No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditions
|
556360 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
1788 |
4. Check minimum number of eventsNone |
1788 |
5. Include endpointsNone |
1788 |
6. Filter based on genotype QC (FinnGen only) |
1646 |
Control definitions (FinnGen only)
- Control conditions
- not K11_CLEFT_SYNDR
Extra metadata
- First used in FinnGen datafreeze
- DF10
Tooth agenesis EXCLUDE clefts and syndromes
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 37565 | 21955 | 15575 |
| Only index persons | 32984 | 19326 | 13658 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.55 | 0.63 | 0.44 |
| Only index persons | 0.63 | 0.71 | 0.52 |
| Median age at first event (years) | |||
| Whole population | 12.21 | 12.26 | 12.09 |
| Only index persons | 12.85 | 12.96 | 12.68 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1646 | 1209 | 437 |
| Unadjusted period prevalence (%) | 0.37 | 0.43 | 0.20 |
| Median age at first event (years) | 21.44 | 21.16 | 22.23 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1709
- Matched controls
- 17062
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
SBB10
NOMESCO Finland
Dental impressions
6.2
310.3
845
2320
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
223.4
307.7
198
10
K00.00
ICD-10 Finland
Hypodontia
+∞
307.7
1694
*
EBB10
NOMESCO Finland
Insertion of dental implant
147.2
307.7
431
39
SPC20
NOMESCO Finland
Implant borne crown
151.0
307.7
235
18
EBB15
NOMESCO Finland
Insertion of dental implant abutment
186.5
307.7
268
17
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
102.5
289.7
150
16
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
11.1
287.3
337
370
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
6.3
245.0
523
1120
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
6.7
226.2
427
807
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
18.7
226.2
185
110
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
5.5
203.3
496
1182
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
6.1
193.5
399
814
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
7.2
180.5
298
485
SAA04
NOMESCO Finland
Special examination of mouth
5.1
170.1
435
1066
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
17.8
161.8
134
81
K00.09
ICD-10 Finland
Lack of teeth due to lack of dental development UNS
38.8
160.3
99
27
SPC08
NOMESCO Finland
Implant crown
70.3
159.5
87
13
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
5.0
154.5
403
998
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
4.4
140.6
430
1201
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
4.6
137.0
385
1006
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
4.5
136.0
408
1121
EB1MA
NOMESCO Finland
Cephalometry with X-ray
4.6
133.3
372
965
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
5.5
123.8
267
556
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
4.7
119.2
314
774
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.1
109.6
1121
6447
SPF40
NOMESCO Finland
Removal and reattachment of crown or small bridge
26.6
106.8
74
29
SJC10
NOMESCO Finland
Orthodontic band in one tooth
4.2
105.1
324
897
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
4.0
104.7
351
1032
SAA03
NOMESCO Finland
Extended examination of mouth
3.1
99.2
1231
7696
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
3.3
98.9
472
1746
K07.13
ICD-10 Finland
Retrognaty, mandibular
6.7
98.8
165
267
SPA02
NOMESCO Finland
Preparation for dental prosthetics
10.0
96.4
113
120
K07.23
ICD-10 Finland
Deep bite
4.1
96.2
310
883
SXC05
NOMESCO Finland
Other oral or dental procedure
3.2
93.9
472
1795
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
9.0
92.2
117
138
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
4.4
87.8
247
634
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
15.9
86.5
75
49
SPC10
NOMESCO Finland
Standard dental crown
15.8
83.9
73
48
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
4.3
80.2
231
602
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
127.5
79.6
85
7
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
8.7
76.2
99
120
T84.60
ICD-10 Finland
Gingivitis associated with dental implants
31.4
74.8
49
16
WZC00
NOMESCO Finland
Treatment plan or consultation
2.5
74.5
960
5770
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
32.8
74.3
48
15
K07.14
ICD-10 Finland
Retrognaty, maxillary
11.8
71.8
74
65
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
21.8
71.0
53
25
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
3.2
67.9
307
1078
SXC03
NOMESCO Finland
Other oral or dental procedure
15.3
65.7
58
39
EEC05
NOMESCO Finland
Le Fort I osteotomy
21.9
65.7
49
23
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
3.1
62.6
303
1104
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
134.8
61.2
65
5
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
21.9
60.4
45
21
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
2.8
58.9
367
1533
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.7
57.9
381
1635
SPC30
NOMESCO Finland
Surface-retained bridge
24.6
57.6
41
17
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
24.6
57.6
41
17
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
7.5
55.7
81
112
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
3.6
55.0
203
624
EMAK, ,
NOMESCO Finland
4.7
54.6
134
306
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
12.4
53.1
53
44
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
3.0
51.5
256
941
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
13.2
51.2
49
38
SPA60
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 1 to 3 units
13.7
51.1
48
36
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.9
50.7
268
1019
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
8.5
46.8
61
74
WZA90
NOMESCO Finland
Other medical or dental certificate
2.1
46.0
636
3721
SPA05
NOMESCO Finland
Surgical guide
125.8
46.0
49
*
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
3.1
45.8
216
769
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.0
45.2
216
774
K07.24
ICD-10 Finland
Open bite
4.7
45.2
108
241
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
73.2
44.2
50
7
EB1WA, ,
NOMESCO Finland
13.0
43.5
42
33
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
15.5
43.4
38
25
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
2.0
41.8
1014
7184
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
6.8
41.7
66
100
SPC01
NOMESCO Finland
Fixed dental crown
8.4
41.1
54
66
EBA00
NOMESCO Finland
Extraction of tooth
2.0
39.9
899
6170
K07.33
ICD-10 Finland
Crowding of tooth or teeth
9.8
38.6
45
47
SPA30
NOMESCO Finland
Grinding of a single crown and bridge pillar or a single post and crown
8.8
37.9
48
56
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
3.0
37.5
176
622
SPF41
NOMESCO Finland
Repair of dental crown, bridge or implant structure, standard
9.4
37.5
45
49
SPB06
NOMESCO Finland
Production of temporary clinic-made tooth- or implant-retained crown or bridge unit
13.8
36.5
34
25
OIKK, ,
NOMESCO Finland
2.4
35.2
285
1323
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.6
34.4
120
353
POLI, ,
NOMESCO Finland
122.3
33.8
36
*
SPC09
NOMESCO Finland
Implant crown, demanding
118.9
32.8
35
*
SAALT, ,
NOMESCO Finland
3.5
31.0
112
337
SPA40
NOMESCO Finland
Precision impression for dental prosthesis
43.0
30.9
38
9
ECB20
NOMESCO Finland
Oral alveoplasty
11.6
30.9
32
28
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
4.5
29.6
74
171
SAA02
NOMESCO Finland
Basic examination of mouth
2.4
28.0
1518
13162
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
7.3
28.0
41
57
K00.01
ICD-10 Finland
Anodontia
285.6
27.8
28
*
K01.0
ICD-10 Finland
Embedded teeth
3.2
27.5
114
374
SAA01
NOMESCO Finland
Simple examination of mouth
2.1
27.3
1452
12403
EB1S1
NOMESCO Finland
Photography of teeth
5.5
26.7
52
97
T84.62
ICD-10 Finland
Osteitis associated with dental implants
46.4
26.5
32
7
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.9
24.8
120
430
K07.60
ICD-10 Finland
Snapping jaw
2.5
24.3
163
690
SPB20
NOMESCO Finland
Temporary bridge
25.8
24.0
33
13
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
9.2
23.8
29
32
K07.10
ICD-10 Finland
Asymmetry of jaw
8.3
23.5
31
38
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
7.9
23.4
32
41
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
6.3
22.7
38
61
SPC35
NOMESCO Finland
Production and attachment of fibre-reinforced dental bridge
9.4
22.6
27
29
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
5.1
22.1
47
95
OIKH, ,
NOMESCO Finland
2.2
21.9
194
927
ECA55
NOMESCO Finland
Complicated periodontal flap surgery
21.7
20.8
30
14
EEC45
NOMESCO Finland
Reconstruction of maxilla using bone graft
74.3
19.7
22
*
SPE90
NOMESCO Finland
Other partial denture
8.4
19.2
25
30
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
2.1
19.2
196
989
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
19.1
1357
11728
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
26.3
19.1
26
10
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
2.7
18.7
103
396
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
3.7
18.4
59
164
SPF20
NOMESCO Finland
Temporary relining of dentures
44.4
18.2
22
5
ECA70
NOMESCO Finland
Regenerative periodontal surgery or gingival graft
17.7
18.2
28
16
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
2.0
18.2
219
1173
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
6.3
18.0
30
48
SPC25
NOMESCO Finland
Other demanding attachment of prosthodontic crown
53.0
18.0
21
*
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
14.7
17.6
29
20
ECB10
NOMESCO Finland
Reconstruction of gingiva
29.1
17.4
23
8
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
2.7
17.1
92
349
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
19.5
16.9
25
13
SPB30
NOMESCO Finland
Temporary partial denture
63.9
16.7
19
*
ECA00
NOMESCO Finland
Surgical exposure of tooth
4.2
16.7
44
106
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.9
16.7
244
1393
K00.0
ICD-10 Finland
Anodontia
+∞
16.7
16
*
SPF50
NOMESCO Finland
Removal and reattachment of bridge
35.3
16.7
21
6
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
35.3
16.7
21
6
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.0
16.6
210
1143
EAB10
NOMESCO Finland
Excision and repair of frenum of lip
7.3
16.5
24
33
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.5
15.7
704
5358
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
161.2
15.5
16
*
K01.12
ICD-10 Finland
Retained canine with obstruction in the upper jaw
4.8
15.2
34
72
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
15.1
820
6480
SDA03
NOMESCO Finland
Periodontal treatment
1.5
15.0
706
5412
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
15.0
139
674
OIKKK, ,
NOMESCO Finland
5.0
15.0
32
65
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
3.0
14.9
66
225
EB1TW
NOMESCO Finland
3D modelling of dentition
12.0
14.6
26
22
SAE01, ,
NOMESCO Finland
4.0
14.4
41
105
ECU00
NOMESCO Finland
Removal of implant or external fixation device from alveoli
42.8
14.1
17
*
ZXX04
NOMESCO Finland
Extent of procedure, 4 units
12.0
14.1
25
21
SPC06
NOMESCO Finland
Fixed dental bridge pontic or bridge or crown lug
23.9
13.8
19
8
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.6
13.7
78
305
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.7
13.6
266
1650
Z01.2
ICD-10 Finland
Dental examination
1.5
13.6
1024
8571
SPA01
NOMESCO Finland
Pre-prosthetic dental procedures
25.9
13.4
18
7
K03.64
ICD-10 Finland
Dental calculus supragingival
1.5
12.7
775
6194
EBB20
NOMESCO Finland
Transplantation of tooth
+∞
12.5
12
*
K00.21
ICD-10 Finland
Macrodontia
130.7
12.4
13
*
OIKAL, ,
NOMESCO Finland
2.3
12.3
98
448
SFB30
NOMESCO Finland
Indirect three-surface restoration
14.4
12.3
20
14
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
9.7
12.2
24
25
SBA00
NOMESCO Finland
Microbiological examinations
3.1
12.1
50
164
K07.00
ICD-10 Finland
Macrognatia (hyperplasia) of the upper jaw
26.8
12.0
16
6
OIKRE, ,
NOMESCO Finland
3.2
12.0
48
155
ECW06
NOMESCO Finland
Insertion of mini-implant or miniscrew
30.2
11.6
15
5
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
2.3
11.6
84
368
SPB15
NOMESCO Finland
Temporary dental implant crown
65.3
11.6
13
*
SPF42
NOMESCO Finland
Repair of dental crown, bridge or implant structure, demanding
35.2
11.3
14
*
ZXX03
NOMESCO Finland
Extent of procedure, 3 units
8.9
11.2
23
26
WYA10
NOMESCO Finland
Emergency care or similar visit
1.8
10.8
159
906
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
10.8
507
3828
SPB07
NOMESCO Finland
Temporary denture
21.6
10.7
15
7
SPF10
NOMESCO Finland
Demanding reparation of dental prosthesis
10.1
10.5
20
20
52000
ICD-8 Finland
Disorder of tooth development and eruption, Anodontia
+∞
10.4
10
*
SCD01
NOMESCO Finland
Removal of biofilm and supragingival calculus, short
3.1
10.4
43
142
SPA45
NOMESCO Finland
Precision impression for dental prosthesis, demanding
32.7
10.3
13
*
SPA61
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 4 to 6 units
10.6
10.3
19
18
SPC31
NOMESCO Finland
Surface-retained dental bridge, reproduced outside mouth
18.9
10.3
15
8
-1, ,
NOMESCO Finland
1.4
10.2
818
6775
YNA09
NOMESCO Finland
Other excision of bone for transplantation
16.8
9.9
15
9
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
2.8
9.8
49
180
OIKVA, ,
NOMESCO Finland
2.0
9.7
109
568
ZXA10
NOMESCO Finland
Bilateral
1.6
9.5
226
1469
ECB60
NOMESCO Finland
Reconstruction of alveolus
+∞
9.4
9
*
ZZH22
NOMESCO Finland
Graft of patients own bone, block
12.4
9.3
16
13
SPA47
NOMESCO Finland
Precision impression for denture
4.0
9.3
26
66
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.4
9.3
486
3726
K01.14
ICD-10 Finland
Retained premolar with obstruction in the upper jaw
10.1
9.0
17
17
EBW99
NOMESCO Finland
Other operation on tooth
24.1
8.9
12
5
SFA10
NOMESCO Finland
One-surface restoration
1.4
8.9
1046
9131
K03.30
ICD-10 Finland
Internal granuloma of pulp
8.6
8.8
18
21
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
1.7
8.7
155
934
ECW05
NOMESCO Finland
Restricted insertion of mini-implant or miniscrew
50.2
8.7
10
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
8.7
294
2070
YEA05
NOMESCO Finland
Excision of gingival or connective tissue for transplantation
20.1
8.5
12
6
EFB60
NOMESCO Finland
Osteoplasty of jaws or facial bones with use of osseous graft or foreign material
90.3
8.4
9
*
SPC11
NOMESCO Finland
Fixed implant bridge pontic or implant bridge or crown lug
+∞
8.3
8
*
SDA12
NOMESCO Finland
Treatment of complicated periodontal disease
3.8
8.3
25
67
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
8.6
8.3
17
20
XX1VW
NOMESCO Finland
Written report from radiologist
4.8
8.1
18
38
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
3.8
8.1
24
64
Z01.9
ICD-10 Finland
Special examination, unspecified
2.0
8.0
85
436
SJE90
NOMESCO Finland
Orthodontic finishing
3.1
8.0
32
104
SAE03, ,
NOMESCO Finland
4.6
7.9
18
39
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.4
7.8
27
80
R01AD58
ATC
fluticasone, combinations; nasal
1.4
7.8
470
3674
K03.5
ICD-10 Finland
Ankylosis of teeth
15.1
7.7
12
8
SPB05
NOMESCO Finland
Temporary prefabricated or laboratory-made dental or implant crown or bridge unit
18.4
7.6
11
6
XX7LW, ,
NOMESCO Finland
18.4
7.6
11
6
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
10.1
7.5
14
14
K06.00
ICD-10 Finland
Local gingivore traction
2.5
7.5
45
182
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
7.5
349
2609
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.4
7.5
362
2724
SPC45
NOMESCO Finland
Preparation of third or later intermediate attachment tooth for bridge
+∞
7.3
7
*
K05.30
ICD-10 Finland
Periodontitis complex
1.7
7.2
138
849
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.1
7.2
63
301
K05.22
ICD-10 Finland
Acute pericoronitis
0.5
7.1
80
1440
SPC05
NOMESCO Finland
Fixed dental crown, demanding
12.1
7.1
12
10
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
7.1
522
4200
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.3
7.1
689
5773
K07.34
ICD-10 Finland
Rotation of tooth or teeth
10.0
7.0
13
13
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.4
7.0
24
71
HMAK, ,
NOMESCO Finland
1.6
6.9
158
1018
WX725
NOMESCO Finland
Noninvasive ventilation
2.0
6.9
69
347
OIKJA, ,
NOMESCO Finland
2.6
6.9
37
142
EB1VA, ,
NOMESCO Finland
1.5
6.9
256
1833
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
3.5
6.8
23
67
SPF30
NOMESCO Finland
Relining of denture
6.7
6.8
16
24
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
9.3
6.8
13
14
K00.9
ICD-10 Finland
Disorder of tooth development, unspecified
40.1
6.8
8
*
137
Kela drug reimbursment
Uraemia requiring dialysis
4.3
6.7
17
40
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.6
6.7
153
984
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.0
6.7
69
351
EBA10
NOMESCO Finland
Operative extraction of tooth
1.4
6.6
383
2962
K05.31
ICD-10 Finland
Periodontitis pronounced
1.9
6.6
85
466
K00.29
ICD-10 Finland
Other or indefinite deviation in the shape or size of the teeth
12.3
6.6
11
9
Z94.0
ICD-10 Finland
Kidney transplant status
3.4
6.5
23
69
K03.66
ICD-10 Finland
Tooth plaque
1.5
6.5
192
1309
T84.64
ICD-10 Finland
Other infection or inflammatory reaction associated with dental implants
70.0
6.4
7
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.9
6.4
73
385
K03.00
ICD-10 Finland
Approximal wear
1.6
6.3
136
862
J01FF01
ATC
clindamycin; systemic
1.4
6.3
288
2140
K01.15
ICD-10 Finland
Retained premolar with obstruction in the lower jaw
11.0
6.3
11
10
D19
ICPC
Teeth/gum symptom/complaint
1.3
6.3
607
5057
EB1S1, ,
SPAT
18.1
6.3
9
5
SXC04
NOMESCO Finland
Other oral or dental procedure, extensive
18.1
6.3
9
5
XKC03
NOMESCO Finland
Water cystometry
2.8
6.3
29
103
4313
FHL
Internal / external fixation of the implant
+∞
6.2
6
*
T84.61
ICD-10 Finland
Gingival growth associated with dental implants
+∞
6.2
6
*
TEB00
NOMESCO Finland
Restoration of crown of tooth
+∞
6.2
6
*
5200A
ICD-9 Finland
Disorders of tooth development and eruption, Anodontia
+∞
6.2
6
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.2
6.2
52
244
EBB10, ,
SPAT
26.7
6.2
8
*
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.5
6.2
192
1323
602
Kela drug reimbursment
Children's severe malnutrition
2.6
6.2
34
132
KMAK, ,
NOMESCO Finland
1.3
6.2
665
5616
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.9
6.2
69
361
K07.4
ICD-10 Finland
Malocclusion, unspecified
2.3
6.2
46
206
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
6.2
137
876
A11CC03
ATC
alfacalcidol; systemic
2.7
6.2
31
115
EBA40
NOMESCO Finland
Extraction of apex of root of tooth
5.0
6.2
18
36
EB1HA, ,
SPAT
2.1
6.1
52
246
WX002
NOMESCO Finland
Sedation and analgesia
1.5
6.0
179
1224
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
818
7262
1.24
4.56
6.1
5.1
6.12
6.17
mmol/l
0.28
741
6634
712
6247
1.24
4.37
3.2
2.9
—
—
estimate
—
0
0
268
2089
1.33
4.29
3.7
2.5
15.08
14.58
umol/l
0.40
254
1965
16
51
3.15
4.20
3.9
5.7
—
—
—
0
0
224
1708
1.36
4.15
3.9
2.6
23.93
23.27
%
0.30
211
1601
61
354
1.75
4.05
10.0
7.7
159.80
348.76
iu/ml
—
10
38
245
1918
1.32
3.80
3.8
2.5
2.53
2.53
g/l
0.05
227
1784
106
723
1.49
3.68
4.3
3.9
1.23
1.23
mmol/l
0.20
93
617
514
4428
1.23
3.60
3.7
2.7
0.36
0.05
estimate
0.55
177
1305
94
633
1.51
3.48
5.3
4.5
3.20
3.26
g/l
0.16
87
611
12
31
3.88
3.48
7.5
8.6
—
—
—
0
0
73
465
1.59
3.46
1.9
1.8
112.64
121.04
au/ml
0.21
22
149
1016
9370
1.20
3.44
8.1
6.7
81.37
80.84
u/l
0.13
965
8904
209
1623
1.33
3.44
2.5
2.2
348.68
380.41
nmol/l
1.81
198
1537
1411
13490
1.25
3.13
5.4
5.0
1.79
1.79
mu/l
0.02
1358
12901
215
1699
1.30
3.13
4.5
3.2
29.37
29.58
s
0.22
209
1659
1072
9982
1.19
3.10
4.7
4.1
8.21
8.12
mm/h
0.09
1025
9407
10
25
4.01
3.08
1.4
3.3
0.62
0.63
mmol/l
—
10
25
12
36
3.34
3.01
5.7
7.1
71747.50
987730.00
u/ml
—
6
10
12
36
3.34
3.01
5.4
7.0
—
—
—
0
0
79
535
1.50
2.90
1.6
1.7
—
—
—
0
0
181
1426
1.30
2.71
1.9
1.6
16.35
15.57
iu/l
0.16
147
1134
1262
11984
1.20
2.70
4.6
4.3
14.28
14.33
pmol/l
0.35
1150
11048
57
367
1.57
2.65
1.9
2.5
1.09
1.25
g/l
0.89
51
334
71
481
1.49
2.63
4.4
3.1
140.44
128.32
ng/l
0.06
63
424
156
1216
1.31
2.54
1.8
1.8
—
—
—
0
0
450
3941
1.19
2.54
3.9
3.3
0.00
0.00
estimate
1.08
197
1519
650
5871
1.17
2.53
6.6
5.8
10.46
10.69
umol/l
0.18
615
5512
15
62
2.43
2.53
2.9
3.5
26.20
55.40
u/ml
0.63
15
62
533
4739
1.18
2.52
6.8
5.4
37.58
37.79
g/l
0.44
510
4477
85
605
1.42
2.46
5.2
5.7
132.44
131.38
g/l
0.20
80
584
636
5747
1.17
2.44
10.5
7.5
1.22
1.22
mmol/l
0.11
558
5112
6
12
5.01
2.40
1.5
3.8
—
—
—
0
0
9
28
3.22
2.30
2.3
2.5
—
—
—
0
0
146
1148
1.29
2.26
2.2
2.2
10.23
10.51
nmol/l
0.13
134
1058
282
2399
1.21
2.18
1.3
1.3
11.94
9.33
u/ml
0.24
106
924
58
395
1.48
2.14
1.3
1.3
—
—
—
0
0
27
152
1.79
2.11
1.6
1.4
—
—
—
0
0
27
152
1.79
2.11
1.6
1.4
—
—
—
0
0
305
2622
1.20
2.11
1.3
1.3
24.98
23.38
iu/ml
0.09
81
672
26
145
1.80
2.10
1.7
1.4
—
—
—
0
0
26
146
1.79
2.06
1.7
1.4
—
—
—
0
0
27
154
1.76
2.03
1.6
1.4
—
—
—
0
0
26
147
1.78
2.02
1.7
1.4
—
—
—
0
0
34
208
1.64
2.00
6.3
4.5
6.31
6.89
pmol/l
0.17
34
208
86
639
1.36
1.99
1.8
1.6
250.70
193.98
u/ml
0.84
44
329
137
1089
1.28
1.97
2.1
1.7
6.34
7.91
u/l
1.78
105
823
622
5682
1.15
1.97
3.8
3.0
0.05
0.02
estimate
0.76
177
1314
414
3673
1.17
1.96
3.2
2.6
54.33
58.63
u/l
1.53
385
3426
1519
14792
1.23
1.93
14.1
11.7
68.36
67.20
umol/l
0.85
1497
14610
80
591
1.37
1.93
1.6
1.6
—
—
—
0
0
40
258
1.56
1.92
1.3
1.3
—
—
—
0
0
1398
13513
1.18
1.91
4.0
3.9
—
—
—
0
0
53
364
1.47
1.91
1.6
1.4
17.62
15.74
u/l
0.20
48
316
31
188
1.66
1.90
1.2
1.6
0.57
0.50
e9/l
0.76
31
188
824
7686
1.14
1.88
4.0
3.3
0.02
3.06
estimate
1.05
203
1572
147
1187
1.26
1.87
1.8
1.8
—
—
—
0
0
203
1699
1.22
1.86
2.0
1.9
—
—
—
0
0
427
3823
1.15
1.78
2.7
2.6
2.38
2.54
mg/l
1.20
383
3352
109
855
1.29
1.77
1.4
1.5
—
—
—
0
0
98
1250
0.77
1.76
1.6
1.6
62.71
60.07
ug/l
0.23
86
1067
1397
13527
1.17
1.75
14.0
11.1
3.90
3.89
mmol/l
0.23
1357
13152
824
7710
1.13
1.75
4.1
3.4
0.01
0.00
estimate
0.24
198
1530
148
1207
1.25
1.75
3.6
3.6
0.22
0.22
g/l
0.00
138
1146
591
5417
1.14
1.75
1.6
1.6
1.96
1.92
u/ml
0.03
153
1387
15
74
2.03
1.74
1.1
1.3
—
—
—
0
0
17
88
1.94
1.74
1.3
1.1
99.75
91.73
%
—
8
44
12
54
2.23
1.73
1.7
1.8
197.83
180.70
u/l
0.30
12
54
29
178
1.64
1.72
3.6
3.7
228.55
177.76
e6/l
0.79
22
140
35
226
1.56
1.70
2.3
1.9
—
—
—
0
0
17
89
1.92
1.69
1.4
1.3
—
—
—
0
0
215
1832
1.20
1.66
8.8
5.8
0.81
0.82
mmol/l
1.02
207
1763
812
7612
1.12
1.64
4.1
3.3
0.00
0.00
estimate
0.41
204
1583
1395
13526
1.16
1.63
13.9
11.1
139.49
139.56
mmol/l
0.63
1354
13205
5
14
3.57
1.61
1.0
1.4
—
—
—
0
0
135
1101
1.24
1.61
5.8
4.8
236.16
234.49
u/l
0.05
128
1064
277
2422
1.17
1.58
3.6
2.8
302.93
312.85
umol/l
1.02
259
2227
85
656
1.31
1.58
1.4
1.4
4.28
3.98
ug/l
0.08
79
620
1376
13337
1.15
1.57
16.6
14.0
13.15
13.16
%
0.13
1359
13153
171
1435
1.21
1.56
1.4
1.4
136.97
335.36
u/ml
2.54
161
1337
39
264
1.49
1.55
4.4
3.0
20.61
25.83
mg/l
0.62
24
179
26
160
1.63
1.55
2.6
3.7
—
—
—
0
0
46
324
1.43
1.51
3.4
3.4
24.65
23.30
mu/l
0.08
46
303
108
868
1.26
1.48
15.2
10.5
0.81
0.37
mmol/l
0.65
84
711
1491
14556
1.18
1.47
13.4
11.1
19.99
20.37
mg/l
0.17
1174
11231
1159
11129
1.12
1.47
4.2
4.1
35.93
36.46
mmol/mol
1.70
1110
10642
113
916
1.25
1.44
2.4
2.6
—
—
—
0
0
12
59
2.04
1.43
1.4
1.2
18.16
16.32
umol/l
0.55
12
52
972
9255
1.11
1.40
5.1
4.0
385.35
973.05
e6/l
0.51
23
92
210
1819
1.17
1.37
3.5
3.0
291.62
664.70
ng/l
1.35
105
929
9
41
2.20
1.36
1.6
1.4
—
—
—
0
0
9
42
2.15
1.33
2.8
2.1
—
—
—
0
0
9
42
2.15
1.33
1.6
1.4
—
—
—
0
0
9
42
2.15
1.33
2.8
2.1
—
—
—
0
0
900
8550
1.11
1.33
10.6
9.4
3.78
3.84
e9/l
0.37
801
7386
421
3840
1.13
1.31
3.3
2.8
2.36
2.36
mmol/l
0.45
384
3568
1508
14764
1.17
1.28
10.5
9.3
25.76
25.37
u/l
0.27
1471
14379
107
876
1.23
1.28
15.4
10.5
4.94
5.06
kpa
0.88
102
842
938
8943
1.10
1.27
4.4
3.4
64.12
66.42
ug/l
0.17
897
8550
8
36
2.22
1.24
1.6
1.3
13.25
12.33
u/l
—
8
36
110
907
1.23
1.24
1.2
1.2
1.76
3.34
u/ml
1.21
66
537
76
601
1.27
1.23
1.1
1.1
7.11
6.71
eliau/ml
—
8
92
99
810
1.23
1.20
1.9
1.7
—
—
—
0
0
98
802
1.23
1.19
1.1
1.1
0.59
1.54
u/ml
1.85
48
427
199
1742
1.16
1.16
3.9
3.7
816.97
705.44
ng/l
0.14
152
1356
50
377
1.33
1.15
2.1
1.8
—
—
—
0
0
100
825
1.22
1.14
1.1
1.1
9.08
7.64
u/ml
0.28
60
520
26
175
1.49
1.12
3.4
3.7
504.42
498.38
e6/l
0.02
19
133
15
88
1.71
1.11
1.4
1.2
92.50
90.07
%
—
6
44
323
2932
1.12
1.10
2.7
3.0
83.67
103.37
ug/g
0.83
260
2322
1031
9918
1.10
1.08
3.5
3.3
33.11
32.20
u/l
0.25
993
9550
7
32
2.19
1.08
1.6
1.5
—
—
—
0
0
38
278
1.37
1.07
1.3
1.4
—
—
—
0
0
27
186
1.46
1.05
1.7
1.7
—
—
—
0
0
75
606
1.25
1.05
1.1
1.1
7.11
8.51
u/ml
0.24
37
322
673
6360
1.09
1.04
3.4
2.8
72.37
69.79
nmol/l
1.70
630
6026
9
46
1.96
1.03
2.8
2.0
—
—
—
0
0
97
1153
0.83
1.01
1.5
1.5
1.21
1.14
ratio
0.33
62
685
23
155
1.49
1.00
1.4
1.5
—
—
—
0
0
0
30
0.00
0.97
0.0
1.2
—
—
—
0
0
325
2974
1.11
0.97
2.7
2.2
1.01
1.01
mg/l
0.01
238
2137
7
36
1.95
0.97
1.4
1.7
—
—
—
0
0
96
1136
0.83
0.96
1.5
1.5
—
—
—
0
0
20
132
1.52
0.96
2.3
1.8
—
—
—
0
0
98
1156
0.84
0.95
1.5
1.5
1.18
1.19
ratio
0.06
63
693
98
1156
0.84
0.95
1.5
1.5
0.94
0.94
ratio
0.01
63
688
203
1809
1.14
0.95
13.6
7.9
1.18
1.16
mmol/l
0.47
193
1719
11
62
1.78
0.93
2.5
1.8
—
—
—
0
0
11
62
1.78
0.93
2.5
1.8
—
—
—
0
0
11
62
1.78
0.93
2.5
1.8
—
—
—
0
0
11
62
1.78
0.93
2.5
1.8
—
—
—
0
0
34
251
1.36
0.93
2.1
1.7
0.80
1.49
ug/l
0.99
28
229
32
234
1.37
0.93
1.4
1.4
—
—
—
0
0
171
1509
1.15
0.92
5.2
3.8
8.25
6.03
umol/l
0.58
154
1275
1166
11322
1.09
0.90
3.3
3.2
1.19
1.17
mmol/l
0.40
1113
10771
95
802
1.19
0.90
1.1
1.1
2.27
3.01
u/ml
0.28
55
483
85
1008
0.83
0.89
3.5
4.2
—
—
—
0
0
9
155
0.58
0.88
1.0
1.1
—
—
—
0
0
503
4724
1.09
0.88
1.6
1.5
1.96
1.93
g/l
0.18
323
2901
12
193
0.62
0.88
1.1
1.0
—
—
—
0
0
68
557
1.23
0.87
1.0
1.1
0.72
0.32
u/ml
0.27
24
192
1644
16273
1.23
0.87
20.1
17.0
262.17
264.56
e9/l
0.90
1622
15915
28
203
1.38
0.86
1.3
1.3
—
—
—
0
0
46
361
1.28
0.85
2.1
1.7
—
—
—
0
0
355
3288
1.10
0.84
1.6
1.6
—
—
—
0
0
32
239
1.34
0.83
1.1
1.1
3.10
6.01
iu/ml
—
7
56
1644
16279
1.22
0.82
20.0
16.9
88.96
88.86
fl
0.42
1636
16129
38
293
1.30
0.81
2.2
2.6
134.42
133.93
g/l
0.06
31
254
540
5106
1.08
0.80
11.1
7.5
1.22
1.22
mmol/l
0.54
514
4800
123
1074
1.15
0.79
3.5
3.5
4.82
4.75
pmol/l
0.25
109
981
230
2091
1.11
0.79
2.4
2.4
6999.68
7213.82
u/l
0.03
81
746
1645
16293
1.21
0.79
20.1
17.0
6.60
6.71
e9/l
1.70
1621
15890
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
27
361
0.74
0.79
1.3
2.0
—
—
—
0
0
6
33
1.82
0.79
1.5
1.4
—
—
—
0
0
6
33
1.82
0.79
1.5
1.4
—
—
—
0
0
1644
16283
1.21
0.78
21.0
17.3
40.24
40.91
%
1.19
1635
16124
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
29
216
1.35
0.78
11.4
7.0
0.26
0.34
iu/ml
0.89
16
108
1644
16284
1.21
0.77
20.1
16.9
4.55
4.58
e12/l
1.39
1620
15895
14
90
1.56
0.77
1.2
1.3
117.00
66.24
ug/l
0.57
14
90
30
225
1.34
0.77
2.5
2.3
—
—
—
0
0
42
331
1.27
0.77
1.7
1.4
362.43
320.99
ug/g
0.65
27
158
89
761
1.18
0.76
1.8
1.7
—
—
—
0
0
27
200
1.35
0.76
1.8
1.7
—
—
—
0
0
99
855
1.17
0.75
9.7
5.7
80.29
64.86
ng/l
0.83
93
803
13
83
1.57
0.74
2.9
3.9
759.46
663.48
u/ml
0.20
13
83
110
962
1.15
0.71
1.5
1.6
51.60
60.20
ug/l
1.95
110
962
1644
16292
1.20
0.71
20.2
17.1
135.07
135.47
g/l
0.64
1636
16141
296
2745
1.09
0.70
4.1
2.8
6.90
8.77
e6/l
1.50
273
2466
1241
12133
1.08
0.70
10.4
9.0
99.86
100.09
ml/min/173m2
0.13
1075
10338
23
169
1.36
0.69
2.1
1.7
—
—
—
0
0
46
373
1.24
0.68
1.1
1.1
3.83
3.30
eliau/ml
0.10
16
151
5
27
1.85
0.68
1.0
1.1
—
—
—
0
0
20
144
1.39
0.67
1.3
1.3
—
—
—
0
0
126
1119
1.13
0.67
1.6
1.7
—
—
—
0
0
7
43
1.63
0.66
5.3
3.1
1.52
1.90
ratio
—
7
36
7
43
1.63
0.66
1.0
1.1
—
—
—
0
0
5
94
0.53
0.66
3.0
1.1
—
—
—
0
0
5
28
1.79
0.66
3.8
4.8
6.74
4.97
kpa
—
5
28
5
28
1.79
0.66
1.0
1.2
—
—
—
0
0
1257
12307
1.07
0.65
4.0
3.9
2.68
2.75
mmol/l
2.34
1206
11747
380
3573
1.08
0.65
3.3
3.0
1.02
2.40
kg/l
1.08
245
2210
12
78
1.54
0.65
1.6
1.4
—
—
—
0
0
31
393
0.78
0.65
1.3
1.2
—
—
—
0
0
21
154
1.37
0.64
1.2
1.4
—
—
—
0
0
64
542
1.19
0.63
4.1
4.2
6.36
16.04
ug/l
0.50
47
394
32
251
1.28
0.63
1.1
1.2
112.09
113.98
%
0.16
32
226
181
1650
1.11
0.62
1.3
1.3
123.63
151.35
u/ml
0.42
70
608
311
2907
1.08
0.62
2.4
2.2
179.97
195.05
u/l
0.14
304
2784
117
1042
1.13
0.61
1.8
1.8
—
—
—
0
0
193
1769
1.10
0.60
2.4
2.1
2.40
2.41
mmol/l
0.47
167
1557
63
536
1.18
0.60
1.5
1.6
0.37
0.36
nmol/l
0.02
50
445
648
6228
1.06
0.59
1.9
1.9
—
—
—
0
0
11
162
0.68
0.59
9.0
13.0
0.61
0.59
mmol/l
0.14
11
154
140
1264
1.12
0.58
1.6
1.6
1094.34
1101.53
nmol/l
0.04
114
985
140
1264
1.12
0.58
11.4
8.6
104.97
105.11
mmol/l
0.14
140
1264
80
913
0.87
0.58
1.7
1.6
0.37
0.23
mg/l
0.71
28
392
1219
11945
1.07
0.57
3.6
3.4
5.45
5.52
mmol/l
1.51
1153
11237
75
651
1.16
0.57
1.1
1.1
11.76
5.70
u/ml
0.40
45
371
438
4163
1.07
0.56
4.5
3.4
31.67
51.29
e6/l
0.71
327
3066
6
36
1.67
0.56
3.2
3.9
45.00
75.81
u/l
—
6
36
46
547
0.84
0.56
1.7
1.5
—
—
—
0
0
13
90
1.45
0.55
1.5
1.7
—
—
—
0
0
134
1214
1.11
0.54
4.6
3.7
1.34
1.81
ug/l
0.81
124
1099
114
1026
1.12
0.52
2.4
2.3
14.97
17.73
au/ml
0.17
12
119
162
1486
1.10
0.52
9.5
7.2
1.65
1.40
mmol/l
0.60
137
1262
14
191
0.73
0.51
1.1
1.0
—
—
—
0
0
142
1296
1.10
0.50
3.4
3.2
10.03
10.34
g/l
0.59
133
1217
339
3208
1.07
0.50
3.6
2.4
—
—
—
0
0
19
144
1.32
0.50
1.7
1.2
—
—
—
0
0
1243
12209
1.06
0.50
3.7
3.6
1.46
1.46
mmol/l
0.11
1193
11646
37
306
1.21
0.50
1.4
1.4
—
—
—
0
0
47
398
1.18
0.50
2.3
2.1
—
—
—
0
0
19
246
0.77
0.50
4.5
6.2
390.00
391.45
umol/l
0.02
19
219
27
216
1.25
0.49
1.1
1.2
—
17.82
—
0
10
19
145
1.31
0.48
1.7
1.2
—
—
—
0
0
64
729
0.87
0.48
1.4
1.7
4.64
3.55
mg/l
0.52
44
500
7
46
1.52
0.48
1.1
1.2
38.14
33.13
u/l
—
7
38
21
163
1.29
0.48
1.9
1.4
1.69
5.31
u/ml
1.78
12
94
23
181
1.27
0.47
1.4
2.6
—
—
—
0
0
487
4673
1.06
0.47
1.8
1.7
101.34
97.46
pmol/l
1.22
288
2620
7
49
1.43
0.46
1.1
1.2
285.57
82.27
u/l
—
7
40
13
95
1.37
0.43
2.3
1.7
—
—
—
0
0
13
95
1.37
0.43
2.3
1.7
—
—
—
0
0
13
95
1.37
0.43
2.3
1.7
—
—
—
0
0
77
687
1.12
0.43
1.5
2.1
3.08
6.90
iu/ml
1.94
12
147
5
31
1.61
0.43
1.6
1.4
11.92
8.88
ug/l
—
5
31
103
935
1.11
0.43
3.3
3.4
20.95
22.16
%
0.26
32
315
12
87
1.38
0.42
1.2
1.1
15.44
37.79
iu/ml
2.25
12
87
1249
12296
1.05
0.41
3.9
3.6
4.56
4.60
mmol/l
0.84
1203
11785
5
33
1.51
0.41
1.8
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.0
1.7
9.92
4.59
nmol/l
—
5
27
0
18
0.00
0.40
0.0
2.2
—
2.63
—
0
9
309
2943
1.06
0.39
1.7
1.5
20.06
19.35
nmol/l
0.45
279
2627
86
778
1.11
0.39
1.4
1.3
—
—
—
0
0
14
106
1.32
0.38
8.9
4.8
0.86
0.73
index
0.30
14
106
16
124
1.29
0.38
1.1
1.0
1361.63
1454.37
miu/ml
0.18
16
124
20
160
1.25
0.38
1.6
1.7
—
—
—
0
0
120
1106
1.09
0.38
7.2
6.0
1.20
1.15
mmol/l
0.08
79
788
9
67
1.34
0.38
1.1
1.1
—
—
—
0
0
33
280
1.18
0.37
1.3
1.2
—
—
—
0
0
9
69
1.30
0.37
1.6
1.6
—
—
—
0
0
92
840
1.10
0.36
7.9
6.6
10.00
9.72
kpa
0.76
86
815
13
168
0.77
0.36
2.0
2.5
22.65
87.00
ug/min
—
6
114
6
41
1.46
0.36
3.2
2.6
26.37
32.78
umol/l
—
6
30
351
3366
1.05
0.36
2.9
2.6
16.48
62.64
ng/l
0.96
148
1431
59
526
1.12
0.35
3.9
2.4
1.02
1.02
ratio
0.56
54
465
37
426
0.86
0.35
1.2
1.1
—
—
—
0
0
9
125
0.72
0.35
1.7
1.6
—
—
—
0
0
6
43
1.39
0.35
1.8
2.2
—
16.69
—
0
13
17
135
1.26
0.35
1.5
1.4
1146.65
420.27
mu/l
0.67
17
130
121
1122
1.08
0.34
1.3
1.3
236.73
228.77
miu/ml
0.09
59
560
22
181
1.22
0.34
1.5
1.5
—
—
—
0
0
14
177
0.79
0.33
1.3
1.6
0.00
0.00
g/l
-0.00
14
171
45
396
1.14
0.33
1.6
1.6
385.56
354.29
mu/l
0.24
36
332
16
127
1.26
0.33
1.1
1.2
100.13
118.48
pmol/l
1.12
16
127
19
231
0.82
0.33
1.2
1.7
3.31
3.62
g/l
0.61
19
226
19
231
0.82
0.33
1.2
1.7
4.13
4.31
g/l
0.55
19
225
6
87
0.69
0.33
2.8
2.3
14.82
16.75
umol/l
—
6
87
127
1184
1.08
0.32
7.4
5.9
4.99
5.12
kpa
1.72
121
1145
81
741
1.10
0.32
2.8
2.5
78.38
82.48
ml/min/173m2
0.36
26
283
228
2170
1.06
0.31
3.4
3.1
4.78
4.09
e6/l
0.24
107
990
17
137
1.24
0.31
1.5
1.3
72.71
74.80
%
0.25
17
132
381
3675
1.05
0.31
4.0
3.3
0.18
0.29
e6/l
1.82
276
2607
37
421
0.87
0.31
1.2
1.1
—
—
—
0
0
81
880
0.91
0.31
1.9
1.9
—
—
—
0
0
7
52
1.35
0.31
1.3
1.6
—
—
—
0
0
18
147
1.22
0.30
1.1
1.2
—
33.75
—
0
8
557
5421
1.04
0.30
2.6
2.6
—
—
—
0
0
10
75
1.33
0.30
1.6
1.5
—
—
—
0
0
17
206
0.82
0.29
1.3
1.8
0.12
0.37
g/l
0.66
17
196
123
1307
0.93
0.28
2.7
2.3
31.60
33.43
u/l
0.27
102
1093
48
431
1.12
0.27
1.2
1.1
—
—
—
0
0
21
177
1.19
0.27
1.2
1.2
—
—
—
0
0
520
5067
1.04
0.26
2.5
2.4
—
—
—
0
0
54
592
0.91
0.26
1.4
1.5
—
—
—
0
0
78
721
1.08
0.26
2.6
2.5
0.72
0.71
ug/l
0.05
39
351
107
1003
1.07
0.25
2.0
1.9
1.26
1.25
g/l
0.05
101
950
9
75
1.20
0.25
1.4
1.3
—
—
—
0
0
21
179
1.17
0.24
1.2
1.2
—
—
—
0
0
9
76
1.18
0.24
1.4
1.1
—
—
—
0
0
6
83
0.72
0.24
1.2
1.2
—
—
—
0
0
52
474
1.10
0.24
1.2
1.3
2.52
4.68
u/ml
—
5
42
101
948
1.07
0.24
1.3
1.2
42.00
35.97
au/ml
—
6
47
46
504
0.91
0.23
2.6
2.1
2.57
3.87
iu/l
0.89
24
235
14
168
0.83
0.23
1.1
1.4
0.80
1.32
promille
0.90
14
132
31
275
1.13
0.22
1.7
1.6
—
—
—
0
0
16
189
0.84
0.22
2.9
1.7
—
—
—
0
0
26
228
1.14
0.22
1.4
1.4
—
—
—
0
0
20
231
0.86
0.22
1.2
1.7
6.64
7.28
g/l
1.27
20
226
10
79
1.27
0.22
2.0
1.8
—
—
—
0
0
40
362
1.11
0.21
2.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
6.4
—
—
—
0
0
202
2092
0.96
0.21
1.7
1.6
3.35
3.36
ratio
0.02
146
1459
6
49
1.22
0.20
1.3
1.6
—
—
—
0
0
6
49
1.22
0.20
3.7
4.1
2.08
1.31
%
—
6
49
51
470
1.09
0.20
1.2
1.3
4.25
11.65
u/ml
—
6
64
369
3774
0.97
0.20
2.6
2.4
—
—
—
0
0
64
596
1.07
0.19
1.6
1.7
9.31
8.89
u/ml
0.02
17
159
25
221
1.13
0.19
1.6
2.7
—
—
—
0
0
466
4748
0.97
0.19
4.0
3.4
30.26
29.67
u/l
0.13
446
4536
494
4836
1.03
0.19
1.8
1.8
1.30
1.31
mmol/l
0.11
451
4342
6
51
1.18
0.19
1.3
1.6
—
—
—
0
0
12
99
1.21
0.19
1.1
1.2
5.83
7.52
mm/h
0.87
12
99
12
99
1.21
0.19
1.1
1.5
1.59
1.47
nmol/l
0.14
12
89
74
694
1.07
0.19
1.3
1.2
2.73
4.98
—
9
82
149
1428
1.05
0.19
1.8
1.6
304.63
320.00
mu/l
0.28
130
1294
21
184
1.14
0.18
1.2
1.2
—
—
—
0
0
54
502
1.08
0.18
1.2
1.3
15.00
46.52
u/ml
—
8
20
76
716
1.06
0.17
1.1
1.1
0.61
0.62
ratio
—
5
56
21
185
1.13
0.17
1.2
1.2
—
—
—
0
0
18
205
0.88
0.17
1.2
1.6
9.04
10.31
g/l
0.45
18
199
18
205
0.88
0.17
1.7
1.4
—
—
—
0
0
11
91
1.21
0.17
1.5
3.1
32.19
23.74
ug/l
0.68
11
80
116
1108
1.05
0.17
2.8
3.2
33.67
32.28
%
0.59
90
838
131
1362
0.96
0.17
1.5
1.3
—
—
—
0
0
26
288
0.90
0.17
1.5
1.3
—
—
—
0
0
26
288
0.90
0.17
1.5
1.3
—
—
—
0
0
5
66
0.76
0.17
1.0
1.0
—
—
—
0
0
5
66
0.76
0.17
1.0
1.4
102.60
91.11
nmol/24h
—
5
66
32
291
1.10
0.17
1.2
1.3
1.50
5.35
u/ml
2.45
12
118
209
2025
1.03
0.16
1.6
1.5
450.73
30279755.06
pmol/l
2.01
176
1790
82
777
1.06
0.16
1.5
1.4
—
—
—
0
0
53
495
1.07
0.16
1.2
1.1
43.94
14.94
au/ml
0.37
11
113
11
92
1.19
0.15
1.1
1.2
363.18
87.92
u/l
0.43
11
80
79
749
1.06
0.15
1.1
1.1
1.51
1.52
g/l
0.21
79
749
80
759
1.05
0.15
1.1
1.1
0.82
0.86
g/l
0.77
80
759
392
3840
1.02
0.15
3.9
3.8
8.13
8.66
mmol/l
1.19
356
3481
17
192
0.88
0.15
1.3
1.6
0.00
0.02
g/l
0.50
17
185
45
420
1.07
0.14
1.2
1.3
47.78
41.64
u/ml
—
5
29
20
222
0.90
0.14
1.2
1.7
2.63
3.00
g/l
2.30
20
217
32
295
1.08
0.13
1.6
1.6
—
—
—
0
0
21
189
1.11
0.13
1.2
1.2
—
—
—
0
0
11
94
1.17
0.13
1.0
1.1
126.83
210.84
iu/ml
1.78
11
94
240
2345
1.03
0.12
1.6
1.6
1046.61
963.10
mu/l
0.81
216
2051
31
288
1.08
0.11
1.2
1.4
2.21
4.65
u/ml
1.49
14
140
73
699
1.04
0.11
1.3
1.4
—
—
—
0
0
10
86
1.16
0.10
1.1
1.1
—
—
—
0
0
38
402
0.94
0.10
2.7
2.4
683.46
662.15
e6/l
0.01
28
300
29
310
0.93
0.10
1.1
1.1
88.30
184.96
iu/ml
—
10
89
5
45
1.11
0.09
1.0
1.1
0.83
1.28
mom
—
5
45
230
2257
1.02
0.09
3.3
3.0
0.95
1.04
e6/l
0.19
112
1074
37
351
1.05
0.08
6.3
3.4
4.04
3.65
index
0.06
25
205
7
67
1.04
0.08
1.7
1.8
—
—
—
0
0
47
489
0.96
0.07
1.9
1.9
8.43
6.92
ug/l
0.29
42
422
60
578
1.04
0.07
4.2
2.8
5.11
6.19
umol/l
0.54
48
451
11
98
1.12
0.07
1.0
1.0
0.80
1.62
u/ml
0.37
11
98
8
78
1.02
0.07
1.8
1.4
—
82.78
%
—
0
9
8
78
1.02
0.07
1.9
2.2
—
—
—
0
0
38
397
0.95
0.07
2.7
2.4
8.36
12.72
e6/l
0.41
28
281
7
80
0.87
0.07
1.0
7.7
—
68.76
u/ml
—
0
21
15
163
0.92
0.07
1.0
1.3
0.42
0.50
nmol/l
1.06
15
156
242
2383
1.02
0.07
4.9
4.5
7.47
10.25
mg/mmol
0.67
163
1639
162
1645
0.98
0.06
1.4
1.5
3.24
3.32
mmol/l
0.39
107
1035
8
95
0.84
0.06
1.4
1.3
145.45
175.63
pmol/l
—
8
95
13
142
0.91
0.06
1.3
1.4
—
—
—
0
0
32
335
0.95
0.06
1.6
1.7
—
1728.00
—
0
10
12
131
0.91
0.06
1.0
1.1
—
—
—
0
0
17
158
1.07
0.06
8.6
3.5
53.27
102.23
u/ml
—
8
50
32
306
1.04
0.05
1.1
1.1
—
—
—
0
0
151
1489
1.01
0.04
1.5
1.5
—
—
—
0
0
326
3273
0.99
0.03
6.5
4.8
91.33
92.63
%
0.53
318
3199
55
560
0.98
0.03
1.7
1.9
—
—
—
0
0
330
3278
1.01
0.02
2.4
2.2
—
—
—
0
0
14
132
1.06
0.02
2.8
2.8
0.80
1.52
ratio
—
8
65
59
580
1.02
0.02
1.7
1.6
0.00
0.17
iu/ml
—
10
91
25
242
1.03
0.01
1.2
1.1
12.25
17.25
u/ml
—
8
90
14
133
1.05
0.01
1.0
1.0
10.49
19.04
u/ml
—
6
85
31
316
0.98
0.01
1.5
2.3
8.45
10.11
mg/l
0.91
31
299
32
313
1.02
0.01
1.5
1.7
7.24
7.55
mmol/l
0.45
32
301
11
104
1.06
0.00
1.1
1.2
—
—
—
0
0
1370
13671
1.00
0.00
16.0
13.9
334.38
333.67
g/l
2.22
1362
13571
21
204
1.03
0.00
1.2
1.2
—
—
—
0
0
14
143
0.98
0.00
2.1
2.1
11.63
20.76
umol/l
4.45
14
135
13
128
1.01
0.00
1.5
1.5
8.11
10.14
umol/l
1.63
13
122
250
2495
1.00
0.00
1.5
1.7
1.33
1.37
%
0.39
226
2251
15
145
1.03
0.00
1.5
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
95
1.05
0.00
1.1
1.2
—
—
—
0
0
155
1551
1.00
0.00
1.1
1.1
—
—
—
0
0
68
684
0.99
0.00
1.4
1.4
—
—
—
0
0
25
247
1.01
0.00
1.1
1.2
0.62
13.40
u/ml
1.02
11
102
10
98
1.02
0.00
1.0
1.2
—
—
—
0
0
70
695
1.01
0.00
1.3
1.3
—
—
—
0
0
5
55
0.91
0.00
1.0
1.1
—
—
—
0
0
5
55
0.91
0.00
1.2
1.1
83.20
85.35
u/l
—
5
50
0
5
0.00
-0.00
0.0
1.0
—
8.66
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
87.00
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
8048.17
—
0
6
5
49
1.02
-0.00
2.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
279.00
—
0
5
0
7
0.00
-0.00
0.0
5.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
428.88
—
0
8
0
5
0.00
-0.00
0.0
4.8
—
0.25
—
0
5
5
49
1.02
-0.00
2.0
1.1
—
32.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
715.80
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
0.00
—
0
7
0
6
0.00
-0.00
0.0
1.7
—
398.33
—
0
6
5
56
0.89
-0.00
1.2
1.1
—
—
—
0
0
5
54
0.92
-0.00
1.2
1.1
23.20
23.14
u/l
—
5
49
5
57
0.88
-0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
33.08
—
0
5
0
8
0.00
-0.00
0.0
2.1
—
15.95
—
0
8
8
89
0.90
-0.00
1.0
1.3
69.25
68.81
umol/l
—
8
89
0
5
0.00
-0.00
0.0
1.0
—
21.60
—
0
5
6
69
0.87
-0.00
1.3
2.4
1.58
1.92
nmol/l
—
6
64
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_HYPO_ONLY and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_HYPO_ONLY | 1.193 [0.89, 1.61] | 0.245 |
| Birth year | 0.992 [0.98, 1.0] | 0.07 |
During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 17984 females with K11_HYPO_ONLY died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_HYPO_ONLY | 0.962 [0.71, 1.31] | 0.805 |
| Birth year | 0.989 [0.98, 1.0] | 0.029 |
During the follow-up period (1.1.1998 — 31.12.2019), 57 out of 12761 males with K11_HYPO_ONLY died.
Mortality risk
Mortality risk for people of age
years, who have K11_HYPO_ONLY.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.111% | 0.2% |
| 5 | 0.683% | 1.062% |
| 10 | 1.67% | 2.862% |
| 15 | 2.925% | 5.365% |
| 20 | 5.103% | 9.419% |
Relationships between endpoints
↥Index endpoint: K11_HYPO_ONLY – Tooth agenesis EXCLUDE clefts and syndromes
GWS hits: 16
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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