Postpartum haemorrhage due to retained placenta

O15_POSTPART_HAEMORRH_PLACENTA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O72.0
  • Hospital discharge: ICD-9 6660
  • Cause of death: ICD-10 O72.0
  • Cause of death: ICD-9 6660

2 out of 7 registries used, show all original rules.

6334

4. Check minimum number of events

None

6334

5. Include endpoints

None

6334

6. Filter based on genotype QC (FinnGen only)

5784

Control definitions (FinnGen only)

Control exclude
!(NUMBER_OF_OFFSPRING>0), !(O15_DELIVERY, O15_DELIVERY_PROXY)

Extra metadata

First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 37145 37145 -
Only index persons 36716 36716 -
Unadjusted period prevalence (%)
Whole population 1.06 1.06 -
Only index persons 1.35 1.35 -
Median age at first event (years)
Whole population - 30.09 -
Only index persons - 30.08 -

-FinnGen-

Key figures

All Female Male
Number of individuals 5784 5784 -
Unadjusted period prevalence (%) 2.05 2.05 -
Median age at first event (years) 30.69 30.69 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
6021
Matched controls
60210
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8832
FHL
Manual placenta removal and associated scraping
28.2
307.7
361
136
6660A
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM STADII III]
+∞
307.7
1117
*
MBA04
NOMESCO Finland
Curettage of uterus after delivery
12.1
307.7
352
308
6660C
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC PARTIALI]
+∞
307.7
488
*
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
30.3
307.7
1434
615
6660B
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC TOTALI]
+∞
307.7
453
*
O72.0
ICD-10 Finland
Third-stage haemorrhage
16384.0
307.7
4033
*
8831
FHL
Uterine exploration and / or scraping or suction emptying (ad 24 hours)
22.2
307.7
260
122
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
4.3
258.7
745
1931
8841
FHL
Uterine emptying and scraping (ad 6 weeks)
21.3
245.0
184
89
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
3.6
158.0
571
1716
WW500
NOMESCO Finland
Blood transfusion
4.9
151.8
345
734
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
3.5
135.4
511
1575
O80.8
ICD-10 Finland
Other single spontaneous delivery
2.4
125.7
1047
4900
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
5.2
115.2
243
484
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
3.5
107.3
389
1165
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
2.6
95.6
614
2530
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
4.7
77.9
181
391
MBC20
NOMESCO Finland
Repair of obstetric laceration of vulva
5.0
75.0
162
329
MBB10
NOMESCO Finland
Packing of delivered uterus
14.3
67.3
61
43
MBC00
NOMESCO Finland
Repair of obstetric laceration of cervix uteri
9.7
61.9
72
75
O71.3
ICD-10 Finland
Obstetric laceration of cervix
9.1
59.0
72
80
ZXD05
NOMESCO Finland
Urgent procedure
1.5
48.7
2087
15550
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
2.3
38.2
297
1323
WX600
NOMESCO Finland
Single shot through catheter
2.4
36.1
251
1065
MAX99
NOMESCO Finland
Assistance to normal delivery
1.5
31.2
1486
11098
O70.0
ICD-10 Finland
First degree perineal laceration during delivery
2.6
30.7
176
682
6653B
ICD-9 Finland
Other obstetrical trauma, Laceration of cervix
9.3
29.1
35
38
6671A
ICD-9 Finland
Retained placenta or membranes, without haemorrhage, Retained portions of placenta or membranes, without haemorrhage
4.4
27.3
69
160
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
1.8
24.5
380
2170
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
0.6
24.2
395
6523
8502
FHL
Evacuation and abrasion
1.8
24.0
346
1933
O61.8
ICD-10 Finland
Other failed induction of labour
3.3
23.9
90
276
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.6
23.4
131
502
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
1.9
22.8
304
1655
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
2.0
22.8
254
1302
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
0.7
22.8
826
11424
W92
ICPC
Compl labour/ delivery livebirth
1.7
22.6
390
2297
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.3
22.1
2249
18758
PC7NT
NOMESCO Finland
Endovascular occlusion of uteral arteries to stop puerperal bleeding
9.0
21.2
26
29
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
3.1
20.5
83
267
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.3
19.3
2191
18447
2800A
ICD-9 Finland
Iron deficiency anaemias, Secondary to blood loss (chronic)
7.5
19.1
27
36
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
1.3
18.8
2391
20413
O81.4
ICD-10 Finland
Vacuum extractor delivery
1.4
18.4
824
6023
SPAT1197
SPAT
Extensive health check-up of expecting family
1.3
17.9
2028
17030
8834
FHL
Kerviksrupure repair
13.1
17.4
30
23
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
1.8
17.2
244
1356
W85
ICPC
Gestational diabetes
1.4
16.8
684
4907
MAE00
NOMESCO Finland
Outlet vacuum delivery
1.4
16.6
693
4993
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
1.6
16.6
401
2577
O48
ICD-10 Finland
Prolonged pregnancy
1.5
16.2
509
3467
SPAT1379
SPAT
Health check-up of pregnant person
1.3
16.0
1827
15306
W78
ICPC
Pregnancy
1.3
15.9
2489
21647
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
1.4
15.1
909
6963
B01AB05
ATC
enoxaparin; parenteral
1.3
15.0
1336
10829
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
1.9
14.7
191
1033
Z39.1
ICD-10 Finland
Care and examination of lactating mother
1.6
14.1
337
2159
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.3
14.0
1236
9991
8839
FHL
Other measure in this category
17.6
13.8
21
12
SPAT1373
SPAT
Combined screening in early pregnancy
1.7
13.8
269
1639
O82.0
ICD-10 Finland
Delivery by elective caesarean section
0.6
13.7
279
4392
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
2.0
13.5
149
765
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.3
13.4
1412
11666
8801
FHL
Suction cup delivery
1.9
13.4
171
922
SPAT1380
SPAT
Postpartum check-up
1.3
13.3
1534
12807
MBB96
NOMESCO Finland
Other manual procedure on delivered uterus
21.2
13.3
19
9
N81.1
ICD-10 Finland
Cystocele
1.6
13.2
301
1909
8833
FHL
Correction of II ^ 0 or III ^ 0 perineumrupth or vaginal rupture
3.5
13.1
43
122
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
0.7
13.0
422
6021
6670A
ICD-9 Finland
Retained placenta or membranes, without haemorrhage, Retained placenta without haemorrhage
3.4
12.8
45
133
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.5
12.8
484
3419
O85
ICD-10 Finland
Puerperal sepsis
2.1
12.8
123
601
6482A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Anaemia
4.2
12.7
33
79
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
1.7
12.6
230
1379
LFE20
NOMESCO Finland
Suture of perineum
4.3
12.4
31
72
H01CC01
ATC
ganirelix; parenteral
1.6
12.2
295
1898
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
1.5
12.1
364
2456
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
2.1
12.0
116
568
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
1.8
11.8
167
931
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
1.6
11.7
239
1475
ZXE00
NOMESCO Finland
One hour or less
1.2
11.6
2145
18790
OAA10, ,
SPAT
1.3
11.5
789
6150
W90
ICPC
Uncompl labour/delivery livebirth
1.3
11.4
804
6287
MBA10
NOMESCO Finland
Manual exploration of delivered uterus
11.8
11.3
20
17
MBC33
NOMESCO Finland
Repair of complete rupture of perineum
2.2
11.1
95
444
6611B
ICD-9 Finland
Abnormality of forces of labour, Secondary uterine inertia
2.2
11.1
95
444
6748X
ICD-9 Finland
Other and unspecified complications of the puerperium, not elsewhere classified, Other
3.6
10.8
34
94
OAA11, ,
SPAT
1.3
10.7
1061
8674
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1.4
10.5
468
3406
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
2.3
10.3
78
348
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.2
10.2
2033
17888
6400A
ICD-9 Finland
Haemorrhage in early pregnancy, Threatened abortion
2.2
10.2
84
388
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.3
10.1
1134
9398
N81.6
ICD-10 Finland
Rectocele
1.5
10.1
346
2402
G02AB01
ATC
methylergometrine; systemic
2.6
9.9
55
212
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.2
9.7
1426
12159
6641B
ICD-9 Finland
Trauma to perineum and vulva during delivery, Second-degree perineal laceration
4.2
9.6
25
60
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
9.6
2625
23730
O20.0
ICD-10 Finland
Threatened abortion
1.5
9.4
276
1856
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
1.2
9.3
1236
10423
O99.80
ICD-10 Finland
The fear of childbirth
1.3
9.1
721
5726
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.2
9.1
1177
9903
MBW96
NOMESCO Finland
Other operation after delivery or abortion
3.4
9.0
31
91
OAA12, ,
SPAT
1.3
8.9
797
6427
G03GA05
ATC
follitropin alfa; parenteral
1.4
8.9
338
2394
ULC02
NOMESCO Finland
Hysteroscopy
1.4
8.8
326
2296
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
8.7
1097
9194
6661A
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ATONICA UTERI]
2.8
8.6
41
147
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
1.9
8.5
105
562
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
1.4
8.5
350
2512
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
1.4
8.5
329
2336
MAC96
NOMESCO Finland
Other induction or advancement of labour
1.5
8.5
286
1979
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
1.9
8.5
98
514
N39.3
ICD-10 Finland
Stress incontinence
1.4
8.2
420
3130
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
1.9
8.2
101
542
6654B
ICD-9 Finland
Other obstetrical trauma, High vaginal laceration
3.2
8.1
31
98
Z10.8
ICD-10 Finland
Routine general health check-up of other defined subpopulations
1.5
8.0
272
1885
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.2
7.9
3208
29753
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
1.5
7.8
247
1689
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
2.1
7.8
73
356
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
1.7
7.8
149
909
TLW12
NOMESCO Finland
Insertion of frozen embryo
1.6
7.8
172
1088
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
0.5
7.6
62
1260
ZXD00
NOMESCO Finland
Emergency procedure
1.6
7.6
177
1134
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
1.6
7.6
172
1095
LCA10
NOMESCO Finland
Curettage of body of uterus
1.6
7.2
153
959
O02.1
ICD-10 Finland
Missed abortion
1.3
7.2
588
4684
G03GA01
ATC
chorionic gonadotrophin; parenteral
1.4
7.1
366
2733
MBA05
NOMESCO Finland
Curettage of uterus after abortion
1.7
7.1
119
702
6700A
ICD-9 Finland
Major puerperal infection
2.2
7.0
55
250
6310A
ICD-9 Finland
Other abnormal product of conception[OVUM ABORTIVUM]
1.7
7.0
119
703
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
1.3
7.0
427
3268
TPH07
NOMESCO Finland
Cathetrisation of artery
1.4
6.9
261
1848
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.2
6.8
948
8012
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.2
6.8
908
7649
TMA00
NOMESCO Finland
Episiotomy
1.3
6.7
378
2865
WX892
NOMESCO Finland
Monitored bed care
1.5
6.6
194
1308
Z3232
NOMESCO Finland
Midwife
1.2
6.6
997
8492
2851A
ICD-9 Finland
Other and unspecified anaemias, Acute posthaemorrhagic anaemia
12.2
6.6
11
9
LX2A3, ,
SPAT
0.7
6.6
175
2592
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
0.4
6.5
41
909
W17
ICPC
Post-partum bleeding
2.7
6.4
32
118
O90.8
ICD-10 Finland
Other complications of the puerperium, not elsewhere classified
2.8
6.4
30
107
T89
ICPC
Diabetes insulin dependent
0.5
6.4
57
1120
N85.6
ICD-10 Finland
Intrauterine synechiae
3.7
6.4
19
51
6535B
ICD-9 Finland
Disproportion, Unusually large foetus causing disproportion[EPÄTAVALLISEN ISO SIKIÖ (YLI 4500 G), SYNN AIKANA]
2.5
6.3
37
148
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
1.4
6.1
303
2248
O43.2
ICD-10 Finland
Morbidly adherent placenta
7.7
6.1
13
17
O47.9
ICD-10 Finland
False labour, unspecified
1.4
6.1
232
1648
6320A
ICD-9 Finland
Missed abortion[ABORTUS INHIBITUS (""""MISSED ABORTION"""")]
1.8
6.1
83
462
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
1.8
6.0
82
456

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
521
1825
3.03
111.05
1.7
2.3
3.52
3.74
g/l
4.25
492
1731
874
5666
1.63
35.89
1.7
2.0
28.43
28.72
s
0.87
837
5483
1022
7796
1.37
17.66
1.5
1.5
—
—
—
0
0
1083
8396
1.35
16.80
1.5
1.5
64.90
62.17
ug/l
0.94
948
7132
1025
7895
1.36
16.56
1.5
1.5
1.21
1.16
ratio
0.97
724
4757
2537
22372
1.23
13.50
2.0
1.9
—
—
—
0
0
341
2229
1.56
13.13
1.7
1.8
20.20
20.03
s
0.31
294
1842
2265
19818
1.23
12.76
2.0
1.9
—
—
—
0
0
1792
15313
1.24
12.55
1.6
1.6
1132.76
1004.33
mu/l
4.92
1580
13205
2257
19828
1.22
12.01
1.9
1.9
—
—
—
0
0
3325
30474
1.20
11.01
3.0
2.7
—
—
estimate
—
0
0
64
256
2.52
10.70
1.2
1.2
—
—
—
0
0
619
4711
1.35
10.55
3.2
3.5
32.94
32.52
%
0.45
498
3716
1691
14579
1.22
10.50
1.9
1.9
—
—
—
0
0
236
1504
1.59
10.19
1.7
1.5
538.66
349.60
mu/l
2.13
200
1228
296
1985
1.52
10.19
1.8
1.9
81.95
97.48
%
17.79
286
1903
1210
10133
1.24
9.80
1.6
1.5
—
—
—
0
0
457
3384
1.38
9.27
2.4
3.1
7.36
7.35
ph
0.17
324
2463
2670
24237
1.18
9.11
2.3
2.0
—
—
—
0
0
2627
23867
1.18
8.74
2.2
2.2
—
—
—
0
0
37
131
2.84
7.93
1.0
1.0
—
—
—
0
0
1885
16772
1.18
7.82
5.4
5.5
1.05
1.05
inr
0.02
1531
13898
4715
48887
0.84
7.22
13.3
13.5
332.61
332.27
g/l
2.16
4680
48646
1266
14385
0.85
6.18
3.4
3.4
0.13
0.36
—
8
89
5771
56948
1.32
4.47
10.8
10.1
—
—
—
0
0
2512
23493
1.12
4.35
1.9
1.9
—
—
—
0
0
134
929
1.45
4.13
3.0
3.3
21.47
22.11
mg/l
0.09
91
611
419
3439
1.23
4.04
2.4
2.3
5.23
4.80
umol/l
0.63
268
2539
118
807
1.47
3.92
3.5
3.2
—
—
—
0
0
94
1410
0.66
3.89
1.2
1.2
257.92
248.26
u/ml
0.10
62
972
1290
11675
1.13
3.80
3.1
3.2
98.28
99.42
%
1.18
1248
11333
814
7169
1.16
3.57
1.2
1.2
—
—
—
0
0
284
3512
0.80
3.37
1.1
1.1
0.96
6.95
u/ml
—
5
42
1903
17726
1.11
3.32
4.2
4.8
1.21
1.22
mmol/l
5.86
1776
16707
5535
54560
1.18
3.05
10.6
10.9
18.28
18.29
mg/l
0.01
4588
44521
1340
14557
0.90
3.03
3.2
3.4
1.02
1.23
kg/l
0.80
902
9523
3068
29350
1.09
2.95
3.8
4.0
6.02
6.14
mmol/l
3.38
2601
26083
896
8057
1.13
2.90
2.6
2.4
8666.65
7502.07
u/l
0.49
511
3842
4065
39419
1.10
2.82
4.3
4.2
899.76
2035.42
e6/l
1.65
49
426
1445
13406
1.10
2.65
1.8
1.7
1.40
0.84
mg/l
6.37
1148
10219
12
45
2.67
2.45
1.3
1.4
—
—
—
0
0
265
2200
1.21
2.41
1.3
1.3
21.62
25.24
u/l
1.14
222
1809
5967
59398
1.51
2.40
17.7
17.2
131.50
133.11
g/l
24.31
5946
59188
605
5376
1.14
2.38
3.2
3.2
—
—
—
0
0
5966
59388
1.50
2.38
17.6
17.2
7.01
6.75
e9/l
13.34
5913
58691
166
1317
1.27
2.30
2.9
2.7
30.88
29.16
iu/ml
—
5
57
85
1164
0.73
2.27
4.0
4.5
1.26
1.16
mmol/l
0.87
74
1042
5965
59385
1.48
2.27
17.6
17.1
4.41
4.46
e12/l
18.87
5913
58711
335
2861
1.18
2.25
1.3
1.3
3.26
3.77
ug/l
1.27
311
2684
321
2733
1.18
2.24
1.9
1.9
0.03
0.03
estimate
0.02
112
1116
5963
59364
1.47
2.24
17.6
17.1
260.08
267.58
e9/l
19.94
5917
58760
5964
59377
1.47
2.22
17.5
17.0
90.15
90.16
fl
0.03
5941
59166
5964
59379
1.46
2.20
17.5
17.0
30.06
30.04
pg
0.40
5942
59170
5964
59385
1.45
2.13
17.8
17.3
39.33
40.28
%
6.60
5941
59146
332
2851
1.17
2.11
1.2
1.2
10.96
11.74
u/l
0.55
295
2408
20
102
1.96
2.10
1.5
2.1
15.86
16.52
%
0.41
20
102
23
124
1.86
2.06
1.0
1.2
—
—
—
0
0
69
490
1.41
2.05
1.6
1.6
5.31
5.62
mmol/l
0.85
64
424
241
2863
0.84
2.03
1.2
1.2
—
—
—
0
0
394
4498
0.87
2.03
3.5
4.7
1.03
1.04
mmol/l
0.81
370
4200
2370
24743
0.93
2.02
2.4
2.4
75.40
3547.57
nmol/l
0.50
2260
23609
780
7131
1.11
1.92
2.1
2.3
295.41
371.66
ng/l
0.58
609
5727
1123
12047
0.92
1.90
3.1
3.4
7.39
7.40
ph
1.06
789
8437
66
909
0.72
1.89
1.5
1.6
4878.53
7511.07
e6/l
1.09
47
654
15
291
0.51
1.85
1.8
1.5
120.07
126.12
nmol/l
0.31
15
291
1443
13590
1.08
1.84
2.1
2.1
2.56
2.50
mg/l
0.55
1238
11940
2136
20411
1.07
1.84
4.7
5.3
1.21
1.22
mmol/l
10.40
1862
17853
45
659
0.68
1.83
1.4
1.4
—
—
—
0
0
369
4194
0.87
1.81
1.7
1.9
—
—
—
0
0
49
704
0.69
1.80
1.7
1.8
42.48
53.69
mu/l
0.30
42
652
702
7667
0.90
1.75
2.4
2.3
2.41
2.41
mmol/l
0.34
635
6847
110
1392
0.79
1.74
1.5
1.4
7489.77
1155.61
e6/l
0.57
90
1112
1210
12886
0.92
1.72
1.3
1.3
6.91
7.63
u/ml
0.22
541
5748
1803
18908
0.93
1.68
2.7
2.7
0.05
0.05
0.06
22
222
279
2419
1.16
1.64
1.4
1.5
0.45
0.50
nmol/l
0.39
236
1918
352
3975
0.88
1.60
1.3
1.4
—
—
—
0
0
109
1363
0.80
1.59
1.4
1.3
32.70
21.48
e6/l
0.38
87
1024
1824
19076
0.94
1.55
4.0
4.2
37.40
37.26
g/l
0.61
1722
18120
110
878
1.26
1.55
2.2
2.2
—
—
—
0
0
236
2735
0.86
1.55
2.3
3.1
57.95
72.34
ng/l
6.39
213
2488
956
10222
0.92
1.51
2.2
2.3
7.81
8.65
e6/l
0.79
847
9144
1535
16124
0.94
1.49
2.3
2.4
67.81
58.55
u/l
0.27
1436
15215
5
129
0.39
1.48
1.2
1.1
—
280.00
—
0
8
256
2934
0.87
1.46
2.3
2.1
8.73
6.60
iu/ml
0.46
67
736
47
335
1.41
1.45
1.3
1.7
282.88
282.17
mosm/kgh2o
0.11
42
277
109
878
1.25
1.44
1.4
1.3
—
—
—
0
0
607
5569
1.10
1.44
1.3
1.4
—
—
—
0
0
12
59
2.04
1.43
1.1
1.2
32.67
35.46
s
—
7
46
536
4892
1.11
1.42
1.8
2.0
—
—
—
0
0
1855
19340
0.94
1.41
3.2
3.4
74.96
64.77
e6/l
0.30
1181
12293
42
587
0.71
1.39
1.3
1.2
0.16
0.16
nmol/l
0.01
30
417
1477
15495
0.94
1.37
3.0
3.0
2.35
2.35
mmol/l
0.16
1385
14550
3661
35796
1.06
1.37
3.5
3.4
64.12
63.98
ug/l
0.03
3483
34406
646
6987
0.92
1.35
2.7
2.7
382.21
270.18
ng/l
0.30
348
3194
25
159
1.57
1.34
1.0
1.0
0.96
1.73
u/ml
0.32
14
101
0
39
0.00
1.33
0.0
1.3
—
0.18
—
0
12
81
637
1.28
1.33
1.1
1.2
—
—
—
0
0
51
684
0.74
1.32
5.1
6.0
11.35
11.06
mmol/l
0.35
46
614
51
684
0.74
1.32
5.1
6.0
106.50
105.73
mmol/l
0.65
46
614
26
168
1.55
1.31
1.1
1.1
—
—
—
0
0
381
4212
0.90
1.26
2.2
2.0
—
—
—
0
0
383
4232
0.90
1.25
2.2
2.0
—
—
—
0
0
80
634
1.27
1.25
1.2
1.1
11.83
17.03
u/ml
1.35
34
310
1292
12289
1.07
1.24
2.3
2.3
—
0.80
—
0
25
2426
25022
0.95
1.23
5.3
5.2
9.63
9.40
umol/l
0.73
2297
23739
58
443
1.31
1.21
1.6
1.8
32.57
23.65
mg/l
0.52
21
177
383
4221
0.90
1.20
2.1
1.9
—
—
—
0
0
267
3002
0.88
1.19
1.4
1.3
3.52
0.80
u/ml
0.74
16
232
36
255
1.41
1.19
1.1
1.1
—
—
—
0
0
1333
13965
0.94
1.18
1.4
1.4
22.69
24.03
iu/ml
0.20
386
4273
78
624
1.25
1.15
1.3
1.3
73.87
68.24
ug/l
0.44
78
624
5
20
2.50
1.15
1.8
1.2
—
—
—
0
0
580
6247
0.92
1.13
1.6
1.6
—
—
—
0
0
286
3189
0.89
1.13
1.1
1.1
0.57
0.60
ratio
0.35
25
310
137
1164
1.18
1.12
1.1
1.2
—
—
—
0
0
140
1193
1.18
1.11
1.3
1.2
—
—
—
0
0
20
305
0.65
1.10
2.3
2.5
36.94
70.93
mg/l
0.49
14
213
5
21
2.38
1.09
1.2
1.9
—
—
—
0
0
12
66
1.82
1.08
1.2
1.2
—
—
—
0
0
71
567
1.26
1.08
1.0
1.1
—
—
—
0
0
58
738
0.78
1.07
2.3
2.7
0.93
0.87
nmol/l
0.26
53
630
107
897
1.20
1.04
2.0
2.0
134.74
131.07
g/l
1.39
84
727
2011
19465
1.05
1.03
2.8
2.8
0.01
0.08
estimate
0.92
673
6058
118
1389
0.85
1.03
1.2
1.2
3.50
3.54
mmol/l
0.23
109
1328
44
577
0.76
1.03
2.5
2.6
77.21
91.73
ug/min
0.08
27
380
183
2081
0.88
1.01
1.2
1.3
—
—
—
0
0
799
8464
0.94
1.01
2.3
2.5
519.77
521.76
mosm/kgh2o
0.08
683
7398
304
3349
0.90
0.99
1.1
1.1
0.86
0.87
g/l
0.33
304
3342
24
164
1.47
0.99
1.3
1.1
3.40
3.75
iu/ml
—
5
8
50
388
1.29
0.97
1.7
1.5
0.49
0.49
e9/l
0.03
50
388
47
605
0.78
0.97
1.7
1.4
—
—
—
0
0
9
50
1.80
0.96
1.3
1.5
—
—
—
0
0
1080
10306
1.06
0.95
1.5
1.6
—
—
—
0
0
829
7849
1.07
0.95
1.3
1.3
25.71
26.37
iu/l
0.25
746
6900
2494
24302
1.04
0.95
8.8
8.8
0.00
0.00
e9/l
0.13
2119
20140
288
2613
1.11
0.93
1.6
1.7
—
—
—
0
0
2695
26322
1.04
0.91
2.5
2.4
—
—
—
0
0
3699
37599
0.96
0.90
6.8
6.9
72.75
72.39
u/l
0.23
3522
35965
50
631
0.79
0.90
1.1
1.0
0.24
0.39
u/ml
—
7
131
29
210
1.38
0.90
1.1
1.1
25.26
27.86
iu/ml
0.12
29
210
8
42
1.91
0.88
1.0
1.1
8.82
11.54
pmol/l
—
8
42
116
997
1.17
0.88
1.8
2.4
24.27
24.62
mmol/l
1.10
110
931
43
551
0.78
0.88
1.5
1.5
—
—
—
0
0
43
551
0.78
0.88
1.5
1.5
—
—
—
0
0
43
551
0.78
0.88
1.5
1.5
—
—
—
0
0
43
551
0.78
0.88
1.5
1.5
—
—
—
0
0
53
422
1.26
0.87
1.2
1.2
11.17
16.96
u/ml
—
6
52
48
605
0.79
0.86
1.2
1.2
—
—
nmol/l
—
0
0
2505
25653
0.96
0.86
3.0
3.1
6.27
6.25
ph
0.69
1506
14922
123
1416
0.87
0.85
1.2
1.3
138.84
153.89
au/ml
0.72
32
354
1018
10637
0.95
0.84
3.7
3.9
11.28
10.36
mg/mmol
0.28
597
6544
76
909
0.83
0.84
1.7
2.0
1.04
1.61
ug/l
0.39
70
821
425
3951
1.08
0.83
1.1
1.1
120.42
230.43
titre
0.89
12
117
29
388
0.75
0.82
2.4
2.8
0.74
1.35
g/24h
1.90
17
221
334
3622
0.92
0.82
1.1
1.1
—
—
—
0
0
11
65
1.69
0.82
1.1
1.2
—
—
—
0
0
19
130
1.46
0.80
1.6
1.9
6.38
7.62
mmol/l
1.39
19
130
4585
46339
0.96
0.80
4.1
4.3
36.44
36.69
mmol/mol
1.82
4415
44696
53
653
0.81
0.80
3.2
3.3
22.96
40.03
mg/l
1.91
45
561
0
24
0.00
0.79
0.0
1.2
—
33.73
—
0
24
162
1819
0.89
0.79
5.4
6.1
22.97
24.15
mmol/l
5.22
157
1735
0
26
0.00
0.78
0.0
1.3
—
0.38
—
0
20
135
1187
1.14
0.78
2.9
3.2
57.07
57.75
%
0.31
135
1187
77
648
1.19
0.77
1.1
1.1
3.36
7.24
iu/ml
3.72
27
204
0
27
0.00
0.77
0.0
1.0
—
0.08
—
0
17
0
27
0.00
0.77
0.0
1.1
—
—
—
0
0
53
650
0.81
0.77
3.1
3.3
19.15
26.48
mg/l
2.68
45
559
583
5508
1.06
0.75
2.0
1.9
0.04
0.04
estimate
0.02
125
1339
30
227
1.32
0.74
3.7
2.2
1.51
1.47
nmol/l
0.06
25
189
1440
14873
0.96
0.74
2.7
2.8
40.38
68.12
e6/l
0.98
1050
10964
546
5152
1.07
0.73
3.8
3.6
4.63
4.57
pmol/l
0.44
499
4748
5202
52385
0.95
0.72
5.8
5.8
1.61
1.66
mu/l
3.01
5011
50640
711
6768
1.06
0.72
1.2
1.2
—
—
—
0
0
92
793
1.16
0.71
1.4
1.3
980.00
1001.44
titre
—
10
139
104
1192
0.87
0.71
1.2
1.2
836.48
1323.63
pmol/l
—
10
98
14
206
0.68
0.71
2.7
2.0
—
—
—
0
0
323
3474
0.93
0.68
2.0
2.1
0.15
0.26
e6/l
1.92
297
3237
422
4494
0.93
0.68
1.2
1.2
—
—
—
0
0
80
930
0.86
0.67
2.2
1.9
144.51
235.50
ug/l
1.19
73
821
2663
27138
0.97
0.67
5.1
5.6
0.04
0.04
e9/l
0.88
2415
24097
27
205
1.32
0.67
2.7
2.8
—
—
—
0
0
18
249
0.72
0.66
2.2
2.7
48.55
45.71
%
0.75
11
154
115
1016
1.13
0.65
2.2
2.1
—
—
—
0
0
71
830
0.85
0.65
2.2
1.8
10.23
10.14
g/l
0.05
62
782
1278
13191
0.96
0.64
3.1
3.2
7.28
7.69
mmol/l
2.77
1150
11753
1534
14912
1.04
0.64
2.3
2.4
15.41
26.52
ng/l
0.87
598
5761
205
1875
1.10
0.63
2.0
2.5
7.42
7.42
ph
0.67
171
1549
221
2401
0.92
0.62
4.3
6.6
6.35
6.56
mmol/l
0.28
214
2323
12
176
0.68
0.61
20.9
17.7
913.67
1308.76
nmol/l
1.20
12
166
111
1250
0.89
0.61
1.3
1.3
317.33
319.54
ug/g
0.03
57
633
21
279
0.75
0.61
1.2
1.3
128.45
143.84
mmol/24h
0.75
21
279
14
96
1.46
0.61
1.0
1.0
0.05
0.12
u/ml
—
6
45
158
1430
1.11
0.61
2.5
2.1
0.99
1.27
g/l
5.30
137
1262
1228
12670
0.96
0.61
2.6
2.7
0.22
0.27
e6/l
0.58
857
8918
360
3835
0.93
0.61
2.2
2.1
—
—
—
0
0
13
187
0.69
0.60
1.1
1.0
5.00
7.09
u/ml
0.34
13
187
76
657
1.16
0.60
1.8
1.9
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
255.48
—
0
21
0
21
0.00
0.60
0.0
1.0
—
4.13
—
0
21
42
510
0.82
0.60
1.1
1.1
—
—
—
0
0
1373
14129
0.96
0.60
1.4
1.4
2.11
2.09
g/l
0.32
930
9535
17
122
1.39
0.60
1.0
1.1
—
—
—
0
0
19
255
0.74
0.59
1.1
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
0.22
—
0
14
0
22
0.00
0.59
0.0
2.0
—
2.96
—
0
17
8
53
1.51
0.58
1.3
1.2
112.00
88.75
titre
—
8
53
8
53
1.51
0.58
2.6
2.5
—
—
—
0
0
47
562
0.84
0.58
3.2
3.1
1.29
2.23
ratio
1.55
30
307
25
193
1.30
0.57
2.0
2.4
31.60
29.58
%
0.33
25
193
619
5917
1.05
0.57
1.6
1.5
66.66
60.19
ug/l
2.47
619
5917
25
320
0.78
0.57
1.1
2.7
400.76
615.83
u/ml
1.81
25
315
164
1797
0.91
0.57
1.8
2.2
54.84
68.33
ng/l
0.62
148
1606
46
383
1.20
0.56
1.0
1.0
—
—
—
0
0
162
1477
1.10
0.56
2.5
2.9
247.29
384.68
mg/l
1.16
62
646
148
1628
0.91
0.56
1.5
1.6
6.45
6.48
mmol/l
0.07
138
1484
40
329
1.22
0.55
1.1
1.1
7.54
11.77
u/ml
—
7
67
5
90
0.56
0.55
1.0
1.2
—
—
—
0
0
25
318
0.79
0.55
1.0
1.1
—
—
—
0
0
201
2176
0.92
0.54
1.9
1.9
—
—
—
0
0
9
60
1.50
0.54
1.3
1.1
20.73
20.56
mmol/l
—
9
51
35
285
1.23
0.54
2.5
3.0
133.57
266.57
e6/l
0.73
35
279
2668
27112
0.97
0.53
5.1
5.6
0.51
0.51
e9/l
0.07
2422
24109
34
276
1.23
0.53
1.2
1.4
—
—
—
0
0
39
470
0.83
0.53
3.1
3.6
5.96
6.84
mmol/l
1.23
32
370
6
39
1.54
0.53
1.0
1.1
1.85
1.47
umol/24h
—
6
39
133
1206
1.11
0.52
1.3
1.2
2.66
3.99
u/ml
1.89
56
527
4866
48993
0.96
0.52
3.7
3.7
5.49
5.52
mmol/l
1.54
4643
46911
146
1331
1.10
0.52
1.1
1.1
—
—
—
0
0
554
5791
0.95
0.52
1.2
1.2
—
—
—
0
0
1017
10491
0.96
0.51
3.1
3.4
66.15
62.07
mg/l
0.20
598
6452
146
1597
0.91
0.50
1.2
1.1
—
—
—
0
0
226
2104
1.08
0.50
1.2
1.2
—
—
—
0
0
1680
17172
0.97
0.50
1.4
1.4
1.24
1.54
u/ml
0.77
557
5406
536
5130
1.05
0.49
2.3
2.3
6.24
6.23
ph
0.10
325
3200
127
1154
1.10
0.49
1.0
1.1
118.27
118.92
%
0.12
115
1059
80
708
1.13
0.49
2.4
2.5
—
—
—
0
0
7
45
1.56
0.48
1.0
1.1
—
—
—
0
0
7
46
1.52
0.48
1.4
1.2
8.89
4.13
kpa
—
7
40
142
1550
0.91
0.48
1.3
1.3
525.50
445.02
mg/l
0.69
137
1495
84
747
1.13
0.48
1.1
1.1
1.44
1.45
g/l
0.10
74
708
2774
28137
0.97
0.48
5.1
5.7
0.18
0.18
e9/l
0.11
2545
25440
28
344
0.81
0.47
1.2
1.3
—
—
—
0
0
1835
18717
0.97
0.47
2.7
3.0
30.37
28.69
u/l
0.44
1745
17937
583
5598
1.05
0.47
1.6
1.7
—
—
—
0
0
40
336
1.19
0.47
1.1
1.1
0.22
4.43
nmol/l
—
10
47
33
398
0.83
0.47
2.2
1.6
1.54
1.17
promille
0.70
25
309
38
318
1.20
0.47
1.1
1.4
—
—
—
0
0
5181
51534
1.04
0.46
9.1
9.8
139.52
139.63
mmol/l
3.45
5073
50554
40
473
0.84
0.46
1.2
1.2
11.38
9.89
mm/h
0.28
40
473
58
504
1.15
0.46
2.0
2.5
1299.31
1402.93
e6/l
0.48
49
432
13
94
1.38
0.46
1.0
1.0
0.49
0.37
u/ml
—
5
39
559
5819
0.96
0.45
2.3
2.3
5.92
6.04
umol/l
0.07
463
4963
23
287
0.80
0.45
2.0
1.7
3328.00
3292.73
titre
—
5
44
167
1803
0.92
0.45
1.4
1.3
51.43
39.77
u/ml
—
10
174
7
50
1.40
0.45
1.6
1.1
—
—
—
0
0
35
417
0.84
0.45
1.2
1.4
9.79
9.47
umol/l
0.21
35
397
953
9808
0.97
0.44
1.4
1.4
605.49
535.60
titre
0.47
182
2033
27
220
1.23
0.43
1.1
1.1
—
—
—
0
0
133
1446
0.92
0.43
1.2
1.2
—
—
—
0
0
162
1745
0.93
0.42
3.1
2.7
—
—
—
0
0
331
3481
0.95
0.42
2.3
2.2
0.23
0.23
g/l
0.22
315
3309
89
985
0.90
0.42
1.4
1.5
0.66
0.61
g/l
0.28
68
774
28
338
0.83
0.42
1.5
1.2
42.71
74.70
%
—
7
33
1697
16649
1.03
0.41
2.3
2.3
—
—
—
0
0
1176
12046
0.97
0.41
1.9
1.9
126.74
129.73
u/l
0.07
1140
11552
5
33
1.52
0.41
1.4
1.3
1.28
1.74
mg/l
—
5
26
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
501
5211
0.96
0.41
1.6
1.7
1189.87
1186.54
nmol/l
0.03
383
4277
212
1990
1.07
0.41
1.4
1.4
51.11
81.14
pmol/l
2.85
205
1939
0
17
0.00
0.40
0.0
1.0
—
0.15
—
0
10
154
1658
0.93
0.40
2.1
2.0
—
—
—
0
0
38
324
1.17
0.40
1.8
2.3
31.92
32.18
pg
0.12
38
324
253
2392
1.06
0.39
2.7
2.6
1.02
1.02
ratio
0.41
222
2070
7
102
0.69
0.39
2.3
1.7
—
—
—
0
0
56
634
0.88
0.39
1.2
1.4
—
—
—
0
0
13
171
0.76
0.39
1.3
1.5
39.89
36.98
g/l
0.52
13
160
14
182
0.77
0.39
1.2
1.3
—
0.23
—
0
9
193
2057
0.94
0.39
2.2
2.1
1.17
1.19
g/l
0.33
182
1979
95
1042
0.91
0.38
1.2
1.2
11.65
11186.23
iu/ml
0.64
29
240
46
527
0.87
0.38
1.2
1.2
0.61
0.66
ratio
0.27
25
311
60
675
0.89
0.38
1.1
1.0
1.56
0.90
u/ml
0.24
15
150
207
1947
1.07
0.38
2.0
2.5
5.03
5.07
kpa
0.45
200
1868
137
1477
0.93
0.38
1.3
1.3
—
—
—
0
0
61
542
1.13
0.38
4.2
3.5
47.84
543.86
u/ml
0.86
55
501
2054
20858
0.98
0.38
1.7
1.8
1.31
1.31
mmol/l
0.01
1781
18539
17
214
0.79
0.37
1.2
1.1
—
—
—
0
0
40
462
0.86
0.37
2.1
2.4
27.90
23.32
mg/l
0.36
29
319
727
7055
1.03
0.37
1.3
1.3
139.04
149.02
u/ml
0.29
272
2936
33
280
1.18
0.37
2.5
2.4
—
—
—
0
0
2753
27854
0.98
0.36
5.1
5.6
2.01
1.98
e9/l
0.36
2545
25365
186
1748
1.07
0.36
9.0
9.0
94.76
94.57
%
0.14
186
1743
94
1027
0.91
0.36
3.5
3.5
109.02
261.81
u/ml
0.54
81
863
1506
15339
0.98
0.36
4.7
4.9
—
—
—
0
0
12
157
0.76
0.35
1.6
1.8
7.42
8.79
ug/l
1.02
12
157
668
6481
1.03
0.35
1.6
1.5
1.23
1.26
mm
0.67
496
4863
14
179
0.78
0.35
1.1
1.2
—
72.38
—
0
21
4718
47438
0.97
0.35
5.0
5.0
14.19
14.21
pmol/l
0.24
4496
45480
1266
12406
1.03
0.35
2.1
2.1
292.63
293.13
umol/l
0.08
1166
11420
5168
51896
0.97
0.34
4.1
4.2
2.88
2.90
mmol/l
1.02
4980
50164
611
5924
1.03
0.34
1.9
2.2
23.83
24.44
%
0.59
559
5507
530
5126
1.04
0.34
1.3
1.3
127.53
155.53
u/ml
0.72
495
4804
30
351
0.85
0.34
1.3
1.3
66.50
67.94
umol/l
0.11
30
351
20
163
1.23
0.34
1.0
1.4
—
—
—
0
0
5183
51616
1.03
0.33
9.2
9.9
3.88
3.89
mmol/l
0.75
5058
50521
178
1888
0.94
0.33
1.8
1.8
9.89
4.76
ug/l
0.57
158
1672
340
3261
1.05
0.33
7.0
7.0
4.87
4.98
kpa
1.87
330
3144
340
3261
1.05
0.33
7.0
7.0
14.77
14.05
kpa
1.20
329
3142
6
46
1.30
0.33
1.3
1.1
—
—
—
0
0
6
87
0.69
0.33
1.0
1.0
0.01
0.07
u/ml
—
6
87
1213
12372
0.98
0.33
2.6
2.6
0.00
60.95
estimate
—
6
22
38
331
1.15
0.33
1.1
1.1
9.08
8.83
u/ml
0.03
22
224
65
587
1.11
0.32
1.2
1.2
—
—
—
0
0
20
242
0.83
0.32
1.2
1.5
161.90
82.03
nmol/24h
0.44
20
242
188
1989
0.94
0.32
2.2
2.1
0.23
0.23
g/l
0.16
178
1908
18
146
1.23
0.32
1.0
1.4
—
—
—
0
0
185
1748
1.06
0.32
9.0
8.9
1.21
1.38
%
1.47
185
1738
166
1564
1.06
0.31
6.8
6.9
—
—
—
0
0
33
380
0.87
0.31
1.1
1.2
—
68.00
—
0
5
55
611
0.90
0.31
1.2
1.2
—
—
—
0
0
58
642
0.90
0.30
1.2
1.4
6.68
6.54
g/l
0.18
42
461
262
2504
1.05
0.30
7.5
7.6
—
—
—
0
0
10
75
1.33
0.30
1.0
1.1
—
—
—
0
0
58
641
0.90
0.30
1.2
1.4
3.01
3.04
g/l
0.05
44
457
58
641
0.90
0.30
1.2
1.4
0.39
0.37
g/l
0.20
44
458
13
102
1.28
0.30
1.2
2.4
43.13
41.89
g/l
0.69
13
102
119
1273
0.93
0.30
1.5
1.6
6.12
6.81
mmol/l
4.30
119
1252
2505
25319
0.98
0.29
3.2
3.2
0.04
0.15
estimate
0.69
694
6038
119
1272
0.93
0.29
1.4
1.3
—
—
—
0
0
60
544
1.10
0.29
1.1
1.1
1500.33
1477.45
miu/ml
0.07
60
544
685
6678
1.03
0.29
1.6
1.6
—
—
—
0
0
340
3276
1.04
0.28
7.0
7.1
7.40
7.42
ph
2.63
165
1810
1816
18404
0.98
0.28
1.7
1.8
103.22
99.65
pmol/l
2.65
1012
10228
12
151
0.79
0.28
1.3
1.5
—
—
—
0
0
221
2311
0.95
0.27
1.5
1.6
0.22
0.27
mg/l
0.62
72
933
31
271
1.14
0.27
2.2
2.5
340.98
141.98
au/ml
—
5
53
422
4353
0.97
0.26
1.3
1.3
33.71
41.40
au/ml
0.52
21
266
278
2673
1.04
0.26
1.7
1.7
7.91
11.39
u/ml
1.02
82
779
48
531
0.90
0.26
1.3
1.2
127.29
120.74
pmol/l
0.44
48
531
214
2237
0.96
0.26
1.1
1.1
12.64
5.45
eliau/ml
0.37
26
386
171
1626
1.05
0.26
1.3
1.2
656.00
1070.31
titre
—
5
65
120
1129
1.06
0.26
1.4
1.3
1.26
1.25
nmol/l
0.02
110
971
5
74
0.68
0.26
1.2
1.9
—
—
—
0
0
141
1334
1.06
0.25
1.4
1.5
33.88
36.24
nmol/l
0.40
125
1245
38
425
0.89
0.25
1.3
1.6
48.42
45.27
%
0.19
24
243
31
273
1.14
0.25
1.6
1.5
0.10
0.01
estimate
0.41
31
273
454
4670
0.97
0.25
1.3
1.3
—
—
—
0
0
32
361
0.89
0.24
2.4
2.6
—
—
—
0
0
178
1865
0.95
0.24
2.1
2.1
—
—
—
0
0
6
83
0.72
0.24
1.7
1.3
56.83
61.88
ug/l
—
6
83
3255
32780
0.98
0.24
3.4
3.5
0.00
3.32
estimate
4.07
792
7167
615
6010
1.03
0.24
1.3
1.4
—
—
—
0
0
296
3061
0.97
0.23
3.0
2.7
—
—
—
0
0
84
898
0.93
0.23
3.2
3.5
1.50
1.38
mmol/l
0.48
84
886
1602
16217
0.98
0.22
5.4
5.8
—
4.42
—
0
9
7
94
0.74
0.22
1.3
1.3
—
—
—
0
0
44
400
1.10
0.22
2.3
2.5
200.46
219.68
e6/l
0.27
35
331
704
6902
1.02
0.21
2.4
2.5
5.03
4.93
e6/l
0.04
348
3172
20
231
0.87
0.21
1.5
1.6
71.11
84.85
ng/l
0.94
20
231
5
42
1.19
0.21
1.0
1.6
65.40
56.83
%
—
5
36
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
0.13
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
320
3104
1.03
0.21
2.6
3.1
1.23
1.23
mmol/l
0.32
276
2711
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
214
2221
0.96
0.21
1.5
1.3
52.91
31.37
u/ml
0.33
12
146
0
13
0.00
0.21
0.0
4.5
—
949.62
—
0
8
0
13
0.00
0.21
0.0
9.1
—
109.23
—
0
13
34
306
1.11
0.20
2.2
2.6
15.55
14.63
index
0.15
20
182
17
198
0.86
0.20
1.3
1.2
28.12
27.36
s
0.40
17
198
19
219
0.87
0.20
2.5
2.0
2109.74
1956.33
ml
0.43
19
207
0
14
0.00
0.20
0.0
1.0
—
507.86
—
0
14
672
6593
1.02
0.20
1.6
1.5
—
—
—
0
0
691
6783
1.02
0.20
1.8
2.1
2.57
2.51
g/l
2.25
630
6281
12
99
1.21
0.19
1.1
1.2
—
—
—
0
0
21
239
0.88
0.19
2.6
2.0
322.17
188.91
umol/l
0.41
12
117
6
53
1.13
0.18
2.2
1.8
—
—
—
0
0
144
1502
0.96
0.18
1.2
1.3
—
—
—
0
0
44
405
1.09
0.18
7.5
6.8
23.41
68.63
ug/l
0.51
31
261
1766
17493
1.01
0.18
3.4
3.5
0.00
0.00
estimate
2.86
771
6954
15
128
1.17
0.18
1.3
1.5
—
—
—
0
0
34
309
1.10
0.18
2.2
1.8
1.57
2.24
u/field
0.39
14
171
984
9704
1.02
0.18
3.0
3.3
—
—
—
0
0
454
4640
0.98
0.18
2.4
2.3
20.49
20.33
au/ml
0.02
53
693
84
794
1.06
0.18
1.5
1.3
—
—
—
0
0
116
1107
1.05
0.18
2.3
2.3
1.60
1.48
index
0.10
63
576
63
590
1.07
0.18
1.1
1.2
1.62
1.37
u/ml
0.14
34
319
64
682
0.94
0.17
2.2
2.7
2.18
2.10
mmol/l
0.08
34
399
51
474
1.08
0.17
1.0
1.1
303.96
298.79
mg/l
0.14
44
449
475
4849
0.98
0.17
1.5
1.5
340.90
281.50
mu/l
0.49
423
4329
972
9589
1.02
0.17
2.6
2.5
118.55
96.01
ug/g
1.39
777
7609
5139
51513
0.98
0.17
3.9
3.9
1.54
1.55
mmol/l
1.27
4958
49853
5
70
0.71
0.16
5.2
2.1
26.20
30.55
mg/mmol
—
5
64
2995
30119
0.99
0.16
7.1
7.7
3.88
3.93
e9/l
0.69
2671
26564
4880
48931
0.99
0.16
12.8
12.9
13.33
13.28
%
2.71
4831
48414
132
1373
0.96
0.16
1.9
2.2
8.97
10.46
mg/l
2.00
125
1299
42
389
1.08
0.16
1.3
1.4
29.32
24.08
umol/l
0.48
37
363
23
256
0.90
0.16
1.3
1.6
2.08
2.77
u/field
0.22
13
175
11
130
0.85
0.16
1.4
1.5
—
—
—
0
0
144
1494
0.96
0.15
2.1
2.6
0.64
0.63
%
0.11
144
1487
220
2262
0.97
0.15
2.1
2.2
67.87
67.53
g/l
0.27
202
2128
449
4407
1.02
0.15
2.3
2.5
27.71
30.58
u/ml
0.47
434
4270
421
4130
1.02
0.14
2.4
2.6
10.48
10.49
g/l
0.02
380
3855
78
742
1.05
0.14
4.6
4.5
144.11
77.34
u/ml
0.44
34
274
209
2149
0.97
0.14
1.1
1.1
1.28
2.12
u/ml
1.59
94
1113
2548
25627
0.99
0.14
5.1
5.6
30.36
30.13
%
0.61
2451
24511
328
3351
0.98
0.14
1.1
1.1
—
—
—
0
0
20
179
1.12
0.14
1.1
1.1
—
—
—
0
0
76
724
1.05
0.14
3.0
2.9
—
—
—
0
0
466
4581
1.02
0.13
2.2
2.3
35.05
34.82
u/l
0.02
379
3899
2449
24630
0.99
0.13
5.1
5.7
2.74
2.80
%
0.86
2330
23280
5158
51679
0.99
0.13
3.9
4.0
4.81
4.85
mmol/l
2.17
4987
50124
275
2811
0.98
0.13
2.3
3.0
7.38
7.38
ph
0.32
134
1512
12
138
0.87
0.13
1.5
1.6
—
—
—
0
0
4056
40433
1.01
0.12
2.9
2.9
32.32
32.10
u/l
0.07
3909
39115
49
462
1.06
0.12
1.6
1.6
1.19
2.85
u/ml
—
7
113
159
1544
1.03
0.12
1.0
1.1
5.12
4.33
u/ml
0.22
58
671
252
2464
1.02
0.12
2.2
2.3
3.51
6.63
iu/l
0.60
118
1153
744
7529
0.99
0.12
2.4
2.4
0.74
1.06
e6/l
2.38
387
3812
27
293
0.92
0.12
1.2
1.1
—
—
—
0
0
1120
11100
1.01
0.12
1.5
1.5
20.64
20.49
nmol/l
0.16
993
10024
30
278
1.08
0.12
1.8
1.9
9.64
9.39
mg/l
0.09
23
230
197
2019
0.97
0.12
1.5
1.3
2.08
8.03
u/ml
1.26
19
191
3231
32436
0.99
0.12
3.4
3.5
0.00
0.00
estimate
0.42
788
7152
13
114
1.14
0.11
1.0
1.0
0.12
0.16
u/ml
—
7
69
917
9079
1.01
0.11
1.5
1.6
13968282.52
45293893.91
pmol/l
1.92
809
8127
2445
24570
0.99
0.11
5.2
5.7
0.69
0.69
%
0.07
2320
23159
148
1439
1.03
0.11
1.1
1.1
17.86
12.60
au/ml
0.44
54
447
2453
24649
0.99
0.11
5.2
5.7
8.04
8.04
%
0.05
2333
23374
105
1015
1.04
0.11
1.1
1.1
—
—
—
0
0
328
3223
1.02
0.11
7.1
7.0
-0.56
0.68
mmol/l
7.44
249
2547
323
3287
0.98
0.11
2.2
2.5
1.70
1.71
%
0.09
294
2994
100
966
1.04
0.11
1.1
1.1
—
—
—
0
0
352
3463
1.02
0.10
1.3
1.4
—
—
—
0
0
3282
32934
0.99
0.10
3.4
3.5
0.01
0.30
estimate
0.85
779
7063
195
1908
1.02
0.10
1.1
1.1
—
—
—
0
0
5
44
1.14
0.10
2.6
2.8
29.80
40.91
pmol/l
—
5
34
110
1133
0.97
0.10
1.1
1.1
—
—
—
0
0
10
114
0.88
0.09
2.3
2.7
—
—
—
0
0
40
379
1.06
0.09
2.0
2.4
484.87
534.70
e6/l
0.38
31
300
169
1653
1.02
0.09
1.3
1.3
102.27
144.97
titre
0.52
22
167
20
184
1.09
0.09
1.2
1.5
10.44
5.54
%
—
9
28
53
553
0.96
0.09
1.1
1.1
—
—
—
0
0
749
7556
0.99
0.08
1.5
1.5
3.40
3.44
mmol/l
0.43
484
4948
53
508
1.04
0.08
2.3
2.7
1.61
1.47
%
0.07
46
470
761
7545
1.01
0.08
1.9
2.2
15.14
15.07
umol/l
0.10
702
7091
556
5504
1.01
0.08
2.0
2.1
378.48
375.78
nmol/l
0.14
528
5166
13
144
0.90
0.08
1.1
1.1
—
—
—
0
0
5
62
0.81
0.08
1.0
1.0
1.88
1.02
u/ml
—
5
40
5
64
0.78
0.08
1.4
1.7
—
—
—
0
0
411
4159
0.99
0.08
4.0
4.5
0.04
0.33
%
1.14
68
771
52
499
1.04
0.08
1.0
1.1
—
—
—
0
0
18
195
0.92
0.08
1.4
1.2
53.40
11.62
%
—
5
29
41
391
1.05
0.08
1.9
1.8
—
—
—
0
0
173
1697
1.02
0.08
9.4
9.1
0.68
0.69
%
0.08
173
1689
6
73
0.82
0.07
2.2
1.4
—
18.33
—
0
6
705
7107
0.99
0.07
2.3
2.5
3.93
4.20
e9/l
1.88
636
6519
315
3191
0.99
0.07
1.7
1.8
1.33
1.35
g/l
0.08
294
3025
49
510
0.96
0.07
1.1
1.1
—
—
—
0
0
32
337
0.95
0.07
1.8
3.0
—
—
—
0
0
8
78
1.03
0.07
1.0
1.0
0.07
0.49
u/ml
—
8
72
7
83
0.84
0.07
2.7
1.9
16.14
43.33
pmol/l
—
7
74
7
83
0.84
0.07
3.3
2.0
—
—
—
0
0
199
2022
0.98
0.07
1.5
1.3
7.04
7.06
u/ml
0.00
28
302
11
122
0.90
0.07
1.1
1.1
—
—
—
0
0
11
122
0.90
0.07
1.1
1.1
—
—
—
0
0
11
122
0.90
0.07
1.1
1.1
—
—
—
0
0
8
90
0.89
0.06
2.1
1.5
7.59
46.38
u/l
—
8
77
8
95
0.84
0.06
1.4
1.5
—
—
—
0
0
271
2744
0.99
0.06
7.7
7.7
113.95
121.52
g/l
7.62
266
2671
394
3979
0.99
0.06
3.6
4.1
0.70
0.65
%
0.13
76
893
5598
55940
1.01
0.06
9.2
9.5
23.82
24.12
u/l
0.52
5465
54902
133
1305
1.02
0.06
1.2
1.2
—
—
—
0
0
19
203
0.94
0.06
1.2
2.0
0.27
0.19
e9/l
—
9
96
4837
48425
0.99
0.06
3.3
3.4
1.16
1.16
mmol/l
0.33
4670
46769
134
1363
0.98
0.05
1.1
1.1
0.21
0.25
u/ml
0.08
26
397
18
192
0.94
0.05
1.3
1.2
—
—
—
0
0
43
415
1.04
0.05
1.3
1.2
11.21
23.78
u/l
1.41
37
378
159
1613
0.99
0.05
1.1
1.1
4.27
4.21
u/ml
0.01
64
771
31
323
0.96
0.05
2.4
2.8
0.83
0.84
e9/l
0.06
31
313
16
150
1.07
0.04
1.1
1.1
—
—
—
0
0
55
564
0.97
0.04
1.2
1.2
—
—
—
0
0
176
1780
0.99
0.04
1.1
1.1
2.01
1.51
u/ml
0.29
72
856
95
934
1.02
0.04
1.4
1.3
28.07
51.96
u/ml
—
6
55
5575
55723
1.01
0.04
11.1
11.8
64.34
65.07
umol/l
3.62
5516
55251
128
1295
0.99
0.03
1.1
1.1
3.58
3.15
eliau/ml
0.11
71
713
17
179
0.95
0.03
1.5
1.5
5.15
5.40
mmol/l
0.85
17
179
65
638
1.02
0.03
1.1
1.1
187.84
204.42
mg/l
0.76
56
572
179
1806
0.99
0.03
1.1
1.1
—
—
—
0
0
37
360
1.03
0.03
1.1
1.4
—
—
—
0
0
37
360
1.03
0.03
2.1
1.6
—
—
—
0
0
31
301
1.03
0.02
2.6
2.3
—
—
—
0
0
615
6130
1.00
0.02
1.7
1.8
—
—
—
0
0
970
9723
1.00
0.02
1.8
1.7
3.27
3.26
ratio
0.06
709
7011
280
2813
1.00
0.02
7.3
7.4
96.96
96.67
%
0.36
270
2698
634
6324
1.00
0.01
2.8
3.1
0.84
0.83
mmol/l
0.44
595
6040
11
117
0.94
0.01
1.3
1.0
0.20
0.66
u/ml
—
5
53
16
153
1.05
0.01
1.0
1.0
—
—
—
0
0
16
153
1.05
0.01
1.0
1.0
—
—
—
0
0
16
153
1.05
0.01
1.0
1.0
—
—
—
0
0
417
4183
1.00
0.01
3.8
4.3
0.91
0.91
%
0.01
83
947
180
1810
0.99
0.01
1.1
1.1
—
—
—
0
0
862
8634
1.00
0.01
1.3
1.3
—
—
—
0
0
68
672
1.01
0.01
1.1
1.1
9.48
1.12
u/ml
0.69
18
200
442
4430
1.00
0.01
1.3
1.4
220.94
237.21
miu/ml
0.46
237
2316
226
2252
1.00
0.01
2.5
2.5
73.30
71.61
e9/l
0.30
154
1596
14
134
1.04
0.00
1.3
1.4
8.15
8.64
mmol/l
0.20
14
134
185
1843
1.00
0.00
1.1
1.1
6.87
5.33
u/ml
0.48
80
960
29
296
0.98
0.00
1.1
1.2
—
—
—
0
0
34
334
1.02
0.00
1.4
1.6
35.20
41.82
%
0.41
23
186
405
4044
1.00
0.00
3.8
4.3
0.19
0.15
%
0.25
72
810
30
302
0.99
0.00
1.8
2.1
0.75
0.86
%
0.56
12
169
31
308
1.01
0.00
4.1
6.5
10.27
11.00
mg/l
0.37
26
289
26
265
0.98
0.00
1.1
1.1
1.43
2.88
u/ml
0.54
16
144
31
305
1.02
0.00
2.4
2.5
—
—
—
0
0
31
315
0.98
0.00
1.0
1.1
—
—
—
0
0
32
325
0.98
0.00
3.6
2.6
59.92
55.03
%
0.57
24
293
168
1678
1.00
0.00
2.0
3.1
24.51
24.25
mmol/l
0.55
168
1659
101
1015
0.99
0.00
1.4
1.4
11.18
4.53
iu/ml
—
6
19
268
2682
1.00
0.00
2.2
3.1
1.82
1.73
mmol/l
0.15
236
2331
309
3092
1.00
0.00
3.8
3.8
12.32
32.59
ug/l
0.85
207
2207
11
106
1.04
0.00
1.1
1.7
—
—
—
0
0
13
127
1.02
0.00
1.2
1.1
—
—
—
0
0
375
3755
1.00
0.00
1.2
1.2
—
—
—
0
0
18
177
1.02
0.00
1.2
1.8
—
—
—
0
0
2522
25222
1.00
0.00
5.0
5.5
56.10
56.07
%
0.06
2437
24296
66
656
1.01
0.00
1.2
1.2
33.86
37.29
mg/l
0.40
56
556
34
337
1.01
0.00
2.6
2.2
—
—
—
0
0
54
537
1.01
0.00
1.0
1.0
—
—
—
0
0
11
109
1.01
0.00
1.2
1.4
—
—
—
0
0
175
1751
1.00
0.00
1.1
1.1
0.71
1.15
u/ml
0.77
58
724
0
5
0.00
0.00
0.0
3.0
—
102.60
—
0
5
0
5
0.00
0.00
0.0
1.6
—
160.20
—
0
5
5
52
0.96
0.00
1.6
1.8
5.00
17.52
ug/l
—
5
52
9
89
1.01
-0.00
1.1
1.6
63.78
40.94
%
—
9
77
0
6
0.00
-0.00
0.0
1.8
—
51.83
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
59.44
—
0
9
31
310
1.00
-0.00
1.3
1.5
5424.93
31215.46
e6/l
1.52
14
212
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.8
—
1.43
—
0
9
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1181.67
—
0
6
0
7
0.00
-0.00
0.0
6.9
—
312.57
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
79
0.89
-0.00
2.0
2.3
1.81
2.81
ug/l
—
7
73
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
65
0.92
-0.00
1.7
2.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
8.3
—
10.20
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
0.03
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
1.28
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
26.58
—
0
8
0
7
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.7
—
14.87
—
0
7
62
620
1.00
-0.00
1.2
1.1
1.05
1.05
ratio
0.12
50
524
0
6
0.00
-0.00
0.0
1.8
—
0.53
—
0
6
41
410
1.00
-0.00
1.1
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
4.46
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_POSTPART_HAEMORRH_PLACENTA and mortality.

Females

Parameter HR [95% CI] p-value
O15_POSTPART_HAEMORRH_PLACENTA 0.584 [0.46, 0.74] < 0.001
Birth year 0.994 [0.99, 1.0] 0.144

During the follow-up period (1.1.1998 — 31.12.2019), 93 out of 19150 females with O15_POSTPART_HAEMORRH_PLACENTA died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_POSTPART_HAEMORRH_PLACENTA.

N-year risk Females Males
1 0.043% No data
5 0.36% No data
10 0.906% No data
15 1.602% No data
20 2.71% No data

Relationships between endpoints

Index endpoint: O15_POSTPART_HAEMORRH_PLACENTA – Postpartum haemorrhage due to retained placenta

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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