Myopia

H7_MYOPIA

obsolete_myopia: ['A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.']

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H52.1
  • Hospital discharge: ICD-9 3671
  • Hospital discharge: ICD-8 37002
  • Cause of death: ICD-10 H52.1
  • Cause of death: ICD-9 3671
  • Cause of death: ICD-8 37002

2 out of 7 registries used, show all original rules.

6904

4. Check minimum number of events

None

6904

5. Include endpoints

None

6904

6. Filter based on genotype QC (FinnGen only)

6152

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H52
Name in latin
Myopia

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 48541 28199 20125
Only index persons 43883 25892 17991
Unadjusted period prevalence (%)
Whole population 0.70 0.81 0.56
Only index persons 0.84 0.95 0.69
Median age at first event (years)
Whole population 26.98 31.34 20.76
Only index persons 28.57 32.28 23.23

-FinnGen-

Key figures

All Female Male
Number of individuals 6152 4264 1888
Unadjusted period prevalence (%) 1.31 1.51 0.87
Median age at first event (years) 42.33 41.30 44.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
6460
Matched controls
64600
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
31.2
311.0
203
67
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.2
310.2
941
2543
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.9
307.7
3170
16007
CGD20
NOMESCO Finland
Laser-assisted in situ keratomileusis
1321.2
307.7
489
*
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
289.2
307.7
457
17
H52.1
ICD-10 Finland
Myopia
2943.9
307.7
6256
666
H52.2
ICD-10 Finland
Astigmatism
27.8
307.7
590
233
Z96.1
ICD-10 Finland
Presence of intraocular lens
4.1
275.9
846
2296
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.0
260.9
1422
5550
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.6
250.1
2091
10141
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.7
216.6
1434
6146
H50.52
ICD-10 Finland
Exophoria
24.5
205.9
146
61
H33.0
ICD-10 Finland
Retinal detachment with retinal break
7.0
200.9
315
472
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.6
200.2
730
2214
XCK00
NOMESCO Finland
Perimetry
4.6
197.9
500
1163
H44.2
ICD-10 Finland
Degenerative myopia
58.9
196.6
110
19
H26.4
ICD-10 Finland
After-cataract
4.0
191.5
581
1551
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.3
177.1
485
1199
H52.4
ICD-10 Finland
Presbyopia
5.2
174.6
377
768
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
161.1
154
*
H26.02
ICD-10 Finland
Presenil cataract
5.6
150.0
293
545
H33.3
ICD-10 Finland
Retinal breaks without detachment
4.9
146.2
331
701
H40.0
ICD-10 Finland
Glaucoma suspect
3.3
141.0
573
1848
H25.1
ICD-10 Finland
Senile nuclear cataract
2.4
122.3
998
4612
H35.4
ICD-10 Finland
Peripheral retinal degeneration
10.8
118.8
129
122
H53.0
ICD-10 Finland
Amblyopia ex anopsia
10.0
105.0
120
122
H50.0
ICD-10 Finland
Convergent concomitant strabismus
1024.8
103.5
101
*
S01ED51
ATC
timolol, combinations; ophthalmic
3.3
102.7
402
1262
CKC12
NOMESCO Finland
Photocoagulation of retina
3.7
101.5
335
941
H50.31
ICD-10 Finland
Intermittent exotropia
119.7
98.2
106
9
114
Kela drug reimbursment
Glaucoma
3.2
94.4
399
1311
ZXA10
NOMESCO Finland
Bilateral
2.1
94.2
1075
5646
3671A
ICD-9 Finland
Disorders of refraction and accommodation, Myopia
+∞
91.9
88
*
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
890.8
90.0
88
*
H04.10
ICD-10 Finland
Dry eye syndrome
2.2
87.5
868
4311
WX140
NOMESCO Finland
Parabulbar anesthesy
3.8
82.7
264
724
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.5
82.4
562
2374
H50.2
ICD-10 Finland
Vertical strabismus
41.1
80.9
49
12
XCK10
NOMESCO Finland
Photography of fundus of eye
2.6
80.2
519
2138
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
3.9
80.2
245
652
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.5
79.3
523
2174
H53.2
ICD-10 Finland
Diplopia
4.2
77.6
213
524
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.8
75.7
406
1521
H50.51
ICD-10 Finland
Esophoria
23.7
75.2
54
23
H25.0
ICD-10 Finland
Senile incipient cataract
3.1
74.1
320
1063
S01EE01
ATC
latanoprost; ophthalmic
3.3
73.1
290
916
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.4
73.0
184
424
H26.2
ICD-10 Finland
Complicated cataract
6.1
70.6
124
208
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
70.0
521
2285
H50.1
ICD-10 Finland
Divergent concomitant strabismus
169.2
64.1
67
*
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
3.9
62.8
188
493
XCH00
NOMESCO Finland
Eye pressure measurement
3.0
62.5
284
971
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
3.7
60.2
193
531
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
4.2
59.1
161
394
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.4
58.2
214
644
S01EA05
ATC
brimonidine; ophthalmic
4.7
56.1
129
276
S01EC04
ATC
brinzolamide; ophthalmic
3.6
55.5
183
513
H40.11
ICD-10 Finland
Low pressure glaucoma
5.1
55.3
118
237
H50.30
ICD-10 Finland
Intermittent esotropy
119.1
54.9
59
5
S01ED01
ATC
timolol; ophthalmic
3.8
54.6
166
440
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
53.2
51
*
S01EE05
ATC
tafluprost; ophthalmic
3.5
50.5
176
512
CG2T4
NOMESCO Finland
Topography assessment of cornea
5.7
47.8
89
158
CKC10
NOMESCO Finland
Local photocoagulation of retina
4.6
44.7
107
237
S01BA07
ATC
fluorometholone; ophthalmic
4.0
44.0
126
320
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
5.1
43.9
92
182
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.9
40.9
119
306
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
4.8
40.6
91
191
CKC30
NOMESCO Finland
Cryopexy of detached retina
8.4
40.3
52
62
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
3.8
39.7
123
331
Z3229
NOMESCO Finland
Other healthcare associate professional
2.0
38.8
425
2165
CKC60
NOMESCO Finland
Local buckling of sclera using implant
8.1
38.8
52
65
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.5
38.1
135
397
CEC00
NOMESCO Finland
Recession of extraocular muscle
379.7
38.1
38
*
CS494
NOMESCO Finland
Other visual field testing
3.2
35.6
141
445
S01EC01
ATC
acetazolamide; systemic
3.5
35.6
124
361
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
4.0
34.7
99
251
S01EE03
ATC
bimatoprost; ophthalmic
3.8
34.0
105
282
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
7.5
33.9
48
64
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
5.4
33.7
66
123
CHD00
NOMESCO Finland
Laser trabeculoplasty
6.0
33.7
59
99
ZXA00
NOMESCO Finland
Right side
1.5
33.6
1134
7904
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.1
33.6
141
461
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
5.5
33.4
64
117
WX142
NOMESCO Finland
Sub-tenon anesthesy
6.0
33.2
58
97
H25.8
ICD-10 Finland
Other senile cataract
2.1
32.7
323
1583
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
6.1
32.3
56
93
CHD35
NOMESCO Finland
Laser goniopuncture
9.8
32.1
37
38
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
7.2
31.7
47
66
H43.3
ICD-10 Finland
Other vitreous opacities
3.4
31.5
111
326
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
4.4
31.2
78
179
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
30.2
29
*
S01EE04
ATC
travoprost; ophthalmic
4.2
30.1
81
197
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.3
30.0
236
1057
H53.4
ICD-10 Finland
Visual field defects
3.3
29.7
114
353
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
6.0
29.3
51
85
CKD40
NOMESCO Finland
Endophotocoagulation of retina
3.9
29.1
86
224
ZXA05
NOMESCO Finland
Left side
1.5
29.1
1028
7215
3503
FHL
Single muscle retroposition
293.3
28.8
29
*
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
28.1
27
*
S01EA03
ATC
apraclonidine; ophthalmic
5.0
27.4
58
116
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
10.0
27.4
31
31
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
9.0
26.8
33
37
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
6.8
26.3
41
61
S01EC54
ATC
brinzolamide, combinations; ophthalmic
4.8
26.1
58
121
H54.7
ICD-10 Finland
Unspecified visual loss
4.9
25.5
56
116
H33.5
ICD-10 Finland
Other retinal detachments
4.6
25.2
59
129
H51.1
ICD-10 Finland
Convergence insufficiency and excess
130.5
24.6
26
*
S01EC03
ATC
dorzolamide; ophthalmic
4.6
24.2
57
125
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
9.1
23.8
29
32
H52.5
ICD-10 Finland
Disorders of accommodation
28.3
23.1
31
11
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.7
22.9
475
2938
Z3231
NOMESCO Finland
Registered nurse
1.4
22.3
1372
10598
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
80.4
21.7
24
*
S01BC03
ATC
diclofenac; ophthalmic
2.8
21.5
111
408
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.7
21.2
443
2745
CKC70
NOMESCO Finland
Circular buckling of sclera
9.0
21.2
26
29
H27.1
ICD-10 Finland
Dislocation of lens
9.0
21.2
26
29
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
21.1
586
3888
Z2221
NOMESCO Finland
Medical doctor
1.3
20.8
1478
11654
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.0
20.7
219
1102
S01AX11
ATC
[U] ofloxacin
2.3
20.5
154
677
S01GX01
ATC
cromoglicic acid; ophthalmic
1.4
20.5
1279
9885
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
20.5
353
2077
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
7.8
20.4
28
36
H47.2
ICD-10 Finland
Optic atrophy
6.1
20.3
35
58
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
6.1
19.8
34
56
SMILE, ,
NOMESCO Finland
+∞
19.8
19
*
S01BA04
ATC
prednisolone; ophthalmic
2.7
19.7
102
376
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
4.1
19.6
53
130
F29
ICPC
Eye symptom/complaint other
1.5
19.6
610
4150
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
19.0
1193
9214
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
3.5
18.7
62
176
H52.0
ICD-10 Finland
Hypermetropia
3.3
18.7
69
210
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
100.3
18.6
20
*
WX002
NOMESCO Finland
Sedation and analgesia
1.4
18.5
812
5903
H02AB09
ATC
hydrocortisone; systemic
2.2
18.1
148
675
3507
FHL
Retroposition and resection
180.5
17.5
18
*
P85
ICPC
Mental retardation
6.7
16.6
26
39
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.5
16.5
507
3435
XCH05
NOMESCO Finland
Eye pressure longterm registration
3.9
16.1
47
122
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.4
16.1
111
471
S01EX03, ,
ATC
3.6
16.1
53
150
H16.9
ICD-10 Finland
Keratitis, unspecified
2.4
15.9
108
456
F28
ICPC
Limited function/disability (F)
4.4
15.9
39
89
Z31.5
ICD-10 Finland
Genetic counselling
1.6
15.7
367
2337
S01EE51
ATC
latanoprost and netarsudil; ophthalmic
6.6
15.7
25
38
H35.37
ICD-10 Finland
Macular holes
3.4
15.7
56
167
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
2.9
15.7
73
255
3782B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS DIVERGENS INTERMITTENS]
+∞
15.6
15
*
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
4.7
15.4
35
75
E0000UV, ,
ATC
1.2
15.3
2424
21017
N03AX11
ATC
topiramate; oral
2.0
15.2
166
846
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
15.2
1162
9212
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
6.8
14.8
23
34
H16.0
ICD-10 Finland
Corneal ulcer
1.7
14.8
284
1721
CA1ME
NOMESCO Finland
Ultrasound oculometry
5.0
14.8
31
62
F05
ICPC
Visual disturbance other
1.9
14.6
171
893
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
+∞
14.6
14
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
14.6
14
*
G47.3
ICD-10 Finland
Sleep apnoea
1.3
14.6
1074
8463
XCW10
NOMESCO Finland
Assessment of vision
2.9
14.6
65
222
H40.9
ICD-10 Finland
Glaucoma, unspecified
3.1
14.5
60
196
N05BA01
ATC
diazepam; systemic, rectal
1.4
14.5
573
4082
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
3.6
14.4
47
132
H54.5
ICD-10 Finland
Severe visual impairment, monocular
4.7
14.4
33
71
H50.9
ICD-10 Finland
Strabismus, unspecified
12.5
14.3
25
20
XA800
NOMESCO Finland
Neuropsychological investigation
1.8
14.3
221
1262
37600
ICD-8 Finland
Detachment of retina, Primaria
19.1
14.2
21
11
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
3.0
14.2
60
199
N06AX11
ATC
mirtazapine; oral
1.3
14.1
1803
15225
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
5.1
14.1
29
57
R51.80
ICD-10 Finland
Headache
1.3
14.1
996
7801
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.5
14.0
432
2928
N03AG01
ATC
valproic acid; systemic, rectal
1.6
14.0
308
1935
ZXE00
NOMESCO Finland
One hour or less
1.2
13.9
2019
17292
G35
ICD-10 Finland
Multiple sclerosis
2.3
13.9
108
484
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
2.6
13.9
81
319
F43
ICPC
Eye, Other diagnostic procedure
2.3
13.8
99
429
L03AB08
ATC
interferon beta-1b; parenteral
4.9
13.8
30
62
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.8
13.6
194
1081
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
13.5
13
*
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
4.5
13.5
32
71
AA1AD
NOMESCO Finland
CT of head and brain
1.3
13.3
1082
8630
N05AX08
ATC
risperidone; systemic
1.5
13.3
364
2405
XKC03
NOMESCO Finland
Water cystometry
2.1
13.3
118
558
L03AX13
ATC
glatiramer acetate; parenteral
3.5
13.1
45
131
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
13.0
12.9
22
17
H17.8
ICD-10 Finland
Other corneal scars and opacities
5.3
12.7
25
47
TAB00
NOMESCO Finland
Lumbar puncture
1.7
12.6
239
1445
N03AX09
ATC
lamotrigine; oral
1.6
12.5
322
2100
S01BC05
ATC
ketorolac; ophthalmic
2.1
12.5
114
546
Z94.7
ICD-10 Finland
Corneal transplant status
5.0
12.4
26
52
WX199
NOMESCO Finland
Other local analgesia
2.0
12.4
129
649
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
12.4
1224
10007
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
1.8
12.3
176
982
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.3
12.3
860
6715
183
Kela drug reimbursment
Lamotrigin and topiramate
2.7
12.3
62
227
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.4
12.2
726
5533
Q87.4
ICD-10 Finland
Marfan syndrome
10.5
12.2
23
22
K07.60
ICD-10 Finland
Snapping jaw
1.5
12.2
340
2256
R42
ICD-10 Finland
Dizziness and giddiness
1.3
12.2
1009
8061
CS2P4
NOMESCO Finland
Optic nerve head imaging
3.5
12.1
40
114
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.4
12.0
632
4726
N03AE01
ATC
clonazepam; systemic
1.6
12.0
248
1534
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
3.3
12.0
45
139
Z2446
NOMESCO Finland
Social worker
1.5
11.9
346
2317
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
11.9
681
5161
F83
ICD-10 Finland
Mixed specific developmental disorders
3.0
11.8
50
166
H02.4
ICD-10 Finland
Ptosis of eyelid
2.1
11.8
114
558
109
Kela drug reimbursment
Multiple sclerosis
2.3
11.8
85
370
XCD20
NOMESCO Finland
Photoangiography of eye
2.7
11.7
59
216
H53.3
ICD-10 Finland
Other disorders of binocular vision
3.9
11.7
33
84
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
2.5
11.7
74
304
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
3.4
11.6
41
122
ZXD20
NOMESCO Finland
Day surgery
1.4
11.6
592
4405
CD2S4
NOMESCO Finland
Photography of eye
3.7
11.5
35
94
A10AB01
ATC
insulin (human); parenteral
1.8
11.5
181
1041
CJA00
NOMESCO Finland
Implantation of phakic lens in anterior chamber
+∞
11.5
11
*
602
Kela drug reimbursment
Children's severe malnutrition
3.8
11.4
34
90
N18.8
ICD-10 Finland
Other chronic renal failure
2.4
11.4
75
313
S01FA01
ATC
atropine; ophthalmic
4.7
11.4
26
56
A10AB04
ATC
insulin lispro; parenteral
1.8
11.4
168
948
N06AB04
ATC
citalopram; systemic
1.3
11.3
986
7926
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.4
11.3
660
5016
G40.9
ICD-10 Finland
Epilepsy, unspecified
1.9
11.3
148
805
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
15.0
11.3
18
12
H50.8
ICD-10 Finland
Other specified strabismus
35.1
11.3
14
*
F93
ICPC
Glaucoma
4.9
11.2
24
49
H26.9
ICD-10 Finland
Cataract, unspecified
2.6
11.2
61
233
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
4.1
11.1
30
74
N05AH04
ATC
quetiapine; oral
1.3
11.1
1032
8365
H20.1
ICD-10 Finland
Chronic iridocyclitis
2.6
11.0
62
241
H53.8
ICD-10 Finland
Other visual disturbances
2.4
10.9
72
301
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
3.0
10.9
46
153
A02BC03
ATC
lansoprazole; oral
1.3
10.9
1156
9518
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
10.9
974
7855
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.5
10.8
354
2430
UDC00
NOMESCO Finland
Ear microscopy
1.5
10.8
344
2348
H54.3
ICD-10 Finland
Mild or no visual impairment, binocular
5.1
10.8
22
43
A02BA02
ATC
ranitidine; systemic
1.3
10.7
677
5204
CKD20
NOMESCO Finland
Removal of vitreous body substitute
4.0
10.7
29
72
Z2445
NOMESCO Finland
Psychologist
1.6
10.7
252
1613
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
10.6
2027
17740
CJA10
NOMESCO Finland
Implantation of phakic lens in posterior chamber
60.1
10.6
12
*
H40
ICD-10 Finland
Glaucoma
3.4
10.5
37
110
N03AX14
ATC
levetiracetam; systemic
1.9
10.4
124
654
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
10.4
10
*
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
10.4
10
*
Z3226
NOMESCO Finland
Physiotherapist
1.3
10.4
793
6259
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.5
10.4
340
2336
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.1
10.3
100
491
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
1.9
10.3
133
722
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.6
10.2
226
1423
H26.3
ICD-10 Finland
Drug-induced cataract
3.4
10.2
36
107
L17
ICPC
Foot/toe symptom/complaint
1.2
10.2
1558
13329
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.5
10.2
367
2569
CKD15
NOMESCO Finland
Injection of vitreous substitute
4.5
10.0
24
54
ZYC01
NOMESCO Finland
Remote contact by phone
1.5
10.0
329
2264
H26.8
ICD-10 Finland
Other specified cataract
3.0
10.0
43
145
CGD99
NOMESCO Finland
Other operation for error of refraction
40.1
10.0
12
*
H01AC01
ATC
somatropin; parenteral
3.6
9.9
32
90
XKD00
NOMESCO Finland
Uroflowmetry
1.4
9.9
397
2836
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.8
9.9
131
717
S01ED02
ATC
betaxolol; ophthalmic
3.7
9.8
30
81
WX402
NOMESCO Finland
General anaesthesia
1.2
9.8
1181
9849
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
2.4
9.8
65
273
N05CF02
ATC
zolpidem; oral
1.3
9.8
844
6766
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
1.8
9.8
151
865
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.0
9.8
98
488
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
1.6
9.7
215
1355
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.2
9.7
1259
10583
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
13.4
9.7
16
12
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
2.9
9.6
43
148
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
1.6
9.6
230
1478
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.4
9.6
461
3397
353
Kela drug reimbursment
Cladribine and fingolimod
3.5
9.5
31
88
H57.1
ICD-10 Finland
Ocular pain
1.6
9.4
227
1460
F84.5
ICD-10 Finland
Asperger syndrome
2.4
9.4
64
272
3680A
ICD-9 Finland
Visual disturbances, Amblyopia ex anopsia
30.0
9.4
12
*
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
9.4
9
*
3602A
ICD-9 Finland
Disorders of the globe, Degenerative disorders of globe[MYOPIA MALIGNA]
+∞
9.4
9
*
H18.6
ICD-10 Finland
Keratoconus
3.0
9.4
39
129
U04
ICPC
Incontinence urine
1.6
9.3
185
1135
ZY010
NOMESCO Finland
Hospital outpatient
1.5
9.3
323
2245
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.4
9.3
363
2579
Z83.5
ICD-10 Finland
Family history of eye and ear disorders
4.9
9.3
20
41
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
4.9
9.3
20
41
H18.7
ICD-10 Finland
Other corneal deformities
9.5
9.2
18
19
R5140
NOMESCO Finland
Monitoring the use of the aid
1.4
9.2
439
3234
A10AA01, ,
ATC
1.8
9.1
129
721
H33
ICD-10 Finland
Retinal detachments and breaks
4.8
9.0
20
42
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
4.0
9.0
25
63
164
Kela drug reimbursment
Fingolimod
3.3
9.0
32
96
N03AX12
ATC
[U] gabapentin; oral
1.3
9.0
676
5323
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
1.5
9.0
269
1816
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
1.9
9.0
113
609
N86
ICPC
Multiple sclerosis
2.9
8.9
40
138
Q87.09
ICD-10 Finland
Other congenital malformations that mainly affect the appearance of the face
24.0
8.9
12
5
M08.9
ICD-10 Finland
Juvenile arthritis, unspecified
3.9
8.9
25
64
ZXE10
NOMESCO Finland
More than one and less than three hours
1.2
8.8
1568
13587
3661A
ICD-9 Finland
Cataract, Senile cataract
4.5
8.8
21
47
R01AD01
ATC
beclometasone; nasal
1.3
8.8
727
5797
3745
FHL
Hard membrane girding, cerclage with coagulation
10.7
8.8
16
15
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
8.8
405
2966
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.5
8.7
269
1829
H81
ICPC
Excessive ear wax
1.3
8.7
633
4964
CHW99
NOMESCO Finland
Other operation on anterior chamber, anterior chamber angle, iris or ciliary body
50.1
8.7
10
*
N06AX21
ATC
duloxetine; oral
1.3
8.6
605
4719
EJC20
NOMESCO Finland
Operation on frenulum of tongue
3.5
8.6
29
84
SPAT1009
SPAT
Measurement of intraocular pressure
2.5
8.6
50
198
H04AA01
ATC
glucagon; nasal, parenteral
1.7
8.6
150
891
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.6
8.6
212
1373
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
2.6
8.6
46
175
TCG10
NOMESCO Finland
Removal of sutures from cornea
3.9
8.6
24
61
C07AA05
ATC
propranolol; systemic
1.2
8.6
1110
9321
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.3
8.6
681
5403
G43.3
ICD-10 Finland
Complicated migraine
1.8
8.5
124
699
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
1.6
8.5
193
1225
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
8.5
1525
13219
G44.2
ICD-10 Finland
Tension-type headache
1.3
8.5
772
6231
R4110
NOMESCO Finland
Physiotherapy
1.2
8.4
1234
10489
XF400
NOMESCO Finland
ECG with 12 standard connections
1.3
8.4
548
4230
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
1.5
8.4
281
1940
3504
FHL
Retroposition of two muscles
90.2
8.4
9
*
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
8.3
8
*
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
+∞
8.3
8
*
R35
ICD-10 Finland
Polyuria
1.5
8.3
231
1536
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.5
8.3
252
1707
G04BD12
ATC
mirabegron; oral
1.4
8.3
364
2642
SPAT1260
SPAT
Consultation of another employee
1.3
8.3
792
6425
A98
ICPC
Health maint/preventive medicine
1.6
8.3
6274
61736
RL140, ,
NOMESCO Finland
9.4
8.3
16
17
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
3.0
8.3
34
112
UKC02
NOMESCO Finland
Cystoscopy
1.3
8.2
467
3534
R20.2
ICD-10 Finland
Paraesthesia of skin
1.4
8.2
378
2768
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
1.9
8.2
99
528
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.5
8.1
235
1576
N05AX12
ATC
aripiprazole; systemic
1.5
8.1
271
1871
R4120
NOMESCO Finland
Occupational therapy
1.5
8.1
288
2012
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
1.5
8.1
287
2004
N06AX16
ATC
venlafaxine; oral
1.3
8.1
808
6587
Q05.2
ICD-10 Finland
Lumbar spina bifida with hydrocephalus
33.4
8.1
10
*
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.4
8.0
446
3363
RT274, ,
NOMESCO Finland
7.2
7.9
18
25
A03FA02
ATC
cisapride; oral, rectal
1.5
7.9
251
1717
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
1.8
7.9
105
577
A10AA02, ,
ATC
1.7
7.9
132
777
TPH07
NOMESCO Finland
Cathetrisation of artery
1.4
7.8
384
2840
OAB50, ,
SPAT
1.4
7.8
320
2295
CKD60
NOMESCO Finland
Anterior vitrectomy
3.6
7.8
25
70
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
7.8
727
5878
N02CC04
ATC
rizatriptan; oral
1.4
7.8
332
2399
FM2CE, ,
NOMESCO Finland
2.7
7.7
39
144
DFF00
NOMESCO Finland
Pure tone audiometry
1.4
7.7
364
2675
WX725
NOMESCO Finland
Noninvasive ventilation
1.5
7.7
239
1627
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
2.7
7.7
40
150
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.7
7.7
123
714
N05CF01
ATC
zopiclone; oral
1.2
7.7
1319
11373
SAA04
NOMESCO Finland
Special examination of mouth
1.4
7.6
278
1956
H27.8
ICD-10 Finland
Other specified disorders of lens
8.0
7.6
16
20
ZXD10
NOMESCO Finland
Scheduled procedure
1.2
7.5
1698
14993
A02BC05
ATC
esomeprazole; systemic
1.2
7.5
1913
17057
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
3.5
7.4
24
68
F50.9
ICD-10 Finland
Eating disorder, unspecified
1.9
7.4
85
446
A10AC01
ATC
insulin (human); parenteral
1.4
7.4
297
2125
A10AE05
ATC
insulin detemir; parenteral
1.5
7.4
217
1462
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
2.1
7.4
64
303
B99
ICPC
Blood/lymph/spleen disease other
3.7
7.3
22
59
A03FA01
ATC
metoclopramide; systemic, rectal
1.2
7.3
1009
8515
J02AC01
ATC
fluconazole; systemic
1.2
7.3
2231
20166
N03AX18
ATC
lacosamide; systemic
2.5
7.3
42
166
N05AF03
ATC
chlorprothixene; systemic
1.7
7.3
120
703
3784B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Heterophoria[EXOPHORIA]
+∞
7.3
7
*
3505
FHL
Single muscle resection
+∞
7.3
7
*
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
7.3
7
*
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
2.9
7.3
32
110
WX780
NOMESCO Finland
Remote monitoring CPAP
1.5
7.3
201
1338
H40.12
ICD-10 Finland
Pigmentary glaucoma
6.2
7.2
18
29
G04BD08
ATC
solifenacin; oral
1.5
7.2
182
1187
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
1.9
7.2
83
436
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.2
7.1
1526
13405
SPAT1262
SPAT
Handing over of treatment supplies
1.3
7.1
610
4885
L04AA06
ATC
mycophenolic acid; systemic
1.9
7.1
89
481
H27.0
ICD-10 Finland
Aphakia
6.0
7.1
18
30
A06AD11
ATC
lactulose; oral
1.3
7.1
454
3501
N05AH02
ATC
clozapine; systemic
1.8
7.0
105
599
S01EB01
ATC
pilocarpine; ophthalmic
4.2
7.0
18
43
N05AH03
ATC
olanzapine; systemic
1.4
7.0
338
2497
R53
ICD-10 Finland
Malaise and fatigue
1.2
7.0
1349
11748
H93.1
ICD-10 Finland
Tinnitus
1.4
7.0
296
2140
E66.8
ICD-10 Finland
Other obesity
1.4
6.9
307
2235
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.4
6.9
292
2108
H43.2
ICD-10 Finland
Crystalline deposits in vitreous body
6.3
6.9
17
27
CKC20
NOMESCO Finland
Cryopexy of undetached retina
5.8
6.9
18
31
CJE99
NOMESCO Finland
Other extracapsular cataract operation using phakoemulsification technique
13.8
6.9
11
8
RT490, ,
NOMESCO Finland
13.8
6.9
11
8
H52
ICD-10 Finland
Disorders of refraction and accommodation
4.0
6.9
19
48
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.2
6.8
897
7530
SPAT1325
SPAT
Vaccination
1.2
6.8
1417
12410
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.3
6.8
369
2775
R55
ICD-10 Finland
Syncope and collapse
1.3
6.8
388
2941
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
10.9
6.8
12
11
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.5
6.8
215
1473
N06AX12
ATC
bupropion; oral
1.3
6.8
477
3726
Q87.80
ICD-10 Finland
Alport syndrome
40.1
6.8
8
*
R62.0
ICD-10 Finland
Delayed milestone
2.7
6.7
34
126
RT271, ,
NOMESCO Finland
5.6
6.7
18
32
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
3.9
6.7
19
49
TCG30
NOMESCO Finland
Imaging of anterior and posterior part of cornea
7.2
6.7
15
21
N05CD07
ATC
temazepam; oral
1.4
6.7
316
2326
H35.8
ICD-10 Finland
Other specified retinal disorders
3.2
6.7
25
78
ZYY79
NOMESCO Finland
Other indirect service without contact with patient
2.7
6.7
33
121
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.3
6.6
417
3205
XF404
NOMESCO Finland
Ambulatory ECG
1.4
6.6
289
2099
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
6.6
1159
9999
CG2Z4
NOMESCO Finland
Specialised imaging of cornea
6.4
6.6
16
25
R06.5
ICD-10 Finland
Mouth breathing
1.3
6.6
407
3120
M03BX01
ATC
baclofen; systemic
1.8
6.6
84
457
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.3
6.6
355
2668
H03AA01
ATC
levothyroxine sodium; systemic
1.2
6.6
1052
9001
3768
FHL
Eye examination under general anesthesia
12.2
6.6
11
9
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.2
6.5
820
6852
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
8.7
6.5
13
15
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
4.2
6.5
17
41
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.5
6.5
209
1435
H35.9
ICD-10 Finland
Retinal disorder, unspecified
3.0
6.5
27
90
N03AX16
ATC
[U] pregabalin
1.2
6.5
934
7916
C08CA01
ATC
amlodipine; oral
1.2
6.4
1243
10815
S82
ICPC
Naevus/mole
1.2
6.4
735
6084
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.3
6.4
567
4558
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
6.4
1862
16735
H43
ICD-10 Finland
Disorders of vitreous body
2.8
6.4
30
107
WX720
NOMESCO Finland
Own respiration
1.5
6.4
197
1344
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
1.7
6.3
103
603
WX892
NOMESCO Finland
Monitored bed care
1.4
6.3
264
1904
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
2.3
6.3
44
191
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.3
6.3
462
3627
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
2.2
6.3
47
210
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
1.8
6.3
80
435
R4130
NOMESCO Finland
Speech therapy
1.7
6.3
101
589
CJF20
NOMESCO Finland
Removal of artificial lens
11.0
6.3
11
10
H26.01
ICD-10 Finland
Infantile, juvenile and presenile cataract
5.5
6.3
17
31
H35.1
ICD-10 Finland
Retinopathy of prematurity
9.2
6.3
12
13
R06AE07
ATC
cetirizine; oral
1.1
6.3
2549
23451
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
18.0
6.3
9
5
Z010, H521,
ICD-10 Finland
+∞
6.2
6
*
3660C
ICD-9 Finland
Cataract, Infantile, juvenile and presenile cataract[CATARACTA PRAESENILIS]
7.0
6.2
14
20
H46
ICD-10 Finland
Optic neuritis
2.1
6.2
53
251
F29
ICD-10 Finland
Unspecified nonorganic psychosis
1.4
6.2
214
1493
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.4
6.2
244
1744
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
2.7
6.2
31
115
N05BA04
ATC
oxazepam; oral
1.2
6.1
1269
11100
N06AB06
ATC
sertraline; oral
1.2
6.1
648
5317
ZXE30
NOMESCO Finland
More than five and less than seven hours
1.5
6.1
161
1062
A02BC01
ATC
omeprazole; systemic
1.2
6.1
1154
10018
R50.9
ICD-10 Finland
Fever, unspecified
1.2
6.1
736
6126
H3601, E103,
ICD-10 Finland
2.2
6.1
50
233
D22
ICD-10 Finland
Melanocytic naevi
1.3
6.1
333
2511
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
2.0
6.0
57
280
N03AA02
ATC
phenobarbital; systemic
8.6
6.0
12
14
K59.1
ICD-10 Finland
Functional diarrhoea
1.4
6.0
245
1759
G04BD09
ATC
trospium; oral
1.9
6.0
65
335
G43.9
ICD-10 Finland
Migraine, unspecified
1.3
6.0
414
3223
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
1.7
6.0
110
665
H47.1
ICD-10 Finland
Papilloedema, unspecified
2.6
6.0
33
128
N88
ICPC
Epilepsy
2.6
6.0
33
128
N05BA09
ATC
clobazam; oral
2.5
6.0
36
146
G40.89
ICD-10 Finland
Other epilepsy
3.2
6.0
23
73
F82
ICD-10 Finland
Specific developmental disorder of motor function
2.7
6.0
30
111

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
3014
25326
1.36
30.64
2.9
2.5
74.41
73.98
nmol/l
0.39
2816
23734
1756
14025
1.35
23.14
4.8
4.1
7.40
7.40
ph
0.07
1239
9808
2488
21089
1.29
20.83
2.1
1.9
98.77
97.86
pmol/l
0.46
1345
11567
2766
23788
1.28
20.60
8.8
6.9
1.22
1.21
mmol/l
0.83
2370
20822
2477
21118
1.28
19.39
8.9
6.4
1.22
1.21
mmol/l
1.70
2306
19727
4892
45463
1.31
18.69
5.1
4.5
14.46
14.47
pmol/l
0.03
4558
42604
2525
21653
1.27
18.62
5.7
5.0
36.98
36.80
g/l
0.94
2359
20444
3270
28958
1.26
18.27
7.8
6.6
0.55
0.55
e9/l
0.57
2923
25264
1104
8473
1.37
18.25
2.9
2.5
14.20
14.24
umol/l
0.06
1021
7950
3272
28994
1.26
18.11
7.8
6.6
0.04
0.04
e9/l
0.79
2916
25277
3590
32200
1.26
17.73
11.0
9.6
3.92
4.00
e9/l
1.47
3196
28094
5512
52239
1.38
17.64
6.1
5.3
1.77
1.79
mu/l
0.58
5235
49607
4350
39936
1.27
17.52
8.3
7.7
75.70
75.82
u/l
0.06
4148
38116
3361
29991
1.25
17.06
8.1
6.8
0.19
0.19
e9/l
0.26
3027
26597
3342
29804
1.25
17.04
7.8
6.6
1.93
1.98
e9/l
2.17
3034
26657
1593
13005
1.30
16.99
1.7
1.6
20.78
20.04
nmol/l
1.30
1387
11402
3010
26554
1.25
16.80
8.0
6.7
2.82
2.81
%
0.14
2858
25087
3005
26517
1.25
16.69
8.1
6.8
0.69
0.68
%
0.24
2853
25005
3013
26608
1.25
16.58
8.1
6.8
8.56
8.47
%
1.08
2863
25165
1015
7796
1.36
16.55
2.9
2.5
2.45
2.42
g/l
0.97
931
7250
779
5757
1.40
16.07
2.3
2.2
374.03
377.65
nmol/l
0.21
725
5360
5672
54177
1.38
15.83
16.6
13.6
139.60
139.65
mmol/l
0.78
5568
53079
5682
54303
1.38
15.67
16.8
13.7
3.93
3.93
mmol/l
0.41
5561
53077
86
333
2.60
15.19
2.8
2.1
2.03
1.86
umol/l
0.99
79
305
923
7075
1.36
15.15
3.0
2.6
23.98
23.70
%
0.25
856
6608
821
6181
1.38
15.10
8.6
6.5
1.08
1.06
mmol/l
1.67
749
5789
3095
27634
1.23
14.65
7.9
6.6
29.52
29.44
%
0.16
2975
26405
3461
31270
1.23
14.60
3.7
3.2
89.10
90.26
ug/l
0.11
3266
29820
77
291
2.67
14.30
1.1
1.1
2.31
6.17
nmol/l
0.70
12
54
3361
30341
1.22
14.05
3.9
3.5
0.03
0.07
estimate
0.32
689
6025
3341
30163
1.22
13.88
3.9
3.5
3.35
5.22
estimate
0.32
722
6278
1986
16983
1.24
13.87
3.6
3.3
2.36
2.35
mmol/l
0.48
1830
15722
3309
29885
1.22
13.55
3.9
3.5
0.00
0.00
estimate
0.03
719
6230
629
4627
1.40
13.24
3.1
2.8
10.30
10.47
g/l
0.62
575
4300
3035
27219
1.22
13.19
7.7
6.5
56.16
56.26
%
0.20
2935
26170
2728
24220
1.22
13.09
3.4
3.1
6.26
6.21
ph
1.18
1464
13929
1115
8950
1.30
13.08
1.5
1.4
463.24
534.52
titre
0.70
222
1805
645
4787
1.39
12.87
3.7
3.0
1.69
1.73
%
0.49
583
4327
1884
16147
1.24
12.63
1.4
1.4
1.88
1.67
u/ml
0.21
527
4652
1640
13854
1.25
12.54
2.5
2.3
2.58
2.64
mg/l
0.47
1411
12114
1196
9747
1.28
12.40
1.7
1.6
46581210.96
36508550.78
pmol/l
0.19
1009
8431
1922
16573
1.23
12.03
3.9
3.5
8.11
8.08
mmol/l
0.09
1706
14508
824
6415
1.33
12.02
1.9
1.7
—
—
—
0
0
274
1738
1.60
11.99
6.8
5.2
1.38
1.31
mg/l
0.55
256
1637
6034
58618
1.45
11.93
17.7
15.1
72.77
71.61
umol/l
1.81
5995
58016
397
2738
1.48
11.86
2.9
2.9
126.80
146.85
ng/l
0.61
362
2439
1665
14165
1.24
11.81
2.5
2.1
253.56
196.61
u/l
0.64
1575
13522
487
3496
1.43
11.77
3.4
2.8
70.77
70.75
e9/l
0.00
347
2490
3316
30193
1.20
11.71
6.4
4.8
6.52
6.42
mmol/l
1.71
3088
27946
1681
14331
1.23
11.66
5.3
4.4
—
—
—
0
0
5192
49443
1.26
11.45
5.8
5.1
37.89
37.69
mmol/mol
0.85
4936
47238
479
3449
1.42
11.38
4.9
4.0
85.27
79.31
ng/l
0.55
407
3075
1645
14027
1.23
11.34
1.6
1.5
2.17
2.20
g/l
0.31
1086
9179
365
2521
1.47
10.84
1.3
1.3
2.36
1.14
u/ml
0.52
34
172
355
2439
1.48
10.82
14.6
10.6
16.14
16.23
%
0.23
345
2348
983
7944
1.28
10.77
4.8
3.9
0.83
0.82
mmol/l
0.35
906
7555
560
4202
1.36
10.40
3.5
3.5
4.57
4.59
pmol/l
0.25
515
3803
2936
26615
1.19
10.37
6.4
6.2
10.78
10.86
umol/l
0.11
2784
25284
834
6635
1.30
10.31
1.9
1.7
1224.08
1160.87
nmol/l
1.20
630
5141
1573
13481
1.22
10.13
3.9
3.6
45.27
54.73
mg/l
0.99
1011
8647
2499
22398
1.19
9.90
2.0
1.8
1.32
1.38
mmol/l
2.91
2161
19639
1589
13662
1.22
9.87
4.7
4.2
7.75
9.43
mg/mmol
0.91
1006
8668
144
821
1.77
9.49
6.8
5.8
403.39
366.89
umol/l
2.30
129
721
1966
17329
1.19
9.26
3.4
2.9
0.42
0.05
estimate
0.43
602
5079
486
3638
1.36
9.17
1.9
1.9
1.27
1.30
g/l
0.12
458
3394
1876
16482
1.19
9.13
2.9
2.7
57.29
62.88
u/l
0.53
1730
15396
2197
19575
1.19
9.11
3.7
3.2
28.17
31.45
u/l
2.66
2093
18632
25
63
3.98
9.03
1.2
1.2
0.79
0.81
iu/ml
0.03
13
28
5132
49158
1.21
8.77
19.0
15.6
13.35
13.36
%
0.26
5075
48518
451
3366
1.37
8.68
1.1
1.1
—
—
—
0
0
106
566
1.89
8.67
1.1
1.1
225.04
238.84
mg/l
0.38
94
504
865
7066
1.26
8.56
3.2
2.4
29.54
29.36
s
0.34
838
6872
5303
50995
1.22
8.53
4.6
4.2
5.74
5.71
mmol/l
0.94
4953
48017
1807
15920
1.19
8.39
4.0
3.6
0.00
0.00
estimate
3.67
673
5906
6005
58648
1.34
8.14
12.1
10.5
26.16
26.48
u/l
0.60
5862
57379
106
583
1.83
7.94
1.2
1.1
35.45
39.05
mg/l
0.65
83
492
2775
25391
1.16
7.94
12.0
10.3
0.00
0.00
e9/l
0.18
2266
20664
1115
9446
1.22
7.83
3.1
2.7
528.31
534.47
mosm/kgh2o
0.38
970
8262
2528
22986
1.16
7.82
3.8
3.3
0.18
0.13
estimate
0.11
616
5205
161
1004
1.62
7.69
4.7
3.4
—
—
—
0
0
1288
11085
1.20
7.66
3.1
2.6
6.64
6.94
e6/l
0.31
1163
10023
439
3328
1.34
7.65
1.2
1.1
58.62
2.08
u/ml
—
5
32
586
4626
1.29
7.64
6.5
4.3
7.37
7.37
ph
0.12
367
2575
1246
10702
1.20
7.57
3.5
3.0
1050.05
925.92
ng/l
0.26
998
8848
274
1924
1.44
7.55
2.3
1.9
0.23
0.23
g/l
0.14
258
1838
5580
54084
1.23
7.49
4.8
4.3
4.64
4.72
mmol/l
8.96
5292
51801
740
6027
1.26
7.49
1.4
1.4
—
—
—
0
0
1028
8680
1.22
7.44
3.9
3.3
614.96
438.30
ng/l
0.40
677
5452
604
4806
1.28
7.41
11.6
8.4
7.42
7.42
ph
1.09
303
2550
516
4024
1.31
7.38
12.3
9.1
123.07
123.09
g/l
0.01
507
3932
5276
50874
1.20
7.37
4.0
3.7
1.24
1.26
mmol/l
1.07
4967
48284
49
208
2.37
7.33
2.1
2.2
16.70
15.59
umol/l
0.36
49
208
602
4795
1.28
7.32
11.4
8.3
5.07
5.08
kpa
0.09
578
4627
602
4796
1.28
7.31
11.4
8.3
13.18
13.18
kpa
0.00
579
4627
202
1344
1.52
7.30
3.4
3.3
57.58
57.62
%
0.01
202
1344
25
74
3.39
7.23
1.1
1.2
1.91
1.70
iu/ml
—
10
34
3835
36080
1.15
7.21
4.9
4.1
1662.58
1754.25
e6/l
0.03
55
418
5613
54482
1.23
7.16
5.3
4.7
2.75
2.82
mmol/l
8.85
5317
51965
462
3565
1.32
7.14
4.7
3.7
1.23
1.23
mmol/l
0.43
385
3087
568
4514
1.28
7.04
2.3
2.3
12.50
12.40
nmol/l
0.09
523
4144
233
1613
1.46
6.95
5.3
5.2
0.90
0.90
%
0.04
222
1512
58
271
2.15
6.94
2.0
2.2
0.21
0.20
e9/l
0.08
24
133
277
1982
1.42
6.91
2.3
1.9
1.20
1.19
g/l
0.24
265
1899
575
4592
1.28
6.85
6.4
4.3
5.85
5.84
kpa
0.10
562
4455
230
1594
1.46
6.83
1.1
1.1
—
—
—
0
0
2200
19945
1.16
6.82
4.4
3.7
62.79
75.55
e6/l
0.41
1481
13276
148
933
1.60
6.81
5.7
3.5
2.40
2.28
mmol/l
0.23
110
573
84
456
1.85
6.63
1.3
1.2
0.61
0.66
ratio
0.76
50
276
846
7088
1.22
6.58
1.3
1.2
—
—
—
0
0
559
4473
1.27
6.56
6.5
4.4
1.57
1.67
mmol/l
0.28
483
3885
591
4764
1.26
6.53
11.6
8.3
0.84
0.72
mmol/l
0.33
488
3880
1078
9252
1.20
6.52
2.6
2.7
102.81
115.60
ug/g
0.67
882
7419
221
1536
1.45
6.48
2.6
2.4
549.19
387.62
ug/l
0.29
201
1429
89
496
1.81
6.47
14.4
16.9
822.95
3404.08
nmol/l
0.50
83
483
249
1772
1.42
6.43
5.0
4.9
1.73
1.68
%
0.28
238
1663
1506
13320
1.17
6.39
4.7
4.1
94.17
93.93
%
0.16
1458
13013
518
4121
1.28
6.38
12.6
8.3
1.31
1.30
mmol/l
0.11
506
4048
103
602
1.72
6.37
2.6
2.5
1342.61
1280.15
e6/l
0.29
82
504
91
514
1.78
6.34
21.9
22.5
1407.87
3235.64
nmol/l
0.50
85
501
499
3955
1.28
6.33
12.1
8.4
8.15
8.12
mmol/l
0.04
486
3820
541
4335
1.27
6.28
2.2
2.4
22.32
19.33
au/ml
0.27
49
575
795
6651
1.22
6.26
1.6
1.5
—
—
—
0
0
558
4490
1.27
6.26
5.0
4.5
0.44
0.64
%
2.33
149
1202
1039
8924
1.20
6.22
2.8
2.7
2.43
2.43
mmol/l
0.10
919
8020
530
4242
1.27
6.22
12.2
8.8
95.57
96.07
%
0.70
512
4097
2208
20149
1.15
6.06
11.0
10.3
1.16
1.15
inr
0.51
1821
16706
5539
53851
1.20
6.04
4.8
4.3
1.47
1.47
mmol/l
0.12
5242
51386
1823
16417
1.15
6.04
3.7
3.1
54.66
73.90
e6/l
0.41
1386
12196
4363
41649
1.15
6.03
3.6
3.2
38.20
38.83
u/l
0.27
4148
39976
518
4151
1.27
6.02
14.8
9.4
—
—
—
0
0
217
1526
1.44
6.01
1.4
1.3
36.82
44.22
u/ml
0.21
16
133
1324
11642
1.17
6.00
1.4
1.3
24.84
26.94
iu/ml
0.24
401
3412
188
1291
1.47
5.91
5.7
5.6
1.26
1.28
mmol/l
0.13
170
1131
1818
16397
1.15
5.86
6.6
6.3
—
—
—
0
0
252
1829
1.39
5.85
2.0
2.1
3.55
6.65
iu/l
0.55
103
830
504
4040
1.27
5.85
1.2
1.3
50.05
48.06
au/ml
0.07
20
244
1911
17302
1.15
5.83
2.8
2.7
0.08
0.04
0.21
25
260
6277
61974
1.45
5.83
23.4
19.6
6.57
6.70
e9/l
5.46
6177
60812
6275
61953
1.45
5.80
23.3
19.5
30.07
30.10
pg
0.69
6230
61511
414
3242
1.30
5.78
2.4
2.6
67.32
67.04
g/l
0.32
390
3034
6273
61933
1.44
5.76
23.4
19.6
261.05
260.73
e9/l
0.15
6183
60902
6275
61957
1.45
5.75
24.2
20.0
41.23
41.36
%
0.08
6227
61479
1587
14193
1.16
5.74
3.6
3.0
0.34
0.32
e6/l
0.14
1156
10082
83
471
1.77
5.73
2.7
2.6
213.46
210.82
e6/l
0.04
61
376
81
457
1.78
5.70
2.5
2.5
469.33
526.79
e6/l
0.58
57
351
6274
61950
1.44
5.70
23.3
19.5
90.07
90.14
fl
0.70
6228
61506
6275
61962
1.44
5.70
23.3
19.6
4.55
4.55
e12/l
0.14
6172
60827
325
2474
1.33
5.58
2.1
2.3
—
—
—
0
0
306
2313
1.34
5.52
2.9
2.5
20.48
20.77
s
0.66
260
2007
6275
61981
1.43
5.48
23.6
19.7
135.98
136.11
g/l
0.36
6230
61533
125
801
1.57
5.46
1.3
1.3
91.27
56.41
u/ml
—
6
48
185
1291
1.45
5.38
1.4
1.6
—
—
—
0
0
262
1942
1.36
5.38
1.4
1.3
49.43
37.72
u/ml
0.26
20
110
570
4681
1.24
5.37
4.3
3.5
—
—
—
0
0
5728
55969
1.21
5.33
15.2
12.9
21.01
21.31
mg/l
0.27
4642
45034
651
5429
1.22
5.29
1.3
1.3
153.72
143.97
u/ml
0.25
258
2067
111
700
1.60
5.20
1.9
1.6
—
—
—
0
0
111
700
1.60
5.20
1.9
1.6
—
—
—
0
0
111
700
1.60
5.20
1.9
1.6
—
—
—
0
0
111
700
1.60
5.20
1.9
1.6
—
—
—
0
0
196
1392
1.42
5.20
1.5
1.6
21600.78
880.65
e6/l
0.58
162
1077
569
4689
1.23
5.19
5.6
4.7
0.69
0.85
%
0.93
146
1250
569
4695
1.23
5.13
1.4
1.3
190.62
229.90
u/ml
0.48
533
4380
193
1373
1.42
5.08
1.4
1.6
41.94
27.35
e6/l
0.42
147
993
259
1936
1.35
5.06
4.3
3.1
3.60
3.55
g/l
0.22
248
1842
127
833
1.54
5.03
6.4
7.0
10.96
11.40
mmol/l
0.88
119
745
127
834
1.53
5.01
6.4
7.0
104.78
105.34
mmol/l
0.61
119
746
381
3010
1.28
5.01
6.2
4.0
7.41
7.41
ph
0.57
322
2470
1497
13449
1.15
4.99
3.5
3.4
0.21
0.17
0.10
14
106
110
700
1.58
4.98
2.6
1.8
1.75
1.69
mmol/l
0.30
110
685
242
1795
1.36
4.97
1.4
1.3
10.01
10.40
u/ml
0.03
36
243
247
1838
1.36
4.97
1.5
1.3
—
—
—
0
0
194
1387
1.41
4.97
1.2
1.5
3.62
3.63
mmol/l
0.05
186
1319
390
3097
1.28
4.92
6.2
4.0
5.15
5.13
kpa
0.19
374
2988
546
4518
1.23
4.80
5.8
4.8
0.04
0.11
%
2.85
125
1080
241
1798
1.35
4.79
1.4
1.3
5.89
6.48
u/ml
0.07
32
153
87
529
1.65
4.75
2.4
1.8
89.75
90.59
%
0.75
87
524
122
806
1.52
4.71
2.0
1.5
20.08
13.04
u/ml
—
5
19
212
1556
1.37
4.68
1.3
1.5
438.54
499.25
mg/l
1.76
200
1494
1528
13805
1.14
4.65
3.6
2.9
1.67
66.98
estimate
—
6
40
558
4646
1.22
4.63
6.0
5.0
1.49
0.25
%
0.89
127
1040
116
763
1.53
4.58
1.8
1.6
61.46
74.47
mu/l
0.34
105
697
1649
14986
1.13
4.57
3.2
2.7
—
—
—
0
0
77
459
1.69
4.55
1.2
1.2
—
—
—
0
0
1358
12189
1.14
4.54
4.6
4.1
—
—
—
0
0
83
506
1.65
4.51
2.6
2.1
1.01
0.88
%
1.17
57
320
369
2957
1.26
4.36
6.9
4.7
23.98
24.15
mmol/l
0.54
364
2927
468
3855
1.23
4.32
5.7
3.9
4.66
4.70
kpa
0.17
456
3735
103
670
1.55
4.30
1.3
1.4
3.12
2.96
g/l
0.44
76
477
103
670
1.55
4.30
1.3
1.4
6.20
6.53
g/l
0.63
79
476
103
670
1.55
4.30
1.3
1.4
0.36
0.38
g/l
0.24
79
470
159
1129
1.42
4.29
1.1
1.1
—
—
—
0
0
2683
25187
1.11
4.16
2.9
2.6
—
—
—
0
0
21
79
2.66
4.15
2.0
1.6
—
—
—
0
0
100
657
1.53
4.02
1.3
1.4
—
—
—
0
0
1192
10705
1.14
3.92
1.4
1.3
9.04
8.78
u/ml
0.05
462
4472
485
4054
1.21
3.90
1.3
1.2
—
—
—
0
0
330
2650
1.26
3.86
2.2
2.0
10.24
6.69
iu/ml
0.97
77
647
132
926
1.43
3.85
2.0
2.1
6.22
5.31
mmol/24h
0.63
122
842
432
3579
1.22
3.81
1.2
1.2
—
—
—
0
0
47
257
1.83
3.79
2.3
2.1
76.16
97.14
ng/l
1.60
47
257
1478
13486
1.12
3.75
3.6
3.4
1.02
1.37
kg/l
1.08
927
8730
24
102
2.36
3.73
4.8
7.2
5.21
5.64
kpa
0.65
24
102
332
2686
1.25
3.66
5.4
3.6
131.09
131.82
g/l
0.24
321
2611
812
7136
1.16
3.64
2.2
2.0
—
—
—
0
0
230
1780
1.30
3.63
4.9
3.4
25.20
25.30
mmol/l
0.18
222
1704
307
2465
1.26
3.62
7.3
6.6
24.63
24.33
mmol/l
0.66
295
2352
82
529
1.56
3.61
2.7
3.1
—
—
—
0
0
32
156
2.06
3.60
2.2
2.4
2.41
2.74
mmol/l
0.39
27
146
164
1210
1.36
3.59
5.4
4.0
66.38
63.04
%
1.29
157
1175
1847
17124
1.11
3.49
3.5
3.1
57.54
89.92
ng/l
0.36
1007
9226
312
2523
1.25
3.47
16.5
10.8
24.26
24.15
mmol/l
0.25
302
2487
599
5167
1.18
3.42
1.5
1.4
21.54
23.86
iu/l
1.09
497
4397
94
636
1.49
3.35
2.1
2.4
21.70
21.26
nmol/l
0.12
87
612
55
328
1.68
3.34
2.7
2.8
46.56
44.00
%
0.45
31
168
150
1108
1.36
3.29
1.1
1.1
—
—
—
0
0
189
1450
1.31
3.23
1.5
1.4
265.33
300.76
ug/g
1.29
94
770
635
5537
1.16
3.17
1.2
1.2
—
—
—
0
0
139
1022
1.37
3.16
1.1
1.1
115.76
116.04
%
0.04
119
939
101
706
1.44
3.08
2.5
1.5
66.16
62.98
mmol/l
0.26
85
564
10
25
4.00
3.08
1.7
2.0
353.70
254.76
ug/l
—
10
25
239
1905
1.26
3.05
2.0
1.9
1.40
1.45
g/l
0.31
209
1670
339
2809
1.22
3.04
1.5
1.5
9.67
9.29
u/l
0.18
270
2253
194
1507
1.30
3.04
2.5
2.2
10.38
11.01
mg/l
0.53
179
1428
87
593
1.47
3.03
1.1
1.1
1.17
2.19
u/ml
0.64
29
201
101
709
1.43
3.02
1.4
1.4
344.64
503.34
pmol/l
0.55
84
621
24
114
2.11
2.93
1.0
1.0
0.19
0.11
u/ml
0.19
15
69
233
1863
1.26
2.92
1.1
1.1
6.11
5.89
eliau/ml
0.03
30
282
65
420
1.55
2.91
3.5
3.5
14.24
14.67
index
0.10
51
284
1041
9438
1.12
2.91
4.7
4.4
1.86
2.06
ug/l
0.80
943
8648
184
1430
1.30
2.89
1.9
1.5
136.12
146.07
au/ml
0.43
45
398
63
405
1.56
2.89
1.2
1.1
—
—
—
0
0
166
1276
1.31
2.84
2.1
2.4
10.16
10.32
g/l
0.15
155
1169
79
536
1.48
2.84
1.5
1.6
286.69
282.48
mosm/kgh2o
1.31
58
425
417
3549
1.19
2.83
1.1
1.2
221.82
179.91
titre
0.14
11
113
11
33
3.34
2.80
2.6
6.2
102.36
102.45
g/l
0.01
11
33
38
217
1.76
2.75
5.6
4.7
—
—
—
0
0
70
468
1.50
2.71
1.1
1.2
143.81
115.51
pmol/l
0.95
70
468
110
801
1.38
2.71
2.3
2.3
—
—
—
0
0
440
3782
1.18
2.67
1.6
1.6
328.07
302.15
mu/l
0.67
391
3403
1379
12752
1.10
2.67
2.1
1.9
1.05
1.04
mg/l
0.03
1024
9570
30
161
1.87
2.65
1.0
1.1
—
—
—
0
0
30
161
1.87
2.65
1.0
1.1
—
—
—
0
0
30
161
1.87
2.65
1.0
1.1
—
—
—
0
0
1401
12971
1.10
2.64
2.8
2.5
325.10
323.34
umol/l
0.28
1267
11821
136
1028
1.33
2.64
1.2
1.2
—
—
—
0
0
118
875
1.36
2.61
2.9
2.6
117.80
111.48
ug/min
0.06
70
553
18
80
2.25
2.60
1.2
1.5
—
—
—
0
0
190
1506
1.27
2.60
2.0
2.3
4.27
4.27
g/l
0.00
180
1407
170
1331
1.28
2.57
2.9
2.9
4.61
2.14
index
1.36
103
711
5
7
7.15
2.55
1.0
1.0
—
—
—
0
0
131
991
1.33
2.54
2.5
2.6
27.51
28.90
iu/ml
—
7
67
78
542
1.44
2.52
3.0
3.3
27.70
26.93
mu/l
0.06
73
508
189
1504
1.26
2.51
2.0
2.3
3.59
3.74
g/l
0.91
179
1407
279
2319
1.21
2.49
1.2
1.2
—
—
—
0
0
9
26
3.46
2.48
3.6
4.0
—
—
—
0
0
189
1507
1.26
2.48
2.0
2.3
7.14
7.29
g/l
0.67
179
1407
181
1439
1.27
2.43
2.0
2.3
2.74
2.90
g/l
1.56
171
1340
72
499
1.45
2.38
12.0
13.6
0.68
0.59
mmol/l
1.16
64
459
145
1125
1.30
2.37
2.8
3.5
46.68
53.01
mg/l
0.31
110
959
12
46
2.61
2.35
1.0
1.1
1.44
1.63
umol/24h
0.49
12
46
44
275
1.60
2.33
1.2
1.1
—
—
—
0
0
84
604
1.40
2.28
1.1
1.1
5.98
7.68
u/ml
0.08
24
165
144
1125
1.29
2.25
2.8
3.5
55.11
48.24
mg/l
0.11
110
963
185
1491
1.25
2.24
2.1
2.0
2.23
1.84
ug/l
0.20
171
1338
17
79
2.15
2.24
1.0
1.1
0.63
0.71
umol/24h
0.49
12
44
960
8796
1.11
2.23
3.1
2.7
1.03
1.05
e6/l
0.05
484
4441
139
1083
1.29
2.23
1.3
1.7
0.59
0.74
g/l
1.68
102
844
29
165
1.76
2.18
2.1
2.8
28.41
28.22
umol/l
0.03
21
116
26
143
1.82
2.18
1.1
1.1
—
—
—
0
0
26
143
1.82
2.18
1.1
1.1
—
—
—
0
0
26
143
1.82
2.18
1.1
1.1
—
—
—
0
0
188
1525
1.24
2.16
1.9
1.5
—
—
—
0
0
7
19
3.69
2.15
1.0
1.3
39.17
27.97
mg/24h
—
7
19
141
1107
1.28
2.14
2.4
2.3
135.40
132.19
g/l
0.90
122
902
290
2458
1.19
2.14
1.6
1.7
11.45
11.41
u/ml
0.01
84
698
139
1091
1.28
2.12
1.2
1.3
3.11
4.22
u/ml
1.07
72
503
5127
50334
1.09
2.12
19.2
15.9
333.26
333.07
g/l
0.84
5106
50068
171
1377
1.25
2.11
1.7
1.4
3.05
7.26
iu/ml
—
6
25
50
331
1.51
2.10
1.0
1.1
—
—
—
0
0
40
253
1.58
2.06
22.2
28.9
141.14
119.38
ug/l
1.04
29
207
48
318
1.51
2.02
1.3
1.2
89.29
75.67
%
—
7
33
187
1529
1.23
2.02
1.9
1.4
25.82
18.34
u/ml
—
6
28
78
568
1.38
2.01
9.8
6.8
11.38
11.16
mg/l
0.16
71
531
127
995
1.28
1.99
2.9
3.4
1.96
3.12
ratio
0.76
69
553
34
209
1.63
1.97
2.4
2.2
27.97
29.72
%
0.36
34
209
256
2166
1.19
1.96
2.2
2.3
—
—
—
0
0
33
202
1.64
1.94
2.4
2.2
10.27
8.58
%
0.36
33
197
66
471
1.41
1.92
1.3
1.2
1.93
1.94
mmol/l
0.02
61
439
885
8144
1.10
1.90
3.3
2.8
3.32
3.38
e6/l
0.06
409
3771
67
481
1.40
1.89
1.0
1.0
—
—
—
0
0
38
243
1.57
1.89
1.8
1.8
—
—
—
0
0
126
994
1.27
1.88
3.3
3.0
34.95
35.02
umol/l
0.01
115
934
148
1191
1.25
1.87
1.6
1.6
484.79
369.87
mu/l
1.47
123
959
6
17
3.53
1.83
1.0
1.0
—
—
—
0
0
38
245
1.55
1.83
1.6
1.4
68.44
92.72
nmol/24h
2.08
38
245
59
417
1.42
1.83
2.4
1.6
25.54
22.49
umol/l
0.32
54
386
611
6738
0.90
1.82
1.5
1.6
962.48
998.52
mu/l
0.52
527
5766
71
520
1.37
1.80
5.9
5.1
7.36
7.25
mmol/l
0.07
64
438
18
94
1.92
1.79
2.3
3.4
10.85
22.97
mg/l
—
8
24
22
123
1.79
1.79
2.7
2.3
—
—
—
0
0
582
5262
1.12
1.77
2.4
2.5
33.51
47.69
u/l
0.89
496
4481
6
18
3.34
1.74
1.2
2.7
—
—
—
0
0
42
282
1.49
1.71
2.5
3.0
182.82
163.20
umol/l
0.12
22
147
11
48
2.29
1.70
2.5
1.5
22.96
33.57
nmol/l
0.27
11
48
331
3773
0.87
1.70
1.5
1.5
59.40
61.40
ug/l
0.37
290
3200
558
5046
1.12
1.70
2.4
2.4
5751.77
6414.54
u/l
0.15
194
2037
14
68
2.06
1.70
1.9
1.5
20.86
12.86
nmol/l
—
7
14
1034
9635
1.09
1.70
1.8
1.7
—
—
—
0
0
43
291
1.48
1.69
1.3
1.4
125.56
130.80
nmol/l
0.38
43
291
27
164
1.65
1.67
2.1
1.5
—
—
—
0
0
7
163
0.43
1.65
1.4
1.5
—
—
—
0
0
124
995
1.25
1.65
3.7
3.1
24.97
24.35
mg/l
0.08
83
661
251
2157
1.17
1.64
6.8
4.2
—
—
—
0
0
2725
26302
1.06
1.64
2.8
2.7
—
—
estimate
—
0
0
201
1696
1.19
1.63
3.9
3.7
330.38
410.37
mg/l
0.50
98
807
41
277
1.48
1.63
1.3
1.4
156.71
160.86
mmol/24h
0.12
41
277
173
1444
1.20
1.59
1.1
1.1
6.22
5.74
u/ml
0.10
79
663
58
421
1.38
1.58
1.6
1.9
1.89
2.84
u/ml
0.43
11
135
70
525
1.34
1.56
1.2
1.3
0.97
2.15
u/ml
1.00
43
278
149
1233
1.21
1.51
1.3
1.2
—
—
—
0
0
45
317
1.42
1.47
3.1
2.8
193.47
345.99
e6/l
0.54
45
310
130
1065
1.23
1.47
2.2
2.5
0.93
0.84
nmol/l
0.61
108
920
423
3803
1.12
1.46
2.7
2.3
0.30
0.36
e6/l
0.34
398
3585
273
3113
0.87
1.45
1.1
1.1
0.66
0.63
ratio
0.34
30
315
74
567
1.31
1.45
1.0
1.1
0.09
2.24
u/ml
1.19
17
144
47
335
1.41
1.45
1.7
1.7
1.75
3.32
nmol/l
1.11
40
258
57
420
1.36
1.45
2.2
1.5
11.25
7.02
ug/l
0.31
51
377
782
7255
1.09
1.44
3.0
3.0
4.45
4.45
e9/l
0.00
692
6477
5
16
3.13
1.44
1.2
1.1
—
—
—
0
0
206
1766
1.17
1.43
1.1
1.1
0.84
1.22
u/ml
0.45
90
797
32
212
1.51
1.42
1.3
1.3
—
—
—
0
0
41
286
1.44
1.42
1.3
1.2
—
—
—
0
0
28
180
1.56
1.42
1.1
1.3
0.72
3.89
u/ml
0.59
28
180
682
6295
1.09
1.42
3.4
2.9
7.01
6.99
umol/l
0.01
592
5450
65
491
1.33
1.41
2.4
2.1
0.19
0.50
mmol/l
0.27
57
466
37
254
1.46
1.40
1.1
1.1
0.34
6.70
u/ml
1.39
18
156
205
1763
1.17
1.38
1.2
1.3
93.16
135.23
titre
0.59
19
174
504
5522
0.91
1.37
4.4
4.1
31.50
31.88
%
0.35
356
3992
9
41
2.20
1.36
1.2
1.7
307.22
307.93
umol/24h
—
9
41
19
112
1.70
1.35
3.3
1.5
—
—
—
0
0
386
3472
1.12
1.34
3.2
2.9
—
—
—
0
0
153
1287
1.19
1.34
1.1
1.1
0.30
0.37
u/ml
0.14
49
392
199
1717
1.16
1.30
1.4
1.5
0.43
0.44
nmol/l
0.07
154
1358
192
1652
1.17
1.30
1.1
1.1
—
—
—
0
0
1924
18488
1.06
1.30
2.2
2.2
—
—
—
0
0
41
292
1.41
1.30
2.3
2.8
27.14
191.76
ug/l
0.93
36
271
1854
17800
1.06
1.29
2.4
2.3
—
—
—
0
0
18
106
1.70
1.29
1.1
1.1
—
—
—
0
0
239
2094
1.15
1.27
1.1
1.1
1.59
2.17
u/ml
0.78
129
1112
65
500
1.30
1.27
3.2
2.6
2.05
1.49
g/24h
0.50
42
303
40
286
1.40
1.25
2.3
2.5
599.39
613.25
ml
0.08
23
208
191
1650
1.16
1.24
1.1
1.1
—
—
—
0
0
218
1902
1.15
1.24
1.2
1.1
—
—
—
0
0
16
265
0.60
1.22
5.8
6.4
9.13
8.64
%
0.11
16
265
16
265
0.60
1.22
2.9
3.2
37.56
45.55
%
0.80
16
265
510
4682
1.10
1.22
2.9
2.5
0.22
0.22
g/l
0.37
481
4398
211
1840
1.15
1.22
1.1
1.1
4.95
6.28
u/ml
0.55
114
1028
320
3564
0.89
1.21
1.5
1.5
1.15
1.15
ratio
0.01
196
2167
324
2912
1.12
1.18
1.1
1.1
—
—
—
0
0
335
3022
1.11
1.15
1.6
1.8
0.23
0.29
mg/l
1.62
116
1406
15
87
1.73
1.15
1.1
1.1
0.16
0.96
u/ml
—
9
48
316
3507
0.90
1.14
1.5
1.5
—
—
—
0
0
32
224
1.43
1.14
1.1
1.1
—
—
—
0
0
32
224
1.43
1.14
1.1
1.1
—
3.90
—
0
21
28
191
1.47
1.13
1.1
1.2
2.40
9.74
%
—
5
19
12
65
1.85
1.13
1.2
1.2
—
—
—
0
0
14
80
1.75
1.12
2.6
3.1
3.29
5.42
ug/l
1.87
14
80
26
175
1.49
1.12
2.9
2.7
218.61
105.68
ng/l
0.41
19
111
20
127
1.58
1.11
1.5
2.7
—
—
—
0
0
31
217
1.43
1.11
6.2
6.0
80.70
67.64
mg/l
0.28
20
159
612
5694
1.08
1.10
2.9
2.8
0.66
0.70
ug/l
0.67
360
3158
87
710
1.23
1.09
1.6
1.7
—
—
—
0
0
18
112
1.61
1.08
1.4
1.4
40.50
37.07
%
0.20
12
75
20
303
0.66
1.07
1.6
1.6
—
—
—
0
0
204
1795
1.14
1.07
1.4
1.3
4.01
3.72
ug/l
0.19
188
1656
13
74
1.76
1.06
5.5
2.4
15.18
4.46
%
—
6
19
16
253
0.63
1.04
1.7
2.4
—
—
—
0
0
356
3244
1.10
1.03
2.4
2.9
117.39
45.75
u/ml
0.41
348
3145
17
106
1.61
1.02
1.0
1.0
1.74
0.47
u/ml
—
10
51
9
47
1.92
1.02
1.4
1.1
—
—
—
0
0
136
1167
1.17
1.01
1.3
1.4
—
—
—
0
0
1575
15156
1.05
1.00
1.8
1.8
—
—
—
0
0
755
8009
0.94
0.99
1.3
1.3
—
—
—
0
0
739
6956
1.07
0.99
1.3
1.2
—
—
—
0
0
39
291
1.34
0.99
2.7
2.6
151.00
144.85
nmol/l
0.13
32
260
5
23
2.17
0.98
1.0
1.0
0.01
0.03
u/ml
—
5
16
222
2485
0.89
0.97
1.5
1.6
57.64
59.97
ug/l
0.36
222
2485
30
412
0.73
0.97
1.0
1.1
—
—
—
0
0
94
785
1.20
0.96
1.3
1.3
0.14
0.31
nmol/l
—
9
28
196
1735
1.13
0.96
1.2
1.3
1048.00
1067.76
titre
—
5
49
176
1549
1.14
0.95
1.1
1.1
5.41
4.26
u/ml
0.12
88
789
188
1662
1.14
0.95
1.6
1.3
265.85
246.31
u/ml
0.37
118
1034
65
524
1.24
0.94
1.7
1.5
1.07
1.31
promille
0.60
52
408
100
845
1.19
0.92
1.2
1.2
13.00
22.70
u/ml
—
5
38
146
1272
1.15
0.92
1.3
1.2
—
—
—
0
0
198
1764
1.13
0.89
7.6
4.3
24.51
24.66
mmol/l
0.40
186
1667
199
1774
1.13
0.89
1.1
1.1
1.55
1.92
u/ml
0.29
95
924
50
394
1.27
0.89
1.3
1.6
35.47
37.02
%
0.09
30
238
8
43
1.86
0.87
1.8
1.2
14.85
16.53
umol/l
—
8
36
378
3489
1.09
0.87
1.9
2.0
—
—
—
0
0
265
2915
0.91
0.86
1.5
1.5
—
—
—
0
0
136
1185
1.15
0.86
2.2
2.4
—
—
—
0
0
16
240
0.67
0.85
1.0
1.1
—
—
—
0
0
15
228
0.66
0.85
1.7
2.5
—
—
—
0
0
271
2970
0.91
0.83
1.6
1.6
—
—
—
0
0
36
275
1.31
0.82
1.3
1.4
—
—
—
0
0
52
417
1.25
0.81
1.2
1.4
168.73
198.15
pmol/l
0.57
52
417
55
444
1.24
0.81
1.1
1.1
1631.40
1456.74
miu/ml
0.61
55
444
16
105
1.53
0.81
1.6
2.5
—
—
—
0
0
37
284
1.30
0.81
2.1
1.7
1.10
1.33
nmol/l
0.80
32
210
14
89
1.57
0.81
2.9
1.6
—
—
—
0
0
31
232
1.34
0.80
2.2
2.5
504.53
501.21
min
0.05
17
180
105
904
1.16
0.80
2.9
2.8
1.34
1.45
mmol/l
0.91
100
873
126
1100
1.15
0.80
1.8
1.7
8561.02
12569.48
e6/l
0.62
100
781
17
114
1.49
0.79
1.0
1.0
0.02
1.51
u/ml
—
10
54
0
24
0.00
0.79
0.0
1.0
—
0.15
—
0
9
62
510
1.22
0.78
1.4
1.7
52.69
53.01
%
0.02
36
319
45
357
1.26
0.78
5.8
7.5
8.68
71.44
ug/l
0.76
31
240
261
2854
0.91
0.78
1.5
1.5
1.23
1.25
mm
0.52
204
2112
134
1178
1.14
0.78
1.1
1.2
—
—
—
0
0
47
376
1.25
0.76
2.4
2.3
105.38
105.54
mmol/l
0.09
47
370
47
376
1.25
0.76
2.4
2.3
3.97
3.98
mmol/l
0.07
47
370
469
5002
0.93
0.76
1.9
2.0
0.06
0.03
estimate
0.37
100
1183
17
115
1.48
0.76
1.0
1.0
0.09
4.30
u/ml
—
9
51
0
28
0.00
0.76
0.0
1.0
—
0.12
—
0
13
82
697
1.18
0.74
3.6
3.4
0.95
1.52
%
1.35
75
632
66
551
1.20
0.73
1.2
1.2
—
—
—
0
0
146
1298
1.13
0.73
1.1
1.1
—
—
—
0
0
5
25
2.00
0.72
1.0
1.0
—
—
—
0
0
93
1076
0.86
0.72
1.1
1.2
—
—
—
0
0
366
3407
1.08
0.72
1.3
1.3
262.73
235.05
miu/ml
0.73
173
1679
80
681
1.18
0.72
1.6
2.0
—
—
—
0
0
20
142
1.41
0.72
1.1
1.1
—
—
—
0
0
44
353
1.25
0.71
1.8
1.5
4.51
6.58
u/l
2.64
35
308
84
978
0.86
0.71
1.4
1.5
6.96
6.87
mmol/l
0.13
75
887
7
41
1.71
0.70
1.0
1.2
—
—
—
0
0
27
354
0.76
0.69
2.7
3.2
—
—
—
0
0
29
221
1.31
0.69
2.8
1.8
—
—
—
0
0
225
2056
1.10
0.69
2.8
2.9
—
—
—
0
0
9
59
1.53
0.68
7.6
10.7
8.47
5.60
mmol/l
—
9
59
45
365
1.23
0.67
2.5
2.3
1.20
1.20
mmol/l
0.16
45
359
675
6434
1.05
0.66
1.6
1.5
—
—
—
0
0
29
223
1.30
0.66
1.1
1.1
—
4.17
—
0
12
13
86
1.51
0.66
1.2
1.3
23.25
64.44
ng/l
—
8
52
60
506
1.19
0.62
1.3
1.2
—
—
—
0
0
42
342
1.23
0.62
1.6
2.2
—
—
—
0
0
51
608
0.84
0.60
1.8
1.8
67.24
1596.14
pmol/l
—
7
77
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
23
174
1.32
0.59
2.5
2.6
0.61
0.61
mmol/l
0.01
23
174
7
113
0.62
0.58
1.0
1.1
—
—
—
0
0
31
387
0.80
0.57
1.2
1.2
9.45
9.01
mm/h
0.13
31
387
24
184
1.31
0.57
1.0
1.1
42.60
35.26
iu/ml
0.18
24
184
228
2111
1.08
0.56
1.5
1.3
—
—
—
0
0
17
228
0.74
0.54
1.6
1.5
0.00
0.03
estimate
0.80
17
228
10
147
0.68
0.53
1.4
1.1
—
—
—
0
0
6
39
1.54
0.53
1.5
1.3
0.18
0.17
umol/l
—
6
39
13
181
0.72
0.52
1.1
1.2
—
—
—
0
0
65
563
1.16
0.52
1.1
1.1
12.13
8.18
iu/ml
0.44
20
160
53
452
1.17
0.51
1.2
1.1
1.07
1.05
ratio
0.45
42
375
75
658
1.14
0.51
1.3
1.3
0.17
0.20
nmol/l
0.54
60
509
97
866
1.12
0.51
4.0
3.8
—
—
—
0
0
75
852
0.88
0.50
4.9
3.9
19.33
28.29
u/ml
1.93
75
828
94
838
1.12
0.50
1.1
1.1
1.49
1.46
g/l
0.33
87
761
422
4439
0.95
0.50
1.5
1.5
—
—
—
0
0
26
207
1.26
0.49
1.0
1.2
7.38
6.39
u/ml
0.08
17
143
37
307
1.21
0.49
1.5
1.4
—
—
—
0
0
15
110
1.36
0.48
1.2
1.2
7.12
8.02
pmol/l
—
7
42
713
6873
1.04
0.48
1.6
1.6
3.38
3.45
mmol/l
0.87
454
4546
170
1569
1.09
0.47
2.7
2.4
6.89
5.67
umol/l
0.51
130
1165
36
431
0.83
0.47
2.0
1.7
6.21
6.14
mmol/l
0.08
28
333
120
1092
1.10
0.46
1.1
1.1
3.63
3.57
eliau/ml
0.01
63
563
56
486
1.15
0.46
1.2
1.4
1.72
1.45
nmol/l
0.62
48
433
24
192
1.25
0.44
1.1
1.1
—
—
—
0
0
24
194
1.24
0.41
1.0
1.0
—
—
—
0
0
23
185
1.24
0.41
1.1
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
0.02
—
0
6
188
2008
0.93
0.40
1.3
1.3
—
—
—
0
0
8
61
1.31
0.39
1.1
1.3
—
—
—
0
0
60
531
1.13
0.39
1.1
1.1
—
—
—
0
0
7
106
0.66
0.39
1.4
1.5
61.00
57.84
%
—
7
88
14
106
1.32
0.39
1.1
1.2
29.51
38.70
g/l
—
8
59
41
353
1.16
0.39
3.7
3.9
9.00
9.26
mg/l
0.11
35
287
43
372
1.16
0.38
3.0
2.9
25.52
70.34
mg/l
1.04
27
270
9
67
1.34
0.38
1.0
1.0
—
—
—
0
0
34
398
0.85
0.37
3.9
2.8
—
—
—
0
0
28
234
1.20
0.37
1.1
1.1
49.89
169.15
ng/l
—
9
54
5
37
1.35
0.37
1.0
1.1
—
—
—
0
0
56
496
1.13
0.37
1.3
1.2
115.45
230.00
titre
1.81
11
92
6
43
1.40
0.35
1.3
1.0
—
—
—
0
0
41
357
1.15
0.35
1.2
1.4
74.51
73.78
umol/l
0.07
41
357
48
543
0.88
0.34
1.3
1.1
—
—
—
0
0
54
604
0.89
0.33
1.2
1.1
23.40
16.81
u/ml
0.43
24
256
6
90
0.67
0.32
1.2
1.3
6.17
5.55
mmol/l
—
6
90
27
229
1.18
0.32
2.7
2.3
8.00
8.10
mmol/l
0.05
27
229
39
444
0.88
0.32
3.2
2.5
33.84
25.46
mg/l
0.58
31
316
40
351
1.14
0.31
1.2
1.2
—
—
—
0
0
25
211
1.19
0.31
2.1
2.4
17.23
16.51
%
0.49
25
211
1241
12179
1.02
0.31
1.8
1.9
—
—
—
0
0
129
1377
0.94
0.30
1.9
1.9
—
—
—
0
0
16
129
1.24
0.30
1.1
1.3
—
—
—
0
0
407
4212
0.96
0.29
1.8
1.7
—
—
—
0
0
55
496
1.11
0.29
1.3
1.2
—
142.00
—
0
15
26
222
1.17
0.29
1.3
1.5
1.00
3.34
%
—
6
41
63
573
1.10
0.29
1.1
1.1
—
—
—
0
0
165
1563
1.06
0.28
6.5
8.3
—
—
—
0
0
41
459
0.89
0.27
1.3
1.3
—
—
—
0
0
79
730
1.08
0.27
2.5
3.3
208.43
51.44
u/ml
0.35
79
719
18
150
1.20
0.26
1.1
1.2
—
—
—
0
0
18
150
1.20
0.26
1.8
1.6
10.70
8.66
ug/l
0.93
18
150
5
73
0.68
0.26
1.0
1.1
0.04
0.03
u/ml
—
5
73
57
520
1.10
0.25
1.1
1.0
—
—
—
0
0
25
216
1.16
0.25
1.0
1.3
27.80
28.49
s
0.26
25
216
9
73
1.23
0.25
2.4
3.9
—
—
—
0
0
52
473
1.10
0.25
3.0
3.3
0.77
0.80
nmol/l
0.22
37
375
268
2580
1.04
0.25
2.0
2.0
0.02
0.03
estimate
0.07
86
937
226
2355
0.96
0.24
1.9
1.8
—
—
—
0
0
10
78
1.28
0.24
3.8
2.8
2.58
3.27
mg/l
—
10
78
6
85
0.71
0.24
1.0
1.5
34.00
28.70
%
—
6
78
40
360
1.11
0.23
2.7
1.8
6.20
3.47
mg/l
1.20
40
347
36
401
0.90
0.23
1.3
1.3
1120.00
1057.53
titre
—
5
73
5
38
1.32
0.23
1.4
1.8
29.10
20.35
pmol/l
—
5
32
79
737
1.07
0.22
1.4
1.3
—
—
—
0
0
43
390
1.10
0.22
1.0
1.0
—
—
—
0
0
35
314
1.12
0.22
1.0
1.0
9.45
13.50
u/ml
0.42
21
213
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
2880.60
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
15
126
1.19
0.21
1.1
1.1
13.83
6.00
u/ml
0.99
15
126
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
6.8
—
69.00
—
0
5
10
123
0.81
0.20
1.0
1.1
—
—
—
0
0
134
1404
0.95
0.20
1.4
1.4
24.70
22.81
u/l
0.22
107
1175
82
771
1.06
0.20
2.4
2.2
—
—
—
0
0
45
490
0.92
0.20
1.4
1.2
—
—
—
0
0
222
2299
0.96
0.20
3.1
2.9
1.02
1.02
ratio
0.80
200
2025
23
260
0.88
0.19
1.2
1.2
67.57
67.82
ug/l
0.01
23
260
77
724
1.06
0.19
1.5
1.5
33.14
36.98
nmol/l
0.45
69
659
44
405
1.09
0.18
1.6
2.1
18.15
22.71
ug/l
1.22
44
396
139
1450
0.96
0.18
3.1
3.8
107.79
1199.24
u/ml
0.94
121
1246
10
82
1.22
0.17
1.5
1.5
—
20.50
—
0
8
312
3042
1.03
0.16
2.1
2.2
8.45
7.22
ug/l
0.43
279
2716
8
68
1.18
0.16
1.1
1.1
—
—
—
0
0
34
311
1.09
0.16
1.4
1.5
17244.27
80578.75
e6/l
1.47
15
172
467
4580
1.02
0.16
2.2
2.2
—
—
—
0
0
40
432
0.93
0.16
1.2
1.2
—
—
—
0
0
6
77
0.78
0.15
1.0
1.1
2.83
3.40
kpa
—
6
68
6
80
0.75
0.15
1.0
1.1
—
—
—
0
0
6
80
0.75
0.15
1.0
1.1
8.13
7.48
kpa
—
6
71
9
78
1.15
0.15
3.1
3.4
2118.33
2514.32
u/l
—
9
72
113
1084
1.04
0.15
4.1
4.0
3.83
3.85
mmol/l
0.19
113
1073
9
80
1.13
0.15
1.7
2.1
—
—
—
0
0
415
4069
1.02
0.15
1.5
1.4
—
—
—
0
0
7
88
0.80
0.14
1.4
1.6
5.86
2.74
%
—
7
77
1924
19383
0.99
0.14
1.6
1.7
—
—
—
0
0
14
160
0.87
0.14
1.1
1.8
40.87
40.86
g/l
0.00
14
160
41
382
1.07
0.14
1.3
1.4
67273.37
75216.38
e6/l
0.07
30
263
109
1049
1.04
0.13
1.1
1.1
61.35
10454.96
iu/ml
0.64
24
258
1357
13451
1.01
0.13
2.4
2.2
—
—
—
0
0
458
4507
1.02
0.12
2.4
2.3
6.29
6.16
ph
2.45
296
2819
14
158
0.89
0.12
2.2
1.8
—
—
—
0
0
47
444
1.06
0.11
2.9
3.2
54.69
56.12
%
0.16
42
386
54
513
1.05
0.11
2.6
2.0
15.10
22.37
mg/l
1.25
18
189
389
3953
0.98
0.11
3.8
4.4
39.45
28.26
ug/l
0.16
270
3059
20
182
1.10
0.11
1.2
1.2
—
—
—
0
0
43
455
0.94
0.11
4.1
3.8
—
—
—
0
0
72
750
0.96
0.10
1.2
1.3
81.05
27.11
u/l
0.62
62
657
28
260
1.08
0.10
1.7
2.8
0.84
1.28
ug/l
1.25
28
242
501
4947
1.01
0.10
2.2
2.1
—
—
—
0
0
408
4137
0.99
0.10
4.1
3.8
7.36
7.35
ph
0.70
288
2990
29
310
0.94
0.10
1.5
1.5
—
—
—
0
0
39
369
1.06
0.09
1.4
1.4
1936.96
2596.03
e6/l
0.33
24
252
68
654
1.04
0.09
2.1
1.9
—
—
—
0
0
50
477
1.05
0.09
2.9
2.8
—
—
—
0
0
23
248
0.93
0.09
1.5
1.6
1.00
3.64
u/field
1.85
18
184
13
145
0.90
0.09
1.2
1.4
7.37
7.40
ph
—
7
100
11
97
1.13
0.09
1.5
1.4
—
—
—
0
0
504
4984
1.01
0.08
2.2
2.1
—
—
—
0
0
305
3095
0.98
0.08
1.5
1.3
—
—
—
0
0
5
64
0.78
0.08
1.0
1.1
—
—
—
0
0
7
64
1.09
0.08
1.0
1.4
—
0.24
—
0
18
13
117
1.11
0.08
1.3
1.3
60.48
50.99
%
0.48
13
103
487
4922
0.99
0.08
2.1
2.1
—
—
—
0
0
17
156
1.09
0.08
3.4
2.2
24046.58
821.51
e6/l
0.46
12
114
6
72
0.83
0.07
1.0
2.5
—
—
—
0
0
18
167
1.08
0.06
1.2
1.2
—
—
—
0
0
255
2519
1.01
0.06
1.5
1.4
—
—
—
0
0
501
4970
1.01
0.06
2.1
2.0
—
—
—
0
0
12
131
0.92
0.05
3.9
2.1
51929.29
18297.52
e6/l
—
7
73
140
1422
0.98
0.05
1.4
1.3
—
—
—
0
0
32
307
1.04
0.05
1.1
1.1
—
—
—
0
0
18
191
0.94
0.04
1.7
2.0
8.67
120.02
ug/min
—
6
43
66
645
1.02
0.04
4.3
4.9
169.51
57.04
u/ml
0.71
22
208
895
8913
1.00
0.04
1.9
1.8
3.38
3.46
ratio
1.05
640
6545
35
338
1.04
0.04
1.9
1.9
1.10
1.68
u/field
0.65
20
194
41
398
1.03
0.04
1.4
1.5
33.50
33.78
g/l
0.05
35
363
51
498
1.02
0.03
1.2
1.2
—
—
—
0
0
42
431
0.97
0.03
1.7
1.5
—
—
—
0
0
48
488
0.98
0.01
3.3
3.0
—
—
—
0
0
13
136
0.96
0.00
2.4
2.1
—
—
—
0
0
50
494
1.01
0.00
1.3
1.4
—
—
—
0
0
52
514
1.01
0.00
1.5
1.5
0.48
0.51
e9/l
0.40
52
514
54
538
1.00
0.00
1.2
1.2
—
—
—
0
0
78
785
0.99
0.00
2.9
3.8
317.89
765.63
u/ml
0.59
70
726
24
237
1.01
0.00
1.1
1.1
—
—
—
0
0
22
221
1.00
0.00
1.3
1.1
—
—
—
0
0
136
1359
1.00
0.00
1.1
1.1
21.46
16.51
au/ml
0.21
40
375
7
78
0.90
0.00
1.7
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
0.02
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
-0.00
1.0
1.1
—
24.21
—
0
16
9
94
0.96
-0.00
1.0
1.2
63.56
65.41
ug/l
—
9
94
0
5
0.00
-0.00
0.0
1.0
—
0.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
-0.00
1.2
1.1
108.80
87.32
titre
—
5
59
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
79
0.89
-0.00
1.6
1.2
137.86
138.60
mmol/l
—
7
65
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
78.40
—
0
5
0
8
0.00
-0.00
0.0
3.0
—
—
—
0
0
5
54
0.93
-0.00
2.6
3.4
40.20
44.10
umol/l
—
5
44
6
61
0.98
-0.00
1.0
1.2
—
—
—
0
0
6
69
0.87
-0.00
1.3
1.1
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—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_MYOPIA and mortality.

Females

Parameter HR [95% CI] p-value
H7_MYOPIA 1.275 [1.12, 1.45] < 0.001
Birth year 0.995 [0.99, 1.0] 0.238

During the follow-up period (1.1.1998 — 31.12.2019), 930 out of 21450 females with H7_MYOPIA died.

Males

Parameter HR [95% CI] p-value
H7_MYOPIA 1.268 [1.08, 1.49] 0.004
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 715 out of 15335 males with H7_MYOPIA died.

Mortality risk

Mortality risk for people of age

years, who have H7_MYOPIA.

N-year risk Females Males
1 0.094% 0.216%
5 0.567% 1.516%
10 1.732% 3.595%
15 3.437% 6.607%
20 6.059% 11.048%

Relationships between endpoints

Index endpoint: H7_MYOPIA – Myopia

GWS hits: 13

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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