Brain astrocytoma

C3_ASTROCYTOMA

astrocytoma: A glial tumor of the brain or spinal cord showing astrocytic differentiation. It includes the following clinicopathological entities: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, pleomorphic xanthoastrocytoma, subependymal giant cell astrocytoma, and glioblastoma.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • HLP_C3_ASTROCYTOMA
178

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C71
  • Cause of death: ICD-9 191
  • Cause of death: ICD-8 191
  • Cancer registry: Topography ICD-O-3 C71
  • Cancer registry: Morphology ICD-O-3 9400
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

178

4. Check minimum number of events

None

178

5. Include endpoints

178

6. Filter based on genotype QC (FinnGen only)

161

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE
Control conditions
not HLP_C3_ASTROCYTOMA

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 161 80 81
Unadjusted period prevalence (%) 0.03 0.03 0.04
Median age at first event (years) 39.95 38.20 41.68

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
166
Matched controls
1660
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
161.1
228.0
128
34
N03AX14
ATC
levetiracetam; systemic
238.9
207.9
102
11
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
186.4
183.9
92
11
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
71.3
175.7
124
66
130
Kela drug reimbursment
Malignant tumour
+∞
174.1
135
*
L01AX03
ATC
temozolomide; systemic
+∞
160.6
127
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
3048.3
160.0
129
*
H02AB02
ATC
dexamethasone; systemic
598.7
143.6
124
8
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
106.2
123.0
65
10
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
66.5
120.1
70
18
A04AA02
ATC
granisetron; systemic, transdermal
2164.9
110.8
95
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
73.8
103.5
58
12
A03FA01
ATC
metoclopramide; systemic, rectal
24.2
101.1
112
131
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
+∞
93.9
81
*
A04AA01
ATC
ondansetron; systemic, rectal
49.0
93.7
58
18
XX3DW
NOMESCO Finland
Time consuming IT work
34.2
85.8
60
27
N03AF02
ATC
oxcarbazepine; oral
29.6
82.0
61
32
WF002
NOMESCO Finland
Radical radiotherapy
+∞
78.5
69
*
Z51.5
ICD-10 Finland
Palliative care
43.7
71.8
45
14
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
+∞
69.8
62
*
9400/3-C71.1
ICD-O-3
Astrocytoma, NOS, of frontal lobe
+∞
68.6
61
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
19.8
65.8
59
45
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
477.3
65.4
61
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
61.3
55
*
XA800
NOMESCO Finland
Neuropsychological investigation
19.5
60.9
54
40
9400/3-C71.9
ICD-O-3
Astrocytoma, NOS, of brain, NOS
+∞
58.9
53
*
AA1AD
NOMESCO Finland
CT of head and brain
11.7
57.3
111
245
ZXC95
NOMESCO Finland
Use of surgical navigator
171.7
57.1
57
5
C71.21
ICD-10 Finland
Malignant tumor of temporal lobe grade II glioma
+∞
56.5
51
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
48.3
44
*
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
+∞
46.0
42
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
20.2
45.8
38
24
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
10.5
45.2
64
94
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
+∞
39.1
36
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
36.9
34
*
N03AX18
ATC
lacosamide; systemic
94.3
34.5
37
5
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
7.4
33.3
64
129
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
380.7
32.0
31
*
9400/3-C71.2
ICD-O-3
Astrocytoma, NOS, of temporal lobe
+∞
31.2
29
*
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
+∞
29.0
27
*
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
+∞
27.9
26
*
WZC00
NOMESCO Finland
Treatment plan or consultation
5.6
27.2
98
342
C71.2
ICD-10 Finland
Malignant neoplasm: Temporal lobe
+∞
26.8
25
*
C71.1
ICD-10 Finland
Malignant neoplasm: Frontal lobe
+∞
26.8
25
*
ZXC40
NOMESCO Finland
Use of ultrasound
160.0
26.5
27
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
58.1
25.2
29
6
WX882
NOMESCO Finland
High dependency care
43.5
23.9
29
8
WX872
NOMESCO Finland
Intensive care
10.4
21.8
26
29
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
88.1
21.3
23
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
126.0
21.1
22
*
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
238.7
21.1
21
*
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
+∞
20.2
19
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
225.8
20.0
20
*
WZC30
NOMESCO Finland
Teaching
5.5
19.3
46
109
C71.22
ICD-10 Finland
Malignant tumor of temporal lobe grade III glioma
+∞
19.1
18
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
+∞
19.1
18
*
N03AB02
ATC
phenytoin; systemic
44.1
19.1
23
6
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
29.1
18.9
25
10
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
+∞
18.0
17
*
N03AG01
ATC
valproic acid; systemic, rectal
6.7
17.5
31
55
N02AA05
ATC
oxycodone; systemic
5.7
17.1
37
80
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
31.4
17.0
22
8
C71.31
ICD-10 Finland
Malignant tumor of the parietal lobe grand II glioma
+∞
17.0
16
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
188.1
16.8
17
*
A02BC02
ATC
pantoprazole; systemic
5.0
16.7
134
760
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
15.9
15
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
175.9
15.8
16
*
ZXE20
NOMESCO Finland
More than three and less than five hours
5.6
15.8
34
73
N05CD08
ATC
midazolam; nasal, systemic
28.2
15.1
20
8
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
+∞
14.8
14
*
C71.29
ICD-10 Finland
Malignant tumor in temporal lobe other or unspecified histology
+∞
14.8
14
*
N05BA09
ATC
clobazam; oral
30.4
14.6
19
7
WX402
NOMESCO Finland
General anaesthesia
3.7
14.2
61
223
R4150
NOMESCO Finland
Neuropsychological rehabilitation
20.5
13.8
20
11
C71.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of brain
+∞
13.7
13
*
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
+∞
13.7
13
*
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
+∞
13.7
13
*
C71.23
ICD-10 Finland
Malignant tumor of temporal lobe grade IV glioma
+∞
13.7
13
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.7
13.7
58
209
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
44.0
13.4
16
*
G40.10
ICD-10 Finland
Simple partial seizures
75.8
12.8
14
*
C71.19
ICD-10 Finland
Malignant tumor of frontal lobe other or unspecified histology
+∞
12.7
12
*
C71.01
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade II glioma
+∞
12.7
12
*
ZXM40
NOMESCO Finland
Use of fluorescent substance
+∞
12.7
12
*
C71.30
ICD-10 Finland
Malignant tumor in parietal lobe without histology
+∞
12.7
12
*
H53.4
ICD-10 Finland
Visual field defects
20.0
12.4
18
10
C71.13
ICD-10 Finland
Malignant tumor of frontal lobe grade IV glioma
+∞
11.6
11
*
C71.81
ICD-10 Finland
Overall malignant tumor of the brain grade II glioma
+∞
11.6
11
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
11.6
11
*
C71.99
ICD-10 Finland
Malignant tumor in unspecified localization in the brain other or unspecified histology
+∞
11.6
11
*
N03AX23
ATC
brivaracetam; systemic
128.6
11.6
12
*
N03AF01
ATC
carbamazepine; oral, rectal
9.7
11.5
23
27
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
10.5
10
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
10.5
10
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
58.5
9.8
11
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.3
9.6
44
163
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
23.3
9.5
13
6
9400/3-C71.0
ICD-O-3
Astrocytoma, NOS, of cerebrum
+∞
9.5
9
*
183
Kela drug reimbursment
Lamotrigin and topiramate
14.8
9.4
15
11
AA1BD
NOMESCO Finland
Extensive CT of head and brain
16.8
9.2
14
9
H02AB09
ATC
hydrocortisone; systemic
11.7
9.0
16
15
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
52.8
8.8
10
*
H02AB04
ATC
methylprednisolone; systemic
3.7
8.6
30
93
G91.1
ICD-10 Finland
Obstructive hydrocephalus
94.7
8.5
9
*
N76
ICPC
Neoplasm nervous system unspecified
+∞
8.4
8
*
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
+∞
8.4
8
*
C71.00
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles without histology
+∞
8.4
8
*
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
15.5
8.4
13
9
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
23.4
8.1
11
5
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.4
7.9
32
109
ZXE30
NOMESCO Finland
More than five and less than seven hours
8.7
7.8
16
20
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
12.7
7.7
13
11
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
26.4
7.7
10
*
9400/3-C71.3
ICD-O-3
Astrocytoma, NOS, of parietal lobe
+∞
7.3
7
*
A79
ICPC
Malignancy NOS
+∞
7.3
7
*
C71.80
ICD-10 Finland
Overall malignant tumor of the brain without histology
+∞
7.3
7
*
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
41.8
6.8
8
*
R4130
NOMESCO Finland
Speech therapy
8.4
6.8
14
18
A28
ICPC
Limited function/disability NOS
3.3
6.7
28
97
R47.0
ICD-10 Finland
Dysphasia and aphasia
15.1
6.5
10
7
G40.89
ICD-10 Finland
Other epilepsy
72.5
6.5
7
*
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
72.5
6.5
7
*
R4110
NOMESCO Finland
Physiotherapy
2.5
6.5
50
242
N03AX09
ATC
lamotrigine; oral
3.9
6.4
20
57
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
18.9
6.3
9
5
C71.82
ICD-10 Finland
Overall malignant tumor of the brain grade III glioma
+∞
6.3
6
*
C71.32
ICD-10 Finland
Malignant tumor of parietal lobe grade III glioma
+∞
6.3
6
*
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
+∞
6.3
6
*
C71.40
ICD-10 Finland
Malignant tumor of the occipital lobe without histology
+∞
6.3
6
*
AA5NK
NOMESCO Finland
Tractography within white matter of central nervous system
+∞
6.3
6
*
C71.91
ICD-10 Finland
Malignant tumor in unspecified location in the brain grade II glioma
+∞
6.3
6
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.2
6.2
26
90
R4120
NOMESCO Finland
Occupational therapy
4.0
6.1
18
49
WX002
NOMESCO Finland
Sedation and analgesia
2.8
6.0
34
140

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
97
35
65.27
154.73
1.4
1.3
—
—
—
0
0
87
112
15.22
70.70
5.9
14.8
0.60
1.48
mmol/l
1.53
69
96
87
114
14.93
69.73
6.0
14.6
7.41
7.41
ph
0.04
59
57
64
72
13.84
55.89
4.8
9.6
23.91
25.42
mmol/l
2.37
64
72
131
576
7.04
27.74
7.4
6.7
1.20
1.21
mmol/l
1.25
119
510
106
426
5.12
23.86
2.3
1.9
—
—
—
0
0
111
469
5.13
23.27
3.4
1.6
—
—
—
0
0
123
613
4.89
19.55
2.9
2.6
—
—
estimate
—
0
0
26
36
8.38
18.36
2.0
1.2
—
—
—
0
0
25
20
14.49
14.97
2.1
1.4
—
—
—
0
0
97
466
3.60
14.86
4.0
9.0
1.01
1.14
inr
7.74
79
382
132
780
4.38
14.59
18.0
7.5
3.43
4.17
e9/l
4.47
114
676
93
439
3.54
14.58
10.7
6.3
—
—
—
0
0
82
359
3.54
14.47
9.3
2.0
2.38
2.35
mmol/l
1.70
77
322
39
104
4.59
13.96
6.9
10.2
—
—
—
0
0
22
19
13.15
12.76
2.0
1.2
—
—
—
0
0
23
42
6.20
12.51
2.0
1.2
975.06
48.34
e6/l
0.48
16
32
23
42
6.20
12.51
1.9
1.1
68.06
19.43
e6/l
0.59
16
30
25
51
5.59
12.12
5.4
14.6
—
—
—
0
0
117
711
3.19
10.80
10.8
6.5
0.53
0.55
e9/l
0.63
99
620
117
714
3.16
10.67
10.7
6.4
0.03
0.04
e9/l
6.00
98
622
119
738
3.16
10.45
10.9
6.8
0.12
0.20
e9/l
10.04
102
651
116
733
2.93
9.40
10.9
6.5
1.50
1.91
e9/l
7.26
98
651
89
492
2.74
9.35
4.5
4.1
36.96
37.42
g/l
0.36
84
466
109
668
2.84
9.34
11.0
6.5
60.16
56.64
%
2.08
109
650
83
454
2.66
8.75
1.3
1.6
—
—
—
0
0
59
286
2.65
7.78
3.5
3.8
—
—
—
0
0
113
1414
0.37
7.59
3.4
4.4
4.91
4.68
mmol/l
1.46
103
1352
113
1410
0.38
7.32
3.4
4.4
1.40
1.42
mmol/l
0.16
102
1344
66
348
2.49
7.22
2.8
2.8
7.40
7.40
ph
0.27
40
242
9
5
18.91
6.33
3.6
6.8
9.33
10.80
%
—
9
5
9
5
18.91
6.33
1.8
3.4
36.56
30.40
%
—
9
5
117
1422
0.40
6.27
3.5
4.8
3.04
2.82
mmol/l
1.87
105
1352
93
606
2.22
5.91
15.7
9.2
0.00
0.00
e9/l
0.44
70
487
12
20
6.38
5.01
1.8
1.2
—
—
—
0
0
110
1339
0.47
4.71
3.1
3.7
1.35
1.27
mmol/l
0.43
99
1262
106
1294
0.50
4.20
3.9
5.4
36.15
38.16
mmol/mol
3.02
95
1245
69
457
1.87
3.70
2.7
3.0
13.33
40.73
ng/l
1.80
46
255
111
1320
0.52
3.62
4.2
4.1
5.49
5.78
mmol/l
3.36
104
1237
59
386
1.82
3.21
9.5
4.9
—
—
—
0
0
48
308
1.79
2.73
2.4
2.5
—
—
—
0
0
45
658
0.57
2.68
2.1
2.7
—
—
—
0
0
19
355
0.48
2.46
3.3
3.7
26.22
53.99
mg/l
1.07
13
240
20
100
2.14
2.32
4.3
4.7
1.60
0.61
%
—
10
18
20
360
0.49
2.31
3.6
4.4
4.83
7.62
mg/mmol
0.34
12
239
0
59
0.00
2.30
0.0
1.1
—
—
—
0
0
52
357
1.66
2.29
4.7
2.9
—
—
—
0
0
7
18
4.01
2.28
3.1
2.4
5.19
4.88
kpa
—
7
18
7
18
4.01
2.28
3.1
2.4
2.27
2.09
mmol/l
—
7
12
7
18
4.01
2.28
3.1
2.4
8.81
8.39
kpa
—
7
18
151
1589
0.45
1.99
40.7
17.4
135.83
139.54
g/l
2.67
151
1575
5
11
4.65
1.95
1.4
1.4
93.04
90.94
%
—
5
11
151
1588
0.46
1.93
39.5
17.3
30.50
30.22
pg
1.29
151
1575
151
1588
0.46
1.93
39.6
17.3
4.51
4.64
e12/l
2.75
151
1559
151
1588
0.46
1.93
40.4
17.8
40.44
41.55
%
3.00
151
1574
151
1588
0.46
1.93
39.5
17.4
6.50
6.68
e9/l
0.47
151
1560
151
1587
0.46
1.87
39.7
17.3
90.69
90.16
fl
0.84
151
1574
151
1586
0.47
1.81
39.5
17.4
246.44
252.82
e9/l
0.35
151
1562
31
203
1.65
1.61
2.8
2.5
4.28
2.43
e6/l
0.29
16
85
7
26
2.76
1.60
3.1
3.2
7.43
7.41
ph
—
7
26
6
20
3.07
1.59
1.3
1.9
19.20
17.15
%
—
6
20
6
20
3.07
1.59
2.8
2.7
—
—
—
0
0
8
166
0.46
1.58
1.0
1.2
—
—
—
0
0
151
1398
1.89
1.55
25.4
12.6
3.90
3.95
mmol/l
1.75
151
1366
19
109
1.84
1.54
1.2
1.3
—
27.06
—
0
7
151
1399
1.88
1.53
26.1
12.5
139.23
139.74
mmol/l
1.36
151
1371
27
176
1.64
1.43
1.3
1.6
—
—
—
0
0
17
97
1.84
1.41
4.0
4.8
0.14
0.07
%
—
7
14
97
827
1.42
1.38
3.9
3.9
—
47.90
—
0
10
35
246
1.54
1.36
2.1
3.3
28.27
732.14
ng/l
0.87
15
153
0
39
0.00
1.35
0.0
1.1
—
—
—
0
0
19
292
0.61
1.24
1.7
1.5
—
—
—
0
0
46
350
1.43
1.22
2.5
2.5
0.14
0.23
e6/l
0.52
32
248
14
231
0.57
1.20
1.2
1.3
—
—
—
0
0
0
33
0.00
1.17
0.0
3.0
—
62.64
—
0
33
10
181
0.52
1.17
1.1
1.3
—
—
—
0
0
120
1302
0.72
1.07
4.3
5.0
1.57
1.76
mu/l
1.56
113
1227
5
109
0.44
1.05
1.0
1.2
—
—
—
0
0
10
54
1.91
0.99
2.4
1.7
20.40
20.17
s
—
10
47
26
352
0.69
0.94
1.1
1.4
1.73
2.34
g/l
2.53
12
217
43
338
1.37
0.94
7.0
4.5
—
—
—
0
0
48
585
0.75
0.91
3.1
2.9
6.34
6.19
ph
0.41
32
342
21
294
0.67
0.91
1.3
2.0
—
—
—
0
0
15
97
1.60
0.84
4.1
4.8
1.10
0.35
%
—
5
20
10
162
0.59
0.82
1.4
1.5
—
—
—
0
0
149
1418
1.50
0.80
23.7
11.3
19.59
21.92
mg/l
0.55
141
1106
61
708
0.78
0.78
2.5
3.1
89.21
87.91
ug/l
0.03
55
677
9
56
1.64
0.74
1.1
1.3
—
—
—
0
0
9
146
0.59
0.73
1.1
1.4
—
—
—
0
0
7
117
0.58
0.71
1.1
1.1
—
—
—
0
0
7
41
1.74
0.71
1.6
1.1
—
—
—
0
0
7
41
1.74
0.71
1.6
1.1
—
—
—
0
0
15
102
1.52
0.70
4.1
5.3
0.00
0.00
%
—
5
16
12
78
1.58
0.67
1.8
1.9
—
—
—
0
0
15
211
0.68
0.67
2.2
2.5
0.61
0.77
ug/l
—
8
108
29
362
0.76
0.64
3.1
3.3
0.00
0.00
estimate
—
10
131
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
12
172
0.67
0.60
2.2
2.0
—
—
—
0
0
0
22
0.00
0.60
0.0
1.1
—
—
—
0
0
48
408
1.25
0.59
2.6
2.5
22.38
215.87
e6/l
0.62
34
302
44
371
1.25
0.58
1.5
1.8
—
—
—
0
0
5
86
0.57
0.58
1.8
1.9
—
—
—
0
0
5
86
0.57
0.58
1.0
1.2
—
—
—
0
0
6
36
1.69
0.57
2.5
10.4
—
—
—
0
0
8
123
0.63
0.57
2.0
1.6
—
—
—
0
0
9
64
1.43
0.52
1.3
3.0
7.44
7.41
ph
—
9
53
63
702
0.83
0.50
3.3
3.2
0.00
0.00
estimate
-0.00
12
136
8
118
0.66
0.47
2.0
1.6
—
—
—
0
0
65
718
0.84
0.46
3.3
3.3
0.00
0.00
estimate
-0.00
12
128
36
419
0.82
0.44
3.2
2.6
0.00
0.00
estimate
—
10
114
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
75.06
—
0
16
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
2.6
—
—
—
0
0
146
1500
0.78
0.41
20.6
9.8
—
—
—
0
0
18
142
1.30
0.40
1.1
1.2
—
—
—
0
0
65
712
0.86
0.40
3.1
3.2
0.00
0.00
estimate
-0.00
12
136
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
12.36
—
0
18
9
124
0.71
0.36
1.9
1.6
—
—
—
0
0
9
125
0.70
0.36
1.9
1.6
—
—
—
0
0
9
125
0.70
0.36
1.8
1.6
—
—
—
0
0
6
43
1.41
0.35
1.5
2.8
—
—
—
0
0
19
155
1.25
0.34
1.8
1.6
1267.80
1091.98
nmol/l
—
10
123
30
258
1.20
0.34
1.4
1.7
—
—
—
0
0
101
1063
0.87
0.33
3.8
4.3
14.23
14.58
pmol/l
0.72
94
999
14
175
0.78
0.32
1.1
2.2
—
—
—
0
0
50
550
0.87
0.32
3.3
2.9
0.00
0.00
estimate
-0.00
11
119
11
85
1.31
0.29
2.3
2.3
62.86
72.35
e9/l
—
5
55
9
72
1.26
0.26
1.1
1.2
—
—
—
0
0
6
81
0.73
0.24
1.2
1.7
—
—
—
0
0
7
94
0.73
0.23
3.9
1.8
0.06
0.19
e6/l
—
7
87
43
468
0.89
0.23
1.8
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
4.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
153.46
—
0
12
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
6
49
1.23
0.20
1.0
1.1
—
—
—
0
0
29
321
0.88
0.20
2.8
2.9
1.02
1.02
kg/l
0.66
19
210
121
1242
0.90
0.19
32.6
14.0
13.34
13.28
%
0.24
121
1228
36
331
1.11
0.18
1.4
1.5
17.37
20.67
nmol/l
0.83
31
295
50
530
0.92
0.16
1.7
1.9
93.19
99.54
pmol/l
0.46
27
273
6
79
0.75
0.16
1.2
1.5
—
—
—
0
0
6
80
0.74
0.16
1.0
1.1
1.43
1.47
g/l
—
6
80
6
80
0.74
0.16
1.0
1.1
0.78
0.90
g/l
—
6
80
8
97
0.82
0.14
1.9
1.5
—
—
—
0
0
11
128
0.85
0.14
1.6
2.9
6.05
5.74
kpa
0.57
11
123
12
135
0.88
0.10
1.3
1.1
—
—
—
0
0
150
1515
0.90
0.09
20.7
9.1
29.21
28.27
u/l
0.23
150
1481
6
74
0.80
0.07
1.3
2.9
25.33
24.44
mmol/l
—
6
74
9
85
1.06
0.07
1.7
2.3
8.77
9.75
ug/l
—
9
75
9
103
0.87
0.06
3.0
2.9
—
—
—
0
0
50
486
1.04
0.05
3.1
3.3
46.92
50.74
e6/l
0.04
34
327
30
310
0.96
0.03
2.0
2.1
1.84
2.56
mg/l
2.47
24
272
31
311
1.00
0.00
1.5
1.7
1.19
0.86
mg/l
0.32
22
234
17
175
0.97
0.00
2.1
2.5
10.42
6.11
umol/l
0.27
12
156
16
158
1.01
0.00
1.3
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
6.0
—
9.95
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
195.00
—
0
9
5
52
0.96
0.00
1.2
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
11.82
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
1999.00
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.0
—
4.02
—
0
5
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
26.83
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
57.00
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
151
1510
1.00
-0.00
30.4
13.3
69.56
75.21
umol/l
3.25
151
1492
7
74
0.94
-0.00
3.9
3.5
67.29
81.82
ng/l
—
7
64
0
8
0.00
-0.00
0.0
1.0
—
293.25
—
0
8
5
59
0.84
-0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
13.08
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_ASTROCYTOMA – Brain astrocytoma

GWS hits: 1

This endpoint is excluded from FinRegistry analyses (omitted endpoint).