Graves disease: Graves' disease is an autoimmune disorder that leads to overactivity of the thyroid gland ( hyperthyroidism ).It is caused by an abnormal immune system response that causes the thyroid gland to produce too much thyroid hormones. Graves disease is the most common cause of hyperthyroidism andoccurs mostoften in women over age 20. However, the disorder may occur at any age and may affect males as well.Treatmentmayinclude radioiodine therapy , antithyroid drugs, and/or thyroid surgery.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
7162 |
4. Check minimum number of eventsNone |
7162 |
5. Include endpointsNone |
7162 |
6. Filter based on genotype QC (FinnGen only) |
6494 |
Control definitions (FinnGen only)
- Control exclude
- E4_THYROID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E05
- Name in latin
- Thyreotoxicosis cum struma diffusa
Similar endpoints
↥List of similar endpoints to
Thyrotoxicosis with diffuse goitre
based on the number of shared cases.
Similar with more cases:
- Thyrotoxicosis
- Disorders of thyroid, IBD co-morbidities
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
- Endocrine, nutritional and metabolic diseases
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 38371 | 31186 | 6900 |
| Only index persons | 35764 | 29429 | 6335 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.76 | 0.89 | 0.19 |
| Only index persons | 0.93 | 1.08 | 0.24 |
| Median age at first event (years) | |||
| Whole population | 49.44 | 49.13 | 51.36 |
| Only index persons | 48.69 | 48.33 | 50.36 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 6494 | 5438 | 1056 |
| Unadjusted period prevalence (%) | 1.70 | 1.93 | 0.48 |
| Median age at first event (years) | 50.31 | 49.23 | 55.86 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 6754
- Matched controls
- 67540
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
T86
ICPC
Hypothyroidism/myxoedema
125.5
307.7
817
74
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
5776.7
307.7
543
*
E03.89
ICD-10 Finland
Other specified hypothyroidism
167.0
307.7
717
48
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
2422.2
307.7
2902
21
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
11069.6
307.7
963
*
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
1301.1
307.7
594
5
C07AA05
ATC
propranolol; systemic
4.6
307.7
2835
9158
104
Kela drug reimbursment
Thyroid insufficiency
1900.4
307.7
1909
14
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
34.6
307.7
521
163
H03AA01
ATC
levothyroxine sodium; systemic
193.7
307.7
4825
861
T85
ICPC
Hyperthyroidism/thyrotoxicosis
191.7
307.7
414
23
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
213.8
307.7
267
13
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
154.9
307.7
1791
157
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
26.3
307.7
381
153
BAA60
NOMESCO Finland
Total thyroidectomy
16384.0
307.7
1440
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.5
307.7
736
1460
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
12739.1
307.7
1084
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
307.7
755
*
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
74.9
307.7
287
40
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
4503599627370496.0
307.7
6286
*
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
362.7
307.7
1069
35
H03BB01
ATC
carbimazole; oral
5546.8
307.7
5566
57
E03
ICD-10 Finland
Other hypothyroidism
111.6
307.7
798
81
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
27.0
307.7
285
110
C07AB07
ATC
bisoprolol; oral
2.5
303.1
3564
20591
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
2876.4
297.8
286
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
32.8
274.0
176
55
H062, E050,
ICD-10 Finland
+∞
227.4
217
*
E06.3
ICD-10 Finland
Autoimmune thyroiditis
37.6
226.6
140
38
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
216.8
207
*
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
13.2
215.6
206
160
24209
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffuse NUD
+∞
202.1
193
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
202.0
2725
15895
E05.89
ICD-10 Finland
Other thyrotoxicosis
+∞
201.0
192
*
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
12.4
189.7
189
157
2420A
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic diffuse goitre
+∞
183.1
175
*
H05.2
ICD-10 Finland
Exophthalmic conditions
34.1
179.6
114
34
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
26.0
173.1
120
47
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
161.2
3334
22231
24200
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffusa et exophthalmo. Morbus Basedowi
+∞
157.9
151
*
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
1498.4
148.4
144
*
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
43.0
142.3
85
20
106
Kela drug reimbursment
Hypoparathyroidism
65.7
142.0
78
12
H03BA02
ATC
propylthiouracil; oral
+∞
141.1
135
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
10.3
137.7
154
152
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
162.3
135.9
143
9
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.1
130.3
373
949
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
1272.5
128.6
125
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
1272.5
128.6
125
*
CA1AD
NOMESCO Finland
Orbita CT
26.2
120.2
83
32
A11CC03
ATC
alfacalcidol; systemic
5.8
116.6
217
385
E06.9
ICD-10 Finland
Thyroiditis, unspecified
48.9
108.4
63
13
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
106.5
102
*
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
13.5
102.3
96
72
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
6.1
98.9
173
289
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
170.9
96.5
101
6
E83.51
ICD-10 Finland
Hypocalcemia
12.4
95.0
94
77
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
40.3
92.1
56
14
E05.5
ICD-10 Finland
Thyroid crisis or storm
+∞
83.5
80
*
H50.2
ICD-10 Finland
Vertical strabismus
7.2
74.8
111
156
H53.2
ICD-10 Finland
Diplopia
3.4
71.2
265
804
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
+∞
70.9
68
*
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
65.7
63
*
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
+∞
62.6
60
*
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
15.0
62.2
55
37
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.0
60.9
286
996
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
+∞
60.5
58
*
H02AB06
ATC
prednisolone; systemic
1.5
59.1
3073
23959
H50.8
ICD-10 Finland
Other specified strabismus
17.1
55.7
46
27
A11CC02
ATC
dihydrotachysterol; oral
21.7
55.1
41
19
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.5
54.4
352
1444
C07AB02
ATC
metoprolol; systemic
1.7
54.0
1087
6743
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
53.9
1145
7208
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
+∞
53.2
51
*
R00.2
ICD-10 Finland
Palpitations
2.0
53.0
643
3405
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.3
52.6
198
605
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
267.9
52.2
53
*
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
501.7
50.5
50
*
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
49.5
906
5460
T89
ICPC
Diabetes insulin dependent
2.7
48.7
265
998
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
6.9
47.8
74
109
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.9
47.3
650
3585
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
7.4
46.6
67
91
ZXA10
NOMESCO Finland
Bilateral
1.7
45.9
1101
7125
H04AA01
ATC
glucagon; nasal, parenteral
3.3
43.6
163
496
H02AB09
ATC
hydrocortisone; systemic
3.4
42.5
157
474
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.7
41.0
894
5631
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
40.3
2128
16280
WX402
NOMESCO Finland
General anaesthesia
1.5
40.1
1473
10486
H50.6
ICD-10 Finland
Mechanical strabismus
66.1
40.1
46
7
XCK00
NOMESCO Finland
Perimetry
2.1
39.9
389
1897
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.3
37.9
146
453
TFP20
NOMESCO Finland
Cardiodefibrillation
2.2
37.6
330
1545
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
+∞
37.5
36
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
36.9
1518
11035
24210
ICD-8 Finland
Thyrotoxicosis with or without goitre, Toxic nodular goitre
49.2
36.6
44
9
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
359.3
36.0
36
*
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
10.3
36.0
40
39
C01BD01
ATC
amiodarone; systemic
3.2
35.8
140
438
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
35.7
2637
21288
BA1AE, ,
SPAT
3.8
35.7
110
295
R06.0
ICD-10 Finland
Dyspnoea
1.5
35.3
1563
11513
R53
ICD-10 Finland
Malaise and fatigue
1.5
34.7
1607
11934
A10AB01
ATC
insulin (human); parenteral
2.6
34.5
202
789
24220
ICD-8 Finland
Thyrotoxicosis with or without goitre, Thyrotoxicosis without mention of goitre
+∞
34.4
33
*
A10AB04
ATC
insulin lispro; parenteral
2.6
33.8
192
739
CAC44
NOMESCO Finland
Combined decompression of orbit
170.8
32.7
34
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
32.3
1272
9131
CEC00
NOMESCO Finland
Recession of extraocular muscle
6.2
32.1
54
87
C07AA07
ATC
sotalol; systemic
2.7
31.8
171
641
H02AB07
ATC
prednisone; oral
1.6
31.1
807
5287
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
314.4
30.8
31
*
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
10.7
30.4
33
31
K90.0
ICD-10 Finland
Coeliac disease
2.4
30.2
204
854
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
30.0
1256
9110
H3600, E103,
ICD-10 Finland
4.2
29.3
77
184
A10AA01, ,
ATC
2.7
29.0
154
573
A10AB05
ATC
insulin aspart; parenteral
1.9
28.7
382
2078
K04
ICPC
Palpitations/awareness of heart
1.9
28.6
367
1973
207
Kela drug reimbursment
Chronic arrhythmias
1.6
27.8
674
4339
CAC20
NOMESCO Finland
Lateral decompression of orbit
145.6
27.6
29
*
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
9.2
27.4
33
36
A10AA02, ,
ATC
2.5
27.2
171
693
ZX120
NOMESCO Finland
Intravenous
1.7
27.1
530
3230
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.7
26.3
146
556
K29.4
ICD-10 Finland
Chronic atrophic gastritis
3.0
26.3
113
375
A10AC01
ATC
insulin (human); parenteral
1.8
26.1
370
2054
E05.3
ICD-10 Finland
Thyrotoxicosis from ectopic thyroid tissue
+∞
26.1
25
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
26.0
2337
19179
A04
ICPC
Weakness/tiredness general
1.5
25.9
958
6765
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
25.8
1608
12472
A02BC02
ATC
pantoprazole; systemic
1.3
25.7
4278
38236
A10AE05
ATC
insulin detemir; parenteral
2.1
25.6
261
1295
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.6
25.5
689
4548
B03BA03
ATC
hydroxocobalamin; parenteral
2.0
25.3
261
1301
C03CA01
ATC
furosemide; systemic
1.4
25.2
1325
9985
N02BE01
ATC
paracetamol; systemic, rectal
1.5
25.0
5860
55131
T81
ICPC
Goitre
8.5
24.9
32
38
107
Kela drug reimbursment
Pernicious anaemia
3.2
24.5
95
297
K80
ICPC
Cardiac arrhythmia NOS
1.7
24.3
514
3195
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
7.3
24.1
35
48
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.9
24.1
115
405
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.6
23.3
621
4082
A10AE04
ATC
insulin glargine; parenteral
1.7
23.2
442
2673
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
+∞
22.9
22
*
E05.81
ICD-10 Finland
Overproduction of thyroid-stimulating hormone
+∞
22.9
22
*
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.7
22.8
411
2447
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.7
22.7
119
441
XCK10
NOMESCO Finland
Photography of fundus of eye
1.7
22.1
451
2778
2AB04, ,
NOMESCO Finland
6.5
21.7
35
54
A10AE06
ATC
insulin degludec; parenteral
2.2
21.6
187
871
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
21.2
533
3453
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
21.2
1117
8396
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
21.1
2161
17933
E89.9
ICD-10 Finland
Postprocedural endocrine and metabolic disorder, unspecified
+∞
20.8
20
*
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
77.0
20.7
23
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
20.6
761
5356
SPAT1097
SPAT
Recording of ECG
1.5
20.4
702
4874
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.4
20.0
845
6102
H3601, E103,
ICD-10 Finland
3.9
19.8
58
151
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
19.7
1849
15130
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
3.8
19.7
59
156
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
2.7
19.4
104
390
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
3.1
19.0
78
253
WF099
NOMESCO Finland
Other radiotherapy
4.2
19.0
49
116
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.4
18.9
772
5537
G73.0*E05.9
ICD-10 Finland
Myasthenic syndromes in thyrotoxicosis [hyperthyroidism]
+∞
18.8
18
*
E06.4
ICD-10 Finland
Drug-induced thyroiditis
+∞
18.8
18
*
8341/3-C73.9
ICD-O-3
Papillary microcarcinoma of thyroid gland
+∞
18.8
18
*
E20.8
ICD-10 Finland
Other hypoparathyroidism
70.1
18.7
21
*
E06.0
ICD-10 Finland
Acute thyroiditis
27.9
18.7
25
9
E07.89
ICD-10 Finland
Other specified disorders of thyroid
20.8
18.6
27
13
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
18.4
4600
42273
E89.1
ICD-10 Finland
Postprocedural hypoinsulinaemia
44.1
18.2
22
5
H50.0
ICD-10 Finland
Convergent concomitant strabismus
3.7
17.9
57
157
Z3231
NOMESCO Finland
Registered nurse
1.3
17.7
1448
11601
M14.5*E03.9
ICD-10 Finland
Arthropathy in hypothyroidism (E00-E03+)
+∞
17.7
17
*
B01AA03
ATC
warfarin; systemic
1.4
17.7
709
5066
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
17.6
1482
11919
2504
FHL
Unilateral resection or enucleation
36.8
17.6
22
6
ZXE00
NOMESCO Finland
One hour or less
1.3
17.5
2253
19131
B81
ICPC
Anaemia vit B12/folate deficiency
2.1
17.3
168
821
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
17.2
1024
7827
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.5
17.1
481
3196
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
4.3
17.1
44
104
A60
ICPC
General and Unspecified, Result test/procedure
1.8
17.0
238
1317
N05CF01
ATC
zopiclone; oral
1.3
17.0
1730
14259
CEW99
NOMESCO Finland
Other operation on extraocular muscle
19.3
16.8
25
13
Z01.7
ICD-10 Finland
Laboratory examination
1.4
16.7
974
7415
R03AC02
ATC
salbutamol; inhalant
1.2
16.6
3435
30703
O90.5
ICD-10 Finland
Postpartum thyroiditis
90.3
16.6
18
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
90.3
16.6
18
*
E50.0
ICD-10 Finland
Vitamin A deficiency with conjunctival xerosis
170.4
16.5
17
*
CA1BD
NOMESCO Finland
Extensive orbita CT
23.1
16.4
23
10
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
16.2
1281
10199
C01AA05
ATC
digoxin; systemic
1.7
16.2
277
1626
SPAT1262
SPAT
Handing over of treatment supplies
1.4
16.2
776
5721
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
15.3
16.1
26
17
A12AA04
ATC
calcium carbonate; oral
2.9
16.1
72
246
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
3.6
16.1
53
150
B01AF02
ATC
apixaban; oral
1.5
15.8
571
3995
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
3.2
15.8
61
191
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.7
15.7
314
1924
105
Kela drug reimbursment
Adrenal cortical hypofunction
12.9
15.6
27
21
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.7
15.6
294
1773
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.6
15.3
329
2054
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
15.2
2284
19658
J01DB01
ATC
cefalexin; oral
1.3
15.1
5263
49568
177
Kela drug reimbursment
Insulin glargine 300 U / ml
2.5
15.1
92
369
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.6
14.9
318
1980
E03.4
ICD-10 Finland
Atrophy of thyroid (acquired)
+∞
14.6
14
*
R63.4
ICD-10 Finland
Abnormal weight loss
1.8
14.6
202
1115
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
3.6
14.5
46
127
D51.0
ICD-10 Finland
Vitamin B12deficiency anaemia due to intrinsic factor deficiency
4.6
14.4
34
75
SPAT1263
SPAT
Sampling
1.2
14.4
2383
20694
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
3.9
13.9
40
103
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
13.7
1621
13550
M14.5*E05.9
ICD-10 Finland
Arthropathy in thyrotoxicosis [hyperthyroidism]
+∞
13.5
13
*
E03.8
ICD-10 Finland
Other specified hypothyroidism
+∞
13.5
13
*
24400
ICD-8 Finland
Myxoedema, (hypothyreosis) post therapiam
+∞
13.5
13
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.8
13.5
214
1230
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.3
13.5
1613
13490
GB1AA
NOMESCO Finland
Tracheal X-ray examination
140.3
13.4
14
*
H36.00
ICD-10 Finland
Diabetic background retinopathy
2.7
13.4
68
249
CE2W4
NOMESCO Finland
Eye movement mapping
6.3
13.3
22
35
A02BC01
ATC
omeprazole; systemic
1.3
13.2
1445
11955
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
13.2
3409
30860
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
3.3
13.1
49
151
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
10.0
12.9
25
25
G47.3
ICD-10 Finland
Sleep apnoea
1.3
12.9
1089
8722
XF404
NOMESCO Finland
Ambulatory ECG
1.5
12.9
393
2658
R60.9
ICD-10 Finland
Oedema, unspecified
1.6
12.8
295
1873
F29
ICPC
Eye symptom/complaint other
1.4
12.8
617
4548
K02.1
ICD-10 Finland
Caries of dentine
1.2
12.7
3680
33623
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
2.5
12.7
76
303
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
12.7
1074
8605
J01AA02
ATC
doxycycline; systemic
1.2
12.6
4849
45532
6481B
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Thyroid dysfunction[HYPOTHYREOSIS IN GRAVIDITATE]
70.0
12.6
14
*
R01AD08
ATC
fluticasone; nasal
1.2
12.6
1708
14473
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
2.7
12.6
65
241
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
4.6
12.6
29
63
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
+∞
12.5
12
*
O992, E050,
ICD-10 Finland
+∞
12.5
12
*
E89
ICD-10 Finland
Postprocedural endocrine and metabolic disorders, not elsewhere classified
+∞
12.5
12
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.3
12.4
837
6499
EP1AE, ,
SPAT
1.9
12.3
147
776
A29
ICPC
General symptom/complaint other
1.4
12.2
699
5299
R02
ICPC
Shortness of breath/dyspnoea
1.4
12.1
700
5310
L28
ICPC
Limited function/disability (L)
1.3
12.1
926
7315
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
12.0
1039
8340
R25.1
ICD-10 Finland
Tremor, unspecified
1.9
12.0
149
796
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.5
12.0
367
2486
N07BA03
ATC
varenicline; oral
1.6
11.9
268
1693
N02AX02
ATC
tramadol; systemic, rectal
1.2
11.9
2329
20465
A02BC05
ATC
esomeprazole; systemic
1.2
11.9
2328
20457
Z71.8
ICD-10 Finland
Other specified counselling
1.2
11.8
2087
18151
WZC30
NOMESCO Finland
Teaching
1.3
11.8
842
6590
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.3
11.7
1053
8495
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.5
11.7
383
2629
R49.08
ICD-10 Finland
Other specified dysphonia
2.0
11.7
129
663
XF600
NOMESCO Finland
Bloodpressure measurement
1.6
11.6
282
1815
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.4
11.5
526
3840
A09
ICPC
Sweating problem
2.4
11.5
77
324
8340/3-C73.9
ICD-O-3
Papillary carcinoma, follicular variant of thyroid gland
+∞
11.5
11
*
A99
ICPC
Disease/condition unspecnature/site
1.4
11.5
544
3998
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
2.4
11.4
79
338
N05CF02
ATC
zolpidem; oral
1.3
11.3
986
7918
TFP34
NOMESCO Finland
Electrophysiological investigation
1.9
11.3
147
797
CKC12
NOMESCO Finland
Photocoagulation of retina
1.7
11.3
189
1105
E04.8
ICD-10 Finland
Other specified nontoxic goitre
11.8
11.3
20
17
M54.5
ICD-10 Finland
Low back pain
1.2
11.2
2233
19619
N05BA04
ATC
oxazepam; oral
1.2
11.2
1480
12476
R21
ICPC
Throat symptom/complaint
1.2
11.2
1331
11093
K78
ICPC
Atrial fibrillation/flutter
1.6
11.2
282
1830
I48.1
ICD-10 Finland
Persistent atrial fibrillation
1.8
11.2
166
938
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
11.1
1561
13245
BAA20
NOMESCO Finland
Unilateral partial excision of thyroid gland
25.0
11.1
15
6
WX290
NOMESCO Finland
Other blockage of nerve
1.2
11.1
2941
26521
N06AX21
ATC
duloxetine; oral
1.3
11.1
672
5133
W84
ICPC
Pregnancy high risk
1.7
11.0
200
1196
C01BC04
ATC
flecainide; systemic
1.8
11.0
151
833
J01FA10
ATC
azithromycin; systemic
1.2
11.0
3616
33226
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
10.9
3330
30381
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
10.9
2517
22404
M79.6
ICD-10 Finland
Pain in limb
1.2
10.9
2697
24156
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
10.9
630
4780
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
2.8
10.8
52
186
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.4
10.8
402
2829
C10AX09
ATC
ezetimibe; oral
1.3
10.8
741
5764
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
10.8
1115
9143
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
10.7
590
4439
C10AA07
ATC
rosuvastatin; oral
1.2
10.7
1735
14932
XF400
NOMESCO Finland
ECG with 12 standard connections
1.3
10.7
654
5001
SGA01
NOMESCO Finland
Emergency treatment
1.3
10.7
944
7591
ZYC06
NOMESCO Finland
Real-time text-based remote transaction
4.6
10.7
25
55
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.0
10.7
106
525
B01AB05
ATC
enoxaparin; parenteral
1.2
10.7
1669
14314
A91
ICPC
Abnormal result investigation NOS
1.6
10.6
268
1740
CS494
NOMESCO Finland
Other visual field testing
1.9
10.6
121
629
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
1.7
10.6
170
983
M03BX02
ATC
tizanidine; oral
1.2
10.5
3893
36066
H03BB02
ATC
thiamazole; oral
110.2
10.4
11
*
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
110.2
10.4
11
*
TBA20
NOMESCO Finland
Aspiration cytology of thyroid gland
+∞
10.4
10
*
N06AX11
ATC
mirtazapine; oral
1.2
10.4
1944
16954
WZC00
NOMESCO Finland
Treatment plan or consultation
1.2
10.3
2105
18505
C03DA01
ATC
spironolactone; oral
1.4
10.3
508
3757
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
10.3
2368
21047
E20.9
ICD-10 Finland
Hypoparathyroidism, unspecified
18.8
10.2
15
8
R50.9
ICD-10 Finland
Fever, unspecified
1.3
10.1
752
5911
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
1.6
10.1
221
1388
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.3
10.1
717
5602
G44.2
ICD-10 Finland
Tension-type headache
1.3
10.0
831
6627
103
Kela drug reimbursment
Diabetes, insulin-treated
1.3
10.0
1111
9180
L04
ICPC
Chest symptom/complaint
1.5
9.9
347
2415
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
1.8
9.9
139
774
R4110, ,
SPAT
1.3
9.9
719
5636
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.0
9.7
108
557
T99
ICPC
Endocr/metab/nutrit disease other
2.2
9.7
80
369
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.4
9.7
401
2879
R06AE07
ATC
cetirizine; oral
1.2
9.7
2735
24705
BWD00
NOMESCO Finland
Reoperation for deep haemorrhage in endocrine surgery
55.1
9.6
11
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.3
9.6
588
4495
A08
ICPC
Swelling
1.5
9.6
274
1829
J01CA04
ATC
amoxicillin; systemic
1.2
9.6
5228
49889
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.2
9.6
1722
14942
D01
ICPC
Abdominal pain/cramps general
1.3
9.6
720
5669
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.3
9.6
688
5384
I47.2
ICD-10 Finland
Ventricular tachycardia
2.2
9.5
76
346
BEF00, ,
SPAT
3.0
9.5
40
133
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
1.7
9.5
170
1016
D06
ICPC
Abdominal pain localized other
1.4
9.5
531
4009
J01FA09
ATC
clarithromycin; systemic
1.2
9.4
1809
15787
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
9.4
1452
12410
OAB50, ,
SPAT
1.4
9.4
362
2564
C73.92
ICD-10 Finland
Follicular carcinoma of the thyroid gland
100.2
9.4
10
*
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
100.2
9.4
10
*
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
2.9
9.4
43
150
E05.8
ICD-10 Finland
Other thyrotoxicosis
+∞
9.4
9
*
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
+∞
9.4
9
*
24110
ICD-8 Finland
Non-toxic nodular goitre, Sporadic
+∞
9.4
9
*
4CJ01, ,
NOMESCO Finland
+∞
9.4
9
*
2506
FHL
Thyroidectomy
+∞
9.4
9
*
JN5AQ
NOMESCO Finland
SPECT of thyroid metastasis with low-dose CT
+∞
9.4
9
*
R51.80
ICD-10 Finland
Headache
1.3
9.4
918
7471
R60.0
ICD-10 Finland
Localized oedema
1.3
9.4
619
4788
R05
ICPC
Cough
1.2
9.3
1462
12515
R01AD09
ATC
mometasone; nasal
1.2
9.3
2815
25543
SPAT1301
SPAT
No procedures
1.2
9.2
1591
13745
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
9.2
2480
22286
R42
ICD-10 Finland
Dizziness and giddiness
1.2
9.2
1207
10152
XCH00
NOMESCO Finland
Eye pressure measurement
1.6
9.1
226
1463
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.2
9.1
1222
10294
-60
ICPC
Result test/procedure
1.5
9.1
271
1826
E23.05
ICD-10 Finland
Lack of TSH
15.6
9.0
14
9
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
9.0
2787
25312
A98
ICPC
Health maint/preventive medicine
1.5
9.0
6498
63787
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
24.0
8.9
12
5
TFP47
NOMESCO Finland
Ablation or modification of the AV-node
3.4
8.9
31
92
M25.5
ICD-10 Finland
Pain in joint
1.2
8.9
2018
17864
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.5
8.8
312
2176
A06AC01
ATC
ispaghula (psylla seeds); oral
1.2
8.8
1409
12077
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
8.8
4573
43235
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
1.8
8.8
137
789
J02AC01
ATC
fluconazole; systemic
1.2
8.7
2687
24372
L04AA06
ATC
mycophenolic acid; systemic
2.0
8.7
96
495
C10AA05
ATC
atorvastatin; oral
1.2
8.7
1928
17021
S06.0
ICD-10 Finland
Concussion
1.3
8.7
533
4079
E06.5
ICD-10 Finland
Other chronic thyroiditis
50.1
8.7
10
*
J01FA06
ATC
roxithromycin; oral
1.2
8.6
2252
20151
A27
ICPC
Fear of other disease NOS
1.5
8.6
249
1670
H02AA02
ATC
fludrocortisone; oral
3.0
8.6
37
125
AA1AD
NOMESCO Finland
CT of head and brain
1.2
8.5
1328
11359
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
8.4
1986
17613
D07AD01
ATC
clobetasol; topical
1.2
8.4
902
7416
H36.01
ICD-10 Finland
Diabetic maculopathy
2.4
8.4
54
225
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.6
8.4
185
1168
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
2.8
8.4
41
149
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
4.5
8.4
20
45
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.2
8.3
1492
12916
2441A
ICD-9 Finland
Acquired hypothyroidism, Other postablative hypothyroidism
+∞
8.3
8
*
3762A
ICD-9 Finland
Disorders of the orbit, Endocrine exophthalmos
+∞
8.3
8
*
BA1AN
NOMESCO Finland
Thyroid gland isotope imaging
+∞
8.3
8
*
D11
ICPC
Diarrhoea
1.3
8.3
688
5485
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.2
8.3
1440
12433
SPAT1310
SPAT
Counselling related to known health issue
1.2
8.3
1645
14376
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.4
8.3
347
2500
H57.1
ICD-10 Finland
Ocular pain
1.5
8.3
224
1482
R11
ICD-10 Finland
Nausea and vomiting
1.4
8.2
456
3436
XF402
NOMESCO Finland
ECG with work load test
1.4
8.2
413
3065
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.5
8.2
232
1548
N03AX12
ATC
[U] gabapentin; oral
1.3
8.2
810
6594
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.3
8.2
510
3912
SPAT1377
SPAT
Polysomnography
1.7
8.1
146
874
A50
ICPC
General and Unspecified, Medication/prescr/renewal
1.6
8.1
185
1176
F01
ICPC
Eye pain
1.6
8.1
164
1013
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
2.3
8.1
60
266
T71
ICPC
Malignant neoplasm thyroid
33.4
8.1
10
*
L17
ICPC
Foot/toe symptom/complaint
1.2
8.1
1716
15080
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
8.0
2095
18719
SFA20
NOMESCO Finland
Two-surface restoration
1.2
8.0
3617
33697
T08
ICPC
Weight loss
2.0
8.0
83
420
J01FF01
ATC
clindamycin; systemic
1.2
8.0
1416
12246
R5140
NOMESCO Finland
Monitoring the use of the aid
1.3
8.0
462
3507
I50.0
ICD-10 Finland
Congestive heart failure
1.5
8.0
230
1543
SPAT1312
SPAT
General health counselling
1.2
7.9
1679
14744
AQ2
HP
Electrophysiological electroanatomical examination
3.7
7.9
24
65
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.3
7.8
660
5272
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
2.6
7.8
42
161
J45.9
ICD-10 Finland
Asthma, unspecified
1.2
7.7
1015
8522
BAA99
NOMESCO Finland
Other operation on thyroid gland
45.0
7.7
9
*
L03
ICPC
Low back symptom/complaint
1.2
7.7
1731
15272
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.3
7.6
697
5620
H02AB04
ATC
methylprednisolone; systemic
1.3
7.6
729
5910
L13.0
ICD-10 Finland
Dermatitis herpetiformis
3.3
7.6
27
81
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
4.5
7.6
18
40
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.2
7.6
1588
13920
E21.0
ICD-10 Finland
Primary hyperparathyroidism
1.9
7.6
95
512
E66.9
ICD-10 Finland
Obesity, unspecified
1.6
7.6
187
1212
-34
ICPC
Blood test
1.7
7.6
135
808
C08CA01
ATC
amlodipine; oral
1.2
7.5
1763
15602
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.3
7.5
683
5506
A02BC03
ATC
lansoprazole; oral
1.2
7.5
1446
12588
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.4
7.5
313
2254
SPAT1283
SPAT
Restricted health certificate
1.2
7.5
1037
8754
H50.52
ICD-10 Finland
Exophoria
2.1
7.5
65
308
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
2.5
7.5
45
182
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
2.2
7.4
60
276
R03BA05
ATC
fluticasone; inhalant
1.2
7.4
969
8130
2440A
ICD-9 Finland
Acquired hypothyroidism, Postsurgical hypothyroidism
80.2
7.4
8
*
EB1VA, ,
NOMESCO Finland
1.2
7.4
1006
8476
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
7.3
3038
28049
L13
ICPC
Hip symptom/complaint
1.2
7.3
1053
8919
N03AX16
ATC
[U] pregabalin
1.2
7.3
1161
9933
E66.01
ICD-10 Finland
Obesity due to excess calories
1.3
7.2
529
4148
A01
ICPC
Pain general/multiple sites
1.3
7.2
523
4098
K59.1
ICD-10 Finland
Functional diarrhoea
1.4
7.2
282
2009
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
1.7
7.2
116
676
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
1.6
7.2
159
1006
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.3
7.1
684
5548
R13
ICD-10 Finland
Dysphagia
1.4
7.1
299
2156
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.2
7.1
741
6069
H01.0
ICD-10 Finland
Blepharitis
1.3
7.1
396
2990
XCW12
NOMESCO Finland
Assessment of colour vision
7.9
7.1
15
19
R55
ICD-10 Finland
Syncope and collapse
1.3
7.1
466
3605
J01DA01
ATC
[U] cefalexin
1.1
7.0
3644
34132
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.3
7.0
640
5164
H05.0
ICD-10 Finland
Acute inflammation of orbit
7.0
7.0
16
23
SPAT1281
SPAT
Other administrative function
1.4
7.0
348
2583
E66.8
ICD-10 Finland
Other obesity
1.4
7.0
299
2165
E0000UV, ,
ATC
1.2
7.0
2414
21986
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.3
6.9
678
5511
N17
ICPC
Vertigo/dizziness
1.3
6.9
638
5151
Z00.8
ICD-10 Finland
Other general examinations
1.3
6.9
395
2993
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
6.9
1535
13513
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.1
6.9
3083
28577
R74
ICPC
Upper respiratory infection acute
1.2
6.9
2123
19171
R03BB04
ATC
tiotropium bromide; inhalant
1.3
6.8
387
2928
P06
ICPC
Sleep disturbance
1.2
6.8
706
5775
SFA30
NOMESCO Finland
Three-surface restoration
1.2
6.8
2428
22142
-50
ICPC
Medication/prescr/renewal
1.6
6.8
169
1098
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.3
6.8
652
5289
TFP35
NOMESCO Finland
Electroanatomical mapping
2.1
6.8
63
307
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
5.6
6.7
18
32
S01GX01
ATC
cromoglicic acid; ophthalmic
1.2
6.7
1198
10349
AR6
HP
Catheter ablation of arrhythmia, target: atrial fibrillation
3.5
6.7
22
63
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.2
6.7
1401
12272
E50.9
ICD-10 Finland
Vitamin A deficiency, unspecified
22.5
6.7
9
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.2
6.7
697
5711
Z3229
NOMESCO Finland
Other healthcare associate professional
1.4
6.6
348
2606
R01AD12
ATC
fluticasone furoate; nasal
1.2
6.6
1911
17166
E27.2
ICD-10 Finland
Addisonian crisis
12.2
6.6
11
9
D09
ICPC
Nausea
1.4
6.6
243
1715
F13
ICPC
Eye sensation abnormal
1.6
6.6
142
895
I48.2
ICD-10 Finland
Chronic atrial fibrillation
1.6
6.5
151
968
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.2
6.5
875
7362
C01DA14
ATC
isosorbide mononitrate; oral
1.3
6.5
458
3578
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.2
6.4
740
6124
E83.50
ICD-10 Finland
Hypercalcemia
2.0
6.4
66
334
E03.3
ICD-10 Finland
Postinfectious hypothyroidism
69.9
6.4
7
*
E03.82
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
69.9
6.4
7
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.4
6.4
283
2061
Z50.5
ICD-10 Finland
Speech therapy
2.1
6.4
54
254
D64.9
ICD-10 Finland
Anaemia, unspecified
1.3
6.4
421
3259
H3603, E103,
ICD-10 Finland
2.3
6.4
43
184
K77
ICPC
Heart failure
1.9
6.4
75
398
R20.2
ICD-10 Finland
Paraesthesia of skin
1.3
6.4
375
2856
M01AH01
ATC
celecoxib; oral
1.2
6.4
898
7589
WX704
NOMESCO Finland
Intubation
1.3
6.3
406
3129
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
2.1
6.3
54
255
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
1.6
6.3
145
927
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
1.7
6.3
108
641
S94
ICPC
Ingrowing nail
1.8
6.3
82
449
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.2
6.3
975
8311
T72
ICPC
Benign neoplasm thyroid
5.2
6.3
18
35
R07.0
ICD-10 Finland
Pain in throat
1.3
6.3
396
3044
Z01.9
ICD-10 Finland
Special examination, unspecified
1.4
6.3
283
2067
OAB42
NOMESCO Finland
Guidance related to known health problem
3.5
6.3
21
61
S01XA18
ATC
ciclosporin; ophthalmic
2.3
6.3
45
198
P01AB01
ATC
metronidazole; oral, rectal
1.1
6.3
2432
22282
E8901, E050,
ICD-10 Finland
+∞
6.2
6
*
2410A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic uninodular goitre
+∞
6.2
6
*
H060, E050,
ICD-10 Finland
+∞
6.2
6
*
BA1MN
NOMESCO Finland
Thyroid gland isotope imaging with calculation
+∞
6.2
6
*
2419X
ICD-9 Finland
Non-toxic nodular goitre, Unspecified non-toxic nodular goitre
+∞
6.2
6
*
M48.0
ICD-10 Finland
Spinal stenosis
1.3
6.2
502
3987
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.5
6.2
201
1382
A97
ICPC
No disease
1.2
6.2
1038
8907
A63.0
ICD-10 Finland
Anogenital (venereal) warts
1.5
6.2
194
1326
SFA10
NOMESCO Finland
One-surface restoration
1.1
6.2
3310
30953
R01BA52
ATC
pseudoephedrine, combinations; oral
1.2
6.2
1716
15348
C07AB03
ATC
atenolol; systemic
1.5
6.2
200
1377
R03DC03
ATC
montelukast; oral
1.2
6.2
936
7965
R61.9
ICD-10 Finland
Hyperhidrosis, unspecified
2.0
6.1
65
333
Z01.2
ICD-10 Finland
Dental examination
1.1
6.1
2838
26293
R96
ICPC
Asthma
1.3
6.1
513
4098
C10AA03
ATC
pravastatin; oral
1.4
6.1
258
1866
SPAT1254
SPAT
Administration of medicine
1.2
6.1
632
5174
M54.4
ICD-10 Finland
Lumbago with sciatica
1.2
6.1
1008
8650
E07
ICD-10 Finland
Other disorders of thyroid
10.0
6.0
11
11
M79.7
ICD-10 Finland
Fibromyalgia
1.5
6.0
203
1409
Z02.7
ICD-10 Finland
Issue of medical certificate
1.3
6.0
346
2627
N01
ICPC
Headache
1.2
6.0
632
5182
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
3885
2199
40.24
307.65
8.1
1.6
4.82
4.49
pmol/l
25.42
3693
1963
2047
3473
8.02
307.65
1.4
1.2
220.39
73.23
u/ml
36.37
1120
1145
3573
778
96.39
307.65
3.5
1.1
19.52
2.05
iu/l
1.24
2400
216
6498
46822
11.23
307.65
16.4
2.8
15.67
14.31
pmol/l
307.65
6326
43331
4259
27900
2.43
258.37
7.9
6.5
1.21
1.22
mmol/l
3.22
3688
24129
1110
3999
3.12
231.40
3.2
3.6
61.17
87.47
ng/l
21.22
988
3468
6555
55260
7.32
222.81
17.9
3.9
1.72
1.83
mu/l
5.53
6374
51707
3786
24759
2.20
213.45
6.8
6.0
1.21
1.22
mmol/l
0.91
3552
22971
218
205
10.96
201.85
4.2
1.1
128.35
135.76
u/ml
0.03
89
33
162
100
16.57
192.35
1.7
1.2
15.89
13.88
pmol/l
2.62
145
82
4641
34319
2.13
172.72
10.3
9.6
3.79
4.03
e9/l
12.06
4075
29812
3034
20252
1.90
139.57
3.2
3.4
2.34
2.36
mmol/l
17.51
2795
18511
5469
44834
2.16
131.20
9.6
8.0
79.26
77.20
u/l
3.13
5267
42628
3783
28379
1.76
107.66
2.8
2.4
76.13
77.38
nmol/l
2.10
3502
26169
5312
44392
1.92
101.86
4.7
4.3
11.47
11.50
mm/h
0.06
5052
41879
3965
31607
1.62
77.03
6.2
6.5
0.19
0.19
e9/l
0.45
3515
27794
2210
15307
1.66
76.10
1.4
1.3
1.86
1.54
u/ml
0.54
621
4248
3670
28800
1.60
75.40
6.2
6.4
28.55
28.53
%
0.04
3461
27383
3900
31221
1.59
72.21
6.0
6.4
1.87
1.93
e9/l
1.75
3495
27650
3831
30600
1.58
71.12
6.0
6.3
0.04
0.04
e9/l
2.93
3345
26428
975
5431
1.93
70.37
2.1
2.0
371.87
381.39
nmol/l
0.77
901
5054
3819
30539
1.58
70.08
6.0
6.3
0.55
0.56
e9/l
0.05
3344
26384
3577
28334
1.56
67.20
6.0
6.3
56.51
57.00
%
1.75
3416
27131
6378
58904
2.49
66.39
19.0
15.6
139.73
139.70
mmol/l
0.61
6290
57770
6386
59025
2.50
66.10
19.3
15.7
3.94
3.94
mmol/l
0.09
6290
57771
4029
33250
1.52
59.17
5.1
4.6
6.58
6.50
mmol/l
1.51
3814
31198
6115
56140
1.94
55.21
16.2
13.3
84.87
84.47
ml/min/173m2
0.81
5738
51523
319
1256
2.62
53.68
1.3
1.2
—
—
—
0
0
1841
13110
1.56
52.26
1.6
1.5
2.22
2.28
g/l
1.02
1118
8249
3746
30940
1.47
51.12
3.6
3.1
97.20
99.49
ug/l
0.31
3523
29261
3292
26556
1.47
50.44
13.1
10.5
0.00
0.00
e9/l
0.05
2729
21484
1072
6808
1.68
48.31
5.0
5.5
1.07
1.04
mmol/l
2.84
1001
6316
6527
61935
2.60
46.05
15.2
11.3
24.52
24.76
u/l
0.59
6428
60382
6275
58761
1.96
43.76
16.5
14.1
19.98
22.42
mg/l
8.02
5250
47682
5902
54299
1.69
43.53
6.6
5.5
39.15
38.22
mmol/mol
11.64
5556
51287
3142
25682
1.42
41.69
4.7
4.8
36.14
36.16
g/l
0.08
2929
24153
3645
30582
1.42
41.67
6.2
6.3
10.62
10.61
umol/l
0.03
3461
29134
1979
14896
1.46
41.02
2.4
2.3
2.68
2.73
mg/l
0.36
1728
12994
1929
14539
1.46
39.37
3.5
2.9
1179.59
1110.78
ng/l
0.34
1643
12413
715
4312
1.74
38.39
3.9
3.6
1.22
1.23
mmol/l
3.57
623
3738
1305
9140
1.53
38.09
3.2
3.4
0.81
0.82
mmol/l
1.43
1236
8631
6518
62223
2.36
38.03
21.5
17.5
71.46
70.95
umol/l
0.74
6458
61538
6001
55971
1.65
35.57
5.2
4.6
5.85
5.77
mmol/l
4.67
5603
52115
2981
24768
1.36
32.87
2.2
2.0
97.55
97.94
pmol/l
0.16
1601
12747
2941
24445
1.36
32.07
14.8
12.0
1.21
1.18
inr
2.47
2514
20125
1290
9375
1.46
30.62
2.6
2.5
13.50
13.45
umol/l
0.10
1188
8765
1207
8672
1.48
30.34
2.6
2.4
2.42
2.39
g/l
1.09
1105
8036
2486
20357
1.35
28.92
3.9
3.3
73.86
67.79
ng/l
0.06
1518
12440
230
1046
2.24
28.14
2.0
1.9
4.92
5.22
mmol/24h
0.73
202
939
1502
11423
1.40
27.38
2.8
2.8
2.44
2.45
mmol/l
3.55
1321
10283
2264
18424
1.34
26.93
2.6
2.6
66.98
64.26
u/l
0.09
2085
17128
5426
50316
1.40
25.32
23.5
17.1
13.53
13.52
%
0.19
5370
49662
1254
9374
1.41
24.94
1.4
1.4
562.10
525.46
titre
0.29
305
2015
2079
16862
1.34
24.80
2.2
2.1
187.33
184.34
u/l
0.03
1971
15992
1083
7935
1.43
24.00
2.7
2.5
22.02
22.67
%
0.97
993
7388
154
637
2.45
23.46
1.9
1.4
49.19
23.92
ng/l
1.93
154
637
1735
13814
1.34
23.12
2.1
1.7
0.97
1.07
mg/l
1.14
1326
10675
1519
11868
1.36
22.87
1.4
1.3
7.14
10.36
u/ml
1.58
584
4862
1621
12834
1.35
22.29
1.4
1.3
28.21
30.19
iu/ml
0.25
482
4006
3256
28485
1.28
20.86
2.7
2.7
—
—
estimate
—
0
0
4581
41828
1.30
20.79
3.4
3.1
41.64
41.64
u/l
0.00
4369
39659
1353
10537
1.36
20.48
4.1
3.5
213.56
362.65
ng/l
1.65
961
7377
6097
58260
1.48
19.52
5.2
4.7
4.71
4.80
mmol/l
10.59
5743
55092
6603
64388
2.14
19.49
29.7
21.3
90.57
90.87
fl
6.77
6568
63842
6602
64375
2.14
19.49
29.9
21.4
262.23
261.40
e9/l
0.53
6527
63229
6604
64408
2.14
19.38
30.0
21.5
134.72
133.70
g/l
9.38
6568
63868
6603
64396
2.13
19.35
30.3
21.7
40.40
40.58
%
0.42
6562
63816
6603
64397
2.13
19.34
29.8
21.3
4.51
4.45
e12/l
18.06
6503
63077
6603
64405
2.13
19.20
29.9
21.4
6.52
6.64
e9/l
4.32
6506
63072
2029
16865
1.29
19.08
4.5
4.0
6.96
8.20
mg/mmol
0.80
1212
9962
1096
8355
1.37
18.85
1.8
1.7
1095.84
1182.99
nmol/l
2.70
865
6421
6147
58920
1.48
18.45
5.9
5.2
2.78
2.82
mmol/l
3.95
5769
55461
6063
57973
1.45
18.32
5.2
4.6
1.51
1.54
mmol/l
8.75
5686
54540
2178
18375
1.27
17.93
3.6
3.3
7.15
7.20
mmol/l
0.22
1845
15680
5789
54978
1.37
17.62
4.3
3.9
1.24
1.24
mmol/l
0.08
5387
51319
1990
16636
1.28
17.56
3.8
3.3
36.14
42.99
mg/l
1.01
1226
9980
2394
20537
1.26
16.85
3.3
3.2
29.09
31.84
u/l
2.25
2279
19442
498
3347
1.53
16.81
1.2
1.1
1.88
1.82
u/ml
—
6
30
1413
11373
1.31
16.56
1.7
1.7
46348041.72
36583034.57
pmol/l
0.24
1191
9674
1768
14682
1.28
16.21
2.2
2.2
—
—
—
0
0
2860
25109
1.24
16.15
2.0
1.9
1.31
1.34
mmol/l
0.97
2377
21480
1867
15672
1.26
15.53
1.7
1.6
20.39
20.75
nmol/l
0.51
1626
13387
4298
39548
1.24
15.20
5.1
4.5
1489.33
2580.37
e6/l
0.65
73
483
328
2061
1.62
14.84
1.3
1.3
42.80
45.26
u/ml
0.05
20
123
589
4196
1.44
14.84
2.3
2.6
65.91
66.73
g/l
1.88
545
3872
668
4879
1.41
14.64
3.7
3.8
5.91
5.82
kpa
1.44
647
4764
649
4744
1.41
14.15
3.7
3.8
1.96
1.92
mmol/l
0.09
559
4178
87
352
2.49
14.06
1.8
1.5
103.72
94.78
ng/l
0.16
87
352
460
3165
1.49
13.86
1.2
1.1
103.80
192.44
titre
0.99
20
88
83
332
2.52
13.75
1.2
1.1
13.43
20.43
u/l
1.87
76
298
83
332
2.52
13.75
1.2
1.2
68.95
77.05
u/l
0.85
77
298
304
1912
1.62
13.72
1.3
1.3
25.17
6.67
u/ml
1.04
38
289
1497
12423
1.26
13.38
2.9
2.6
6.68
7.07
e6/l
0.47
1370
11228
302
1913
1.61
13.24
1.3
1.3
11.23
5.83
u/ml
0.24
23
175
2111
18230
1.23
13.13
3.6
3.2
47.00
68.87
e6/l
0.46
1623
13545
2058
17759
1.23
12.82
3.7
3.2
0.49
0.19
estimate
0.35
650
5211
705
5320
1.36
12.64
3.3
3.2
—
—
—
0
0
1095
8801
1.29
12.60
1.9
1.9
—
—
—
0
0
3524
32087
1.21
12.57
4.0
3.8
0.00
0.00
estimate
2.81
783
6481
3560
32454
1.20
12.51
4.0
3.8
1.90
5.04
estimate
0.82
792
6642
127
634
2.02
12.43
1.2
1.2
80.00
57.07
u/l
2.52
112
556
2460
21686
1.21
12.23
4.3
3.7
80.50
98.65
e6/l
0.80
1725
14556
528
3836
1.41
11.90
3.4
2.8
206.74
164.94
ng/l
0.61
475
3498
3568
32693
1.19
11.35
4.1
3.8
0.07
0.37
estimate
0.68
770
6381
1737
14890
1.22
11.25
4.2
3.8
91.55
94.03
%
3.99
1693
14559
1709
14630
1.23
11.21
2.5
2.4
321.55
319.76
umol/l
0.30
1507
13083
573
4285
1.37
10.85
2.3
2.6
72.29
70.14
e9/l
0.57
416
3055
1823
15762
1.21
10.74
3.5
3.1
0.33
0.41
e6/l
1.46
1337
11212
2257
19928
1.20
10.63
3.6
3.2
—
2.48
—
0
16
294
1951
1.53
10.58
1.6
1.9
0.23
0.23
g/l
0.01
276
1861
248
1584
1.59
10.57
1.2
1.3
49.05
44.25
u/ml
0.18
28
170
439
3158
1.42
10.47
3.2
3.4
5.21
5.16
kpa
0.50
419
3019
246
1579
1.58
10.27
1.2
1.3
0.99
2.99
u/ml
1.41
16
106
623
4760
1.34
10.25
1.4
1.3
28.55
29.29
iu/l
0.22
536
4147
1072
8816
1.26
10.05
2.1
2.5
122.46
113.63
ug/g
0.28
838
7043
297
2007
1.50
9.83
1.6
1.9
1.21
1.19
g/l
0.74
277
1922
601
4627
1.33
9.38
2.6
2.8
10.28
10.45
g/l
0.49
551
4309
267
1783
1.52
9.37
1.1
1.1
5.57
6.50
eliau/ml
0.18
43
244
561
4292
1.33
9.15
7.9
7.2
9.50
8.89
mmol/l
1.26
535
4133
368
2632
1.42
9.09
2.9
3.3
2.08
1.85
mmol/l
0.45
263
1951
303
2093
1.47
9.02
2.0
2.0
—
—
—
0
0
387
2798
1.41
9.00
1.9
1.9
4.85
7.16
iu/ml
1.18
66
675
861
7001
1.26
8.83
2.7
2.6
6.55
7.55
umol/l
0.97
741
6035
71
325
2.20
8.83
2.4
1.8
18.39
20.18
nmol/l
0.93
66
311
75
355
2.13
8.59
1.1
1.1
2.77
10.31
nmol/l
0.72
12
65
145
860
1.70
8.36
4.1
3.3
0.76
0.81
nmol/l
1.23
125
689
358
2607
1.39
8.01
2.2
2.1
40.63
39.94
u/l
0.24
325
2357
36
125
2.89
7.99
1.2
1.1
7.93
10.54
pmol/l
0.31
12
44
728
5877
1.27
7.91
4.6
4.3
233.94
242.12
u/l
1.01
683
5592
526
4074
1.32
7.88
3.2
3.1
4.53
4.55
kpa
0.11
508
3970
158
976
1.63
7.83
1.3
1.2
331.11
286.10
titre
0.11
18
82
103
565
1.84
7.79
1.2
1.2
—
—
—
0
0
111
628
1.78
7.60
1.2
1.2
—
—
—
0
0
256
1774
1.46
7.56
2.2
2.3
0.30
0.84
g/l
2.84
223
1541
277
1952
1.44
7.48
2.0
2.3
2.90
2.89
g/l
0.12
258
1789
271
1921
1.43
7.11
1.9
1.8
—
—
—
0
0
96
532
1.82
7.07
1.2
1.2
—
—
—
0
0
202
1357
1.50
6.99
2.2
2.3
0.00
0.00
g/l
-0.00
194
1280
321
2351
1.38
6.98
1.6
1.6
11.66
17.00
iu/ml
—
5
69
97
542
1.80
6.96
1.2
1.2
—
—
—
0
0
285
2047
1.41
6.95
2.2
2.3
4.26
4.26
g/l
0.00
266
1883
97
543
1.80
6.92
1.2
1.2
—
—
—
0
0
285
2049
1.41
6.91
2.2
2.3
3.74
3.68
g/l
0.25
265
1885
214
1459
1.48
6.89
2.1
2.3
0.00
0.00
g/l
0.50
194
1283
221
1517
1.47
6.88
2.1
2.3
0.00
0.02
g/l
0.79
203
1371
2657
24377
1.15
6.88
4.0
3.7
1.62
0.46
estimate
0.52
643
5298
285
2052
1.41
6.86
2.2
2.3
7.45
7.40
g/l
0.19
265
1888
72
367
1.97
6.84
1.5
1.5
6.19
6.24
u/l
0.01
57
303
145
913
1.60
6.71
1.1
1.2
42.80
8.37
u/ml
—
5
37
575
4609
1.27
6.63
7.7
7.6
1.30
1.28
mmol/l
0.16
563
4526
232
1628
1.44
6.46
2.2
2.2
11.62
11.57
mg/l
0.03
221
1531
26
85
3.07
6.45
1.6
1.6
—
—
—
0
0
396
3034
1.32
6.44
3.4
3.2
131.07
128.57
g/l
1.53
383
2950
462
3630
1.29
6.26
1.9
1.9
1.16
1.36
g/l
2.92
432
3370
565
4556
1.26
6.21
2.4
2.4
16.19
21.31
au/ml
1.38
62
565
92
525
1.76
6.20
1.2
1.2
—
—
—
0
0
2012
18206
1.15
6.19
3.1
2.9
0.04
0.06
0.21
28
361
245
1756
1.41
6.09
2.3
2.3
9.78
10.19
g/l
1.05
225
1579
220
1547
1.44
6.09
3.2
3.0
1.71
2.00
index
0.42
104
794
453
3568
1.29
6.03
1.1
1.1
—
—
—
0
0
481
3827
1.28
5.91
2.2
2.2
8.27
6.40
ug/l
0.65
408
3340
767
6428
1.22
5.91
1.8
1.8
—
—
—
0
0
1905
17225
1.15
5.86
4.2
4.0
0.00
0.00
estimate
2.58
753
6130
75
411
1.83
5.80
1.3
1.4
11.88
11.73
umol/l
0.05
70
395
156
1035
1.52
5.80
2.1
2.2
5.48
6.09
umol/l
0.28
107
775
250
1819
1.39
5.72
1.3
1.2
112.14
133.42
titre
0.28
28
193
229
1646
1.40
5.63
3.0
3.6
24.88
24.92
mmol/l
0.07
208
1509
330
2516
1.33
5.60
1.7
1.5
277.25
291.20
mu/l
0.45
286
2273
103
627
1.65
5.53
3.1
3.2
3.36
14.35
nmol/l
0.66
98
603
233
1686
1.40
5.52
1.4
1.3
11.65
12.21
u/l
0.23
191
1376
552
4502
1.25
5.51
1.5
1.3
153.29
199.84
u/ml
1.13
521
4196
650
5399
1.23
5.47
2.2
2.2
0.21
0.21
g/l
0.14
603
5081
122
779
1.58
5.41
1.3
1.6
407.83
338.73
mu/l
0.67
98
626
1029
8937
1.18
5.35
3.3
2.8
3.89
3.71
e6/l
0.17
522
4051
182
1272
1.44
5.26
2.0
2.2
131.82
128.18
g/l
1.38
143
981
142
945
1.51
5.24
1.1
1.1
2.75
3.12
eliau/ml
0.18
70
471
517
4211
1.25
5.23
1.3
1.3
58.61
50.86
au/ml
0.23
26
268
117
746
1.58
5.23
1.2
1.3
0.18
0.18
nmol/l
0.04
94
580
691
5810
1.21
5.16
2.7
2.4
42.04
47.08
u/l
0.22
581
4903
4318
41296
1.13
5.12
3.4
3.3
—
—
—
0
0
133
879
1.52
5.08
1.3
1.3
0.28
0.26
nmol/l
—
10
63
104
651
1.61
5.04
1.2
1.2
115.40
50.59
u/ml
—
5
37
698
5890
1.21
5.02
7.6
7.6
5.11
5.10
kpa
0.09
672
5665
131
867
1.52
4.98
1.1
1.1
192.76
13006.40
iu/ml
0.55
27
186
85
507
1.69
4.97
1.4
1.2
0.78
1.78
u/ml
0.98
48
286
697
5888
1.20
4.95
7.6
7.6
12.62
12.93
kpa
0.81
671
5664
350
2742
1.29
4.91
1.3
1.3
0.92
1.20
u/ml
0.23
29
231
381
3021
1.28
4.86
9.9
9.6
24.38
24.33
mmol/l
0.12
375
2971
37
168
2.21
4.86
1.3
1.7
0.53
0.39
ug/l
0.89
24
126
113
731
1.56
4.78
1.3
1.4
—
—
—
0
0
498
4085
1.24
4.75
1.7
1.7
—
—
—
0
0
613
5137
1.21
4.74
8.0
8.1
95.52
95.88
%
0.68
586
4960
149
1024
1.47
4.74
1.8
1.6
0.82
0.70
g/l
0.81
109
799
56
300
1.87
4.72
1.8
1.6
4.85
4.56
nmol/l
0.03
48
239
688
5834
1.20
4.70
7.6
7.6
0.97
0.97
mmol/l
0.01
562
4826
236
1762
1.35
4.67
1.5
1.4
284.52
282.63
ug/g
0.05
150
971
114
744
1.54
4.65
1.3
1.4
—
—
—
0
0
112
730
1.54
4.60
1.3
1.4
—
—
—
0
0
291
2248
1.31
4.56
2.0
1.7
1.46
1.53
g/l
0.64
249
1955
138
945
1.47
4.49
2.4
2.4
98.81
76.32
ug/min
0.27
89
545
712
6083
1.19
4.48
1.8
1.8
—
—
—
0
0
525
4367
1.22
4.39
2.6
2.3
0.38
0.41
e6/l
0.13
498
4125
87
542
1.61
4.35
1.2
1.2
111.37
116.04
pmol/l
0.46
87
542
412
3347
1.25
4.31
2.3
2.2
6190.87
5473.32
u/l
0.18
175
1349
304
2383
1.29
4.29
2.4
2.1
11.06
11.57
nmol/l
0.40
276
2149
127
866
1.48
4.25
1.2
1.3
71.42
60.79
u/ml
—
8
63
49
261
1.88
4.24
1.1
1.3
149.08
146.78
mmol/24h
0.09
49
261
106
699
1.52
4.17
1.3
1.4
—
—
—
0
0
106
699
1.52
4.17
1.3
1.4
—
—
—
0
0
362
2913
1.26
4.13
9.1
9.6
16.10
15.93
%
0.52
348
2800
66
389
1.70
4.10
1.4
1.5
26.30
21.49
umol/l
0.57
61
357
267
2075
1.30
4.04
3.4
3.1
25.61
25.40
mmol/l
0.46
256
2009
62
365
1.71
3.89
1.2
1.2
17.53
23.05
u/l
0.56
51
305
104
697
1.50
3.82
1.3
1.4
—
—
—
0
0
24
103
2.33
3.65
1.6
1.2
66.04
79.71
mu/l
0.13
19
80
16
56
2.86
3.62
8.7
12.0
4.92
4.89
mmol/l
0.02
16
56
12
342
0.35
3.58
20.8
14.2
746.25
824.56
nmol/l
0.26
12
329
762
6672
1.16
3.57
5.1
4.5
33.35
32.87
%
0.59
537
4495
62
375
1.66
3.55
1.2
1.2
73.76
85.50
u/l
0.52
51
321
60
360
1.67
3.55
1.7
1.2
4.70
5.09
umol/l
0.41
55
320
233
1813
1.30
3.54
3.1
3.2
1106.86
396.35
mg/l
0.54
118
711
568
4887
1.18
3.34
8.5
8.4
121.15
120.33
g/l
0.43
550
4767
229
1795
1.29
3.31
1.1
1.2
3.98
4.10
0.06
29
287
136
988
1.38
3.31
2.9
3.6
2.44
2.48
mmol/l
0.08
97
667
14
353
0.40
3.23
20.2
19.1
1097.00
4124.58
nmol/l
0.58
14
342
386
3219
1.21
3.22
1.6
1.7
—
—
—
0
0
121
869
1.40
3.16
1.6
1.7
—
—
—
0
0
228
1805
1.27
3.08
2.0
2.1
243.04
596.29
ug/l
2.00
209
1688
84
567
1.49
3.06
1.5
1.7
—
—
—
0
0
906
8122
1.13
3.03
2.6
2.1
29.77
29.33
s
1.32
873
7886
58
361
1.61
3.03
1.1
1.1
—
—
—
0
0
21
93
2.26
3.02
1.8
2.0
6.86
7.10
mmol/l
0.11
13
57
1093
9913
1.12
3.02
3.2
2.7
1.10
1.31
e6/l
0.75
584
5038
37
204
1.82
2.98
1.4
2.2
376.40
18678.93
u/ml
—
5
27
57
357
1.60
2.91
1.6
1.6
6.12
5.20
u/l
0.63
46
309
91
632
1.45
2.89
2.2
2.0
24.74
26.06
mg/l
0.08
34
231
123
901
1.37
2.89
1.4
1.5
21.28
13.08
u/ml
—
5
17
110
791
1.40
2.89
1.3
1.3
310.27
353.91
pmol/l
0.46
91
681
144
1083
1.34
2.86
1.7
1.7
—
—
—
0
0
113
820
1.38
2.82
3.1
3.7
1.07
1.44
%
1.18
100
750
175
1364
1.29
2.71
1.7
1.3
22.96
27.98
e6/l
0.18
134
988
77
525
1.47
2.71
1.5
1.7
—
—
—
0
0
180
1409
1.29
2.70
1.8
1.6
10651.41
11048.24
e6/l
0.05
127
981
171
1333
1.29
2.66
1.5
1.6
—
—
—
0
0
165
1281
1.30
2.64
1.3
1.3
29.02
29.84
u/l
0.11
133
1055
196
1559
1.26
2.60
1.3
1.3
—
—
—
0
0
0
69
0.00
2.59
0.0
1.8
—
—
—
0
0
332
2799
1.20
2.54
3.3
3.2
1.02
1.02
ratio
0.65
296
2493
63
419
1.51
2.53
1.1
1.1
1.06
1.05
ratio
0.13
49
341
756
6785
1.13
2.51
5.6
5.2
2.17
2.63
ug/l
1.12
665
6146
220
1782
1.24
2.51
1.2
1.3
—
—
—
0
0
176
1392
1.27
2.46
1.8
1.4
522.95
3957.11
e6/l
0.67
143
1080
84
595
1.42
2.46
1.1
1.3
—
—
titre
—
0
0
39
233
1.68
2.44
1.6
1.3
—
—
—
0
0
39
233
1.68
2.44
1.6
1.3
—
—
—
0
0
204
1649
1.24
2.38
3.4
3.1
39.39
52.79
mg/l
1.41
166
1388
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
188
1508
1.25
2.36
4.2
3.2
0.37
0.37
iu/ml
0.05
103
812
10
33
3.03
2.35
1.0
1.2
—
—
—
0
0
34
198
1.72
2.34
14.2
3.1
75.72
1094.50
mg/l
0.49
25
141
228
1873
1.22
2.30
2.2
1.9
2.12
1.86
ug/l
0.14
203
1668
43
269
1.60
2.28
1.6
1.8
—
—
—
0
0
43
269
1.60
2.28
1.6
1.8
—
—
—
0
0
43
269
1.60
2.28
1.6
1.8
—
—
—
0
0
475
4163
1.15
2.28
1.5
1.6
938.99
1029.77
mu/l
1.22
382
3469
203
1650
1.24
2.27
3.4
3.1
33.01
46.32
mg/l
1.04
165
1391
57
381
1.50
2.27
1.2
1.3
48.12
2761.70
pmol/l
—
5
42
182
1463
1.25
2.25
3.3
3.0
1.24
4.49
ratio
3.06
98
808
43
270
1.60
2.25
1.6
1.8
—
—
—
0
0
140
1091
1.29
2.24
1.6
1.7
—
—
—
0
0
53
350
1.52
2.23
1.3
1.3
13.00
9.86
mm/h
0.71
53
350
0
61
0.00
2.23
0.0
1.1
—
—
—
0
0
173
1386
1.25
2.21
1.5
1.6
—
—
—
0
0
23
122
1.89
2.15
1.1
1.1
—
—
—
0
0
146
1151
1.27
2.14
1.4
1.4
149.68
152.09
au/ml
0.09
43
315
49
322
1.53
2.13
1.1
1.1
—
—
—
0
0
129
1003
1.29
2.12
2.4
2.1
0.88
0.84
nmol/l
0.23
101
878
22
116
1.90
2.10
1.1
1.1
355.69
316.86
pmol/l
0.11
16
86
15
69
2.18
2.04
1.1
1.1
—
—
—
0
0
84
618
1.36
2.03
1.7
1.6
—
—
—
0
0
11
44
2.50
2.01
1.1
1.1
29.45
8.91
u/l
0.39
11
44
49
328
1.50
1.97
1.5
1.3
—
—
—
0
0
373
3254
1.15
1.95
1.4
1.5
—
—
—
0
0
48
322
1.49
1.92
1.5
1.3
—
—
—
0
0
602
5427
1.12
1.90
4.3
4.3
23.60
21.39
%
2.14
263
2526
66
476
1.39
1.83
3.0
2.5
21.33
27.13
mg/l
0.81
49
340
72
528
1.37
1.81
3.4
3.8
55.81
55.90
%
0.01
63
467
78
580
1.35
1.80
1.4
1.4
278.37
276.52
mosm/kgh2o
0.26
57
433
53
369
1.44
1.79
1.6
1.5
35.40
22.14
u/ml
—
5
69
147
1190
1.24
1.78
6.3
5.8
291.60
831.89
iu/ml
1.08
20
154
46
312
1.48
1.77
3.9
3.4
0.87
0.86
index
0.05
46
306
90
686
1.32
1.76
6.7
6.1
12.39
11.91
mg/l
0.51
83
640
6
18
3.34
1.74
1.0
1.2
3.00
3.00
%
—
6
18
320
2787
1.16
1.74
1.4
1.4
—
—
—
0
0
296
2565
1.16
1.72
1.6
1.6
12.11
14.99
u/ml
0.49
65
664
62
448
1.39
1.71
1.1
1.2
—
—
—
0
0
287
2484
1.16
1.70
1.7
1.7
—
—
—
0
0
502
4514
1.12
1.68
1.6
1.5
—
—
—
0
0
62
450
1.38
1.68
1.1
1.2
—
—
—
0
0
59
425
1.39
1.67
1.6
1.6
—
—
—
0
0
59
425
1.39
1.67
1.6
1.6
—
—
—
0
0
59
425
1.39
1.67
1.6
1.6
—
—
—
0
0
157
1294
1.22
1.63
1.2
1.2
46.65
45.32
u/ml
—
6
20
40
269
1.49
1.63
1.6
2.3
147.16
145.36
umol/l
0.01
19
146
63
462
1.37
1.61
1.2
1.2
195.00
215.00
titre
0.07
12
78
83
635
1.31
1.61
1.6
1.6
54.85
55.84
%
0.08
59
387
37
246
1.51
1.59
1.5
1.5
—
—
—
0
0
37
246
1.51
1.59
1.5
1.5
—
—
—
0
0
126
1019
1.24
1.58
2.3
2.9
31.90
32.79
umol/l
0.14
109
922
97
764
1.27
1.53
1.3
1.5
—
—
—
0
0
43
298
1.45
1.52
1.1
1.3
135.21
132.73
nmol/l
0.11
43
298
103
819
1.26
1.50
1.1
1.1
1.50
1.49
g/l
0.10
98
753
342
3030
1.14
1.49
5.6
6.7
24.71
24.58
mmol/l
0.26
322
2889
455
4102
1.12
1.49
3.0
3.1
0.73
0.74
ug/l
0.09
290
2575
47
333
1.41
1.49
1.3
1.1
—
—
—
0
0
12
58
2.07
1.49
1.1
1.1
2.64
1.68
iu/ml
—
7
31
76
582
1.31
1.49
2.0
1.5
—
—
—
0
0
43
300
1.44
1.48
2.3
1.5
—
—
—
0
0
31
202
1.54
1.48
1.7
2.0
—
—
—
0
0
31
202
1.54
1.48
1.7
2.0
—
—
—
0
0
76
583
1.31
1.47
1.8
1.7
89.53
90.06
%
0.25
76
572
177
1495
1.19
1.46
2.1
1.6
—
—
—
0
0
144
1194
1.21
1.44
1.3
1.4
2.32
3.55
ug/l
2.58
125
1058
125
1022
1.23
1.44
1.3
1.4
—
—
—
0
0
259
2259
1.15
1.43
4.7
4.7
1.74
1.62
%
0.81
244
2128
31
204
1.52
1.42
1.7
2.0
—
—
—
0
0
31
204
1.52
1.42
1.1
1.2
—
—
—
0
0
124
1015
1.23
1.42
1.4
1.4
—
—
—
0
0
72
552
1.31
1.41
1.3
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
42
295
1.43
1.41
1.2
1.1
—
—
—
0
0
80
623
1.29
1.40
1.1
1.0
—
—
—
0
0
171
1447
1.19
1.39
1.6
1.4
—
—
—
0
0
51
372
1.37
1.39
3.1
2.9
959.30
863.16
u/ml
0.21
46
372
14
74
1.89
1.38
1.6
1.7
5.39
608070.71
nmol/l
1.08
14
62
76
591
1.29
1.35
12.1
4.0
7.51
7.39
mmol/l
0.09
64
497
9
42
2.14
1.33
1.1
1.3
—
—
—
0
0
26
168
1.55
1.31
1.1
1.1
—
—
—
0
0
15
83
1.81
1.31
1.4
1.3
1.45
1.70
mmol/l
—
8
52
160
1358
1.18
1.28
1.7
1.4
0.46
0.43
nmol/l
0.18
122
1040
184
1582
1.17
1.26
1.5
1.3
488.39
501.00
mg/l
0.17
173
1510
70
547
1.28
1.23
1.4
1.5
1544.56
3638.58
e6/l
0.70
52
384
145
1227
1.19
1.22
1.2
1.3
255.47
274.44
u/ml
0.44
94
767
43
313
1.38
1.21
1.2
1.1
—
—
—
0
0
19
116
1.64
1.21
1.1
1.0
80.66
74.93
ug/l
0.15
12
97
545
5907
0.92
1.20
1.7
1.6
3.53
3.49
mmol/l
0.24
377
3972
28
189
1.48
1.18
1.7
1.4
—
—
—
0
0
62
480
1.29
1.18
1.4
1.3
2.08
2.02
mmol/l
0.23
57
448
34
239
1.42
1.17
1.2
1.2
0.30
0.30
g/l
0.29
28
194
63
489
1.29
1.17
1.2
1.4
1.59
1.46
nmol/l
0.32
53
443
32
223
1.44
1.16
1.2
1.2
114.81
110.24
%
0.42
26
204
33
232
1.42
1.14
1.5
1.3
108.12
174.99
nmol/24h
0.42
33
232
0
36
0.00
1.14
0.0
1.2
—
21.35
—
0
26
7
30
2.33
1.12
1.0
1.1
—
—
—
0
0
123
1038
1.19
1.09
1.4
1.6
—
—
—
0
0
58
451
1.29
1.08
1.4
1.4
6.84
6.38
mmol/l
0.63
53
429
19
120
1.58
1.08
1.1
1.2
—
—
—
0
0
7
32
2.19
1.08
1.3
1.0
—
—
—
0
0
117
985
1.19
1.07
1.1
1.1
1.19
2.80
1.82
15
179
207
1826
1.14
1.05
3.2
2.5
3.46
3.64
g/l
1.02
200
1737
185
1620
1.15
1.04
2.8
3.2
1.53
1.43
mg/l
0.93
174
1489
233
2076
1.13
1.01
5.0
5.0
0.85
0.88
%
0.61
220
1954
83
681
1.22
1.00
1.1
1.1
—
4.20
—
0
6
245
2192
1.12
1.00
1.3
1.3
—
—
—
0
0
26
180
1.45
1.00
2.7
2.6
0.62
0.61
mmol/l
0.15
26
180
352
3212
1.10
1.00
10.9
9.9
0.61
0.65
%
1.25
352
3193
98
819
1.20
0.99
1.2
1.2
—
—
—
0
0
61
485
1.26
0.98
1.1
1.0
—
—
—
0
0
5
23
2.17
0.98
1.2
1.4
0.78
0.84
umol/l
—
5
14
0
29
0.00
0.97
0.0
1.1
—
0.03
—
0
29
10
54
1.85
0.96
1.7
2.4
40.99
59.44
pmol/l
—
10
48
190
1680
1.13
0.95
2.6
2.7
—
—
—
0
0
57
452
1.26
0.94
1.9
2.2
—
—
—
0
0
59
470
1.26
0.94
1.6
1.5
31.85
32.68
%
0.06
40
280
362
3320
1.10
0.94
10.7
9.7
94.17
94.21
%
0.04
362
3308
20
133
1.51
0.94
1.1
1.1
—
—
—
0
0
135
1167
1.16
0.93
4.4
3.3
21.11
25.77
mg/l
1.12
88
815
64
516
1.24
0.93
1.8
1.7
—
—
—
0
0
619
5807
1.07
0.92
2.1
2.1
0.01
0.02
estimate
0.46
112
1221
46
357
1.29
0.91
1.9
1.9
—
—
—
0
0
74
608
1.22
0.91
1.4
1.5
30.56
32.96
g/l
0.86
67
557
38
287
1.33
0.91
1.3
1.6
—
—
—
0
0
23
159
1.45
0.91
1.1
1.1
—
—
—
0
0
166
1463
1.14
0.89
1.4
1.5
68.91
60.10
ug/l
1.31
166
1463
364
3350
1.09
0.89
1.3
1.4
—
—
—
0
0
141
1229
1.15
0.89
1.4
1.4
—
—
—
0
0
119
1024
1.17
0.89
1.2
1.2
—
—
—
0
0
119
1024
1.17
0.89
1.2
1.2
—
—
—
0
0
80
665
1.21
0.88
1.6
1.6
—
—
—
0
0
22
152
1.45
0.87
1.1
1.1
—
—
—
0
0
217
1949
1.12
0.86
2.7
2.1
94.79
95.46
%
0.17
207
1875
42
325
1.29
0.86
1.7
2.3
596.68
639.93
ml
0.39
34
229
68
558
1.22
0.86
3.2
3.1
11.00
10.69
mmol/l
0.34
68
549
52
414
1.26
0.85
1.3
1.2
0.71
0.63
ratio
0.27
30
246
17
112
1.52
0.84
1.9
1.3
1.19
1.17
mmol/l
0.38
17
112
66
541
1.22
0.84
1.2
1.1
41.32
39.67
mg/l
0.10
50
460
16
104
1.54
0.84
1.1
1.1
11.32
6.32
u/ml
0.62
16
104
188
1678
1.12
0.84
1.2
1.2
—
—
—
0
0
35
265
1.32
0.84
1.1
1.2
—
—
—
0
0
69
569
1.21
0.83
1.4
1.5
—
—
—
0
0
266
2421
1.10
0.83
1.3
1.6
0.25
0.31
mg/l
1.01
108
1092
66
542
1.22
0.83
3.8
3.1
15.57
13.45
index
0.47
46
306
218
1964
1.11
0.83
1.6
1.6
—
—
—
0
0
25
343
0.73
0.83
1.0
1.0
672.33
742.48
ng/l
0.36
18
246
109
938
1.16
0.83
2.6
2.7
75.80
877.87
u/ml
—
5
47
38
292
1.30
0.82
1.1
1.0
90.16
92.65
%
0.26
25
231
158
1397
1.13
0.82
1.4
1.2
3.84
3.64
mmol/l
1.35
153
1329
1531
14794
1.05
0.82
3.6
3.7
0.08
0.60
0.74
12
134
189
1691
1.12
0.82
1.2
1.2
—
—
—
0
0
228
2514
0.90
0.80
1.1
1.1
0.60
0.60
ratio
0.00
31
319
17
114
1.49
0.79
1.1
1.2
—
—
—
0
0
745
7839
0.94
0.79
1.9
1.9
3.46
3.34
ratio
1.23
572
5851
122
1065
1.15
0.78
1.3
1.2
3.75
3.42
u/ml
0.06
61
370
48
386
1.25
0.75
1.2
1.0
1.35
1.13
u/l
0.49
22
151
14
91
1.54
0.75
2.4
1.5
1.20
1.21
mmol/l
0.25
14
86
17
244
0.70
0.75
2.6
3.3
7.37
8.58
mg/l
0.28
12
192
124
1089
1.14
0.74
1.8
1.7
—
—
—
0
0
35
272
1.29
0.72
1.3
1.6
—
—
—
0
0
26
345
0.75
0.72
1.0
1.0
34.33
43.55
ng/l
0.57
18
250
112
979
1.15
0.72
1.1
1.1
113.57
118.55
%
0.87
97
890
10
60
1.67
0.72
1.0
1.0
—
—
—
0
0
13
84
1.55
0.71
1.2
1.1
—
—
—
0
0
228
2081
1.10
0.71
3.1
3.5
114.14
1186.65
u/ml
1.45
190
1778
40
318
1.26
0.70
1.4
1.3
9.82
11.50
u/l
0.65
33
293
276
2989
0.92
0.69
1.5
1.5
—
—
—
0
0
5
27
1.85
0.68
1.8
1.7
0.94
6.00
nmol/l
—
5
27
103
902
1.14
0.66
1.4
1.4
6.78
6.99
mmol/l
0.38
92
804
5
28
1.79
0.66
1.6
1.5
552.12
456.83
nmol/l
—
5
28
129
1147
1.13
0.66
1.6
1.5
—
—
—
0
0
26
339
0.77
0.65
1.0
1.0
256.84
335.69
ng/l
1.03
19
248
261
2411
1.09
0.64
1.4
1.5
60.40
60.72
ug/l
0.04
210
1998
57
477
1.20
0.64
1.3
1.4
13159.08
55847.39
e6/l
2.17
37
262
70
597
1.17
0.64
1.1
1.1
—
—
—
0
0
28
216
1.30
0.63
3.2
4.2
—
—
—
0
0
246
2273
1.09
0.61
1.4
1.5
0.92
0.95
ratio
0.84
148
1385
246
2273
1.09
0.61
1.4
1.5
1.19
1.22
ratio
0.14
150
1390
31
244
1.27
0.61
1.0
1.1
1982.00
622.76
ng/l
—
5
65
36
445
0.81
0.60
1.1
1.5
—
—
—
0
0
245
2266
1.08
0.60
1.4
1.5
1.10
1.15
ratio
0.45
147
1377
98
863
1.14
0.60
1.2
1.1
0.94
1.19
—
9
40
62
527
1.18
0.60
1.1
1.1
250.22
235.23
mg/l
0.25
50
469
111
986
1.13
0.59
1.3
1.4
—
—
—
0
0
243
2248
1.08
0.59
1.4
1.5
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
9519.83
—
0
6
37
299
1.24
0.59
1.9
1.6
1.27
1.42
nmol/l
0.35
30
224
16
114
1.40
0.58
1.1
1.1
0.49
0.70
umol/24h
—
7
53
22
166
1.33
0.58
4.0
3.7
65.33
108.25
ng/l
—
10
71
624
5966
1.05
0.56
3.5
4.2
40.05
24.71
ug/l
0.23
489
4705
14
98
1.43
0.56
2.6
1.6
1.17
1.19
mmol/l
0.64
14
93
8
55
1.46
0.56
1.1
1.2
1.32
1.67
umol/24h
—
8
55
92
812
1.13
0.56
1.2
1.2
31.46
29.63
u/l
0.04
84
696
14
195
0.72
0.56
1.0
1.1
—
—
—
0
0
6
37
1.62
0.55
1.3
1.1
8.73
7.91
mmol/l
—
6
37
12
82
1.46
0.54
1.2
1.3
—
—
—
0
0
116
1042
1.12
0.53
5.7
6.6
11.80
11.21
mmol/l
0.80
105
926
815
7855
1.04
0.53
2.0
2.1
—
—
—
0
0
116
1043
1.11
0.53
5.7
6.6
104.70
105.20
mmol/l
0.52
105
928
10
66
1.52
0.52
1.4
1.4
—
0.86
—
0
7
1460
14232
1.03
0.52
4.0
3.9
1.02
1.12
kg/l
0.50
1018
9307
6
99
0.61
0.51
4.3
1.3
—
—
—
0
0
49
416
1.18
0.50
1.8
1.6
—
—
—
0
0
57
659
0.86
0.49
5.9
5.2
367.97
363.45
umol/l
0.09
47
579
11
76
1.45
0.48
2.7
2.0
—
—
—
0
0
11
77
1.43
0.45
1.1
1.2
—
—
—
0
0
11
77
1.43
0.45
1.1
1.1
—
—
—
0
0
36
428
0.84
0.45
2.7
1.9
1.94
1.81
u/field
0.08
18
232
7
50
1.40
0.45
5.0
2.5
—
—
—
0
0
10
69
1.45
0.44
7.1
6.5
12.20
10.55
%
—
10
69
747
7223
1.04
0.44
1.6
1.7
1.36
1.39
%
0.90
659
6427
36
302
1.19
0.44
1.3
1.6
—
—
—
0
0
9
127
0.71
0.43
3.2
2.0
13.58
16.13
umol/l
—
9
127
8
56
1.43
0.42
1.1
1.1
—
—
—
0
0
22
176
1.25
0.41
1.6
1.3
16.17
16.92
umol/l
0.43
22
151
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
279.63
—
0
16
49
426
1.15
0.40
2.6
2.6
490.57
541.53
e6/l
0.38
40
344
25
204
1.23
0.40
1.5
1.5
0.54
0.50
e9/l
0.37
25
204
8
60
1.33
0.40
1.5
1.2
—
—
—
0
0
120
1305
0.92
0.40
3.2
4.1
3.84
3.82
mmol/l
0.20
120
1294
24
196
1.23
0.39
1.0
1.1
—
—
—
0
0
135
1249
1.08
0.38
1.1
1.1
13.86
15.84
au/ml
0.13
32
318
32
377
0.85
0.38
1.1
1.1
1453.25
1520.21
miu/ml
0.13
32
377
9
68
1.32
0.37
1.1
1.1
—
—
—
0
0
9
70
1.29
0.36
1.1
1.1
—
—
—
0
0
38
439
0.86
0.36
1.1
1.2
—
—
—
0
0
252
2654
0.95
0.35
1.4
1.3
207.13
232.87
miu/ml
0.57
129
1305
43
375
1.15
0.35
1.3
1.6
—
—
—
0
0
22
181
1.22
0.34
2.1
2.9
31.17
28.48
umol/l
0.43
15
138
13
167
0.78
0.34
1.6
1.2
111.31
107.00
%
0.16
13
158
482
4652
1.04
0.34
3.3
3.6
45.66
54.14
u/ml
0.38
464
4510
44
386
1.14
0.34
1.4
1.3
—
—
—
0
0
33
283
1.17
0.34
3.1
2.8
16.89
207.61
ug/l
0.98
33
268
5127
50991
1.02
0.34
24.1
17.8
331.60
331.65
g/l
0.16
5110
50731
18
145
1.24
0.33
2.0
4.1
5.16
4.99
kpa
0.28
18
145
30
256
1.17
0.33
1.0
1.1
—
—
—
0
0
6
47
1.28
0.32
1.0
1.0
—
—
—
0
0
18
146
1.23
0.32
2.0
4.1
9.72
10.09
kpa
0.38
18
146
32
276
1.16
0.31
2.0
2.2
9.89
7.67
mmol/l
1.04
32
276
194
1837
1.06
0.31
3.6
2.3
175.14
185.90
%
1.19
187
1750
7
53
1.32
0.30
1.0
1.2
—
—
—
0
0
48
428
1.12
0.30
1.2
1.6
1.10
1.12
promille
0.02
40
331
7
54
1.30
0.30
1.0
1.1
—
—
—
0
0
54
487
1.11
0.29
1.4
1.5
27.03
36.59
nmol/l
1.58
47
449
890
8711
1.02
0.28
2.2
2.1
—
—
—
0
0
28
323
0.87
0.28
1.5
1.5
—
1597096.18
—
0
17
8
62
1.29
0.28
3.0
2.7
0.88
0.76
u/field
—
8
62
8
63
1.27
0.27
1.6
2.6
15.93
14.89
ml/dl
—
8
57
49
441
1.11
0.27
2.6
2.8
201.90
228.68
e6/l
0.58
42
374
24
205
1.17
0.27
1.5
1.8
40.09
40.66
g/l
0.21
24
205
36
318
1.13
0.27
2.2
2.7
41.04
43.91
%
0.43
18
184
107
1143
0.94
0.27
1.3
1.2
—
—
—
0
0
25
215
1.16
0.26
1.8
2.1
192.20
117.35
ug/min
—
5
40
136
1284
1.06
0.26
1.1
1.1
1.54
1.41
u/ml
0.09
73
623
11
86
1.28
0.26
1.5
1.6
—
—
—
0
0
41
367
1.12
0.25
1.8
1.4
73.51
73.50
umol/l
0.00
41
367
9
72
1.25
0.25
1.9
1.9
—
—
—
0
0
61
560
1.09
0.24
1.0
1.1
8.59
8.10
iu/ml
0.07
13
146
51
464
1.10
0.24
1.1
1.0
0.53
1.14
u/ml
0.61
12
109
16
133
1.20
0.24
1.1
1.2
45.19
65.49
ug/l
2.20
16
133
144
1367
1.05
0.24
1.0
1.1
3.44
4.92
u/ml
0.94
82
720
12
97
1.24
0.22
6.2
7.3
6.47
5.53
kpa
0.47
12
97
34
379
0.90
0.22
2.0
2.7
—
—
—
0
0
10
79
1.27
0.22
1.2
1.3
5.80
5.75
mmol/l
—
10
79
53
487
1.09
0.22
4.2
4.1
—
—
—
0
0
120
1138
1.06
0.21
3.3
3.4
74.11
584.11
u/ml
1.45
110
1031
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
28.73
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.01
—
0
10
257
2483
1.04
0.21
2.0
1.7
3.58
4.44
mg/l
1.20
211
1827
138
1315
1.05
0.21
1.1
1.1
0.46
1.04
u/ml
2.22
60
551
5
43
1.16
0.21
1.0
1.1
0.92
1.12
mom
—
5
43
44
481
0.91
0.21
1.2
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
6.81
—
0
14
6
50
1.20
0.19
1.0
1.0
—
—
—
0
0
26
291
0.89
0.19
3.2
1.7
0.95
2.54
u/field
2.40
19
204
10
81
1.23
0.18
1.0
1.0
—
—
—
0
0
55
511
1.08
0.18
1.1
1.1
—
—
—
0
0
84
793
1.06
0.18
1.1
1.2
—
—
—
0
0
94
990
0.95
0.18
1.0
1.1
0.25
0.26
u/ml
0.04
34
311
301
2931
1.03
0.17
2.1
2.1
0.06
0.27
estimate
0.38
90
974
222
2152
1.03
0.17
1.6
1.5
0.37
0.63
iu/ml
0.22
32
378
7
63
1.11
0.17
1.1
1.1
—
—
—
0
0
46
427
1.08
0.16
1.7
1.9
3.41
3.51
mg/l
0.09
46
411
12
141
0.85
0.16
1.0
1.1
—
—
—
0
0
16
139
1.15
0.16
1.1
1.3
—
—
—
0
0
105
1098
0.96
0.16
1.0
1.1
1.51
4.19
u/ml
2.99
50
486
12
140
0.86
0.15
1.1
1.1
—
—
—
0
0
9
81
1.11
0.15
1.8
1.8
—
—
—
0
0
45
482
0.93
0.15
3.0
2.7
—
—
—
0
0
25
227
1.10
0.14
1.2
1.1
57.94
59.33
u/ml
0.04
25
219
24
219
1.10
0.12
2.1
2.3
—
—
—
0
0
16
179
0.89
0.12
1.7
1.7
9.22
8.78
ug/l
0.11
16
179
472
4649
1.02
0.12
2.9
2.5
68.54
70.76
ml/min/173m2
0.58
218
1921
620
6121
1.01
0.12
6.2
5.9
—
—
—
0
0
16
143
1.12
0.11
1.1
1.1
—
—
—
0
0
54
513
1.05
0.11
1.1
1.1
19.01
16.44
u/ml
0.26
25
231
5
46
1.09
0.09
1.0
1.1
—
—
—
0
0
5
47
1.06
0.09
1.4
1.4
58.80
44.87
umol/l
—
5
47
16
145
1.10
0.09
1.1
1.0
—
—
—
0
0
160
1565
1.02
0.09
1.1
1.1
2.00
1.95
u/ml
0.02
83
815
106
1031
1.03
0.08
1.3
1.2
3.05
3.87
u/ml
0.66
60
441
105
1022
1.03
0.08
1.1
1.1
—
—
—
0
0
5
65
0.77
0.08
1.0
1.1
—
—
—
0
0
18
195
0.92
0.08
1.5
2.2
943.55
882.32
e6/l
0.05
11
133
8
76
1.05
0.07
1.3
1.4
—
—
—
0
0
30
284
1.06
0.07
1.2
1.2
1483.33
973.33
titre
—
6
60
16
147
1.09
0.07
1.1
1.1
—
—
—
0
0
67
649
1.03
0.07
1.0
1.0
—
—
—
0
0
583
5781
1.01
0.07
2.0
2.0
—
—
—
0
0
11
122
0.90
0.07
1.3
1.1
—
—
—
0
0
8
95
0.84
0.06
1.0
1.0
—
—
—
0
0
39
375
1.04
0.05
1.9
1.6
—
—
—
0
0
38
395
0.96
0.05
1.1
1.6
12.39
8.41
ug/l
0.25
31
353
20
189
1.06
0.04
3.5
2.5
143.70
152.13
nmol/l
0.14
20
165
14
130
1.08
0.04
1.6
2.4
—
—
—
0
0
21
199
1.06
0.04
3.1
3.8
1.64
1.20
%
0.31
21
199
467
4701
0.99
0.04
2.0
1.9
—
—
—
0
0
31
322
0.96
0.04
1.9
1.7
1.46
1.59
u/ml
—
9
86
15
160
0.94
0.04
1.1
1.1
27.17
34.62
iu/ml
0.31
15
160
10
109
0.92
0.04
1.4
2.3
17.10
4.81
ug/l
—
10
109
12
129
0.93
0.03
1.5
1.1
—
—
—
0
0
27
280
0.96
0.03
1.1
1.2
—
—
—
0
0
21
201
1.04
0.03
1.0
1.2
—
—
—
0
0
12
112
1.07
0.03
1.3
1.2
16.48
397.17
ug/l
—
6
57
19
182
1.04
0.02
1.2
1.1
—
—
—
0
0
22
227
0.97
0.01
1.2
1.1
88.56
94.20
%
—
9
87
13
127
1.02
0.00
1.1
1.1
—
—
—
0
0
16
164
0.98
0.00
1.4
2.0
4071.67
20548.95
e6/l
—
6
83
51
507
1.01
0.00
1.4
1.4
23007.47
78518.90
e6/l
1.43
32
349
22
218
1.01
0.00
1.1
1.1
6.06
9.91
u/ml
0.66
17
151
22
221
1.00
0.00
1.2
1.2
89.20
94.47
%
—
10
89
115
1151
1.00
0.00
1.1
1.1
2.89
3.41
u/ml
0.19
52
549
5
50
1.00
-0.00
1.8
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
19
190
1.00
-0.00
1.3
1.4
210.78
197.91
pmol/l
0.08
19
190
0
8
0.00
-0.00
0.0
3.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
52.27
—
0
6
8
79
1.01
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
18.00
—
0
6
6
68
0.88
-0.00
1.2
1.2
133.33
89.88
titre
—
6
68
Mortality – FinRegistry
↥Association
Association between endpoint E4_THYTOXGOITDIF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_THYTOXGOITDIF | 1.072 [0.97, 1.19] | 0.195 |
| Birth year | 0.998 [0.99, 1.01] | 0.668 |
During the follow-up period (1.1.1998 — 31.12.2019), 2220 out of 23978 females with E4_THYTOXGOITDIF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_THYTOXGOITDIF | 1.256 [1.11, 1.42] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 772 out of 5286 males with E4_THYTOXGOITDIF died.
Mortality risk
Mortality risk for people of age
years, who have E4_THYTOXGOITDIF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.133% | 0.248% |
| 5 | 0.717% | 1.366% |
| 10 | 1.728% | 3.515% |
| 15 | 3.315% | 6.757% |
| 20 | 5.89% | 11.323% |
Relationships between endpoints
↥Index endpoint: E4_THYTOXGOITDIF – Thyrotoxicosis with diffuse goitre
GWS hits: 34
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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