No definition available.
Other congenital malformations of peripheral vascular system
EFO MESH Endpoint Browser PheWeb
Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
582 |
4. Check minimum number of eventsNone |
582 |
5. Include endpointsNone |
582 |
6. Filter based on genotype QC (FinnGen only) |
537 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_CIRCULATO_SYSTEM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q2
- Name in latin
- Aliae malformationes congenitae systematis vascularis peripherici
Similar endpoints
↥List of similar endpoints to
Other congenital malformations of peripheral vascular system
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of the circulatory system
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3588 | 2038 | 1530 |
| Only index persons | 3103 | 1810 | 1293 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.04 |
| Only index persons | 0.06 | 0.07 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 27.46 | 30.77 | 22.92 |
| Only index persons | 31.03 | 32.77 | 28.60 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 537 | 356 | 181 |
| Unadjusted period prevalence (%) | 0.11 | 0.13 | 0.08 |
| Median age at first event (years) | 46.06 | 42.90 | 52.29 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 556
- Matched controls
- 5560
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q27.3
ICD-10 Finland
Peripheral arteriovenous malformation
+∞
235.7
209
*
D18.0
ICD-10 Finland
Haemangioma, any site
34.0
210.0
141
55
Q27.4
ICD-10 Finland
Congenital phlebectasia
+∞
204.1
183
*
Q27.9
ICD-10 Finland
Congenital malformation of peripheral vascular system, unspecified
+∞
141.9
130
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
15.5
121.7
115
92
Q27.88
ICD-10 Finland
Other specified congenital malformation of peripheral vascular system
+∞
113.5
105
*
QX3LT
NOMESCO Finland
Subcutaneous sclerotherapy
656.1
61.0
59
*
XX6KT
NOMESCO Finland
Other sclerotherapy
226.7
41.5
42
*
D18.1
ICD-10 Finland
Lymphangioma, any site
346.7
33.3
33
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.9
28.2
171
728
Q27.0
ICD-10 Finland
Congenital absence and hypoplasia of umbilical artery
+∞
27.3
26
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.6
27.0
252
1333
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
10.5
26.7
30
30
Z2221
NOMESCO Finland
Medical doctor
2.7
26.5
211
1030
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
8.1
25.3
35
46
Q82.50
ICD-10 Finland
Naevus flammeus
130.6
23.8
25
*
EP1LT
NOMESCO Finland
Percutaneous sclerotherapy of vascular malformation of head and neck
+∞
23.1
22
*
PG1HT
NOMESCO Finland
Extensive endovascular embolisation of arterio-venous malformation not elsewhere classified
+∞
23.1
22
*
R4110
NOMESCO Finland
Physiotherapy
2.6
22.7
191
945
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
22.5
230
1245
XX4BW, ,
NOMESCO Finland
52.2
21.3
25
5
PG1JT
NOMESCO Finland
Very extensive endovascular embolisation of arterio-venous malformation not elsewhere classified
+∞
21.0
20
*
Q87.21
ICD-10 Finland
Klippel-Trénaunay-Weber syndrome
+∞
19.9
19
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
19.7
94
344
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.4
17.9
36
70
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
4.8
17.8
42
94
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
6.3
17.5
30
50
Z3226
NOMESCO Finland
Physiotherapist
2.6
17.5
127
578
JN5LT
NOMESCO Finland
Sclerotherapy with direct puncture body area
+∞
16.7
16
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.8
16.6
38
83
2280A
ICD-9 Finland
Haemangioma and lymphangioma, any site, Haemangioma, any site
175.0
16.6
17
*
22700
ICD-8 Finland
Haemangioma and lymphangioma, Haemangioma
87.6
15.6
17
*
ZXE00
NOMESCO Finland
One hour or less
2.1
15.4
245
1531
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
15.3
166
895
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
24.2
15.2
21
9
ZXC12
NOMESCO Finland
Pulse colorlaser
46.4
15.1
18
*
PG1GT
NOMESCO Finland
Endovascular embolisation of arterio-venous malformation with radiological guidance not elsewhere classified
+∞
14.6
14
*
Z31.5
ICD-10 Finland
Genetic counselling
3.2
14.6
61
205
ZXA05
NOMESCO Finland
Left side
2.3
14.5
129
639
R22.3
ICD-10 Finland
Localized swelling, mass and lump, upper limb
6.0
14.1
25
43
Q27.2
ICD-10 Finland
Other congenital malformations of renal artery
+∞
13.6
13
*
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
51.3
12.9
15
*
WX402
NOMESCO Finland
General anaesthesia
2.1
12.7
152
844
QX3KT, ,
NOMESCO Finland
+∞
11.5
11
*
Q27.1
ICD-10 Finland
Congenital renal artery stenosis
+∞
11.5
11
*
ZXA00
NOMESCO Finland
Right side
2.1
11.3
134
738
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
11.2
91
430
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
14.3
11.0
18
13
Z3231
NOMESCO Finland
Registered nurse
1.9
10.7
166
1003
I78.0
ICD-10 Finland
Hereditary haemorrhagic telangiectasia
61.2
10.7
12
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.2
10.5
43
143
PB1AC
NOMESCO Finland
Angiography of upper extremity with X-ray
112.1
10.5
11
*
I77.0
ICD-10 Finland
Arteriovenous fistula, acquired
112.1
10.5
11
*
Q27.80
ICD-10 Finland
Congenital stricture, artery
+∞
10.4
10
*
Q28.8
ICD-10 Finland
Other specified congenital malformations of circulatory system
+∞
10.4
10
*
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
+∞
10.4
10
*
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
4.1
10.2
28
71
Q82.58
ICD-10 Finland
Congenital non-neoplastic naevus
10.3
10.1
19
19
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
4.7
9.9
23
51
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
7.6
9.8
22
30
ZZA00
NOMESCO Finland
Split skin graft
5.4
9.7
19
36
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
4.9
9.6
21
44
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
15.4
9.6
15
10
PG1CG
NOMESCO Finland
Extensive MRI examination of vasculature with high intensity magnet not elsewhere classified
101.7
9.4
10
*
QD9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in lower extremities, unspecified
30.6
9.4
12
*
Q28.3
ICD-10 Finland
Other malformations of cerebral vessels
+∞
9.4
9
*
PA5AC
NOMESCO Finland
Angiography of arteries to the face with X-ray
+∞
9.4
9
*
I87.8
ICD-10 Finland
Other specified disorders of veins
+∞
9.4
9
*
PG1DG
NOMESCO Finland
Very extensive MRI examination of vasculature with high intensity magnet not elsewhere classified
+∞
9.4
9
*
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
22.1
9.4
13
6
WX002
NOMESCO Finland
Sedation and analgesia
2.1
9.3
98
513
ZXD20
NOMESCO Finland
Day surgery
2.3
9.2
77
368
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
9.0
81
399
ZXA10
NOMESCO Finland
Bilateral
2.1
8.9
99
528
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.7
8.7
49
195
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
8.4
8.6
18
22
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.2
8.5
33
106
Q28.2
ICD-10 Finland
Arteriovenous malformation of cerebral vessels
+∞
8.4
8
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.8
8.3
43
163
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
4.5
8.0
19
43
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
7.8
61
282
A46
ICD-10 Finland
Erysipelas
2.2
7.8
70
344
I87.9
ICD-10 Finland
Disorder of vein, unspecified
15.3
7.7
12
8
R4120
NOMESCO Finland
Occupational therapy
2.5
7.4
45
186
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
11.1
7.3
13
12
Q21.10
ICD-10 Finland
Persistent ostium secundum
+∞
7.3
7
*
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
+∞
7.3
7
*
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.2
7.3
63
305
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.3
7.2
27
85
H02AB06
ATC
prednisolone; systemic
1.6
7.2
235
1721
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
8.1
7.1
15
19
N03AX16
ATC
[U] pregabalin
1.8
7.1
111
662
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.0
7.1
78
414
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.7
6.9
22
62
QX3HE, ,
SPAT
3.5
6.9
23
67
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
16.9
6.8
10
6
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.9
6.6
19
50
Z2446
NOMESCO Finland
Social worker
2.3
6.6
50
229
PHT99
NOMESCO Finland
Injection of therapeutic or sclerosing agent into other vein
10.2
6.6
12
12
TQW40
NOMESCO Finland
Remowal of suture of skin
2.5
6.5
41
173
XF600
NOMESCO Finland
Bloodpressure measurement
2.5
6.3
39
162
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.1
6.3
58
287
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
9.4
6.3
12
13
Z71.8
ICD-10 Finland
Other specified counselling
1.6
6.3
208
1516
I15.0
ICD-10 Finland
Renovascular hypertension
18.3
6.3
9
5
I77.9
ICD-10 Finland
Disorder of arteries and arterioles, unspecified
+∞
6.3
6
*
Q28.9
ICD-10 Finland
Congenital malformation of circulatory system, unspecified
+∞
6.3
6
*
Q25.0
ICD-10 Finland
Patent ductus arteriosus
+∞
6.3
6
*
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
+∞
6.3
6
*
FM2CE, ,
NOMESCO Finland
7.2
6.3
14
20
WX203
NOMESCO Finland
Infraclavicular plexus blockade
3.7
6.2
19
52
Q82.51
ICD-10 Finland
Naevus portwine
27.0
6.2
8
*
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
6.4
6.2
15
24
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
6.1
231
1736
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
244
1143
3.02
34.97
6.1
4.5
91.85
93.62
%
0.55
239
1120
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
30
28
11.27
27.99
1.3
1.0
101.83
122.18
%
1.06
30
28
29
28
10.87
26.43
1.1
1.0
96.33
95.23
%
0.05
12
13
28
29
10.11
24.29
1.1
1.0
87.18
101.07
%
0.79
11
14
207
1128
2.33
19.31
2.9
2.3
—
—
—
0
0
41
85
5.13
19.02
1.2
1.2
—
—
—
0
0
42
89
5.02
19.01
1.3
1.2
2.00
2.33
u/ml
0.15
14
36
42
89
5.02
19.01
1.3
1.2
2.52
3.13
u/ml
0.31
27
38
199
1086
2.30
18.32
3.5
2.0
1.06
1.00
mg/l
0.12
159
835
272
1754
2.08
15.81
12.6
9.6
1.15
1.14
inr
0.19
225
1465
307
2208
1.87
11.71
3.4
2.8
—
—
estimate
—
0
0
308
2282
1.78
10.05
11.7
10.8
0.00
0.00
e9/l
0.59
241
1846
122
693
1.97
9.26
4.0
2.6
2.46
2.39
g/l
0.81
114
641
113
632
1.99
8.94
4.3
2.7
21.83
23.80
%
0.90
106
596
261
1906
1.70
8.45
10.8
7.8
1.21
1.22
mmol/l
0.74
240
1782
125
745
1.87
8.13
4.1
2.6
13.50
14.02
umol/l
0.34
120
693
284
2136
1.67
8.12
9.4
8.1
1.21
1.22
mmol/l
0.38
248
1884
354
2826
1.70
8.01
10.4
10.0
3.69
3.97
e9/l
1.63
300
2455
19
29
6.74
7.95
1.0
1.1
—
—
—
0
0
527
4803
2.86
7.61
17.2
13.2
23.26
21.29
mg/l
0.58
439
3822
31
109
2.95
6.90
1.5
1.3
—
—
—
0
0
115
709
1.78
6.60
3.0
3.2
2.70
2.68
e6/l
0.01
45
327
174
1206
1.64
6.50
4.0
2.3
2.82
2.69
mg/l
0.18
157
1047
118
757
1.71
5.85
2.9
3.0
0.47
0.82
e6/l
1.31
51
373
512
4700
2.13
5.63
19.8
14.6
139.89
139.65
mmol/l
2.15
503
4612
242
1863
1.53
5.57
6.8
5.3
37.00
36.92
g/l
0.08
232
1774
77
442
1.86
5.54
4.7
7.4
1.28
1.48
mmol/l
0.18
66
374
512
4706
2.11
5.51
19.9
14.7
3.92
3.94
mmol/l
1.12
501
4600
401
3460
1.57
5.30
9.0
7.6
78.65
80.23
u/l
0.23
383
3297
172
1248
1.55
5.10
3.2
3.2
0.46
0.35
e6/l
0.22
111
879
199
1495
1.52
5.01
3.8
3.1
2.36
2.36
mmol/l
0.02
182
1378
550
5305
4.41
4.89
26.6
20.2
254.54
258.95
e9/l
0.84
542
5215
550
5310
4.32
4.75
26.6
20.2
4.49
4.54
e12/l
1.90
540
5209
317
2636
1.47
4.72
7.9
5.6
6.24
6.41
mmol/l
0.87
298
2457
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
25
97
2.65
4.70
6.9
4.4
0.27
0.36
iu/ml
1.04
12
53
27
109
2.55
4.70
2.0
2.6
0.00
0.00
g/l
-0.00
22
98
191
1446
1.49
4.55
3.5
3.3
14.42
93.39
e6/l
1.05
130
1081
57
321
1.86
4.36
4.0
2.4
74.75
72.13
ml/min/173m2
0.18
20
139
59
343
1.81
4.09
2.7
3.6
4.61
4.67
pmol/l
0.23
53
307
84
540
1.65
4.08
13.9
9.1
104.88
104.32
mmol/l
0.50
84
540
214
1696
1.43
3.89
4.0
3.4
26.49
30.71
u/l
2.12
208
1616
112
785
1.53
3.78
2.9
2.3
2.42
2.43
mmol/l
0.57
97
698
281
2345
1.40
3.76
7.8
6.5
11.96
11.31
umol/l
0.28
266
2227
67
417
1.69
3.68
3.2
2.6
—
—
—
0
0
431
3887
1.48
3.68
4.7
4.4
14.58
14.49
pmol/l
0.33
405
3623
42
228
1.91
3.62
1.2
1.4
—
—
—
0
0
143
1071
1.45
3.47
3.1
3.0
329.77
329.16
umol/l
0.02
126
973
90
612
1.56
3.47
8.6
7.7
1.10
1.10
mmol/l
0.04
84
573
26
121
2.21
3.37
2.1
2.3
961.50
290.52
ug/l
0.81
26
113
10
23
4.41
3.32
1.2
1.1
—
—
—
0
0
84
572
1.55
3.22
4.6
3.3
5.20
7.99
umol/l
1.94
72
490
100
709
1.50
3.18
4.8
4.5
0.81
0.82
mmol/l
0.23
93
679
107
772
1.48
3.13
4.4
3.3
118.88
397.96
ng/l
1.36
75
496
28
139
2.07
3.11
1.3
1.6
185.00
145.09
au/ml
—
10
42
10
25
4.05
3.10
2.0
3.3
0.70
0.96
index
—
10
25
471
4379
1.49
2.94
16.0
11.8
91.08
89.70
ml/min/173m2
0.66
427
3927
32
172
1.91
2.88
2.0
1.8
40.41
37.66
nmol/l
0.23
32
167
303
2636
1.33
2.78
4.6
3.3
89.43
86.87
ug/l
0.09
283
2499
13
48
2.75
2.73
1.2
1.3
—
—
—
0
0
38
220
1.78
2.72
8.9
7.3
24.51
24.31
mmol/l
0.26
38
215
29
154
1.93
2.71
1.2
1.5
203.00
215.59
u/ml
0.14
19
85
5
7
7.20
2.55
1.0
1.9
—
—
—
0
0
67
460
1.52
2.49
2.6
2.6
26.28
30.97
u/l
1.23
58
383
215
1804
1.31
2.47
2.1
2.0
93.03
97.47
pmol/l
0.80
116
953
13
51
2.59
2.46
1.2
1.2
—
—
—
0
0
13
51
2.59
2.46
1.2
1.3
—
—
—
0
0
13
51
2.59
2.46
1.2
1.2
—
—
—
0
0
388
3531
1.33
2.42
4.9
4.1
9.82
9.87
mm/h
0.02
366
3315
10
33
3.07
2.36
2.2
3.3
13.40
13.44
index
—
10
25
26
140
1.90
2.36
1.3
1.3
9.00
58.63
u/ml
—
5
13
478
4505
1.44
2.30
5.8
5.3
1.81
1.84
mu/l
0.21
452
4273
154
1247
1.32
2.25
2.5
2.1
202.04
245.37
u/l
0.29
147
1190
8
24
3.37
2.18
1.9
1.4
5.38
6.47
mmol/l
—
8
24
13
55
2.40
2.13
1.2
1.2
—
—
—
0
0
11
43
2.59
2.09
2.4
1.8
—
—
—
0
0
46
305
1.55
2.03
7.9
6.3
0.93
1.12
mmol/l
0.17
37
227
248
2162
1.27
2.01
3.2
2.7
74.59
73.46
nmol/l
0.29
235
1998
29
171
1.73
2.01
1.3
1.3
2.52
5.94
u/ml
—
6
28
520
5008
1.59
1.98
12.8
10.6
24.92
26.05
u/l
1.19
508
4897
20
105
1.94
1.98
4.2
2.1
—
—
—
0
0
10
39
2.59
1.95
1.1
1.2
107.70
113.87
pmol/l
—
10
39
8
27
2.99
1.94
1.1
1.1
—
—
—
0
0
11
45
2.47
1.94
1.2
1.6
1.71
1.29
promille
—
6
36
121
967
1.32
1.92
2.6
2.6
6.88
7.20
e6/l
0.08
113
884
20
107
1.90
1.88
1.1
1.1
6.74
2.03
eliau/ml
—
7
45
377
3469
1.27
1.87
3.9
3.4
37.05
40.36
u/l
0.46
360
3331
9
35
2.60
1.81
2.2
1.7
—
—
—
0
0
121
978
1.30
1.77
3.7
3.3
1126.57
913.63
ng/l
0.38
92
805
16
81
2.00
1.76
1.4
1.3
—
—
—
0
0
16
81
2.00
1.76
1.4
1.3
—
—
—
0
0
8
30
2.69
1.73
1.0
1.1
1938.13
1557.67
miu/ml
—
8
30
13
61
2.16
1.72
1.2
1.3
—
—
—
0
0
5
13
3.87
1.72
1.6
1.6
45.44
44.40
g/l
—
5
13
12
56
2.17
1.62
1.2
1.3
—
90.00
—
0
6
34
225
1.54
1.55
4.2
7.4
0.59
0.60
%
0.03
34
225
24
146
1.67
1.53
1.3
1.1
—
—
—
0
0
286
2586
1.22
1.53
3.5
3.7
0.00
0.01
estimate
0.80
43
503
41
285
1.47
1.50
2.0
1.8
—
—
—
0
0
27
171
1.61
1.49
2.5
1.9
1.81
3.93
iu/l
—
9
70
32
212
1.54
1.47
1.4
1.6
—
—
—
0
0
24
148
1.65
1.46
1.3
1.1
—
—
—
0
0
5
16
3.14
1.44
1.6
1.3
—
—
—
0
0
19
111
1.74
1.41
1.3
1.4
—
—
—
0
0
54
403
1.38
1.36
1.3
1.5
23.89
21.61
iu/l
0.20
43
334
55
412
1.37
1.36
21.3
10.2
0.87
0.78
mmol/l
0.05
49
350
5
17
2.96
1.36
2.0
1.2
—
—
—
0
0
72
564
1.32
1.34
1.9
1.7
1187.48
1172.33
nmol/l
0.05
51
442
279
2539
1.20
1.33
3.5
3.6
0.00
0.00
estimate
0.50
45
531
452
4312
1.26
1.31
3.7
3.8
1.22
1.26
mmol/l
0.59
427
4073
61
471
1.33
1.26
1.9
1.9
—
—
—
0
0
398
3754
1.21
1.25
3.5
3.6
—
—
—
0
0
8
36
2.24
1.24
1.1
1.2
—
—
—
0
0
22
140
1.59
1.22
1.2
1.3
—
—
—
0
0
47
353
1.36
1.17
1.5
1.5
—
—
—
0
0
18
110
1.66
1.16
1.2
1.5
—
—
—
0
0
14
80
1.77
1.14
2.6
1.7
—
—
—
0
0
47
355
1.35
1.13
19.6
10.6
121.85
121.28
g/l
0.06
47
348
87
717
1.25
1.11
1.7
1.8
1.35
1.40
%
0.36
77
648
20
128
1.58
1.10
2.0
1.6
—
—
—
0
0
172
1521
1.19
1.10
3.1
3.2
46.33
77.38
ng/l
0.28
106
907
61
483
1.30
1.07
2.0
1.8
—
—
—
0
0
278
2566
1.17
1.04
3.6
3.6
0.00
8.47
estimate
1.08
46
536
5
22
2.28
1.03
1.0
1.6
—
—
—
0
0
5
22
2.28
1.03
1.0
1.6
—
—
—
0
0
5
22
2.28
1.03
1.0
1.6
—
—
—
0
0
5
22
2.28
1.03
5.6
2.9
65.40
121.54
ug/l
—
5
22
5
22
2.28
1.03
1.0
1.6
—
—
—
0
0
134
1166
1.20
1.02
1.8
1.6
21.20
20.60
nmol/l
0.17
122
1014
31
223
1.41
1.01
1.7
1.7
—
—
—
0
0
58
461
1.29
1.00
1.2
1.3
90.37
164.54
u/ml
1.07
13
191
14
84
1.68
0.98
1.3
1.2
—
—
—
0
0
472
4561
1.23
0.98
4.7
4.5
4.68
4.69
mmol/l
0.05
446
4353
114
981
1.20
0.98
1.3
1.3
15.92
27.57
iu/ml
1.95
30
283
470
4541
1.23
0.97
4.6
4.4
1.47
1.47
mmol/l
0.01
444
4312
10
54
1.87
0.97
1.0
1.1
—
—
—
0
0
16
102
1.59
0.91
3.9
2.7
—
—
—
0
0
33
246
1.36
0.89
1.5
1.5
—
—
—
0
0
8
42
1.92
0.89
1.1
1.1
—
—
—
0
0
33
247
1.36
0.87
4.4
7.4
128.88
130.44
g/l
0.14
33
240
6
30
2.01
0.87
3.2
4.2
385.00
1131.37
mg
—
6
30
11
64
1.73
0.86
1.7
1.4
—
—
—
0
0
35
266
1.34
0.85
1.5
1.6
75.21
62.25
ug/l
0.45
27
225
6
31
1.95
0.84
1.2
3.1
532.17
711.74
u/ml
—
6
31
10
57
1.77
0.84
2.3
1.5
—
—
—
0
0
34
258
1.34
0.83
2.9
1.6
0.39
0.31
mg/l
0.23
14
117
35
267
1.33
0.83
1.7
2.2
2.64
6.26
ug/l
3.05
27
240
11
65
1.71
0.83
2.6
1.5
—
—
—
0
0
32
242
1.34
0.81
1.6
2.1
4.15
4.71
iu/ml
—
6
49
437
4215
1.17
0.81
5.1
5.4
37.03
38.06
mmol/mol
2.20
415
4030
473
4593
1.20
0.80
5.1
5.0
2.82
2.79
mmol/l
0.29
447
4369
65
541
1.23
0.79
2.3
3.0
0.67
0.74
ug/l
0.41
33
324
0
24
0.00
0.79
0.0
3.1
—
1.38
—
0
24
41
323
1.29
0.79
1.7
1.4
—
—
—
0
0
33
252
1.33
0.78
1.5
1.5
1.06
1.22
ratio
0.61
21
161
33
252
1.33
0.78
1.5
1.5
1.51
1.22
ratio
0.35
21
161
33
252
1.33
0.78
1.5
1.5
0.87
0.94
ratio
0.94
21
161
78
664
1.20
0.77
2.1
1.9
—
—
—
0
0
15
99
1.53
0.76
7.1
4.1
36.00
36.32
umol/l
0.02
15
93
214
1976
1.13
0.74
2.3
1.9
1.27
1.38
mmol/l
1.67
185
1721
7
38
1.85
0.73
1.0
1.7
—
—
—
0
0
7
38
1.85
0.73
1.0
1.7
—
—
—
0
0
7
38
1.85
0.73
1.0
1.7
—
—
—
0
0
18
125
1.45
0.73
1.5
1.2
—
—
—
0
0
5
25
2.01
0.73
1.0
1.0
—
—
—
0
0
10
60
1.68
0.72
1.0
1.1
—
—
—
0
0
10
60
1.68
0.72
1.6
1.3
—
—
—
0
0
10
60
1.68
0.72
1.8
1.3
363.50
516.22
pmol/l
—
10
54
7
41
1.72
0.70
2.0
1.5
—
—
—
0
0
11
69
1.61
0.69
1.4
1.3
—
—
—
0
0
5
27
1.86
0.68
2.0
1.9
0.12
0.14
nmol/l
—
5
22
5
27
1.86
0.68
2.4
1.4
—
—
—
0
0
157
1428
1.14
0.68
2.4
2.7
54.35
59.48
u/l
0.60
137
1341
450
4370
1.16
0.66
4.2
4.3
5.70
5.75
mmol/l
0.34
423
4092
5
28
1.79
0.66
2.2
1.4
—
—
—
0
0
10
62
1.62
0.65
1.0
1.1
—
—
—
0
0
51
425
1.22
0.64
6.5
6.2
—
—
—
0
0
13
188
0.68
0.63
2.0
1.8
—
—
—
0
0
12
176
0.67
0.63
7.2
4.3
24.10
24.73
mmol/l
0.27
12
170
8
49
1.64
0.62
2.8
2.0
—
—
—
0
0
18
130
1.40
0.62
2.9
2.3
11.01
10.63
mg/l
0.08
18
120
102
908
1.15
0.61
4.2
4.6
1.56
2.15
ug/l
0.93
88
829
0
20
0.00
0.60
0.0
1.2
—
8.24
—
0
20
50
420
1.21
0.59
1.2
1.3
67.03
304.01
u/ml
2.75
44
389
18
132
1.38
0.57
2.5
1.7
—
—
—
0
0
11
73
1.52
0.56
2.3
1.4
—
—
—
0
0
11
73
1.52
0.56
1.6
1.5
—
—
—
0
0
24
186
1.30
0.55
1.3
1.3
—
—
—
0
0
37
304
1.23
0.54
3.5
3.7
1.23
1.22
mmol/l
0.82
30
260
78
688
1.16
0.54
1.8
1.9
3.52
3.49
ratio
0.07
62
533
10
66
1.52
0.53
2.7
2.9
2.66
11.37
u/ml
—
10
66
11
157
0.69
0.52
6.1
7.1
1.28
1.58
%
0.41
11
146
162
1505
1.11
0.49
4.3
3.4
8.30
8.17
mmol/l
0.11
140
1310
16
119
1.35
0.48
2.0
1.5
—
—
—
0
0
10
68
1.48
0.47
1.8
1.5
8.32
7.15
mmol/l
—
10
59
13
94
1.39
0.46
2.1
1.5
—
—
—
0
0
5
81
0.61
0.46
8.0
6.3
375.40
370.88
umol/l
—
5
75
43
367
1.19
0.45
2.7
2.4
34.69
16.95
au/ml
—
7
32
184
1951
0.91
0.43
3.4
3.4
0.00
0.02
estimate
1.39
31
456
5
31
1.62
0.43
1.2
1.8
2.50
3.33
mg/l
—
5
31
5
32
1.57
0.42
1.2
1.2
—
—
—
0
0
10
70
1.44
0.42
3.5
1.5
—
—
—
0
0
13
96
1.36
0.42
1.5
1.5
—
—
—
0
0
80
722
1.13
0.41
2.8
4.1
23.39
22.22
%
0.21
28
320
18
227
0.79
0.41
1.3
1.7
—
—
—
0
0
17
132
1.30
0.40
1.9
1.3
258.67
305.99
ug/g
—
9
73
0
18
0.00
0.40
0.0
1.1
—
71.17
—
0
18
11
147
0.74
0.37
2.0
1.7
—
—
—
0
0
8
112
0.71
0.37
1.0
2.3
1.43
0.80
nmol/l
—
8
95
13
169
0.76
0.37
1.3
1.6
54.40
52.95
ug/l
0.06
13
169
108
1164
0.91
0.36
3.7
3.5
1.02
1.02
kg/l
0.52
68
757
5
77
0.65
0.36
1.2
1.4
—
234.29
—
0
7
42
367
1.16
0.35
1.0
1.0
—
—
—
0
0
115
1070
1.09
0.35
2.4
2.3
—
—
—
0
0
20
163
1.24
0.34
1.1
1.1
1.74
5.74
u/ml
2.10
13
103
6
44
1.37
0.34
1.5
1.2
43.13
37.18
nmol/l
—
6
34
18
221
0.81
0.34
13.3
8.6
26.80
24.51
mmol/l
0.84
18
210
20
240
0.83
0.31
1.8
1.8
2.51
3.55
mg/l
0.56
15
178
15
120
1.26
0.30
1.0
1.1
0.00
0.42
u/ml
—
9
44
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
8
62
1.29
0.28
2.9
1.8
—
—
—
0
0
14
113
1.25
0.27
1.1
1.2
—
—
—
0
0
44
485
0.90
0.24
4.9
4.1
33.64
31.84
%
0.50
33
349
10
78
1.29
0.24
1.7
1.5
—
—
—
0
0
144
1506
0.94
0.24
1.4
1.5
1.13
1.86
u/ml
0.71
37
402
10
79
1.27
0.22
1.6
1.1
—
—
—
0
0
143
1369
1.06
0.22
3.9
3.6
0.00
0.01
estimate
1.08
44
509
0
11
0.00
0.21
0.0
1.3
—
402.00
—
0
6
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.05
—
0
7
0
12
0.00
0.21
0.0
1.0
—
2.24
—
0
7
0
13
0.00
0.21
0.0
1.0
—
0.01
—
0
8
0
13
0.00
0.21
0.0
2.2
—
1.22
—
0
13
0
14
0.00
0.20
0.0
1.2
—
0.22
—
0
14
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
38
346
1.11
0.20
3.0
4.2
3.10
21.74
ug/l
0.85
26
279
6
50
1.20
0.19
4.3
4.3
—
—
—
0
0
141
1466
0.95
0.19
2.9
3.0
0.00
0.02
estimate
1.35
32
443
13
154
0.84
0.19
2.1
1.9
—
—
—
0
0
130
1249
1.05
0.18
5.3
4.2
6.24
10.27
mg/mmol
1.06
89
797
57
534
1.08
0.17
2.4
2.1
393.20
381.29
nmol/l
0.18
50
507
22
246
0.89
0.16
1.2
1.2
0.90
0.91
g/l
0.07
22
246
103
988
1.05
0.15
2.2
2.2
—
—
—
0
0
95
910
1.05
0.15
1.3
1.3
12.20
8.97
u/ml
0.19
41
358
15
131
1.15
0.14
1.3
2.1
29.20
14.15
e6/l
—
10
97
15
132
1.14
0.13
1.3
2.2
1.40
254.00
e6/l
—
10
102
23
252
0.91
0.13
1.6
1.6
7.18
8.83
u/l
0.43
17
194
88
849
1.04
0.11
1.8
1.6
442.16
35887527.42
pmol/l
1.04
70
744
22
239
0.92
0.10
1.2
1.1
1.55
1.55
g/l
0.01
22
239
40
378
1.06
0.10
2.1
2.2
217.67
4647.06
u/l
3.45
11
157
103
1000
1.04
0.10
1.5
1.6
—
—
—
0
0
29
310
0.93
0.10
1.5
1.5
—
—
—
0
0
22
203
1.09
0.09
1.8
1.7
6.58
6.91
u/ml
—
6
58
6
70
0.86
0.07
1.0
1.1
—
—
—
0
0
24
225
1.07
0.07
1.5
1.4
—
—
—
0
0
55
531
1.04
0.07
1.4
1.7
3.31
3.46
mmol/l
0.39
39
376
13
119
1.09
0.06
2.2
1.6
—
—
—
0
0
13
140
0.93
0.04
1.2
1.3
—
—
—
0
0
146
1444
1.02
0.03
1.7
1.8
—
—
—
0
0
21
220
0.95
0.03
1.2
1.4
—
—
—
0
0
18
188
0.96
0.02
1.1
1.2
0.84
2.86
u/ml
1.50
12
112
46
468
0.98
0.01
1.5
1.6
1200.14
942.25
mu/l
0.57
36
399
21
214
0.98
0.00
1.8
1.6
—
—
—
0
0
12
117
1.03
0.00
2.3
1.9
—
—
—
0
0
69
686
1.01
0.00
2.5
2.1
—
—
—
0
0
16
162
0.99
0.00
1.1
1.1
0.40
1.69
u/ml
1.86
11
92
27
271
1.00
0.00
1.1
1.4
249.17
256.78
miu/ml
0.03
11
140
58
581
1.00
0.00
2.4
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
7
74
0.95
-0.00
3.6
2.9
17.71
27.57
u/ml
—
7
74
5
58
0.86
-0.00
1.2
1.4
—
—
—
0
0
8
85
0.94
-0.00
2.0
3.2
6.29
8.06
pmol/l
—
8
85
5
59
0.85
-0.00
1.2
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
1.19
—
0
9
0
5
0.00
-0.00
0.0
1.6
—
6.10
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
1.08
—
0
5
5
57
0.88
-0.00
6.4
3.6
143.20
215.02
e6/l
—
5
42
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.6
—
—
—
0
0
5
57
0.88
-0.00
1.2
1.4
—
—
—
0
0
5
59
0.85
-0.00
1.2
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
-0.00
1.2
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
-0.00
1.2
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM | 1.126 [0.85, 1.5] | 0.416 |
| Birth year | 0.994 [0.99, 1.0] | 0.189 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 1690 females with Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM | 1.198 [0.87, 1.65] | 0.266 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 1287 males with Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM died.
Mortality risk
Mortality risk for people of age
years, who have Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.135% | 0.224% |
| 5 | 0.647% | 1.384% |
| 10 | 1.645% | 3.654% |
| 15 | 3.268% | 6.451% |
| 20 | 5.809% | 10.974% |
Relationships between endpoints
↥Index endpoint: Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM – Other congenital malformations of peripheral vascular system
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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