Ménière disease

H8_MENIERE

endolymphatic hydrops: An accumulation of endolymph in the inner ear (labyrinth) leading to buildup of pressure and distortion of intralabyrinthine structures, such as cochlea and semicircular canals. It is characterized by sensorineural hearing loss; tinnitus; and sometimes vertigo.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H81.0
  • Hospital discharge: ICD-9 3860
  • Hospital discharge: ICD-8 38599
  • Cause of death: ICD-10 H81.0
  • Cause of death: ICD-9 3860
  • Cause of death: ICD-8 38599

2 out of 7 registries used, show all original rules.

4270

4. Check minimum number of events

None

4270

5. Include endpoints

None

4270

6. Filter based on genotype QC (FinnGen only)

3894

Control definitions (FinnGen only)

Control exclude
H8_INNER

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H81
Name in latin
Morbus Ménière

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26706 17134 9455
Only index persons 24436 15945 8491
Unadjusted period prevalence (%)
Whole population 0.41 0.49 0.26
Only index persons 0.50 0.59 0.32
Median age at first event (years)
Whole population 57.15 57.45 56.61
Only index persons 56.64 56.87 56.19

-FinnGen-

Key figures

All Female Male
Number of individuals 3894 2537 1357
Unadjusted period prevalence (%) 0.80 0.90 0.62
Median age at first event (years) 56.08 54.87 58.34

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3995
Matched controls
39950
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
7.3
307.7
816
1355
Z01.1
ICD-10 Finland
Examination of ears and hearing
5.9
307.7
1458
3558
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
11.0
307.7
410
412
H81.3
ICD-10 Finland
Other peripheral vertigo
37.7
307.7
529
161
N07CA01
ATC
betahistine; oral
105.2
307.7
3109
1290
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
14.1
307.7
781
678
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
3.9
307.7
1431
4975
H81.2
ICD-10 Finland
Vestibular neuronitis
83.6
307.7
176
22
DFF59
NOMESCO Finland
Other assessment of balance
34.3
307.7
254
79
DFF00
NOMESCO Finland
Pure tone audiometry
6.4
307.7
1169
2431
N05AB04
ATC
prochlorperazine; systemic, rectal
13.1
307.7
421
356
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
4.4
307.7
1433
4492
R42
ICD-10 Finland
Dizziness and giddiness
7.1
307.7
2250
6110
H81.0
ICD-10 Finland
Ménière disease
11894.2
307.7
3790
62
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
16.8
288.8
245
155
C03EA02
ATC
trichlormethiazide and potassium-sparing agents; oral
10.2
269.9
315
334
UDC00
NOMESCO Finland
Ear microscopy
4.8
254.5
643
1525
38599
ICD-8 Finland
Ménière's disease
+∞
222.0
211
*
H81.9
ICD-10 Finland
Disorder of vestibular function, unspecified
21.5
217.1
163
79
DFF50
NOMESCO Finland
Electronystagmography
88.6
213.0
112
13
DFF15
NOMESCO Finland
Speech audiometry
5.0
205.0
485
1082
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
13.2
188.0
181
143
3860A
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Ménière's disease
+∞
177.4
169
*
H93.1
ICD-10 Finland
Tinnitus
3.9
156.1
513
1461
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.7
153.8
540
1609
Z97.4
ICD-10 Finland
Presence of external hearing-aid
4.2
146.6
423
1095
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
4.0
141.5
441
1207
H02
ICPC
Hearing complaint
2.7
137.8
945
4135
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
30.0
133.1
88
30
H82
ICPC
Vertiginous syndrome
7.1
124.5
191
280
N17
ICPC
Vertigo/dizziness
2.7
116.4
772
3295
A03FA01
ATC
metoclopramide; systemic, rectal
2.3
110.4
1199
6376
DAX08
NOMESCO Finland
Fitting of hearing aid
3.2
96.2
406
1345
DFE00
NOMESCO Finland
Insertion of cochlear implant
23.6
90.3
65
28
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.8
87.8
279
768
Z3229
NOMESCO Finland
Other healthcare associate professional
2.8
87.4
485
1872
DC1AD
NOMESCO Finland
Temporalbone CT
8.8
86.2
109
127
SPAT1043
SPAT
Audiometry
2.4
74.7
573
2580
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
6.3
73.3
124
201
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
71.3
647
3130
R5120
NOMESCO Finland
Preparation of an aid
3.8
68.5
220
609
H80.0
ICD-10 Finland
Otosclerosis involving oval window, nonobliterative
342.9
67.7
68
*
H02AB06
ATC
prednisolone; systemic
1.8
66.5
2077
15156
7804A
ICD-9 Finland
General symptoms, Dizziness and giddiness
6.2
59.4
103
171
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.8
59.2
314
1176
H29
ICPC
Ear symptom/complaint other
2.1
58.6
618
3157
DFX00
NOMESCO Finland
Connecting cochlear implant
19.8
58.1
45
23
G44.2
ICD-10 Finland
Tension-type headache
2.1
57.1
624
3230
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
3.5
56.5
203
605
78050
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Vertigo
6.2
55.0
95
157
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
4.6
52.6
127
284
H81.4
ICD-10 Finland
Vertigo of central origin
11.1
52.0
55
50
AA1AD
NOMESCO Finland
CT of head and brain
1.7
51.5
1301
8766
H81
ICD-10 Finland
Disorders of vestibular function
17.6
48.9
40
23
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
5.7
47.3
89
160
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
45.7
493
2526
R51.80
ICD-10 Finland
Headache
1.9
45.6
650
3673
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
44.2
977
6299
DFF16
NOMESCO Finland
Speech-in-noise audiometry
16.8
41.9
35
21
H80.9
ICD-10 Finland
Otosclerosis, unspecified
148.3
41.8
44
*
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.1
41.4
175
576
DE2CM
NOMESCO Finland
Acoustic channel extensive MRI examination with 3 Tesla magnet
13.1
40.8
39
30
A02BC05
ATC
esomeprazole; systemic
1.6
40.5
1682
12636
R06AE53
ATC
cyclizine, combinations; systemic
6.3
40.3
68
110
R01AD09
ATC
mometasone; nasal
1.6
39.2
1740
13238
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
37.9
1436
10522
4173
FHL
Surgery on Saccus endolymphaticus
+∞
37.6
36
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.1
37.4
370
1828
R01AD08
ATC
fluticasone; nasal
1.6
36.6
1105
7662
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
36.1
1185
8376
M03BX02
ATC
tizanidine; oral
1.5
34.1
2354
19456
DDA00
NOMESCO Finland
Stapedotomy
121.1
33.7
36
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
4.5
33.1
80
179
H53.1
ICD-10 Finland
Subjective visual disturbances
2.1
32.6
320
1574
H80.1
ICD-10 Finland
Otosclerosis involving oval window, obliterative
+∞
32.3
31
*
R11
ICD-10 Finland
Nausea and vomiting
2.0
32.2
385
2037
H13
ICPC
Plugged feeling ear
1.6
32.1
831
5522
M54.5
ICD-10 Finland
Low back pain
1.5
31.9
1430
10764
A02BC03
ATC
lansoprazole; oral
1.5
31.6
1174
8485
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
31.6
879
5944
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
4.1
30.6
84
208
M25.5
ICD-10 Finland
Pain in joint
1.5
30.3
1293
9609
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.0
30.2
378
2030
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
29.3
1202
8843
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
4.5
29.2
71
160
M01AH05
ATC
etoricoxib; oral
1.5
28.7
2376
20020
M79.6
ICD-10 Finland
Pain in limb
1.5
28.4
1736
13806
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.0
28.2
350
1872
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
28.2
522
3165
UJF32
NOMESCO Finland
Coloscopy
1.5
28.1
1084
7862
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
27.5
1164
8596
A02BC02
ATC
pantoprazole; systemic
1.5
27.5
2744
23863
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
27.1
302
1555
N02BE01
ATC
paracetamol; systemic, rectal
1.8
27.0
3554
32800
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
26.3
1155
8579
H81.8
ICD-10 Finland
Other disorders of vestibular function
23.3
26.1
37
16
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
26.1
427
2495
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
25.8
726
4896
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
25.6
1097
8101
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
25.2
1793
14552
R03AC02
ATC
salbutamol; inhalant
1.4
25.0
2067
17214
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
24.8
1136
8490
R01AD58
ATC
fluticasone, combinations; nasal
1.5
24.7
861
6083
Z97.8
ICD-10 Finland
Presence of other specified devices
6.4
24.3
40
63
N03AX12
ATC
[U] gabapentin; oral
1.6
24.0
645
4293
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
23.8
2605
22695
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
23.8
696
4728
H92.0
ICD-10 Finland
Otalgia
2.1
23.7
248
1248
R06.0
ICD-10 Finland
Dyspnoea
1.5
23.0
1094
8214
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
22.4
868
6253
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
22.4
739
5149
L01
ICPC
Neck symptom/complaint
1.6
22.3
621
4165
R53
ICD-10 Finland
Malaise and fatigue
1.5
22.2
968
7140
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
22.2
985
7291
J01DB01
ATC
cefalexin; oral
1.5
22.2
3148
28546
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.8
22.1
351
2028
L03
ICPC
Low back symptom/complaint
1.4
22.0
1105
8371
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
22.0
699
4829
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.8
21.9
336
1923
XF404
NOMESCO Finland
Ambulatory ECG
1.8
21.8
350
2030
G47.3
ICD-10 Finland
Sleep apnoea
1.5
21.7
812
5805
SFA20
NOMESCO Finland
Two-surface restoration
1.4
21.6
2070
17494
N06AX11
ATC
mirtazapine; oral
1.4
21.5
1304
10208
Z01.2
ICD-10 Finland
Dental examination
1.4
21.4
1646
13412
H91.8
ICD-10 Finland
Other specified hearing loss
3.8
21.3
65
174
SFA10
NOMESCO Finland
One-surface restoration
1.4
21.3
1955
16390
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
21.0
1973
16586
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.0
20.7
234
1211
R07.3
ICD-10 Finland
Other chest pain
1.7
20.6
416
2572
A02BC01
ATC
omeprazole; systemic
1.4
20.6
1042
7887
J01AA02
ATC
doxycycline; systemic
1.4
20.4
3017
27271
M01AE02
ATC
naproxen; oral, rectal
1.4
20.2
2044
17349
N06AX21
ATC
duloxetine; oral
1.6
20.1
463
2961
DFA00
NOMESCO Finland
Saccotomy
+∞
19.8
19
*
C07AB07
ATC
bisoprolol; oral
1.4
19.8
1939
16353
J01MA02
ATC
ciprofloxacin; systemic
1.4
19.6
1453
11716
M01AB05
ATC
diclofenac; systemic, rectal
1.4
19.6
2456
21502
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
19.6
1633
13418
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
19.6
2347
20406
A04AA01
ATC
ondansetron; systemic, rectal
1.7
19.4
344
2051
R05
ICD-10 Finland
Cough
1.5
19.3
822
6013
H04.10
ICD-10 Finland
Dry eye syndrome
1.6
19.3
472
3063
K02.1
ICD-10 Finland
Caries of dentine
1.4
19.2
2037
17357
RK520, ,
NOMESCO Finland
6.7
19.1
30
45
R03BA05
ATC
fluticasone; inhalant
1.5
18.8
652
4574
3882A
ICD-9 Finland
Other disorders of ear, Sudden hearing loss, unspecified
15.9
18.8
30
19
J01CA04
ATC
amoxicillin; systemic
1.4
18.7
3049
27750
A02BC04
ATC
rabeprazole; oral
1.7
18.5
340
2048
N02AX02
ATC
tramadol; systemic, rectal
1.4
18.3
1616
13353
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
18.2
1859
15702
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
18.1
568
3901
H28
ICPC
Limited function/disability (H)
3.4
18.1
63
185
SPAT1263
SPAT
Sampling
1.4
18.1
1510
12368
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
2.9
18.0
84
294
J01FA10
ATC
azithromycin; systemic
1.3
17.6
1998
17108
K30
ICD-10 Finland
Functional dyspepsia
1.6
17.6
437
2845
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.6
17.5
415
2670
A98
ICPC
Health maint/preventive medicine
1.8
17.5
3759
35868
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
17.4
396
2521
H02AB04
ATC
methylprednisolone; systemic
1.5
17.3
540
3699
J01FA06
ATC
roxithromycin; oral
1.3
17.3
1475
12092
S18
ICPC
Laceration/cut
1.3
17.3
1801
15208
J02AC01
ATC
fluconazole; systemic
1.3
17.2
1437
11745
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
17.1
756
5557
TDA90
NOMESCO Finland
Removal wax from ear
3.3
17.1
65
202
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
17.0
616
4353
R4110, ,
SPAT
1.5
17.0
539
3705
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
17.0
1561
12932
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
17.0
1851
15721
R01AD12
ATC
fluticasone furoate; nasal
1.4
17.0
1050
8180
3891A
ICD-9 Finland
Deafness, Sensorineural deafness
16.0
17.0
27
17
G43.9
ICD-10 Finland
Migraine, unspecified
2.0
17.0
194
1008
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
16.9
310
1865
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.6
16.7
413
2682
R20.2
ICD-10 Finland
Paraesthesia of skin
1.8
16.7
253
1441
N03AE01
ATC
clonazepam; systemic
1.9
16.7
221
1207
N03AX16
ATC
[U] pregabalin
1.4
16.5
858
6486
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
16.5
758
5607
C10AA07
ATC
rosuvastatin; oral
1.4
16.5
1283
10359
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.0
16.4
70
233
M01AX17
ATC
nimesulide; oral
1.4
16.3
912
6980
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
16.2
383
2460
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
16.2
955
7372
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
16.1
905
6932
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
16.0
1514
12565
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
15.9
452
3032
SPAT1260
SPAT
Consultation of another employee
1.5
15.8
640
4617
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
15.8
949
7345
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
15.7
1594
13351
R55
ICD-10 Finland
Syncope and collapse
1.6
15.7
423
2803
M79.1
ICD-10 Finland
Myalgia
1.5
15.7
530
3690
J01DA01
ATC
[U] cefalexin
1.3
15.7
2262
19892
SPAT1153
SPAT
Removal of sutures
1.4
15.6
1178
9445
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
15.6
585
4158
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.9
15.6
204
1110
N06AA09
ATC
amitriptyline; systemic
1.6
15.4
373
2411
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
15.4
1449
12002
R06AE07
ATC
cetirizine; oral
1.3
15.3
1570
13153
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
15.2
234
1338
C07AA05
ATC
propranolol; systemic
1.4
15.2
685
5043
R05
ICPC
Cough
1.4
15.1
907
7013
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
15.1
1911
16473
A02BA02
ATC
ranitidine; systemic
1.4
14.9
724
5399
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
14.7
480
3316
3861A
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Other and unspecified peripheral vertigo
+∞
14.6
14
*
H83.1
ICD-10 Finland
Labyrinthine fistula
+∞
14.6
14
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
14.6
275
1667
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
14.6
710
5294
H81
ICPC
Excessive ear wax
1.4
14.6
672
4962
R03DC03
ATC
montelukast; oral
1.5
14.5
586
4222
SPAT1312
SPAT
General health counselling
1.3
14.4
1083
8661
J35.0
ICD-10 Finland
Chronic tonsillitis
2.1
14.4
141
694
H01
ICPC
Ear pain/earache
1.6
14.3
390
2589
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
14.3
502
3518
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
14.3
1340
11059
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
4.4
14.2
35
80
H03
ICPC
Tinnitus, ringing/buzzing ear
2.4
14.0
91
377
SPAT1097
SPAT
Recording of ECG
1.5
13.9
540
3859
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
13.8
690
5162
SPAT1301
SPAT
No procedures
1.3
13.8
1130
9142
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
3.7
13.8
42
113
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.5
13.8
401
2702
DC1AI
NOMESCO Finland
Cone beam CT of ear
20.1
13.8
20
10
J01EA01
ATC
trimethoprim; systemic
1.3
13.7
988
7844
P01AB01
ATC
metronidazole; oral, rectal
1.3
13.6
1430
11965
XQ800
NOMESCO Finland
Prick test
1.7
13.6
237
1405
P06
ICPC
Sleep disturbance
1.5
13.6
429
2939
R02
ICPC
Shortness of breath/dyspnoea
1.5
13.6
520
3704
SPAT1310
SPAT
Counselling related to known health issue
1.3
13.6
1110
8970
J01FA09
ATC
clarithromycin; systemic
1.3
13.5
1070
8606
UKC02
NOMESCO Finland
Cystoscopy
1.4
13.5
566
4106
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.8
13.5
212
1222
R21
ICPC
Throat symptom/complaint
1.4
13.4
610
4487
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
13.4
1497
12628
H61.2
ICD-10 Finland
Impacted cerumen
1.7
13.3
262
1608
L08
ICPC
Shoulder symptom/complaint
1.4
13.2
858
6696
N02BF01
ATC
gabapentin; oral
1.5
13.2
390
2636
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.8
13.1
188
1055
D82
ICPC
Teeth/gum disease
1.3
13.0
1215
9991
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
12.9
2563
23203
R06AX27
ATC
desloratadine; oral
1.3
12.9
941
7471
SFA30
NOMESCO Finland
Three-surface restoration
1.3
12.9
1472
12431
L17
ICPC
Foot/toe symptom/complaint
1.3
12.9
1127
9185
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
12.9
969
7731
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.0
12.8
135
683
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.5
12.8
406
2786
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.5
12.7
381
2581
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
12.6
1287
10705
R4135
NOMESCO Finland
Rehabilitation for hearing problems
2.4
12.5
84
354
N05BB51
ATC
hydroxyzine, combinations; systemic
13.2
12.4
21
16
J31.0
ICD-10 Finland
Chronic rhinitis
1.6
12.3
290
1860
P01
ICPC
Feeling anxious/nervous/tense
1.6
12.2
323
2128
M48.0
ICD-10 Finland
Spinal stenosis
1.5
12.2
476
3401
R01AD01
ATC
beclometasone; nasal
1.4
12.2
527
3838
H66.9
ICD-10 Finland
Otitis media, unspecified
1.8
12.2
185
1056
TDA90, ,
SPAT
1.6
12.0
260
1633
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.7
12.0
227
1377
SGA01
NOMESCO Finland
Emergency treatment
1.4
12.0
487
3506
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.3
12.0
852
6731
L13
ICPC
Hip symptom/complaint
1.4
11.9
762
5922
R74
ICPC
Upper respiratory infection acute
1.3
11.9
989
7990
M54.6
ICD-10 Finland
Pain in thoracic spine
1.6
11.8
249
1554
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.6
11.8
291
1887
KMAK, ,
NOMESCO Finland
1.3
11.7
1695
14685
SPAT1325
SPAT
Vaccination
1.3
11.7
1197
9933
M01AG02
ATC
tolfenamic acid; oral, rectal
1.4
11.7
508
3700
XF402
NOMESCO Finland
ECG with work load test
1.5
11.7
378
2602
R00.2
ICD-10 Finland
Palpitations
1.6
11.7
275
1764
XA402
NOMESCO Finland
ENMG
2.2
11.6
94
430
H60.3
ICD-10 Finland
Other infective otitis externa
2.3
11.6
89
399
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.3
11.5
805
6342
F51.0
ICD-10 Finland
Nonorganic insomnia
1.4
11.5
539
3983
3870A
ICD-9 Finland
Otosclerosis involving oval window, nonobliterative
+∞
11.5
11
*
H53.2
ICD-10 Finland
Diplopia
2.0
11.5
124
634
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.3
11.4
1015
8264
DE2CF
NOMESCO Finland
Acoustic channel extensive MRI examination with median intensity magnet
120.4
11.4
12
*
N06AB04
ATC
citalopram; systemic
1.4
11.4
732
5689
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
2.2
11.4
98
460
L02
ICPC
Back symptom/complaint
1.5
11.4
341
2311
R12
ICD-10 Finland
Heartburn
1.6
11.3
291
1905
K08.80
ICD-10 Finland
Toothache NOS
1.6
11.3
290
1897
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.8
11.3
156
864
C03AA03
ATC
hydrochlorothiazide; oral
1.5
11.3
352
2403
A03
ICPC
Fever
1.4
11.3
509
3732
WZA90
NOMESCO Finland
Other medical or dental certificate
1.3
11.3
767
6013
M01AH01
ATC
celecoxib; oral
1.4
11.3
653
4996
C10AA05
ATC
atorvastatin; oral
1.3
11.2
1598
13797
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.8
11.2
164
925
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
1.9
11.2
138
737
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.4
11.2
486
3542
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
11.2
1499
12852
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.5
10.9
338
2306
K04.0
ICD-10 Finland
Pulpitis
1.6
10.9
256
1642
K07.60
ICD-10 Finland
Snapping jaw
1.8
10.9
166
949
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
10.9
638
4888
J01CA08
ATC
pivmecillinam; oral
1.3
10.9
1538
13257
M01AH02
ATC
rofecoxib; oral
1.4
10.8
467
3397
M77.1
ICD-10 Finland
Lateral epicondylitis
1.6
10.8
237
1494
RK420, ,
NOMESCO Finland
10.6
10.8
20
19
K80
ICPC
Cardiac arrhythmia NOS
1.5
10.7
321
2174
M54.3
ICD-10 Finland
Sciatica
1.7
10.7
211
1295
34609
ICD-8 Finland
Migraine, Unspecified
3.5
10.7
36
104
R03AC03
ATC
terbutaline; inhalant
1.4
10.7
476
3482
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.7
10.7
217
1343
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.6
10.6
249
1596
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
10.6
359
2494
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.4
10.6
424
3042
Z71.8
ICD-10 Finland
Other specified counselling
1.3
10.6
1160
9687
G04BD12
ATC
mirabegron; oral
1.4
10.6
467
3410
B37.0
ICD-10 Finland
Candidal stomatitis
3.0
10.6
46
156
RK320, ,
NOMESCO Finland
3.5
10.5
36
105
WZC00, ,
SPAT
1.4
10.5
501
3707
A03CA02
ATC
clidinium and psycholeptics; oral
1.6
10.5
216
1340
A01
ICPC
Pain general/multiple sites
1.5
10.5
373
2617
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.7
10.5
202
1233
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
10.4
788
6264
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
10.4
1547
13387
H80.8
ICD-10 Finland
Other otosclerosis
+∞
10.4
10
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
10.4
1021
8409
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.3
10.3
679
5290
7840A
ICD-9 Finland
Symptoms involving head and neck, Headache
3.1
10.3
41
132
SPAT1041
SPAT
Comprehensive hearing test
2.7
10.3
54
203
M54.2
ICD-10 Finland
Cervicalgia
1.6
10.2
274
1811
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
10.2
847
6818
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.5
10.2
360
2521
C05AA08
ATC
fluocortolone; rectal, topical
1.4
10.2
468
3440
K07.61
ICD-10 Finland
Cracking jaw joint
2.4
10.2
66
275
A04
ICPC
Weakness/tiredness general
1.4
10.1
567
4308
SGB10
NOMESCO Finland
Root filling of tooth with one root canal
1.4
10.1
387
2753
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
10.1
1336
11404
N01
ICPC
Headache
1.5
10.0
318
2180
SPAT1216
SPAT
Assessment of functional ability
1.4
10.0
582
4449
H83.3
ICD-10 Finland
Noise effects on inner ear
4.6
10.0
23
50
R60.9
ICD-10 Finland
Oedema, unspecified
1.6
9.9
212
1330
C07AB02
ATC
metoprolol; systemic
1.3
9.9
725
5737
D33.30
ICD-10 Finland
Acoustic neuroma
3.7
9.9
30
81
A01AB09
ATC
miconazole; local oral
1.5
9.8
300
2040
-1, ,
NOMESCO Finland
1.3
9.8
1021
8457
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.3
9.8
693
5452
C10AA01
ATC
simvastatin; oral
1.2
9.8
1555
13530
R51
ICD-10 Finland
Headache
1.7
9.8
173
1032
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.6
9.8
259
1708
R83
ICPC
Respiratory infection other
1.3
9.8
726
5753
TAB00
NOMESCO Finland
Lumbar puncture
1.8
9.8
142
801
SPAT1352
SPAT
Inspection, maintenance and instruction for use of hearing aid
2.5
9.8
58
232
R03AK07
ATC
formoterol and budesonide; inhalant
1.3
9.7
694
5467
R50.9
ICD-10 Finland
Fever, unspecified
1.4
9.7
499
3739
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
1.9
9.7
123
665
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
9.7
587
4514
H03AA01
ATC
levothyroxine sodium; systemic
1.3
9.7
858
6962
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.9
9.7
119
637
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
9.6
1348
11562
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
9.6
1283
10943
M01AC06
ATC
meloxicam; systemic, rectal
1.3
9.6
1308
11181
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.7
9.6
166
985
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
9.5
798
6425
R06AX22
ATC
ebastine; oral
1.4
9.5
564
4324
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.6
9.5
243
1591
UJF30
NOMESCO Finland
Ileoscopy through colon
1.4
9.5
371
2650
RK120, ,
NOMESCO Finland
7.1
9.5
22
31
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.5
9.5
294
2007
SPAT1104
SPAT
Monitoring of emergency patient
1.6
9.4
226
1457
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.4
9.4
481
3599
H80
ICD-10 Finland
Otosclerosis
100.3
9.4
10
*
H83.8
ICD-10 Finland
Other specified diseases of inner ear
100.3
9.4
10
*
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
9.4
3324
31558
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
3.1
9.3
38
124
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
2.5
9.3
57
231
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
3.2
9.3
36
114
RK110, ,
NOMESCO Finland
3.4
9.3
33
99
G04CA02
ATC
tamsulosin; oral
1.3
9.3
691
5475
D11
ICPC
Diarrhoea
1.4
9.3
373
2679
N05CF01
ATC
zopiclone; oral
1.3
9.2
1168
9892
M02AA07
ATC
piroxicam; topical
1.2
9.2
1307
11214
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.5
9.2
250
1659
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.8
9.1
130
729
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
9.1
441
3271
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.6
9.1
184
1139
A03FA02
ATC
cisapride; oral, rectal
1.5
9.1
268
1811
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.6
9.0
235
1544
M01AC01
ATC
piroxicam; systemic, rectal
1.4
9.0
461
3449
N03AX11
ATC
topiramate; oral
2.2
9.0
75
349
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
1.8
8.9
130
734
F41.09
ICD-10 Finland
UNS Panic Syndrome
2.1
8.9
77
363
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
8.9
857
7018
Z45.3
ICD-10 Finland
Adjustment and management of implanted hearing device
18.6
8.9
13
7
L15
ICPC
Knee symptom/complaint
1.3
8.9
909
7500
DFX03
NOMESCO Finland
Review, maintenance and user education for hearing aid
3.4
8.9
31
92
D09
ICPC
Nausea
1.8
8.9
138
795
N30.0
ICD-10 Finland
Acute cystitis
1.3
8.9
635
5002
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
8.8
1007
8418
S06.0
ICD-10 Finland
Concussion
1.4
8.8
348
2489
R03BA02
ATC
budesonide; inhalant
1.3
8.8
599
4681
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.4
8.8
369
2669
G03DB01
ATC
dydrogesterone; oral
1.4
8.8
389
2841
C01CA24
ATC
epinephrine; parenteral
1.6
8.8
189
1188
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
8.8
1396
12112
D01
ICPC
Abdominal pain/cramps general
1.4
8.8
399
2929
D02
ICPC
Abdominal pain epigastric
1.6
8.7
216
1404
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.3
8.7
941
7816
TQW40, ,
SPAT
1.4
8.7
347
2488
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
8.7
760
6148
EB1VA, ,
NOMESCO Finland
1.3
8.7
575
4477
L86
ICPC
Back syndrome with radiating pain
1.6
8.6
219
1431
L12
ICPC
Hand/finger symptom/complaint
1.3
8.6
574
4472
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.3
8.6
877
7229
N02CC03
ATC
zolmitriptan; nasal, oral
1.7
8.6
158
954
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
2.2
8.6
66
297
R03BC03
ATC
nedocromil; inhalant
1.5
8.6
229
1514
UDM02
NOMESCO Finland
Sinoscopy
2.1
8.6
77
369
DE2BM
NOMESCO Finland
Acoustic channel MRI examination with 3 Tesla magnet
16.3
8.5
13
8
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.4
8.5
486
3700
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.5
8.5
272
1869
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.4
8.5
328
2339
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.6
8.5
169
1043
R30.0
ICD-10 Finland
Dysuria
1.7
8.4
145
860
N06AB10
ATC
escitalopram; oral
1.3
8.4
611
4822
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
1.8
8.4
122
690
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
8.4
366
2668
Z00.0
ICD-10 Finland
General medical examination
1.3
8.3
640
5087
I84.1
ICD-10 Finland
Internal hemorrhoids with other complications
2.1
8.3
77
374
R03BA08
ATC
ciclesonide; inhalant
1.5
8.3
294
2062
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.5
8.2
276
1914
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.8
8.2
115
642
S01GX01
ATC
cromoglicic acid; ophthalmic
1.3
8.2
638
5076
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
2.0
8.2
81
402
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
8.2
851
7025
K59.09
ICD-10 Finland
Constipation, unspecified
1.5
8.2
249
1692
N80.0
ICD-10 Finland
Endometriosis of uterus
2.2
8.2
66
303
H02AB07
ATC
prednisone; oral
1.4
8.2
462
3512
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
1.7
8.2
138
815
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.5
8.2
285
1993
K03.64
ICD-10 Finland
Dental calculus supragingival
1.2
8.1
1017
8580
J01DA09
ATC
[U] cefadroxil
1.3
8.1
848
7006
R52.2
ICD-10 Finland
Other chronic pain
1.7
8.1
129
749
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
2.8
8.1
38
135
J05AB11
ATC
valaciclovir; oral
1.3
8.1
494
3799
U02
ICPC
Urinary frequency/urgency
1.3
8.1
538
4190
R06AX13
ATC
loratadine; oral
1.4
8.1
461
3509
M01AB08
ATC
etodolac; oral
1.5
8.0
244
1659
DE2DG
NOMESCO Finland
Acoustic channel very extensive MRI examination with high intensity magnet
8.9
8.0
16
18
SPAT1229
SPAT
Assessment of need for aid
1.5
8.0
277
1935
C01DA14
ATC
isosorbide mononitrate; oral
1.3
7.8
540
4227
R35
ICD-10 Finland
Polyuria
1.5
7.8
227
1530
M02AA10
ATC
ketoprofen; topical
1.3
7.8
552
4337
M79.7
ICD-10 Finland
Fibromyalgia
1.8
7.8
117
669
J01MA06
ATC
norfloxacin; oral
1.3
7.8
457
3495
N06AX16
ATC
venlafaxine; oral
1.4
7.8
439
3337
R06.5
ICD-10 Finland
Mouth breathing
1.5
7.8
265
1846
R52.9
ICD-10 Finland
Pain, unspecified
1.4
7.7
343
2506
M54.8
ICD-10 Finland
Other dorsalgia
1.7
7.7
149
912
C03BB04
ATC
chlortalidone and potassium; oral
45.1
7.7
9
*
4133
FHL
Stapedectomy sampling
45.1
7.7
9
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
7.7
690
5594
N06AB06
ATC
sertraline; oral
1.4
7.7
340
2484
M22.4
ICD-10 Finland
Chondromalacia patellae
2.0
7.7
83
427
D06
ICPC
Abdominal pain localized other
1.4
7.6
286
2027
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
2.9
7.6
35
123
A02BX02
ATC
sucralfate; oral
1.7
7.6
136
816
N03AF01
ATC
carbamazepine; oral, rectal
1.6
7.6
164
1033
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.3
7.6
871
7270
ZXC10
NOMESCO Finland
Use of laser
2.1
7.6
65
307
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.3
7.6
442
3377
G50.1
ICD-10 Finland
Atypical facial pain
2.1
7.5
66
315
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
1.8
7.5
112
640
ZXA10
NOMESCO Finland
Bilateral
1.3
7.5
634
5102
R01AD59
ATC
mometasone, combinations; nasal
1.6
7.5
185
1205
A02BA04
ATC
nizatidine; systemic
1.5
7.4
256
1786
GD1AA, ,
SPAT
1.3
7.4
473
3659
SFA00
NOMESCO Finland
Small restoration
1.3
7.4
453
3484
R13
ICD-10 Finland
Dysphagia
1.5
7.4
248
1721
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
7.4
679
5518
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
1.8
7.4
115
665
C01BC04
ATC
flecainide; systemic
1.7
7.3
118
688
D07AC01
ATC
betamethasone; topical
1.2
7.3
1258
10951
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.7
7.3
132
794
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
1.9
7.3
94
512
SPAT1081
SPAT
Cardiorespiratory global assessment
1.6
7.3
185
1210
C10AX09
ATC
ezetimibe; oral
1.3
7.3
584
4662
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
1.8
7.3
103
578
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.5
7.3
204
1364
38699, ,
ICD-8 Finland
+∞
7.3
7
*
SPAT1351
SPAT
Extensive ear examination
3.1
7.3
29
94
L57.0
ICD-10 Finland
Actinic keratosis
1.4
7.2
401
3040
K39
ICPC
Cardiovascular, Physical function test
4.3
7.2
18
42
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
7.2
615
4952
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.5
7.2
221
1508
WZB00, ,
SPAT
1.5
7.2
246
1715
F29
ICPC
Eye symptom/complaint other
1.4
7.2
346
2564
C10AA04
ATC
fluvastatin; oral
1.4
7.2
302
2187
A11
ICPC
Chest pain NOS
1.4
7.2
294
2119
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
4.5
7.2
17
38
S80.1
ICD-10 Finland
Contusion of other and unspecified parts of lower leg
1.8
7.2
107
611
M45
ICD-10 Finland
Ankylosing spondylitis
2.1
7.2
62
294
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.3
7.2
672
5475
OAA65, ,
SPAT
1.3
7.2
419
3202
S29
ICPC
Skin symptom/complaint other
1.3
7.1
705
5783
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
1.9
7.1
91
497
A05
ICPC
Feeling ill
1.6
7.0
160
1022
R06AE03
ATC
cyclizine; systemic, rectal
10.0
7.0
13
13
M54.1
ICD-10 Finland
Radiculopathy
1.7
7.0
132
805
WX290
NOMESCO Finland
Other blockage of nerve
1.2
7.0
1438
12730
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.2
6.9
1158
10043
K59.0
ICD-10 Finland
Constipation
1.5
6.9
188
1250
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.2
6.9
924
7833
D20
ICPC
Mouth/tongue/lip symptom/complaint
1.6
6.9
153
972
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.5
6.9
213
1456
H60.8
ICD-10 Finland
Other otitis externa
1.8
6.9
97
545
N05BA04
ATC
oxazepam; oral
1.2
6.9
900
7614
J01FA01
ATC
erythromycin; systemic
1.3
6.8
389
2959
D10
ICPC
Vomiting
1.6
6.8
139
864
R31
ICD-10 Finland
Unspecified haematuria
1.4
6.8
319
2352
J02AC02
ATC
itraconazole; systemic
1.3
6.8
579
4656
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.3
6.8
739
6121
H57.1
ICD-10 Finland
Ocular pain
1.7
6.8
120
720
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
1.5
6.7
183
1217
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
3.6
6.7
21
58
C03BA04
ATC
chlortalidone; oral
16.7
6.7
10
6
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
6.7
2271
20979
XKD00
NOMESCO Finland
Uroflowmetry
1.3
6.7
456
3560
H60
ICD-10 Finland
Otitis externa
1.6
6.7
154
987
A06AC51
ATC
ispaghula, combinations; oral
1.6
6.7
156
1003
N39.3
ICD-10 Finland
Stress incontinence
1.4
6.7
271
1951
R04
ICPC
Breathing problem other
1.6
6.7
129
792
E0000UV, ,
ATC
1.2
6.7
1431
12699
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.2
6.6
884
7487
N02CC07
ATC
frovatriptan; oral
1.8
6.6
102
588
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
1.6
6.6
133
824
J01FF01
ATC
clindamycin; systemic
1.2
6.6
890
7547
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
2.1
6.6
61
297
K29
ICPC
Cardiovascular sympt/complt other
1.6
6.6
153
982
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.5
6.6
195
1321
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.2
6.6
1236
10832
N63
ICD-10 Finland
Unspecified lump in breast
1.5
6.6
217
1504
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
1.4
6.6
291
2128
P20
ICPC
Memory disturbance
1.3
6.5
535
4282
D01BA02
ATC
terbinafine; oral
1.2
6.5
825
6947
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
2.5
6.5
38
152
R51.81
ICD-10 Finland
Facial pain NOS
1.9
6.5
80
431
G43
ICD-10 Finland
Migraine
1.7
6.5
119
721
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
6.5
879
7460
C03CA01
ATC
furosemide; systemic
1.2
6.5
1130
9833
RK290, ,
NOMESCO Finland
6.2
6.5
16
26
G44.0
ICD-10 Finland
Cluster headache syndrome
2.6
6.4
35
135
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.3
6.4
402
3101
C08CA05
ATC
nifedipine; systemic
1.5
6.4
194
1320
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.3
6.4
566
4572
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.4
6.4
40
165
R07.0
ICD-10 Finland
Pain in throat
1.5
6.4
196
1337
M01AX05
ATC
glucosamine; oral
1.2
6.4
722
6003
SDA03
NOMESCO Finland
Periodontal treatment
1.2
6.4
1304
11507
H91.0
ICD-10 Finland
Ototoxic hearing loss
14.3
6.4
10
7
C08DA01
ATC
verapamil; systemic
1.6
6.4
141
896
G43.8
ICD-10 Finland
Other migraine
2.3
6.3
45
197
XCK00
NOMESCO Finland
Perimetry
1.5
6.3
209
1450
P25
ICPC
Phase of life problem adult
1.7
6.3
114
689
E03.89
ICD-10 Finland
Other specified hypothyroidism
1.6
6.3
141
899
J05AB01
ATC
aciclovir; systemic
1.2
6.3
729
6082
207
Kela drug reimbursment
Chronic arrhythmias
1.3
6.3
569
4613
K04.1
ICD-10 Finland
Necrosis of pulp
1.4
6.2
318
2379
D12
ICPC
Constipation
1.6
6.2
128
800
K04
ICPC
Palpitations/awareness of heart
1.5
6.2
178
1200
D07AC13
ATC
mometasone; topical
1.2
6.2
942
8085
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
1.9
6.2
74
396
ZXA05
NOMESCO Finland
Left side
1.2
6.1
843
7161
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
1.8
6.1
91
521
C03DA01
ATC
spironolactone; oral
1.3
6.1
425
3330
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
6.1
832
7059
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
1.7
6.1
104
619
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
1.6
6.1
148
962
N06AX26
ATC
vortioxetine; oral
1.5
6.1
204
1419
C07AA07
ATC
sotalol; systemic
1.6
6.1
117
719
M50.3
ICD-10 Finland
Other cervical disc degeneration
1.8
6.1
77
420
H04
ICPC
Ear discharge
1.7
6.0
113
689
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.6
6.0
81
1401

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
3117
26603
1.78
48.23
5.4
4.5
11.79
13.23
mm/h
7.26
2941
24827
1618
11796
1.62
45.93
2.2
2.2
137.61
206.63
u/l
6.25
1522
11141
1839
14291
1.53
36.85
4.4
4.0
36.93
89.11
ng/l
1.00
1316
10446
1581
11921
1.54
36.22
2.6
2.7
57.64
66.95
u/l
0.74
1457
11034
2857
24600
1.57
34.32
5.6
4.9
1.91
2.60
—
5
33
2569
21779
1.50
31.68
4.7
5.0
6.60
6.74
mmol/l
3.27
2480
20751
3137
27949
1.57
29.00
8.6
8.6
77.14
80.52
u/l
4.63
2972
26519
2759
23991
1.48
27.94
5.6
5.1
1048.87
2407.27
e6/l
0.86
53
331
2129
17625
1.45
27.89
15.9
16.2
1.27
1.28
inr
0.27
1834
14673
3653
33969
1.88
27.34
19.5
17.5
22.48
24.83
mg/l
4.20
3122
28314
1654
13104
1.45
27.21
3.9
3.8
0.83
0.76
—
6
38
2338
19787
1.44
26.58
5.8
6.7
11.13
11.52
umol/l
1.10
2232
18888
3483
32073
1.67
25.35
6.6
5.7
1.95
1.95
mu/l
0.01
3260
29567
3729
35031
1.97
25.24
22.5
20.7
139.64
139.66
mmol/l
0.22
3680
34386
3733
35085
1.98
25.17
22.7
21.0
3.95
3.98
mmol/l
6.02
3680
34384
412
2413
1.79
24.90
2.5
2.4
23.63
22.44
au/ml
0.08
40
224
2296
19521
1.41
24.42
6.5
7.3
1.22
1.21
mmol/l
4.50
1982
16848
3055
27415
1.49
23.87
5.3
4.6
14.98
14.89
pmol/l
1.15
2812
25080
3512
32536
1.66
23.40
7.1
6.7
39.36
39.61
mmol/mol
1.07
3267
30286
2269
19365
1.40
22.89
4.6
4.2
2.79
3.84
estimate
0.14
445
4220
655
4438
1.57
22.50
2.3
2.3
111.03
139.90
ug/g
1.76
526
3511
3641
34116
1.76
22.49
6.7
6.1
2.66
2.68
mmol/l
0.55
3393
31560
3767
35670
1.98
22.45
14.0
12.9
24.90
25.07
u/l
0.29
3671
34613
2240
19117
1.39
22.35
4.6
4.2
0.00
0.00
estimate
1.08
430
4077
3559
33160
1.67
22.24
6.0
5.4
5.93
5.97
mmol/l
1.48
3293
30329
1504
12021
1.40
22.16
3.4
3.2
1237.24
1471.72
ng/l
0.86
1297
10448
2073
17480
1.39
22.16
5.7
6.6
1.22
1.21
mmol/l
3.39
1907
16128
1063
8002
1.45
21.85
1.3
1.3
1.17
1.57
u/ml
0.80
250
2118
373
2203
1.76
21.82
1.3
1.3
64.58
52.53
au/ml
0.33
19
159
2269
19498
1.38
21.16
4.6
4.2
0.06
0.34
estimate
0.53
432
3960
3789
36035
2.00
20.97
25.5
23.0
77.49
77.36
umol/l
0.10
3756
35600
2226
19108
1.37
20.67
6.6
6.5
0.19
0.19
e9/l
0.01
1965
16568
3557
33294
1.62
19.89
5.7
5.2
1.48
1.50
mmol/l
2.17
3295
30705
1837
15366
1.36
19.72
4.0
3.7
6.22
6.26
ph
1.02
1046
8495
3575
33516
1.63
19.71
5.8
5.3
4.59
4.64
mmol/l
1.77
3333
31129
2156
18500
1.36
19.58
6.5
6.3
0.58
0.59
e9/l
0.37
1884
15753
2160
18553
1.36
19.41
6.5
6.3
0.04
0.04
e9/l
0.37
1883
15804
787
5721
1.47
19.06
1.9
2.0
29.03
29.72
s
3.20
759
5564
3422
31809
1.53
19.05
4.8
4.4
1.28
1.28
mmol/l
0.18
3115
28993
1043
8001
1.41
18.82
1.9
1.8
1.14
1.31
mg/l
0.79
804
6254
2184
18882
1.35
18.31
6.5
6.4
1.94
1.89
e9/l
0.81
1951
16490
2548
22560
1.36
18.19
3.5
3.3
48.32
50.14
u/l
0.51
2379
21013
894
6767
1.41
17.17
1.4
1.3
31.12
32.12
iu/ml
0.08
265
2093
1707
14337
1.33
16.89
4.5
4.2
0.02
0.53
estimate
1.30
351
3324
842
6327
1.42
16.81
1.4
1.3
9.08
11.79
u/ml
0.66
313
2368
3809
36538
1.91
16.76
29.5
26.6
251.40
251.52
e9/l
0.04
3757
35790
717
5235
1.45
16.74
1.3
1.3
—
—
—
0
0
3810
36552
1.91
16.73
29.6
26.8
134.43
133.11
g/l
7.26
3780
36147
3809
36541
1.91
16.71
29.3
26.5
30.35
30.34
pg
0.26
3779
36123
3809
36541
1.91
16.71
29.4
26.5
91.24
91.43
fl
2.05
3779
36124
3809
36543
1.91
16.67
29.7
27.0
40.21
39.81
%
5.43
3779
36112
3809
36544
1.91
16.66
29.4
26.6
4.46
4.42
e12/l
5.02
3745
35666
3809
36546
1.91
16.62
29.5
26.6
6.77
6.75
e9/l
0.13
3745
35664
2366
20868
1.33
16.43
9.1
9.8
4.16
4.13
e9/l
0.23
2079
18056
1202
9617
1.36
16.33
2.7
2.8
337.34
342.62
umol/l
0.98
1058
8411
688
5012
1.45
16.21
1.4
1.4
531.70
530.18
titre
0.01
171
1147
425
2808
1.57
15.98
1.2
1.2
—
—
—
0
0
621
4451
1.47
15.90
5.4
5.1
33.21
33.16
%
0.04
434
2904
1976
17040
1.32
15.85
6.7
6.4
57.29
57.70
%
0.83
1874
16241
902
6939
1.39
15.54
1.5
1.5
2.31
2.49
g/l
2.04
536
4169
1975
17066
1.31
15.45
7.1
6.6
8.81
8.93
%
1.22
1852
15956
1969
17030
1.31
15.20
7.0
6.5
2.84
2.83
%
0.06
1845
15914
1971
17110
1.30
14.54
2.3
2.2
98.96
96.37
pmol/l
1.44
1022
8839
1963
17035
1.30
14.50
7.1
6.6
0.70
0.68
%
1.16
1839
15900
1929
16722
1.30
14.28
3.3
3.1
120.67
126.46
ug/l
0.36
1784
15522
1987
17309
1.29
14.10
4.6
5.1
35.86
35.29
g/l
5.13
1855
16211
941
7388
1.36
14.08
4.4
4.0
218.24
380.65
ng/l
1.46
729
5982
1994
17390
1.29
13.97
7.0
6.6
28.03
27.25
%
2.35
1891
16438
492
3501
1.46
12.93
2.2
2.3
378.67
382.80
nmol/l
0.17
455
3228
194
1106
1.79
12.79
1.3
1.2
37.60
43.30
u/ml
0.08
13
59
516
3716
1.45
12.72
4.1
4.4
7.36
7.36
ph
0.13
363
2667
1044
8483
1.31
12.04
4.9
4.5
1.02
1.19
kg/l
0.50
733
5725
440
3110
1.47
11.94
2.6
2.5
0.24
0.48
e6/l
3.25
422
2979
181
1042
1.77
11.57
1.3
1.3
2.79
5.66
u/ml
0.45
17
105
331
2221
1.53
11.56
1.3
1.3
219.52
203.29
u/ml
0.09
316
2042
1201
10034
1.28
11.02
3.9
3.6
0.06
0.23
estimate
0.82
344
3185
179
1044
1.75
10.95
1.3
1.3
6.03
8.37
u/ml
0.22
23
165
1442
12362
1.26
10.59
3.4
3.5
—
—
—
0
0
1938
17185
1.25
10.57
2.6
2.5
79.52
79.27
nmol/l
0.15
1752
15448
1699
14873
1.25
10.30
2.3
2.2
—
—
—
0
0
1274
10796
1.26
10.24
4.8
4.4
0.00
0.00
estimate
0.18
414
3766
1568
13612
1.25
10.22
3.1
3.6
2.36
2.36
mmol/l
0.24
1400
12301
605
4643
1.36
10.15
2.7
3.4
4.65
4.57
e9/l
0.06
503
3992
96
470
2.07
10.04
1.3
1.3
—
—
—
0
0
277
1855
1.53
9.77
2.1
2.0
—
—
—
0
0
1209
10235
1.26
9.69
2.6
2.4
2.78
2.91
mg/l
1.44
1054
8817
1316
11270
1.25
9.49
1.7
1.7
20.22
20.46
nmol/l
0.21
1122
9502
236
1542
1.56
9.30
2.0
1.7
5.97
6.34
iu/ml
0.10
57
363
388
2808
1.42
9.23
3.1
2.9
10.14
10.65
g/l
1.40
363
2589
1380
11924
1.24
9.09
3.9
4.3
7.40
7.40
ph
0.09
984
8608
1683
14859
1.23
9.03
2.0
1.9
1.36
1.34
mmol/l
0.47
1402
12351
184
1155
1.62
8.61
1.7
1.7
—
—
—
0
0
2694
25027
1.23
8.61
4.7
4.3
0.50
7229.07
—
6
57
488
3733
1.35
8.29
2.3
2.2
0.00
0.01
estimate
1.06
82
751
1407
12340
1.22
7.70
3.6
3.5
59.46
77.86
e6/l
0.48
1103
9418
543
4269
1.31
7.62
1.3
1.4
—
—
—
0
0
1177
10154
1.23
7.55
3.3
3.2
0.20
0.05
0.45
20
303
824
6852
1.26
7.40
1.7
1.8
1121.84
1175.94
nmol/l
1.00
645
5193
348
2569
1.39
7.39
1.3
1.3
—
—
—
0
0
102
574
1.80
7.17
1.4
1.3
0.15
0.34
nmol/l
—
6
34
1565
13939
1.20
7.14
4.3
4.1
72.28
110.19
e6/l
1.73
1156
9860
1069
9196
1.22
6.95
6.1
5.8
3.58
3.49
ug/l
0.03
985
8252
90
493
1.84
6.92
1.3
1.3
0.19
0.22
nmol/l
0.49
75
393
85
461
1.86
6.75
2.7
2.2
25.00
22.53
mg/l
0.18
39
168
550
4405
1.29
6.69
2.5
2.7
8.80
8.37
umol/l
0.14
484
3856
1879
17089
1.19
6.62
2.7
2.8
—
—
estimate
—
0
0
260
1866
1.42
6.52
2.4
2.2
0.00
0.44
estimate
0.51
62
583
137
860
1.61
6.49
1.1
1.1
4.93
7.05
eliau/ml
—
6
92
130
806
1.63
6.48
1.2
1.2
49.17
45.86
u/ml
0.05
12
85
322
2404
1.37
6.40
3.3
3.8
7.42
7.42
ph
1.92
268
2009
997
8579
1.22
6.38
2.8
2.7
4.26
5.95
e6/l
6.87
906
7832
280
2052
1.39
6.23
2.5
2.4
—
—
—
0
0
207
1438
1.46
6.19
1.3
1.2
1.22
1.46
u/ml
0.09
23
112
47
214
2.21
6.06
1.1
1.1
0.29
8.80
nmol/l
—
8
48
436
3434
1.30
6.02
2.8
2.8
65.92
66.30
g/l
0.51
403
3149
83
465
1.80
5.99
1.4
1.3
—
—
nmol/l
—
0
0
306
2301
1.36
5.82
3.4
3.5
4.41
4.43
pmol/l
0.21
275
2052
238
1718
1.41
5.80
1.3
1.2
—
—
—
0
0
324
2473
1.34
5.60
3.3
3.8
5.11
5.17
kpa
0.62
308
2370
69
382
1.82
5.22
4.1
4.3
—
—
—
0
0
402
3203
1.28
5.09
3.2
3.1
197.30
212.10
ng/l
0.27
379
2937
44
211
2.10
5.04
1.2
1.6
5.08
7.01
u/l
1.33
37
184
47
232
2.04
5.00
1.1
1.1
261.01
280.74
mg/l
0.34
42
200
48
240
2.01
4.93
1.2
1.1
33.75
42.51
mg/l
0.97
43
203
1382
12484
1.16
4.80
3.5
3.4
32.94
44.44
mg/l
1.67
821
7842
171
1206
1.44
4.80
1.4
1.4
292.30
272.63
ug/g
0.51
101
714
46
229
2.02
4.79
1.9
1.8
17.38
17.22
nmol/l
0.05
46
211
224
1656
1.37
4.79
3.4
3.9
—
—
—
0
0
396
3175
1.27
4.77
3.0
3.7
76.58
90.77
ng/l
4.02
337
2707
179
1277
1.42
4.72
3.7
3.9
24.98
24.97
mmol/l
0.03
165
1167
1425
12917
1.16
4.71
3.5
3.4
7.09
7.05
mmol/l
0.14
1185
10872
72
418
1.74
4.69
1.5
1.4
31.55
32.82
u/l
0.11
58
348
185
1330
1.41
4.68
1.3
1.3
—
—
—
0
0
184
1325
1.41
4.61
1.6
1.6
24.77
18.79
u/ml
0.17
32
282
155
1082
1.45
4.61
2.2
1.6
0.24
0.24
g/l
0.01
150
1031
107
694
1.56
4.53
1.5
1.3
11.93
12.31
u/l
0.11
91
563
12
23
5.23
4.45
1.8
1.7
14.75
29.21
pmol/l
0.52
12
18
1332
12054
1.16
4.44
3.2
3.2
29.99
36.32
u/l
3.53
1242
11344
21
76
2.77
4.44
1.0
1.1
—
—
—
0
0
529
4425
1.23
4.38
1.6
1.5
—
—
—
0
0
1395
12698
1.15
4.25
4.3
4.1
6.28
8.38
mg/mmol
1.15
799
7771
285
2231
1.30
4.17
2.1
2.0
1.13
1.40
g/l
2.21
262
2045
156
1113
1.42
4.16
2.1
1.6
1.19
1.18
g/l
0.15
151
1063
769
6699
1.18
4.12
2.4
2.6
13.28
12.58
umol/l
1.92
715
6224
1193
10763
1.15
4.08
4.2
4.4
—
—
—
0
0
401
3283
1.25
4.07
3.8
4.3
0.60
0.71
%
0.42
132
999
48
259
1.86
4.02
2.1
1.7
385.55
309.33
mu/l
0.71
42
208
894
7912
1.17
3.93
4.9
4.8
—
—
—
0
0
92
599
1.55
3.88
1.9
1.6
0.71
0.81
g/l
0.59
72
455
435
3612
1.23
3.88
2.4
2.5
67.94
69.88
e9/l
0.55
343
2626
158
1145
1.40
3.87
4.8
6.7
1.37
1.31
mmol/l
0.29
141
1013
1032
9249
1.16
3.83
2.3
2.4
—
—
—
0
0
210
1599
1.33
3.77
1.1
1.1
52.00
140.15
titre
—
5
41
366
2999
1.24
3.70
3.1
2.9
6.10
6.08
ph
0.18
247
2075
393
3254
1.23
3.61
2.5
2.4
6.44
6.89
ug/l
0.18
339
2856
292
2339
1.27
3.60
1.2
1.2
124.88
144.59
u/ml
0.35
118
853
397
3297
1.23
3.55
4.0
4.5
0.09
0.12
%
0.39
116
909
541
4633
1.19
3.52
2.6
2.5
1.77
1.82
%
0.54
492
4110
237
1855
1.30
3.51
1.3
1.3
—
—
—
0
0
829
7355
1.16
3.50
3.0
3.0
508.69
520.54
mosm/kgh2o
0.76
717
6458
904
8072
1.15
3.50
2.8
3.1
2.45
2.46
mmol/l
1.06
796
7235
744
6552
1.17
3.46
3.1
3.3
0.82
0.81
mmol/l
0.55
680
6155
143
1042
1.39
3.43
1.1
1.1
—
—
—
0
0
35
180
1.95
3.42
1.2
1.2
0.57
0.54
ratio
0.17
26
104
123
874
1.42
3.42
1.7
1.6
—
—
—
0
0
1322
12136
1.13
3.38
2.4
2.5
—
—
—
0
0
410
3445
1.21
3.27
4.0
4.4
0.82
0.88
%
0.21
131
1054
1174
10715
1.14
3.27
3.4
3.3
0.40
0.46
e6/l
0.42
887
7915
135
985
1.38
3.24
1.1
1.1
—
—
—
0
0
181
1389
1.32
3.13
2.8
2.6
—
—
—
0
0
18
73
2.47
3.12
1.9
2.0
—
—
—
0
0
301
2464
1.24
3.10
5.9
6.8
24.81
24.58
mmol/l
0.57
286
2362
109
775
1.42
3.05
1.2
1.4
11.99
37.09
e6/l
1.35
89
566
71
463
1.54
3.05
1.4
1.3
88.72
62.97
u/ml
—
8
24
81
544
1.50
3.04
1.4
1.4
72.89
63.65
mu/l
0.17
73
485
905
8169
1.14
2.96
1.7
1.7
535.87
32949783.67
pmol/l
6.69
752
6771
110
790
1.40
2.93
1.3
1.4
1364.28
1290.52
e6/l
0.03
93
617
19
83
2.30
2.83
1.2
1.1
248.43
321.08
pmol/l
0.64
14
63
584
5138
1.16
2.75
4.3
5.8
1.01
1.04
mmol/l
2.23
540
4760
11
34
3.24
2.72
1.3
1.3
3.75
5.72
mmol/l
—
6
18
109
793
1.39
2.72
5.9
7.9
105.14
104.97
mmol/l
0.16
100
709
109
793
1.39
2.72
5.9
7.9
11.13
11.17
mmol/l
0.05
100
708
6
10
6.01
2.70
1.0
1.1
5.73
4.56
mmol/l
—
6
5
180
1414
1.29
2.67
1.4
1.4
28.98
32.02
iu/l
0.65
153
1227
97
694
1.41
2.67
2.1
1.9
5330.95
5239.22
u/l
0.01
29
281
59
382
1.55
2.66
2.2
2.1
—
—
—
0
0
259
2132
1.23
2.58
2.3
2.3
12.39
12.62
nmol/l
0.16
238
1906
49
306
1.61
2.58
1.2
1.2
—
—
—
0
0
223
1807
1.25
2.57
4.7
5.3
1.57
1.58
%
0.02
210
1711
204
1638
1.26
2.55
2.0
2.0
2.26
2.39
ug/l
0.06
173
1457
127
960
1.33
2.51
1.9
2.0
13.78
12.00
mg/l
0.21
118
887
38
224
1.70
2.50
1.7
1.6
—
—
—
0
0
96
695
1.39
2.49
1.2
1.3
34.41
31.27
u/l
0.09
83
595
50
317
1.58
2.49
1.1
1.1
—
—
—
0
0
210
1700
1.25
2.45
1.9
2.5
4.29
4.22
g/l
0.66
191
1551
210
1701
1.25
2.44
1.9
2.5
7.44
7.45
g/l
0.04
191
1552
43
264
1.64
2.44
1.1
1.1
—
—
—
0
0
494
4332
1.16
2.44
1.8
1.8
—
—
—
0
0
34
196
1.74
2.42
2.5
2.3
590.21
512.06
e6/l
0.31
28
159
695
6247
1.14
2.41
2.3
2.6
2.38
2.31
g/l
2.96
643
5758
20
97
2.07
2.37
2.3
1.7
—
2.00
—
0
5
209
1699
1.24
2.36
1.9
2.5
3.66
3.71
g/l
0.17
190
1552
98
719
1.37
2.36
1.2
1.3
—
—
—
0
0
643
5761
1.14
2.34
2.4
2.7
22.46
21.92
%
0.42
597
5342
16
71
2.26
2.34
1.1
1.1
0.02
2.03
u/ml
—
9
31
177
1414
1.26
2.33
3.0
3.6
44.14
61.95
mg/l
0.59
159
1212
177
1415
1.26
2.32
3.0
3.6
41.15
91.87
mg/l
0.73
160
1215
55
364
1.52
2.29
1.5
1.4
2.53
2.89
g/l
0.96
40
261
55
364
1.52
2.29
1.5
1.4
0.42
0.40
g/l
0.15
42
261
55
364
1.52
2.29
1.5
1.4
6.64
6.88
g/l
0.22
40
260
94
692
1.37
2.24
1.9
1.9
5.41
4.80
mmol/24h
0.78
84
601
383
3317
1.17
2.23
4.2
4.7
0.48
0.29
%
0.16
98
860
488
4315
1.15
2.17
3.5
4.2
10.82
24.83
ug/l
1.37
390
3537
37
227
1.64
2.14
1.1
1.1
—
—
—
0
0
44
283
1.56
2.11
1.2
1.2
—
—
—
0
0
203
1669
1.23
2.10
5.0
5.6
0.93
0.87
%
1.55
191
1577
168
1353
1.25
2.10
2.2
3.1
25.04
24.97
mmol/l
0.10
163
1336
2855
27737
1.10
2.09
24.6
22.7
332.19
331.19
g/l
7.72
2850
27577
195
1599
1.23
2.07
1.8
2.6
2.80
2.94
g/l
1.26
176
1451
1203
11243
1.10
2.05
5.8
6.5
—
—
—
0
0
121
945
1.29
1.96
2.3
2.3
137.60
127.46
g/l
4.01
88
741
130
1029
1.27
1.91
2.1
2.0
3.23
9.83
iu/l
0.61
44
408
66
474
1.40
1.87
1.4
1.5
33.28
27.98
ng/l
0.29
66
474
65
466
1.40
1.86
1.0
1.1
4.09
3.11
u/ml
0.32
30
233
16
79
2.03
1.85
1.0
1.1
2.27
12.67
u/ml
—
8
52
16
79
2.03
1.85
1.0
1.1
0.77
0.70
umol/24h
—
6
37
39
253
1.55
1.84
1.2
1.3
0.09
1.40
u/ml
1.58
23
146
174
1431
1.23
1.83
1.1
1.1
—
—
—
0
0
60
426
1.41
1.82
2.1
2.0
—
—
—
0
0
39
254
1.54
1.81
1.5
1.7
86.49
107.38
ng/l
1.39
39
254
59
419
1.41
1.79
3.9
3.7
51.60
57.81
%
1.27
50
361
21
116
1.81
1.78
1.0
1.0
—
—
—
0
0
76
565
1.35
1.77
1.2
1.1
1.90
1.74
u/ml
0.05
42
315
52
362
1.44
1.76
1.5
1.4
—
—
—
0
0
6
18
3.34
1.74
1.5
2.2
213.67
194.89
ng/l
—
6
18
731
6724
1.11
1.71
3.2
3.0
1.08
1.16
e6/l
0.23
430
3615
601
5477
1.11
1.67
3.3
3.3
0.80
0.78
ug/l
0.12
395
3721
19
329
0.58
1.64
1.2
1.5
—
—
—
0
0
1011
9468
1.09
1.62
3.9
4.1
89.92
89.19
%
0.42
990
9248
41
278
1.48
1.61
1.0
1.0
281.85
321.41
ng/l
0.54
33
182
41
278
1.48
1.61
1.0
1.0
773.68
734.93
ng/l
0.21
31
178
50
354
1.42
1.58
1.1
1.1
3.74
3.39
u/ml
0.05
21
151
13
64
2.03
1.54
4.5
2.8
—
—
—
0
0
214
1835
1.18
1.49
3.3
3.2
25.61
25.31
mmol/l
0.62
206
1769
19
319
0.59
1.48
1.2
1.5
—
—
—
0
0
174
1469
1.19
1.46
1.9
2.5
10.12
10.37
g/l
0.32
154
1307
18
102
1.77
1.44
1.2
1.3
36.25
38.62
g/l
—
10
48
19
316
0.60
1.44
1.2
1.5
1.21
1.30
mm
0.40
12
214
6
22
2.73
1.43
1.5
1.8
—
—
—
0
0
126
1033
1.23
1.43
1.2
1.2
182.50
93.41
titre
0.53
16
88
52
379
1.38
1.42
1.1
1.1
4.42
2.46
u/ml
0.25
24
183
12
225
0.53
1.39
1.0
1.1
—
—
—
0
0
23
142
1.62
1.38
1.2
1.1
1149.24
384.66
ng/l
—
8
38
190
2209
0.85
1.36
1.7
1.8
3.50
3.47
mmol/l
0.09
122
1557
267
3027
0.87
1.36
2.1
2.0
3.47
3.39
ratio
0.52
198
2367
0
38
0.00
1.34
0.0
1.4
—
—
—
0
0
0
39
0.00
1.33
0.0
1.2
—
1.14
—
0
7
505
4629
1.10
1.29
5.0
7.5
1.15
1.03
mmol/l
0.26
411
3810
34
485
0.70
1.29
3.7
5.2
379.41
352.79
umol/l
0.52
28
431
27
178
1.52
1.26
1.3
1.7
3.94
1.93
u/field
0.58
18
126
152
1289
1.19
1.25
3.3
3.2
274.70
395.90
mg/l
0.84
53
522
405
3679
1.11
1.24
2.3
2.4
37.01
40.40
u/l
0.39
339
3085
507
4660
1.10
1.24
5.1
7.6
12.38
12.25
kpa
0.19
481
4479
25
163
1.54
1.22
1.2
1.3
134.16
155.77
mmol/24h
0.84
25
163
11
57
1.93
1.17
1.2
1.0
—
—
—
0
0
30
207
1.45
1.15
1.2
1.1
—
—
—
0
0
30
207
1.45
1.15
2.0
1.6
—
—
—
0
0
256
2278
1.13
1.13
1.5
1.4
—
—
—
0
0
505
4663
1.10
1.13
5.1
7.6
5.04
5.11
kpa
0.80
480
4481
58
449
1.30
1.12
1.3
1.2
—
—
—
0
0
11
58
1.90
1.12
1.6
1.6
2.65
2.64
mmol/l
0.00
11
48
504
4658
1.09
1.11
5.1
7.6
7.43
7.41
ph
2.28
301
2554
654
6114
1.08
1.10
3.3
3.1
3.84
2.95
e6/l
0.88
355
2992
441
4053
1.10
1.10
3.0
3.6
7.39
7.38
ph
2.11
248
2334
56
433
1.30
1.09
1.1
1.1
0.81
1.21
u/ml
0.30
29
221
98
810
1.22
1.09
2.9
2.7
17.58
16.10
%
4.00
93
796
80
647
1.24
1.09
4.5
3.8
1.64
1.65
%
0.00
70
581
108
902
1.20
1.08
3.2
3.4
0.82
0.81
nmol/l
0.05
92
727
53
409
1.30
1.06
2.8
2.7
—
—
—
0
0
36
262
1.38
1.05
1.3
1.8
14.16
8.73
umol/l
0.20
23
192
73
588
1.25
1.04
1.1
1.1
—
—
—
0
0
49
375
1.31
1.04
2.8
2.5
—
—
—
0
0
51
393
1.30
1.03
1.1
1.3
—
—
—
0
0
5
22
2.27
1.03
1.4
1.0
—
—
—
0
0
7
34
2.06
1.02
1.0
1.2
0.05
0.03
u/ml
—
7
34
17
106
1.61
1.02
1.5
1.2
—
—
—
0
0
23
156
1.48
0.98
4.3
4.0
—
—
—
0
0
9
158
0.57
0.98
12.4
13.4
701.00
8985.99
nmol/l
—
9
153
5
23
2.18
0.98
2.8
1.5
326.40
310.48
umol/24h
—
5
23
58
459
1.27
0.97
1.0
1.1
0.77
1.14
u/ml
0.43
25
190
151
1314
1.16
0.96
1.9
2.0
21.32
21.01
s
0.17
133
1157
26
182
1.43
0.95
1.0
1.0
—
—
—
0
0
277
2508
1.11
0.95
3.0
3.0
128.82
127.76
g/l
0.39
266
2433
14
85
1.65
0.94
1.1
1.3
2.27
1.58
mmol/l
—
7
57
48
374
1.29
0.92
1.2
1.3
7.76
7.56
mmol/l
0.18
41
320
35
464
0.75
0.91
1.1
1.2
—
—
—
0
0
574
5389
1.08
0.89
1.9
2.0
—
—
—
0
0
100
850
1.18
0.87
2.0
1.7
298.13
302.95
mu/l
0.05
91
783
287
2618
1.10
0.87
1.4
1.4
—
—
—
0
0
24
169
1.42
0.87
1.8
1.7
39.73
39.68
g/l
0.01
24
169
92
779
1.19
0.85
3.3
4.5
2.18
2.71
mmol/l
1.42
54
539
54
668
0.81
0.84
1.3
1.6
1436.58
1026.88
mu/l
0.42
42
531
64
524
1.22
0.83
2.6
2.6
—
—
—
0
0
54
434
1.25
0.83
6.4
5.6
8.57
7.44
mmol/l
0.49
48
371
97
827
1.18
0.83
1.3
1.4
62.17
60.35
mmol/l
0.18
78
675
6
32
1.88
0.81
1.2
1.2
—
—
—
0
0
6
32
1.88
0.81
1.2
1.2
—
—
—
0
0
6
32
1.88
0.81
1.2
1.1
6.13
6.03
mmol/l
—
6
32
16
237
0.67
0.81
1.4
2.2
7.78
8.52
mmol/l
0.34
16
237
122
1062
1.15
0.81
2.7
3.6
4.94
1.98
index
0.84
71
538
49
391
1.26
0.81
2.8
3.5
11.93
13.03
index
0.40
30
212
50
401
1.25
0.79
1.6
1.2
—
—
—
0
0
9
148
0.61
0.79
3.6
2.2
296.11
916.62
e6/l
—
9
103
101
869
1.17
0.78
3.2
4.0
—
—
—
0
0
55
447
1.23
0.78
1.1
1.3
—
—
—
0
0
1650
16054
1.05
0.76
12.6
12.1
0.00
0.00
e9/l
1.42
1387
13056
53
431
1.23
0.75
1.4
1.5
51.17
59.97
%
0.72
30
261
32
244
1.31
0.75
1.1
1.1
12.77
9.48
iu/ml
—
6
70
89
762
1.17
0.74
3.8
3.5
27.02
28.35
mg/l
0.13
62
525
5
24
2.08
0.74
1.0
1.4
—
—
—
0
0
35
271
1.29
0.74
1.2
1.2
—
—
—
0
0
7
38
1.84
0.73
1.0
1.2
1.46
1.76
umol/24h
—
7
38
43
343
1.26
0.73
1.2
1.3
—
—
—
0
0
26
193
1.35
0.73
1.2
1.1
19.05
16.11
u/ml
—
10
81
206
1871
1.11
0.72
1.6
1.7
1.63
1.55
g/l
0.53
178
1608
143
1273
1.13
0.71
3.0
3.4
3.85
3.35
ratio
0.07
83
754
538
5088
1.07
0.71
1.3
1.3
—
—
—
0
0
21
151
1.39
0.71
5.1
5.2
70.91
61.85
mg/l
0.40
11
108
42
336
1.25
0.70
1.8
1.9
3.39
4.37
mg/l
1.62
42
326
26
195
1.34
0.69
1.2
1.2
132.31
132.98
nmol/l
0.02
26
195
115
1012
1.14
0.69
1.3
1.2
—
—
—
0
0
10
157
0.64
0.68
6.9
13.2
0.54
0.64
mmol/l
—
10
142
63
529
1.19
0.67
1.1
1.1
19.24
22.56
au/ml
0.13
15
107
117
1033
1.14
0.67
1.4
1.2
220.00
891.38
titre
—
6
29
25
328
0.76
0.66
1.1
1.1
—
—
—
0
0
17
237
0.72
0.66
1.8
2.5
16.09
16.10
%
0.00
17
237
97
847
1.15
0.65
1.2
1.2
—
—
—
0
0
72
841
0.85
0.65
2.3
2.3
77.66
98.39
ug/min
0.21
46
495
51
422
1.21
0.64
1.1
1.1
1.89
3.81
eliau/ml
0.98
15
170
5
29
1.73
0.64
1.0
1.2
—
—
—
0
0
23
172
1.34
0.63
4.3
3.8
—
—
—
0
0
413
3892
1.07
0.62
3.0
3.6
1.71
1.87
mmol/l
0.46
374
3401
54
643
0.84
0.62
1.3
1.4
—
—
—
0
0
43
351
1.23
0.62
4.3
5.6
15.35
67.04
u/ml
1.89
11
109
49
588
0.83
0.61
1.1
1.2
278.63
282.58
u/ml
0.03
24
361
425
4012
1.07
0.61
2.9
3.5
5.75
5.84
kpa
1.20
416
3904
8
50
1.60
0.61
1.1
1.0
—
—
—
0
0
8
50
1.60
0.61
1.4
1.4
—
—
—
0
0
375
3526
1.07
0.61
5.5
7.1
9.49
10.34
mmol/l
1.69
351
3380
126
1127
1.12
0.61
9.0
11.1
—
—
—
0
0
0
20
0.00
0.60
0.0
9.9
—
141.33
—
0
15
317
3387
0.93
0.60
5.1
8.5
—
—
—
0
0
8
51
1.57
0.60
1.1
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
3.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
40
326
1.23
0.59
1.1
1.1
0.64
0.22
u/ml
0.30
15
113
16
114
1.41
0.58
1.4
1.3
1894.24
395.18
ug/l
—
9
51
70
604
1.16
0.57
1.1
1.1
—
—
—
0
0
6
35
1.72
0.57
1.2
1.0
—
—
—
0
0
6
35
1.72
0.57
3.0
3.0
—
—
—
0
0
14
98
1.43
0.56
1.4
1.3
36.25
34.56
%
—
8
64
5
89
0.56
0.56
1.0
1.4
—
0.32
—
0
18
152
1383
1.10
0.55
1.7
2.2
218.07
700.10
ug/l
2.32
141
1307
6
37
1.62
0.55
1.2
2.6
0.67
0.84
u/field
—
6
37
32
394
0.81
0.54
1.2
1.5
53.00
60.67
ug/l
0.50
27
317
11
74
1.49
0.53
3.8
2.8
—
—
—
0
0
20
152
1.32
0.52
2.9
2.2
270.25
130.00
umol/l
—
8
87
12
83
1.45
0.51
2.0
2.4
—
—
—
0
0
406
3855
1.06
0.51
5.7
8.3
123.59
120.06
g/l
3.18
395
3769
15
109
1.38
0.50
1.2
1.0
—
—
—
0
0
15
109
1.38
0.50
1.2
1.0
—
—
—
0
0
15
109
1.38
0.50
1.2
1.0
—
—
—
0
0
118
1302
0.90
0.49
1.7
1.6
0.34
0.34
mg/l
0.01
54
571
78
689
1.13
0.49
1.3
1.6
—
—
—
0
0
41
344
1.19
0.48
1.4
1.5
—
—
—
0
0
307
2898
1.06
0.48
4.7
4.2
—
—
—
0
0
2826
27962
1.04
0.47
23.3
21.6
13.69
13.75
%
1.64
2804
27570
41
345
1.19
0.47
1.1
1.2
—
—
—
0
0
7
47
1.49
0.47
1.7
1.4
3.63
700006.51
nmol/l
—
7
38
18
137
1.32
0.47
3.3
2.1
19.09
20.40
ug/l
0.16
18
124
433
4133
1.05
0.46
5.2
7.9
95.18
95.51
%
0.35
414
3989
62
544
1.14
0.44
1.3
1.9
—
—
—
0
0
59
516
1.15
0.44
1.7
1.8
—
—
—
0
0
10
69
1.45
0.44
1.3
1.1
—
—
—
0
0
16
121
1.32
0.44
1.3
1.4
3.27
3.15
mmol/l
0.07
16
111
63
554
1.14
0.44
5.2
6.5
11.66
12.38
mg/l
0.62
58
520
252
2373
1.07
0.43
1.3
1.4
—
—
—
0
0
32
266
1.20
0.43
1.7
1.4
33.33
73.16
titre
—
6
19
29
239
1.21
0.42
5.1
7.0
16.84
97.54
ug/l
0.54
19
144
28
230
1.22
0.42
1.1
1.2
—
—
—
0
0
90
812
1.11
0.42
1.3
1.3
157.38
215.10
miu/ml
1.04
35
350
5
32
1.56
0.42
1.0
1.0
2.52
6.84
u/ml
—
5
32
87
784
1.11
0.42
3.7
3.4
56.36
58.26
%
0.67
87
784
10
70
1.43
0.41
1.3
1.4
—
—
—
0
0
55
482
1.14
0.41
2.1
2.2
1.12
1.21
g/24h
0.08
29
278
351
3347
1.05
0.41
2.9
3.0
4.42
4.50
kpa
0.41
345
3252
5
34
1.47
0.40
13.6
13.1
0.22
0.18
%
—
5
34
19
150
1.27
0.40
1.7
2.0
73.19
56.68
ug/l
0.30
19
145
0
18
0.00
0.40
0.0
1.3
—
0.17
—
0
18
33
278
1.19
0.40
1.2
1.0
283.24
292.09
mg/l
0.37
33
253
40
343
1.17
0.39
1.1
1.1
—
—
—
0
0
7
104
0.67
0.39
1.0
1.1
—
—
—
0
0
108
989
1.09
0.39
1.5
1.6
10111.32
12663.46
e6/l
0.29
80
683
65
579
1.12
0.39
2.3
2.1
0.89
0.91
%
0.13
44
396
51
447
1.14
0.38
1.3
1.4
85248.94
72467.26
e6/l
0.10
31
249
5
36
1.39
0.38
1.0
1.3
—
640.53
—
0
9
54
477
1.13
0.37
1.8
1.8
—
—
—
0
0
50
565
0.88
0.35
1.3
1.4
177.83
152.90
au/ml
—
6
159
34
292
1.17
0.34
1.1
1.1
30.91
35.05
mmol/l
0.56
29
254
57
509
1.12
0.34
1.3
1.5
2029.02
3868.97
e6/l
0.52
45
361
211
1997
1.06
0.34
4.2
3.6
1.02
1.02
ratio
0.52
192
1799
228
2402
0.95
0.34
5.1
9.1
24.45
24.33
mmol/l
0.23
219
2354
48
424
1.13
0.34
1.3
1.5
—
—
—
0
0
17
136
1.25
0.33
1.2
1.1
—
—
—
0
0
19
155
1.23
0.32
1.3
1.5
2.35
2.01
umol/l
1.09
19
140
6
47
1.28
0.32
1.7
1.1
—
—
—
0
0
6
47
1.28
0.32
1.7
1.1
—
—
—
0
0
6
47
1.28
0.32
1.7
1.1
—
—
—
0
0
27
229
1.18
0.32
1.4
1.5
76.89
81.69
umol/l
0.39
27
229
17
137
1.24
0.32
1.1
1.2
17.00
10.56
mm/h
0.63
17
137
36
314
1.15
0.31
1.4
2.0
3.50
1.55
u/field
0.57
18
168
19
156
1.22
0.31
1.3
1.5
34.63
30.17
umol/l
1.01
19
145
188
1983
0.95
0.30
1.6
1.6
—
—
—
0
0
14
111
1.26
0.30
1.5
1.4
8.47
6.90
mmol/l
0.51
14
111
7
55
1.27
0.30
1.6
1.3
—
—
—
0
0
42
372
1.13
0.30
2.2
2.3
—
—
—
0
0
101
938
1.08
0.29
5.8
4.5
—
—
—
0
0
18
148
1.22
0.29
1.3
1.4
176.73
213.15
pmol/l
0.22
18
148
26
223
1.17
0.28
1.5
1.7
2.48
4.36
ug/l
0.68
19
177
396
3831
1.04
0.28
2.0
2.2
0.22
0.21
g/l
1.93
367
3576
10
76
1.32
0.28
3.0
2.0
0.12
0.14
e9/l
—
5
35
8
64
1.25
0.27
1.3
1.4
—
—
—
0
0
24
279
0.86
0.27
1.1
1.2
—
113.75
—
0
8
29
253
1.15
0.26
1.2
1.3
—
—
—
0
0
47
424
1.11
0.26
1.7
1.5
0.26
0.32
nmol/l
0.55
31
310
20
235
0.85
0.25
1.5
1.4
7.40
7.40
ph
0.06
15
162
361
3495
1.04
0.25
1.4
1.4
—
—
—
0
0
10
127
0.79
0.25
3.4
1.9
—
—
—
0
0
234
2246
1.04
0.25
6.8
10.2
16.10
15.81
%
0.76
222
2172
9
75
1.20
0.25
1.1
1.1
—
14.60
u/ml
—
0
5
114
1074
1.06
0.24
2.2
2.9
1.48
1.62
mg/l
1.39
104
961
22
189
1.16
0.24
1.6
1.8
1.89
7.87
nmol/l
1.52
17
156
6
82
0.73
0.24
1.2
1.4
30.97
31.42
nmol/l
—
6
61
17
143
1.19
0.23
1.1
1.0
0.41
1.83
u/ml
—
5
35
10
125
0.80
0.23
1.4
1.9
0.00
0.05
estimate
—
10
125
27
306
0.88
0.22
1.5
2.5
—
—
—
0
0
11
88
1.25
0.22
1.2
1.1
—
—
—
0
0
94
884
1.06
0.22
1.1
1.2
—
—
—
0
0
110
1040
1.06
0.22
1.3
1.4
—
—
—
0
0
57
526
1.08
0.21
1.3
1.3
—
—
—
0
0
13
107
1.22
0.21
1.3
1.6
8.77
9.34
ug/l
0.31
13
107
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
6.4
—
385.82
—
0
11
0
10
0.00
0.21
0.0
1.2
—
134.80
—
0
10
0
12
0.00
0.21
0.0
1.1
—
10.50
—
0
5
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
18
154
1.17
0.21
1.1
1.0
0.42
0.95
u/ml
—
7
51
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
28
249
1.13
0.20
1.3
1.4
1.21
1.11
promille
0.13
20
195
10
123
0.81
0.20
1.7
1.6
2.87
2.53
%
—
10
102
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
16
136
1.18
0.20
1.6
1.8
27.56
30.03
%
0.20
16
136
6
49
1.22
0.20
1.2
1.4
73.27
75.77
%
—
6
43
6
49
1.22
0.20
1.0
1.2
59.50
65.39
ug/l
—
6
49
9
114
0.79
0.20
1.9
1.5
11.74
23.29
%
—
9
104
18
155
1.16
0.19
1.0
1.1
—
—
—
0
0
492
4816
1.02
0.19
1.7
1.7
—
—
—
0
0
32
291
1.10
0.17
2.3
2.8
17.51
29.43
mg/l
2.30
25
208
68
722
0.94
0.17
1.2
1.2
—
—
—
0
0
12
101
1.19
0.16
1.4
1.9
—
—
—
0
0
8
70
1.14
0.16
3.8
6.5
8.54
8.28
mmol/l
—
8
70
8
71
1.13
0.16
1.8
1.9
—
—
—
0
0
84
883
0.95
0.16
1.2
1.1
0.54
0.63
ratio
—
7
139
328
3205
1.03
0.16
4.2
4.0
1.23
1.23
mmol/l
0.43
277
2756
34
312
1.09
0.15
1.1
1.2
323.16
363.65
nmol/l
0.48
25
262
54
506
1.07
0.15
1.2
1.1
—
—
—
0
0
30
328
0.91
0.15
1.1
1.2
125.67
107.35
pmol/l
1.97
30
328
54
507
1.07
0.15
1.2
1.1
—
—
—
0
0
57
537
1.06
0.14
1.2
1.1
1.11
1327.08
iu/ml
—
9
99
47
440
1.07
0.14
1.5
1.4
271.97
274.61
mosm/kgh2o
0.34
37
332
18
202
0.89
0.14
1.6
1.8
—
—
—
0
0
68
645
1.06
0.14
1.3
2.0
—
—
—
0
0
29
316
0.92
0.14
3.1
2.9
34.20
32.14
mg/l
0.03
21
224
349
3561
0.98
0.14
4.5
7.2
1.34
1.34
mmol/l
0.01
338
3496
40
429
0.93
0.14
1.3
1.5
—
—
—
0
0
17
151
1.13
0.13
1.0
1.1
1645.94
1560.98
miu/ml
0.10
17
151
150
1454
1.03
0.13
1.6
1.8
—
—
—
0
0
99
1029
0.96
0.13
1.3
1.4
—
—
—
0
0
21
190
1.11
0.12
3.4
2.6
729.67
1071.35
u/ml
0.89
21
190
554
5467
1.02
0.12
5.1
6.9
104.11
104.17
mmol/l
0.10
554
5462
244
2492
0.98
0.11
5.1
7.9
24.85
24.93
mmol/l
0.11
239
2478
1225
12344
0.99
0.11
3.5
3.3
—
—
—
0
0
42
445
0.94
0.11
1.7
1.7
—
—
—
0
0
955
9634
0.99
0.11
1.4
1.4
—
—
—
0
0
5
45
1.11
0.09
1.2
1.1
—
—
—
0
0
13
145
0.90
0.09
1.5
1.6
72.08
67.29
%
0.25
13
117
39
370
1.05
0.09
1.3
1.4
43179.47
92910.46
e6/l
0.68
19
255
355
3504
1.01
0.08
1.5
1.5
—
—
—
0
0
38
399
0.95
0.08
1.2
1.2
—
—
—
0
0
7
67
1.04
0.08
3.6
7.7
4.93
5.36
kpa
—
7
67
6
71
0.84
0.07
1.0
1.0
14.88
34.68
iu/ml
—
6
71
105
1024
1.03
0.07
2.3
2.4
3.66
3.62
g/l
0.10
100
971
30
284
1.06
0.07
1.3
1.3
—
—
—
0
0
7
80
0.87
0.07
1.7
1.5
—
—
—
0
0
7
84
0.83
0.07
1.1
1.2
—
—
—
0
0
93
954
0.97
0.07
1.3
1.2
1.54
1.57
g/l
0.49
93
954
9
85
1.06
0.07
1.1
1.1
—
—
—
0
0
33
346
0.95
0.06
1.3
1.5
27.18
30.08
%
0.17
17
209
90
878
1.03
0.06
2.6
3.4
979.51
859.26
u/ml
0.05
81
805
9
104
0.87
0.06
2.4
1.3
—
—
—
0
0
12
109
1.10
0.06
1.4
1.1
—
—
—
0
0
19
178
1.07
0.05
3.1
3.1
—
—
—
0
0
10
90
1.11
0.05
1.1
1.4
21.80
22.57
%
—
10
75
12
110
1.09
0.05
1.2
1.3
30.83
28.62
s
0.38
12
110
44
426
1.03
0.05
1.5
1.6
—
—
—
0
0
32
332
0.96
0.04
1.2
1.1
—
—
—
0
0
435
4325
1.01
0.03
1.5
1.6
—
—
—
0
0
34
351
0.97
0.03
1.0
1.1
—
—
—
0
0
48
491
0.98
0.03
1.5
2.8
—
—
—
0
0
71
698
1.02
0.03
1.3
1.9
—
—
—
0
0
14
132
1.06
0.02
1.8
1.5
66.86
334.95
nmol/24h
0.67
14
132
153
1518
1.01
0.02
2.9
3.4
93.12
3029.68
u/ml
0.96
134
1291
12
113
1.06
0.01
1.1
1.0
—
—
—
0
0
14
133
1.05
0.01
1.8
2.6
0.64
0.61
mmol/l
0.87
14
133
49
483
1.01
0.01
1.1
1.2
—
—
—
0
0
63
623
1.01
0.01
1.3
1.2
—
—
—
0
0
71
703
1.01
0.01
1.3
2.0
—
—
—
0
0
70
707
0.99
0.01
1.3
2.0
—
—
—
0
0
16
158
1.01
0.00
1.1
1.1
—
4.56
iu/ml
—
0
9
44
442
1.00
0.00
3.4
3.0
11.88
10.69
mmol/l
0.61
44
434
21
205
1.02
0.00
2.0
2.1
517.71
499.07
min
0.32
14
151
28
275
1.02
0.00
2.0
2.2
723.61
637.11
ml
0.33
18
178
79
792
1.00
0.00
2.3
2.6
34.03
34.98
umol/l
0.15
73
711
52
521
1.00
0.00
2.4
2.8
—
—
—
0
0
71
709
1.00
0.00
1.5
1.8
1.06
0.85
nmol/l
0.58
58
591
13
126
1.03
0.00
1.5
1.6
—
—
—
0
0
48
483
0.99
0.00
1.7
1.4
—
—
—
0
0
48
483
0.99
0.00
1.7
1.4
—
—
—
0
0
48
483
0.99
0.00
1.7
1.4
—
—
—
0
0
48
483
0.99
0.00
1.7
1.4
—
—
—
0
0
70
703
1.00
0.00
1.3
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
25.80
—
0
5
0
5
0.00
0.00
0.0
1.6
—
46.66
—
0
5
0
5
0.00
0.00
0.0
1.0
—
2341.80
—
0
5
0
5
0.00
0.00
0.0
2.2
—
1.71
—
0
5
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
8
87
0.92
0.00
4.9
4.7
—
—
—
0
0
8
83
0.96
0.00
1.1
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.2
45.28
48.04
mg/l
—
5
44
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
8
84
0.95
-0.00
1.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
329.67
—
0
9
0
9
0.00
-0.00
0.0
4.2
—
—
—
0
0
8
82
0.98
-0.00
3.3
2.4
13.50
422.57
ug/l
—
8
82
52
520
1.00
-0.00
1.2
1.2
2.55
4.80
u/ml
1.43
29
222
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
82
0.98
-0.00
1.0
1.1
—
—
—
0
0
5
51
0.98
-0.00
1.4
2.2
8.42
17.80
umol/l
—
5
51
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.02
—
0
6
11
110
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
1.30
—
0
6

Mortality – FinRegistry

Association

Association between endpoint H8_MENIERE and mortality.

Females

Parameter HR [95% CI] p-value
H8_MENIERE 0.876 [0.8, 0.96] 0.006
Birth year 0.991 [0.98, 1.0] 0.033

During the follow-up period (1.1.1998 — 31.12.2019), 1902 out of 13148 females with H8_MENIERE died.

Males

Parameter HR [95% CI] p-value
H8_MENIERE 0.777 [0.71, 0.85] < 0.001
Birth year 0.988 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 1269 out of 7015 males with H8_MENIERE died.

Mortality risk

Mortality risk for people of age

years, who have H8_MENIERE.

N-year risk Females Males
1 0.092% 0.158%
5 0.431% 0.937%
10 1.069% 2.318%
15 2.118% 4.412%
20 3.919% 7.457%

Relationships between endpoints

Index endpoint: H8_MENIERE – Ménière disease

GWS hits: 5

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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