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Brain astrocytoma, helper endpoint

HLP_C3_ASTROCYTOMA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C71
  • Cancer registry: Morphology ICD-O-3 9400
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

178

4. Check minimum number of events

None

178

5. Include endpoints

None

178

6. Filter based on genotype QC (FinnGen only)

161

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 161 80 81
Unadjusted period prevalence (%) 0.03 0.03 0.04
Median age at first event (years) 39.95 38.20 41.68

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
166
Matched controls
1660
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
575.3
276.3
129
10
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
136.4
218.5
128
40
130
Kela drug reimbursment
Malignant tumour
129.5
215.0
135
54
N03AX14
ATC
levetiracetam; systemic
137.6
192.0
102
19
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
146.2
177.9
92
14
L01AX03
ATC
temozolomide; systemic
753.7
149.6
127
7
H02AB02
ATC
dexamethasone; systemic
49.7
149.5
124
93
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
48.6
147.8
124
95
A04AA02
ATC
granisetron; systemic, transdermal
51.5
141.1
95
42
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
106.2
123.0
65
10
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
42.5
105.5
70
28
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
73.8
103.5
58
12
WF002
NOMESCO Finland
Radical radiotherapy
37.4
99.5
69
31
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
792.4
90.4
81
*
N03AF02
ATC
oxcarbazepine; oral
29.6
82.0
61
32
9400/3-C71.1
ICD-O-3
Astrocytoma, NOS, of frontal lobe
+∞
68.6
61
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
23.0
67.2
55
35
R56.8
ICD-10 Finland
Other and unspecified convulsions
19.8
65.8
59
45
A03FA01
ATC
metoclopramide; systemic, rectal
13.6
65.3
112
220
WF003
NOMESCO Finland
Adjuvant radiotherapy
32.9
64.2
44
18
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
163.0
61.9
62
6
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
190.7
61.8
61
5
9400/3-C71.9
ICD-O-3
Astrocytoma, NOS, of brain, NOS
+∞
58.9
53
*
XA800
NOMESCO Finland
Neuropsychological investigation
17.3
56.9
54
45
C71.21
ICD-10 Finland
Malignant tumor of temporal lobe grade II glioma
+∞
56.5
51
*
A04AA01
ATC
ondansetron; systemic, rectal
14.8
54.6
58
58
ZXC95
NOMESCO Finland
Use of surgical navigator
107.2
54.2
57
8
G40.9
ICD-10 Finland
Epilepsy, unspecified
27.1
52.1
38
18
AA1AD
NOMESCO Finland
CT of head and brain
10.4
51.7
111
269
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
278.7
43.1
42
*
Z51.5
ICD-10 Finland
Palliative care
13.7
42.4
45
44
XX3DW
NOMESCO Finland
Time consuming IT work
9.6
40.6
60
92
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
9.2
40.6
64
106
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
+∞
39.1
36
*
N03AX18
ATC
lacosamide; systemic
78.6
33.7
37
6
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
7.4
33.3
64
129
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
106.2
32.1
34
*
9400/3-C71.2
ICD-O-3
Astrocytoma, NOS, of temporal lobe
+∞
31.2
29
*
C71.1
ICD-10 Finland
Malignant neoplasm: Frontal lobe
+∞
26.8
25
*
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
306.0
26.5
26
*
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
106.8
25.5
27
*
C71.2
ICD-10 Finland
Malignant neoplasm: Temporal lobe
292.2
25.4
25
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
49.6
24.5
29
7
ZXC40
NOMESCO Finland
Use of ultrasound
64.0
23.9
27
5
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
265.1
23.2
23
*
WX882
NOMESCO Finland
High dependency care
34.7
22.8
29
10
WX872
NOMESCO Finland
Intensive care
10.4
21.8
26
29
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
+∞
20.2
19
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
36.4
19.9
25
8
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
17.0
19.5
31
22
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
79.5
19.2
21
*
C71.22
ICD-10 Finland
Malignant tumor of temporal lobe grade III glioma
+∞
19.1
18
*
N03AB02
ATC
phenytoin; systemic
37.8
18.5
23
7
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
200.5
17.9
18
*
WZC00
NOMESCO Finland
Treatment plan or consultation
4.0
17.6
98
437
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
35.9
17.5
22
7
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
56.4
17.4
20
*
C71.31
ICD-10 Finland
Malignant tumor of the parietal lobe grand II glioma
+∞
17.0
16
*
N03AG01
ATC
valproic acid; systemic, rectal
6.1
16.0
31
60
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
94.2
15.9
17
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
175.9
15.8
16
*
N03AF01
ATC
carbamazepine; oral, rectal
7.9
15.7
23
33
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
62.7
15.1
17
*
A02BC02
ATC
pantoprazole; systemic
4.5
14.7
134
798
N05BA09
ATC
clobazam; oral
30.4
14.6
19
7
C71.23
ICD-10 Finland
Malignant tumor of temporal lobe grade IV glioma
+∞
13.7
13
*
C71.29
ICD-10 Finland
Malignant tumor in temporal lobe other or unspecified histology
151.9
13.7
14
*
R4150
NOMESCO Finland
Neuropsychological rehabilitation
18.7
13.4
20
12
ZX050
NOMESCO Finland
Stereotactic radiotherapy
54.5
13.1
15
*
N05CD08
ATC
midazolam; nasal, systemic
17.3
13.0
20
13
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
6.7
13.0
22
37
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
35.1
12.8
16
5
G40.10
ICD-10 Finland
Simple partial seizures
75.8
12.8
14
*
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
75.8
12.8
14
*
WZC30
NOMESCO Finland
Teaching
3.8
12.1
46
153
WX402
NOMESCO Finland
General anaesthesia
3.4
12.1
61
244
C71.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of brain
70.0
11.8
13
*
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
70.0
11.8
13
*
ZXE20
NOMESCO Finland
More than three and less than five hours
4.3
11.7
34
93
C71.81
ICD-10 Finland
Overall malignant tumor of the brain grade II glioma
+∞
11.6
11
*
C71.13
ICD-10 Finland
Malignant tumor of frontal lobe grade IV glioma
+∞
11.6
11
*
N03AX23
ATC
brivaracetam; systemic
128.6
11.6
12
*
C71.30
ICD-10 Finland
Malignant tumor in parietal lobe without histology
128.6
11.6
12
*
ZXM40
NOMESCO Finland
Use of fluorescent substance
128.6
11.6
12
*
C71.19
ICD-10 Finland
Malignant tumor of frontal lobe other or unspecified histology
128.6
11.6
12
*
C71.01
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade II glioma
128.6
11.6
12
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.2
10.8
58
239
H53.4
ICD-10 Finland
Visual field defects
13.3
10.6
18
15
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
10.5
10
*
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
35.0
10.5
13
*
183
Kela drug reimbursment
Lamotrigin and topiramate
16.3
9.7
15
10
9400/3-C71.0
ICD-O-3
Astrocytoma, NOS, of cerebrum
+∞
9.5
9
*
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
39.0
9.1
11
*
C71.99
ICD-10 Finland
Malignant tumor in unspecified localization in the brain other or unspecified histology
39.0
9.1
11
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
94.7
8.5
9
*
H02AB09
ATC
hydrocortisone; systemic
10.3
8.5
16
17
H02AB04
ATC
methylprednisolone; systemic
3.7
8.4
30
94
N76
ICPC
Neoplasm nervous system unspecified
+∞
8.4
8
*
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
15.5
8.4
13
9
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
35.2
8.2
10
*
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
14.0
8.0
13
10
N02AA05
ATC
oxycodone; systemic
3.2
8.0
37
137
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
26.4
7.7
10
*
C71.00
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles without histology
83.7
7.5
8
*
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
83.7
7.5
8
*
9400/3-C71.3
ICD-O-3
Astrocytoma, NOS, of parietal lobe
+∞
7.3
7
*
C71.80
ICD-10 Finland
Overall malignant tumor of the brain without histology
+∞
7.3
7
*
R47.0
ICD-10 Finland
Dysphasia and aphasia
21.1
7.2
10
5
A28
ICPC
Limited function/disability NOS
3.3
6.9
28
95
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
10.0
6.9
13
14
AA1BD
NOMESCO Finland
Extensive CT of head and brain
8.4
6.8
14
18
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
13.0
6.7
11
9
N03AX09
ATC
lamotrigine; oral
3.9
6.5
20
56
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
72.5
6.5
7
*
G40.89
ICD-10 Finland
Other epilepsy
72.5
6.5
7
*
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
27.8
6.3
8
*
2151
FHL
Resection, big brain
+∞
6.3
6
*
C71.91
ICD-10 Finland
Malignant tumor in unspecified location in the brain grade II glioma
+∞
6.3
6
*
AA5NK
NOMESCO Finland
Tractography within white matter of central nervous system
+∞
6.3
6
*
C71.40
ICD-10 Finland
Malignant tumor of the occipital lobe without histology
+∞
6.3
6
*
C71.32
ICD-10 Finland
Malignant tumor of parietal lobe grade III glioma
+∞
6.3
6
*
C71.82
ICD-10 Finland
Overall malignant tumor of the brain grade III glioma
+∞
6.3
6
*
G40
ICD-10 Finland
Epilepsy
13.2
6.2
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
97
102
21.47
92.51
1.4
1.3
—
—
—
0
0
87
128
13.18
63.42
5.9
13.4
0.60
1.62
mmol/l
2.16
69
104
87
129
13.07
63.01
6.0
13.3
7.41
7.42
ph
0.29
59
74
64
80
12.39
51.62
4.8
6.8
23.91
25.36
mmol/l
2.62
64
80
131
608
6.48
25.07
7.4
8.0
1.20
1.21
mmol/l
1.07
119
527
106
469
4.49
19.97
2.3
2.3
—
—
—
0
0
111
541
4.17
17.49
3.4
1.9
—
—
—
0
0
123
666
4.27
16.14
2.9
2.9
—
—
estimate
—
0
0
26
42
7.15
16.00
2.0
1.5
—
—
—
0
0
25
20
14.49
14.97
2.1
1.4
—
—
—
0
0
39
110
4.33
12.93
6.9
8.9
—
—
—
0
0
93
470
3.23
12.49
10.7
6.8
—
—
—
0
0
22
21
11.89
12.19
2.0
1.2
—
—
—
0
0
97
513
3.14
11.85
4.0
11.1
1.01
1.17
inr
10.07
79
426
132
844
3.75
11.53
18.0
10.6
3.43
3.98
e9/l
2.79
114
742
23
48
5.40
10.85
2.0
1.4
975.06
27.31
e6/l
0.49
16
35
23
48
5.40
10.85
1.9
1.3
68.06
17.64
e6/l
0.63
16
33
82
418
2.90
10.33
9.3
3.6
2.38
2.35
mmol/l
1.62
77
381
25
60
4.73
10.04
5.4
13.9
—
—
—
0
0
117
746
2.93
9.26
10.8
6.9
0.53
0.55
e9/l
0.71
99
658
117
748
2.91
9.17
10.7
6.9
0.03
0.04
e9/l
4.87
98
659
119
776
2.88
8.83
10.9
7.4
0.12
0.19
e9/l
8.19
102
693
116
770
2.68
7.90
10.9
7.0
1.50
1.84
e9/l
5.38
98
692
83
472
2.52
7.85
1.3
1.6
—
—
—
0
0
109
704
2.60
7.83
11.0
6.9
60.16
57.01
%
1.75
109
688
89
540
2.40
7.09
4.5
5.2
36.96
36.82
g/l
0.08
84
517
113
1402
0.39
6.81
3.4
4.4
4.91
4.70
mmol/l
1.32
103
1333
113
1398
0.40
6.56
3.4
4.4
1.40
1.41
mmol/l
0.13
102
1324
117
1414
0.42
5.79
3.5
4.8
3.04
2.83
mmol/l
1.73
105
1340
66
379
2.23
5.69
2.8
3.7
7.40
7.40
ph
0.31
40
273
9
8
11.80
5.35
1.8
3.0
36.56
39.38
%
—
9
8
9
8
11.80
5.35
3.6
6.0
9.33
9.88
%
—
9
8
59
331
2.21
5.33
3.5
4.5
—
—
—
0
0
93
632
2.07
5.01
15.7
11.0
0.00
0.00
e9/l
0.37
70
520
12
23
5.54
4.55
1.8
1.5
—
—
—
0
0
110
1327
0.49
4.20
3.1
3.7
1.35
1.28
mmol/l
0.43
99
1245
106
1278
0.53
3.62
3.9
5.1
36.15
38.01
mmol/mol
2.65
95
1224
111
1309
0.54
3.24
4.2
4.2
5.49
5.77
mmol/l
3.02
104
1226
69
480
1.75
3.02
2.7
3.1
13.33
29.45
ng/l
1.64
46
277
45
666
0.56
2.85
2.1
2.7
—
—
—
0
0
59
408
1.69
2.56
9.5
6.6
—
—
—
0
0
0
61
0.00
2.29
0.0
1.2
—
—
—
0
0
52
367
1.61
2.03
4.7
3.1
—
—
—
0
0
19
333
0.52
2.00
3.3
3.6
26.22
64.09
mg/l
1.44
13
221
8
185
0.40
1.95
1.0
1.3
—
—
—
0
0
20
342
0.53
1.95
3.6
4.3
4.82
9.35
mg/mmol
0.60
12
220
7
22
3.27
1.90
3.1
2.4
8.81
8.86
kpa
—
7
22
7
22
3.27
1.90
3.1
2.4
5.19
4.95
kpa
—
7
22
7
22
3.27
1.90
3.1
2.4
2.27
2.53
mmol/l
—
7
15
5
12
4.26
1.83
1.4
1.3
93.04
91.07
%
—
5
12
151
1586
0.47
1.81
40.7
20.6
135.83
138.73
g/l
1.79
151
1575
48
342
1.57
1.78
2.4
2.6
—
—
—
0
0
151
1585
0.48
1.76
39.5
20.5
30.50
30.25
pg
1.11
151
1574
151
1585
0.48
1.76
39.5
20.6
6.50
6.59
e9/l
0.20
151
1557
151
1585
0.48
1.76
40.4
20.9
40.44
41.37
%
2.24
151
1572
151
1585
0.48
1.76
39.6
20.5
4.51
4.61
e12/l
1.81
151
1557
0
46
0.00
1.73
0.0
3.0
—
874.76
—
0
38
151
1584
0.48
1.70
39.7
20.5
90.69
90.32
fl
0.52
151
1573
151
1583
0.49
1.65
39.5
20.6
246.44
252.15
e9/l
0.31
151
1561
19
107
1.88
1.63
1.2
1.2
—
27.06
—
0
7
6
20
3.07
1.59
1.3
2.5
19.20
17.02
%
—
6
20
6
22
2.79
1.45
2.8
3.1
—
—
—
0
0
151
1406
1.82
1.40
25.4
14.3
3.90
3.94
mmol/l
1.55
151
1375
151
1407
1.81
1.38
26.1
14.2
139.23
139.72
mmol/l
1.30
151
1381
31
213
1.56
1.33
2.8
2.6
4.28
2.62
e6/l
0.25
16
92
35
248
1.52
1.31
2.1
2.9
28.27
703.13
ng/l
0.82
15
153
20
124
1.70
1.28
4.3
4.2
1.60
0.91
%
—
10
34
19
294
0.60
1.27
1.7
1.5
—
—
—
0
0
48
608
0.70
1.23
3.1
3.1
6.34
6.20
ph
0.36
32
347
29
403
0.66
1.21
3.1
3.5
0.00
0.00
estimate
—
10
151
14
230
0.57
1.18
1.2
1.3
—
—
—
0
0
120
1308
0.70
1.18
4.3
5.1
1.57
1.75
mu/l
1.52
113
1230
0
33
0.00
1.17
0.0
3.2
—
61.58
—
0
33
0
36
0.00
1.15
0.0
1.1
—
—
—
0
0
10
180
0.53
1.15
1.1
1.3
—
—
—
0
0
7
32
2.24
1.09
3.1
3.3
7.43
7.41
ph
—
7
32
26
361
0.67
1.08
1.1
1.4
1.73
2.34
g/l
2.50
12
232
9
160
0.54
1.04
1.1
1.5
—
—
—
0
0
15
232
0.61
1.01
2.2
2.8
0.61
0.77
ug/l
—
8
126
27
192
1.49
1.01
1.3
1.6
—
—
—
0
0
61
723
0.75
0.97
2.5
3.1
89.21
92.79
ug/l
0.09
55
692
21
296
0.67
0.94
1.3
1.9
—
—
—
0
0
63
740
0.76
0.92
3.3
3.5
0.00
0.00
estimate
-0.00
12
156
6
30
2.04
0.88
2.5
19.6
—
—
—
0
0
10
162
0.59
0.82
1.4
1.5
—
—
—
0
0
97
868
1.28
0.82
3.9
4.3
—
56.92
—
0
13
65
751
0.78
0.81
3.3
3.6
0.00
0.00
estimate
-0.00
12
146
5
96
0.51
0.81
1.0
1.1
—
—
—
0
0
46
374
1.32
0.80
2.5
2.7
0.14
0.18
e6/l
0.26
32
270
65
747
0.79
0.76
3.1
3.5
0.00
0.00
estimate
-0.00
12
156
17
117
1.50
0.75
4.0
4.3
0.14
0.23
%
—
7
26
9
58
1.58
0.71
1.1
1.3
—
—
—
0
0
7
117
0.58
0.71
1.1
1.1
—
—
—
0
0
7
41
1.74
0.71
1.6
1.1
—
—
—
0
0
7
41
1.74
0.71
1.6
1.1
—
—
—
0
0
36
442
0.76
0.70
3.2
2.8
0.00
0.01
estimate
—
10
129
10
61
1.68
0.70
2.4
1.8
20.40
20.74
s
—
10
53
12
178
0.65
0.69
1.3
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
12
172
0.67
0.60
2.2
2.0
—
—
—
0
0
0
22
0.00
0.60
0.0
1.4
—
—
—
0
0
5
88
0.55
0.58
1.8
2.2
—
—
—
0
0
8
122
0.64
0.57
2.0
1.7
—
—
—
0
0
43
363
1.25
0.56
7.0
4.7
—
—
—
0
0
12
82
1.50
0.56
1.8
1.9
—
—
—
0
0
149
1436
1.37
0.54
23.7
13.4
19.59
21.91
mg/l
0.55
141
1148
50
572
0.82
0.52
3.3
3.2
0.00
0.00
estimate
-0.00
11
137
7
46
1.54
0.49
2.1
1.6
0.16
0.39
nmol/l
—
7
41
8
116
0.67
0.47
2.0
1.7
—
—
—
0
0
5
84
0.58
0.47
1.0
1.2
—
—
—
0
0
14
185
0.73
0.46
1.1
2.3
—
—
—
0
0
18
139
1.33
0.46
1.1
1.2
—
—
—
0
0
43
372
1.21
0.45
2.2
2.6
—
—
estimate
—
0
0
43
492
0.83
0.45
1.8
2.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
17
0.00
0.41
0.0
2.2
—
—
—
0
0
0
18
0.00
0.40
0.0
3.7
—
—
—
0
0
101
1070
0.86
0.40
3.8
4.4
14.23
14.58
pmol/l
0.73
94
1003
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.9
—
11.58
—
0
19
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
15
116
1.32
0.38
4.1
4.2
1.10
0.83
%
—
5
29
9
69
1.32
0.38
1.3
3.5
7.44
7.41
ph
—
9
57
121
1262
0.85
0.37
32.6
16.5
13.34
13.34
%
0.01
121
1251
9
123
0.72
0.36
1.9
1.7
—
—
—
0
0
9
124
0.71
0.36
1.8
1.7
—
—
—
0
0
9
124
0.71
0.36
1.9
1.7
—
—
—
0
0
146
1496
0.80
0.34
20.6
11.5
—
—
—
0
0
6
46
1.32
0.33
1.5
3.8
—
—
—
0
0
15
120
1.27
0.31
4.1
4.6
0.00
0.07
%
—
5
27
44
395
1.16
0.31
1.5
1.8
—
—
—
0
0
9
117
0.76
0.28
3.0
3.2
—
—
—
0
0
29
328
0.86
0.26
2.8
3.4
1.02
1.02
kg/l
0.66
19
217
9
72
1.26
0.26
1.1
1.2
—
—
—
0
0
48
441
1.12
0.24
2.6
2.8
22.38
195.19
e6/l
0.61
34
336
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
147.58
—
0
13
0
13
0.00
0.21
0.0
1.2
—
75.08
—
0
13
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
2.8
—
1.03
—
0
8
0
14
0.00
0.20
0.0
3.4
—
—
—
0
0
0
14
0.00
0.20
0.0
5.2
—
2.86
—
0
14
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
19
166
1.16
0.19
1.8
1.6
1267.80
1184.94
nmol/l
—
10
127
5
70
0.71
0.17
1.0
2.5
—
—
—
0
0
11
92
1.21
0.16
2.3
4.1
62.86
75.63
e9/l
—
5
63
6
76
0.78
0.16
1.0
1.1
1.43
1.48
g/l
—
6
76
6
77
0.77
0.16
1.0
1.1
0.78
0.90
g/l
—
6
77
50
530
0.92
0.16
1.7
1.9
93.19
101.00
pmol/l
0.61
27
269
6
78
0.76
0.16
1.2
1.6
—
—
—
0
0
6
80
0.74
0.16
1.2
1.7
—
—
—
0
0
9
80
1.13
0.15
1.7
2.1
8.77
6.25
ug/l
—
9
71
7
85
0.82
0.15
3.9
3.6
67.29
79.31
ng/l
—
7
76
30
276
1.11
0.15
1.4
1.7
—
—
—
0
0
8
98
0.81
0.14
1.9
1.5
—
—
—
0
0
150
1516
0.89
0.11
20.7
10.9
29.21
28.34
u/l
0.21
150
1494
30
320
0.92
0.11
2.0
2.0
1.84
2.71
mg/l
3.15
24
279
31
330
0.93
0.10
1.5
1.8
1.19
1.22
mg/l
0.02
22
252
6
53
1.14
0.09
1.0
1.1
—
—
—
0
0
6
73
0.82
0.08
1.3
3.1
25.33
24.26
mmol/l
—
6
73
50
518
0.95
0.07
3.1
3.5
46.92
60.62
e6/l
0.13
34
357
36
346
1.05
0.06
1.4
1.5
17.37
20.43
nmol/l
0.75
31
303
11
120
0.91
0.05
1.6
3.6
6.05
5.72
kpa
0.62
11
115
17
179
0.94
0.03
2.1
2.9
10.42
7.39
umol/l
0.18
12
162
16
168
0.95
0.02
1.3
1.7
—
—
—
0
0
151
1516
0.96
0.00
30.4
15.9
69.56
75.41
umol/l
3.57
151
1500
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
28.57
—
0
7
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
185.67
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
11.82
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
57.00
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
0.00
—
0
5
0
6
0.00
-0.00
0.0
6.2
—
10.49
—
0
6
0
6
0.00
-0.00
0.0
9.7
—
39.35
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
1999.00
—
0
5
0
8
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
2.67
—
0
6
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
55
0.91
-0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: HLP_C3_ASTROCYTOMA – Brain astrocytoma, helper endpoint

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).