Supernumerary teeth EXCLUDE clefts and syndromes

K11_SUPNUM_ONLY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • not K11_SUPNUM_EXCLUDE
557225

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K00.1
  • Cause of death: ICD-10 K00.1

2 out of 7 registries used, show all original rules.

175

4. Check minimum number of events

None

175

5. Include endpoints

None

175

6. Filter based on genotype QC (FinnGen only)

158

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3723 1455 2264
Only index persons 3237 1262 1975
Unadjusted period prevalence (%)
Whole population 0.05 0.04 0.06
Only index persons 0.06 0.05 0.08
Median age at first event (years)
Whole population 10.23 10.55 9.98
Only index persons 10.76 11.25 10.45

-FinnGen-

Key figures

All Female Male
Number of individuals 158 85 73
Unadjusted period prevalence (%) 0.03 0.03 0.03
Median age at first event (years) 14.50 14.74 14.23

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
165
Matched controls
1650
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K00.10
ICD-10 Finland
The incisor and canine region, including the mesiodens
1164.2
110.6
96
*
K00.11
ICD-10 Finland
Excess teeth in the premolar region
+∞
25.7
24
*
K00.12
ICD-10 Finland
Excess teeth in the molar region
+∞
24.6
23
*
K00.19
ICD-10 Finland
Indefinite redundant teeth
139.4
23.2
24
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
9.6
21.1
27
33
EBA10
NOMESCO Finland
Operative extraction of tooth
4.5
20.9
87
325
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
4.7
11.2
29
72
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
5.2
11.1
25
55
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
16.3
9.7
15
10
K00.1
ICD-10 Finland
Supernumerary teeth
+∞
9.5
9
*
SAA04
NOMESCO Finland
Special examination of mouth
3.7
8.4
29
89
K01.0
ICD-10 Finland
Embedded teeth
6.7
8.2
20
33
ECA00
NOMESCO Finland
Surgical exposure of tooth
17.6
6.8
10
6
EBB10
NOMESCO Finland
Insertion of dental implant
41.8
6.8
8
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
62
394
1.92
3.79
8.8
6.0
1.11
1.07
inr
0.45
52
329
31
165
2.08
3.07
1.3
1.6
3.09
3.42
mmol/l
1.02
22
114
18
79
2.44
2.79
2.4
5.7
0.20
0.25
%
—
5
20
91
695
1.69
2.77
7.9
7.9
0.55
0.55
e9/l
0.11
80
600
91
696
1.69
2.75
8.1
7.9
0.04
0.04
e9/l
0.25
80
601
93
719
1.67
2.67
7.9
8.4
0.19
0.19
e9/l
0.08
83
639
94
729
1.67
2.66
8.0
7.7
2.06
2.00
e9/l
0.31
84
655
64
450
1.69
2.63
8.6
8.8
—
—
—
0
0
7
15
4.82
2.62
1.3
1.5
—
—
—
0
0
18
83
2.31
2.52
17.1
7.6
—
—
—
0
0
27
147
2.00
2.52
1.6
1.6
—
—
—
0
0
5
155
0.30
2.44
1.2
2.2
2.41
2.41
mmol/l
—
5
140
6
12
5.14
2.42
1.5
8.1
—
—
—
0
0
18
85
2.25
2.39
2.4
5.5
1.20
0.89
%
—
5
27
5
8
6.40
2.39
5.4
3.1
70.40
45.25
umol/l
—
5
8
97
772
1.62
2.37
9.1
9.9
3.99
4.05
e9/l
0.09
88
665
17
79
2.28
2.34
2.5
5.3
0.60
0.50
%
—
5
23
27
153
1.91
2.25
2.0
2.1
—
—
—
0
0
153
1392
2.36
2.24
16.3
12.3
68.64
69.65
umol/l
0.31
153
1377
12
49
2.56
2.16
6.3
8.7
189.43
446.03
mg/l
—
7
31
57
408
1.61
2.11
2.8
2.4
—
—
—
0
0
154
1414
2.34
2.04
14.0
9.2
—
—
—
0
0
9
34
2.74
1.89
2.6
1.8
—
—
—
0
0
46
320
1.61
1.89
3.4
4.5
—
—
—
0
0
20
110
1.93
1.82
2.3
3.4
10.78
10.14
g/l
0.18
20
102
46
324
1.58
1.79
3.2
2.5
19.79
32.42
ng/l
0.37
25
144
7
24
3.00
1.74
2.0
8.7
—
—
—
0
0
148
1355
1.90
1.73
17.2
11.7
16.54
21.09
mg/l
1.51
123
1041
5
14
3.65
1.62
1.0
1.0
—
—
—
0
0
8
32
2.57
1.62
1.6
4.2
—
—
—
0
0
22
131
1.78
1.59
1.2
1.2
—
—
—
0
0
61
468
1.48
1.59
12.7
10.8
1.22
1.22
mmol/l
0.34
56
442
17
93
1.92
1.58
1.7
2.1
1.11
1.07
g/l
0.09
17
87
35
238
1.60
1.57
4.1
4.6
—
—
—
0
0
36
250
1.56
1.48
3.5
2.3
—
—
—
0
0
74
597
1.43
1.46
3.6
3.0
—
—
estimate
—
0
0
5
16
3.19
1.45
3.6
6.2
3.42
5.89
pmol/l
—
5
16
5
16
3.19
1.45
1.0
1.1
—
—
—
0
0
7
29
2.47
1.41
4.1
4.5
3.04
3.71
e9/l
—
7
29
73
592
1.42
1.38
3.8
3.0
6.38
6.28
ph
0.41
42
317
6
23
2.67
1.38
1.0
1.2
—
—
—
0
0
65
521
1.41
1.30
2.6
2.3
—
—
—
0
0
64
512
1.41
1.29
13.1
10.2
1.22
1.22
mmol/l
0.05
55
449
18
108
1.75
1.28
1.3
1.5
274.17
265.19
miu/ml
—
6
60
8
36
2.28
1.26
3.8
3.9
49.63
55.76
%
—
8
36
120
1077
1.42
1.18
5.2
4.0
14.35
14.60
pmol/l
0.63
115
986
0
33
0.00
1.17
0.0
18.9
—
1.22
—
0
27
46
353
1.42
1.16
3.8
3.3
0.18
0.01
estimate
0.44
11
136
5
20
2.54
1.16
5.0
4.3
5.22
4.97
kpa
—
5
20
5
20
2.54
1.16
5.0
4.4
9.42
9.48
kpa
—
5
20
10
51
2.02
1.14
1.6
1.6
—
0.05
estimate
—
0
21
13
74
1.82
1.10
1.2
1.1
1.70
3.85
u/ml
—
6
51
5
21
2.42
1.10
3.4
2.5
2.92
11.50
u/ml
—
5
21
16
100
1.66
1.01
24.4
21.4
24.63
25.01
mmol/l
0.17
16
100
6
27
2.27
0.94
4.5
4.1
7.40
7.41
ph
—
6
27
135
1255
1.42
0.93
5.6
4.8
1.87
1.79
mu/l
0.41
128
1193
17
111
1.59
0.92
1.9
1.5
—
—
—
0
0
6
29
2.11
0.90
1.0
1.0
—
—
—
0
0
23
163
1.48
0.88
2.3
2.0
—
—
—
0
0
6
30
2.04
0.88
1.2
1.0
—
—
—
0
0
12
72
1.72
0.88
1.0
1.4
—
—
—
0
0
6
31
1.97
0.85
1.3
1.2
—
—
—
0
0
12
73
1.69
0.84
1.3
1.5
—
—
—
0
0
17
115
1.53
0.80
11.9
16.7
—
—
—
0
0
48
396
1.30
0.76
1.8
1.7
98.87
96.18
pmol/l
0.15
33
207
5
24
2.12
0.75
4.2
4.8
—
—
—
0
0
39
313
1.32
0.75
2.0
1.7
—
—
—
0
0
7
41
1.74
0.71
9.0
27.2
0.60
0.60
%
—
7
41
96
868
1.25
0.70
11.0
6.7
92.89
80.23
u/l
1.35
91
820
5
28
1.81
0.66
1.0
1.3
—
—
—
0
0
14
95
1.52
0.66
11.8
13.4
24.15
23.92
mmol/l
0.10
14
95
7
44
1.62
0.66
9.0
25.5
0.97
1.58
%
—
7
44
7
44
1.62
0.66
1.1
1.1
—
—
—
0
0
47
394
1.27
0.65
7.0
7.3
—
—
—
0
0
10
152
0.64
0.65
1.3
1.3
—
—
—
0
0
159
1547
1.76
0.64
23.6
17.2
137.30
138.27
g/l
0.39
159
1533
159
1546
1.78
0.64
23.4
16.9
29.85
29.87
pg
0.05
159
1531
159
1546
1.78
0.64
23.6
17.8
41.08
41.12
%
0.04
159
1530
159
1545
1.80
0.64
23.3
16.9
89.10
88.92
fl
0.22
159
1531
40
331
1.28
0.62
4.5
2.6
1.01
1.02
kg/l
0.92
24
210
17
123
1.43
0.61
11.0
11.1
5.65
5.83
kpa
0.34
17
118
17
125
1.40
0.56
11.0
10.9
0.83
1.67
mmol/l
0.41
17
95
11
74
1.52
0.55
1.0
1.1
0.88
0.87
g/l
0.06
11
74
32
262
1.27
0.54
2.8
2.6
0.90
1.27
mg/l
0.41
24
183
15
109
1.41
0.53
1.7
1.8
6.13
6.19
ph
—
8
72
18
137
1.35
0.50
1.3
1.3
145.34
113.26
u/ml
—
7
53
20
155
1.33
0.49
3.0
2.6
4189.43
4750.53
u/l
0.07
14
65
11
76
1.48
0.49
1.2
1.3
—
—
—
0
0
36
303
1.24
0.49
5.1
3.9
7.40
7.39
ph
0.54
29
215
39
453
0.82
0.47
2.4
2.0
—
—
—
0
0
5
83
0.59
0.47
1.0
1.1
—
—
—
0
0
42
363
1.21
0.45
4.5
3.9
7.24
52.09
e6/l
1.66
34
272
77
704
1.18
0.44
4.0
3.4
0.00
0.00
estimate
-0.00
13
142
5
31
1.63
0.43
2.4
2.7
92.00
479.63
ug/l
—
5
31
43
375
1.20
0.42
1.8
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
42
478
0.84
0.41
1.8
1.8
1.12
1.32
mmol/l
1.15
35
424
7
103
0.67
0.41
2.0
1.5
—
—
—
0
0
8
60
1.35
0.41
3.3
1.5
—
—
—
0
0
7
104
0.66
0.41
2.1
1.6
—
—
—
0
0
16
203
0.77
0.41
1.3
1.2
—
—
—
0
0
131
1256
1.21
0.40
16.9
14.9
13.22
13.15
%
0.32
131
1243
77
709
1.16
0.39
4.0
3.4
0.00
0.00
estimate
-0.00
13
139
38
434
0.84
0.39
2.9
2.9
—
0.00
—
0
6
5
36
1.40
0.38
1.4
1.9
—
—
—
0
0
15
190
0.77
0.38
1.4
3.0
124.50
228.69
ng/l
—
8
108
52
466
1.17
0.37
5.0
4.7
14.11
31.20
e6/l
1.23
40
296
119
1136
1.17
0.36
3.7
3.2
5.39
5.57
mmol/l
0.97
111
1050
133
1281
1.20
0.36
17.4
14.5
334.44
334.90
g/l
0.28
133
1273
77
713
1.15
0.36
3.8
3.5
0.00
0.00
estimate
-0.00
14
132
10
73
1.39
0.35
1.0
1.1
1.58
1.51
g/l
—
10
73
14
109
1.31
0.35
6.4
15.0
104.71
104.39
mmol/l
0.08
14
109
16
128
1.28
0.33
1.8
1.6
—
—
—
0
0
6
47
1.29
0.32
1.2
2.7
36.00
92.93
ng/l
—
6
42
17
206
0.81
0.31
1.6
1.7
—
—
—
0
0
33
291
1.17
0.29
2.6
2.7
88.27
87.33
ug/g
0.01
28
224
36
322
1.15
0.26
3.0
3.9
0.20
0.25
e6/l
0.18
26
231
54
497
1.13
0.26
2.1
1.9
—
—
—
0
0
5
75
0.66
0.26
1.0
1.1
—
—
—
0
0
61
655
0.89
0.26
12.7
10.5
0.00
0.00
e9/l
0.80
52
522
36
324
1.14
0.24
1.5
2.2
—
—
—
0
0
57
530
1.12
0.23
2.0
1.8
—
—
—
0
0
48
442
1.12
0.23
2.5
1.8
—
—
—
0
0
38
417
0.88
0.23
4.2
2.7
0.25
0.00
estimate
0.47
12
118
7
92
0.75
0.23
1.3
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.6
—
1546.50
—
0
10
0
10
0.00
0.21
0.0
9.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
13.51
—
0
12
0
12
0.00
0.21
0.0
1.0
—
1653.08
—
0
12
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
6.6
—
9.23
—
0
13
0
13
0.00
0.21
0.0
3.3
—
45.38
—
0
13
49
455
1.11
0.20
1.7
1.6
2.16
2.04
g/l
0.38
33
274
0
14
0.00
0.20
0.0
1.1
—
102.50
—
0
14
14
119
1.19
0.18
1.3
1.9
—
—
—
0
0
22
196
1.14
0.17
2.7
3.9
8.84
3.21
e6/l
0.62
12
108
5
67
0.74
0.17
1.2
1.7
—
5.36
—
0
19
12
101
1.20
0.17
1.7
1.6
0.13
0.25
mg/l
—
6
45
86
892
0.93
0.16
6.6
4.3
—
—
—
0
0
9
80
1.13
0.15
1.9
1.2
—
—
—
0
0
21
189
1.13
0.14
1.3
1.3
—
—
—
0
0
20
221
0.89
0.13
1.4
1.3
0.94
7.43
u/ml
—
10
89
21
230
0.90
0.12
5.1
3.7
24.54
70.89
mg/l
1.75
14
156
26
240
1.10
0.12
1.4
1.3
10.27
22.37
iu/ml
—
6
61
14
124
1.14
0.11
2.1
1.9
—
—
—
0
0
55
527
1.07
0.11
4.2
2.9
0.23
0.01
estimate
0.45
13
122
16
176
0.90
0.10
1.4
1.8
—
—
—
0
0
55
529
1.06
0.09
1.6
1.5
0.51
1.77
u/ml
2.13
15
118
14
126
1.12
0.09
1.8
1.2
—
—
—
0
0
14
126
1.12
0.09
2.7
3.6
—
—
—
0
0
21
225
0.92
0.08
1.7
1.7
—
—
—
0
0
9
83
1.09
0.07
7.6
20.9
4.68
5.15
kpa
—
9
78
9
83
1.09
0.07
7.6
20.9
16.62
15.55
kpa
—
9
78
14
129
1.09
0.06
2.5
2.6
30.07
28.31
u/l
0.12
14
105
21
200
1.06
0.04
1.5
1.6
—
—
—
0
0
14
148
0.94
0.02
1.6
2.1
—
—
—
0
0
22
228
0.96
0.02
6.0
4.3
3.36
10.94
mg/mmol
1.55
14
152
22
224
0.98
0.00
1.6
1.7
—
—
—
0
0
23
231
0.99
0.00
3.3
3.6
311.09
329.43
umol/l
0.37
23
217
64
643
0.99
0.00
2.6
2.4
—
—
—
0
0
22
225
0.97
0.00
1.6
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
187.50
—
0
8
0
8
0.00
0.00
0.0
1.3
—
0.00
—
0
8
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
11.29
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
22
220
1.00
-0.00
1.6
1.7
—
—
—
0
0
9
90
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
3.25
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
2.2
12.1
0.54
0.60
%
—
5
49
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
51.83
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
86
0.93
-0.00
1.4
2.3
—
—
—
0
0
6
67
0.89
-0.00
7.0
2.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_SUPNUM_ONLY and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_SUPNUM_ONLY.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_SUPNUM_ONLY – Supernumerary teeth EXCLUDE clefts and syndromes

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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