Autoimmune hyperthyroidism

AUTOIMMUNE_HYPERTHYROIDISM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • E4_THYTOXGOITDIF
7162

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E05.9
  • Cause of death: ICD-10 E05.9

2 out of 7 registries used, show all original rules.

2979

4. Check minimum number of events

None

2979

5. Include endpoints

None

2979

6. Filter based on genotype QC (FinnGen only)

2700

Control definitions (FinnGen only)

Control exclude
AUTOIMMUNE
Control conditions
not E4_THYTOXGOITDIF

Extra metadata

First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14824 11965 2766
Only index persons 14358 11690 2668
Unadjusted period prevalence (%)
Whole population 0.29 0.34 0.08
Only index persons 0.37 0.43 0.10
Median age at first event (years)
Whole population 50.67 50.39 52.43
Only index persons 50.46 50.13 51.92

-FinnGen-

Key figures

All Female Male
Number of individuals 2700 2246 454
Unadjusted period prevalence (%) 0.70 0.80 0.21
Median age at first event (years) 51.23 50.15 56.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2808
Matched controls
28080
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
28.3
307.7
281
110
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
985.8
307.7
2479
213
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
82.5
307.7
457
66
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
307.7
750
*
104
Kela drug reimbursment
Thyroid insufficiency
38.2
307.7
844
312
H03AA01
ATC
levothyroxine sodium; systemic
89.3
307.7
2138
969
T85
ICPC
Hyperthyroidism/thyrotoxicosis
67.5
307.7
195
31
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
26.2
307.7
229
95
H03BB01
ATC
carbimazole; oral
1068.3
307.7
2543
250
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
128.1
307.7
443
41
C07AA05
ATC
propranolol; systemic
5.3
307.7
1288
3880
BAA60
NOMESCO Finland
Total thyroidectomy
34.4
307.7
789
315
E03
ICD-10 Finland
Other hypothyroidism
30.2
307.7
353
133
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
18.0
307.7
271
166
T86
ICPC
Hypothyroidism/myxoedema
30.4
307.7
343
128
E03.89
ICD-10 Finland
Other specified hypothyroidism
28.1
307.7
309
123
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
35.8
307.7
776
296
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
338650.7
307.7
2787
11
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
38.4
307.7
587
192
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
29.7
302.0
202
73
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
80.9
287.4
153
20
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
88.6
241.5
127
15
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.4
219.5
1316
5757
H062, E050,
ICD-10 Finland
+∞
209.0
198
*
E05.89
ICD-10 Finland
Other thyrotoxicosis
87.3
191.6
101
12
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
184.4
175
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.6
179.8
375
755
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
28.1
178.4
121
45
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
45.4
177.6
105
24
C07AB07
ATC
bisoprolol; oral
3.0
172.0
1563
8354
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
73.9
159.3
86
12
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.8
149.7
1550
8664
L04AX03
ATC
methotrexate; systemic
6.5
147.2
255
428
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
51.4
139.0
80
16
H04AA01
ATC
glucagon; nasal, parenteral
65.2
127.1
70
11
K90.0
ICD-10 Finland
Coeliac disease
15.8
120.9
105
69
H50.2
ICD-10 Finland
Vertical strabismus
17.2
118.0
98
59
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
13.1
114.9
111
88
A10AA01, ,
ATC
59.5
114.3
64
11
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
138.0
112.0
119
9
E06.3
ICD-10 Finland
Autoimmune thyroiditis
50.4
110.7
64
13
T89
ICPC
Diabetes insulin dependent
11.4
107.1
113
103
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
40.9
105.5
64
16
H53.2
ICD-10 Finland
Diplopia
6.2
104.4
185
316
H02AB06
ATC
prednisolone; systemic
2.3
97.6
1427
8764
CA1AD
NOMESCO Finland
Orbita CT
51.9
97.4
56
11
A10AB01
ATC
insulin (human); parenteral
17.8
95.7
78
45
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
30.2
93.8
62
21
E10
ICD-10 Finland
Type 1 diabetes mellitus
47.2
86.9
51
11
H05.2
ICD-10 Finland
Exophthalmic conditions
156.7
86.6
91
6
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.3
84.3
363
1226
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
425.0
83.4
83
*
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
7.0
76.6
119
177
XCK00
NOMESCO Finland
Perimetry
3.9
76.4
241
663
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
45.7
76.0
45
10
A10AB04
ATC
insulin lispro; parenteral
11.1
74.9
80
74
H03BA02
ATC
propylthiouracil; oral
256.8
73.7
75
*
A10AA02, ,
ATC
14.0
72.5
67
49
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.2
69.8
193
482
H02AB07
ATC
prednisone; oral
2.7
69.8
420
1700
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
68.7
549
2546
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
13.3
68.3
65
50
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
65.9
63
*
ZX120
NOMESCO Finland
Intravenous
3.1
64.0
297
1042
A11CC03
ATC
alfacalcidol; systemic
6.4
63.9
107
172
L01BA01
ATC
methotrexate; systemic
13.7
63.1
59
44
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
21.7
63.1
47
22
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.3
61.4
166
407
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
21.2
61.2
46
22
A10AB05
ATC
insulin aspart; parenteral
4.0
58.6
174
457
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
57.1
446
2034
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
150.6
56.1
59
*
CEC00
NOMESCO Finland
Recession of extraocular muscle
17.3
55.8
46
27
A07EC02
ATC
mesalazine; oral, rectal
6.8
55.7
88
133
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
52.4
1212
8191
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
+∞
52.2
50
*
P01BA02
ATC
hydroxychloroquine; oral
3.9
49.8
152
407
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
+∞
48.1
46
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
5.3
46.4
95
185
E05.5
ICD-10 Finland
Thyroid crisis or storm
238.9
46.1
47
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
45.3
618
3488
A10AE05
ATC
insulin detemir; parenteral
4.4
44.9
115
270
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
5.4
44.9
90
172
106
Kela drug reimbursment
Hypoparathyroidism
12.9
43.5
42
33
L04AA13
ATC
[U] leflunomide
11.7
43.0
44
38
ZXA10
NOMESCO Finland
Bilateral
2.0
42.2
526
2868
XCK10
NOMESCO Finland
Photography of fundus of eye
2.8
41.3
227
868
K51.5
ICD-10 Finland
Left sided colitis
68.2
41.1
47
7
H50.6
ICD-10 Finland
Mechanical strabismus
111.7
40.8
44
*
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.1
40.2
171
567
C07AB02
ATC
metoprolol; systemic
2.0
39.5
492
2677
A07EC01
ATC
sulfasalazine; oral, rectal
3.7
39.3
130
368
WF099
NOMESCO Finland
Other radiotherapy
10.1
39.0
44
44
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
87.4
38.9
43
5
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
38.5
973
6593
A10AC01
ATC
insulin (human); parenteral
3.3
38.4
152
483
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.1
38.3
431
2257
L40.0
ICD-10 Finland
Psoriasis vulgaris
6.8
36.5
57
85
H50.0
ICD-10 Finland
Convergent concomitant strabismus
8.1
35.9
48
60
L04AA06
ATC
mycophenolic acid; systemic
6.3
35.6
60
97
A02BC02
ATC
pantoprazole; systemic
1.7
35.6
1891
15434
107
Kela drug reimbursment
Pernicious anaemia
+∞
35.5
34
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.3
34.8
134
418
G35
ICD-10 Finland
Multiple sclerosis
182.3
34.8
36
*
A10AE06
ATC
insulin degludec; parenteral
4.9
34.2
75
155
L04AX01
ATC
azathioprine; systemic
6.4
34.2
57
91
CAC44
NOMESCO Finland
Combined decompression of orbit
341.2
34.0
34
*
L88
ICPC
Rheumatoid/seropositive arthritis
5.3
33.8
69
134
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
33.8
717
4595
C01BD01
ATC
amiodarone; systemic
4.4
33.1
83
192
A10AE04
ATC
insulin glargine; parenteral
2.7
32.7
190
747
H50.8
ICD-10 Finland
Other specified strabismus
37.8
32.5
41
11
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
9.6
32.4
38
40
E83.51
ICD-10 Finland
Hypocalcemia
8.0
32.4
44
56
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
7.5
32.3
46
62
TFP20
NOMESCO Finland
Cardiodefibrillation
2.8
32.0
172
649
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
+∞
31.3
30
*
H02AB09
ATC
hydrocortisone; systemic
4.7
30.6
72
158
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
+∞
30.3
29
*
CAC20
NOMESCO Finland
Lateral decompression of orbit
+∞
30.3
29
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
29.7
695
4551
Z3231
NOMESCO Finland
Registered nurse
1.7
29.5
691
4524
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
29.5
608
3843
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.0
29.5
130
440
109
Kela drug reimbursment
Multiple sclerosis
+∞
29.2
28
*
H3600, E103,
ICD-10 Finland
+∞
29.2
28
*
R00.2
ICD-10 Finland
Palpitations
2.1
29.2
291
1449
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
6.7
28.9
46
70
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
81.0
28.8
32
*
B03BA03
ATC
hydroxocobalamin; parenteral
3.3
28.6
110
343
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
+∞
28.2
27
*
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
+∞
28.2
27
*
C03CA01
ATC
furosemide; systemic
1.7
27.9
592
3767
R06.0
ICD-10 Finland
Dyspnoea
1.7
27.6
698
4652
WX402
NOMESCO Finland
General anaesthesia
1.7
27.5
661
4348
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
53.9
27.2
32
6
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
53.9
27.2
32
6
R53
ICD-10 Finland
Malaise and fatigue
1.6
27.1
724
4890
2AB04, ,
NOMESCO Finland
75.9
26.8
30
*
207
Kela drug reimbursment
Chronic arrhythmias
2.0
26.6
328
1762
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
+∞
26.1
25
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.5
25.5
162
664
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
+∞
25.0
24
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
24.8
992
7337
N05CF01
ATC
zopiclone; oral
1.6
24.4
808
5724
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
22.1
24.3
35
16
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
+∞
24.0
23
*
A07EA06
ATC
budesonide; oral, local oral
4.5
23.8
58
131
K51.8
ICD-10 Finland
Other ulcerative colitis
126.1
23.6
25
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.7
23.2
132
513
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.1
23.2
231
1148
H3603, E103,
ICD-10 Finland
+∞
22.9
22
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
5.4
22.1
43
80
H3601, E103,
ICD-10 Finland
+∞
21.9
21
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.3
21.9
179
822
A04
ICPC
Weakness/tiredness general
1.7
21.6
430
2672
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
5.5
21.5
41
75
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
21.5
324
1856
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
50.4
21.1
25
5
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
+∞
20.9
20
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.3
20.4
157
702
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
20.4
580
3943
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
20.4
839
6189
A07EA02
ATC
hydrocortisone; rectal
6.8
20.0
31
46
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
2.1
19.9
198
983
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
+∞
19.8
19
*
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
19.7
291
1654
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
40.4
19.5
24
6
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
46.3
19.2
23
5
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
55.4
18.9
22
*
N02BE01
ATC
paracetamol; systemic, rectal
1.7
18.7
2462
22660
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
18.7
243
1326
I50.9
ICD-10 Finland
Heart failure, unspecified
1.9
18.3
236
1284
A02BC05
ATC
esomeprazole; systemic
1.4
18.3
1048
8208
CS494
NOMESCO Finland
Other visual field testing
3.1
18.0
73
236
CEW99
NOMESCO Finland
Other operation on extraocular muscle
33.1
18.0
23
7
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
33.1
18.0
23
7
C07AA07
ATC
sotalol; systemic
3.0
17.7
80
275
2420A
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic diffuse goitre
+∞
17.7
17
*
K50.8
ICD-10 Finland
Other Crohn disease
+∞
17.7
17
*
G73.0*E05.9
ICD-10 Finland
Myasthenic syndromes in thyrotoxicosis [hyperthyroidism]
+∞
17.7
17
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
17.6
474
3168
H57.1
ICD-10 Finland
Ocular pain
2.4
17.6
123
528
K04
ICPC
Palpitations/awareness of heart
2.1
17.6
164
794
B01AA03
ATC
warfarin; systemic
1.7
17.6
328
1996
K50.0
ICD-10 Finland
Crohn disease of small intestine
181.1
17.5
18
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
181.1
17.5
18
*
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.7
17.4
354
2205
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
17.0
17.4
27
16
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
17.0
317
1927
K50.9
ICD-10 Finland
Crohn disease, unspecified
50.3
17.0
20
*
B81
ICPC
Anaemia vit B12/folate deficiency
3.2
16.9
67
214
ZXE00
NOMESCO Finland
One hour or less
1.4
16.8
996
7815
N02AX02
ATC
tramadol; systemic, rectal
1.4
16.7
1014
7991
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
5.1
16.7
35
70
1XC02, ,
NOMESCO Finland
7.0
16.5
25
36
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
16.5
979
7680
177
Kela drug reimbursment
Insulin glargine 300 U / ml
5.0
16.4
35
71
J01DB01
ATC
cefalexin; oral
1.5
16.3
2233
20253
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
16.2
382
2468
M01CB01
ATC
sodium aurothiomalate; parenteral
30.2
16.1
21
7
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
16.0
1970
17467
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
3.5
15.8
53
152
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
15.7
456
3095
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.6
15.6
37
82
K50.1
ICD-10 Finland
Crohn disease of large intestine
+∞
15.6
15
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.6
15.6
356
2281
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
160.9
15.5
16
*
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
160.9
15.5
16
*
XF404
NOMESCO Finland
Ambulatory ECG
1.9
15.5
191
1023
XCH00
NOMESCO Finland
Eye pressure measurement
2.3
15.5
117
520
A12AA04
ATC
calcium carbonate; oral
4.6
15.4
36
79
H02AB04
ATC
methylprednisolone; systemic
1.7
15.4
342
2177
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
15.3
665
4910
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
16.1
15.2
24
15
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
15.0
994
7913
CKC12
NOMESCO Finland
Photocoagulation of retina
2.5
14.8
89
356
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
14.7
478
3324
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
14.7
1105
8978
WZC30
NOMESCO Finland
Teaching
1.6
14.6
379
2505
H20.1
ICD-10 Finland
Chronic iridocyclitis
150.8
14.5
15
*
E05.3
ICD-10 Finland
Thyrotoxicosis from ectopic thyroid tissue
150.8
14.5
15
*
N06AX21
ATC
duloxetine; oral
1.6
14.3
316
2007
F29
ICPC
Eye symptom/complaint other
1.7
14.2
291
1814
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
14.1
169
896
H36.00
ICD-10 Finland
Diabetic background retinopathy
6.7
14.0
22
33
B01AF02
ATC
apixaban; oral
1.7
14.0
267
1631
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
3.6
13.9
46
131
K29.4
ICD-10 Finland
Chronic atrophic gastritis
3.8
13.9
41
108
L04AB04
ATC
adalimumab; parenteral
5.6
13.8
26
47
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
23.9
13.8
19
8
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
13.7
362
2400
E06.9
ICD-10 Finland
Thyroiditis, unspecified
10.5
13.7
26
25
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
13.7
174
941
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
13.7
698
5293
SPAT1262
SPAT
Handing over of treatment supplies
1.6
13.7
324
2093
UJF32
NOMESCO Finland
Coloscopy
1.5
13.7
536
3869
M54.5
ICD-10 Finland
Low back pain
1.4
13.7
994
8006
K80
ICPC
Cardiac arrhythmia NOS
1.8
13.6
224
1313
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
+∞
13.5
13
*
164
Kela drug reimbursment
Fingolimod
+∞
13.5
13
*
L03AX13
ATC
glatiramer acetate; parenteral
+∞
13.5
13
*
CA1BD
NOMESCO Finland
Extensive orbita CT
34.2
13.5
17
5
L01BB02
ATC
mercaptopurine; oral
25.9
13.4
18
7
Z2221
NOMESCO Finland
Medical doctor
1.4
13.2
697
5311
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.4
13.2
87
364
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
13.2
281
1767
L13.0
ICD-10 Finland
Dermatitis herpetiformis
40.3
13.1
16
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
13.1
485
3459
A11CC02
ATC
dihydrotachysterol; oral
15.1
13.1
21
14
E06.1
ICD-10 Finland
Subacute thyroiditis
4.5
13.1
31
69
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
13.0
337
2226
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
50.2
12.8
15
*
TFP34
NOMESCO Finland
Electrophysiological investigation
2.4
12.8
84
351
L28
ICPC
Limited function/disability (L)
1.5
12.8
407
2811
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
11.6
12.8
23
20
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.8
12.8
186
1051
Z71.8
ICD-10 Finland
Other specified counselling
1.4
12.7
918
7366
R50.9
ICD-10 Finland
Fever, unspecified
1.6
12.7
337
2237
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
70.2
12.6
14
*
R02
ICPC
Shortness of breath/dyspnoea
1.6
12.6
316
2070
N86
ICPC
Multiple sclerosis
32.2
12.6
16
5
L04AA27
ATC
[U] fingolimod
+∞
12.5
12
*
353
Kela drug reimbursment
Cladribine and fingolimod
+∞
12.5
12
*
E50.0
ICD-10 Finland
Vitamin A deficiency with conjunctival xerosis
+∞
12.5
12
*
M14.5*E05.9
ICD-10 Finland
Arthropathy in thyrotoxicosis [hyperthyroidism]
130.6
12.4
13
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.7
12.4
255
1588
H01.0
ICD-10 Finland
Blepharitis
1.8
12.4
200
1165
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.0
12.4
144
756
C01BC04
ATC
flecainide; systemic
2.4
12.2
83
353
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
12.1
197
1151
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
26.8
12.0
16
6
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
18.1
12.0
18
10
C03DA01
ATC
spironolactone; oral
1.7
12.0
240
1485
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
12.0
194
1132
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
11.9
268
1708
N03AX16
ATC
[U] pregabalin
1.4
11.9
519
3814
WX892
NOMESCO Finland
Monitored bed care
1.9
11.9
150
810
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
4.7
11.9
27
58
L04AB01
ATC
etanercept; parenteral
5.9
11.8
21
36
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
4.9
11.7
25
51
E89.1
ICD-10 Finland
Postprocedural hypoinsulinaemia
30.1
11.6
15
5
D07AD01
ATC
clobetasol; topical
1.5
11.6
378
2622
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
11.6
303
2002
L40.5
ICD-10 Finland
Arthropathic psoriasis
19.0
11.6
17
9
R51.80
ICD-10 Finland
Headache
1.5
11.6
428
3047
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
23.0
11.6
16
7
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
11.5
211
1276
A10AD01
ATC
insulin (human); parenteral
5.7
11.5
21
37
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
120.5
11.4
12
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
3.3
11.4
41
124
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
11.3
764
6041
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
11.3
368
2551
E0000UV, ,
ATC
1.3
11.3
1026
8482
J01FF01
ATC
clindamycin; systemic
1.4
11.3
617
4714
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.7
11.3
193
1145
M25.5
ICD-10 Finland
Pain in joint
1.3
11.1
876
7090
K78
ICPC
Atrial fibrillation/flutter
1.9
11.1
137
735
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.3
11.1
81
356
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
2.8
11.0
53
190
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
11.0
558
4207
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
3.5
11.0
37
107
D01
ICPC
Abdominal pain/cramps general
1.5
11.0
335
2291
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
10.9
1010
8360
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.4
10.9
709
5568
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
10.9
1460
12717
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
43.5
10.9
13
*
E06.4
ICD-10 Finland
Drug-induced thyroiditis
43.5
10.9
13
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
10.8
1074
8981
K51
ICD-10 Finland
Ulcerative colitis
28.1
10.7
14
5
RD210, ,
NOMESCO Finland
3.3
10.7
40
124
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
10.7
694
5450
N05BA04
ATC
oxazepam; oral
1.4
10.6
653
5081
A02BC01
ATC
omeprazole; systemic
1.4
10.6
622
4803
SPAT1263
SPAT
Sampling
1.3
10.6
991
8209
C01AA05
ATC
digoxin; systemic
2.0
10.6
121
633
XF402
NOMESCO Finland
ECG with work load test
1.7
10.5
200
1220
A60
ICPC
General and Unspecified, Result test/procedure
2.0
10.5
109
551
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
10.5
286
1907
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
110.4
10.4
11
*
L04AA24
ATC
abatacept; parenteral
110.4
10.4
11
*
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
+∞
10.4
10
*
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
+∞
10.4
10
*
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
+∞
10.4
10
*
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
10.4
10
*
W84
ICPC
Pregnancy high risk
2.1
10.4
97
471
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.2
10.4
81
366
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
10.4
706
5578
N06AX11
ATC
mirtazapine; oral
1.3
10.4
849
6897
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
10.4
462
3403
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
4.2
10.3
27
65
R63.4
ICD-10 Finland
Abnormal weight loss
2.1
10.3
92
439
I47.1
ICD-10 Finland
Supraventricular tachycardia
2.0
10.3
106
534
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
10.3
97
473
A99
ICPC
Disease/condition unspecnature/site
1.6
10.3
249
1615
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
10.3
272
1802
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
10.2
886
7251
A10AD04
ATC
insulin lispro; parenteral
23.4
10.2
14
6
H05.0
ICD-10 Finland
Acute inflammation of orbit
23.4
10.2
14
6
Z01.7
ICD-10 Finland
Laboratory examination
1.4
10.2
431
3144
AA1AD
NOMESCO Finland
CT of head and brain
1.4
10.2
600
4634
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.9
10.1
121
643
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
10.0
440
3229
L17
ICPC
Foot/toe symptom/complaint
1.3
10.0
753
6034
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
2.8
10.0
48
172
F13
ICPC
Eye sensation abnormal
2.3
10.0
76
340
TNG10
NOMESCO Finland
Puncture of knee
4.8
10.0
22
46
R60.9
ICD-10 Finland
Oedema, unspecified
1.9
9.9
131
719
A01
ICPC
Pain general/multiple sites
1.6
9.9
248
1623
A29
ICPC
General symptom/complaint other
1.5
9.9
304
2082
I47.2
ICD-10 Finland
Ventricular tachycardia
3.0
9.8
42
141
M03BX02
ATC
tizanidine; oral
1.3
9.8
1664
14863
CE2W4
NOMESCO Finland
Eye movement mapping
10.6
9.8
18
17
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
9.7
173
1037
R03AC02
ATC
salbutamol; inhalant
1.3
9.7
1434
12571
N07BA03
ATC
varenicline; oral
1.9
9.7
119
638
SPAT1097
SPAT
Recording of ECG
1.5
9.7
287
1949
R05
ICPC
Cough
1.4
9.7
639
5019
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
55.2
9.6
11
*
C10AX09
ATC
ezetimibe; oral
1.5
9.6
324
2260
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
15.1
9.5
15
10
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
2.3
9.4
66
285
B01AB05
ATC
enoxaparin; parenteral
1.3
9.4
719
5767
G70.0
ICD-10 Finland
Myasthenia gravis
+∞
9.4
9
*
L03AB07
ATC
interferon beta-1a; parenteral
+∞
9.4
9
*
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
9.4
9
*
L04AA31
ATC
[U] teriflunomide
+∞
9.4
9
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.2
9.3
77
357
3AC01, ,
NOMESCO Finland
4.5
9.3
22
49
R42
ICD-10 Finland
Dizziness and giddiness
1.4
9.3
531
4075
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
8.7
9.3
19
22
M05BA04
ATC
alendronic acid; oral
1.7
9.3
171
1036
R52.9
ICD-10 Finland
Pain, unspecified
1.5
9.2
251
1673
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
3.2
9.2
36
115
WX002
NOMESCO Finland
Sedation and analgesia
1.4
9.2
405
2973
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.6
9.2
192
1202
Z3226
NOMESCO Finland
Physiotherapist
1.4
9.2
395
2887
R21
ICPC
Throat symptom/complaint
1.4
9.1
582
4541
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.5
9.1
309
2159
S01XA18
ATC
ciclosporin; ophthalmic
4.4
9.1
22
50
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
9.0
1951
17876
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
2.7
9.0
46
171
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
9.0
454
3412
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
8.9
317
2234
TFP35
NOMESCO Finland
Electroanatomical mapping
3.0
8.9
38
128
D05AX02
ATC
calcipotriol; topical
2.7
8.9
47
178
C08CA01
ATC
amlodipine; oral
1.3
8.9
773
6309
OAB50, ,
SPAT
1.7
8.8
150
889
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.5
8.8
52
208
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
9.5
8.8
17
18
E20.8
ICD-10 Finland
Other hypoparathyroidism
50.1
8.7
10
*
D05AX52
ATC
calcipotriol, combinations; topical
2.2
8.6
71
329
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
3.7
8.6
26
70
K02.1
ICD-10 Finland
Caries of dentine
1.3
8.6
1545
13788
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.5
8.6
233
1552
SGA01
NOMESCO Finland
Emergency treatment
1.4
8.5
418
3123
R01AD08
ATC
fluticasone; nasal
1.3
8.5
733
5967
N03AX12
ATC
[U] gabapentin; oral
1.4
8.5
350
2538
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
8.5
671
5399
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
20.1
8.5
12
6
S01GX01
ATC
cromoglicic acid; ophthalmic
1.3
8.4
545
4256
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
8.4
202
1308
WX140
NOMESCO Finland
Parabulbar anesthesy
2.0
8.4
87
441
R07.0
ICD-10 Finland
Pain in throat
1.6
8.4
193
1238
M79.6
ICD-10 Finland
Pain in limb
1.3
8.4
1141
9842
A10AA03, ,
ATC
12.8
8.4
14
11
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.7
8.3
153
926
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
8.3
444
3363
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.5
8.3
254
1735
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.4
8.3
55
232
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
+∞
8.3
8
*
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
+∞
8.3
8
*
E03.4
ICD-10 Finland
Atrophy of thyroid (acquired)
+∞
8.3
8
*
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
8.3
455
3463
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
1.9
8.3
104
563
R4110
NOMESCO Finland
Physiotherapy
1.3
8.3
633
5067
XF600
NOMESCO Finland
Bloodpressure measurement
1.8
8.3
123
702
G47.3
ICD-10 Finland
Sleep apnoea
1.4
8.2
465
3560
R60.0
ICD-10 Finland
Localized oedema
1.5
8.2
265
1834
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
8.1
616
4921
H46
ICD-10 Finland
Optic neuritis
4.5
8.1
19
42
A10AB06
ATC
insulin glulisine; parenteral
4.8
8.1
18
38
E05.81
ICD-10 Finland
Overproduction of thyroid-stimulating hormone
33.4
8.1
10
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
33.4
8.1
10
*
O90.5
ICD-10 Finland
Postpartum thyroiditis
33.4
8.1
10
*
J01MA02
ATC
ciprofloxacin; systemic
1.3
8.1
817
6786
J01MA12
ATC
levofloxacin; systemic
1.4
8.0
353
2589
R5110, ,
SPAT
1.6
8.0
185
1189
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
8.0
1413
12544
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
2.2
8.0
67
314
M79.7
ICD-10 Finland
Fibromyalgia
1.9
7.9
92
485
L20
ICPC
Joint symptom/complaint NOS
1.9
7.9
92
486
CD2S4
NOMESCO Finland
Photography of eye
4.4
7.9
19
43
M01CB03
ATC
auranofin; oral
13.1
7.9
13
10
L01
ICPC
Neck symptom/complaint
1.4
7.8
435
3315
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
7.8
99
538
R20.2
ICD-10 Finland
Paraesthesia of skin
1.6
7.8
174
1108
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
3.8
7.8
23
61
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.0
7.7
83
426
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.3
7.7
703
5752
J01FA06
ATC
roxithromycin; oral
1.3
7.7
959
8158
TFP47
NOMESCO Finland
Ablation or modification of the AV-node
4.2
7.7
20
48
XCW12
NOMESCO Finland
Assessment of colour vision
15.1
7.7
12
8
J01AA02
ATC
doxycycline; systemic
1.3
7.7
2015
18677
AN1
HP
Coronary angiography
1.6
7.6
156
973
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
3.6
7.6
24
67
M07.3
ICD-10 Finland
Other psoriatic arthropathies
25.1
7.6
10
*
R13
ICD-10 Finland
Dysphagia
1.7
7.6
142
866
A02BC03
ATC
lansoprazole; oral
1.3
7.5
609
4903
M01AH01
ATC
celecoxib; oral
1.4
7.5
378
2834
E07.89
ICD-10 Finland
Other specified disorders of thyroid
10.0
7.5
14
14
ZX100
NOMESCO Finland
Oral
3.2
7.5
28
87
L04AD01
ATC
ciclosporin; systemic
3.2
7.5
28
87
R74
ICPC
Upper respiratory infection acute
1.3
7.5
921
7818
H25.8
ICD-10 Finland
Other senile cataract
1.6
7.5
188
1232
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
7.1
7.5
17
24
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
7.5
237
1633
R03BA02
ATC
budesonide; inhalant
1.4
7.5
432
3314
ZXD05
NOMESCO Finland
Urgent procedure
1.3
7.4
702
5770
J01FA10
ATC
azithromycin; systemic
1.2
7.4
1508
13547
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
7.4
495
3880
G44.2
ICD-10 Finland
Tension-type headache
1.4
7.4
365
2729
SXC03
NOMESCO Finland
Other oral or dental procedure
3.4
7.4
26
78
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.0
7.3
73
365
L04AA01
ATC
[U] ciclosporin
4.0
7.3
20
50
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
7.3
881
7456
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
7.3
1313
11626
R06AE07
ATC
cetirizine; oral
1.2
7.3
1149
10026
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.4
7.3
297
2146
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
7.3
894
7582
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
+∞
7.3
7
*
108
Kela drug reimbursment
Myasthenia gravis
+∞
7.3
7
*
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
7.3
7
*
H3602, E103,
ICD-10 Finland
+∞
7.3
7
*
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
+∞
7.3
7
*
L03AB08
ATC
interferon beta-1b; parenteral
+∞
7.3
7
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
7.3
466
3628
T99
ICPC
Endocr/metab/nutrit disease other
2.7
7.2
37
138
H02.4
ICD-10 Finland
Ptosis of eyelid
2.1
7.2
66
320
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
7.2
594
4794
S01KA02
ATC
hypromellose; ophthalmic
2.6
7.2
40
156
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
2.5
7.2
44
180
NG1DA
NOMESCO Finland
X-ray of knees
2.8
7.2
34
122
F01
ICPC
Eye pain
2.0
7.2
71
355
M14.5*E03.9
ICD-10 Finland
Arthropathy in hypothyroidism (E00-E03+)
30.1
7.1
9
*
D51.0
ICD-10 Finland
Vitamin B12deficiency anaemia due to intrinsic factor deficiency
20.1
7.1
10
5
E20.9
ICD-10 Finland
Hypoparathyroidism, unspecified
20.1
7.1
10
5
C10AC01
ATC
colestyramine; oral
2.2
7.1
54
243
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.6
7.1
167
1079
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
2.8
7.1
34
123
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.2
7.0
54
245
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
1.9
6.9
80
422
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
6.9
308
2263
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.1
6.9
65
319
K29
ICPC
Cardiovascular sympt/complt other
1.9
6.9
78
409
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
2.6
6.9
37
142
P06
ICPC
Sleep disturbance
1.4
6.9
311
2291
ZXA00
NOMESCO Finland
Right side
1.3
6.9
533
4264
A08
ICPC
Swelling
1.7
6.9
122
734
N01
ICPC
Headache
1.4
6.8
290
2112
I50.0
ICD-10 Finland
Congestive heart failure
1.8
6.8
103
592
R07.3
ICD-10 Finland
Other chest pain
1.5
6.8
231
1614
H50.52
ICD-10 Finland
Exophoria
2.8
6.8
33
120
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.7
6.8
125
759
K74.3
ICD-10 Finland
Primary biliary cirrhosis
40.1
6.8
8
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
3.1
6.7
27
88
A03FA01
ATC
metoclopramide; systemic, rectal
1.3
6.7
532
4265
I50.1
ICD-10 Finland
Left ventricular failure
2.0
6.7
67
336
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
3.9
6.7
19
49
Z00.8
ICD-10 Finland
Other general examinations
1.5
6.7
181
1206
J37.0
ICD-10 Finland
Chronic laryngitis
1.9
6.7
77
406
AQ2
HP
Electrophysiological electroanatomical examination
7.2
6.7
15
21
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
6.7
807
6821
L04AC07
ATC
tocilizumab; parenteral
22.6
6.7
9
*
H53.1
ICD-10 Finland
Subjective visual disturbances
1.6
6.7
164
1070
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
6.7
295
2165
SPAT1283
SPAT
Restricted health certificate
1.3
6.7
459
3611
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.5
6.6
192
1298
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
3.7
6.6
20
54
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.6
6.6
138
866
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
3.6
6.6
21
59
LCA06
NOMESCO Finland
Biopsy of endometrium
1.4
6.6
345
2604
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.4
6.6
266
1921
M01AB55
ATC
diclofenac, combinations; oral
1.7
6.6
120
728
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.6
6.5
130
806
OAB42
NOMESCO Finland
Guidance related to known health problem
10.0
6.5
12
12
SFA10
NOMESCO Finland
One-surface restoration
1.2
6.5
1409
12666
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.4
6.5
285
2087
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.9
6.5
80
432
D06
ICPC
Abdominal pain localized other
1.5
6.5
228
1604
N02BF01
ATC
gabapentin; oral
1.4
6.5
241
1714
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.5
6.5
170
1126
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.8
6.5
87
483
L04
ICPC
Chest symptom/complaint
1.6
6.5
150
966
D09
ICPC
Nausea
1.7
6.4
113
678
C09AA05
ATC
ramipril; oral
1.3
6.4
422
3295
C09DX04
ATC
valsartan and sacubitril; oral
3.9
6.4
18
46
G61.0
ICD-10 Finland
Guillain-Barré syndrome
70.0
6.4
7
*
BA1AN
NOMESCO Finland
Thyroid gland isotope imaging
70.0
6.4
7
*
E89.9
ICD-10 Finland
Postprocedural endocrine and metabolic disorder, unspecified
70.0
6.4
7
*
M13.9
ICD-10 Finland
Arthritis, unspecified
1.6
6.4
137
865
R49.08
ICD-10 Finland
Other specified dysphonia
2.1
6.4
58
281
SPAT1301
SPAT
No procedures
1.3
6.4
659
5464
M01AH05
ATC
etoricoxib; oral
1.2
6.4
1615
14743
250, ,
Kela drug reimbursment
2.5
6.4
37
148
R11
ICD-10 Finland
Nausea and vomiting
1.5
6.3
196
1345
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.5
6.3
177
1189
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
2.9
6.3
28
97
L63.9
ICD-10 Finland
Alopecia areata, unspecified
5.5
6.3
17
31
L03
ICPC
Low back symptom/complaint
1.3
6.3
740
6228
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
6.3
613
5045
TKC20
NOMESCO Finland
Catheterisation of bladder
1.7
6.3
109
652
R4190
NOMESCO Finland
Nutritional therapy
1.9
6.3
78
423
2507B
ICD-9 Finland
Diabetes mellitus, Diabetes with peripheral circulatory disorders[DIABETES MELLITUS CUM COMPLICAT ALIA ,TYYPPI I]
+∞
6.3
6
*
24200
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffusa et exophthalmo. Morbus Basedowi
+∞
6.3
6
*
5790A
ICD-9 Finland
Intestinal malabsorption, Coeliac disease
+∞
6.3
6
*
L04AX07
ATC
dimethyl fumarate; oral
+∞
6.3
6
*
L04AC16
ATC
guselkumab; systemic
+∞
6.3
6
*
O992, E050,
ICD-10 Finland
+∞
6.3
6
*
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.4
6.2
226
1599
-34
ICPC
Blood test
2.0
6.2
63
318
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.7
6.2
117
716
A98
ICPC
Health maint/preventive medicine
1.7
6.2
2717
26547
D07AC01
ATC
betamethasone; topical
1.2
6.2
802
6822
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
2.5
6.2
37
150
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
1.6
6.2
130
818
A43
ICPC
General and Unspecified, Other diagnostic procedure
2.9
6.2
27
93
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
5.3
6.1
17
32
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
1.8
6.1
85
477
SPAT1312
SPAT
General health counselling
1.3
6.1
706
5926
A28
ICPC
Limited function/disability NOS
1.4
6.1
315
2373
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
1.5
6.1
176
1192
K90.9
ICD-10 Finland
Intestinal malabsorption, unspecified
10.0
6.0
11
11
J01CA04
ATC
amoxicillin; systemic
1.3
6.0
2175
20544

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1586
1288
27.00
307.65
8.6
2.9
4.81
4.54
pmol/l
7.15
1511
1175
1513
507
63.54
307.65
4.1
1.4
5.84
2.18
iu/l
21.37
1029
156
826
1569
7.04
307.65
1.5
1.2
224.35
74.35
u/ml
16.85
463
509
2728
19463
15.10
213.66
17.3
3.2
15.76
14.35
pmol/l
152.39
2661
18081
1876
11059
3.10
172.59
7.9
6.2
1.21
1.22
mmol/l
1.47
1644
9579
1676
9819
2.75
146.24
7.0
5.6
1.21
1.22
mmol/l
0.14
1585
9067
1993
13139
2.78
131.02
10.6
8.0
3.81
4.04
e9/l
5.28
1770
11250
498
1611
3.54
126.50
3.2
3.2
62.62
80.95
ng/l
4.40
457
1396
1213
6549
2.50
117.62
5.4
3.7
7.40
7.40
ph
1.13
928
4540
2749
22899
10.54
106.38
18.9
4.2
1.71
1.81
mu/l
2.68
2680
21466
1647
10812
2.27
94.75
2.9
2.2
76.11
77.28
nmol/l
0.98
1541
9905
1752
11868
2.27
92.34
6.6
4.5
0.19
0.18
e9/l
0.38
1546
10283
1701
11434
2.24
90.66
6.4
4.3
0.04
0.04
e9/l
0.25
1477
9698
1696
11401
2.23
90.18
6.4
4.3
0.56
0.55
e9/l
0.34
1477
9672
1592
10439
2.21
90.04
6.6
4.4
2.85
2.78
%
0.60
1494
9724
2314
17784
2.71
89.95
9.9
6.8
79.06
77.28
u/l
1.19
2237
16814
1588
10457
2.19
88.13
6.6
4.5
0.67
0.67
%
0.01
1487
9723
1623
10787
2.20
87.88
6.6
4.4
28.31
28.66
%
0.72
1538
10197
1587
10457
2.19
87.81
6.6
4.5
8.67
8.47
%
2.12
1485
9762
1598
10577
2.19
87.16
6.4
4.4
56.55
56.73
%
0.24
1525
10062
1719
11710
2.21
87.13
6.4
4.4
1.86
1.94
e9/l
1.96
1532
10240
79
61
13.30
82.95
1.6
1.7
15.81
14.04
pmol/l
1.47
71
51
1285
8284
2.02
69.73
3.3
3.5
2.34
2.36
mmol/l
8.95
1184
7598
2236
17677
2.30
68.49
4.9
3.3
11.86
11.00
mm/h
2.24
2126
16614
961
5911
1.95
56.74
1.5
1.3
1.81
1.23
u/ml
0.89
254
1629
831
4919
1.98
54.48
1.6
1.4
2.17
2.26
g/l
0.93
510
3052
1760
13366
1.85
51.58
5.2
4.2
6.54
6.41
mmol/l
1.67
1678
12489
1081
7087
1.85
51.23
7.5
5.5
—
—
—
0
0
441
2095
2.31
51.04
2.2
2.1
374.52
383.93
nmol/l
0.45
411
1951
565
3050
2.07
47.06
1.4
1.3
539.39
366.48
titre
1.38
132
512
336
1464
2.47
47.05
2.3
1.4
—
—
—
0
0
1361
9785
1.76
45.72
4.8
4.3
36.14
36.27
g/l
0.38
1270
9203
1396
10242
1.72
42.50
13.2
8.8
0.00
0.00
e9/l
0.36
1142
8165
97
220
4.53
39.59
3.9
6.6
52.88
63.62
u/ml
0.14
36
68
856
5565
1.77
39.38
2.5
2.1
2.66
2.73
mg/l
0.43
760
4787
2675
24357
3.07
37.89
20.2
14.4
139.74
139.78
mmol/l
0.49
2636
23862
2677
24417
3.07
37.17
20.5
14.5
3.93
3.94
mmol/l
0.73
2637
23854
1566
12119
1.66
36.82
6.3
6.2
10.75
10.84
umol/l
0.09
1502
11530
591
3551
1.84
34.73
3.5
3.2
0.81
0.82
mmol/l
2.17
557
3349
849
5670
1.71
34.64
3.4
2.9
1300.30
1027.68
ng/l
1.08
730
4804
468
2609
1.95
34.63
5.2
4.8
1.07
1.04
mmol/l
1.55
429
2401
1571
12382
1.61
32.52
3.7
2.9
102.13
95.91
ug/l
0.56
1495
11724
459
2625
1.89
31.21
3.2
2.7
3.90
4.64
e9/l
2.13
401
2302
1293
9852
1.58
29.94
2.2
2.0
98.87
98.30
pmol/l
0.15
706
4943
1269
9642
1.58
29.64
15.0
11.8
1.23
1.19
inr
1.77
1078
7908
2634
24187
2.44
29.52
17.4
12.2
19.32
22.92
mg/l
7.80
2218
19294
285
1402
2.15
29.49
2.4
2.4
10.41
10.47
g/l
0.10
265
1277
721
4811
1.67
28.55
1.4
1.3
27.40
19.43
iu/ml
0.90
209
1369
667
4368
1.69
28.32
1.3
1.3
5.35
2.32
u/ml
1.49
239
1741
514
3166
1.76
27.10
2.7
2.3
2.43
2.40
g/l
0.80
476
2944
175
727
2.50
26.81
1.7
1.3
5.38
6.02
iu/ml
0.15
28
142
545
3445
1.72
26.12
2.7
2.3
13.69
13.77
umol/l
0.09
506
3225
1094
8203
1.55
26.06
3.9
3.2
63.00
34.92
ng/l
0.77
673
4915
308
1636
1.99
25.80
4.0
4.0
0.03
0.58
%
1.09
67
380
356
1995
1.90
25.44
4.6
3.9
7.38
7.35
ph
3.29
287
1379
465
2848
1.76
24.82
2.8
2.3
22.02
22.95
%
0.83
429
2656
363
2069
1.87
24.57
1.2
1.1
—
—
—
0
0
2479
22520
1.86
24.48
6.7
5.2
39.11
37.82
mmol/mol
10.64
2347
21285
150
605
2.56
24.44
1.3
1.2
109.26
2.03
u/ml
—
7
19
2724
25675
3.04
24.19
15.9
9.4
24.46
24.73
u/l
0.39
2688
24987
298
1601
1.96
24.10
3.9
3.9
0.06
0.14
%
1.55
68
401
981
7289
1.53
23.80
2.7
2.4
78.78
71.24
u/l
0.11
919
6761
306
1667
1.94
23.75
3.8
3.8
1.06
0.97
%
0.15
74
464
292
1572
1.96
23.45
3.6
3.7
0.80
0.75
%
0.12
73
439
136
538
2.61
23.06
1.3
1.2
33.31
2.01
u/ml
—
7
29
135
537
2.59
22.64
1.3
1.2
31.27
7.01
u/ml
0.79
14
55
1055
8027
1.50
22.56
2.3
2.1
—
—
—
0
0
2726
25786
2.96
22.45
22.8
15.5
71.47
70.88
umol/l
0.48
2701
25480
298
1644
1.91
22.22
3.9
3.7
1.22
1.23
mmol/l
2.59
270
1411
731
5198
1.55
21.20
4.6
3.2
—
—
—
0
0
220
1112
2.06
21.05
1.9
1.8
1.23
1.41
g/l
1.18
207
1011
466
2983
1.67
20.88
2.1
1.3
145.29
87.41
ug/g
1.44
369
2270
1425
11624
1.46
20.87
2.7
2.6
—
—
estimate
—
0
0
118
476
2.54
19.25
1.2
1.1
41.74
18.48
u/ml
—
10
36
654
4623
1.54
19.20
2.8
2.8
2.44
2.45
mmol/l
0.61
571
4163
822
6105
1.49
19.04
1.7
1.6
20.43
20.50
nmol/l
0.05
723
5189
141
622
2.33
18.93
1.3
1.1
—
—
—
0
0
603
4206
1.55
18.74
4.3
3.3
207.27
337.95
ng/l
0.62
433
2873
382
2389
1.69
18.55
1.3
1.2
—
—
—
0
0
56
150
3.79
18.42
5.3
8.4
49.56
129.06
ug/l
0.32
42
100
763
5626
1.49
18.17
1.9
1.7
0.96
1.04
mg/l
0.43
565
4350
1832
15912
1.44
17.64
5.2
4.3
1538.52
2276.54
e6/l
0.19
23
175
332
2025
1.73
17.63
2.7
2.2
1.71
1.76
%
0.35
303
1811
122
523
2.39
17.48
1.6
1.3
0.23
0.24
g/l
0.72
114
499
2514
23350
1.73
17.48
5.3
4.6
5.84
5.73
mmol/l
4.18
2373
21774
466
3110
1.60
17.42
1.8
1.7
1065.04
1164.16
nmol/l
1.88
375
2353
1506
12665
1.41
17.21
4.0
3.4
0.00
4.06
estimate
1.83
317
2447
1492
12531
1.41
17.15
3.9
3.4
0.00
0.00
estimate
1.08
314
2381
1515
12763
1.41
17.08
4.0
3.5
0.16
0.14
estimate
0.05
307
2346
1959
17296
1.44
16.72
3.5
3.0
42.06
40.37
u/l
0.35
1866
16434
874
6720
1.44
16.42
2.3
2.0
218.93
197.35
u/l
0.10
832
6378
1288
10615
1.39
16.18
2.2
2.0
—
—
—
0
0
571
4054
1.51
16.07
3.2
2.6
498.49
522.74
mosm/kgh2o
1.94
502
3509
257
1495
1.79
16.05
2.4
2.8
65.48
66.87
g/l
2.31
241
1371
793
6009
1.45
16.05
2.2
2.1
—
—
—
0
0
793
6025
1.44
15.77
4.3
3.5
91.95
94.19
%
1.72
774
5907
1062
8506
1.40
15.64
4.4
3.4
63.18
84.28
e6/l
0.95
737
5656
92
368
2.55
15.33
2.9
2.4
58.58
59.16
%
0.16
92
368
121
548
2.26
15.31
1.7
1.3
1.18
1.23
g/l
1.12
112
521
802
6163
1.42
14.81
3.6
2.8
0.27
0.41
e6/l
1.69
588
4302
908
7135
1.40
14.74
3.7
2.9
25.87
80.36
e6/l
1.93
694
5204
1019
8177
1.39
14.55
3.4
3.0
29.49
31.03
u/l
0.73
966
7774
135
653
2.12
14.52
1.3
1.2
—
—
—
0
0
100
427
2.39
14.50
2.0
2.0
4.93
5.25
mmol/24h
0.47
85
383
245
1454
1.75
14.27
3.0
2.8
187.53
159.24
ng/l
0.63
221
1320
467
3260
1.52
14.06
1.3
1.2
—
—
—
0
0
400
2701
1.56
14.02
1.6
1.6
—
—
—
0
0
44
121
3.68
14.00
1.1
1.1
0.82
0.10
nmol/l
—
10
15
2255
20705
1.45
13.45
25.2
15.2
13.54
13.47
%
2.01
2235
20426
208
1205
1.78
13.16
1.1
1.1
97.14
203.80
titre
—
7
25
733
5644
1.40
13.10
2.5
2.3
315.72
319.91
umol/l
0.55
645
5050
577
4265
1.44
12.93
1.7
1.7
—
—
—
0
0
400
2750
1.53
12.86
2.8
2.6
7.32
7.28
umol/l
0.01
346
2378
282
1800
1.63
12.48
1.4
1.5
—
—
—
0
0
628
4745
1.42
12.41
2.9
2.3
6.37
7.30
e6/l
0.91
575
4263
245
1513
1.68
12.33
2.4
2.3
73.15
69.96
e9/l
0.48
171
1092
2759
26759
2.78
12.27
31.5
18.8
263.06
260.06
e9/l
1.85
2724
26242
757
5919
1.38
12.20
3.6
2.7
—
5.18
estimate
—
0
21
2759
26764
2.77
12.17
31.3
18.8
90.63
90.73
fl
0.60
2741
26519
2759
26764
2.77
12.17
31.3
18.8
30.10
30.18
pg
1.61
2741
26520
2759
26766
2.76
12.13
31.9
19.1
40.46
40.70
%
0.35
2741
26506
2759
26768
2.76
12.09
31.4
18.8
4.50
4.47
e12/l
3.15
2716
26178
2759
26769
2.76
12.07
31.5
18.9
6.60
6.62
e9/l
0.15
2717
26163
151
815
1.90
11.99
1.3
1.1
0.36
0.90
u/ml
—
9
64
2759
26775
2.74
11.95
31.6
18.9
134.81
134.19
g/l
1.87
2744
26532
79
334
2.40
11.77
1.7
1.6
0.74
0.76
g/l
0.07
60
262
708
5505
1.38
11.73
4.4
3.9
—
—
—
0
0
111
547
2.07
11.43
2.4
2.3
10.27
12.16
mg/l
1.53
104
513
198
1180
1.73
11.36
3.2
3.3
7.41
7.42
ph
0.51
158
983
859
6927
1.35
11.19
3.6
2.9
0.23
0.18
estimate
0.08
274
1890
67
269
2.53
11.16
2.2
1.5
47.09
27.02
ng/l
0.77
67
269
201
1221
1.70
10.76
3.4
3.3
5.23
5.18
kpa
0.31
194
1168
2554
24283
1.57
10.59
5.2
4.6
4.73
4.81
mmol/l
4.06
2417
23006
816
6579
1.34
10.51
4.4
3.6
6.66
7.09
mg/mmol
0.11
480
3822
2430
22879
1.46
10.45
4.2
3.9
1.24
1.24
mmol/l
0.11
2267
21381
1212
10346
1.30
10.31
2.0
1.8
1.31
1.35
mmol/l
0.96
1029
8934
1184
10081
1.30
10.25
3.4
3.1
6.19
6.21
ph
0.28
658
5728
882
7225
1.32
10.10
3.6
3.0
6.94
7.40
mmol/l
2.54
753
6148
113
587
1.96
10.09
2.8
3.1
1.40
2.19
index
1.05
53
312
299
2038
1.52
9.92
2.3
2.0
0.21
0.22
g/l
0.45
278
1931
2539
24167
1.53
9.82
5.1
4.5
1.51
1.53
mmol/l
2.50
2392
22774
876
7193
1.32
9.80
3.1
2.6
0.00
0.05
—
6
151
83
389
2.17
9.77
2.0
1.5
5682.43
9532.46
e6/l
1.42
60
269
45
160
2.84
9.54
1.1
1.1
—
—
—
0
0
283
1928
1.52
9.41
3.5
3.1
7.38
7.38
ph
0.85
155
1018
108
567
1.94
9.37
1.2
1.2
93.33
120.33
titre
—
9
61
650
5143
1.34
9.33
2.0
2.0
—
—
—
0
0
57
233
2.48
9.21
1.3
1.2
—
—
—
0
0
279
1904
1.52
9.20
3.3
3.1
5.86
5.81
kpa
0.39
265
1852
795
6494
1.31
9.10
3.8
3.0
32.72
40.12
mg/l
0.50
492
3859
83
401
2.10
9.07
1.3
1.3
160.82
156.26
au/ml
0.14
27
114
87
429
2.06
9.01
1.3
1.3
—
—
—
0
0
2567
24554
1.53
8.99
5.9
5.1
2.80
2.84
mmol/l
1.49
2416
23163
475
3601
1.38
8.92
3.4
2.6
4.11
3.80
e6/l
0.19
239
1628
272
1861
1.51
8.86
3.3
3.1
1.67
1.90
mmol/l
0.38
224
1642
880
7310
1.30
8.84
3.2
2.9
—
—
—
0
0
114
622
1.87
8.83
3.1
2.7
25.37
24.90
mmol/l
0.51
114
610
321
2277
1.46
8.74
7.4
7.1
12.23
13.17
kpa
2.58
311
2194
321
2277
1.46
8.74
7.4
7.1
5.11
5.11
kpa
0.00
309
2194
316
2252
1.45
8.39
7.2
7.1
0.92
0.93
mmol/l
0.02
255
1860
121
688
1.79
8.23
1.1
1.1
3.85
3.50
eliau/ml
0.05
11
92
52
216
2.43
8.16
1.4
1.4
6.61
6.53
g/l
0.07
36
158
52
216
2.43
8.16
1.4
1.4
0.31
0.41
g/l
2.09
36
157
52
216
2.43
8.16
1.4
1.4
2.82
2.99
g/l
0.34
35
159
40
147
2.75
8.03
1.1
1.1
—
—
—
0
0
128
746
1.75
8.01
1.9
1.5
1.45
1.53
g/l
0.44
108
644
401
3010
1.39
7.94
2.1
1.8
—
—
—
0
0
128
748
1.75
7.94
2.2
2.5
3.80
3.70
g/l
0.17
123
687
128
748
1.75
7.94
2.2
2.5
4.15
4.28
g/l
1.20
123
687
51
213
2.42
7.92
1.5
1.4
—
—
—
0
0
352
2587
1.41
7.89
2.0
1.6
—
—
—
0
0
124
724
1.75
7.72
1.2
1.2
—
—
—
0
0
313
2276
1.42
7.44
7.4
7.1
7.42
7.42
ph
0.16
167
1198
109
620
1.79
7.43
3.0
3.1
7.41
7.41
ph
0.14
109
615
497
3897
1.33
7.42
3.2
2.5
1.30
1.26
e6/l
0.04
260
1921
258
1822
1.46
7.18
7.1
6.7
1.39
1.26
mmol/l
0.64
250
1788
172
1117
1.58
7.12
3.6
3.3
24.34
24.42
mmol/l
0.11
172
1107
196
1312
1.53
7.09
7.2
7.1
24.88
24.86
mmol/l
0.02
196
1307
560
4497
1.31
7.02
1.7
1.6
55901040.90
49488219.72
pmol/l
0.08
483
3807
112
654
1.74
7.00
1.4
1.4
278.96
301.46
ug/g
0.58
66
361
136
841
1.65
6.89
3.1
3.3
—
—
—
0
0
273
1967
1.43
6.83
7.7
7.6
95.20
95.95
%
1.13
261
1903
41
168
2.46
6.68
1.6
1.4
47.81
61.75
%
1.28
31
100
249
1773
1.44
6.64
4.1
3.5
—
—
—
0
0
316
2348
1.39
6.63
3.0
2.2
38.43
36.20
u/l
0.16
261
1964
17
41
4.17
6.54
1.1
1.1
—
—
—
0
0
365
2784
1.36
6.51
1.5
1.4
—
—
—
0
0
110
654
1.71
6.48
1.9
2.2
255.22
847.41
ug/l
1.11
98
615
241
1714
1.44
6.47
2.3
2.4
15.77
20.60
au/ml
0.58
23
234
780
6596
1.25
6.37
4.0
3.5
0.00
0.01
estimate
2.41
308
2250
223
1568
1.46
6.36
1.2
1.3
66.28
47.63
au/ml
0.37
11
115
107
636
1.71
6.31
2.3
2.5
9.60
9.95
g/l
0.52
101
569
66
338
1.98
6.27
4.7
3.4
0.77
0.79
nmol/l
0.14
57
287
62
312
2.01
6.19
2.5
1.3
64.36
47.03
mu/l
0.57
56
282
83
464
1.81
6.06
2.0
2.2
130.23
128.61
g/l
0.27
61
364
1091
9611
1.22
6.00
3.9
3.3
1.92
0.35
estimate
0.38
263
1927
873
7526
1.23
5.90
1.6
1.5
—
—
—
0
0
258
1891
1.40
5.87
8.2
7.9
121.64
121.38
g/l
0.07
250
1842
352
2712
1.34
5.87
5.0
4.5
32.38
32.62
%
0.16
255
1806
109
675
1.64
5.55
3.1
3.4
1698.31
271.30
mg/l
0.47
51
260
10
10
10.03
5.53
10.6
16.6
5.12
4.71
mmol/l
—
10
10
70
383
1.85
5.51
3.8
3.3
—
—
—
0
0
51
250
2.06
5.50
2.9
3.4
1.14
1.67
%
0.84
44
226
224
1621
1.41
5.50
7.8
6.5
8.99
8.76
mmol/l
0.19
215
1563
48
231
2.10
5.44
1.0
1.1
—
—
—
0
0
265
1982
1.37
5.35
2.9
2.3
6.12
6.12
ph
0.03
170
1291
37
162
2.30
5.28
1.9
1.6
120.56
88.38
ng/l
0.27
37
162
17
49
3.48
5.17
1.1
1.3
11.34
14.93
pmol/l
—
7
18
71
400
1.80
5.11
1.2
1.2
270.72
238.94
u/ml
0.47
46
251
136
909
1.52
5.03
1.1
1.1
—
—
—
0
0
35
153
2.30
5.03
3.0
3.7
—
—
—
0
0
35
154
2.29
4.96
2.8
3.2
60.07
58.04
%
0.29
29
137
427
3460
1.28
4.89
1.2
1.3
—
—
—
0
0
64
355
1.82
4.86
3.5
3.4
8.82
8.78
kpa
0.06
64
350
29
119
2.45
4.79
1.2
1.2
—
18.37
—
0
6
29
119
2.45
4.79
1.5
1.3
41.38
30.88
%
0.59
19
65
33
144
2.31
4.77
1.3
1.2
—
—
—
0
0
141
961
1.49
4.77
2.0
1.9
0.00
0.80
estimate
0.51
33
322
217
1602
1.38
4.77
2.9
2.7
4.59
4.52
kpa
0.17
205
1556
230
1717
1.37
4.72
9.0
7.9
—
—
—
0
0
210
1548
1.39
4.66
2.2
2.2
9.65
6.38
ug/l
0.56
171
1369
63
353
1.80
4.65
3.5
3.4
4.94
4.99
kpa
0.27
63
348
63
353
1.80
4.65
3.5
3.4
2.47
2.51
mmol/l
0.05
48
221
66
376
1.77
4.61
2.4
2.5
16.75
16.45
%
0.37
66
367
32
140
2.30
4.61
1.1
1.1
—
—
—
0
0
38
179
2.14
4.60
6.9
3.4
7.35
6.63
mmol/l
0.63
33
147
33
148
2.24
4.50
1.2
1.1
226.67
91.54
titre
—
9
13
105
681
1.56
4.48
2.1
1.8
1.34
1.51
ug/l
0.07
90
613
41
202
2.04
4.43
1.2
1.2
108.95
111.57
pmol/l
0.13
41
202
139
962
1.47
4.38
1.2
1.2
—
—
—
0
0
79
483
1.65
4.31
1.6
1.4
41.29
42.37
e6/l
0.01
58
347
276
2149
1.32
4.29
1.5
1.4
—
—
—
0
0
102
665
1.55
4.27
2.7
3.4
25.04
24.95
mmol/l
0.09
93
614
94
603
1.58
4.23
3.3
3.5
42.12
56.36
mg/l
0.51
76
523
15
46
3.27
4.18
3.7
2.4
0.61
0.62
mmol/l
0.21
15
46
48
256
1.89
4.17
1.3
1.2
—
—
—
0
0
183
1345
1.39
4.16
2.4
2.2
4660.08
6229.63
u/l
0.34
84
555
56
317
1.78
4.04
2.6
2.3
41.04
85.13
ug/min
0.60
35
181
266
2083
1.31
3.98
2.0
2.0
0.03
0.02
estimate
0.09
38
408
79
495
1.61
3.94
1.7
1.5
776.23
1994.49
e6/l
0.88
64
380
155
1121
1.41
3.89
2.5
2.3
—
—
—
0
0
61
360
1.71
3.83
1.3
1.3
67.06
60.62
mmol/l
0.49
50
284
92
604
1.54
3.78
3.3
3.5
37.24
62.54
mg/l
0.68
74
523
14
44
3.19
3.77
4.4
4.0
—
—
—
0
0
50
281
1.79
3.72
1.3
1.4
—
—
nmol/l
—
0
0
260
2051
1.29
3.70
1.5
1.4
24.56
29.38
iu/l
1.90
222
1789
74
465
1.61
3.67
1.6
1.4
—
—
—
0
0
24
104
2.32
3.59
3.0
2.8
—
—
—
0
0
28
130
2.17
3.57
1.5
1.2
32169.61
171792.13
e6/l
1.05
18
89
60
362
1.67
3.50
1.3
1.2
2.50
4.35
u/ml
1.16
32
144
41
221
1.87
3.50
1.8
2.2
—
—
—
0
0
23
99
2.33
3.50
1.1
1.3
142.26
150.21
mmol/24h
0.20
23
99
15
52
2.89
3.46
1.0
1.4
—
—
—
0
0
24
109
2.21
3.25
1.7
1.3
5.07
5.41
u/l
0.19
19
92
25
116
2.17
3.22
2.9
2.6
—
—
—
0
0
207
1616
1.30
3.21
2.6
2.1
0.32
0.50
e6/l
0.86
197
1524
57
349
1.65
3.18
1.3
1.4
0.12
0.46
nmol/l
—
5
20
225
1781
1.29
3.15
1.5
1.3
177.22
181.46
u/ml
0.04
215
1655
83
557
1.51
3.14
1.2
1.3
—
—
—
0
0
62
394
1.59
3.00
1.1
1.0
2.60
2.04
eliau/ml
0.27
24
201
29
147
1.98
2.99
1.4
1.1
41.95
36.13
mg/l
0.36
23
130
82
555
1.49
2.99
1.5
1.3
504.24
503.80
mg/l
0.00
76
531
381
3221
1.21
2.97
2.4
2.0
29.80
29.27
s
0.83
366
3133
41
234
1.76
2.96
2.0
1.5
—
—
—
0
0
50
302
1.67
2.96
1.4
1.3
341.30
318.48
pmol/l
0.15
44
266
47
280
1.69
2.93
2.2
1.7
1.50
1.66
mmol/l
0.87
47
273
163
1255
1.32
2.83
9.7
9.0
0.59
0.65
%
1.30
163
1250
79
538
1.48
2.82
3.2
3.3
1.20
3.67
ratio
1.82
39
301
146
1111
1.33
2.75
1.6
1.7
271.10
294.19
mu/l
0.61
127
1014
159
1228
1.31
2.71
3.2
2.6
131.52
130.40
g/l
0.25
149
1192
27
139
1.95
2.70
1.1
1.1
261.76
243.60
mg/l
0.19
21
126
35
197
1.79
2.68
2.3
2.5
28.45
28.58
mg/l
0.01
29
127
31
168
1.85
2.67
1.0
1.1
—
—
—
0
0
167
1307
1.30
2.59
9.4
8.8
1.37
1.32
%
0.29
167
1301
215
2640
0.80
2.58
1.7
1.7
3.54
3.50
mmol/l
0.13
137
1787
62
412
1.52
2.52
2.2
2.2
5.09
4.54
umol/l
0.28
41
296
23
115
2.01
2.50
1.1
1.3
126.09
134.39
nmol/l
0.41
23
115
152
1181
1.30
2.50
1.4
1.4
—
—
—
0
0
167
1314
1.29
2.50
9.7
8.8
94.20
94.10
%
0.10
167
1308
46
286
1.62
2.48
1.3
1.3
0.17
0.25
nmol/l
0.56
34
222
386
3327
1.19
2.45
1.5
1.5
—
—
—
0
0
17
76
2.24
2.44
2.4
1.5
—
—
—
0
0
55
361
1.53
2.38
1.2
1.1
—
—
—
0
0
149
1164
1.30
2.37
6.1
6.4
24.64
24.56
mmol/l
0.11
141
1104
35
207
1.70
2.30
1.4
1.1
0.37
0.96
u/ml
0.67
23
113
5
153
0.33
2.28
33.4
15.0
800.00
884.40
nmol/l
—
5
147
99
734
1.36
2.27
1.5
1.4
11.76
12.30
u/l
0.14
85
607
43
270
1.60
2.26
2.3
2.3
—
—
—
0
0
112
847
1.34
2.26
5.1
4.6
1.63
1.60
%
0.18
107
791
9
29
3.11
2.22
1.1
1.0
—
—
—
0
0
82
592
1.40
2.21
5.7
5.4
1.21
1.26
mmol/l
0.28
76
521
52
344
1.52
2.19
1.2
1.8
436.49
336.59
mu/l
0.37
37
278
87
636
1.38
2.18
1.1
1.1
—
—
—
0
0
41
257
1.60
2.18
1.5
1.4
—
—
—
0
0
41
257
1.60
2.18
1.5
1.4
—
—
—
0
0
41
257
1.60
2.18
1.5
1.4
—
—
—
0
0
41
257
1.60
2.18
1.5
1.4
—
—
—
0
0
21
108
1.95
2.15
1.3
1.2
0.61
0.51
ratio
0.62
14
70
16
74
2.17
2.14
3.1
6.5
100.82
73.21
mg/l
0.49
11
43
130
1013
1.30
2.14
1.9
2.2
11.30
11.18
nmol/l
0.05
115
922
227
1889
1.22
2.13
1.2
1.2
—
—
—
0
0
245
2903
0.83
2.11
1.3
1.3
—
—
—
0
0
21
109
1.93
2.10
1.3
1.6
1.86
1.98
umol/l
0.35
21
97
298
3466
0.84
2.09
1.9
1.9
3.55
3.35
ratio
0.73
220
2584
18
89
2.03
2.05
2.7
2.6
179.56
426.68
e6/l
0.39
18
84
364
3175
1.17
2.03
1.7
1.8
—
—
—
0
0
11
44
2.51
2.01
1.4
1.1
—
—
—
0
0
18
91
1.98
1.95
1.8
1.5
130.17
79.49
nmol/24h
0.51
18
91
10
39
2.57
1.94
1.2
1.1
—
—
—
0
0
51
348
1.47
1.90
2.2
1.7
—
—
—
0
0
39
251
1.56
1.89
1.8
1.8
—
1742.22
—
0
9
73
534
1.38
1.87
1.4
1.3
30.33
27.11
u/l
0.32
55
441
93
708
1.32
1.85
1.5
1.3
—
—
—
0
0
36
229
1.58
1.84
1.6
1.6
275.83
279.24
mosm/kgh2o
0.33
24
182
26
152
1.72
1.83
1.6
1.1
—
—
—
0
0
210
1766
1.20
1.80
1.5
1.6
962.80
1036.06
mu/l
0.51
163
1456
19
101
1.89
1.80
1.1
1.1
152.35
181.69
iu/ml
0.36
19
101
18
94
1.92
1.80
2.3
2.4
41.56
41.75
%
—
9
49
16
80
2.01
1.80
1.1
1.8
39.46
40.65
g/l
0.33
16
80
139
1121
1.25
1.78
3.2
3.1
1.02
1.02
ratio
1.10
122
994
11
47
2.35
1.77
1.1
1.0
—
—
—
0
0
11
47
2.35
1.77
1.1
1.0
—
—
—
0
0
11
47
2.35
1.77
1.1
1.0
—
—
—
0
0
103
805
1.29
1.71
3.1
3.6
175.39
2028.19
u/ml
0.88
81
703
55
390
1.42
1.71
3.3
1.7
0.85
0.89
nmol/l
0.14
43
349
116
925
1.27
1.66
2.2
1.8
21.27
20.81
s
0.22
107
801
17
90
1.89
1.65
1.1
1.0
1423.47
1295.60
miu/ml
0.21
17
90
25
150
1.67
1.63
1.5
1.4
—
—
—
0
0
46
320
1.44
1.60
1.1
1.1
69.68
3.42
iu/ml
—
5
62
55
396
1.40
1.59
1.1
1.2
—
—
—
0
0
10
43
2.33
1.58
1.7
1.5
—
—
—
0
0
80
612
1.32
1.58
1.1
1.1
—
—
—
0
0
56
405
1.39
1.58
2.4
2.9
35.88
34.02
umol/l
0.15
49
367
56
763
0.73
1.57
14.9
7.3
—
—
—
0
0
79
605
1.31
1.55
1.9
1.9
—
—
—
0
0
13
64
2.04
1.54
1.8
2.2
26.31
32.52
%
0.86
13
64
129
1052
1.24
1.54
1.5
1.7
14.02
12.79
u/ml
0.08
26
291
14
71
1.98
1.53
2.6
2.4
—
—
—
0
0
11
51
2.16
1.50
1.3
1.2
42.52
37.40
g/l
—
6
26
28
178
1.58
1.48
1.3
1.4
—
—
—
0
0
77
593
1.31
1.47
3.1
2.9
1.52
1.35
mg/l
1.21
72
549
128
1050
1.23
1.46
1.4
1.5
62.20
59.81
ug/l
0.21
101
859
98
780
1.27
1.45
5.6
4.8
0.82
0.89
%
0.85
93
725
160
1344
1.20
1.44
1.3
1.2
—
—
—
0
0
6
22
2.73
1.43
1.7
1.1
—
—
—
0
0
6
22
2.73
1.43
1.0
1.1
—
—
—
0
0
17
95
1.79
1.43
2.6
2.3
0.76
0.76
e9/l
0.01
17
89
27
172
1.58
1.43
1.1
1.1
365.59
384.27
nmol/l
0.18
22
158
9
40
2.25
1.40
1.9
1.4
—
—
—
0
0
51
373
1.37
1.38
1.1
1.1
—
—
—
0
0
103
831
1.25
1.38
2.9
2.7
25.01
25.46
mmol/l
0.67
95
798
6
24
2.50
1.30
3.5
3.1
0.17
0.18
%
—
6
24
28
185
1.52
1.29
3.3
2.5
—
—
—
0
0
16
91
1.76
1.29
1.2
1.2
7.47
7.40
ph
—
10
60
24
153
1.57
1.28
1.4
1.2
13.63
9.30
mm/h
0.91
24
153
5
18
2.78
1.28
1.2
1.4
0.16
0.16
umol/l
—
5
18
270
2393
1.14
1.27
3.6
4.2
72.37
34.51
ug/l
0.25
211
1878
52
388
1.35
1.26
1.1
1.1
—
—
—
0
0
18
107
1.69
1.25
1.3
1.2
—
—
—
0
0
31
212
1.47
1.22
1.3
1.4
1019.79
1856.37
e6/l
1.78
24
141
8
37
2.17
1.21
1.0
2.1
—
—
—
0
0
24
156
1.54
1.20
1.2
1.1
1.05
1.05
ratio
0.02
19
124
6
26
2.31
1.18
1.5
1.2
5.47
1330005.80
nmol/l
—
6
20
28
189
1.49
1.18
1.3
1.3
19251.30
58843.41
e6/l
0.71
20
96
25
166
1.51
1.15
2.1
1.6
6.67
6.24
mmol/l
0.33
20
116
24
158
1.52
1.14
1.0
1.0
—
—
—
0
0
20
126
1.59
1.14
14.7
14.3
0.66
0.61
mmol/l
0.39
20
117
14
80
1.75
1.12
1.0
1.0
—
—
—
0
0
17
103
1.65
1.12
1.5
2.6
179.67
164.06
umol/l
—
9
50
8
40
2.00
1.12
5.9
7.5
7.05
5.39
kpa
—
8
40
7
31
2.26
1.10
2.0
1.3
—
—
—
0
0
202
1776
1.15
1.10
3.0
3.1
0.78
0.74
ug/l
0.23
118
1080
16
96
1.67
1.10
2.0
2.1
16.75
16.67
%
0.03
16
96
218
1931
1.14
1.07
3.0
3.6
66.55
61.98
u/ml
0.08
211
1870
87
714
1.23
1.05
1.1
1.1
—
—
—
0
0
36
262
1.38
1.05
2.0
1.4
—
—
—
0
0
59
467
1.27
0.99
4.4
4.0
—
—
—
0
0
130
1117
1.17
0.98
2.0
1.8
—
—
—
0
0
12
69
1.74
0.96
1.1
1.2
27.83
27.73
s
0.02
12
69
65
525
1.24
0.93
1.1
1.1
—
—
—
0
0
321
2946
1.10
0.88
5.1
5.1
2.14
2.34
ug/l
0.30
280
2652
8
43
1.86
0.87
1.0
1.0
—
—
—
0
0
40
310
1.29
0.82
1.7
1.7
—
—
—
0
0
64
526
1.22
0.81
1.1
1.1
—
—
—
0
0
28
207
1.36
0.79
3.4
3.1
15.86
13.64
index
0.32
21
126
592
5616
1.07
0.74
4.2
3.5
1.02
1.58
kg/l
0.80
412
3598
25
184
1.36
0.73
1.2
1.1
—
—
—
0
0
62
515
1.21
0.73
1.1
1.1
15.44
12.68
au/ml
0.13
13
147
7
39
1.80
0.72
1.3
1.1
6.53
6.42
mg/g
—
7
39
147
1316
1.12
0.68
1.1
1.1
—
—
—
0
0
30
232
1.30
0.66
2.2
3.0
—
—
—
0
0
7
44
1.59
0.65
1.0
1.2
—
—
—
0
0
32
251
1.28
0.64
1.1
1.2
—
—
—
0
0
98
860
1.14
0.63
1.5
1.5
—
—
—
0
0
55
461
1.20
0.62
3.7
3.0
18.13
25.34
mg/l
1.22
36
304
5
30
1.67
0.61
1.6
1.8
—
—
—
0
0
110
978
1.13
0.59
2.0
1.8
—
—
—
0
0
116
1038
1.12
0.57
1.5
1.9
—
—
—
0
0
6
36
1.67
0.56
1.2
1.3
58.83
66.72
ug/l
—
6
36
68
588
1.16
0.55
1.1
1.1
1.79
4.91
u/ml
4.01
43
301
66
570
1.16
0.55
1.1
1.1
0.44
1.16
u/ml
1.54
34
226
23
177
1.30
0.54
1.1
1.2
—
—
—
0
0
101
1131
0.89
0.54
1.0
1.1
0.58
0.64
ratio
0.50
14
132
65
562
1.16
0.53
1.1
1.1
1.70
1.59
u/ml
0.04
38
255
21
160
1.31
0.53
2.2
2.6
44.27
20.86
mg/l
0.39
12
111
125
1130
1.11
0.53
1.5
1.9
—
—
—
0
0
93
826
1.13
0.53
1.4
1.5
1.22
1.29
mm
0.79
63
582
19
143
1.33
0.52
1.3
1.5
70.63
72.16
umol/l
0.18
19
143
29
232
1.25
0.52
1.1
1.1
—
—
—
0
0
106
951
1.12
0.51
1.3
1.7
0.25
0.32
mg/l
0.66
34
443
14
100
1.40
0.51
1.7
1.7
—
—
—
0
0
94
840
1.12
0.49
1.4
1.5
—
—
—
0
0
125
1137
1.10
0.48
1.5
1.9
—
—
—
0
0
58
503
1.16
0.47
1.4
1.4
2.26
3.94
ug/l
2.07
51
450
126
1150
1.10
0.46
1.5
1.9
—
—
—
0
0
125
1142
1.10
0.45
1.5
1.9
—
—
—
0
0
2154
21314
1.05
0.45
25.5
15.7
331.53
331.81
g/l
0.82
2144
21192
8
121
0.66
0.45
1.3
1.2
218.00
328.85
u/l
—
8
110
25
201
1.25
0.45
1.0
1.0
0.27
1.66
u/ml
—
9
57
120
1097
1.10
0.44
1.2
1.3
203.49
220.55
miu/ml
0.24
66
569
31
257
1.21
0.43
2.4
2.5
—
—
—
0
0
6
93
0.64
0.42
6.0
2.4
150.33
145.96
nmol/l
—
6
84
6
95
0.63
0.42
3.3
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
39.59
—
0
15
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
0.11
—
0
10
24
195
1.23
0.40
1.5
1.5
—
—
—
0
0
5
35
1.43
0.39
1.4
2.0
2.40
4.43
%
—
5
35
5
35
1.43
0.39
1.2
2.1
—
—
—
0
0
96
875
1.10
0.38
1.6
1.8
—
—
—
0
0
11
80
1.38
0.38
1.0
1.0
—
—
—
0
0
9
68
1.32
0.37
1.3
1.2
—
—
—
0
0
22
179
1.23
0.37
1.4
1.4
—
—
—
0
0
16
125
1.28
0.37
1.8
1.8
1.30
1.63
u/ml
—
5
39
73
804
0.91
0.34
1.9
2.6
—
—
—
0
0
12
155
0.77
0.33
1.0
1.2
—
—
—
0
0
75
683
1.10
0.32
1.1
1.1
2.73
1.96
u/ml
0.20
42
354
28
238
1.18
0.32
2.0
1.9
0.79
0.87
%
0.34
18
155
7
57
1.23
0.29
2.0
1.6
—
—
—
0
0
39
345
1.13
0.28
2.8
2.3
—
—
—
0
0
12
94
1.28
0.28
1.3
2.3
11.63
7.73
mmol/l
0.65
12
94
8
62
1.29
0.28
1.3
1.2
—
—
—
0
0
8
63
1.27
0.27
1.3
1.3
8.51
7.56
mmol/l
—
8
63
56
508
1.10
0.27
1.2
1.2
—
—
—
0
0
8
65
1.23
0.27
1.6
1.2
17.01
17.00
umol/l
—
8
54
53
481
1.10
0.26
1.1
1.1
0.52
4.12
u/ml
5.79
28
198
24
206
1.17
0.26
1.7
2.4
0.47
1.04
g/24h
1.81
11
118
5
72
0.69
0.26
1.2
1.0
60.42
30.24
iu/ml
—
5
72
20
169
1.18
0.25
1.3
1.6
1.05
1.27
promille
0.27
15
131
81
868
0.93
0.23
1.3
1.3
—
—
—
0
0
66
610
1.08
0.23
3.3
2.5
—
—
—
0
0
90
843
1.07
0.23
1.4
1.5
184.65
146.48
pmol/l
0.14
90
826
19
162
1.17
0.22
1.2
1.1
—
—
—
0
0
5
41
1.22
0.22
1.2
1.2
0.01
12.00
u/ml
—
5
41
13
107
1.22
0.21
4.0
2.7
19.16
19.38
ug/l
0.02
13
98
5
42
1.19
0.21
1.4
2.5
5.60
5.40
ug/l
—
5
42
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
1.4
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
0.01
—
0
5
30
268
1.12
0.20
1.3
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
0.06
—
0
8
6
53
1.13
0.18
1.0
1.2
—
—
—
0
0
64
599
1.07
0.18
1.9
1.4
0.45
0.42
nmol/l
0.14
51
475
7
60
1.17
0.17
1.0
1.3
—
—
—
0
0
26
233
1.12
0.17
1.2
1.3
—
—
—
0
0
55
513
1.07
0.17
1.0
1.1
1.16
4.02
u/ml
2.49
27
241
24
215
1.12
0.16
1.1
1.2
—
—
—
0
0
47
438
1.07
0.15
1.1
1.0
0.15
0.22
u/ml
0.29
22
123
7
89
0.79
0.14
1.6
1.5
0.59
0.50
e9/l
—
7
89
11
94
1.17
0.13
3.5
1.5
1.00
3.20
u/field
—
6
68
21
190
1.11
0.12
1.4
1.6
—
—
—
0
0
1073
10647
1.01
0.11
3.0
2.7
—
—
—
0
0
10
87
1.15
0.09
1.0
1.1
1982.00
636.24
ng/l
—
5
17
20
184
1.09
0.09
2.9
3.2
26.12
24.82
mu/l
0.08
20
178
34
360
0.94
0.09
1.1
1.1
—
—
—
0
0
16
175
0.91
0.08
2.6
2.1
—
—
—
0
0
30
283
1.06
0.08
2.6
2.6
—
28.81
—
0
20
8
77
1.04
0.07
3.3
1.6
—
—
—
0
0
46
479
0.96
0.07
1.9
2.4
—
—
—
0
0
9
88
1.02
0.07
2.7
3.5
—
—
—
0
0
15
140
1.07
0.04
1.1
1.1
—
—
—
0
0
26
271
0.96
0.04
1.1
1.1
—
—
—
0
0
15
144
1.04
0.00
1.3
1.2
—
—
—
0
0
19
194
0.98
0.00
1.0
1.0
0.11
0.25
u/ml
—
5
42
22
218
1.01
0.00
1.0
1.1
25.42
16.58
u/ml
0.57
12
105
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
77
0.91
-0.00
1.1
1.5
228.71
149.94
pmol/l
—
7
77
7
79
0.89
-0.00
1.9
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
98.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
3.00
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
34.54
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
44.12
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
258.13
—
0
8
0
7
0.00
-0.00
0.0
1.3
—
65.71
—
0
7
0
5
0.00
-0.00
0.0
7.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
220.57
—
0
7

Mortality – FinRegistry

Association

Association between endpoint AUTOIMMUNE_HYPERTHYROIDISM and mortality.

Females

Parameter HR [95% CI] p-value
AUTOIMMUNE_HYPERTHYROIDISM 1.083 [0.97, 1.21] 0.162
Birth year 0.998 [0.99, 1.01] 0.617

During the follow-up period (1.1.1998 — 31.12.2019), 1133 out of 10957 females with AUTOIMMUNE_HYPERTHYROIDISM died.

Males

Parameter HR [95% CI] p-value
AUTOIMMUNE_HYPERTHYROIDISM 1.223 [1.05, 1.42] 0.008
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 392 out of 2528 males with AUTOIMMUNE_HYPERTHYROIDISM died.

Mortality risk

Mortality risk for people of age

years, who have AUTOIMMUNE_HYPERTHYROIDISM.

N-year risk Females Males
1 0.117% 0.217%
5 0.744% 1.299%
10 1.652% 3.238%
15 3.454% 6.115%
20 6.064% 10.044%

Relationships between endpoints

Index endpoint: AUTOIMMUNE_HYPERTHYROIDISM – Autoimmune hyperthyroidism

GWS hits: 14

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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