
0.55
1.27
1.6
1.3
—
—
—
0
0
45
332
1.39
1.23
2.3
2.9
138.11
131.69
g/l
1.90
45
325
9
167
0.53
1.20
3.1
1.8
—
—
—
0
0
38
276
1.40
1.15
1.9
2.4
0.60
0.60
%
0.06
38
276
14
80
1.77
1.14
2.6
2.5
65.79
58.93
%
1.04
14
80
39
287
1.39
1.10
1.3
1.4
—
64.29
—
0
27
5
21
2.39
1.09
4.0
1.0
—
37.37
—
0
6
7
33
2.14
1.06
1.4
1.1
—
—
—
0
0
38
282
1.37
1.03
1.9
2.4
1.18
1.25
%
0.23
38
282
5
109
0.45
1.01
2.2
3.3
0.70
0.82
nmol/l
—
5
93
0
29
0.00
0.98
0.0
1.3
—
8.02
—
0
23
17
258
0.65
0.97
1.2
1.2
102.75
102.65
u/ml
—
6
110
67
815
0.80
0.97
1.5
1.7
849.75
1200.01
nmol/l
4.42
51
622
8
143
0.55
0.94
1.0
1.1
—
—
—
0
0
17
110
1.56
0.91
3.8
4.5
—
—
—
0
0
26
185
1.43
0.91
4.5
4.0
1.54
1.40
mmol/l
0.41
26
180
33
246
1.36
0.89
2.8
3.0
25.54
25.17
mmol/l
0.30
33
237
65
534
1.25
0.88
1.6
1.6
—
—
—
0
0
116
1012
1.19
0.86
2.5
2.5
6.21
4.83
e6/l
0.49
107
920
14
88
1.61
0.85
1.0
1.2
—
—
—
0
0
11
65
1.71
0.83
2.5
2.7
6.31
4.37
e9/l
0.70
11
65
6
32
1.88
0.82
1.0
1.1
—
—
—
0
0
16
106
1.52
0.79
4.2
3.4
2.18
1.23
index
0.42
11
57
0
26
0.00
0.78
0.0
1.1
—
214.52
—
0
26
0
26
0.00
0.78
0.0
1.2
—
—
—
0
0
23
313
0.72
0.77
1.2
1.3
—
—
—
0
0
9
54
1.68
0.75
1.0
1.3
—
—
—
0
0
9
54
1.68
0.75
1.0
1.3
—
—
—
0
0
9
54
1.68
0.75
1.0
1.3
—
—
—
0
0
9
54
1.68
0.75
1.0
1.3
—
—
—
0
0
5
24
2.09
0.74
2.8
2.5
—
—
—
0
0
169
1537
1.14
0.74
5.7
2.9
28.05
34.92
u/l
2.78
164
1446
11
171
0.64
0.73
1.2
1.2
—
1.00
—
0
11
16
109
1.48
0.71
1.2
1.2
—
—
—
0
0
19
261
0.72
0.69
1.1
1.5
—
—
—
0
0
5
95
0.52
0.67
1.2
2.0
3.83
4.86
mmol/24h
—
5
86
16
112
1.44
0.64
1.0
1.2
—
—
—
0
0
77
669
1.18
0.62
1.6
2.0
—
—
—
0
0
5
30
1.67
0.61
1.4
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
3.50
—
0
7
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
13
185
0.70
0.59
1.1
1.2
—
—
—
0
0
34
418
0.80
0.58
1.8
2.1
70.60
67.33
e9/l
0.18
22
317
40
329
1.23
0.58
2.6
2.9
1.23
1.22
mmol/l
0.40
40
273
16
115
1.40
0.57
1.0
1.2
—
—
—
0
0
8
55
1.46
0.56
1.4
1.1
—
—
—
0
0
9
61
1.48
0.54
3.9
2.3
1.18
1.18
mmol/l
—
9
61
16
117
1.38
0.53
1.0
1.2
—
—
—
0
0
16
117
1.38
0.53
1.0
1.2
—
—
—
0
0
9
63
1.44
0.52
3.9
2.2
102.22
105.73
mmol/l
—
9
63
9
63
1.44
0.52
3.9
2.2
4.12
4.09
mmol/l
—
9
63
37
306
1.22
0.52
3.0
3.6
—
—
—
0
0
11
75
1.48
0.51
1.0
1.5
—
—
—
0
0
41
344
1.21
0.50
1.1
1.1
—
—
—
0
0
47
401
1.19
0.49
1.8
2.2
31.73
46.05
u/l
0.63
41
323
14
187
0.74
0.46
1.7
1.3
—
—
—
0
0
10
139
0.71
0.42
2.4
2.2
183.60
105.84
ug/min
—
5
79
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
40.49
—
0
9
15
115
1.31
0.39
1.0
1.2
—
—
—
0
0
13
169
0.76
0.37
1.3
1.8
—
—
—
0
0
37
426
0.86
0.36
1.1
1.6
—
—
—
0
0
49
545
0.89
0.30
1.7
1.9
2.06
1.74
%
0.88
41
486
95
1019
0.92
0.30
1.6
1.7
3.19
1.13
mg/l
1.82
84
790
11
87
1.27
0.24
1.4
1.3
24.05
24.57
iu/l
0.02
11
72
5
39
1.28
0.23
1.4
1.2
20.72
23.70
ng/l
—
5
39
5
41
1.22
0.22
1.0
1.6
1340.40
1305.61
mg
—
5
41
0
11
0.00
0.21
0.0
2.5
—
0.00
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.69
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.76
—
0
6
27
303
0.89
0.21
1.2
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
3.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
7.35
—
0
7
0
13
0.00
0.21
0.0
3.4
—
37.50
—
0
5
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
8.8
—
5.34
—
0
14
0
14
0.00
0.20
0.0
2.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
17.59
—
0
14
0
14
0.00
0.20
0.0
3.0
—
117762.22
—
0
9
446
4509
0.94
0.19
28.4
14.0
17.89
24.24
mg/l
8.60
431
3613
11
130
0.84
0.16
1.4
1.1
—
—
—
0
0
8
72
1.11
0.16
1.3
1.2
—
—
—
0
0
6
78
0.77
0.15
1.2
1.1
—
—
—
0
0
12
139
0.86
0.14
1.3
1.3
20.19
33.27
mg/l
—
7
121
12
139
0.86
0.14
1.3
1.3
34.12
43.79
mg/l
—
6
121
8
100
0.80
0.13
1.0
1.4
4.82
6.65
u/l
—
8
82
315
3104
1.03
0.13
4.0
3.4
69.52
49.50
u/l
1.06
305
2918
20
180
1.12
0.13
2.0
3.9
25.04
25.10
mmol/l
0.05
20
167
11
94
1.17
0.13
1.0
1.1
—
—
—
0
0
5
45
1.11
0.10
1.8
2.4
—
—
—
0
0
5
46
1.09
0.09
2.6
2.3
—
—
—
0
0
11
124
0.88
0.09
1.2
2.3
11.75
11.14
mg/l
0.15
11
117
22
237
0.93
0.09
2.2
2.4
—
—
—
0
0
5
61
0.82
0.08
1.2
1.1
—
—
—
0
0
5
65
0.77
0.08
1.6
1.4
214.20
295.20
pmol/l
—
5
55
7
64
1.09
0.08
1.4
1.4
—
—
nmol/l
—
0
0
6
70
0.86
0.07
1.0
1.0
—
—
—
0
0
6
70
0.86
0.07
1.0
1.1
1.43
1.53
g/l
—
6
65
24
225
1.07
0.07
1.9
3.8
—
—
—
0
0
7
83
0.84
0.07
1.1
3.3
5.30
9.81
pmol/l
—
7
83
36
374
0.96
0.05
1.6
2.4
0.27
0.21
g/l
4.33
36
343
60
612
0.98
0.03
1.3
1.5
—
—
—
0
0
51
502
1.02
0.01
1.4
2.5
2.48
7.84
ug/l
8.27
43
448
57
578
0.98
0.01
1.2
1.7
—
—
—
0
0
36
355
1.02
0.00
2.9
2.6
6.39
6.04
ph
1.64
31
233
46
465
0.99
0.00
1.2
1.5
—
—
—
0
0
12
122
0.98
0.00
1.3
1.3
1.85
1.39
ratio
—
5
74
22
222
0.99
0.00
1.1
1.7
—
—
—
0
0
7
69
1.01
-0.00
1.3
1.3
32.73
83.95
mu/l
—
7
63
0
5
0.00
-0.00
0.0
1.6
—
349.16
—
0
5
6
65
0.92
-0.00
1.2
1.1
—
15.77
—
0
21
5
54
0.93
-0.00
1.2
1.8
40.80
36.93
u/ml
—
5
49
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
0.52
—
0
6
0
9
0.00
-0.00
0.0
6.3
—
7.61
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
76.00
—
0
8
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
2.09
—
0
7
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
0.02
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.2
—
9.50
—
0
6
6
59
1.02
-0.00
1.8
2.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_GBM – Brain glioblastoma

GWS hits: 3

This endpoint is excluded from FinRegistry analyses (omitted endpoint).