Distal bite

K11_DISTAL_BITE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.20
  • Hospital discharge: ICD-10 K07.20
  • Cause of death: ICD-10 K07.20

3 out of 7 registries used, show all original rules.

1731

4. Check minimum number of events

None

1731

5. Include endpoints

None

1731

6. Filter based on genotype QC (FinnGen only)

1562

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 68300 33824 34461
Only index persons 55449 27655 27794
Unadjusted period prevalence (%)
Whole population 0.97 0.97 0.96
Only index persons 1.04 1.02 1.06
Median age at first event (years)
Whole population 10.38 10.43 10.32
Only index persons 11.12 11.17 11.07

-FinnGen-

Key figures

All Female Male
Number of individuals 1562 1087 475
Unadjusted period prevalence (%) 0.33 0.39 0.22
Median age at first event (years) 16.67 17.86 13.95

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1639
Matched controls
16262
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
18.3
307.7
334
224
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
81.2
307.7
220
31
K07.23
ICD-10 Finland
Deep bite
13.5
307.7
825
1135
K07.13
ICD-10 Finland
Retrognaty, mandibular
23.1
307.7
483
289
SBB10
NOMESCO Finland
Dental impressions
7.3
307.7
1017
2971
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
+∞
307.7
1639
*
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
6.4
281.4
653
1527
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
7.0
278.4
542
1068
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
6.3
277.9
662
1584
EB1MA
NOMESCO Finland
Cephalometry with X-ray
6.3
262.7
594
1346
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
6.9
257.8
500
975
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
6.5
251.8
524
1093
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
5.7
244.0
637
1631
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
5.7
226.4
556
1339
SJC10
NOMESCO Finland
Orthodontic band in one tooth
5.8
220.9
521
1208
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
5.9
209.7
477
1066
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
6.5
200.8
388
741
SAA04
NOMESCO Finland
Special examination of mouth
5.0
188.8
530
1408
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
7.0
176.2
301
504
SXC05
NOMESCO Finland
Other oral or dental procedure
4.3
172.7
659
2199
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
4.3
172.3
665
2237
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
4.1
138.7
493
1531
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.7
131.7
593
2157
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
4.0
130.7
484
1541
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
4.1
128.8
457
1410
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
4.6
118.2
332
856
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
3.7
113.0
467
1585
K07.24
ICD-10 Finland
Open bite
6.9
110.4
181
286
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
3.7
105.2
416
1365
OIKH, ,
NOMESCO Finland
3.8
103.3
385
1212
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
6.5
100.2
174
291
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
31.4
97.2
64
21
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.0
96.8
1069
6259
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
5.4
94.8
204
418
SAA03
NOMESCO Finland
Extended examination of mouth
3.3
93.1
1261
8183
OIKK, ,
NOMESCO Finland
3.3
91.8
461
1743
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
6.1
89.0
163
287
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
3.4
86.4
376
1298
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
3.8
79.1
282
851
K07.60
ICD-10 Finland
Snapping jaw
4.2
77.8
228
598
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.4
76.1
326
1107
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
10.9
74.9
82
78
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
34.5
68.7
44
13
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
4.8
67.1
163
368
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
33.7
66.7
43
13
EEC05
NOMESCO Finland
Le Fort I osteotomy
28.7
66.4
45
16
EBB10
NOMESCO Finland
Insertion of dental implant
11.7
65.3
68
60
SJB30
NOMESCO Finland
Extraoral traction arrangements and operation instruction, removable appliance
4.5
63.6
167
401
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
2.9
62.8
371
1504
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
6.9
61.8
98
148
EBB15
NOMESCO Finland
Insertion of dental implant abutment
18.2
61.6
50
28
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.9
61.4
339
1323
WZC00
NOMESCO Finland
Treatment plan or consultation
2.3
60.7
945
5976
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.9
57.6
181
496
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
3.1
52.9
251
895
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
12.8
44.9
44
35
K07.10
ICD-10 Finland
Asymmetry of jaw
11.4
44.6
47
42
SPC20
NOMESCO Finland
Implant borne crown
15.4
43.1
38
25
WZA90
NOMESCO Finland
Other medical or dental certificate
2.1
42.1
646
3889
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
15.6
38.9
34
22
OIKAL, ,
NOMESCO Finland
2.8
33.4
176
659
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
5.2
33.2
70
139
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.4
32.9
260
1186
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
32.1
569
3527
Z01.2
ICD-10 Finland
Dental examination
1.9
30.1
1119
8675
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
29.4
842
6013
EB1S1
NOMESCO Finland
Photography of teeth
5.0
29.1
63
128
SJC20
NOMESCO Finland
Extraoral traction appliance arrangement incl. patient instructions
3.8
28.9
89
239
SAA02
NOMESCO Finland
Basic examination of mouth
2.6
28.3
1491
12923
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
6.4
27.6
46
73
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
10.8
26.7
29
27
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
4.0
26.0
75
192
SXC03
NOMESCO Finland
Other oral or dental procedure
8.5
25.6
33
39
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
7.6
25.3
36
48
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
2.8
25.2
138
525
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
4.6
24.8
59
130
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
6.4
24.6
41
65
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
7.4
24.0
35
48
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
6.0
23.7
42
71
SAALT, ,
NOMESCO Finland
2.9
22.0
108
388
OIKKK, ,
NOMESCO Finland
5.1
21.2
45
90
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
23.5
19.9
28
12
EB1TW
NOMESCO Finland
3D modelling of dentition
7.8
19.4
27
35
SAA01
NOMESCO Finland
Simple examination of mouth
1.9
19.2
1366
11854
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
7.9
19.0
26
33
G50.1
ICD-10 Finland
Atypical facial pain
5.5
18.2
35
64
OIKJA, ,
NOMESCO Finland
3.4
18.2
66
198
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
16.0
17.0
27
17
K00.00
ICD-10 Finland
Hypodontia
2.6
16.9
97
378
OIKVA, ,
NOMESCO Finland
2.2
16.6
153
737
K07.33
ICD-10 Finland
Crowding of tooth or teeth
5.3
16.4
33
63
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
4.1
16.0
44
109
K03.00
ICD-10 Finland
Approximal wear
2.1
15.9
160
797
SDA03
NOMESCO Finland
Periodontal treatment
1.6
15.9
631
4665
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.5
15.6
689
5207
WYA10
NOMESCO Finland
Emergency care or similar visit
2.0
15.5
168
861
-1, ,
NOMESCO Finland
1.5
15.3
873
6963
EMAK, ,
NOMESCO Finland
3.0
14.7
67
231
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
4.3
14.7
38
90
EG1CG
NOMESCO Finland
Extensive MRI examination of mandibular joint with high intensity magnet
5.9
14.7
26
44
EDC30
NOMESCO Finland
Genioplasty
+∞
14.6
14
*
K07.61
ICD-10 Finland
Cracking jaw joint
2.7
14.1
75
281
OIKPU, ,
NOMESCO Finland
3.9
14.1
41
106
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
10.9
13.9
26
24
OIKRE, ,
NOMESCO Finland
3.1
13.9
58
190
EB1WA, ,
NOMESCO Finland
5.8
13.9
25
43
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
3.4
13.8
49
145
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
1.8
13.8
246
1479
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
3.3
13.6
52
162
G47.3
ICD-10 Finland
Sleep apnoea
1.8
13.5
214
1244
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
21.2
13.3
19
9
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.8
13.2
237
1428
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
20.0
12.4
18
9
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
5.2
12.4
25
48
OIKNV, ,
NOMESCO Finland
3.7
12.4
39
107
K03.66
ICD-10 Finland
Tooth plaque
1.7
12.2
256
1609
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
37.5
12.2
15
*
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
4.2
12.1
32
77
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.5
11.9
437
3134
K05.30
ICD-10 Finland
Periodontitis complex
1.9
11.6
141
752
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
2.8
11.6
59
217
SPAT1312
SPAT
General health counselling
1.4
11.5
698
5520
F45.8
ICD-10 Finland
Other somatoform disorders
1.9
11.4
139
741
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
5.0
11.4
24
48
M79.1
ICD-10 Finland
Myalgia
1.7
10.8
230
1448
SPF41
NOMESCO Finland
Repair of dental crown, bridge or implant structure, standard
5.0
10.4
22
44
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
2.1
10.4
97
470
EBA10
NOMESCO Finland
Operative extraction of tooth
1.5
10.3
350
2459
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
12.0
10.3
18
15
OIKAK, ,
NOMESCO Finland
4.7
10.1
23
49
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
5.3
10.0
20
38
QA9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head or neck, unspecified
10.6
9.7
18
17
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.3
9.6
73
325
D19
ICPC
Teeth/gum symptom/complaint
1.4
9.5
611
4839
SPC10
NOMESCO Finland
Standard dental crown
4.4
9.4
23
52
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
9.4
791
6546
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
4.1
9.3
25
61
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.5
9.2
339
2416
K05.31
ICD-10 Finland
Periodontitis pronounced
2.0
9.2
93
465
K07.4
ICD-10 Finland
Malocclusion, unspecified
2.6
8.9
52
206
K07.55
ICD-10 Finland
Malocclusion caused by tongue, lip and finger habits
4.5
8.7
21
47
SCD01
NOMESCO Finland
Removal of biofilm and supragingival calculus, short
2.6
8.7
49
190
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
14.0
8.6
14
10
G50.8
ICD-10 Finland
Other disorders of trigeminal nerve
14.0
8.6
14
10
OIKON, ,
NOMESCO Finland
2.8
8.6
43
157
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
3.1
8.3
34
111
EAB10
NOMESCO Finland
Excision and repair of frenum of lip
4.5
8.3
20
45
K06.00
ICD-10 Finland
Local gingivore traction
2.9
8.2
38
133
SFA10
NOMESCO Finland
One-surface restoration
1.4
8.2
996
8656
D82
ICPC
Teeth/gum disease
1.4
8.0
720
5969
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.0
8.0
82
413
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
7.9
1237
11160
K07.14
ICD-10 Finland
Retrognaty, maxillary
3.1
7.9
31
99
SPC08
NOMESCO Finland
Implant crown
8.4
7.8
16
19
ECA70
NOMESCO Finland
Regenerative periodontal surgery or gingival graft
10.8
7.8
14
13
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.5
7.7
267
1875
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
7.4
7.6
17
23
SPB20
NOMESCO Finland
Temporary bridge
11.8
7.5
13
11
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.4
7.5
49
205
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
3.5
7.5
25
72
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
2.6
7.4
42
164
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
79.8
7.4
8
*
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
13.3
7.3
12
9
SPE02
NOMESCO Finland
Metal-framed partial denture
4.4
7.3
18
41
EB3VA, ,
NOMESCO Finland
7.6
7.3
16
21
Z3229
NOMESCO Finland
Other healthcare associate professional
1.7
7.3
136
825
SCA01
NOMESCO Finland
Preventive oral health care, short
1.3
7.3
1016
8938
SCA02
NOMESCO Finland
Preventive oral health care
1.4
7.2
484
3820
OIKKE, ,
NOMESCO Finland
3.8
7.2
21
55
EBA00
NOMESCO Finland
Extraction of tooth
1.3
7.1
739
6221
YEA05
NOMESCO Finland
Excision of gingival or connective tissue for transplantation
29.9
7.1
9
*
J02AC01
ATC
fluconazole; systemic
1.4
7.1
437
3401
K07.2
ICD-10 Finland
Anomalies of dental arch relationship
20.0
7.1
10
5
SPE05
NOMESCO Finland
Demanding partial denture with metal framework
20.0
7.1
10
5
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
3.4
7.0
24
70
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
2.9
7.0
32
112
SPA02
NOMESCO Finland
Preparation for dental prosthetics
2.7
6.9
36
135
SJC04, ,
NOMESCO Finland
3.2
6.9
27
86
OIKTA, ,
NOMESCO Finland
3.0
6.8
29
97
OIKLI, ,
NOMESCO Finland
4.1
6.7
18
44
EDW99
NOMESCO Finland
Other operation on mandible
16.6
6.7
10
6
SPC25
NOMESCO Finland
Other demanding attachment of prosthodontic crown
22.4
6.6
9
*
ECA55
NOMESCO Finland
Complicated periodontal flap surgery
7.8
6.6
14
18
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
3.7
6.6
20
54
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.3
6.5
723
6117
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
6.5
372
2855
EB1MA, ,
SPAT
10.0
6.5
12
12
127
Kela drug reimbursment
Transplant complication
2.6
6.5
35
134
R06.5
ICD-10 Finland
Mouth breathing
1.7
6.4
123
753
SPA30
NOMESCO Finland
Grinding of a single crown and bridge pillar or a single post and crown
3.5
6.4
21
60
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
2.0
6.3
64
321
K07
ICD-10 Finland
Dentofacial anomalies [including malocclusion]
3.4
6.3
22
65
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.6
6.3
164
1082
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
8.1
6.3
13
16
G44.8
ICD-10 Finland
Other specified headache syndromes
2.6
6.3
35
136
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
6.3
429
3386
K08.0
ICD-10 Finland
Exfoliation of teeth due to systemic causes
+∞
6.2
6
*
XX2XX, ,
NOMESCO Finland
+∞
6.2
6
*
SPAT1263
SPAT
Sampling
1.3
6.2
638
5335
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
6.2
716
6083
SPA60
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 1 to 3 units
5.0
6.1
18
36
K03.1
ICD-10 Finland
Abrasion of teeth
3.1
6.1
25
82
K08.88
ICD-10 Finland
Other specified disorders of teeth and supporting structures
4.0
6.1
17
43
SPAT1324
SPAT
Screening procedure
1.5
6.1
206
1439
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
6.1
524
4275
SAE02, ,
NOMESCO Finland
2.5
6.0
36
145
K08.80
ICD-10 Finland
Toothache NOS
1.6
6.0
140
901

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
461
3516
1.42
8.73
4.9
3.4
0.00
0.01
estimate
1.34
150
1285
80
419
1.94
6.99
9.0
4.7
24.86
24.89
mmol/l
0.03
75
395
408
3148
1.38
6.99
3.2
2.8
35.25
67.23
ng/l
0.50
214
1517
248
1802
1.43
5.95
1.4
1.6
66505298.91
36335443.74
pmol/l
0.27
206
1588
127
801
1.62
5.92
3.2
2.4
0.14
0.30
e6/l
0.70
115
761
606
5061
1.30
5.86
4.3
3.0
0.04
0.02
estimate
0.32
130
1094
155
1037
1.53
5.62
4.9
4.6
0.56
0.55
%
0.02
50
291
24
86
2.80
5.07
4.3
2.7
-0.22
0.31
mmol/l
0.38
19
80
253
1895
1.38
5.07
4.6
3.9
1160.94
703.87
ng/l
0.46
200
1544
902
8018
1.26
4.96
3.9
3.3
69.70
68.46
ug/l
0.06
851
7671
24
90
2.67
4.68
2.6
2.2
—
—
—
0
0
415
3401
1.28
4.42
3.1
2.6
60.07
58.21
u/l
0.24
387
3190
102
659
1.57
4.36
11.0
6.9
133.20
130.88
g/l
0.55
97
637
243
1853
1.35
4.34
11.2
6.9
0.81
0.82
mmol/l
0.23
230
1787
419
3459
1.27
4.18
6.1
4.6
—
—
—
0
0
293
2312
1.31
4.14
1.3
1.3
17.25
24.18
iu/ml
1.14
79
607
275
2151
1.32
4.14
1.3
1.3
3.69
9.84
u/ml
2.43
108
799
271
2122
1.32
4.04
3.9
3.2
310.47
313.86
umol/l
0.23
252
1953
152
1087
1.43
3.99
5.1
4.9
0.47
0.79
%
1.02
45
311
413
3421
1.26
3.99
4.0
3.0
1.02
2.49
kg/l
1.08
256
2078
146
1038
1.43
3.96
5.2
5.0
0.08
0.10
%
0.14
40
260
86
548
1.59
3.93
1.6
2.1
5.00
8.15
ug/l
1.48
75
474
81
513
1.60
3.80
1.4
1.2
0.41
1.36
u/ml
—
10
23
88
571
1.56
3.73
7.4
7.0
0.63
0.63
%
0.06
88
571
70
433
1.63
3.63
1.2
1.2
—
—
—
0
0
137
982
1.42
3.57
2.7
3.4
4.80
4.84
pmol/l
0.15
129
904
147
1068
1.40
3.55
5.6
5.2
0.00
0.06
%
1.50
39
253
460
3903
1.24
3.54
7.6
7.1
1.10
1.12
inr
0.29
389
3236
30
143
2.10
3.53
3.4
3.0
6.75
6.67
mmol/l
0.06
30
137
258
2047
1.30
3.49
1.6
1.5
411.20
530.15
titre
0.91
50
390
203
1566
1.33
3.36
2.5
3.0
3.73
5.11
e9/l
2.42
180
1401
152
1126
1.37
3.29
1.6
1.6
1265.17
1155.14
nmol/l
0.80
105
889
614
5396
1.21
3.28
3.3
2.9
—
—
estimate
—
0
0
55
330
1.68
3.23
1.6
1.7
—
23.20
—
0
5
36
191
1.89
3.18
10.7
4.8
5.24
6.99
pmol/l
1.40
36
191
930
8515
1.19
3.11
4.2
3.5
36.25
33.35
u/l
0.27
885
8170
767
6909
1.19
3.07
4.7
3.4
0.00
0.01
estimate
1.32
155
1297
764
6885
1.19
3.03
4.7
3.4
0.01
1.14
estimate
0.49
156
1326
337
2813
1.24
2.97
2.6
2.3
164.01
215.45
u/l
1.10
319
2703
80
537
1.50
2.97
2.3
2.0
0.00
0.01
estimate
0.80
30
200
754
6811
1.18
2.85
4.7
3.3
0.00
0.00
estimate
0.50
157
1333
45
266
1.70
2.83
6.5
4.1
—
—
—
0
0
680
6097
1.18
2.79
3.9
3.0
73.76
69.80
nmol/l
3.30
637
5742
153
1173
1.32
2.68
1.6
1.4
—
—
—
0
0
12
42
2.85
2.52
2.8
2.5
99.66
107.19
ng/l
0.08
12
42
33
185
1.79
2.52
5.0
2.9
1.27
1.31
mmol/l
0.15
33
179
414
3585
1.20
2.49
3.1
2.4
—
—
—
0
0
762
6946
1.17
2.45
7.3
5.5
6.12
6.23
mmol/l
0.70
708
6466
117
875
1.35
2.44
1.3
1.2
64.95
31.32
au/ml
—
6
42
44
271
1.63
2.41
3.0
3.7
3.00
3.76
e9/l
2.65
44
271
247
2043
1.23
2.37
14.0
8.4
1.20
1.19
mmol/l
0.26
232
1940
217
1770
1.25
2.36
3.9
4.1
29.37
29.84
s
0.72
208
1740
323
2753
1.20
2.30
4.3
2.9
7.87
7.98
e6/l
0.04
296
2480
522
4640
1.17
2.29
3.0
2.4
—
—
—
0
0
27
147
1.84
2.28
1.2
1.2
45.29
33.09
mg/l
0.43
22
119
43
268
1.61
2.27
7.4
6.8
—
—
—
0
0
35
208
1.68
2.22
1.7
1.3
—
—
—
0
0
311
2651
1.20
2.21
2.6
2.6
0.92
1.16
mg/l
0.82
230
1923
22
113
1.94
2.21
2.5
1.9
—
—
—
0
0
15
66
2.27
2.21
3.6
3.3
—
—
—
0
0
438
3849
1.18
2.20
3.9
2.7
0.04
0.02
estimate
0.26
129
1094
6
14
4.26
2.13
4.0
2.9
4.47
4.24
mmol/l
—
6
14
23
122
1.88
2.12
2.1
1.5
—
—
—
0
0
1430
13785
1.23
2.09
14.1
11.5
20.73
21.47
mg/l
0.36
1115
10352
423
3722
1.17
2.08
3.1
2.8
2.60
2.58
mg/l
0.06
373
3308
35
212
1.65
2.08
10.8
4.4
1.59
2.03
mmol/l
0.58
20
126
133
1040
1.29
2.07
2.2
1.9
0.00
0.03
estimate
1.05
35
244
1574
15365
1.41
2.02
20.5
17.4
6.62
6.64
e9/l
0.18
1532
14899
124
964
1.30
2.02
2.4
2.3
22.35
14.90
au/ml
0.49
16
93
614
5568
1.15
2.02
6.6
6.3
11.52
11.82
umol/l
0.15
577
5227
1574
15366
1.41
2.01
20.8
17.5
135.10
135.12
g/l
0.03
1559
15200
104
790
1.33
2.00
1.2
1.2
—
—
—
0
0
1573
15356
1.41
2.00
20.4
17.3
29.74
29.61
pg
2.35
1557
15189
1573
15356
1.41
2.00
20.5
17.3
4.56
4.58
e12/l
1.43
1530
14902
1573
15357
1.40
1.98
21.1
17.9
40.26
40.52
%
0.52
1558
15183
1572
15346
1.40
1.98
20.5
17.4
264.79
265.56
e9/l
0.19
1531
14928
1432
13820
1.22
1.98
15.2
12.6
66.53
66.28
umol/l
0.17
1410
13653
188
2239
0.81
1.97
4.5
3.2
3.59
3.79
e6/l
0.08
108
1056
1572
15348
1.40
1.96
20.4
17.3
88.76
88.50
fl
1.42
1556
15181
1058
9973
1.15
1.95
4.0
3.4
1.15
1.18
mmol/l
0.78
997
9454
136
1076
1.28
1.94
2.3
2.3
11.19
9.96
nmol/l
0.82
123
988
625
5687
1.15
1.94
4.1
3.1
6.39
6.25
ph
2.56
361
3023
9
33
2.72
1.91
5.6
2.1
—
—
—
0
0
24
134
1.79
1.91
1.0
1.2
—
—
—
0
0
168
1368
1.24
1.89
1.3
1.3
—
—
—
0
0
69
496
1.40
1.89
3.1
1.9
99.00
114.93
au/ml
0.40
21
161
220
1843
1.21
1.89
1.7
1.8
—
—
—
0
0
221
1853
1.21
1.88
1.7
1.8
—
—
—
0
0
295
2541
1.19
1.87
3.9
4.1
—
—
—
0
0
12
52
2.30
1.84
3.8
3.1
—
—
—
0
0
199
1655
1.22
1.84
3.0
2.3
326.21
376.19
nmol/l
3.49
187
1576
218
1832
1.21
1.82
1.7
1.8
—
—
—
0
0
1456
14099
1.22
1.79
11.6
9.3
—
—
—
0
0
849
7916
1.13
1.77
9.5
7.6
2.05
2.08
e9/l
0.48
777
6967
416
3700
1.15
1.76
3.2
2.6
—
—
—
0
0
223
1884
1.20
1.76
4.1
2.6
2.53
2.53
g/l
0.04
208
1768
831
7741
1.13
1.75
9.6
7.6
0.54
0.54
e9/l
0.14
754
6630
61
437
1.40
1.72
2.9
2.2
—
—
—
0
0
177
2087
0.82
1.69
1.2
1.3
—
—
—
0
0
205
1726
1.20
1.68
1.7
1.8
—
—
—
0
0
89
680
1.32
1.68
2.8
1.6
195.05
188.29
u/ml
0.06
46
342
242
2069
1.19
1.68
4.0
2.7
14.93
14.24
umol/l
0.76
226
1964
1416
13693
1.19
1.66
11.4
9.7
24.58
25.20
u/l
0.47
1373
13360
15
75
1.99
1.66
1.6
2.4
1.22
1.20
mmol/l
1.01
15
75
454
4080
1.14
1.65
2.0
1.9
—
—
—
0
0
44
300
1.47
1.63
1.4
1.4
28.01
16.32
u/l
1.07
32
260
216
1835
1.19
1.62
1.7
1.8
—
—
—
0
0
15
76
1.97
1.61
1.6
2.4
106.27
105.75
mmol/l
0.19
15
76
70
520
1.35
1.61
3.0
1.8
—
—
—
0
0
328
2886
1.16
1.60
3.3
2.6
—
—
—
0
0
28
173
1.62
1.60
4.7
3.0
—
—
—
0
0
828
7744
1.12
1.57
9.6
7.6
0.04
0.04
e9/l
0.15
750
6630
6
20
2.98
1.57
1.0
1.3
60.83
63.35
ug/l
—
6
20
426
3826
1.14
1.56
4.4
3.8
8.19
8.77
mmol/l
1.34
386
3471
57
413
1.38
1.54
1.4
1.2
7.51
17.72
u/ml
—
8
52
202
1715
1.19
1.53
4.3
2.8
23.63
22.59
%
0.53
190
1630
39
264
1.48
1.51
1.4
1.7
—
3017.14
—
0
7
15
78
1.92
1.51
1.6
2.4
4.07
3.96
mmol/l
0.67
15
78
1137
10854
1.13
1.48
4.4
3.9
4.61
4.57
mmol/l
0.69
1083
10373
851
7997
1.12
1.44
10.0
8.0
0.18
0.19
e9/l
0.79
773
6983
95
1174
0.79
1.44
1.9
2.4
40.14
32.53
u/l
0.59
80
981
5
16
3.11
1.42
1.0
1.3
201.20
297.63
umol/24h
—
5
16
123
1004
1.23
1.41
4.9
4.4
60.19
68.56
e9/l
1.94
95
669
27
172
1.57
1.39
4.3
4.1
—
—
—
0
0
926
8754
1.11
1.38
5.5
4.1
—
2.21
—
0
10
20
118
1.69
1.38
1.8
2.0
31.60
32.37
pg
0.40
20
118
20
118
1.69
1.38
7.5
4.0
0.45
0.68
index
0.85
20
118
55
405
1.36
1.37
1.2
1.2
—
—
—
0
0
89
702
1.27
1.37
4.0
4.8
21.60
21.65
s
0.03
82
651
11
53
2.07
1.36
1.5
1.2
—
—
—
0
0
155
1301
1.20
1.35
9.8
9.3
105.61
105.06
mmol/l
0.83
155
1301
644
5980
1.11
1.33
12.7
8.2
1.22
1.22
mmol/l
1.81
580
5401
166
1406
1.19
1.32
7.1
5.5
1.47
1.53
%
0.30
153
1307
79
618
1.28
1.31
1.8
2.0
3.89
6.83
iu/ml
0.92
20
119
20
120
1.66
1.31
1.5
1.2
—
—
—
0
0
178
1519
1.18
1.30
1.3
1.4
178.72
354.45
u/ml
1.92
169
1408
89
708
1.26
1.29
9.0
3.6
1.24
1.23
mmol/l
0.69
81
619
125
1036
1.21
1.26
4.7
3.4
—
—
—
0
0
189
1627
1.17
1.25
2.0
1.6
—
—
—
0
0
77
606
1.27
1.23
3.2
2.7
66.05
67.15
g/l
0.58
72
578
887
8398
1.10
1.23
11.2
9.7
3.64
3.74
e9/l
0.82
811
7157
1048
10007
1.11
1.22
4.8
4.4
36.20
36.85
mmol/mol
1.93
988
9534
1121
10745
1.11
1.21
4.3
3.8
1.47
1.46
mmol/l
0.52
1056
10197
311
2784
1.13
1.20
3.5
3.2
114.89
95.94
ug/g
0.32
263
2216
183
1577
1.17
1.20
16.3
6.0
5.04
5.07
kpa
0.28
178
1524
773
7275
1.10
1.20
9.7
7.7
8.53
8.42
%
0.55
737
6886
1241
12643
0.89
1.19
17.3
14.8
13.14
13.19
%
1.07
1219
12433
215
1878
1.16
1.19
13.6
7.3
7.37
7.37
ph
0.63
153
1277
1130
10843
1.11
1.17
4.6
4.1
2.75
2.72
mmol/l
0.34
1066
10306
71
557
1.28
1.17
3.6
3.7
139.66
126.09
ng/l
0.10
65
493
72
566
1.27
1.17
10.8
6.3
227.51
442.07
mg/l
1.55
51
358
360
3258
1.12
1.16
4.4
3.3
—
0.33
—
0
9
177
1526
1.17
1.16
2.1
1.5
—
—
—
0
0
332
2992
1.13
1.15
1.7
1.9
—
—
—
0
0
173
1491
1.17
1.14
1.3
1.3
140.88
147.16
u/ml
0.07
68
522
10
50
1.99
1.14
1.1
1.1
—
—
—
0
0
10
50
1.99
1.14
1.8
2.5
—
—
—
0
0
10
50
1.99
1.14
1.1
1.1
—
—
—
0
0
211
1848
1.15
1.13
13.3
7.3
1.55
1.44
mmol/l
0.20
179
1535
1328
12870
1.13
1.11
16.0
12.3
3.91
3.90
mmol/l
0.58
1286
12539
793
7495
1.10
1.10
9.6
7.6
32.37
31.97
%
0.51
763
7174
7
31
2.25
1.10
1.0
1.5
—
10.13
%
—
0
8
10
51
1.95
1.09
1.0
1.3
52.20
68.90
ug/l
—
10
51
20
127
1.57
1.08
1.5
1.2
0.97
0.65
ratio
0.66
11
71
118
1378
0.84
1.08
1.6
1.5
—
—
—
0
0
1169
11258
1.11
1.07
4.6
4.2
14.47
14.40
pmol/l
0.48
1062
10257
7
32
2.18
1.07
1.1
2.2
0.63
0.61
mmol/l
—
7
32
180
1566
1.16
1.06
16.5
6.0
7.41
7.41
ph
1.43
148
1306
312
2816
1.12
1.06
1.6
1.5
20.89
19.28
nmol/l
1.20
267
2505
38
277
1.37
1.06
1.2
1.1
4.50
5.28
iu/ml
—
5
59
57
442
1.29
1.05
3.1
3.1
50.85
55.58
%
2.02
57
442
1301
12605
1.12
1.05
5.4
4.9
1.85
1.87
mu/l
0.23
1230
12014
767
7250
1.09
1.04
9.7
7.7
2.94
2.92
%
0.08
729
6871
765
7234
1.09
1.03
9.8
7.7
0.66
0.66
%
0.10
728
6852
12
67
1.78
1.02
1.3
1.2
—
—
—
0
0
12
67
1.78
1.02
4.3
4.6
3.70
4.00
%
—
6
28
1325
12856
1.12
1.02
16.0
12.2
139.64
139.64
mmol/l
0.05
1287
12579
9
47
1.90
1.01
1.3
1.3
135.56
151.26
nmol/l
—
9
47
16
98
1.63
1.00
1.5
1.3
—
—
—
0
0
776
7350
1.09
0.99
9.4
7.5
53.11
53.45
%
0.37
754
7088
19
122
1.55
0.99
1.2
1.2
121.89
121.26
pmol/l
0.02
19
122
168
1463
1.16
0.99
1.9
2.0
—
—
—
0
0
928
8860
1.09
0.99
8.0
6.9
88.86
87.91
u/l
0.17
886
8432
32
231
1.38
0.96
4.7
3.5
163.47
186.44
e6/l
0.33
32
176
9
50
1.79
0.96
1.1
1.1
—
—
—
0
0
1123
10822
1.09
0.95
3.8
3.5
5.51
5.55
mmol/l
0.56
1044
10122
153
1329
1.16
0.94
4.3
3.5
9.44
10.13
g/l
1.68
147
1257
9
51
1.75
0.93
2.7
1.9
—
—
—
0
0
31
224
1.38
0.93
4.5
3.5
413.87
545.27
e6/l
1.46
31
166
15
93
1.61
0.91
1.6
1.9
0.96
0.87
%
—
5
52
15
93
1.61
0.91
2.1
1.6
—
—
—
0
0
341
3123
1.11
0.90
5.5
3.8
7.39
7.39
ph
0.35
248
2141
10
55
1.81
0.90
1.8
2.4
—
—
—
0
0
171
1505
1.14
0.89
1.7
1.8
—
—
—
0
0
14
86
1.62
0.88
1.2
1.8
42.83
48.33
%
—
6
63
47
366
1.28
0.87
2.9
2.6
183.88
287.96
ug/l
1.65
40
335
144
1256
1.15
0.86
1.5
1.5
3.05
3.29
mmol/l
1.62
79
809
90
756
1.19
0.85
4.1
4.0
7.36
7.35
ph
0.45
71
564
877
8388
1.08
0.84
5.1
3.9
149.94
901.60
e6/l
0.91
16
106
22
153
1.43
0.83
1.5
1.7
—
—
—
0
0
186
1656
1.13
0.82
15.6
10.5
—
—
—
0
0
34
256
1.32
0.81
4.2
3.5
1056.79
1372.24
e6/l
1.68
34
201
490
4590
1.08
0.79
2.1
2.2
—
—
—
0
0
36
275
1.31
0.79
1.3
1.2
—
—
—
0
0
87
735
1.18
0.78
1.0
1.1
—
—
—
0
0
10
58
1.72
0.78
1.2
1.8
63.20
38.50
%
—
5
42
0
27
0.00
0.77
0.0
1.7
—
—
—
0
0
22
156
1.40
0.76
1.0
1.0
—
—
—
0
0
213
2317
0.90
0.75
4.1
3.1
0.56
1.01
e6/l
4.84
133
1136
138
1214
1.14
0.75
16.5
6.4
9.91
9.70
kpa
0.83
133
1175
22
158
1.39
0.72
1.5
1.4
—
—
—
0
0
56
459
1.22
0.71
1.1
1.1
—
—
—
0
0
246
2247
1.10
0.71
1.6
1.6
—
—
—
0
0
400
3736
1.08
0.70
3.2
3.0
2.37
2.37
mmol/l
0.56
368
3499
46
370
1.24
0.69
1.3
1.2
—
—
—
0
0
466
4380
1.08
0.69
1.8
1.8
95.55
97.62
pmol/l
0.46
250
2336
66
552
1.19
0.69
1.1
1.1
25.92
19.69
au/ml
—
9
109
7
42
1.66
0.68
1.0
1.2
27.86
27.50
s
—
7
42
7
42
1.66
0.68
6.6
4.4
5.69
5.05
kpa
—
7
42
556
5269
1.07
0.66
9.4
7.9
—
—
—
0
0
39
478
0.80
0.65
1.2
1.3
—
—
—
0
0
78
668
1.17
0.63
1.1
1.1
8.21
5.94
u/ml
0.47
50
409
11
70
1.56
0.63
1.3
1.1
—
—
—
0
0
23
171
1.34
0.63
1.5
1.2
—
—
—
0
0
24
180
1.33
0.62
1.5
1.2
—
—
—
0
0
491
4645
1.07
0.61
8.2
6.0
37.56
37.73
g/l
0.32
461
4423
163
1471
1.11
0.61
1.7
1.6
—
—
—
0
0
5
30
1.66
0.61
3.2
4.7
17.14
16.78
%
—
5
30
5
30
1.66
0.61
1.0
1.8
340.64
301.98
mu/l
—
5
30
55
459
1.20
0.60
1.1
1.1
—
—
—
0
0
268
2479
1.09
0.60
4.3
2.9
558.58
572.67
mosm/kgh2o
0.34
242
2182
11
71
1.54
0.60
1.1
1.0
—
—
—
0
0
27
208
1.29
0.59
2.5
2.7
—
—
—
0
0
8
52
1.53
0.59
2.3
3.4
—
—
—
0
0
142
1275
1.11
0.59
15.9
6.3
—
—
—
0
0
33
262
1.25
0.58
1.2
1.1
—
—
—
0
0
49
407
1.20
0.57
3.0
2.7
28.35
13.59
e6/l
0.34
37
301
30
236
1.27
0.57
1.1
1.1
—
—
—
0
0
10
64
1.55
0.57
2.0
2.4
28.14
16.56
mg/l
—
5
48
34
272
1.25
0.56
3.1
1.8
—
—
—
0
0
6
36
1.66
0.56
1.7
1.9
—
—
—
0
0
6
36
1.66
0.56
1.2
1.2
—
—
—
0
0
723
6943
1.06
0.55
13.4
10.3
0.00
0.00
e9/l
0.29
625
5509
46
382
1.20
0.55
3.2
2.8
—
—
—
0
0
110
980
1.12
0.53
11.0
6.0
65.76
61.37
ng/l
0.40
104
932
49
411
1.19
0.53
3.1
2.7
115.34
135.21
e6/l
0.10
38
317
151
1370
1.10
0.53
4.6
3.8
0.22
0.22
g/l
0.25
146
1304
9
62
1.44
0.52
2.4
2.6
—
—
—
0
0
12
82
1.46
0.52
1.1
1.1
232.47
217.74
iu/ml
0.07
12
82
6
39
1.53
0.52
1.0
1.3
—
—
—
0
0
6
39
1.53
0.52
2.7
2.9
0.75
0.79
nmol/l
—
6
30
24
302
0.79
0.52
1.0
1.3
0.51
3.85
u/ml
—
8
180
9
63
1.42
0.52
2.7
4.4
230.89
135.29
ug/l
—
9
63
31
249
1.24
0.51
2.5
3.1
22.48
26.93
mg/l
0.30
18
169
16
117
1.36
0.50
1.1
1.6
4.76
5.85
ug/l
1.04
16
104
71
618
1.15
0.50
1.0
1.1
9.41
9.19
u/ml
0.03
37
354
14
100
1.39
0.50
1.2
1.1
27.09
35.90
iu/ml
0.48
14
100
20
152
1.31
0.50
1.1
1.2
—
—
—
0
0
142
1294
1.10
0.47
1.2
1.2
—
—
—
0
0
176
1620
1.09
0.47
2.9
2.2
7240.79
7747.02
u/l
0.06
54
499
23
286
0.80
0.47
1.0
1.4
0.91
17.11
u/ml
—
9
154
162
1486
1.09
0.47
6.3
4.3
6.97
6.73
umol/l
0.06
141
1268
56
482
1.16
0.46
3.4
2.5
1.02
1.02
ratio
0.80
51
433
137
1248
1.10
0.46
14.5
6.2
24.57
24.22
mmol/l
1.09
137
1234
14
102
1.36
0.45
1.2
1.2
—
—
—
0
0
468
4464
1.06
0.45
1.6
1.6
—
—
—
0
0
33
272
1.21
0.44
3.2
1.8
—
—
—
0
0
130
1184
1.10
0.44
1.9
1.8
—
—
—
0
0
41
346
1.18
0.44
1.4
1.4
356.54
329.19
ug/g
0.40
16
183
33
273
1.20
0.43
3.2
1.8
—
—
—
0
0
33
273
1.20
0.43
3.2
1.8
—
—
—
0
0
173
1600
1.08
0.42
1.7
1.7
3.39
3.33
ratio
0.19
113
1127
48
412
1.16
0.42
3.7
3.4
6.01
7.03
umol/l
0.39
36
333
5
32
1.55
0.42
1.0
1.2
—
—
—
0
0
8
57
1.39
0.42
1.3
1.0
—
—
—
0
0
14
104
1.34
0.41
2.3
2.1
—
—
—
0
0
14
104
1.34
0.41
1.6
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
72.00
—
0
16
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
5
33
1.50
0.41
1.0
1.0
—
—
—
0
0
5
33
1.50
0.41
1.0
1.0
—
—
—
0
0
5
33
1.50
0.41
1.0
1.0
—
—
—
0
0
10
70
1.42
0.40
4.2
2.5
172.00
166.84
ug/g
—
10
63
111
1199
0.91
0.40
2.3
2.1
—
—
—
0
0
468
4480
1.05
0.40
2.0
1.9
1.39
1.29
mmol/l
0.92
397
4005
30
249
1.20
0.39
1.1
1.1
6.16
16.28
u/ml
—
5
84
5
35
1.42
0.39
2.8
1.3
—
—
—
0
0
19
235
0.80
0.39
1.0
1.1
0.27
2.28
u/ml
—
6
123
0
19
0.00
0.39
0.0
1.0
—
0.15
—
0
6
37
314
1.17
0.38
1.2
1.6
314.07
368.15
mu/l
0.90
28
262
114
1042
1.09
0.38
2.1
2.0
7.23
7.06
u/l
0.06
93
753
9
67
1.33
0.38
1.1
1.1
448.89
420.63
nmol/l
—
9
62
15
115
1.30
0.37
4.2
5.9
366.86
195.82
umol/l
—
7
77
8
114
0.69
0.37
2.8
2.9
40.82
56.20
umol/l
—
8
108
20
244
0.81
0.37
1.1
1.3
—
—
—
0
0
14
107
1.30
0.35
1.5
1.7
—
—
—
0
0
97
884
1.09
0.35
1.1
1.2
8.95
7.41
u/ml
0.32
59
596
53
467
1.13
0.35
1.4
1.3
—
—
—
0
0
62
552
1.12
0.34
1.0
1.1
3.21
0.57
u/ml
0.38
24
214
64
571
1.12
0.34
1.1
1.1
16.60
6.81
eliau/ml
0.27
12
73
163
1719
0.93
0.34
2.0
2.3
2.41
2.42
mmol/l
0.63
152
1526
12
90
1.33
0.34
1.5
1.5
1.31
1.27
nmol/l
0.04
12
83
10
73
1.36
0.33
2.4
4.5
—
—
—
0
0
10
73
1.36
0.33
1.0
1.2
187.24
187.49
pmol/l
—
10
73
85
773
1.10
0.33
1.8
1.5
—
—
—
0
0
127
1349
0.93
0.33
1.5
1.4
—
—
—
0
0
6
46
1.30
0.32
1.5
2.7
9.17
9.37
%
—
6
46
14
175
0.79
0.32
2.2
2.5
0.52
4.19
u/ml
—
7
64
79
718
1.10
0.31
1.7
1.6
—
—
—
0
0
73
661
1.10
0.31
2.8
2.7
0.73
0.70
ug/l
0.18
35
368
94
862
1.09
0.31
1.1
1.2
2.21
1.51
u/ml
0.23
47
515
249
2363
1.05
0.31
4.0
4.3
7.03
8.35
mg/mmol
0.19
153
1612
10
130
0.76
0.31
1.0
1.0
—
—
—
0
0
7
99
0.70
0.30
1.3
1.6
—
—
—
0
0
348
3332
1.05
0.30
1.8
1.7
—
—
—
0
0
135
1258
1.07
0.30
1.6
1.6
1294.99
977.98
mu/l
0.87
120
1107
13
101
1.28
0.30
1.0
1.1
1513.77
1454.81
miu/ml
0.08
13
101
113
1047
1.08
0.29
2.1
2.0
1.15
1.22
g/l
0.37
108
991
7
55
1.26
0.29
2.0
1.6
13.00
13.57
pmol/l
—
7
48
18
147
1.22
0.29
1.0
1.2
—
—
—
0
0
105
973
1.08
0.28
1.2
1.2
5.60
3.38
u/ml
0.47
57
614
16
130
1.22
0.27
1.0
1.0
11.93
18.92
u/ml
—
8
85
40
443
0.89
0.26
1.6
1.5
4.62
5.10
ug/l
0.18
34
412
53
577
0.91
0.25
2.6
4.2
3.41
14.81
ug/l
0.77
35
425
245
2340
1.05
0.25
3.3
3.8
57.91
58.51
mg/l
0.01
150
1647
496
4805
1.03
0.25
1.5
1.6
1.89
1.86
g/l
0.23
320
2839
30
263
1.13
0.23
1.2
1.1
—
—
—
0
0
21
179
1.17
0.23
2.1
2.4
—
—
—
0
0
27
236
1.14
0.22
3.5
5.8
417.19
401.36
umol/l
0.20
27
217
141
1334
1.05
0.22
1.9
2.2
—
—
—
0
0
35
312
1.12
0.22
1.1
1.2
18.44
208.49
iu/ml
—
8
90
187
1783
1.05
0.21
3.3
3.3
415.92
740.23
ng/l
1.07
98
978
44
478
0.91
0.21
1.6
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
29.90
—
0
10
5
42
1.18
0.21
3.2
3.6
12.80
7.57
mmol/l
—
5
42
5
42
1.18
0.21
6.2
6.2
—
—
—
0
0
48
518
0.92
0.21
1.1
1.1
—
—
—
0
0
42
456
0.91
0.20
1.6
1.5
1.38
1.26
mm
0.65
31
327
6
48
1.24
0.20
1.0
1.1
—
—
—
0
0
6
49
1.22
0.20
1.5
2.6
34.17
28.82
%
—
6
49
122
1154
1.05
0.20
1.6
1.7
340.59
343.33
mu/l
0.03
107
1064
553
5389
1.03
0.19
14.9
8.4
1.22
1.22
mmol/l
0.35
526
5105
429
4166
1.03
0.19
5.2
3.5
50.71
44.08
e6/l
0.07
352
3079
6
51
1.17
0.19
1.0
1.3
—
—
—
0
0
330
3192
1.03
0.19
6.5
5.3
89.33
90.73
%
0.59
320
3127
118
1117
1.05
0.19
5.1
4.3
1.74
1.66
ug/l
0.14
109
1008
19
164
1.15
0.19
1.8
1.5
—
9.97
—
0
6
45
484
0.92
0.18
1.7
1.6
—
—
—
0
0
39
354
1.10
0.18
5.1
3.2
4.43
5.81
index
0.41
28
203
444
4317
1.03
0.18
4.5
3.6
28.72
29.80
u/l
0.35
431
4138
42
383
1.09
0.18
1.9
2.1
—
—
—
0
0
15
127
1.17
0.18
1.3
1.2
—
—
nmol/l
—
0
0
92
866
1.06
0.18
1.1
1.2
2.70
3.59
u/ml
0.39
57
565
13
152
0.85
0.18
1.2
1.1
—
—
—
0
0
77
807
0.94
0.17
1.9
1.6
0.22
0.23
mg/l
0.02
36
324
8
67
1.19
0.16
5.4
3.1
183.13
166.94
e6/l
—
8
67
365
3698
0.97
0.16
5.0
3.5
0.42
0.27
e6/l
0.34
282
2632
8
71
1.12
0.16
1.0
1.1
—
46.33
—
0
6
12
101
1.18
0.15
1.2
3.1
1751.75
755.07
u/ml
0.81
12
101
13
111
1.16
0.14
2.3
4.1
10.43
266.85
u/ml
—
7
102
80
832
0.95
0.14
1.3
1.3
257.57
230.83
miu/ml
0.21
39
402
23
206
1.11
0.14
1.0
1.2
—
—
—
0
0
15
169
0.88
0.14
1.8
2.2
—
—
—
0
0
24
216
1.10
0.14
1.6
1.4
—
—
—
0
0
102
973
1.04
0.13
2.4
2.0
6.33
6.22
ph
0.63
69
609
98
935
1.04
0.13
1.2
1.2
—
—
—
0
0
135
1298
1.03
0.12
2.1
1.9
15.79
16.75
iu/l
0.15
113
1000
34
362
0.93
0.12
4.0
6.0
—
—
—
0
0
24
218
1.09
0.12
1.6
1.4
0.27
0.37
g/l
1.73
19
172
60
625
0.95
0.12
1.6
1.5
60.92
63.01
ug/l
0.12
53
532
13
113
1.14
0.12
1.8
2.1
—
—
—
0
0
22
199
1.10
0.12
1.0
1.2
8.12
21.19
u/ml
0.47
12
150
56
529
1.05
0.11
1.0
1.1
0.64
0.68
ratio
—
5
40
20
182
1.09
0.09
1.2
1.3
29.51
17.85
u/ml
0.22
14
141
47
445
1.05
0.09
1.8
2.0
2.72
4.19
iu/l
1.50
18
188
45
468
0.95
0.09
1.3
1.6
0.19
0.30
nmol/l
3.18
40
377
47
488
0.95
0.09
1.7
1.7
—
—
—
0
0
5
61
0.81
0.08
2.4
1.4
88.80
88.15
nmol/24h
—
5
61
7
63
1.10
0.08
1.1
1.2
—
3.13
u/ml
—
0
8
17
155
1.09
0.07
2.0
4.1
54.14
131.15
u/ml
—
5
48
12
132
0.90
0.07
1.3
1.1
—
—
—
0
0
53
506
1.04
0.07
1.7
1.6
8.22
6.50
u/ml
—
9
125
8
77
1.03
0.07
1.4
1.1
—
—
—
0
0
8
91
0.87
0.06
1.6
1.1
—
—
—
0
0
16
171
0.93
0.06
1.4
1.4
90.00
267.27
titre
—
6
33
20
186
1.07
0.06
17.3
13.1
12.39
11.27
%
0.81
20
186
1305
12979
0.99
0.06
16.6
14.6
334.26
333.59
g/l
1.86
1293
12874
39
372
1.04
0.06
1.3
1.4
—
11.63
—
0
8
130
1268
1.02
0.05
1.2
1.3
—
—
—
0
0
53
510
1.03
0.05
1.5
1.7
—
9.08
—
0
22
506
5050
0.99
0.04
5.9
4.2
43.66
68.95
e6/l
1.05
369
3298
93
906
1.02
0.04
10.3
11.6
7.40
7.41
ph
0.38
38
442
25
237
1.05
0.04
1.2
1.1
—
—
—
0
0
540
5381
0.99
0.03
1.7
1.7
1.20
2.44
u/ml
3.61
158
1248
19
180
1.05
0.02
1.2
1.1
1.40
1.46
g/l
0.44
19
170
24
247
0.96
0.02
4.9
3.6
—
—
—
0
0
88
883
0.99
0.02
1.5
1.3
—
—
—
0
0
21
216
0.96
0.02
1.1
1.1
—
—
—
0
0
39
395
0.98
0.01
1.2
1.2
—
—
—
0
0
91
894
1.01
0.01
10.2
11.7
0.37
0.30
mmol/l
0.07
75
726
448
4438
1.00
0.00
9.0
6.9
—
—
—
0
0
16
153
1.04
0.00
2.8
2.4
18.50
108.50
ug/min
—
8
98
21
214
0.97
0.00
1.6
1.8
—
—
—
0
0
757
7505
1.00
0.00
3.3
2.9
—
14431.00
—
0
7
10
99
1.00
0.00
6.1
6.2
—
—
—
0
0
10
97
1.02
0.00
1.4
1.6
0.56
0.53
e9/l
—
10
97
33
322
1.02
0.00
1.5
1.7
0.72
0.77
g/l
0.11
26
265
26
258
1.00
0.00
1.1
1.3
3.54
4.54
u/ml
0.26
13
122
19
193
0.98
0.00
1.3
1.7
—
—
—
0
0
37
365
1.01
0.00
1.1
1.1
5.13
4.17
eliau/ml
0.09
17
127
24
240
0.99
0.00
3.0
7.4
1.38
1.21
mmol/l
0.60
19
213
84
831
1.00
0.00
1.8
2.2
—
—
—
0
0
61
609
0.99
0.00
1.4
1.2
—
—
—
0
0
28
275
1.01
0.00
2.1
1.9
1.71
1.27
ug/l
0.14
23
249
14
144
0.96
0.00
1.6
1.3
0.13
0.28
nmol/l
—
9
113
0
5
0.00
-0.00
0.0
1.6
—
400.40
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.0
—
6.97
—
0
7
6
62
0.96
-0.00
1.2
1.3
64.33
67.03
umol/l
—
6
62
0
7
0.00
-0.00
0.0
1.6
—
129.39
—
0
7
0
7
0.00
-0.00
0.0
1.4
—
2.17
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
1.5
1.6
130.00
152.97
mmol/24h
—
6
61
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
7532.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
386.63
—
0
8
7
77
0.90
-0.00
1.1
1.1
5.57
7.84
mm/h
—
7
77
7
78
0.89
-0.00
1.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.8
—
—
—
0
0
7
75
0.93
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.05
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
226.80
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
153.00
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
97
0.92
-0.00
1.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
80
0.99
-0.00
1.1
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_DISTAL_BITE and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
K11_DISTAL_BITE 0.943 [0.66, 1.34] 0.747
Birth year 0.987 [0.98, 1.0] 0.025

During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 28247 males with K11_DISTAL_BITE died.

Mortality risk

Mortality risk for people of age

years, who have K11_DISTAL_BITE.

N-year risk Females Males
1 No data 0.125%
5 No data 0.954%
10 No data 2.553%
15 No data 5.051%
20 No data 8.891%

Relationships between endpoints

Index endpoint: K11_DISTAL_BITE – Distal bite

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data