vulvar carcinoma: A carcinoma that arises from epithelial cells of the mammalian vulva
Haemangioma and lymphangioma, any site
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_HEAMANGIOMA_LYMPHANGIOMA
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519870 |
1. Apply sex-specific ruleNone |
519870 |
2. Check conditionsNone |
519870 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
3572 |
4. Check minimum number of eventsNone |
3572 |
5. Include endpoints |
4001 |
6. Filter based on genotype QC (FinnGen only) |
3856 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D10-D36
- Name in latin
- Haemangioma sive lymphangioma, quovis loco
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 31154 | 18400 | 12629 |
| Only index persons | 26146 | 15515 | 10631 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.45 | 0.53 | 0.35 |
| Only index persons | 0.50 | 0.57 | 0.41 |
| Median age at first event (years) | |||
| Whole population | 37.79 | 37.79 | 37.66 |
| Only index persons | 42.29 | 42.73 | 41.64 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3856 | 2482 | 1374 |
| Unadjusted period prevalence (%) | 0.79 | 0.88 | 0.63 |
| Median age at first event (years) | 52.45 | 50.10 | 56.70 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 4001
- Matched controls
- 40009
TimeCodeWAS
↥TODO / Current known limitations:
- Only showing the top 500 codes, because showing all (sometimes 20k) makes the page too slow.
- Legend / how to read the glyphs.
- Proper column names.
- Show details (e.g. Fisher or Chi-square test, N cases and N controls) when clicking on a row.
- Explanation on the underlying data / how the TimeCodeWAS is done (e.g. matched cases / controls, eligibility).
- Download CSV not working.
- No filters and sorters.
- Limited amount of endpoints with TimeCodeWAS data.
- Cross-links to Risteys lab test pages for lab test codes.
2280A (2000402145)
D18.1 (45590982)
EAA10 (2001301885)
SMOKING-2-0-0 (2002330112)
SMOKING-1-1-0 (2002330116)
D18 (45755336)
Q27.88 (2000503318)
QAA40 (2001309765)
QXA25 (2001310041)
ZXC12 (2001311362)
SMOKING-2-2-4 (2002330109)
SMOKING-2-2-0 (2002330110)
SMOKING-2-3-0 (2002330113)
50373000 (4177340)
60621009 (4245997)
Q27.9 (45534372)
Q27.3 (45539270)
R22.0 (45548955)
D18.0 (45586089)
9736 (2000101671)
22700 (2000301258)
2281A (2000402146)
K76.80 (2000502934)
Q82.50 (2000503504)
AA1CG (2001300116)
AAB00 (2001300256)
TEA00 (2001301899)
EJA10 (2001302171)
UJF32 (2001305029)
JN1AE (2001305517)
JN1BG (2001305523)
JN1CG (2001305527)
JN1DG (2001305530)
JN3AD (2001305554)
JN3BD (2001305556)
JN3CD (2001305561)
NDR20 (2001307741)
QAA25 (2001309763)
QBE10 (2001309853)
QCE10 (2001309914)
QX3LT (2001310137)
TQW99 (2001310150)
TQX10 (2001310152)
SAA04 (2001310277)
SBB00 (2001310298)
WZC05 (2001310886)
WZC10 (2001310887)
WZC20 (2001310890)
XX6KT (2001311143)
ZXA05 (2001311347)
ZXC10 (2001311360)
ZXC50 (2001311370)
S04 (2002000969)
SMOKING-2-3-5 (2002330114)
SMOKING-1-1-1 (2002330115)
A10AB01 (21600715)
A10AD01 (21600729)
19875-4 (3001668)
14920-3 (3008486)
3016-3 (3009201)
19176-7 (3015916)
1798-8 (3016771)
20155-8 (3023550)
1223G0001X (38003675)
19 (38004464)
69970-2 (42868459)
69982-7 (42868471)
69983-5 (42868472)
D22.5 (45542688)
R93.2 (45544168)
L82 (45548208)
K80.2 (45552951)
Q27.4 (45558400)
D13.4 (45561892)
R10.1 (45568111)
D22.9 (45571603)
R23.8 (45573020)
E10.9 (45581351)
D37.6 (45586102)
L57.0 (45591640)
D22 (45595739)
D64.9 (45600610)
K76.0 (45601189)
OMOP4822020 (45756819)
C5 (903277)
24 (38004467)
207NI0002X (38003841)
4 (38004449)
106 (44777669)
10 (38004455)
2 (38004447)
22 (8756)
OP (9202)
IP (9201)
OMOP5117446 (33004)
21 (8717)
13 (38004458)
ZY020 (2001311600)
ER (9203)
GD1AA (2001303617)
D48.1 (45566694)
83084-4 (42529201)
24108-3 (3022914)
20 (38004465)
14 (38004459)
SPAT1153 (2001700254)
JN3AE (2001305555)
Z2221 (2001311556)
11 (38004456)
QAE10 (2001309784)
29 (38004472)
18 (38004463)
OMOP4822458 (581477)
Z3226 (2001311560)
R22.1 (45592412)
117617002 (4035726)
ZXD10 (2001311387)
Z01.8 (45581003)
14338-8 (3013742)
QDE10 (2001309980)
R10.4 (45568113)
93 (38004510)
UJD10 (2001304788)
29760-6 (3005772)
R22.9 (45577788)
16 (38004461)
WX408 (2001310808)
G47.3 (45562094)
14631-6 (3006140)
34714-6 (3032080)
24419-4 (3002256)
ZXE00 (2001311394)
ZXE10 (2001311401)
1 (38004446)
E78.01 (2000501514)
66121-5 (40768804)
14749-6 (3013826)
WX110 (2001310767)
S18 (2002000983)
WX002 (2001310758)
2039-6 (3003785)
EP1AE (2001302284)
19926-5 (3011505)
19870-5 (3020158)
20150-9 (3024653)
WX402 (2001310806)
D48.5 (45586113)
K57.3 (45567316)
261QX0200X (38004268)
251B00000X (38004193)
60517-0 (40763571)
6 (38004451)
I10 (45591453)
19072-8 (3016431)
5894-1 (3033658)
1988-5 (3020460)
37 (38004477)
WX404 (2001310807)
14798-3 (3022948)
40 (38004480)
2458-8 (3007164)
3034-6 (3004789)
J01DB01 (21602870)
6768-6 (3035995)
QX2XE (2001310033)
D01 (2002000300)
51480-2 (3031040)
R10.3 (45534426)
5802-4 (3021601)
ZXA00 (2001311346)
25 (38004468)
31017-7 (3019050)
1920-8 (3013721)
58410-2 (40761511)
34531-4 (3044640)
R07.4 (45558450)
24357-6 (3037467)
OMOP4822461 (32036)
890-4 (3001079)
14682-9 (3020564)
2951-2 (3019550)
R22.3 (45548956)
2823-3 (3023103)
R02AX02 (1588667)
M01AE01 (21603967)
62238-1 (40764999)
E11.9 (45561952)
1751-7 (3024561)
N02AX02 (21604298)
57782-5 (40760892)
66 (38004491)
6598-7 (3019800)
R4110 (2001310233)
WZB00 (2001310884)
20570-8 (3009542)
26515-7 (3007461)
28539-5 (3035941)
30428-7 (3024731)
26453-1 (3026361)
718-7 (3000963)
26464-8 (3010813)
715-3 (3021589)
30385-9 (3002385)
4537-7 (3013707)
50554-5 (3029287)
2324-2 (3026910)
Z71.2 (45552100)
77 (38004496)
ZXE20 (2001311408)
28540-3 (3003338)
P01AB01 (21604857)
OMOP4822462 (581458)
1742-6 (3006923)
51483-6 (3030467)
N02BE01 (21604344)
A02BC02 (21600097)
A02BC05 (21600100)
2695-5 (3026782)
UJF30 (2001305028)
30391-7 (3002582)
N02BF01 (955005)
WZC00 (2001310885)
26449-9 (3013115)
26444-0 (3006315)
26484-6 (3001604)
26474-7 (3019198)
30405-5 (3018095)
OMOP4822009 (45756830)
EB1HA (2001301913)
K35.9 (45557651)
751-8 (3013650)
30180-4 (3022096)
26450-7 (3006504)
26485-3 (3019069)
26478-8 (3002030)
26511-6 (3018010)
30383-4 (3000850)
H02AB06 (21602734)
A07EA01 (21600653)
A12AA20 (21600872)
G03CA03 (21602517)
N02AJ06 (1123647)
J01AA02 (21602800)
R03AC02 (21603256)
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_HEAMANGIOMA_LYMPHANGIOMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_HEAMANGIOMA_LYMPHANGIOMA | 0.963 [0.86, 1.08] | 0.536 |
| Birth year | 0.995 [0.99, 1.0] | 0.208 |
During the follow-up period (1.1.1998 — 31.12.2019), 979 out of 13789 females with CD2_BENIGN_HEAMANGIOMA_LYMPHANGIOMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_HEAMANGIOMA_LYMPHANGIOMA | 1.126 [1.0, 1.27] | 0.046 |
| Birth year | 0.987 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 1156 out of 9406 males with CD2_BENIGN_HEAMANGIOMA_LYMPHANGIOMA died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_HEAMANGIOMA_LYMPHANGIOMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.066% | 0.222% |
| 5 | 0.478% | 1.371% |
| 10 | 1.339% | 3.372% |
| 15 | 2.605% | 6.383% |
| 20 | 4.503% | 10.786% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_HEAMANGIOMA_LYMPHANGIOMA – Haemangioma and lymphangioma, any site
GWS hits: 1