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Endocrine disorders, other/unspecified

DOID EFO Endpoint Browser PheWeb

E4_ENDODISNAS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E34.8, E34.9
  • Hospital discharge: ICD-9 — 2592
  • Hospital discharge: ICD-8 — 2589
  • Cause of death: ICD-10 — E34.8, E34.9
  • Cause of death: ICD-9 — 2592
  • Cause of death: ICD-8 — 2589

2 out of 7 registries used, show all original rules.

804

4. Check minimum number of events

None

804

5. Include endpoints

None

804

6. Filter based on genotype QC (FinnGen only)

731

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4629 2915 1690
Only index persons 4059 2629 1430
Unadjusted period prevalence (%)
Whole population 0.07 0.08 0.05
Only index persons 0.08 0.10 0.05
Median age at first event (years)
Whole population 45.31 43.58 47.96
Only index persons 42.47 41.28 44.67

-FinnGen-

Key figures

All Female Male
Number of individuals 731 491 240
Unadjusted period prevalence (%) 0.15 0.17 0.11
Median age at first event (years) 44.00 40.67 50.81

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
752
Matched controls
7520
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
+∞
307.7
592
*
H02AB09
ATC
hydrocortisone; systemic
25.2
137.0
99
45
ZXE00
NOMESCO Finland
One hour or less
4.0
76.9
457
2089
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
8.7
70.4
95
123
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
124.4
64.0
68
6
H03AA01
ATC
levothyroxine sodium; systemic
3.7
64.0
308
1192
25898
ICD-8 Finland
Polyglandular dysfunction and other diseases of endocrine glands, Alii definiti
+∞
62.4
59
*
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
90.4
60.0
66
8
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
5.7
58.5
120
241
SPAT1262
SPAT
Handing over of treatment supplies
3.9
57.9
217
704
WX723
NOMESCO Finland
CPAP therapy
6.7
55.6
94
156
ZXE10
NOMESCO Finland
More than one and less than three hours
3.2
52.8
379
1826
XX3DW
NOMESCO Finland
Time consuming IT work
4.2
51.9
162
458
25899
ICD-8 Finland
Polyglandular dysfunction and other diseases of endocrine glands, Other and unspecified diseases of endocrine system
+∞
51.7
49
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.4
50.3
108
225
E34.8
ICD-10 Finland
Other specified endocrine disorders
+∞
49.5
47
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
5.1
49.0
115
259
SPAT1312
SPAT
General health counselling
3.0
47.0
340
1619
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.9
46.9
168
522
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
44.2
42
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.1
43.6
260
1104
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
6.0
42.8
80
146
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
+∞
42.1
40
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.8
41.2
390
2104
SPAT1377
SPAT
Polysomnography
7.0
41.0
65
100
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
13.7
40.2
38
29
WX780
NOMESCO Finland
Remote monitoring CPAP
5.5
40.0
82
163
NH3EA
NOMESCO Finland
Feet X-ray examination with load
8.4
39.7
53
67
SPAT1249
SPAT
Treatment-related counselling outside office
2.6
35.8
377
2101
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.2
35.4
172
640
SPAT1263
SPAT
Sampling
2.6
34.7
391
2241
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
34.6
33
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.6
33.7
284
1414
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
32.8
424
2566
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
12.3
32.7
33
28
OAB50, ,
SPAT
3.8
32.7
112
333
A11CC03
ATC
alfacalcidol; systemic
9.0
32.5
41
48
XFE00
NOMESCO Finland
Epicardial ultrasonography
9.9
31.7
37
39
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
12.4
30.9
31
26
ZXD00
NOMESCO Finland
Emergency procedure
6.2
30.8
54
92
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.5
30.2
276
1414
JN3AD
NOMESCO Finland
Abdominal CT examination
3.1
30.1
149
557
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
29.2
144
536
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
29.2
248
1225
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
7.9
28.7
40
53
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
6.2
28.2
50
86
G02CB01
ATC
bromocriptine; systemic
8.0
27.4
38
50
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
+∞
27.2
26
*
Z01.9
ICD-10 Finland
Special examination, unspecified
3.8
27.1
88
251
XX2RW, ,
NOMESCO Finland
9.3
27.0
33
37
J01MA12
ATC
levofloxacin; systemic
2.7
26.6
176
766
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.3
26.5
113
385
UJF32
NOMESCO Finland
Coloscopy
2.4
26.2
241
1225
WZC00
NOMESCO Finland
Treatment plan or consultation
2.3
26.2
339
1995
H01CB02
ATC
octreotide; parenteral
96.9
25.8
28
*
E22.1
ICD-10 Finland
Hyperprolactinaemia
139.8
25.8
27
*
HAHOM, ,
NOMESCO Finland
10.4
25.7
29
29
E34.0
ICD-10 Finland
Carcinoid syndrome
+∞
25.1
24
*
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
9.4
24.9
30
33
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
258.3
24.8
25
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
5.3
24.5
51
102
104
Kela drug reimbursment
Thyroid insufficiency
3.5
24.4
89
274
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
24.1
23
*
106
Kela drug reimbursment
Hypoparathyroidism
+∞
24.1
23
*
SPAT1310
SPAT
Counselling related to known health issue
2.2
24.1
287
1619
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
3.0
23.5
116
430
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
4.3
22.8
62
155
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
8.0
22.7
31
40
WX402
NOMESCO Finland
General anaesthesia
2.3
22.7
214
1090
121
Kela drug reimbursment
Severe hypofunction of sexual glands
7.2
22.6
34
49
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.7
22.4
74
213
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.3
22.2
217
1121
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
5.3
22.1
46
92
A02BC01
ATC
omeprazole; systemic
2.2
21.8
245
1339
SPAT1281
SPAT
Other administrative function
3.2
21.3
90
304
G47.3
ICD-10 Finland
Sleep apnoea
2.3
21.0
209
1084
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
61.9
21.0
24
*
H01AC01
ATC
somatropin; parenteral
+∞
20.9
20
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
20.7
286
1688
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.9
20.6
106
401
SPAT1301
SPAT
No procedures
2.1
20.6
268
1547
WVA30, ,
SPAT
3.5
20.5
76
236
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.9
20.1
103
388
-44
ICPC
Preventive immunization/medic
3.2
19.9
86
294
SPAT1153
SPAT
Removal of sutures
2.1
19.5
265
1549
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.8
19.2
60
166
C03CA01
ATC
furosemide; systemic
2.2
19.1
221
1212
N06AA09
ATC
amitriptyline; systemic
2.9
19.1
100
381
UDC00
NOMESCO Finland
Ear microscopy
3.2
19.0
81
274
SPAT1260
SPAT
Consultation of another employee
2.4
18.8
161
780
H01CB03
ATC
lanreotide; parenteral
194.7
18.6
19
*
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
4.7
18.4
43
95
E21.0
ICD-10 Finland
Primary hyperparathyroidism
53.9
18.0
21
*
R06.0
ICD-10 Finland
Dyspnoea
2.1
18.0
234
1337
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
17.9
146
690
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
17.7
320
2056
A12AA04
ATC
calcium carbonate; oral
14.3
17.4
29
21
R5140
NOMESCO Finland
Monitoring the use of the aid
2.6
16.9
110
468
T99
ICPC
Endocr/metab/nutrit disease other
6.0
16.8
30
52
JN4AD
NOMESCO Finland
Body CT examination
2.6
16.6
107
453
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.4
16.4
124
566
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.2
16.4
172
902
205
Kela drug reimbursment
Chronic hypertension
2.1
16.3
188
1022
C10AC01
ATC
colestyramine; oral
4.7
16.3
38
84
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
48.6
16.1
19
*
WX110
NOMESCO Finland
Infiltration anesthesia
2.1
16.1
575
4585
S02.51
ICD-10 Finland
Fracture of tooth, open
2.6
15.8
102
431
BCA31
NOMESCO Finland
Endoscopic unilateral adrenalectomy
34.2
15.8
20
6
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
6.2
15.7
27
45
-54
ICPC
Repair/fix-suture/cast/prosth device
5.8
15.7
29
52
WX400
NOMESCO Finland
Inhalation anesthesy
3.6
15.6
54
160
E26.0
ICD-10 Finland
Primary hyperaldosteronism
86.9
15.6
17
*
XF404
NOMESCO Finland
Ambulatory ECG
2.8
15.6
83
318
E0000UV, ,
ATC
1.9
15.5
345
2343
JN7AQ
NOMESCO Finland
Somatostatin receptor SPET med low dose CT
163.3
15.5
16
*
SPAT1211
SPAT
Application of soft bandage
2.8
15.4
84
326
N06AX21
ATC
duloxetine; oral
2.4
15.4
120
554
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
4.2
15.3
41
101
-50
ICPC
Medication/prescr/renewal
3.8
15.3
48
133
SCA02
NOMESCO Finland
Preventive oral health care
2.6
15.3
100
426
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.9
15.2
243
1479
SPAT1238
SPAT
Brief therapy
5.4
15.2
30
57
-1, ,
SPAT
3.5
15.2
53
158
H02AB06
ATC
prednisolone; systemic
1.8
15.1
377
2650
N06AX16
ATC
venlafaxine; oral
2.2
15.0
141
705
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
+∞
14.6
14
*
R01AD12
ATC
fluticasone furoate; nasal
1.9
14.6
276
1773
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.9
14.5
44
119
XX9AN
NOMESCO Finland
Complementary isotope examination or additional picture
152.9
14.5
15
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.6
14.5
87
355
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.6
14.4
86
350
A02BC02
ATC
pantoprazole; systemic
1.9
14.3
529
4171
AA1AD
NOMESCO Finland
CT of head and brain
1.9
14.3
226
1368
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
6.0
14.1
25
43
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
4.5
13.9
34
78
KH1AD
NOMESCO Finland
CT of urinary organs
4.1
13.9
39
100
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.4
13.8
50
153
TPH07
NOMESCO Finland
Cathetrisation of artery
2.5
13.7
95
415
E66.01
ICD-10 Finland
Obesity due to excess calories
2.5
13.7
97
428
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
+∞
13.6
13
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
13.6
355
2504
J01FF01
ATC
clindamycin; systemic
1.9
13.6
221
1347
BCA30
NOMESCO Finland
Unilateral adrenalectomy
142.5
13.5
14
*
B03BA03
ATC
hydroxocobalamin; parenteral
3.3
13.4
51
161
N04BC06
ATC
cabergoline; oral
40.8
13.2
16
*
JN4CD
NOMESCO Finland
Very extensive body CT
4.0
13.1
37
95
UKC02
NOMESCO Finland
Cystoscopy
2.3
13.1
115
557
SPAT1294
SPAT
Other function in accordance with health social work nomenclature
5.7
13.0
24
43
C03DA01
ATC
spironolactone; oral
2.4
12.9
98
446
N05BA04
ATC
oxazepam; oral
1.9
12.9
220
1358
R4110, ,
SPAT
2.2
12.7
123
620
321
Kela drug reimbursment
Paricalcitol and cinacalcet
71.1
12.6
14
*
A12AA06
ATC
calcium lactate gluconate; oral
+∞
12.5
12
*
8240/3-C17.9
ICD-O-3
Neuroendocrine tumor, NOS, of small intestine, NOS
+∞
12.5
12
*
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
+∞
12.5
12
*
2592A
ICD-9 Finland
Other endocrine disorders, Carcinoid syndrome
+∞
12.5
12
*
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
132.1
12.5
13
*
T90
ICPC
Diabetes non-insulin dependent
1.9
12.3
184
1085
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.7
12.3
67
260
ZXD05
NOMESCO Finland
Urgent procedure
1.8
12.3
242
1558
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
12.2
218
1361
H02AA02
ATC
fludrocortisone; oral
16.2
12.2
19
12
R4180
NOMESCO Finland
Podiatric therapy
6.1
12.2
21
35
YHMAS, ,
NOMESCO Finland
12.7
12.2
21
17
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.4
12.1
92
418
SAA04
NOMESCO Finland
Special examination of mouth
3.0
12.1
55
193
OAB72
NOMESCO Finland
Weight control and weight loss guidance
10.3
12.1
23
23
R55
ICD-10 Finland
Syncope and collapse
2.4
12.0
90
407
N02AX02
ATC
tramadol; systemic, rectal
1.7
12.0
325
2292
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
5.2
11.8
24
47
H03BB01
ATC
carbimazole; oral
3.2
11.8
48
158
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
11.7
191
1157
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
11.7
158
899
A02BA02
ATC
ranitidine; systemic
2.0
11.6
149
832
E83.50
ICD-10 Finland
Hypercalcemia
11.3
11.6
21
19
T82
ICPC
Obesity
3.1
11.6
49
165
E03
ICD-10 Finland
Other hypothyroidism
2.7
11.6
65
256
Z31.5
ICD-10 Finland
Genetic counselling
2.7
11.5
62
239
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
11.5
326
2320
JN7AN
NOMESCO Finland
Somatostatin receptor isotope imaging
121.8
11.5
12
*
H05BX01
ATC
cinacalcet; oral
121.8
11.5
12
*
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
3.7
11.4
37
105
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
4.3
11.4
29
69
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
11.3
110
554
SAD02
NOMESCO Finland
Assessment of need for oral health care, extensive
3.2
11.3
45
146
C07AB02
ATC
metoprolol; systemic
2.0
11.3
142
787
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.6
11.2
68
278
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.2
11.2
103
508
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
11.2
116
600
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.3
11.1
89
414
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
5.4
11.1
22
42
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
10.3
11.1
21
21
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.6
10.9
66
270
SPAT1097
SPAT
Recording of ECG
2.1
10.8
113
585
SPAT1254
SPAT
Administration of medicine
2.1
10.8
109
557
Z56.5
ICD-10 Finland
Uncongenial work
28.5
10.8
14
5
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
10.7
185
1137
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
10.6
97
476
WZA10
NOMESCO Finland
Extensive medical or dental certificate
5.4
10.6
21
40
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
4.3
10.6
27
64
K02
ICD-10 Finland
Dental caries
2.5
10.6
66
274
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.6
10.5
61
244
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.1
10.5
105
534
R53
ICD-10 Finland
Malaise and fatigue
1.8
10.5
206
1315
R50.9
ICD-10 Finland
Fever, unspecified
2.0
10.5
128
702
318
Kela drug reimbursment
Teriparatide
111.5
10.4
11
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
111.5
10.4
11
*
C17.2
ICD-10 Finland
Malignant neoplasm: Ileum
111.5
10.4
11
*
E23.6
ICD-10 Finland
Other disorders of pituitary gland
+∞
10.4
10
*
E27.5
ICD-10 Finland
Adrenomedullary hyperfunction
+∞
10.4
10
*
N06AX11
ATC
mirtazapine; oral
1.7
10.4
270
1863
XKD00
NOMESCO Finland
Uroflowmetry
2.2
10.3
92
447
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
10.8
10.3
19
18
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.5
10.3
64
265
XX9TE
NOMESCO Finland
Compementary ultrasound examination
9.8
10.3
20
21
Z2221
NOMESCO Finland
Medical doctor
0.4
10.3
69
1422
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.9
10.3
30
79
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
19.1
10.3
15
8
J01DB01
ATC
cefalexin; oral
1.9
10.3
627
5428
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
10.3
120
647
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.4
10.3
73
322
N06AB04
ATC
citalopram; systemic
1.8
10.3
169
1022
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.3
10.3
38
118
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
4.0
10.2
29
75
130
Kela drug reimbursment
Malignant tumour
2.4
10.2
69
298
A02BC05
ATC
esomeprazole; systemic
1.7
10.1
311
2242
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
4.9
10.1
22
46
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
14.8
10.0
16
11
SPAT1240
SPAT
Therapeutic discussion
2.2
10.0
94
467
HMAK, ,
NOMESCO Finland
2.1
9.9
102
525
WX204
NOMESCO Finland
Axillary plexus blockaced
3.2
9.9
39
126
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
5.2
9.9
20
39
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
4.5
9.9
24
55
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.1
9.8
41
137
E29.1
ICD-10 Finland
Testicular hypofunction
10.8
9.8
18
17
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
9.8
183
1149
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
3.2
9.7
38
122
N03AE01
ATC
clonazepam; systemic
2.7
9.7
52
200
N05AH04
ATC
quetiapine; oral
1.9
9.7
148
873
N02AA05
ATC
oxycodone; systemic
1.9
9.7
130
735
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
9.6
98
502
C03AA03
ATC
hydrochlorothiazide; oral
2.4
9.6
66
287
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.3
9.6
74
339
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
9.4
195
1258
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
9.4
170
1054
R51
ICD-10 Finland
Headache
2.6
9.4
55
221
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
3.4
9.4
33
99
R06AE07
ATC
cetirizine; oral
1.6
9.4
342
2556
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
9.4
153
920
7834C
ICD-9 Finland
Symptoms concerning nutrition, metabolism and development, Lack of expected normal physiological development[HÄIRIINTYNYT PITUUSKASVU]
+∞
9.4
9
*
H05AA02
ATC
teriparatide; parenteral
+∞
9.4
9
*
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.7
9.4
50
192
D07AC01
ATC
betamethasone; topical
1.6
9.3
274
1942
ZXH04
NOMESCO Finland
Procedure performed in other inpatient unit
9.7
9.3
18
19
D82
ICPC
Teeth/gum disease
1.6
9.2
297
2152
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.0
9.2
40
137
A04AA02
ATC
granisetron; systemic, transdermal
2.5
9.2
58
242
SPAT1094
SPAT
Continuous Positive Airway Pressure
7.9
9.2
20
26
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
9.2
82
399
F33
ICD-10 Finland
Recurrent depressive disorder
3.6
9.2
30
86
L01BA01
ATC
methotrexate; systemic
3.3
9.1
34
106
WZC00, ,
SPAT
1.9
9.1
122
689
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.0
9.1
109
593
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.5
9.0
56
232
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
8.9
190
1234
XLA10, ,
NOMESCO Finland
2.8
8.9
44
162
SPAT1324
SPAT
Screening procedure
0.4
8.9
35
912
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
5.0
8.9
19
39
ZXA10
NOMESCO Finland
Bilateral
1.8
8.9
140
833
L04AX01
ATC
azathioprine; systemic
3.0
8.8
39
135
WX610
NOMESCO Finland
Patient controlled analgesia
9.6
8.8
17
18
C07AB07
ATC
bisoprolol; oral
1.6
8.8
329
2465
A10BK03
ATC
empagliflozin; oral
2.1
8.8
86
434
Y0099
ICD-8 Finland
Investigation of endocrine system and metabolism
14.2
8.7
14
10
L68.0
ICD-10 Finland
Hirsutism
14.2
8.7
14
10
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
4.3
8.7
22
52
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.1
8.7
36
120
L04AA06
ATC
mycophenolic acid; systemic
4.6
8.6
20
44
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
8.4
8.6
18
22
WZC30
NOMESCO Finland
Teaching
1.8
8.6
132
779
R68.8
ICD-10 Finland
Other specified general symptoms and signs
9.1
8.6
17
19
ED1AA
NOMESCO Finland
Mandibular X-ray examination
10.2
8.6
16
16
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.7
8.5
213
1441
D07AC13
ATC
mometasone; topical
1.7
8.5
218
1484
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.0
8.5
97
517
B01AB10
ATC
tinzaparin; parenteral
2.1
8.5
89
460
B81
ICPC
Anaemia vit B12/folate deficiency
3.2
8.5
34
111
JAH01
NOMESCO Finland
Laparoscopy
2.8
8.5
43
161
S02.5
ICD-10 Finland
Fracture of tooth
3.5
8.4
29
86
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
8.4
313
2334
-56
ICPC
Dressing/pressure/compress/tamponade
6.8
8.4
20
30
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
4.7
8.4
19
41
C08CA02
ATC
felodipine; oral
2.3
8.4
66
305
E21.5
ICD-10 Finland
Disorder of parathyroid gland, unspecified
+∞
8.3
8
*
BB1BQ
NOMESCO Finland
Extensive scintigraphy of parathyroid gland, 2 isotopes, SPECT and low-dose CT
+∞
8.3
8
*
102
Kela drug reimbursment
Diabetes insipidus
+∞
8.3
8
*
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
+∞
8.3
8
*
E66
ICD-10 Finland
Obesity
2.5
8.2
53
224
A06AD11
ATC
lactulose; oral
2.0
8.2
99
539
N02BE01
ATC
paracetamol; systemic, rectal
2.0
8.2
668
6017
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
8.2
232
1619
N02AA01
ATC
morphine; systemic, rectal
4.6
8.2
19
42
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
8.1
98
533
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.4
8.1
56
244
E03.89
ICD-10 Finland
Other specified hypothyroidism
2.9
8.1
37
131
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.2
8.1
32
104
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.6
8.1
48
195
ZX070
NOMESCO Finland
Intensity modified radiotherapy
4.2
8.0
21
51
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
3.0
8.0
36
126
N06AX12
ATC
bupropion; oral
2.2
8.0
66
311
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.1
8.0
33
110
D07AD01
ATC
clobetasol; topical
1.8
8.0
131
788
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
8.0
409
3268
SPAT1104
SPAT
Monitoring of emergency patient
2.5
7.9
51
215
JN6AD
NOMESCO Finland
CT of torso and neck
4.5
7.9
19
43
N18.8
ICD-10 Finland
Other chronic renal failure
4.7
7.9
18
39
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
7.9
155
981
GD2SN
NOMESCO Finland
Lung ventilation SPECT
13.2
7.9
13
10
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.2
7.9
30
95
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.1
7.8
76
382
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
3.1
7.8
32
106
N03AX16
ATC
[U] pregabalin
1.7
7.8
168
1091
EBA10
NOMESCO Finland
Operative extraction of tooth
1.9
7.8
105
593
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
6.5
7.7
19
30
XKC03
NOMESCO Finland
Water cystometry
3.3
7.7
29
91
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
15.2
7.7
12
8
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
3.5
7.7
26
76
M79.6
ICD-10 Finland
Pain in limb
1.5
7.7
339
2610
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
6.0
7.7
20
34
SPAT1298
SPAT
Other function in accordance with nutritional therapy nomenclature
7.5
7.7
17
23
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
7.7
157
1004
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.9
7.7
36
129
WX320
NOMESCO Finland
Spinalanesthesy
1.7
7.7
184
1228
R01AD08
ATC
fluticasone; nasal
1.6
7.7
219
1528
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.3
7.6
60
277
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.0
7.6
84
443
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
4.2
7.6
20
49
-1, ,
ICD-10 Finland
2.5
7.6
47
195
C08CA01
ATC
amlodipine; oral
1.6
7.5
256
1858
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
7.5
146
921
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
7.5
164
1068
A41.9
ICD-10 Finland
Sepsis, unspecified
3.3
7.5
28
88
N91.1
ICD-10 Finland
Secondary amenorrhoea
6.6
7.4
18
28
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
3.4
7.4
26
78
E21.2
ICD-10 Finland
Other hyperparathyroidism
80.9
7.4
8
*
E21.1
ICD-10 Finland
Secondary hyperparathyroidism, not elsewhere classified
80.9
7.4
8
*
JN4SR
NOMESCO Finland
Very extensive PET-CT of receptors in whole body
80.9
7.4
8
*
E20.9
ICD-10 Finland
Hypoparathyroidism, unspecified
80.9
7.4
8
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
7.8
7.4
16
21
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.5
7.4
46
191
J45
ICD-10 Finland
Asthma
2.0
7.4
87
470
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.7
7.3
23
64
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
7.3
222
1567
N03AX09
ATC
lamotrigine; oral
2.5
7.3
47
198
M47.82
ICD-10 Finland
Other spondylosis, cervical region
2.7
7.3
38
144
-51
ICPC
I&d/flush/aspiration
6.9
7.3
17
25
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
7.3
255
1860
A10AE04
ATC
insulin glargine; parenteral
2.0
7.3
76
392
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
+∞
7.3
7
*
E22.9
ICD-10 Finland
Hyperfunction of pituitary gland, unspecified
+∞
7.3
7
*
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
+∞
7.3
7
*
E20.8
ICD-10 Finland
Other hypoparathyroidism
+∞
7.3
7
*
BB1AN
NOMESCO Finland
Parathyroid gland isotope imaging, 1 isotope
+∞
7.3
7
*
E27.2
ICD-10 Finland
Addisonian crisis
+∞
7.3
7
*
XX7JT
NOMESCO Finland
Somatostatin isotope ablative therapy
+∞
7.3
7
*
SPAT1325
SPAT
Vaccination
1.6
7.3
226
1604
ZXA00
NOMESCO Finland
Right side
0.5
7.3
67
1248
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.8
7.3
108
629
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.0
7.3
87
472
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
4.4
7.2
18
42
K29.4
ICD-10 Finland
Chronic atrophic gastritis
4.4
7.2
18
42
UJF92
NOMESCO Finland
Capsular endoscopy
3.7
7.2
22
60
C08DB01
ATC
diltiazem; oral
2.8
7.2
35
128
C17.9
ICD-10 Finland
Malignant neoplasm: Small intestine, unspecified
30.3
7.2
9
*
ZYC01, ,
SPAT
2.0
7.1
85
460
QXA20
NOMESCO Finland
Skin abrasion, unspecified location
20.2
7.1
10
5
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
6.7
7.1
17
26
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.8
7.1
126
773
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
7.1
138
870
C05AA08
ATC
fluocortolone; rectal, topical
1.9
7.0
100
574
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
4.3
7.0
18
43
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.5
7.0
43
178
E000003, ,
ATC
2.6
7.0
39
154
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
6.9
85
466
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
6.2
6.8
17
28
E86
ICD-10 Finland
Volume depletion
3.7
6.8
21
58
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.3
6.8
17
40
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
16.9
6.8
10
6
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.8
6.8
34
127
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
6.7
55
258
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.3
6.7
25
78
-64
ICPC
Encounter/prob initiated by provider
4.0
6.7
19
49
N05AF03
ATC
chlorprothixene; systemic
3.4
6.7
24
73
XJH00
NOMESCO Finland
Transanal ultrasonography
2.7
6.7
35
133
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
3.1
6.7
28
94
R11
ICD-10 Finland
Nausea and vomiting
2.0
6.7
72
376
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.2
6.6
26
84
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
7.9
6.6
14
18
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
3.6
6.6
21
59
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
3.4
6.6
23
69
G02CB03
ATC
cabergoline; oral
12.4
6.6
11
9
ZXC50
NOMESCO Finland
Cryotherapy
3.1
6.6
27
90
A55
ICPC
General and Unspecified, Local injection/infiltration
6.9
6.5
15
22
F32
ICD-10 Finland
Depressive episode
2.3
6.5
49
222
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
6.5
105
626
J01FA09
ATC
clarithromycin; systemic
1.5
6.5
231
1684
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.4
6.5
45
197
SPAT1284
SPAT
Extensive health certificate
3.5
6.5
22
65
E23.05
ICD-10 Finland
Lack of TSH
70.4
6.4
7
*
C09CA01
ATC
losartan; oral
1.6
6.4
176
1209
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
14.5
6.4
10
7
N05BA01
ATC
diazepam; systemic, rectal
1.8
6.4
97
569
N03AX12
ATC
[U] gabapentin; oral
1.7
6.4
119
741
SPAT1110
SPAT
Measurement of pain intensity
8.2
6.3
13
16
SPAT1341
SPAT
Referral to physician or dentist
8.2
6.3
13
16
127
Kela drug reimbursment
Transplant complication
5.6
6.3
17
31
SPAT1139
SPAT
Nutrition survey
2.9
6.3
29
103
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
3.3
6.3
23
71
A10BA02
ATC
metformin; oral
1.6
6.3
189
1325
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.2
6.3
50
232
E23.2
ICD-10 Finland
Diabetes insipidus
+∞
6.3
6
*
E20.0
ICD-10 Finland
Idiopathic hypoparathyroidism
+∞
6.3
6
*
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
+∞
6.3
6
*
2520A
ICD-9 Finland
Disorders of parathyroid gland, Hyperparathyroidism
+∞
6.3
6
*
E21
ICD-10 Finland
Hyperparathyroidism and other disorders of parathyroid gland
+∞
6.3
6
*
E89.6
ICD-10 Finland
Postprocedural adrenocortical(-medullary) hypofunction
+∞
6.3
6
*
301
Kela drug reimbursment
Growth hormone
+∞
6.3
6
*
E25.01
ICD-10 Finland
Congenital adrenal hyperplasia
+∞
6.3
6
*
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
6.3
6
*
WZC15, ,
NOMESCO Finland
7.1
6.2
14
20
N32.83
ICD-10 Finland
Nozzle synergy in the bladder neck
26.9
6.2
8
*
E28.3
ICD-10 Finland
Primary ovarian failure
26.9
6.2
8
*
A11CC02
ATC
dihydrotachysterol; oral
26.9
6.2
8
*
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
26.9
6.2
8
*
JLC10
NOMESCO Finland
Distal pancreatectomy
26.9
6.2
8
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
2.0
6.2
66
343
A10AB05
ATC
insulin aspart; parenteral
2.1
6.2
61
308
SPAT1131
SPAT
Colonoscopy
2.9
6.2
29
104
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
6.2
198
1407
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
3.6
6.2
20
57
TK800
NOMESCO Finland
Hemodialysis
4.0
6.2
17
43
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
6.2
69
366
SCA03
NOMESCO Finland
Preventive oral health care, extensive
2.4
6.2
43
189
B01AB05
ATC
enoxaparin; parenteral
1.5
6.1
216
1569
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.6
6.1
34
134
M81.4
ICD-10 Finland
Drug-induced osteoporosis
12.6
6.1
10
8
SPAT1353
SPAT
Intensive monitoring
12.6
6.1
10
8
J01CA02
ATC
pivampicillin; oral
2.8
6.1
30
111
SPAT1307
SPAT
Psychosocial counselling and guidance
2.3
6.1
47
216
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.3
6.1
45
203
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
8.7
6.1
12
14
K92.1
ICD-10 Finland
Melaena
2.4
6.1
39
165
D06BX01
ATC
metronidazole; topical
1.8
6.1
85
486
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.5
6.0
38
159
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.4
6.0
41
178
M79.7
ICD-10 Finland
Fibromyalgia
2.6
6.0
34
135
R42
ICD-10 Finland
Dizziness and giddiness
1.6
6.0
159
1082

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
377
552
12.69
273.39
4.6
3.6
—
—
—
0
0
343
497
11.85
248.22
6.3
3.1
1.22
1.23
mmol/l
0.18
305
416
137
109
15.15
144.91
3.9
2.4
2.52
2.53
mmol/l
0.01
106
72
137
132
12.47
128.23
3.7
2.7
—
—
—
0
0
264
623
5.99
112.40
3.4
1.9
308.40
377.17
nmol/l
4.22
250
582
242
578
5.70
100.57
4.6
4.7
0.56
0.59
%
0.07
54
174
238
570
5.65
98.41
4.7
5.0
0.10
0.15
%
0.43
51
156
239
586
5.51
95.99
4.7
5.3
0.02
0.20
%
1.35
50
143
242
601
5.46
95.75
4.6
4.9
0.65
1.02
%
0.98
55
188
123
156
9.23
93.37
3.4
2.8
57.65
57.84
%
0.04
123
156
462
1999
4.40
87.32
4.5
3.1
0.01
0.01
estimate
0.31
294
601
144
239
7.22
86.36
3.8
1.3
324.52
303.16
mu/l
0.36
127
215
97
103
10.66
83.97
4.3
2.7
12.15
6.99
pmol/l
0.81
97
103
578
3025
4.94
82.10
25.5
10.8
0.00
0.00
e9/l
0.55
551
2491
397
1637
4.02
78.06
6.8
4.9
—
—
—
0
0
445
1986
4.04
77.83
4.7
3.9
0.00
0.01
estimate
0.38
318
700
415
1930
3.57
64.71
6.6
3.6
7.40
7.40
ph
0.11
350
1348
314
1227
3.68
64.34
3.1
2.6
472.60
524.81
mosm/kgh2o
3.93
285
1076
100
166
6.79
59.21
1.7
1.3
11.32
9.14
u/l
0.60
71
132
500
2740
3.46
57.30
4.6
3.0
—
—
—
0
0
316
1318
3.41
57.16
2.5
1.7
27197128.69
20499545.78
pmol/l
0.08
239
1122
159
439
4.32
52.65
4.5
3.6
4.44
4.61
pmol/l
0.83
140
394
487
2734
3.22
51.40
4.6
3.6
0.01
0.03
estimate
1.18
305
616
320
1422
3.18
50.89
3.3
2.5
6.46
6.28
e6/l
0.06
292
1294
59
70
9.06
46.52
2.5
2.0
31.27
32.14
pg
0.56
59
70
56
78
7.68
38.62
2.5
2.1
0.91
0.92
%
0.04
37
50
417
2415
2.63
36.89
5.2
3.4
29.74
77.58
ng/l
0.97
317
1604
49
62
8.38
36.60
2.3
1.2
0.35
0.17
nmol/l
0.60
37
44
340
1791
2.64
36.50
3.7
3.0
0.38
0.42
e6/l
0.24
294
1287
463
2832
2.65
36.40
17.2
12.1
1.15
1.20
inr
1.57
432
2321
48
63
8.07
34.77
2.4
1.2
—
—
nmol/l
—
0
0
51
72
7.53
34.72
2.4
1.2
0.63
0.56
nmol/l
0.65
51
66
192
781
2.96
33.68
7.3
5.2
1.02
1.04
mmol/l
0.76
182
729
457
2848
2.54
33.43
8.3
5.7
1.22
1.21
mmol/l
3.08
420
2627
80
190
4.59
31.55
4.9
3.3
1.70
1.39
mg/l
1.91
70
170
378
2203
2.44
31.37
7.3
6.2
—
—
—
0
0
383
2249
2.43
31.21
4.2
3.4
2.34
2.35
mmol/l
1.05
369
2045
227
1067
2.61
29.69
4.6
3.0
0.81
0.82
mmol/l
0.28
213
1021
523
3589
2.50
29.25
4.8
3.7
0.00
0.00
estimate
0.50
335
742
525
3616
2.50
29.00
4.7
3.7
0.00
6.05
estimate
1.08
334
750
312
1718
2.39
28.80
3.7
2.9
—
0.00
estimate
—
0
6
179
763
2.77
28.29
1.4
1.3
—
—
—
0
0
477
3189
2.36
27.55
9.4
6.4
1.22
1.21
mmol/l
0.36
260
2765
200
916
2.61
27.30
3.2
2.3
22.77
23.02
%
0.09
169
858
520
3645
2.38
26.35
4.7
3.8
0.00
0.02
estimate
1.20
321
706
113
388
3.25
26.16
1.9
1.3
21.47
25.14
iu/l
0.52
83
336
346
2059
2.26
25.92
3.7
2.6
60.06
99.84
u/l
0.51
304
1913
359
2186
2.23
25.23
4.3
3.3
—
0.89
—
0
9
45
80
5.92
24.55
2.9
2.4
—
—
—
0
0
216
1077
2.41
24.23
3.1
2.3
12.81
13.26
umol/l
0.38
188
1002
340
2075
2.17
23.22
3.8
3.1
123.80
93.89
e6/l
0.17
291
1561
203
1008
2.39
22.81
3.2
2.3
2.38
2.35
g/l
0.24
175
934
44
83
5.57
22.55
2.3
2.6
—
—
—
0
0
653
5249
2.85
21.99
8.7
4.5
15.57
14.66
pmol/l
12.85
602
4842
585
4533
2.31
20.22
5.9
3.9
—
8418.25
—
0
12
480
3448
2.08
20.16
8.1
6.4
10.52
10.89
umol/l
0.16
450
3293
447
3141
2.04
19.79
8.5
6.5
0.68
0.70
%
0.43
428
2939
50
119
4.43
19.56
1.8
1.3
0.36
0.41
nmol/l
0.21
36
97
447
3150
2.03
19.52
8.5
6.5
8.76
8.70
%
0.17
428
2960
446
3146
2.03
19.36
8.4
6.4
2.53
2.82
%
2.25
426
2949
25
31
8.31
18.86
2.5
2.3
519.79
486.70
min
0.59
19
20
369
2454
1.99
18.74
4.3
3.7
97.56
108.53
e6/l
0.11
313
1659
123
528
2.59
18.62
3.7
2.8
9.61
10.93
g/l
3.25
105
492
280
1699
2.03
18.36
2.8
2.2
3.53
2.89
mg/l
3.42
245
1459
110
452
2.68
18.16
4.6
2.2
11.83
13.52
nmol/l
1.29
94
424
407
2823
1.96
18.05
6.0
4.8
34.75
36.16
g/l
5.61
365
2661
427
3011
1.97
18.03
4.1
2.4
78.79
76.97
nmol/l
0.69
399
2744
95
363
2.85
18.02
1.2
1.2
—
—
—
0
0
449
3230
1.97
17.78
8.3
6.4
26.91
28.20
%
1.94
431
3065
26
39
6.87
16.67
2.4
2.3
708.42
572.91
ml
0.68
19
23
103
427
2.64
16.66
2.3
1.6
1.12
1.33
g/l
0.83
95
399
272
1679
1.97
16.65
7.0
4.1
—
—
—
0
0
172
904
2.17
16.27
1.5
1.2
—
—
—
0
0
660
5555
2.54
16.21
28.3
18.1
13.85
13.55
%
6.20
654
5499
499
3784
1.95
16.18
7.0
4.7
6.70
6.59
mmol/l
0.52
483
3564
607
4992
2.12
14.81
12.8
8.0
79.39
78.26
u/l
0.30
583
4731
178
983
2.06
14.63
3.0
1.7
1890.00
1210.64
nmol/l
13.37
128
732
118
555
2.34
14.48
1.5
1.4
—
—
—
0
0
298
1984
1.83
13.88
3.4
3.0
—
—
—
0
0
92
396
2.51
13.70
3.7
3.2
7.42
7.42
ph
0.11
81
327
75
1636
0.40
13.39
4.3
3.7
—
0.21
—
0
14
120
587
2.24
13.38
2.1
2.3
0.20
0.22
g/l
0.98
106
557
452
3449
1.78
12.94
8.3
6.4
0.04
0.04
e9/l
0.54
419
2968
451
3444
1.77
12.82
8.3
6.4
0.61
0.57
e9/l
3.41
419
2963
538
4329
1.85
12.82
5.9
4.4
3521.86
1321.27
e6/l
—
7
66
157
866
2.03
12.79
1.3
1.3
—
—
—
0
0
176
1011
1.97
12.78
1.5
1.4
344.52
534.63
titre
0.92
31
227
387
2835
1.75
12.67
2.4
1.9
1.53
1.35
mmol/l
2.53
223
2427
23
41
5.76
12.48
2.0
1.6
20.60
39.67
%
1.48
15
27
22
38
5.93
12.32
2.4
3.7
15.15
16.98
%
1.10
22
38
106
510
2.26
12.26
4.3
2.8
74.01
71.82
e9/l
0.25
79
366
286
1940
1.77
12.12
2.8
2.1
153.64
194.28
u/l
1.10
256
1847
56
201
2.93
11.85
1.3
1.4
242.67
291.70
ug/g
0.95
32
126
558
4587
1.84
11.84
5.6
4.4
—
3.21
—
0
10
453
3520
1.72
11.56
8.4
6.4
1.83
1.94
e9/l
1.41
424
3110
433
3331
1.71
11.40
4.5
3.1
130.65
111.25
ug/l
0.96
383
3129
256
1706
1.76
11.39
1.6
1.3
0.56
1.70
u/ml
2.68
121
488
78
1576
0.44
11.20
3.3
3.8
1.02
1.02
kg/l
0.50
58
1050
60
232
2.72
11.07
1.8
1.8
12.13
2.32
ug/l
0.44
49
211
455
3566
1.70
11.00
8.7
6.7
0.17
0.19
e9/l
1.12
422
3121
26
59
4.53
10.80
1.3
1.1
—
—
—
0
0
264
1806
1.71
10.53
3.4
3.1
1036.61
1064.51
ng/l
0.05
204
1531
22
45
5.01
10.31
1.2
1.3
—
—
—
0
0
38
122
3.23
9.74
4.7
4.4
21.19
351.07
u/ml
0.99
32
117
21
27
7.97
9.67
1.5
1.3
0.00
0.00
estimate
-0.00
21
27
26
66
4.04
9.39
1.9
1.7
76.38
57.19
%
1.82
16
48
17
16
10.84
9.32
2.7
1.1
58.29
65.00
nmol/24h
0.15
17
16
23
54
4.36
9.17
3.6
2.0
44.20
40.61
%
0.62
23
54
17
17
10.20
9.06
2.2
1.6
30.29
26.24
%
0.44
17
17
154
938
1.81
9.05
2.9
2.5
134.51
108.66
ug/g
0.62
106
750
471
3825
1.62
9.03
12.8
9.8
4.39
4.01
e9/l
2.99
440
3339
85
424
2.13
8.93
2.7
3.1
88.91
75.05
ng/l
0.39
45
377
38
129
3.05
8.89
3.2
4.8
—
—
—
0
0
284
2052
1.62
8.82
3.9
3.4
42.66
41.33
mg/l
0.05
164
1292
16
15
10.87
8.82
1.3
1.1
—
—
—
0
0
66
300
2.32
8.69
1.4
1.2
—
1.90
—
0
16
26
70
3.81
8.68
2.5
5.4
7.53
7.16
mmol/l
0.22
26
63
303
2235
1.60
8.58
3.8
3.3
7.32
7.62
mmol/l
0.47
224
1898
36
122
3.05
8.45
1.4
1.3
70.74
61.56
mmol/l
0.52
27
109
286
2088
1.60
8.42
6.1
4.1
8.52
7.42
mg/mmol
0.24
165
1276
676
6113
2.05
8.22
9.5
5.5
1.58
1.88
mu/l
8.10
616
5703
234
1655
1.60
7.74
2.8
2.6
338.42
333.94
umol/l
0.23
203
1477
141
875
1.75
7.69
2.8
3.3
3.85
5.51
e9/l
1.52
133
769
370
2913
1.53
7.55
3.0
3.3
6.00
6.20
ph
3.55
234
1680
192
1305
1.63
7.43
3.8
2.8
2.46
2.44
mmol/l
1.29
184
1170
71
359
2.08
7.20
1.2
1.1
—
135.67
titre
—
0
9
46
194
2.46
7.17
1.1
1.2
80.00
97.20
titre
—
8
25
126
772
1.76
7.16
1.8
1.6
—
—
—
0
0
114
682
1.79
7.02
3.0
2.8
1.81
1.80
%
0.05
97
608
669
6097
1.88
6.92
7.6
6.0
40.51
38.85
mmol/mol
4.01
603
5750
64
1188
0.50
6.85
3.5
3.8
29.66
310.47
ng/l
5.46
42
866
62
304
2.13
6.82
2.3
2.3
9774.57
6330.26
u/l
0.21
17
138
209
1483
1.57
6.66
1.8
1.5
2.37
2.38
g/l
0.04
152
930
22
65
3.46
6.46
1.2
1.3
—
—
—
0
0
15
23
6.63
6.36
2.2
1.4
3.00
7.29
%
—
6
7
89
509
1.85
6.34
1.9
3.1
67.54
67.27
g/l
0.14
82
477
22
66
3.40
6.32
1.2
1.3
0.17
0.35
g/l
—
5
48
22
66
3.40
6.32
1.2
1.3
5.55
6.71
g/l
—
5
49
22
66
3.40
6.32
1.2
1.3
4.65
2.91
g/l
—
5
48
196
1392
1.55
6.16
1.5
1.3
44.34
31.27
iu/ml
0.31
59
412
76
421
1.90
5.97
2.1
2.7
—
—
—
0
0
716
6735
2.32
5.97
26.9
13.0
—
—
—
0
0
86
498
1.82
5.88
1.5
1.3
225.32
241.11
u/ml
0.06
76
459
35
143
2.52
5.86
3.8
2.4
81.14
78.76
ug/min
0.02
23
89
702
6576
2.02
5.56
26.6
16.4
139.50
139.67
mmol/l
1.09
691
6441
136
914
1.60
5.38
2.5
2.0
—
—
—
0
0
18
53
3.45
5.33
1.2
1.1
114.39
111.19
pmol/l
0.09
18
53
702
6590
1.98
5.31
27.0
16.5
3.95
3.95
mmol/l
0.04
691
6439
31
126
2.52
5.27
1.3
1.3
—
—
—
0
0
177
1268
1.52
5.26
1.4
1.3
7.14
11.47
u/ml
0.60
76
498
41
196
2.15
4.86
1.1
1.2
—
880.00
—
0
5
205
1536
1.46
4.84
1.8
1.7
0.93
1.11
mg/l
0.76
143
1191
15
42
3.62
4.78
1.1
1.7
0.73
2.10
u/field
0.91
15
31
22
527
0.40
4.60
2.4
2.2
6.00
6.10
ph
0.20
15
349
289
2326
1.39
4.53
3.2
3.2
30.82
31.81
u/l
0.24
261
2202
19
66
2.93
4.36
1.4
1.2
—
—
—
0
0
8
9
8.97
4.28
1.9
1.0
—
—
—
0
0
516
4590
1.40
4.27
4.5
3.2
58.90
45.19
u/l
1.73
465
4346
40
202
2.04
4.15
3.1
4.0
40.62
40.90
mg/l
—
10
177
40
202
2.04
4.15
3.1
4.0
47.35
71.06
mg/l
—
10
179
9
279
0.31
4.03
1.7
1.9
—
—
—
0
0
21
81
2.64
4.00
3.3
2.8
—
—
—
0
0
31
144
2.20
3.98
1.4
1.4
—
—
—
0
0
12
27
4.50
3.94
1.1
1.3
148.50
161.77
mmol/24h
0.25
12
27
26
114
2.33
3.82
1.2
1.1
16.17
61.49
iu/ml
0.44
11
29
687
6498
1.66
3.79
23.8
14.5
19.39
22.94
mg/l
2.09
630
5311
6
5
12.08
3.77
2.2
1.0
—
—
—
0
0
65
1014
0.61
3.67
4.9
2.9
9.65
3.18
e6/l
0.87
33
460
234
1871
1.36
3.67
1.9
1.7
20.25
20.41
nmol/l
0.05
178
1603
322
2710
1.33
3.56
2.2
2.1
—
—
—
0
0
28
132
2.16
3.49
1.5
1.4
158.00
162.90
au/ml
—
5
37
26
121
2.19
3.35
1.0
1.1
—
—
—
0
0
15
54
2.81
3.27
1.0
1.0
—
—
—
0
0
115
829
1.46
3.25
1.9
1.4
—
—
—
0
0
36
636
0.54
3.24
14.0
3.4
5.76
5.77
kpa
0.02
36
616
48
282
1.75
3.20
1.4
1.2
—
—
—
0
0
29
145
2.04
3.14
1.3
1.2
20.84
10.43
e6/l
0.37
19
108
29
540
0.52
3.11
14.6
2.9
4.76
4.55
kpa
0.21
29
521
6
8
7.55
3.06
1.3
1.0
—
—
—
0
0
29
147
2.01
3.03
1.3
1.3
440.14
103.46
e6/l
0.53
22
112
45
726
0.60
2.92
1.2
1.4
—
—
—
0
0
33
574
0.56
2.83
1.3
1.2
—
—
—
0
0
57
862
0.63
2.82
13.5
6.8
105.05
104.14
mmol/l
0.99
57
862
40
232
1.76
2.81
1.5
1.2
—
—
—
0
0
15
334
0.44
2.69
24.6
2.9
0.78
0.62
%
0.62
15
334
40
236
1.73
2.67
1.3
1.3
—
—
—
0
0
37
609
0.59
2.61
13.6
3.4
1.96
2.00
mmol/l
0.03
32
526
28
149
1.91
2.59
1.1
1.2
3.92
3.65
mmol/l
0.47
23
139
5
165
0.30
2.57
1.6
3.1
7.20
2.03
index
—
5
88
107
796
1.40
2.56
1.7
1.7
—
—
—
0
0
39
630
0.60
2.56
12.9
3.4
7.37
7.38
ph
0.71
25
348
36
209
1.76
2.55
2.6
1.9
172.55
261.70
ug/l
0.94
31
196
22
109
2.05
2.48
1.2
1.8
0.84
0.81
g/l
—
5
86
49
314
1.60
2.42
2.9
2.0
6.53
8.20
iu/ml
—
6
76
5
8
6.28
2.37
1.4
1.1
—
—
—
0
0
12
46
2.63
2.37
1.2
1.1
47.15
31.71
mg/l
—
6
35
19
91
2.12
2.34
1.1
1.1
1.43
1.46
g/l
0.10
19
84
7
187
0.37
2.30
2.3
1.6
—
—
—
0
0
32
528
0.59
2.29
13.8
8.3
—
—
—
0
0
75
534
1.45
2.29
1.3
1.2
104.21
140.47
u/ml
0.40
24
230
656
6258
1.38
2.27
6.0
4.9
5.99
5.87
mmol/l
1.28
577
5786
15
67
2.26
2.19
1.6
1.3
—
—
—
0
0
7
181
0.38
2.18
2.0
1.5
—
—
—
0
0
39
600
0.63
2.11
1.7
1.8
3.43
3.44
mmol/l
0.00
27
431
10
235
0.42
2.10
1.9
1.5
63.04
62.50
ug/l
—
10
193
11
43
2.58
2.08
1.4
1.5
86.27
75.49
umol/l
0.51
11
43
9
31
2.93
2.07
2.3
1.5
28.67
28.50
umol/l
—
9
26
180
2145
0.79
2.06
2.5
2.3
—
—
—
0
0
13
273
0.47
2.05
1.4
1.1
1.45
1.55
g/l
0.60
13
273
11
44
2.52
2.02
1.2
1.0
279.33
224.06
mg/l
—
6
36
35
545
0.62
2.01
6.0
3.6
7.38
7.35
ph
1.21
29
383
9
203
0.44
1.98
1.7
1.2
—
—
—
0
0
14
278
0.49
1.90
1.4
1.1
0.79
0.90
g/l
1.39
14
278
18
93
1.96
1.86
2.6
3.2
1.22
1.14
%
0.06
18
85
30
475
0.62
1.86
1.6
2.4
6.37
6.69
ug/l
0.05
24
428
34
214
1.62
1.85
2.9
2.3
—
—
—
0
0
24
137
1.78
1.85
2.1
2.2
—
—
—
0
0
91
698
1.35
1.84
1.4
1.5
—
—
—
0
0
5
12
4.19
1.82
3.8
1.4
—
—
—
0
0
174
1462
1.25
1.76
5.6
5.0
1.70
2.27
ug/l
1.35
149
1325
7
24
2.93
1.72
3.9
1.2
260.86
102.69
nmol/l
—
7
16
64
857
0.72
1.71
1.6
1.5
—
—
—
0
0
29
180
1.64
1.69
2.3
2.2
6.73
11.70
mg/l
2.66
24
168
171
1441
1.24
1.68
2.4
1.9
—
—
—
0
0
8
31
2.60
1.66
1.1
1.4
117.50
150.39
nmol/l
—
8
31
24
143
1.70
1.63
1.6
1.2
284.60
243.39
u/ml
0.30
15
84
45
634
0.69
1.62
1.7
2.0
0.14
0.04
estimate
0.32
22
136
44
621
0.69
1.61
5.3
2.6
31.00
41.54
u/l
0.75
38
525
34
223
1.55
1.59
2.1
2.0
2.21
28.15
iu/l
0.55
17
97
704
6858
1.42
1.55
17.6
11.6
26.97
25.87
u/l
1.04
676
6682
104
835
1.28
1.54
1.9
1.6
—
—
—
0
0
117
958
1.26
1.48
2.1
1.9
31.12
29.21
s
3.64
111
930
145
1217
1.24
1.48
1.9
1.7
—
—
—
0
0
9
37
2.45
1.48
1.9
1.2
—
0.51
—
0
16
10
45
2.24
1.47
1.3
1.6
—
—
—
0
0
10
45
2.24
1.47
1.0
1.0
—
—
—
0
0
24
376
0.63
1.46
19.2
3.1
24.43
24.43
mmol/l
0.00
24
371
174
2013
0.82
1.46
6.1
6.2
—
—
—
0
0
31
204
1.54
1.45
2.5
2.6
—
—
—
0
0
16
272
0.58
1.36
4.6
3.2
—
—
—
0
0
36
249
1.47
1.35
1.7
2.1
1.50
1.46
g/l
0.11
28
224
8
36
2.24
1.24
5.6
2.9
401.25
884.58
u/ml
—
8
36
35
247
1.44
1.21
2.2
1.8
—
—
—
0
0
8
38
2.12
1.18
2.9
3.7
7.90
8.40
mmol/l
—
8
38
17
271
0.62
1.15
2.9
3.4
24.57
25.22
mmol/l
0.28
17
261
11
58
1.91
1.12
1.0
1.1
—
—
—
0
0
21
136
1.56
1.09
1.5
1.7
—
—
—
0
0
722
7101
1.42
1.09
35.9
22.4
261.29
254.61
e9/l
1.55
712
6978
77
625
1.26
1.09
4.4
4.6
6.18
26.40
ug/l
0.92
57
517
722
7102
1.42
1.08
35.7
22.3
91.05
90.87
fl
0.46
713
7036
722
7103
1.41
1.06
36.3
22.8
40.39
40.45
%
0.13
713
7032
722
7103
1.41
1.06
35.7
22.3
30.13
30.25
pg
0.99
713
7036
722
7103
1.41
1.06
35.8
22.4
4.47
4.50
e12/l
0.57
712
6961
722
7104
1.41
1.05
36.0
22.4
6.96
6.67
e9/l
3.11
711
6958
11
60
1.85
1.03
1.5
1.4
—
—
—
0
0
722
7106
1.40
1.03
36.3
22.5
133.75
135.20
g/l
1.72
713
7038
69
560
1.26
0.99
1.6
1.5
—
—
—
0
0
9
49
1.85
0.99
1.0
1.2
—
—
—
0
0
42
319
1.34
0.98
2.2
1.6
0.23
0.33
mg/l
1.02
24
139
664
6474
1.22
0.98
5.9
4.9
4.58
4.71
mmol/l
2.51
581
6077
54
426
1.29
0.97
1.4
1.3
40.80
32.01
au/ml
—
7
32
662
6456
1.21
0.95
5.8
4.8
1.43
1.49
mmol/l
2.83
581
6030
16
101
1.60
0.94
2.6
1.7
—
—
—
0
0
634
6161
1.19
0.94
4.6
4.1
1.41
1.27
mmol/l
4.18
556
5713
6
28
2.15
0.91
1.2
1.1
—
—
—
0
0
6
28
2.15
0.91
1.2
1.1
—
—
—
0
0
6
28
2.15
0.91
1.2
1.1
—
—
—
0
0
5
103
0.48
0.89
1.2
1.2
—
—
—
0
0
12
72
1.68
0.85
4.2
5.6
75.65
92.66
u/ml
—
6
27
37
286
1.31
0.80
2.1
1.7
—
—
—
0
0
0
24
0.00
0.79
0.0
3.5
—
—
—
0
0
0
26
0.00
0.78
0.0
2.0
—
1045.05
—
0
21
57
688
0.81
0.76
6.5
7.7
1.22
0.91
mmol/l
0.18
44
574
12
75
1.61
0.75
1.4
1.3
—
—
—
0
0
96
833
1.17
0.74
2.3
1.8
—
—
—
0
0
7
38
1.85
0.73
1.1
1.5
163.29
171.73
pmol/l
—
7
38
56
466
1.22
0.69
2.7
2.5
20.82
19.65
au/ml
—
6
46
86
748
1.17
0.66
2.5
2.6
5.17
7.32
umol/l
1.59
52
656
5
28
1.79
0.66
2.4
1.5
125.20
87.01
ng/l
—
5
28
11
70
1.58
0.65
1.0
1.1
—
—
—
0
0
59
696
0.83
0.65
6.3
7.8
7.41
7.42
ph
0.35
41
394
14
95
1.48
0.64
1.2
1.3
—
52.11
—
0
7
29
369
0.78
0.63
1.1
1.1
—
—
—
0
0
6
103
0.58
0.62
1.3
1.3
12.10
26.58
u/l
—
6
86
0
21
0.00
0.60
0.0
1.6
—
—
—
0
0
0
21
0.00
0.60
0.0
1.7
—
573.82
—
0
11
0
21
0.00
0.60
0.0
1.1
—
0.48
—
0
5
0
22
0.00
0.59
0.0
1.6
—
0.50
—
0
22
57
484
1.19
0.59
1.1
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
8.01
—
0
16
7
116
0.60
0.58
1.3
1.2
—
—
—
0
0
667
6561
1.15
0.56
6.2
5.6
2.69
2.76
mmol/l
1.33
588
6133
13
90
1.45
0.55
1.2
1.2
—
—
—
0
0
10
148
0.67
0.55
1.6
4.3
—
—
—
0
0
24
186
1.30
0.55
1.2
1.1
—
—
—
0
0
8
126
0.63
0.54
2.5
3.6
39.20
25.74
mg/l
—
8
88
6
38
1.58
0.54
1.0
1.2
9.50
9.74
mm/h
—
6
38
33
403
0.81
0.53
1.5
1.6
949.55
996.76
mu/l
0.14
26
332
26
209
1.25
0.47
1.5
1.3
—
—
—
0
0
13
94
1.39
0.46
1.5
1.2
—
—
—
0
0
5
82
0.61
0.46
1.4
1.3
—
—
—
0
0
37
311
1.20
0.45
2.1
1.7
—
—
—
0
0
37
311
1.20
0.45
2.1
1.7
—
—
—
0
0
10
69
1.46
0.44
1.3
1.5
30.10
33.67
g/l
—
10
64
37
312
1.20
0.44
2.2
1.7
—
—
—
0
0
5
31
1.62
0.43
1.2
1.7
—
—
—
0
0
8
59
1.36
0.41
1.4
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
4.4
—
6.27
—
0
18
11
80
1.38
0.38
1.4
1.1
—
—
—
0
0
17
213
0.79
0.37
2.5
1.7
—
—
—
0
0
9
71
1.27
0.36
1.1
1.1
—
—
—
0
0
6
42
1.43
0.35
1.0
1.1
—
—
—
0
0
21
172
1.23
0.34
1.3
1.2
—
—
—
0
0
15
118
1.28
0.33
1.0
1.1
—
—
—
0
0
7
100
0.70
0.30
6.0
6.0
449.00
362.54
umol/l
—
7
92
292
2821
1.06
0.30
1.9
2.1
95.23
96.77
pmol/l
0.22
154
1458
22
259
0.84
0.28
1.5
1.3
226.87
253.91
miu/ml
—
9
129
9
74
1.22
0.25
10.3
5.8
12.98
11.70
mg/l
—
9
69
158
1654
0.94
0.25
4.4
3.8
93.81
92.63
%
0.23
150
1618
35
312
1.13
0.24
2.1
1.7
—
—
—
0
0
28
248
1.13
0.22
2.2
1.8
20.95
20.44
s
0.25
22
227
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
7.3
—
5.08
—
0
10
0
10
0.00
0.21
0.0
2.5
—
—
—
0
0
0
12
0.00
0.21
0.0
3.3
—
36.50
—
0
12
0
12
0.00
0.21
0.0
6.7
—
8.58
—
0
12
0
12
0.00
0.21
0.0
2.3
—
1.17
—
0
12
0
12
0.00
0.21
0.0
1.0
—
58.67
—
0
12
0
13
0.00
0.21
0.0
2.0
—
2.38
—
0
13
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
18
155
1.17
0.20
1.4
1.2
—
—
—
0
0
6
78
0.77
0.15
2.8
2.3
—
—
—
0
0
315
3091
1.03
0.15
3.2
2.7
—
—
estimate
—
0
0
26
236
1.11
0.15
1.5
3.2
24.25
1200.31
u/ml
1.22
19
201
36
333
1.09
0.14
1.5
2.0
0.00
0.01
estimate
0.50
21
107
17
153
1.11
0.11
1.5
1.1
—
—
—
0
0
85
877
0.97
0.09
4.1
3.0
0.82
0.73
ug/l
0.58
65
530
38
400
0.95
0.09
1.7
1.7
—
—
—
0
0
6
58
1.03
0.08
1.0
1.2
—
—
—
0
0
5
65
0.77
0.08
1.2
2.8
—
—
—
0
0
6
71
0.84
0.07
2.2
1.1
—
—
—
0
0
6
73
0.82
0.07
1.5
1.3
—
—
—
0
0
11
122
0.90
0.07
1.5
1.5
—
—
—
0
0
8
92
0.87
0.06
1.4
1.4
—
—
—
0
0
8
92
0.87
0.06
1.4
1.4
—
—
—
0
0
8
92
0.87
0.06
1.4
1.4
—
—
—
0
0
8
92
0.87
0.06
1.4
1.4
—
—
—
0
0
31
296
1.05
0.06
1.1
1.1
—
—
—
0
0
20
212
0.94
0.05
1.2
1.2
—
—
—
0
0
16
151
1.06
0.03
1.1
1.1
1.06
2.81
u/ml
—
7
80
16
153
1.05
0.01
1.5
1.1
—
—
—
0
0
30
306
0.98
0.00
2.0
2.3
—
—
—
0
0
197
1968
1.00
0.00
1.9
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
37.80
—
0
5
0
5
0.00
0.00
0.0
1.0
—
73.46
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
6.4
—
0.16
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
64
0.94
-0.00
1.2
1.1
—
—
—
0
0
6
68
0.88
-0.00
1.0
1.1
—
—
u/ml
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
57
0.88
-0.00
1.0
1.1
—
1.20
nmol/l
—
0
6
6
60
1.00
-0.00
1.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint E4_ENDODISNAS and mortality.

Females

Parameter HR [95% CI] p-value
E4_ENDODISNAS 1.723 [1.5, 1.98] < 0.001
Birth year 0.997 [0.99, 1.01] 0.433

During the follow-up period (1.1.1998 — 31.12.2019), 435 out of 2137 females with E4_ENDODISNAS died.

Males

Parameter HR [95% CI] p-value
E4_ENDODISNAS 2.082 [1.77, 2.45] < 0.001
Birth year 0.992 [0.98, 1.0] 0.076

During the follow-up period (1.1.1998 — 31.12.2019), 361 out of 1294 males with E4_ENDODISNAS died.

Mortality risk

Mortality risk for people of age

years, who have E4_ENDODISNAS.

N-year risk Females Males
1 0.181% 0.487%
5 0.917% 2.933%
10 2.625% 6.936%
15 5.304% 12.736%
20 8.779% 21.356%

Relationships between endpoints

↥

Index endpoint: E4_ENDODISNAS – Endocrine disorders, other/unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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