Crossbite

K11_CROSSBITE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.25
  • Hospital discharge: ICD-10 K07.25
  • Cause of death: ICD-10 K07.25

3 out of 7 registries used, show all original rules.

3556

4. Check minimum number of events

None

3556

5. Include endpoints

None

3556

6. Filter based on genotype QC (FinnGen only)

3147

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 107102 55446 51543
Only index persons 80238 41490 38748
Unadjusted period prevalence (%)
Whole population 1.52 1.59 1.44
Only index persons 1.50 1.53 1.48
Median age at first event (years)
Whole population 9.39 9.33 9.41
Only index persons 10.97 11.00 10.94

-FinnGen-

Key figures

All Female Male
Number of individuals 3147 1972 1175
Unadjusted period prevalence (%) 0.64 0.70 0.54
Median age at first event (years) 25.45 25.63 25.14

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3281
Matched controls
30190
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
EEC05
NOMESCO Finland
Le Fort I osteotomy
65.1
316.3
187
28
SAA04
NOMESCO Finland
Special examination of mouth
5.2
314.5
810
1800
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
57.1
307.7
284
50
K07.14
ICD-10 Finland
Retrognaty, maxillary
44.0
307.7
316
73
SJC10
NOMESCO Finland
Orthodontic band in one tooth
6.3
307.7
760
1375
K07.24
ICD-10 Finland
Open bite
11.3
307.7
395
361
EB1MA
NOMESCO Finland
Cephalometry with X-ray
5.8
307.7
845
1691
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
5.5
307.7
857
1814
SBB10
NOMESCO Finland
Dental impressions
6.5
307.7
1595
3845
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
6.3
307.7
915
1743
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
5.9
307.7
918
1873
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
6.1
307.7
753
1407
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
+∞
307.7
3281
*
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
5.4
307.7
901
1962
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
5.2
305.9
771
1679
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
5.4
287.4
674
1373
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
5.0
283.8
743
1664
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
6.7
246.7
438
678
SXC05
NOMESCO Finland
Other oral or dental procedure
3.9
246.4
981
2994
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
4.2
236.9
782
2081
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
4.4
221.3
682
1717
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
4.7
217.8
589
1337
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
3.7
216.6
914
2873
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.7
203.4
826
2520
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.1
202.2
2096
11044
SAA03
NOMESCO Finland
Extended examination of mouth
3.2
201.5
2345
13175
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
4.9
185.2
459
963
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
4.7
181.6
474
1038
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
3.8
172.6
639
1815
K07.10
ICD-10 Finland
Asymmetry of jaw
24.9
160.0
120
46
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.7
154.8
595
1725
WZC00
NOMESCO Finland
Treatment plan or consultation
2.6
152.7
1856
10061
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
16.2
134.5
121
71
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
23.0
132.3
102
42
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
4.1
130.2
404
1002
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
14.5
121.7
116
76
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
3.0
118.5
651
2321
SAA02
NOMESCO Finland
Basic examination of mouth
3.5
102.8
2974
22178
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.5
102.2
403
1172
K07.60
ICD-10 Finland
Snapping jaw
3.6
101.7
370
1020
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
27.8
98.5
71
24
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
3.2
92.9
430
1377
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
3.0
91.6
479
1645
WZA90
NOMESCO Finland
Other medical or dental certificate
2.2
91.6
1211
6398
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.1
90.5
423
1362
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
17.7
79.2
68
36
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
4.1
78.7
233
553
EB1TW
NOMESCO Finland
3D modelling of dentition
20.9
72.5
58
26
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
39.9
72.0
47
11
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
6.3
71.1
126
191
SAA01
NOMESCO Finland
Simple examination of mouth
2.4
71.0
2791
21198
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
11.5
70.8
77
63
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
2.7
70.5
448
1694
K00.00
ICD-10 Finland
Hypodontia
4.1
68.7
199
464
EBB10
NOMESCO Finland
Insertion of dental implant
8.0
68.7
97
114
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.7
68.5
417
1541
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
24.9
64.1
48
18
EB1WA, ,
NOMESCO Finland
11.1
63.9
71
60
K02.0
ICD-10 Finland
Caries limited to enamel
1.9
63.4
1289
7696
K03.64
ICD-10 Finland
Dental calculus supragingival
1.9
63.4
1587
10122
SDA03
NOMESCO Finland
Periodontal treatment
1.9
62.7
1451
9021
Z01.2
ICD-10 Finland
Dental examination
1.9
61.7
2110
14782
K03.66
ICD-10 Finland
Tooth plaque
2.3
58.8
533
2361
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
12.8
58.1
59
43
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.8
55.5
1425
9041
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
4.0
54.3
164
394
K07.13
ICD-10 Finland
Retrognaty, mandibular
3.5
53.7
193
523
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
10.9
49.9
56
48
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
15.0
48.3
45
28
EBB15
NOMESCO Finland
Insertion of dental implant abutment
9.4
48.1
60
60
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
7.2
47.4
73
95
SFA10
NOMESCO Finland
One-surface restoration
1.7
47.2
2118
15452
EBA00
NOMESCO Finland
Extraction of tooth
1.7
47.0
1570
10568
K05.30
ICD-10 Finland
Periodontitis complex
2.3
46.7
411
1788
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
9.9
46.7
56
53
SCA01
NOMESCO Finland
Preventive oral health care, short
1.7
44.9
1895
13508
EB1S1
NOMESCO Finland
Photography of teeth
5.3
44.5
92
162
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
5.5
43.6
87
148
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.7
43.3
1026
6249
D82
ICPC
Teeth/gum disease
1.7
42.6
1539
10483
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
3.3
42.5
165
470
OIKK, ,
NOMESCO Finland
2.1
42.4
472
2250
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
4.3
41.9
113
249
EEC02
NOMESCO Finland
Rapid expansion of maxilla
205.1
41.6
44
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
41.6
321
1317
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.8
40.2
698
3865
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
3.9
39.8
123
300
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.9
39.6
566
2944
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
39.5
1591
11061
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
4.0
39.2
114
266
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.8
39.1
799
4641
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
39.1
2563
20158
SJE90
NOMESCO Finland
Orthodontic finishing
5.4
38.9
80
140
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.6
37.4
1759
12635
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
5.9
36.6
68
108
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.0
36.2
441
2165
K07.61
ICD-10 Finland
Cracking jaw joint
3.2
36.1
151
450
K02.1
ICD-10 Finland
Caries of dentine
1.6
33.7
2195
16829
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.0
33.6
402
1959
K07.4
ICD-10 Finland
Malocclusion, unspecified
3.4
32.8
122
338
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
2.6
32.7
205
762
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.6
32.6
2102
16012
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
32.1
1032
6700
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
10.4
32.1
37
33
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
31.7
824
5069
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
3.9
31.5
94
224
SPC20
NOMESCO Finland
Implant borne crown
7.6
30.8
45
55
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.7
30.7
749
4529
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.8
30.7
583
3290
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
11.4
30.2
33
27
D19
ICPC
Teeth/gum symptom/complaint
1.5
29.6
1227
8408
K03.00
ICD-10 Finland
Approximal wear
2.1
29.2
320
1506
OIKH, ,
NOMESCO Finland
2.0
28.9
329
1570
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
7.5
28.5
42
52
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.5
28.4
1372
9697
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
27.7
1069
7187
SAE02, ,
NOMESCO Finland
3.7
27.4
88
221
OIKVA, ,
NOMESCO Finland
2.3
27.0
219
915
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.5
26.4
174
662
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
4.1
26.3
74
169
SCA02
NOMESCO Finland
Preventive oral health care
1.6
25.7
852
5519
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.8
24.9
79
197
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
7.0
24.8
39
52
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.6
24.8
752
4766
EB4VA, ,
NOMESCO Finland
1.6
24.0
622
3789
SPB20
NOMESCO Finland
Temporary bridge
9.3
24.0
30
30
K06.00
ICD-10 Finland
Local gingivore traction
3.3
23.7
92
262
SXC03
NOMESCO Finland
Other oral or dental procedure
5.4
23.7
48
83
H02AB09
ATC
hydrocortisone; systemic
2.6
23.2
137
494
K01.12
ICD-10 Finland
Retained canine with obstruction in the upper jaw
4.5
23.2
57
117
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.4
22.9
163
642
127
Kela drug reimbursment
Transplant complication
3.5
22.9
80
213
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
22.9
346
1813
K07.28
ICD-10 Finland
Another anomaly in the relationship between the dental arches
10.0
22.8
27
25
G47.3
ICD-10 Finland
Sleep apnoea
1.7
22.3
520
3082
SFA20
NOMESCO Finland
Two-surface restoration
1.4
21.4
1863
14456
OIKAL, ,
NOMESCO Finland
2.2
21.3
184
788
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.6
21.2
650
4111
602
Kela drug reimbursment
Children's severe malnutrition
3.2
21.1
85
248
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
8.1
21.0
29
33
OIKRE, ,
NOMESCO Finland
3.1
20.9
87
259
OIKJA, ,
NOMESCO Finland
3.3
20.7
81
232
Q35.1
ICD-10 Finland
Cleft hard palate
8.9
20.2
26
27
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
3.0
20.0
91
286
-1, ,
NOMESCO Finland
1.4
19.7
1501
11305
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
3.4
19.7
71
193
K05.31
ICD-10 Finland
Periodontitis pronounced
2.0
19.6
235
1140
ZXA10
NOMESCO Finland
Bilateral
1.6
19.5
469
2794
EB1VA, ,
NOMESCO Finland
1.6
19.3
531
3269
Z3231
NOMESCO Finland
Registered nurse
1.5
19.1
870
5964
OAA40, ,
SPAT
1.7
19.0
354
1969
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
18.8
611
3902
OIKIN, ,
NOMESCO Finland
3.6
18.8
64
168
K07.23
ICD-10 Finland
Deep bite
1.8
18.7
327
1786
SPC10
NOMESCO Finland
Standard dental crown
4.0
18.7
53
122
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
18.6
310
1670
K06.18
ICD-10 Finland
Another gingival hyperplasia
5.0
18.0
39
72
SPAT1385
SPAT
Extensive health check-up on fifth grade
1.7
17.7
314
1723
SPB06
NOMESCO Finland
Production of temporary clinic-made tooth- or implant-retained crown or bridge unit
5.1
17.2
37
68
Z13.88
ICD-10 Finland
Special screening examination for other specified diseases and disorders
1.8
17.1
261
1369
K07.33
ICD-10 Finland
Crowding of tooth or teeth
4.4
17.1
44
94
SAALT, ,
NOMESCO Finland
2.3
16.9
130
531
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.4
16.8
120
474
EMAK, ,
NOMESCO Finland
2.4
16.8
120
474
SFA00
NOMESCO Finland
Small restoration
1.6
16.7
431
2605
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
16.6
531
3372
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
15.6
16.5
27
16
L04AD02
ATC
tacrolimus; systemic
3.3
16.4
61
170
FM2CE, ,
NOMESCO Finland
2.3
16.3
124
504
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
3.8
15.9
49
120
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
3.2
15.8
64
188
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.6
15.8
90
320
SPF40
NOMESCO Finland
Removal and reattachment of crown or small bridge
4.5
15.7
39
81
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
5.3
15.7
32
56
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.3
15.6
126
526
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
4.1
15.2
42
95
SFA30
NOMESCO Finland
Three-surface restoration
1.4
15.1
1039
7598
SPA02
NOMESCO Finland
Preparation for dental prosthetics
2.7
15.1
84
295
ECA00
NOMESCO Finland
Surgical exposure of tooth
3.2
15.0
60
175
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.4
14.8
692
4730
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.2
14.8
125
531
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.1
14.8
145
654
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.3
14.7
115
474
K01.0
ICD-10 Finland
Embedded teeth
2.2
14.6
123
522
SGB10
NOMESCO Finland
Root filling of tooth with one root canal
1.7
14.5
296
1685
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
14.3
443
2787
K07.32
ICD-10 Finland
Displacement of tooth or teeth
4.4
14.2
36
76
Z2445
NOMESCO Finland
Psychologist
1.7
13.8
256
1422
K03.11
ICD-10 Finland
Abrasion dentifrice of teeth
2.5
13.7
85
315
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
6.5
13.7
23
33
H01
ICPC
Ear pain/earache
1.4
13.7
598
4032
Z75.1
ICD-10 Finland
Person awaiting admission to adequate facility elsewhere
2.5
13.7
83
305
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
13.6
453
2895
WX882
NOMESCO Finland
High dependency care
2.0
13.4
157
755
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
1.8
13.2
194
1005
UDC00
NOMESCO Finland
Ear microscopy
1.7
13.2
244
1353
SJF02, ,
NOMESCO Finland
3.6
13.2
43
110
SPAT1384
SPAT
Extensive health check-up on first grade
1.7
13.1
247
1377
R06.5
ICD-10 Finland
Mouth breathing
1.7
13.1
266
1513
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
10.5
13.0
25
22
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
3.4
13.0
47
129
Z94.0
ICD-10 Finland
Kidney transplant status
3.3
12.9
50
143
SPE02
NOMESCO Finland
Metal-framed partial denture
3.7
12.9
41
103
K10.00
ICD-10 Finland
Torus mandibularis
4.6
12.8
31
63
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
1.6
12.7
279
1619
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
12.7
279
1620
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
3.2
12.6
49
141
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
5.4
12.5
25
43
OAA50, ,
SPAT
1.9
12.5
159
788
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
12.4
2030
16673
Z2446
NOMESCO Finland
Social worker
1.6
12.4
310
1856
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.9
12.4
158
783
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
12.3
588
4021
R5140
NOMESCO Finland
Monitoring the use of the aid
1.7
12.3
220
1208
H01AC01
ATC
somatropin; parenteral
2.7
12.1
66
230
OIKKK, ,
NOMESCO Finland
3.4
12.1
43
117
EEC00
NOMESCO Finland
Segmental osteotomy of maxilla
120.1
12.0
13
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.4
12.0
576
3944
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
3.8
12.0
36
87
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
11.9
1029
7729
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
11.9
212
1163
ZXX07
NOMESCO Finland
Extent of procedure, 7 units
22.4
11.9
17
7
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
4.5
11.8
29
60
KMAK, ,
NOMESCO Finland
1.3
11.7
1154
8829
WX290
NOMESCO Finland
Other blockage of nerve
1.3
11.6
1700
13700
WX402
NOMESCO Finland
General anaesthesia
1.4
11.5
656
4619
ECB17
NOMESCO Finland
Operation of gingival cleft
19.6
11.5
17
8
SJC20
NOMESCO Finland
Extraoral traction appliance arrangement incl. patient instructions
2.4
11.4
79
310
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
2.4
11.2
79
312
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
10.8
11.2
21
18
XF602
NOMESCO Finland
Bloodpressure monitoring
3.0
11.2
48
147
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.8
11.1
156
798
L17
ICPC
Foot/toe symptom/complaint
1.3
11.1
959
7189
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.8
11.1
155
792
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.5
11.1
312
1920
K02.3
ICD-10 Finland
Arrested dental caries
2.2
11.1
92
390
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
11.0
585
4071
VALMI, ,
NOMESCO Finland
1.3
10.9
1135
8722
Z3226
NOMESCO Finland
Physiotherapist
1.4
10.9
512
3485
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.0
10.9
125
598
Z94.4
ICD-10 Finland
Liver transplant status
4.7
10.8
25
49
K03.18
ICD-10 Finland
Other abrasion of the teeth
2.7
10.7
59
207
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
10.7
806
5920
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
18.5
10.6
16
8
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
1.4
10.6
656
4675
SJB30
NOMESCO Finland
Extraoral traction arrangements and operation instruction, removable appliance
2.0
10.6
117
553
SPC01
NOMESCO Finland
Fixed dental crown
3.1
10.6
45
137
K03.09
ICD-10 Finland
Abrasion of the teeth UNS
3.2
10.6
41
118
A98
ICPC
Health maint/preventive medicine
3.4
10.5
3254
29350
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
10.5
1042
7951
K06.01
ICD-10 Finland
General gingival retraction
4.2
10.5
28
62
J34.2
ICD-10 Finland
Deviated nasal septum
1.9
10.5
130
640
B07.9
ICD-10 Finland
Verruca simplex
1.8
10.4
149
768
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
2.8
10.4
53
179
EBA10
NOMESCO Finland
Operative extraction of tooth
1.4
10.4
600
4230
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
1.7
10.4
189
1045
SPAT1312
SPAT
General health counselling
1.3
10.3
1188
9236
SPAT1301
SPAT
No procedures
1.3
10.3
886
6626
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
3.9
10.3
30
71
SCA03
NOMESCO Finland
Preventive oral health care, extensive
1.6
10.3
250
1487
V03AG01
ATC
sodium cellulose phosphate; systemic
4.0
10.3
29
67
BE00A, ,
NOMESCO Finland
11.0
10.3
19
16
L04AX01
ATC
azathioprine; systemic
1.9
10.2
129
638
SBA00
NOMESCO Finland
Microbiological examinations
2.2
10.1
82
344
EEC99
NOMESCO Finland
Other reconstructive operations on maxilla
101.6
10.1
11
*
F45.8
ICD-10 Finland
Other somatoform disorders
1.6
10.0
232
1365
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.4
9.9
617
4397
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
2.5
9.9
61
227
ZX199
NOMESCO Finland
Other rote
4.0
9.9
28
65
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.6
9.9
259
1569
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.6
9.8
232
1373
OIKSI, ,
NOMESCO Finland
4.6
9.7
23
46
K00.09
ICD-10 Finland
Lack of teeth due to lack of dental development UNS
3.4
9.7
35
96
Z29.8
ICD-10 Finland
Other specified prophylactic measures
1.8
9.7
147
770
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
9.7
299
1875
H66.9
ICD-10 Finland
Otitis media, unspecified
1.4
9.7
473
3238
A11CC03
ATC
alfacalcidol; systemic
2.5
9.7
61
229
WKPAL, ,
NOMESCO Finland
2.0
9.6
97
444
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
9.6
495
3422
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
9.6
1779
14611
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.1
9.5
91
408
T84.60
ICD-10 Finland
Gingivitis associated with dental implants
5.1
9.5
20
36
RETH, ,
NOMESCO Finland
5.1
9.5
20
36
SDA05
NOMESCO Finland
Very demanding periodontal treatment
1.6
9.5
243
1464
SCE00
NOMESCO Finland
Fissure sealant
1.4
9.4
370
2435
WYA10
NOMESCO Finland
Emergency care or similar visit
1.6
9.4
245
1480
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
9.4
232
1385
SPA30
NOMESCO Finland
Grinding of a single crown and bridge pillar or a single post and crown
3.0
9.4
40
122
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
9.4
644
4656
K07.08
ICD-10 Finland
Other specified anomaly in the size of the cores
50.8
9.3
11
*
G50.1
ICD-10 Finland
Atypical facial pain
2.8
9.3
45
148
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
3.6
9.2
30
77
K03.29
ICD-10 Finland
Erosion of teeth occupational
2.4
9.2
59
224
SFB40
NOMESCO Finland
Filling of four surfaces reproduced outside mouth
4.7
9.2
21
41
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
2.9
9.1
41
129
R51.80
ICD-10 Finland
Headache
1.4
9.1
551
3904
K05.1
ICD-10 Finland
Chronic gingivitis
1.6
9.1
220
1308
OAA32, ,
SPAT
1.8
9.1
139
732
XA800
NOMESCO Finland
Neuropsychological investigation
1.7
9.0
171
958
J31.0
ICD-10 Finland
Chronic rhinitis
1.5
8.9
242
1476
L04AA01
ATC
[U] ciclosporin
3.2
8.9
35
102
SPAT1310
SPAT
Counselling related to known health issue
1.3
8.9
983
7572
K02.2
ICD-10 Finland
Caries of cementum
2.1
8.8
82
365
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
8.8
509
3584
K01.14
ICD-10 Finland
Retained premolar with obstruction in the upper jaw
7.4
8.7
20
25
Z94.1
ICD-10 Finland
Heart transplant status
4.7
8.7
20
39
OIKQH, ,
NOMESCO Finland
12.6
8.7
15
11
RK220, ,
NOMESCO Finland
3.8
8.7
26
63
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
3.4
8.7
31
85
SPAT1058
SPAT
PEF monitoring instruction
1.6
8.6
195
1140
SPAT1263
SPAT
Sampling
1.3
8.6
1220
9672
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
8.6
1086
8496
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.7
8.5
152
836
K05.18
ICD-10 Finland
Chronic gingivitis
1.5
8.5
264
1658
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.5
8.5
287
1834
K59.09
ICD-10 Finland
Constipation, unspecified
1.7
8.5
161
900
Z2221
NOMESCO Finland
Medical doctor
1.3
8.5
678
4999
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
9.2
8.5
17
17
SXC05, ,
SPAT
9.2
8.5
17
17
SGC00
NOMESCO Finland
Medication, disinfection of root canals
1.5
8.5
276
1752
Q37.99
ICD-10 Finland
Cleft palate with cleft lip NOS
46.1
8.4
10
*
7490A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS COMPLETA]
46.1
8.4
10
*
Z00.1
ICD-10 Finland
Routine child health examination
1.3
8.3
797
6020
101
Kela drug reimbursment
Anterior pituitary hypofunction
2.6
8.3
47
168
M79.1
ICD-10 Finland
Myalgia
1.4
8.3
411
2820
XX7LW, ,
NOMESCO Finland
12.9
8.3
14
10
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.4
8.2
429
2966
R4190
NOMESCO Finland
Nutritional therapy
1.6
8.2
217
1317
RK120, ,
NOMESCO Finland
4.9
8.1
18
34
EC1VA, ,
NOMESCO Finland
1.7
8.1
153
854
SPA05
NOMESCO Finland
Surgical guide
15.0
8.1
13
8
4361
FHL
Lip plastic or reconstruction due to cleft lip
25.4
8.1
11
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.7
8.1
158
891
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
3.2
8.1
31
89
UDM02
NOMESCO Finland
Sinoscopy
2.4
8.0
52
199
RK230, ,
NOMESCO Finland
4.2
8.0
21
46
SPAT1153
SPAT
Removal of sutures
1.3
8.0
594
4334
E0000UV, ,
ATC
1.2
7.9
1299
10436
Z31.5
ICD-10 Finland
Genetic counselling
1.6
7.9
193
1151
DFF20
NOMESCO Finland
Audiometry for children
2.7
7.9
42
146
R4110
NOMESCO Finland
Physiotherapy
1.3
7.8
668
4964
SPAT1260
SPAT
Consultation of another employee
1.4
7.8
442
3095
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
2.7
7.8
40
136
RD210, ,
NOMESCO Finland
1.8
7.8
110
566
K07.68
ICD-10 Finland
Other disorders of the jaw joint
3.0
7.8
34
106
QA9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head or neck, unspecified
6.5
7.7
19
27
K03.28
ICD-10 Finland
Other erosion of teeth
1.9
7.7
89
430
R01AD12
ATC
fluticasone furoate; nasal
1.3
7.6
999
7826
EAB30
NOMESCO Finland
Correction of cleft lip
9.2
7.6
15
15
XX4AW, ,
NOMESCO Finland
2.6
7.5
44
160
OAA31, ,
SPAT
1.7
7.5
128
696
K08.80
ICD-10 Finland
Toothache NOS
1.5
7.5
275
1787
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
6.7
7.4
18
25
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.9
7.4
98
494
4364
FHL
Pharyngeal tongue plastic
41.5
7.4
9
*
ECA55
NOMESCO Finland
Complicated periodontal flap surgery
4.5
7.4
18
37
KAC00
NOMESCO Finland
Nephrectomy
4.0
7.4
21
49
5AB14, ,
NOMESCO Finland
4.1
7.4
20
45
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
8.7
7.3
15
16
RK110, ,
NOMESCO Finland
3.3
7.3
27
76
ECA50
NOMESCO Finland
Periodontal flap surgery
3.5
7.3
25
67
WX400
NOMESCO Finland
Inhalation anesthesy
1.6
7.3
153
881
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
23.1
7.3
10
*
EEC45
NOMESCO Finland
Reconstruction of maxilla using bone graft
23.1
7.3
10
*
R06.0
ICD-10 Finland
Dyspnoea
1.3
7.2
558
4088
K05.19
ICD-10 Finland
Gingivitis (chronic) ulcerative
1.8
7.2
104
540
Q37.90
ICD-10 Finland
Unspecified cheft palate with cleft lip, unilateral
73.9
7.2
8
*
N03AX16
ATC
[U] pregabalin
1.4
7.1
400
2798
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.6
7.1
142
808
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
2.6
7.1
41
149
H13
ICPC
Plugged feeling ear
1.4
7.0
400
2803
E34.35
ICD-10 Finland
Abnormal growth retardation
2.2
7.0
59
253
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.5
7.0
243
1562
DFF00
NOMESCO Finland
Pure tone audiometry
1.5
7.0
192
1177
L04AD01
ATC
ciclosporin; systemic
2.1
7.0
60
260
ZX121
NOMESCO Finland
Central venous catheter
3.1
6.9
29
88
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.1
6.9
65
292
SPAT1315
SPAT
Periodic health check-up of children and adolescents
1.2
6.8
1326
10793
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.6
6.8
170
1019
DJD20
NOMESCO Finland
Plastic repair of septum of nose
1.9
6.8
77
369
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
2.6
6.8
39
141
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.7
6.8
116
633
RS311, ,
NOMESCO Finland
4.4
6.8
17
36
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
2.6
6.8
38
136
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.6
6.7
164
978
K03.1
ICD-10 Finland
Abrasion of teeth
2.3
6.7
49
198
XQ800
NOMESCO Finland
Prick test
1.4
6.7
279
1857
HAMTE, ,
NOMESCO Finland
3.3
6.7
25
71
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.5
6.6
185
1140
SPA60
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 1 to 3 units
2.9
6.6
30
96
ECA70
NOMESCO Finland
Regenerative periodontal surgery or gingival graft
5.5
6.6
18
30
R74
ICPC
Upper respiratory infection acute
1.2
6.5
1345
10997
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.3
6.5
48
195
WX722
NOMESCO Finland
PEEP
1.8
6.5
89
455
J01CA04
ATC
amoxicillin; systemic
1.3
6.5
2785
24524
K04.1
ICD-10 Finland
Necrosis of pulp
1.4
6.5
270
1798
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.4
6.5
247
1619
Q37.0
ICD-10 Finland
Cleft hard palate with bilateral cleft lip
15.4
6.4
10
6
EBA15
NOMESCO Finland
Extraction of multiple teeth
1.8
6.4
93
484
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
8.6
6.4
13
14
XFE00
NOMESCO Finland
Epicardial ultrasonography
2.5
6.4
38
140
IGY02
NOMESCO Finland
Psychiatric monitoring contact
1.5
6.4
195
1223
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
2.8
6.4
31
103
DHB50
NOMESCO Finland
Turbinoplasty
2.0
6.3
69
327
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
1.7
6.3
122
688
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
1.9
6.3
74
360
SPAT1383
SPAT
Extensive health check-up at 4 years of age
1.5
6.3
186
1159
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
5.2
6.3
18
32
K05.38
ICD-10 Finland
Other chronic periodontitis
2.1
6.2
53
229
R05
ICPC
Cough
1.2
6.2
795
6186
SGA05
NOMESCO Finland
Opening and preparing the root canals, extremely complicated And time consuming
1.5
6.2
160
968
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.3
6.2
441
3194
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
2.6
6.2
35
126
F83
ICD-10 Finland
Mixed specific developmental disorders
1.9
6.2
78
389
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.1
6.2
58
261
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
2.6
6.1
34
121
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
2.0
6.1
66
312
XF400
NOMESCO Finland
ECG with 12 standard connections
1.3
6.1
351
2463
SAE03, ,
NOMESCO Finland
3.0
6.1
26
80
H92.0
ICD-10 Finland
Otalgia
1.4
6.1
241
1590
OIKRM, ,
NOMESCO Finland
+∞
6.1
6
*
SPAT1325
SPAT
Vaccination
1.2
6.0
1041
8349
S29
ICPC
Skin symptom/complaint other
1.3
6.0
575
4323
L20.0
ICD-10 Finland
Besnier prurigo
1.3
6.0
394
2818
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
1.6
6.0
136
798
ECA30
NOMESCO Finland
Excision of lesion of gingiva
2.7
6.0
30
101
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.2
6.0
821
6429
K07.55
ICD-10 Finland
Malocclusion caused by tongue, lip and finger habits
3.4
6.0
21
57
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
3.0
6.0
25
76

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
138
530
2.46
20.54
3.5
3.1
27.64
21.52
mu/l
0.58
131
497
66
182
3.38
17.98
50.0
47.9
6.70
6.98
ug/l
0.59
60
167
35
67
4.85
15.52
7.7
7.2
988177.50
74545.65
u/ml
—
10
23
283
1565
1.73
15.46
2.1
1.9
7.57
7.26
u/l
0.19
206
1165
345
2039
1.62
14.62
11.8
6.8
—
—
—
0
0
414
2565
1.56
14.35
5.8
4.5
1.52
1.60
%
1.02
376
2374
41
96
3.97
14.19
10.0
8.2
1.83
2.66
mg/l
1.93
32
82
58
177
3.05
13.49
44.0
32.6
135.55
136.53
ug/l
0.03
51
159
1460
11389
1.32
13.39
12.1
8.1
1.22
1.22
mmol/l
1.76
1288
10176
547
3646
1.46
13.27
14.1
8.0
1.19
1.16
mmol/l
1.44
514
3451
1235
9508
1.31
12.04
10.1
7.5
—
—
—
0
0
2435
20575
1.35
11.89
4.8
4.2
14.47
14.49
pmol/l
0.17
2215
18868
306
1855
1.57
11.61
4.2
3.8
70.37
68.96
e9/l
0.22
221
1228
230
1303
1.67
11.49
23.1
12.4
1.17
1.16
mg/l
0.12
220
1252
434
2849
1.46
11.29
3.1
2.3
331.04
370.10
nmol/l
4.57
402
2698
395
2551
1.48
11.16
11.3
6.6
7.41
7.41
ph
0.51
331
2127
312
1920
1.55
11.07
2.0
1.8
17.82
17.99
iu/l
0.03
235
1501
469
3138
1.44
11.02
11.3
6.8
1.53
1.43
mmol/l
0.33
427
2623
478
3211
1.43
10.99
11.2
6.8
7.38
7.37
ph
2.00
336
2062
477
3209
1.43
10.87
11.2
6.7
5.85
5.84
kpa
0.12
471
3123
397
2583
1.47
10.79
11.3
6.6
5.05
5.06
kpa
0.11
384
2494
1679
13586
1.28
10.75
9.6
7.3
32.16
31.42
%
1.96
1603
13000
1630
13151
1.28
10.64
9.9
7.5
8.65
8.49
%
1.70
1541
12461
1622
13092
1.28
10.49
9.9
7.5
0.67
0.67
%
0.22
1532
12408
1647
13331
1.27
10.36
9.5
7.2
52.70
53.94
%
3.93
1583
12846
434
2894
1.44
10.36
11.6
6.5
4.96
4.87
kpa
0.48
427
2821
1784
14599
1.27
10.18
10.3
7.7
0.20
0.19
e9/l
0.26
1551
12808
1621
13116
1.27
10.13
9.8
7.4
3.05
2.91
%
1.43
1530
12428
1770
14477
1.27
10.11
9.6
7.3
2.04
2.10
e9/l
1.34
1544
12801
282
1732
1.55
10.09
10.1
5.4
68.14
69.33
ng/l
0.12
261
1614
2709
23460
1.36
9.74
5.6
5.0
1.87
1.85
mu/l
0.39
2548
22257
1730
14158
1.26
9.62
9.7
7.3
0.04
0.04
e9/l
1.41
1477
12184
1727
14152
1.26
9.41
9.7
7.3
0.55
0.55
e9/l
0.62
1474
12181
1292
10235
1.27
9.39
13.6
8.2
1.22
1.22
mmol/l
0.98
1202
9639
1424
11427
1.26
9.22
3.9
2.7
74.40
71.63
nmol/l
3.41
1312
10734
293
1852
1.50
9.17
12.9
7.3
10.00
9.54
kpa
3.53
284
1794
39
121
2.99
8.92
4.1
3.9
—
—
—
0
0
76
338
2.09
8.20
3.1
3.4
219.86
192.02
e6/l
0.54
58
262
1543
12601
1.24
8.20
12.9
10.5
0.00
0.00
e9/l
0.99
1228
10153
498
3531
1.35
8.16
3.4
2.7
2.51
2.48
g/l
0.85
469
3303
85
395
2.01
8.15
3.2
3.2
1444.60
1367.31
e6/l
0.24
68
316
408
2811
1.38
8.01
1.3
1.2
—
—
—
0
0
31
91
3.15
7.81
3.8
3.8
3.33
3.79
%
—
10
37
76
347
2.04
7.67
4.5
3.2
—
—
—
0
0
432
3029
1.36
7.59
1.9
1.7
—
—
—
0
0
398
2764
1.37
7.43
21.4
11.5
24.89
24.74
mmol/l
0.52
398
2755
1849
15485
1.23
7.40
12.0
9.7
3.65
3.84
e9/l
2.80
1574
13363
533
3873
1.32
7.35
3.5
2.7
14.35
14.20
umol/l
0.18
505
3660
31
95
3.02
7.29
2.0
1.8
17.73
18.71
nmol/l
0.10
11
27
61
263
2.16
7.17
3.5
3.6
0.35
0.31
e9/l
0.23
42
163
333
2261
1.40
7.12
2.8
2.3
11.70
11.50
nmol/l
0.14
301
2093
452
3223
1.34
7.09
3.7
2.8
23.01
23.22
%
0.13
431
3049
35
117
2.77
7.08
1.1
1.1
—
—
—
0
0
35
118
2.75
6.97
1.0
1.0
—
—
—
0
0
417
2947
1.35
6.94
2.0
2.0
—
—
—
0
0
720
5490
1.26
6.79
1.6
1.6
20.39
19.56
nmol/l
0.96
606
4836
407
2879
1.34
6.73
18.2
10.1
—
—
—
0
0
1124
9014
1.22
6.68
1.6
1.6
1.97
2.05
u/ml
0.06
237
2211
504
3681
1.31
6.66
12.1
5.7
0.83
0.82
mmol/l
0.49
473
3530
372
2600
1.36
6.66
1.6
1.4
304.97
280.88
u/ml
0.15
353
2426
71
334
1.98
6.65
3.1
3.3
545.30
553.64
e6/l
0.04
53
250
44
176
2.32
6.22
2.0
1.9
—
—
—
0
0
148
883
1.57
6.11
2.5
1.8
—
—
—
0
0
143
848
1.58
6.06
2.6
1.8
115.13
123.72
au/ml
0.36
60
256
569
4274
1.27
6.02
5.3
3.5
884.50
835.65
ng/l
0.12
450
3523
192
1216
1.48
6.01
7.9
3.9
21.32
21.36
s
0.04
173
1102
231
1516
1.43
6.01
1.2
1.2
3.48
3.24
u/ml
0.09
154
942
160
976
1.53
5.99
7.3
5.7
535.81
368.98
mg/l
0.31
108
573
65
309
1.95
5.95
4.6
3.2
1.67
1.75
umol/l
0.34
65
291
57
259
2.04
5.91
5.2
3.4
23.67
25.34
umol/l
0.90
57
246
114
645
1.65
5.86
4.5
6.0
0.89
0.90
%
0.09
107
604
124
720
1.61
5.76
4.4
5.6
1.68
1.57
%
0.51
116
678
1950
16638
1.19
5.61
5.2
4.2
—
2.83
—
0
23
177
1119
1.48
5.61
9.6
4.6
2.97
3.23
g/l
1.79
170
1082
183
1166
1.47
5.58
5.1
3.7
156.35
145.49
ng/l
0.11
163
1038
1137
9257
1.20
5.53
7.6
5.7
37.33
37.29
g/l
0.10
1060
8786
121
706
1.60
5.52
1.5
1.5
0.26
0.29
nmol/l
0.48
84
560
1692
14275
1.19
5.48
3.8
3.3
73.58
82.71
ug/l
1.64
1606
13604
2024
17357
1.19
5.38
8.1
7.3
88.10
85.01
u/l
1.62
1907
16552
991
7997
1.20
5.25
1.6
1.6
1.83
1.96
g/l
2.25
579
4855
619
4767
1.24
5.23
3.3
3.0
96.55
104.55
ug/g
0.35
483
3843
203
1337
1.42
5.21
1.1
1.2
1.71
3.30
u/ml
2.78
140
842
204
1346
1.42
5.19
1.1
1.2
1.22
1.45
u/ml
0.19
135
777
207
1374
1.41
5.10
1.1
1.2
6.76
6.83
u/ml
0.02
145
907
592
4551
1.24
5.07
3.9
2.8
575.41
555.44
mosm/kgh2o
1.08
523
4004
319
2278
1.32
4.95
17.8
10.2
6.92
6.85
mmol/l
0.08
310
2219
663
5180
1.22
4.86
3.7
2.2
1.38
1.11
mg/l
0.53
476
3814
2895
25796
1.28
4.79
14.8
12.2
20.82
21.77
mg/l
0.79
2238
19976
829
6628
1.20
4.78
3.4
2.6
2.57
2.60
mg/l
0.16
741
5827
397
2935
1.28
4.75
1.7
1.5
—
—
—
0
0
1297
10800
1.17
4.64
3.9
3.1
6.36
6.24
ph
2.84
678
5927
861
6931
1.19
4.58
2.9
2.7
54.65
58.96
u/l
1.82
776
6464
303
2175
1.31
4.54
4.8
4.0
32.62
32.07
%
0.34
206
1588
1611
13666
1.17
4.51
7.5
5.5
6.17
6.33
mmol/l
2.75
1496
12786
49
236
1.92
4.41
6.3
4.6
1.43
1.75
ug/l
0.58
49
229
251
1762
1.34
4.41
3.3
3.4
4.77
4.78
pmol/l
0.04
227
1622
46
217
1.96
4.39
1.5
1.1
119.02
114.63
pmol/l
0.29
46
217
450
3414
1.25
4.33
1.3
1.2
—
—
—
0
0
36
157
2.12
4.25
2.8
2.0
—
—
—
0
0
20
66
2.80
4.23
1.2
1.2
—
—
—
0
0
1342
11273
1.16
4.16
7.8
6.4
12.83
12.13
umol/l
0.54
1253
10636
17
52
3.02
4.10
1.5
1.4
7.66
7.11
pmol/l
—
8
19
109
675
1.50
3.92
5.6
3.1
11.23
6.64
umol/l
1.05
86
535
1282
10769
1.16
3.90
3.2
2.8
—
—
estimate
—
0
0
328
2434
1.27
3.82
3.2
3.2
9.75
10.21
g/l
1.56
311
2292
1558
13290
1.15
3.80
4.2
3.5
0.00
0.13
estimate
0.51
282
2516
24
94
2.36
3.67
3.1
2.2
—
—
—
0
0
330
2464
1.26
3.66
4.6
3.4
0.22
0.22
g/l
0.06
308
2339
1550
13240
1.15
3.65
4.2
3.5
0.00
3.80
estimate
1.82
286
2615
2753
24536
1.20
3.62
17.4
13.2
139.67
139.66
mmol/l
0.09
2686
23996
56
301
1.72
3.61
4.8
3.5
—
—
—
0
0
485
3781
1.21
3.59
1.6
1.6
104523046.67
26877903.04
pmol/l
0.93
398
3289
241
1736
1.30
3.57
1.3
1.2
—
—
—
0
0
34
156
2.02
3.56
6.7
4.6
94.96
82.60
mg/l
0.47
28
139
1533
13102
1.14
3.54
4.1
3.5
0.00
0.00
estimate
0.42
283
2623
295
3344
0.79
3.52
1.7
1.7
3.46
3.40
ratio
0.38
214
2409
607
4842
1.19
3.50
3.9
2.9
320.71
325.14
umol/l
0.50
554
4423
329
2471
1.25
3.48
1.8
1.6
1142.64
1165.38
nmol/l
0.19
247
1940
1095
9159
1.15
3.44
2.1
1.9
1.28
1.34
mmol/l
1.69
942
8077
2753
24567
1.19
3.39
17.5
13.3
3.92
3.92
mmol/l
0.00
2669
23948
3166
28710
1.42
3.37
22.5
18.4
88.65
89.06
fl
5.01
3127
28437
32
147
2.01
3.36
2.0
2.3
3.94
3.96
mmol/l
0.13
32
147
1000
8322
1.15
3.36
10.7
8.9
1.14
1.14
inr
0.20
845
6904
31
141
2.03
3.34
2.1
2.3
1.20
1.19
mmol/l
0.26
31
141
929
7693
1.16
3.34
3.3
2.7
0.00
0.04
—
8
75
3165
28703
1.41
3.33
22.6
18.5
262.59
262.24
e9/l
0.11
3070
28023
494
3888
1.20
3.31
1.6
1.4
510.21
509.57
titre
0.00
94
717
86
528
1.51
3.28
4.2
6.4
1.29
1.25
mmol/l
0.16
77
459
3166
28718
1.41
3.28
22.5
18.4
29.66
29.80
pg
4.19
3127
28446
3166
28720
1.41
3.25
22.5
18.5
4.60
4.59
e12/l
0.38
3062
27962
3166
28720
1.41
3.25
23.7
19.0
41.87
40.82
%
0.34
3124
28436
22
88
2.31
3.24
3.5
5.3
6.15
6.07
kpa
0.12
22
83
40
202
1.83
3.21
3.0
2.5
-0.01
0.40
mmol/l
0.42
35
184
3167
28735
1.41
3.20
22.6
18.5
6.71
6.70
e9/l
0.01
3066
27973
750
6132
1.16
3.18
5.5
4.0
7.39
7.39
ph
0.17
545
4245
21
83
2.34
3.18
3.6
5.0
5.22
5.08
kpa
0.28
21
83
884
7317
1.15
3.17
3.1
2.5
—
—
—
0
0
196
2305
0.77
3.17
1.5
1.6
988.84
964.16
mu/l
0.13
172
2033
370
2846
1.22
3.15
7.6
3.9
6.29
6.74
umol/l
0.30
324
2446
230
1679
1.28
3.11
4.6
3.8
7.36
7.34
ph
0.46
148
1233
828
6831
1.15
3.10
3.2
3.0
36.81
50.92
ng/l
0.50
458
3706
31
146
1.96
3.07
2.1
2.3
105.58
105.79
mmol/l
0.08
31
146
876
7262
1.15
3.07
3.2
3.2
2.37
2.37
mmol/l
0.50
789
6745
3166
28736
1.39
3.06
22.9
18.6
135.71
136.06
g/l
0.77
3127
28467
28
128
2.02
3.01
1.1
1.1
471.32
401.23
nmol/l
0.76
22
119
77
473
1.51
2.96
2.1
1.8
—
—
—
0
0
77
473
1.51
2.96
2.1
1.8
—
—
—
0
0
77
474
1.51
2.94
2.1
1.8
—
—
—
0
0
77
474
1.51
2.94
2.1
1.8
—
—
—
0
0
154
1076
1.33
2.89
18.4
12.6
16.17
16.12
%
0.08
148
1040
32
156
1.90
2.88
2.7
1.8
5.09
4.61
nmol/l
0.24
32
151
77
476
1.50
2.88
1.2
1.3
1.10
3.23
u/ml
1.83
50
265
162
1142
1.32
2.86
7.3
5.9
1.16
1.27
%
0.63
162
1135
14
48
2.69
2.82
3.1
2.4
97.21
98.96
g/l
0.35
14
48
1039
8757
1.13
2.80
2.0
1.8
100.41
97.01
pmol/l
1.52
517
4752
309
2364
1.22
2.79
1.9
1.5
—
—
—
0
0
1816
15832
1.12
2.79
4.8
4.1
3158.50
777.02
e6/l
0.58
24
201
746
6154
1.15
2.77
8.5
4.9
89.71
91.07
%
0.94
734
6033
77
482
1.48
2.73
1.6
1.5
16.77
17.40
u/l
0.08
67
418
96
628
1.42
2.71
1.7
1.8
—
12.64
—
0
11
325
2508
1.21
2.70
1.3
1.3
132.38
144.41
u/ml
0.19
112
886
143
1000
1.33
2.69
1.3
1.2
—
—
—
0
0
49
278
1.63
2.67
2.9
2.8
0.90
0.71
e9/l
1.00
49
271
228
2575
0.80
2.67
1.4
1.6
3.41
3.34
mmol/l
0.41
150
1670
125
860
1.35
2.63
1.7
1.3
—
—
—
0
0
52
302
1.59
2.60
1.2
1.2
1.04
25.42
u/ml
1.65
41
221
60
361
1.54
2.58
1.3
1.4
—
—
—
0
0
16
318
0.46
2.57
1.7
1.7
7.80
7.44
mmol/l
0.35
16
308
160
1145
1.30
2.57
2.4
1.6
165.07
202.47
u/ml
1.23
81
596
60
362
1.53
2.55
1.3
1.4
6.06
6.51
g/l
0.68
47
290
60
362
1.53
2.55
1.3
1.4
0.44
0.36
g/l
1.07
47
287
60
362
1.53
2.55
1.3
1.4
2.29
2.69
g/l
1.33
48
289
44
247
1.65
2.52
1.3
1.2
—
—
—
0
0
30
151
1.84
2.49
1.3
1.2
—
—
—
0
0
687
5687
1.14
2.41
3.0
2.5
—
—
—
0
0
182
1337
1.27
2.40
2.9
2.9
66.51
66.97
g/l
0.38
167
1268
2604
23287
1.14
2.40
19.0
15.3
13.25
13.26
%
0.26
2567
22937
967
8182
1.12
2.39
8.8
6.6
—
—
—
0
0
100
676
1.37
2.38
1.4
1.4
315.89
318.84
ug/g
0.05
61
354
127
891
1.32
2.37
2.6
2.3
—
—
—
0
0
976
8267
1.12
2.37
2.0
1.9
—
—
—
0
0
39
216
1.67
2.37
3.0
2.2
—
—
—
0
0
790
6611
1.13
2.34
3.1
2.6
—
—
—
0
0
78
507
1.43
2.33
1.7
1.6
349.66
362.48
mu/l
0.18
62
424
54
326
1.53
2.32
5.2
8.6
10.60
11.51
mmol/l
1.83
48
292
250
1913
1.22
2.29
1.8
2.0
1.08
1.22
g/l
1.73
238
1801
20
90
2.05
2.29
1.2
1.2
43.27
34.74
u/ml
—
8
15
54
327
1.53
2.29
5.2
8.6
105.40
105.40
mmol/l
0.00
48
293
109
753
1.34
2.27
1.3
1.3
5.58
14.32
u/ml
1.09
11
104
50
300
1.54
2.22
1.7
1.3
9.89
6.96
u/ml
0.30
33
196
868
7338
1.12
2.15
3.4
2.8
0.07
0.03
estimate
0.44
230
2109
254
1962
1.21
2.14
14.6
10.2
0.79
0.52
mmol/l
0.62
211
1621
988
8417
1.11
2.14
4.6
3.6
29.98
31.12
u/l
0.64
951
8027
386
3095
1.17
2.12
2.7
2.9
3.81
4.75
e9/l
3.09
329
2758
62
394
1.46
2.11
1.3
1.3
—
—
—
0
0
257
1990
1.20
2.11
14.5
10.2
7.42
7.41
ph
0.58
129
985
26
133
1.81
2.09
1.0
1.1
27.67
15.53
u/ml
—
6
25
101
700
1.34
2.09
1.7
1.4
4.75
4.90
ug/l
0.04
92
652
5
9
5.12
2.07
3.2
8.0
—
—
—
0
0
67
434
1.43
2.07
1.1
1.2
—
—
—
0
0
8
23
3.21
2.07
2.4
1.9
—
—
—
0
0
68
442
1.42
2.07
1.1
1.1
3.36
7.17
iu/ml
2.08
12
92
218
1666
1.22
2.05
14.5
10.8
123.12
122.37
g/l
0.20
210
1635
816
6895
1.12
2.03
4.0
3.5
0.00
0.00
estimate
0.06
267
2492
107
754
1.32
1.99
1.4
1.3
7.96
8.99
u/ml
—
7
68
255
1986
1.20
1.98
14.7
10.1
5.14
5.14
kpa
0.02
244
1920
255
1986
1.20
1.98
14.7
10.1
14.08
13.44
kpa
0.98
244
1922
20
96
1.92
1.96
2.8
1.8
—
—
—
0
0
260
2034
1.19
1.93
4.1
4.7
0.50
0.55
%
0.19
73
580
132
961
1.27
1.93
3.9
2.6
1.02
1.02
ratio
0.00
117
854
26
137
1.75
1.92
2.5
2.7
198.69
167.98
e6/l
0.24
26
132
68
449
1.40
1.91
1.4
1.3
4.73
13.51
u/ml
0.74
41
220
97
679
1.32
1.90
1.3
1.2
—
—
—
0
0
17
78
2.01
1.89
1.3
1.6
1.06
1.24
iu/ml
—
9
46
8
26
2.84
1.82
5.3
3.2
4.51
4.57
mmol/l
—
8
26
53
338
1.45
1.81
3.8
3.4
1.24
1.34
%
0.13
46
314
5
11
4.19
1.81
1.0
1.3
24.88
35.59
mg/l
—
5
11
15
67
2.06
1.79
3.3
2.6
26.30
31.54
umol/l
—
10
51
233
1819
1.19
1.79
1.9
1.7
310.28
329.21
mu/l
0.40
214
1658
230
1794
1.19
1.78
15.7
10.7
96.37
95.79
%
0.52
220
1741
891
7621
1.10
1.75
4.5
3.7
8.17
8.45
mmol/l
0.84
775
6837
34
199
1.58
1.73
3.9
3.3
53.02
54.12
%
0.10
28
180
110
795
1.28
1.73
1.8
1.5
57.27
89.78
titre
1.57
11
89
133
984
1.25
1.73
1.1
1.1
8.83
8.47
u/ml
0.06
76
555
85
593
1.33
1.73
11.4
7.7
64.94
64.96
%
0.00
85
588
19
94
1.86
1.73
4.4
7.7
1.20
1.22
mmol/l
0.56
19
86
15
68
2.03
1.73
1.0
1.0
163.20
164.81
g/l
0.11
15
68
259
2050
1.18
1.71
4.5
5.0
0.04
0.10
%
1.37
71
537
36
215
1.55
1.69
1.0
1.0
—
—
—
0
0
543
4531
1.12
1.68
1.4
1.3
19.70
25.82
iu/ml
1.10
156
1195
209
1628
1.19
1.66
3.2
2.6
0.24
0.35
e6/l
0.52
200
1550
262
2081
1.17
1.66
4.7
5.3
0.00
0.23
%
0.83
66
498
10
37
2.49
1.66
1.4
2.8
258.10
4.29
ug/l
—
10
37
501
4169
1.12
1.63
1.4
1.3
11.07
8.64
u/ml
0.20
198
1620
121
893
1.26
1.63
1.1
1.1
27.04
19.43
au/ml
0.27
18
167
624
5261
1.11
1.61
4.4
4.1
—
—
—
0
0
20
104
1.77
1.58
1.9
2.0
6.13
15.71
u/ml
0.61
15
83
491
4089
1.12
1.58
4.2
3.1
4.00
3.14
e6/l
0.68
244
1937
523
5283
0.89
1.57
1.9
2.0
—
—
—
0
0
210
1649
1.18
1.54
1.8
1.5
—
—
—
0
0
14
65
1.99
1.53
2.4
2.7
0.57
0.62
mmol/l
1.99
14
65
79
559
1.31
1.50
1.5
1.7
0.82
0.80
g/l
0.04
65
462
7
25
2.58
1.49
1.6
1.2
296.86
286.40
umol/24h
—
7
25
5
14
3.29
1.49
1.6
2.0
—
—
—
0
0
125
938
1.24
1.48
6.6
7.6
24.68
24.26
mmol/l
0.72
117
898
18
93
1.79
1.46
2.9
2.2
26.50
29.14
%
0.47
18
93
2260
20240
1.09
1.46
5.5
4.8
36.98
37.40
mmol/mol
1.67
2117
19277
189
1480
1.19
1.45
6.1
4.0
1.23
1.23
mmol/l
0.40
166
1285
265
2134
1.16
1.44
4.5
5.0
0.56
0.87
%
1.68
78
622
2383
21396
1.09
1.44
4.4
3.9
5.58
5.65
mmol/l
2.46
2196
20027
415
3445
1.12
1.42
7.3
3.3
29.98
29.76
s
0.31
407
3374
7
26
2.48
1.42
1.1
1.1
—
—
—
0
0
93
678
1.27
1.42
3.3
3.3
8.11
3.45
index
0.65
55
397
119
893
1.23
1.42
1.1
1.1
0.84
0.54
u/ml
0.23
50
348
105
777
1.25
1.42
1.5
2.2
1.41
1.36
g/l
0.20
87
681
86
621
1.28
1.42
1.2
1.2
—
—
—
0
0
15
74
1.87
1.41
1.4
1.3
—
—
—
0
0
18
95
1.75
1.38
2.9
2.0
95.56
97.61
ng/l
0.03
18
95
19
102
1.72
1.38
3.4
2.1
5.22
2.09
nmol/l
0.44
19
93
296
2413
1.14
1.36
1.4
1.5
—
—
—
0
0
56
383
1.35
1.36
1.1
1.1
0.51
2.28
u/ml
1.26
36
188
32
198
1.49
1.33
2.1
1.6
—
—
—
0
0
238
1917
1.15
1.31
2.3
2.1
6.15
6.19
ph
0.28
145
1225
145
1121
1.20
1.31
1.7
2.0
6.17
7.68
iu/ml
0.29
32
251
52
354
1.36
1.31
1.1
1.1
—
—
—
0
0
2905
26364
1.12
1.31
16.6
13.9
68.03
69.07
umol/l
1.41
2858
26047
128
978
1.21
1.30
1.1
1.1
3.36
7.14
eliau/ml
0.94
16
125
9
40
2.07
1.28
1.0
1.2
—
—
—
0
0
261
2121
1.14
1.27
16.8
10.2
1.40
1.30
mmol/l
0.75
254
2084
21
119
1.63
1.27
1.8
1.8
1.51
1.26
nmol/l
0.40
15
94
12
57
1.94
1.26
1.2
1.7
42.15
41.57
g/l
0.19
12
57
261
2123
1.14
1.26
2.0
2.0
0.00
0.01
estimate
1.05
59
520
159
1246
1.18
1.25
2.2
2.1
11.89
7.52
ug/l
0.60
137
1112
746
6426
1.09
1.24
5.6
4.7
—
—
—
0
0
1073
9379
1.08
1.24
5.7
4.1
47.32
71.89
e6/l
1.06
729
6224
14
71
1.82
1.23
1.1
1.2
—
—
—
0
0
15
78
1.77
1.22
2.0
3.3
69.69
28.82
mg/l
—
9
32
33
210
1.45
1.22
4.9
4.5
0.76
0.76
index
0.00
33
210
43
288
1.38
1.21
1.2
1.2
—
—
—
0
0
8
34
2.17
1.21
1.1
1.0
—
—
—
0
0
507
4300
1.10
1.19
4.2
3.0
0.98
0.97
e6/l
0.02
260
2151
52
363
1.32
1.14
4.2
2.4
68.26
72.60
mmol/l
0.28
46
317
1119
9829
1.07
1.12
3.9
3.2
0.03
0.03
estimate
0.13
231
2142
64
463
1.28
1.09
3.2
3.2
24.73
24.78
mg/l
0.00
45
310
128
999
1.19
1.08
1.5
1.6
6.57
8.51
u/ml
0.52
24
253
18
103
1.61
1.07
1.2
1.4
142.77
106.24
nmol/l
0.26
13
78
40
271
1.36
1.07
1.2
1.2
—
—
—
0
0
134
1052
1.18
1.06
1.1
1.1
5.23
5.50
u/ml
0.07
84
633
13
68
1.76
1.06
1.3
1.7
0.29
0.32
iu/ml
—
8
42
51
360
1.31
1.05
1.3
1.3
—
45.44
—
0
15
106
1159
0.84
1.04
1.4
1.5
59.00
60.93
ug/l
0.16
91
988
79
888
0.81
1.03
1.4
1.6
—
—
—
0
0
78
876
0.81
1.01
1.4
1.5
—
—
—
0
0
184
1488
1.15
1.01
1.3
1.3
194.85
230.01
miu/ml
0.77
83
723
24
150
1.48
1.00
1.1
1.1
399.05
228.91
iu/ml
0.55
24
150
48
339
1.31
1.00
1.9
2.0
291.61
287.94
mosm/kgh2o
0.68
36
265
38
259
1.35
1.00
1.3
1.3
—
—
—
0
0
65
479
1.25
0.98
1.3
1.3
2.37
4.52
u/ml
3.09
30
244
5
21
2.19
0.98
3.0
1.7
—
—
—
0
0
790
6890
1.07
0.96
4.8
3.3
0.21
0.33
e6/l
1.48
582
4907
728
6337
1.07
0.94
3.9
3.2
1.02
1.79
kg/l
1.08
481
3959
57
417
1.26
0.93
1.2
1.2
—
—
—
0
0
38
263
1.33
0.92
1.4
1.2
—
—
—
0
0
30
200
1.38
0.91
1.4
1.7
67.53
52.04
%
1.32
19
134
39
272
1.32
0.90
5.1
4.1
19.42
15.63
index
0.55
33
210
76
843
0.83
0.90
1.4
1.5
1.28
1.27
mm
0.04
55
609
16
94
1.57
0.89
1.8
1.2
—
—
—
0
0
16
94
1.57
0.89
1.8
1.2
—
—
—
0
0
16
94
1.57
0.89
1.8
1.2
—
—
—
0
0
269
2720
0.90
0.89
1.3
1.3
—
—
—
0
0
20
124
1.49
0.88
1.1
1.2
—
—
—
0
0
68
512
1.23
0.87
1.1
1.1
—
—
—
0
0
8
40
1.84
0.86
1.0
1.0
—
—
—
0
0
139
1119
1.15
0.85
2.2
2.1
0.05
0.61
estimate
0.46
40
421
599
5203
1.07
0.83
4.0
2.8
5.92
7.14
e6/l
1.37
551
4690
6
29
1.91
0.83
4.8
3.4
1.75
1.67
mg/l
—
6
22
677
5907
1.07
0.82
2.8
2.3
264.59
234.03
u/l
0.20
639
5678
24
158
1.40
0.80
1.1
1.1
22.60
38.61
iu/ml
1.55
24
158
18
112
1.48
0.80
1.0
1.1
—
4.50
—
0
10
140
1457
0.88
0.78
1.5
1.4
—
—
—
0
0
20
128
1.44
0.78
1.0
1.3
—
78.15
%
—
0
13
29
199
1.34
0.77
1.4
1.3
—
—
—
0
0
115
921
1.15
0.77
2.1
2.4
—
—
—
0
0
886
7815
1.06
0.76
4.9
3.5
37.77
59.91
e6/l
0.79
674
5808
9
49
1.69
0.75
1.0
1.2
—
—
—
0
0
5
22
2.09
0.74
7.8
7.1
156.20
66.42
e6/l
—
5
12
9
50
1.66
0.74
1.1
1.2
—
—
—
0
0
20
130
1.42
0.73
3.0
2.7
82.27
118.25
umol/l
—
6
34
2626
23862
1.06
0.72
19.2
15.3
333.97
333.72
g/l
0.74
2608
23693
6
102
0.54
0.72
1.2
1.3
113.67
68.94
ug/l
—
6
102
9
131
0.63
0.70
1.0
1.1
—
—
—
0
0
24
163
1.36
0.69
1.0
1.1
—
—
—
0
0
5
25
1.84
0.68
1.6
2.3
—
—
—
0
0
5
25
1.84
0.68
1.2
1.0
—
—
—
0
0
24
164
1.35
0.67
5.0
2.5
26.86
71.84
ug/l
0.45
24
144
162
1344
1.11
0.66
1.8
1.7
—
—
—
0
0
30
213
1.30
0.66
12.8
12.7
0.63
0.60
mmol/l
0.47
30
201
486
4232
1.07
0.65
1.7
1.7
—
—
—
0
0
7
41
1.57
0.64
1.3
1.2
99.86
67.73
ug/l
—
7
41
39
443
0.81
0.63
2.1
2.5
—
—
—
0
0
22
150
1.35
0.63
1.2
1.6
23.01
38.72
%
1.38
14
97
14
184
0.70
0.62
1.5
1.2
—
—
—
0
0
26
183
1.31
0.62
1.3
1.3
194.24
221.59
pmol/l
0.21
26
183
2870
26185
1.07
0.61
12.4
10.2
26.33
26.32
u/l
0.01
2770
25546
141
1439
0.90
0.61
1.5
1.6
—
—
—
0
0
15
96
1.44
0.61
3.4
2.4
—
—
—
0
0
10
58
1.59
0.61
1.7
2.0
—
—
—
0
0
126
1037
1.12
0.60
1.3
1.2
0.38
0.82
u/ml
—
9
71
155
1292
1.11
0.60
3.1
2.5
—
—
—
0
0
18
224
0.74
0.59
1.1
1.2
—
—
—
0
0
11
66
1.54
0.59
8.3
5.8
—
—
—
0
0
268
2296
1.08
0.58
1.3
1.3
86.50
175.46
titre
—
10
80
11
149
0.68
0.58
1.5
1.3
73.55
73.07
umol/l
0.03
11
149
134
1112
1.11
0.57
2.9
2.9
25.74
58.43
u/ml
1.95
128
1073
80
643
1.15
0.56
2.5
2.4
0.70
0.73
nmol/l
0.16
62
561
23
162
1.31
0.55
1.7
1.8
5.42
3.28
nmol/l
0.26
17
128
327
2830
1.07
0.55
2.2
1.9
—
—
—
0
0
9
56
1.48
0.54
1.1
1.2
—
—
—
0
0
22
155
1.31
0.53
1.4
2.6
44.03
41.43
%
0.48
13
73
16
107
1.38
0.53
1.3
1.2
—
—
—
0
0
31
352
0.81
0.53
2.1
2.5
88.68
110.69
ug/min
0.15
13
222
757
6721
1.05
0.52
4.7
3.3
0.52
4.83
estimate
—
5
20
17
207
0.75
0.50
1.2
1.2
—
—
—
0
0
36
273
1.22
0.50
1.2
1.3
11.39
18.29
u/ml
0.33
29
201
282
2438
1.07
0.50
2.2
2.0
—
—
—
0
0
37
282
1.21
0.49
1.6
1.5
1.12
1.22
promille
0.15
31
225
16
109
1.35
0.48
2.0
1.3
79.81
79.82
nmol/24h
0.00
16
109
144
1213
1.10
0.48
22.4
12.8
0.69
0.66
%
0.46
144
1208
81
661
1.13
0.48
8.1
3.8
7.40
7.41
ph
0.14
81
656
51
403
1.17
0.47
1.1
1.1
1.50
1.45
g/l
0.42
45
375
18
126
1.32
0.47
1.1
1.2
0.75
1.15
u/ml
0.16
18
126
27
201
1.24
0.45
1.3
1.6
0.61
0.52
e9/l
1.00
27
201
17
119
1.32
0.44
1.6
2.5
0.50
2.00
u/field
2.43
12
83
187
1847
0.93
0.44
2.1
2.1
—
—
—
0
0
15
103
1.34
0.44
1.1
1.1
—
—
—
0
0
17
202
0.77
0.44
1.4
2.7
3.20
1.73
mmol/l
0.73
11
158
7
47
1.37
0.44
1.3
1.2
—
—
—
0
0
7
47
1.37
0.44
3.0
2.4
—
—
—
0
0
7
47
1.37
0.44
1.0
1.0
8.70
0.21
u/ml
—
7
41
62
502
1.14
0.43
1.6
1.7
—
1876.92
—
0
13
0
14
0.00
0.41
0.0
1.8
—
263.33
—
0
9
0
14
0.00
0.41
0.0
1.2
—
4.88
—
0
8
118
995
1.09
0.41
1.8
1.9
1.24
1.17
g/l
1.65
112
955
36
280
1.19
0.41
1.1
1.1
—
—
—
0
0
140
1393
0.92
0.41
3.5
4.4
4.53
20.23
ug/l
1.60
103
1062
870
8222
0.96
0.41
2.2
2.2
—
—
—
0
0
0
16
0.00
0.40
0.0
5.2
—
7.77
—
0
16
10
127
0.72
0.40
1.2
1.5
37.13
34.39
g/l
—
10
111
146
1245
1.08
0.40
22.2
12.7
94.58
94.18
%
0.30
146
1240
5
32
1.44
0.39
1.6
1.3
—
—
—
0
0
72
593
1.12
0.39
1.1
1.1
5.38
3.74
eliau/ml
0.37
22
216
17
122
1.28
0.39
2.1
1.3
140.00
139.26
nmol/l
0.03
17
122
20
147
1.25
0.38
3.5
2.7
—
—
—
0
0
9
61
1.36
0.38
1.0
1.1
—
—
—
0
0
9
61
1.36
0.38
1.0
1.1
—
—
—
0
0
9
61
1.36
0.38
1.0
1.1
—
—
—
0
0
9
62
1.34
0.38
1.0
1.2
—
—
—
0
0
424
3749
1.05
0.38
5.0
4.5
1.69
1.97
ug/l
0.95
380
3433
8
106
0.69
0.37
1.0
1.1
—
—
—
0
0
5
34
1.35
0.37
5.8
6.9
59.20
40.38
umol/l
—
5
28
9
64
1.29
0.37
2.6
1.6
—
—
—
0
0
1031
9695
0.97
0.36
3.0
2.6
—
—
—
0
0
260
2515
0.95
0.35
2.4
2.4
2352.23
7289.47
u/l
3.78
77
829
50
406
1.14
0.35
1.1
1.1
10.12
16.44
u/ml
0.93
12
126
17
124
1.26
0.35
1.1
1.1
0.45
3.72
u/ml
2.52
12
99
41
329
1.15
0.34
1.2
1.3
—
0.39
nmol/l
—
0
14
24
264
0.84
0.34
1.8
1.7
—
—
—
0
0
15
108
1.28
0.34
3.4
2.3
—
—
—
0
0
1878
17072
1.03
0.34
4.9
3.4
34.72
37.87
u/l
1.49
1771
16350
57
469
1.12
0.33
1.2
1.3
—
—
—
0
0
26
201
1.19
0.33
1.8
2.2
1.21
0.93
%
0.71
18
106
33
261
1.17
0.33
1.2
1.3
—
—
nmol/l
—
0
0
19
142
1.23
0.33
1.4
1.2
—
37.95
—
0
16
33
262
1.16
0.32
2.9
2.2
25.81
29.35
mg/l
0.40
21
163
33
262
1.16
0.32
5.9
4.2
6.15
6.72
mmol/l
0.66
26
228
24
185
1.20
0.32
1.0
1.0
3.35
3.38
kpa
0.04
18
142
73
612
1.10
0.31
2.5
2.1
1.87
2.11
ug/l
0.12
67
549
12
140
0.79
0.29
1.1
1.1
99.20
207.90
ng/l
—
5
30
24
187
1.18
0.29
1.0
1.0
7.04
7.23
kpa
0.22
18
144
24
187
1.18
0.29
1.0
1.0
—
—
—
0
0
8
100
0.74
0.29
3.0
3.1
—
—
—
0
0
11
78
1.30
0.28
1.0
1.1
—
—
—
0
0
419
3735
1.04
0.28
4.5
3.4
891.15
548.89
ng/l
0.37
256
2275
171
1494
1.06
0.27
1.3
1.2
—
—
—
0
0
85
725
1.08
0.27
2.9
2.7
320.85
359.11
ug/l
0.18
78
670
45
459
0.90
0.26
1.1
1.1
—
—
—
0
0
27
216
1.15
0.25
11.4
5.4
11.43
9.55
mg/l
0.82
27
181
12
88
1.26
0.25
1.1
1.2
—
—
—
0
0
198
1743
1.05
0.24
1.2
1.3
37.94
45.29
au/ml
0.22
12
100
16
176
0.84
0.24
1.1
1.2
—
—
—
0
0
30
243
1.14
0.24
1.2
1.4
10.10
10.75
umol/l
0.26
30
232
30
243
1.14
0.24
1.0
1.0
9.55
8.88
mu/l
0.23
23
193
9
71
1.17
0.24
1.2
1.3
80.22
95.54
umol/l
—
9
65
143
1249
1.06
0.24
22.4
12.5
1.23
1.26
%
0.15
143
1243
58
581
0.92
0.24
1.2
1.2
32.77
998.50
iu/ml
0.62
13
151
28
292
0.88
0.23
1.7
1.6
—
—
—
0
0
5
35
1.31
0.23
6.2
3.9
0.14
0.18
%
—
5
35
261
2318
1.04
0.22
2.7
2.4
32.43
58.14
u/l
0.66
221
1958
18
194
0.85
0.22
2.7
2.6
1.26
1.43
g/24h
—
9
128
88
759
1.07
0.22
3.3
3.2
54.40
55.47
%
0.31
88
759
7
87
0.74
0.22
1.1
1.7
0.00
0.03
estimate
—
7
87
341
3046
1.03
0.22
2.2
1.9
—
—
—
0
0
2401
21961
1.02
0.22
4.9
4.2
4.55
4.62
mmol/l
2.85
2257
20966
149
1308
1.05
0.22
1.0
1.1
—
—
—
0
0
41
342
1.10
0.22
1.4
1.4
6.36
6.97
mmol/l
0.82
35
309
133
1164
1.05
0.21
1.2
1.1
—
—
—
0
0
34
348
0.90
0.21
1.2
1.5
—
7.93
—
0
9
660
6192
0.98
0.21
1.8
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
1.58
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
12
134
0.82
0.21
1.0
1.1
44.67
4.50
u/ml
—
6
61
8
95
0.77
0.21
2.5
2.5
7.70
7.97
mmol/l
—
8
95
23
185
1.14
0.21
5.3
2.6
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
48
405
1.09
0.21
2.0
2.0
—
—
—
0
0
15
116
1.19
0.20
1.3
1.3
—
—
—
0
0
15
116
1.19
0.20
1.2
1.5
33728.57
21197.23
e6/l
—
7
60
0
13
0.00
0.20
0.0
1.6
—
—
—
0
0
0
13
0.00
0.20
0.0
1.0
—
—
—
0
0
55
468
1.08
0.20
1.6
1.6
8891.31
12307.29
e6/l
0.54
35
335
40
335
1.10
0.20
1.2
1.5
284.61
391.66
pmol/l
1.61
31
292
10
74
1.24
0.19
1.2
1.3
—
—
—
0
0
49
416
1.09
0.19
3.0
3.8
27.97
36.81
mg/l
0.86
42
363
140
1345
0.96
0.19
1.5
1.4
—
—
—
0
0
49
417
1.08
0.18
3.0
3.8
33.77
66.47
mg/l
1.19
42
362
85
739
1.06
0.18
1.2
1.2
—
—
—
0
0
573
5370
0.98
0.18
4.5
4.3
9.63
12.34
mg/mmol
0.30
349
3547
28
286
0.90
0.18
2.2
2.1
—
—
—
0
0
7
54
1.19
0.18
1.7
1.6
—
—
—
0
0
18
144
1.15
0.18
2.1
3.1
0.84
0.85
nmol/l
0.05
11
119
7
56
1.15
0.17
1.3
2.3
—
—
—
0
0
32
323
0.91
0.17
1.8
1.8
—
—
—
0
0
11
84
1.21
0.17
1.4
1.9
—
—
—
0
0
52
446
1.07
0.17
9.9
4.2
9.32
9.17
kpa
0.23
52
441
15
159
0.87
0.16
1.3
1.3
—
—
—
0
0
340
3058
1.03
0.16
2.2
1.9
—
—
—
0
0
94
906
0.95
0.15
1.4
1.2
—
—
—
0
0
9
74
1.12
0.15
6.1
6.9
24.74
24.62
mmol/l
—
9
68
9
75
1.10
0.15
1.0
1.1
—
—
—
0
0
2386
22049
0.98
0.14
5.2
4.5
2.73
2.75
mmol/l
0.47
2235
20942
280
2638
0.97
0.14
1.6
1.5
—
—
—
0
0
84
809
0.95
0.14
1.3
1.2
—
—
—
0
0
8
90
0.82
0.13
1.0
1.1
—
—
—
0
0
13
137
0.87
0.13
1.6
2.4
14.46
17.28
umol/l
0.48
13
137
210
1883
1.03
0.13
2.4
2.3
17.03
18.49
au/ml
0.13
28
217
33
281
1.08
0.13
3.6
4.0
30.80
123.40
u/ml
1.78
11
85
84
807
0.96
0.13
1.3
1.2
—
—
—
0
0
10
78
1.18
0.12
1.2
1.4
—
8.94
%
—
0
18
10
78
1.18
0.12
1.0
1.2
—
12.33
%
—
0
6
68
597
1.05
0.12
2.9
3.6
16.85
2531.43
u/ml
0.89
60
520
277
2498
1.02
0.12
1.9
1.8
—
—
—
0
0
51
445
1.06
0.11
10.8
4.2
1.86
2.08
mmol/l
0.35
34
263
335
3030
1.02
0.11
2.2
1.9
—
—
—
0
0
14
114
1.13
0.11
1.2
1.5
—
—
—
0
0
13
135
0.89
0.11
1.0
1.1
0.01
2.15
u/ml
—
6
61
19
192
0.91
0.11
1.1
1.0
18.72
18.40
u/ml
—
9
126
51
446
1.05
0.10
10.8
4.2
4.94
4.95
kpa
0.05
51
441
35
302
1.07
0.10
1.5
1.3
300.00
218.81
titre
—
6
59
35
302
1.07
0.10
1.5
1.3
566.00
186.36
titre
—
5
11
24
239
0.92
0.10
1.1
1.2
0.57
0.65
ratio
0.66
17
138
86
763
1.04
0.10
3.5
2.3
183.28
684.20
e6/l
1.39
68
567
571
5313
0.99
0.10
3.8
3.7
67.28
59.12
mg/l
0.21
356
3571
5
41
1.12
0.10
1.0
1.0
3.00
6.90
u/ml
—
5
41
2362
21801
0.99
0.10
4.9
4.1
1.44
1.45
mmol/l
0.81
2209
20692
88
837
0.97
0.09
3.5
2.1
431.43
455.79
mg/l
0.09
88
807
22
187
1.08
0.09
8.4
4.0
—
107.20
—
0
30
214
2005
0.98
0.08
4.0
3.5
—
—
—
0
0
16
134
1.10
0.08
1.2
1.4
6100.00
3549.01
e6/l
—
8
84
6
65
0.85
0.07
1.0
1.8
—
—
—
0
0
28
243
1.06
0.07
1.0
1.0
—
—
—
0
0
2218
20462
0.99
0.07
4.2
3.6
1.20
1.23
mmol/l
1.79
2056
19374
54
479
1.04
0.07
1.4
2.1
10.72
10.15
g/l
0.48
45
453
10
103
0.89
0.07
1.4
1.7
—
—
—
0
0
10
82
1.12
0.06
1.1
1.3
—
—
—
0
0
84
754
1.03
0.06
3.5
2.2
6.48
17.25
e6/l
1.72
65
535
376
3493
0.99
0.06
2.2
2.6
2.43
2.43
mmol/l
0.07
329
3130
46
408
1.04
0.06
3.3
2.3
—
—
—
0
0
18
177
0.94
0.05
1.5
1.4
273015.80
91831.02
e6/l
—
10
121
237
2155
1.01
0.05
3.0
2.5
—
—
—
0
0
13
110
1.09
0.05
1.9
2.4
617.83
597.62
ml
—
6
74
19
185
0.94
0.04
3.1
4.6
81.64
219.44
umol/l
3.06
11
113
330
3012
1.01
0.04
2.2
1.9
—
—
—
0
0
163
1519
0.99
0.04
1.5
1.6
0.28
0.26
mg/l
0.20
56
661
15
129
1.07
0.04
2.3
2.4
—
—
—
0
0
244
2266
0.99
0.04
3.1
2.8
0.65
0.71
ug/l
0.66
122
1251
12
119
0.93
0.04
1.2
1.5
—
—
—
0
0
92
833
1.02
0.03
7.2
5.0
36.94
36.94
°c
0.07
92
827
79
714
1.02
0.03
3.6
2.3
—
—
—
0
0
10
100
0.92
0.03
5.6
5.2
12.10
7.84
%
—
10
100
10
100
0.92
0.03
2.8
2.6
46.70
43.89
%
—
10
100
286
2650
0.99
0.03
1.2
1.2
—
—
—
0
0
14
137
0.94
0.03
1.1
2.7
56.07
79.39
nmol/l
1.06
14
132
29
276
0.97
0.03
1.8
2.4
2.66
3.65
u/ml
—
10
102
98
914
0.99
0.03
1.3
1.3
—
—
—
0
0
57
514
1.02
0.03
4.4
4.4
1.19
1.40
mmol/l
1.87
57
506
88
798
1.02
0.03
2.2
2.1
3.70
3.84
iu/l
0.07
38
343
25
222
1.04
0.02
7.0
3.8
—
—
—
0
0
25
238
0.97
0.02
1.0
1.1
—
—
—
0
0
57
516
1.02
0.02
7.9
4.0
—
—
—
0
0
104
966
0.99
0.01
2.0
1.7
—
—
—
0
0
31
278
1.03
0.01
1.1
1.3
0.16
0.23
nmol/l
0.53
23
213
929
8534
1.00
0.01
1.6
1.6
—
—
—
0
0
57
532
0.99
0.01
1.1
1.1
—
—
—
0
0
59
536
1.01
0.01
1.1
1.1
—
—
—
0
0
63
573
1.01
0.01
8.7
8.4
—
—
—
0
0
29
273
0.98
0.01
2.0
1.5
—
—
—
0
0
18
160
1.04
0.00
1.1
1.2
13.78
7.76
mm/h
0.79
18
160
11
106
0.95
0.00
1.1
1.3
27.18
28.73
s
0.43
11
106
11
99
1.02
0.00
1.0
1.1
9.23
13.20
u/ml
—
6
54
21
196
0.99
0.00
1.0
1.1
1423.17
1574.24
miu/ml
0.33
21
196
22
206
0.98
0.00
1.2
1.2
—
—
—
0
0
48
444
0.99
0.00
5.3
3.0
—
—
—
0
0
13
124
0.96
0.00
1.6
1.4
132.62
161.10
mmol/24h
1.05
13
124
39
356
1.01
0.00
2.2
2.5
—
—
—
0
0
65
594
1.01
0.00
2.3
2.4
135.36
133.38
g/l
0.28
59
512
40
365
1.01
0.00
2.5
3.6
11.59
2.95
ratio
0.38
24
195
25
235
0.98
0.00
1.3
1.3
1.51
1.82
mmol/l
3.83
25
220
5
49
0.94
0.00
2.6
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
76
0.97
-0.00
2.1
2.8
16.24
16.70
%
—
8
76
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
8.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
0.69
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
37.00
—
0
5
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.06
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
8048.17
—
0
6
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
7
71
0.91
-0.00
1.1
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
919.25
—
0
8

Mortality – FinRegistry

Association

Association between endpoint K11_CROSSBITE and mortality.

Females

Parameter HR [95% CI] p-value
K11_CROSSBITE 0.68 [0.47, 0.99] 0.043
Birth year 0.992 [0.98, 1.0] 0.067

During the follow-up period (1.1.1998 — 31.12.2019), 75 out of 46029 females with K11_CROSSBITE died.

Males

Parameter HR [95% CI] p-value
K11_CROSSBITE 0.639 [0.41, 0.99] 0.046
Birth year 0.988 [0.98, 1.0] 0.012

During the follow-up period (1.1.1998 — 31.12.2019), 110 out of 42490 males with K11_CROSSBITE died.

Mortality risk

Mortality risk for people of age

years, who have K11_CROSSBITE.

N-year risk Females Males
1 0.064% 0.144%
5 0.355% 0.823%
10 0.863% 2.111%
15 1.726% 3.989%
20 2.946% 6.681%

Relationships between endpoints

Index endpoint: K11_CROSSBITE – Crossbite

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data