Vascular syndromes of brain in cerebrovascular disorders

I9_VASCSYND

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G46*
  • Cause of death: ICD-10 G46*

2 out of 7 registries used, show all original rules.

1999

4. Check minimum number of events

None

1999

5. Include endpoints

None

1999

6. Filter based on genotype QC (FinnGen only)

1755

Control definitions (FinnGen only)

Control exclude
F5_DEMENTIA, G6_ALZHEIMER, G6_AD_STRICT

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1755 748 1007
Unadjusted period prevalence (%) 0.38 0.27 0.46
Median age at first event (years) 69.18 68.58 69.62

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1802
Matched controls
18020
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
9.1
307.7
820
1509
G46.3*I67.9
ICD-10 Finland
Brain stem stroke syndrome (I60-I67+)
6197.7
307.7
475
*
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
78.2
307.7
343
54
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
12.3
307.7
768
1030
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
9.0
307.7
503
740
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
+∞
307.7
683
*
N06DX01
ATC
memantine; oral
46.0
294.9
175
42
B01AC04
ATC
clopidogrel; oral
4.6
215.2
789
2617
N06DA02
ATC
donepezil; oral
39.5
214.7
132
36
G30.1
ICD-10 Finland
Alzheimer disease with late onset
44.4
214.5
128
31
AA1AD
NOMESCO Finland
CT of head and brain
4.3
202.9
1022
4231
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
7.4
189.3
303
478
G46.8*I67.9
ICD-10 Finland
Other vascular syndromes of brain in cerebrovascular diseases
383.4
176.7
175
5
N06DA03
ATC
rivastigmine; oral, transdermal
52.7
165.6
95
19
G46.7*I67.9
ICD-10 Finland
Other lacunar syndromes
+∞
162.0
153
*
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
7.7
159.2
239
349
G46.4
ICD-10 Finland
Cerebellar stroke syndrome
821.7
155.8
151
*
K90
ICPC
Stroke/cerebrovascular accident
7.7
141.9
212
307
F01.9
ICD-10 Finland
Vascular dementia, unspecified
48.9
128.7
75
16
R42
ICD-10 Finland
Dizziness and giddiness
3.3
124.4
730
3109
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
4.3
121.6
370
1020
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
51.0
110.8
64
13
G46.3
ICD-10 Finland
Brain stem stroke syndrome
+∞
108.4
103
*
F03
ICD-10 Finland
Unspecified dementia
12.2
105.0
107
93
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
4.1
101.4
320
899
XA800
NOMESCO Finland
Neuropsychological investigation
7.4
97.7
148
216
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
90.4
86
*
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
33.3
90.2
58
18
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
88.6
626
2858
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
7.1
87.9
138
209
P20
ICPC
Memory disturbance
3.3
86.5
407
1479
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
404.6
78.5
78
*
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
5.9
77.9
147
268
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.7
71.4
257
782
C10AA01
ATC
simvastatin; oral
2.3
65.4
1084
7072
G30.8
ICD-10 Finland
Other Alzheimer disease
104.0
64.3
70
7
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
7.1
63.6
98
145
C10AA05
ATC
atorvastatin; oral
2.3
63.5
1026
6590
N05AX08
ATC
risperidone; systemic
4.0
59.6
183
497
B01AC07
ATC
dipyridamole; systemic
3.5
59.1
225
707
I63.8
ICD-10 Finland
Other cerebral infarction
9.2
58.7
72
81
G46.8
ICD-10 Finland
Other vascular syndromes of brain in cerebrovascular diseases
575.7
56.9
56
*
G46.0*I66.0
ICD-10 Finland
Middle cerebral artery syndrome
+∞
54.4
52
*
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.0
54.3
266
972
315
Kela drug reimbursment
Clopidogrel
7.8
54.2
76
101
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.1
53.8
155
401
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
4.0
52.2
157
419
SPAT1053
SPAT
Memory test
2.5
50.3
388
1784
G46.5*I67.9
ICD-10 Finland
Pure motor lacunar syndrome
+∞
48.1
46
*
N06DA04
ATC
galantamine; oral
107.1
48.0
52
5
P70
ICPC
Dementia
9.8
47.9
56
59
B01AA03
ATC
warfarin; systemic
2.1
47.5
613
3493
K91
ICPC
Cerebrovascular disease
6.8
45.3
72
110
N18
ICPC
Paralysis/weakness
5.4
43.8
89
173
R53
ICD-10 Finland
Malaise and fatigue
2.1
42.4
526
2930
C10AX09
ATC
ezetimibe; oral
2.3
41.6
412
2097
G46.7
ICD-10 Finland
Other lacunar syndromes
+∞
40.8
39
*
I63
ICD-10 Finland
Cerebral infarction
8.5
39.9
52
63
AAL10
NOMESCO Finland
Intracranial endovascular thrombolysis
10.5
39.6
44
43
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
3.6
39.4
137
403
R51.80
ICD-10 Finland
Headache
2.4
38.7
294
1330
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
7.7
38.3
54
72
A28
ICPC
Limited function/disability NOS
2.1
37.6
482
2698
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
36.7
682
4340
SPAT1301
SPAT
No procedures
1.9
36.2
639
3993
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
35.9
1327
10504
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
8.6
35.7
46
55
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.8
34.4
185
705
G46.2*I66.2
ICD-10 Finland
Posterior cerebral artery syndrome
+∞
33.4
32
*
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.3
33.2
129
407
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.7
33.0
188
737
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
6.1
33.0
58
98
SPAT1216
SPAT
Assessment of functional ability
2.1
33.0
379
2026
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.7
32.8
190
752
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.9
32.5
591
3702
AAF00
NOMESCO Finland
Ventriculostomy
9.9
32.2
37
38
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.9
31.7
159
583
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.9
31.1
559
3478
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
30.3
432
2486
N02BE01
ATC
paracetamol; systemic, rectal
2.3
30.3
1592
13761
G46.6*I67.9
ICD-10 Finland
Pure sensory lacunar syndrome
+∞
29.2
28
*
205
Kela drug reimbursment
Chronic hypertension
1.8
28.8
702
4770
C09AA05
ATC
ramipril; oral
1.8
28.5
610
3985
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
4.2
28.5
76
185
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
28.4
355
1947
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
10.2
28.3
32
32
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.0
28.1
133
472
SPAT1229
SPAT
Assessment of need for aid
2.4
27.3
197
864
N03AG01
ATC
valproic acid; systemic, rectal
3.3
27.0
106
337
Z2445
NOMESCO Finland
Psychologist
4.2
26.1
70
171
G81.9
ICD-10 Finland
Hemiplegia, unspecified
6.6
26.1
42
65
I95.1
ICD-10 Finland
Orthostatic hypotension
2.9
25.4
121
430
F06.7
ICD-10 Finland
Mild cognitive disorder
3.7
25.4
83
234
AXX01
NOMESCO Finland
Memory assessment
9.8
25.0
29
30
C08CA01
ATC
amlodipine; oral
1.7
25.0
851
6265
N06AB10
ATC
escitalopram; oral
2.0
24.8
288
1532
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
4.4
24.7
62
144
S06.0
ICD-10 Finland
Concussion
2.3
24.2
210
997
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.8
24.1
126
471
G46.0
ICD-10 Finland
Middle cerebral artery syndrome
+∞
24.0
23
*
SPAT1254
SPAT
Administration of medicine
2.0
24.0
320
1787
PA6AD
NOMESCO Finland
CT of neck arteries
3.1
23.7
104
353
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.7
23.7
55
120
R41.0
ICD-10 Finland
Disorientation, unspecified
3.5
23.6
83
246
N05AH04
ATC
quetiapine; oral
2.1
23.4
249
1280
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
4.7
23.4
55
121
R20.2
ICD-10 Finland
Paraesthesia of skin
2.6
22.8
138
556
G44.2
ICD-10 Finland
Tension-type headache
2.1
22.7
230
1160
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
5.6
22.5
43
79
R1250
NOMESCO Finland
Evaluation of functional capability
4.1
22.5
62
155
SPAT1263
SPAT
Sampling
1.6
22.2
726
5243
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.1
21.9
92
304
N06AX11
ATC
mirtazapine; oral
1.7
21.8
580
3968
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
222.6
21.6
22
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.4
21.0
77
234
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
21.0
332
1954
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.8
20.6
109
410
G30
ICD-10 Finland
Alzheimer disease
212.4
20.6
21
*
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.2
20.4
180
859
SPAT1234
SPAT
Support of social functional capacity
2.6
20.3
124
502
A10AB05
ATC
insulin aspart; parenteral
2.3
20.0
169
792
G46.5
ICD-10 Finland
Pure motor lacunar syndrome
+∞
19.8
19
*
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
202.1
19.6
20
*
A10AE04
ATC
insulin glargine; parenteral
2.0
19.2
213
1109
C10AA07
ATC
rosuvastatin; oral
1.6
19.0
596
4218
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
5.9
18.9
34
59
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.3
18.8
158
738
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
18.7
343
2104
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.3
18.7
154
714
F01.30
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without additional symptoms
44.5
18.2
22
5
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
18.2
299
1773
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
20.3
17.7
26
13
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.9
17.7
249
1405
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
17.7
529
3689
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
17.6
261
1500
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
17.5
401
2614
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
7.4
17.4
25
34
OAB41
NOMESCO Finland
Guidance and counselling related to ageing
14.0
17.3
29
21
N03AX12
ATC
[U] gabapentin; oral
1.8
17.2
305
1849
J01DB01
ATC
cefalexin; oral
1.6
17.1
1373
11925
AA5PD
NOMESCO Finland
CT examination of brain pefusion
4.7
17.1
39
84
WX704
NOMESCO Finland
Intubation
2.2
17.0
155
749
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
4.3
16.7
43
102
N30.0
ICD-10 Finland
Acute cystitis
1.8
16.7
296
1793
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
16.7
518
3636
OAB76
NOMESCO Finland
General guidance on nutrition and food
35.4
16.7
21
6
AXX01, ,
SPAT
2.7
16.6
92
355
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.3
16.5
130
591
H53.4
ICD-10 Finland
Visual field defects
3.3
16.5
61
187
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.6
16.3
582
4214
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
16.1
291
1772
R41.3
ICD-10 Finland
Other amnesia
3.1
16.1
67
221
SPAT1252
SPAT
Overall medication plan or its review
2.1
16.0
156
773
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
16.0
636
4714
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.9
16.0
46
119
C07AB07
ATC
bisoprolol; oral
1.5
15.8
1022
8379
N19
ICPC
Speech disorder
4.5
15.7
38
86
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
15.6
937
7556
SPAT1101
SPAT
Orthostatic test
2.4
15.5
109
471
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
3.7
15.3
48
132
A10AC01
ATC
insulin (human); parenteral
2.0
15.3
173
906
G43.9
ICD-10 Finland
Migraine, unspecified
2.9
14.9
69
242
C03CA01
ATC
furosemide; systemic
1.5
14.9
771
6015
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.5
14.8
564
4125
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.9
14.8
189
1031
R55
ICD-10 Finland
Syncope and collapse
1.8
14.8
240
1414
F01.3
ICD-10 Finland
Mixed cortical and subcortical vascular dementia
151.2
14.5
15
*
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
5.8
14.5
26
45
G91.1
ICD-10 Finland
Obstructive hydrocephalus
12.7
14.4
25
20
PA6CG
NOMESCO Finland
Extensive MRI examination of neck vasculature with high intensity magnet
12.7
14.4
25
20
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
14.2
328
2131
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
14.2
569
4203
J01MA02
ATC
ciprofloxacin; systemic
1.5
14.1
724
5620
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.8
14.1
208
1190
C10AA03
ATC
pravastatin; oral
1.9
13.9
176
958
H53.2
ICD-10 Finland
Diplopia
2.6
13.7
78
305
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
13.7
525
3834
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
5.2
13.6
28
55
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
13.6
247
1502
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
13.6
13
*
R4120
NOMESCO Finland
Occupational therapy
2.1
13.5
124
600
XCK00
NOMESCO Finland
Perimetry
2.1
13.5
137
690
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
2.4
13.4
93
400
N28
ICPC
Limited function/disability (N)
3.6
13.4
44
125
F01.2
ICD-10 Finland
Subcortical vascular dementia
25.9
13.4
18
7
SPAT1304
SPAT
Counselling and guidance related to ageing
1.9
13.4
176
970
TAB00
NOMESCO Finland
Lumbar puncture
2.8
13.3
68
252
AN1
HP
Coronary angiography
1.7
13.3
275
1734
C09CA01
ATC
losartan; oral
1.5
13.2
506
3689
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.0
13.0
140
719
B01AB05
ATC
enoxaparin; parenteral
1.5
12.9
571
4288
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
3.1
12.6
51
166
SPAT1260
SPAT
Consultation of another employee
1.6
12.5
300
1962
N06AB04
ATC
citalopram; systemic
1.6
12.5
320
2129
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
12.4
509
3758
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
12.3
545
4083
WX720
NOMESCO Finland
Own respiration
2.3
12.3
98
448
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
2.8
12.2
62
229
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
12.2
298
1958
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.6
12.2
39
109
K89
ICPC
Transient cerebral ischaemia
3.9
12.1
35
91
WZC00, ,
SPAT
1.7
12.1
240
1494
SPAT1360
SPAT
Extensive global examination
2.1
12.1
122
613
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
12.1
239
1487
SPAT1285
SPAT
Provision of consultation response
2.2
12.0
99
459
N03AF02
ATC
oxcarbazepine; oral
2.8
12.0
60
220
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
4.0
11.9
33
83
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
11.9
300
1985
A06AD11
ATC
lactulose; oral
1.6
11.7
325
2201
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
11.7
446
3238
J01CA08
ATC
pivmecillinam; oral
1.5
11.6
572
4365
R47.1
ICD-10 Finland
Dysarthria and anarthria
3.9
11.6
33
85
SPAT1081
SPAT
Cardiorespiratory global assessment
2.0
11.5
123
630
F01.19
ICD-10 Finland
Multi-infarct dementia without information on additional symptoms
+∞
11.5
11
*
280
Kela drug reimbursment
Clopidogrel
2.9
11.4
52
181
G30.0
ICD-10 Finland
Alzheimer disease with early onset
120.8
11.4
12
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.3
11.4
42
129
SPAT1279
SPAT
Preparation of immediate hospitalisation
3.8
11.3
34
91
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.3
11.3
83
367
I69
ICD-10 Finland
Sequelae of cerebrovascular disease
8.9
11.3
23
26
R1430, ,
SPAT
3.7
11.2
35
96
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.3
11.2
89
406
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
11.2
706
5629
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
11.2
566
4336
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
11.2
277
1824
S70.0
ICD-10 Finland
Contusion of hip
2.3
11.2
86
388
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
10.9
398
2859
A01
ICPC
Pain general/multiple sites
1.8
10.8
181
1073
I20.01
ICD-10 Finland
Unstable angina
2.3
10.8
81
361
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
10.8
415
3012
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.7
10.7
235
1499
F05.9
ICD-10 Finland
Delirium, unspecified
2.9
10.7
49
171
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
10.7
232
1478
J01DA01
ATC
[U] cefalexin
1.4
10.6
1008
8589
WX892
NOMESCO Finland
Monitored bed care
1.8
10.6
157
898
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
10.6
149
839
R11
ICD-10 Finland
Nausea and vomiting
1.8
10.5
157
900
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.6
10.4
256
1680
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
3.7
10.4
32
87
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
110.7
10.4
11
*
SPAT1251
SPAT
Organisation of medication
2.2
10.1
80
365
SPAT1310
SPAT
Counselling related to known health issue
1.4
10.1
494
3746
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.1
10.1
41
134
L28
ICPC
Limited function/disability (L)
1.5
10.1
379
2734
-1, ,
ICPC
2.4
10.0
71
309
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
4.5
10.0
24
54
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
10.0
358
2555
C01DA14
ATC
isosorbide mononitrate; oral
1.5
10.0
420
3096
Z02.7
ICD-10 Finland
Issue of medical certificate
1.9
9.9
126
686
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.4
9.9
453
3391
N02AA05
ATC
oxycodone; systemic
1.5
9.9
372
2680
I50.0
ICD-10 Finland
Congestive heart failure
1.6
9.8
220
1410
A10AE05
ATC
insulin detemir; parenteral
2.0
9.8
100
504
P29
ICPC
Psychological sympt/compl other
2.3
9.8
76
344
N06AX21
ATC
duloxetine; oral
1.7
9.8
173
1042
M79.6
ICD-10 Finland
Pain in limb
1.4
9.7
678
5462
P76
ICPC
Depressive disorder
2.3
9.7
75
339
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.0
9.7
112
591
R47.0
ICD-10 Finland
Dysphasia and aphasia
3.6
9.7
31
87
A02BC02
ATC
pantoprazole; systemic
1.4
9.6
1165
10250
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
3.4
9.6
34
102
WVA20, ,
SPAT
2.3
9.6
72
322
Z75.5
ICD-10 Finland
Holiday relief care
4.6
9.5
22
48
SPAT1014
SPAT
Treatment of eyes
3.0
9.5
42
144
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
9.5
488
3728
N03AX16
ATC
[U] pregabalin
1.5
9.5
379
2763
F01.10
ICD-10 Finland
Multi-infarct dementia without additional symptoms
100.6
9.4
10
*
N06AA09
ATC
amitriptyline; systemic
1.7
9.4
168
1015
G464, I639,
ICD-10 Finland
+∞
9.4
9
*
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
+∞
9.4
9
*
G46.1*I66.1
ICD-10 Finland
Anterior cerebral artery syndrome
+∞
9.4
9
*
F0019, G301,
ICD-10 Finland
+∞
9.4
9
*
AA1ED
NOMESCO Finland
Trauma CT of head and neck
4.9
9.3
20
41
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
4.5
9.3
22
49
Z43.5
ICD-10 Finland
Attention to cystostomy
4.7
9.3
21
45
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
9.3
216
1398
E0000UV, ,
ATC
1.4
9.3
633
5073
H36.00
ICD-10 Finland
Diabetic background retinopathy
3.6
9.2
30
85
Z29
ICPC
Social problem NOS
3.1
9.2
37
120
WYA20
NOMESCO Finland
Home visit
3.0
9.2
40
136
W19
ICD-10 Finland
Unspecified fall
1.7
9.2
171
1044
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.8
9.2
44
158
OAB48
NOMESCO Finland
Lifestyle advice and guidance
13.7
9.2
15
11
A04
ICPC
Weakness/tiredness general
1.5
9.2
268
1830
KMAK, ,
NOMESCO Finland
1.4
9.1
671
5440
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
2.5
9.1
55
223
H25.1
ICD-10 Finland
Senile nuclear cataract
1.4
9.1
641
5162
A02BC03
ATC
lansoprazole; oral
1.4
9.0
503
3893
N05AH03
ATC
olanzapine; systemic
2.2
9.0
73
337
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.6
9.0
206
1329
SPAT1246
SPAT
Screening of depression or other psychiatric problem
3.0
8.9
39
133
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.1
8.9
86
426
SPAT1262
SPAT
Handing over of treatment supplies
1.5
8.9
304
2146
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
8.0
8.9
19
24
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
2.2
8.8
76
360
A10BA02
ATC
metformin; oral
1.4
8.8
540
4246
SPAT1097
SPAT
Recording of ECG
1.5
8.8
269
1855
4019X
ICD-9 Finland
Essential hypertension, Unspecified
2.1
8.8
79
381
A10AD05
ATC
insulin aspart; parenteral
2.6
8.7
49
192
N02BF01
ATC
gabapentin; oral
1.7
8.7
172
1069
C08CA13
ATC
lercanidipine; oral
1.5
8.7
286
2003
G04CA02
ATC
tamsulosin; oral
1.4
8.6
527
4139
J01EA01
ATC
trimethoprim; systemic
1.4
8.5
418
3161
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.4
8.5
643
5222
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
8.5
111
611
IHZ08
NOMESCO Finland
Provision of support and information for patient’s relatives
27.6
8.5
11
*
W0A10
NOMESCO Finland
Mapping of psychosocial situation
20.1
8.5
12
6
K78
ICPC
Atrial fibrillation/flutter
1.6
8.4
194
1253
M48.0
ICD-10 Finland
Spinal stenosis
1.5
8.4
250
1714
F009, G309,
ICD-10 Finland
+∞
8.3
8
*
G46.2
ICD-10 Finland
Posterior cerebral artery syndrome
+∞
8.3
8
*
G463, I639,
ICD-10 Finland
+∞
8.3
8
*
R13
ICD-10 Finland
Dysphagia
1.7
8.3
138
816
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.7
8.3
160
986
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.5
8.3
251
1724
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
2.2
8.3
72
342
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
1.7
8.3
148
894
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.8
8.2
132
773
C07AB02
ATC
metoprolol; systemic
1.4
8.2
425
3239
S01.0
ICD-10 Finland
Open wound of scalp
1.7
8.2
139
828
K22
ICPC
Risk factor cardiovascular disease
1.8
8.1
123
708
SPAT1240
SPAT
Therapeutic discussion
1.9
8.1
109
605
I67.8
ICD-10 Finland
Other specified cerebrovascular diseases
9.0
8.0
16
18
D07AA02
ATC
hydrocortisone; topical
1.6
8.0
199
1307
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.5
8.0
50
206
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.0
8.0
79
395
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.3
8.0
60
269
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.6
8.0
186
1204
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
8.0
453
3507
C10AA04
ATC
fluvastatin; oral
1.6
8.0
190
1237
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
2.6
7.9
45
177
A10AB01
ATC
insulin (human); parenteral
2.3
7.9
57
251
N01
ICPC
Headache
1.8
7.9
125
731
H13
ICPC
Plugged feeling ear
1.4
7.8
363
2711
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
7.8
194
1276
A10BB12
ATC
glimepiride; oral
1.7
7.7
159
997
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
7.7
660
5438
I66.0
ICD-10 Finland
Occlusion and stenosis of middle cerebral artery
45.2
7.7
9
*
OAB42, ,
SPAT
1.6
7.7
188
1231
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
3.4
7.7
27
81
SPAT1284
SPAT
Extensive health certificate
2.6
7.6
41
157
E86
ICD-10 Finland
Volume depletion
2.3
7.6
57
255
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
2.6
7.6
42
163
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.0
7.6
80
409
A10BH01
ATC
sitagliptin; oral
1.6
7.6
181
1177
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
2.4
7.6
51
218
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.4
7.6
479
3769
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
6.2
7.5
19
31
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
7.5
178
1156
C02AC05
ATC
moxonidine; oral
1.8
7.5
101
561
C08CA10
ATC
nilvadipine; oral
2.5
7.5
46
188
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.7
7.5
135
817
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
7.5
717
6000
U04
ICPC
Incontinence urine
1.8
7.5
112
644
SPAT1231
SPAT
Assessment of adjustments needed in living environment
2.6
7.5
41
159
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
3.1
7.4
30
98
S22.3
ICD-10 Finland
Fracture of rib
1.7
7.4
131
789
AAK80
NOMESCO Finland
Partial excision of skull cap
80.4
7.4
8
*
PA7CG
NOMESCO Finland
Extended MRI examination of vessesl in brain and neck with high intensity magnet
80.4
7.4
8
*
P03
ICPC
Feeling depressed
1.9
7.4
95
520
PA7CC
NOMESCO Finland
Very extensive angiography of arteries of neck and brain
13.4
7.4
12
9
-, ,
ICD-10 Finland
2.5
7.4
45
184
B01AE07
ATC
dabigatran etexilate; oral
1.9
7.3
83
436
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
7.3
526
4217
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
2.7
7.3
39
149
WZB00, ,
SPAT
1.8
7.3
107
611
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.4
7.3
377
2867
N29
ICPC
Neurological sympt/complt other
2.8
7.3
34
121
H34.1
ICD-10 Finland
Central retinal artery occlusion
3.9
7.3
21
55
UKC02
NOMESCO Finland
Cystoscopy
1.4
7.2
329
2446
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
7.2
616
5062
F05.1
ICD-10 Finland
Delirium superimposed on dementia
15.8
7.2
11
7
I67.0
ICD-10 Finland
Dissection of cerebral arteries, nonruptured
15.8
7.2
11
7
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.5
7.2
210
1430
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
5.8
7.2
19
33
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.4
7.2
358
2703
UJF32
NOMESCO Finland
Coloscopy
1.4
7.2
455
3575
I67.2
ICD-10 Finland
Cerebral atherosclerosis
4.5
7.2
17
38
N05CF01
ATC
zopiclone; oral
1.3
7.2
562
4562
WYA20, ,
SPAT
4.0
7.2
20
51
N06AX16
ATC
venlafaxine; oral
1.6
7.2
164
1057
J01DA09
ATC
[U] cefadroxil
1.4
7.1
387
2967
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
7.1
280
2028
G51.0
ICD-10 Finland
Bell palsy
2.4
7.1
48
206
G45
ICD-10 Finland
Transient cerebral ischaemic attacks and related syndromes
3.8
7.1
21
56
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
12.1
7.1
12
10
P01
ICPC
Feeling anxious/nervous/tense
1.8
7.1
94
521
A29
ICPC
General symptom/complaint other
1.5
7.0
233
1632
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
7.0
7.0
16
23
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
7.0
7.0
16
23
P05
ICPC
Senility, feeling/behaving old
4.4
7.0
17
39
I50.9
ICD-10 Finland
Heart failure, unspecified
1.4
6.9
376
2880
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.9
6.9
83
445
SPAT1244
SPAT
Occupational therapy
3.7
6.9
21
57
WX872
NOMESCO Finland
Intensive care
1.8
6.9
101
577
XF606
NOMESCO Finland
Ortostatic test
4.0
6.9
19
48
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.6
6.9
176
1165
M54.8
ICD-10 Finland
Other dorsalgia
2.0
6.9
68
341
C03AA03
ATC
hydrochlorothiazide; oral
1.6
6.9
184
1231
N03AX14
ATC
levetiracetam; systemic
2.4
6.8
47
203
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
2.3
6.8
48
210
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
2.5
6.8
41
167
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.2
6.8
54
249
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
6.8
123
748
N06AX26
ATC
vortioxetine; oral
1.9
6.7
76
399
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
6.7
251
1797
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.5
6.7
206
1418
C09DA01
ATC
losartan and diuretics; oral
1.5
6.7
197
1344
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
1.5
6.7
184
1237
NHQ40
NOMESCO Finland
Amputation of toe
2.5
6.6
41
169
207
Kela drug reimbursment
Chronic arrhythmias
1.4
6.6
366
2812
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.7
6.6
128
792
N06
ICPC
Sensation disturbance other
3.5
6.6
22
64
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
3.8
6.5
19
50
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
2.8
6.5
31
112
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.6
6.5
36
141
F01.39
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without information on additional symptoms
70.1
6.4
7
*
C09AA02
ATC
enalapril; systemic
1.4
6.4
391
3048
A10AA02, ,
ATC
2.0
6.4
64
322
L89
ICD-10 Finland
Decubitus ulcer and pressure area
2.4
6.4
43
184
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.5
6.4
174
1168
ZYC01
NOMESCO Finland
Remote contact by phone
1.8
6.4
88
494
N17
ICPC
Vertigo/dizziness
1.5
6.4
225
1594
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
6.4
220
1552
N05BA04
ATC
oxazepam; oral
1.4
6.3
376
2919
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.8
6.3
99
578
Z3229
NOMESCO Finland
Other healthcare associate professional
1.6
6.3
152
994
RP120, ,
NOMESCO Finland
+∞
6.3
6
*
F01.0
ICD-10 Finland
Vascular dementia of acute onset
+∞
6.3
6
*
G46.6
ICD-10 Finland
Pure sensory lacunar syndrome
+∞
6.3
6
*
F01.1
ICD-10 Finland
Multi-infarct dementia
+∞
6.3
6
*
XF404
NOMESCO Finland
Ambulatory ECG
1.6
6.2
158
1044
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
2.2
6.2
50
232
H02AB06
ATC
prednisolone; systemic
1.3
6.1
797
6891
R52.9
ICD-10 Finland
Pain, unspecified
1.6
6.1
154
1016
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.4
6.1
306
2310
A10AB04
ATC
insulin lispro; parenteral
2.3
6.1
45
201
Z00.0
ICD-10 Finland
General medical examination
1.4
6.1
299
2249
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
6.1
165
1107
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.6
6.1
124
778
H81.2
ICD-10 Finland
Vestibular neuronitis
2.4
6.1
39
164
SPAT1312
SPAT
General health counselling
1.3
6.1
443
3547
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
5.2
6.0
17
33
F43.00
ICD-10 Finland
Acute stress reaction mild
2.9
6.0
26
89

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
972
5141
2.93
108.88
2.8
2.2
189.48
213.99
u/l
0.43
926
4863
633
2732
3.03
101.74
2.1
2.0
28.80
29.95
s
3.14
618
2655
330
1156
3.27
73.60
7.2
6.6
24.64
24.41
mmol/l
0.43
321
1104
669
3441
2.50
71.48
6.3
4.4
1.03
1.02
kg/l
0.52
474
2343
365
1622
2.57
50.96
3.2
2.5
4.82
6.96
ug/l
1.59
332
1435
451
2243
2.35
48.98
6.9
7.4
5.08
5.09
kpa
0.09
436
2147
451
2244
2.35
48.92
6.9
7.4
11.40
11.80
kpa
1.10
436
2150
387
1829
2.42
46.97
7.3
8.2
119.55
118.98
g/l
0.22
378
1786
445
2245
2.30
46.44
7.0
7.4
7.41
7.41
ph
0.24
316
1233
443
2233
2.30
46.31
6.9
7.3
1.62
0.88
mmol/l
3.25
347
1830
1140
8226
2.05
45.38
27.4
20.3
1.48
1.37
inr
6.55
1000
6942
406
2000
2.33
44.61
7.0
7.7
95.40
95.33
%
0.07
391
1929
131
369
3.75
40.22
6.2
6.3
10.96
11.14
mmol/l
0.22
120
329
131
369
3.75
40.22
6.2
6.3
105.58
105.14
mmol/l
0.45
120
329
161
533
3.22
38.44
6.4
5.6
1.27
1.33
mmol/l
0.41
147
466
219
863
2.75
38.29
5.1
4.6
1.66
1.56
%
0.67
208
818
522
3026
2.02
36.91
1.8
1.8
1224.04
1179.56
nmol/l
0.57
433
2261
203
791
2.77
36.20
5.3
4.8
0.88
0.86
%
0.22
193
748
148
490
3.20
35.28
4.6
4.2
3.84
3.95
mmol/l
2.03
148
485
1216
9416
1.90
34.23
7.0
5.3
7.06
6.86
mmol/l
2.69
1174
9016
910
6468
1.82
33.53
6.0
4.4
43.56
83.03
ng/l
1.61
745
5133
218
917
2.57
33.28
3.5
3.4
25.59
25.16
mmol/l
1.01
208
884
260
1198
2.37
32.53
3.5
3.1
127.34
126.46
g/l
0.25
255
1165
369
1984
2.08
31.45
3.9
3.7
7.38
7.38
ph
0.35
231
1182
768
5260
1.80
31.35
4.6
3.5
—
—
—
0
0
358
1908
2.09
31.22
4.5
3.7
1.92
1.88
mmol/l
0.07
313
1626
368
1984
2.07
31.11
3.8
3.6
5.88
5.84
kpa
0.37
358
1925
350
1854
2.10
31.00
12.5
8.1
—
—
—
0
0
1332
10778
1.90
30.82
35.5
26.4
330.78
331.18
g/l
0.85
1320
10699
318
1652
2.12
29.53
3.5
3.0
4.60
4.47
kpa
0.45
308
1599
671
4501
1.78
28.74
6.1
4.3
0.00
0.00
estimate
0.78
136
1587
740
5177
1.73
26.86
4.8
4.6
—
—
—
0
0
814
5851
1.71
26.73
6.0
4.3
0.04
0.73
estimate
0.82
117
1470
214
1012
2.26
24.91
3.3
2.6
0.67
0.61
%
2.55
214
1006
966
7390
1.66
24.15
5.9
5.3
34.35
34.55
g/l
0.50
911
6908
60
142
4.34
23.35
1.1
1.2
—
—
—
0
0
1019
7955
1.65
23.08
5.9
4.2
0.00
3.46
estimate
1.33
158
1810
707
5050
1.66
22.67
4.4
4.5
7.40
7.40
ph
0.02
559
3685
1021
8004
1.64
22.49
5.9
4.2
0.00
0.01
estimate
1.29
142
1687
1054
8332
1.64
22.42
9.4
7.8
1.20
1.21
mmol/l
2.30
977
7139
1228
10097
1.68
22.31
6.6
5.3
430.68
1685.94
e6/l
1.29
22
161
969
7511
1.63
22.24
8.1
6.9
1.19
1.21
mmol/l
4.89
936
6918
511
3434
1.68
20.25
5.1
4.5
213.97
396.41
ng/l
1.67
444
2991
992
7852
1.59
19.93
5.8
4.2
0.00
0.00
estimate
0.50
147
1764
212
1098
2.05
19.41
9.4
9.6
15.87
15.61
%
0.73
203
1058
826
6305
1.57
19.14
5.4
3.7
6.47
6.27
ph
4.79
474
3440
75
244
3.16
18.39
1.5
1.3
7.42
75.75
e6/l
1.23
60
179
75
248
3.11
17.90
1.5
1.4
1873.89
883.42
e6/l
0.38
62
194
919
7304
1.53
17.00
2.4
2.2
93.28
94.56
pmol/l
0.35
541
3861
81
294
2.84
16.41
1.3
1.3
546.52
660.24
mg/l
1.14
75
282
121
538
2.34
16.17
2.0
1.9
20.27
21.11
s
1.44
93
487
74
260
2.93
15.91
1.3
1.3
4.12
3.84
mmol/l
1.00
67
241
54
157
3.51
15.84
1.3
1.2
5.95
8.53
u/ml
0.29
21
72
905
7245
1.50
15.67
3.2
3.0
—
—
estimate
—
0
0
278
1706
1.74
14.89
6.4
7.3
1.43
1.35
mmol/l
0.45
273
1669
269
1653
1.74
14.31
3.6
3.3
222.34
268.08
ng/l
1.05
253
1521
1515
13679
1.68
14.14
27.1
20.0
27.75
27.95
mg/l
0.08
1356
11663
658
5026
1.49
13.83
3.0
2.6
56.17
61.06
u/l
0.56
621
4636
1212
10440
1.49
13.67
4.3
4.2
15.24
15.07
pmol/l
1.46
1128
9399
265
1650
1.71
13.40
7.4
8.6
—
—
—
0
0
476
3426
1.53
13.21
1.8
1.8
434.81
22444327.63
pmol/l
2.38
429
2807
29
61
4.82
13.09
1.1
1.2
1.05
1.08
ratio
0.73
23
48
211
1252
1.78
12.62
8.5
9.5
93.75
93.93
%
0.17
211
1244
1308
11579
1.47
11.73
8.4
8.9
82.56
83.16
u/l
0.11
1257
10954
290
1926
1.60
11.29
2.1
1.8
—
—
—
0
0
598
4622
1.44
11.28
2.8
2.4
3.15
2.99
mg/l
0.78
539
3989
39
118
3.36
10.84
2.3
2.2
—
—
—
0
0
1547
14258
1.60
10.80
33.8
24.5
139.71
139.49
mmol/l
2.48
1527
13981
632
4966
1.42
10.76
1.8
1.8
18.85
19.93
nmol/l
0.96
571
4156
1548
14273
1.60
10.75
33.8
24.7
4.02
4.01
mmol/l
0.57
1525
13978
991
8455
1.38
10.15
6.0
6.9
12.08
12.61
umol/l
0.54
950
8091
743
6058
1.39
9.99
4.1
3.4
1941.55
1848.70
ng/l
0.21
679
5352
687
5531
1.39
9.97
3.2
3.7
2.34
2.35
mmol/l
1.91
625
4946
321
4431
0.66
9.79
3.7
3.6
—
—
—
0
0
58
239
2.47
9.26
1.5
1.3
—
—
—
0
0
1386
12605
1.43
9.14
5.8
5.3
1.96
2.05
mu/l
1.69
1313
11427
1557
14502
1.54
8.93
34.8
26.9
88.50
85.07
umol/l
2.03
1541
14308
783
6525
1.35
8.84
2.6
2.4
77.52
79.39
nmol/l
1.15
715
5728
443
3377
1.41
8.61
3.4
3.2
2.46
2.47
mmol/l
0.21
401
2999
1227
10987
1.37
8.44
30.4
24.9
14.14
13.93
%
4.86
1213
10821
21
50
4.24
8.20
1.2
1.2
0.60
0.49
ratio
0.67
16
30
335
2458
1.45
7.98
6.7
5.8
1.04
1.04
mmol/l
0.06
312
2292
85
439
1.98
7.86
12.7
12.6
—
—
—
0
0
60
1214
0.48
7.60
5.3
4.3
—
—
—
0
0
253
1779
1.49
7.47
7.0
6.7
11.23
11.68
mmol/l
0.32
241
1703
1557
14612
1.48
7.46
39.7
30.1
239.28
240.63
e9/l
0.33
1536
14272
1557
14614
1.48
7.44
39.5
30.0
91.50
91.79
fl
1.67
1543
14410
1557
14615
1.48
7.43
39.6
30.1
4.35
4.39
e12/l
2.01
1532
14223
1557
14615
1.48
7.43
39.5
30.0
30.32
30.44
pg
1.91
1543
14411
1557
14615
1.48
7.43
40.3
30.7
39.27
39.58
%
1.40
1543
14402
1557
14617
1.48
7.40
39.6
30.1
7.23
6.97
e9/l
4.24
1532
14222
1557
14617
1.48
7.40
39.9
30.3
130.83
132.53
g/l
4.10
1543
14423
1428
13200
1.39
7.39
8.5
7.3
42.56
40.38
mmol/mol
11.96
1372
12184
134
2121
0.60
7.39
1.5
1.4
—
—
—
0
0
137
842
1.68
7.22
2.0
1.9
1.28
1.81
ug/l
0.30
123
749
1197
10796
1.32
7.10
5.2
4.6
14.97
14.60
mm/h
0.30
1146
10016
21
61
3.47
6.29
1.1
1.0
1001.36
837.29
ng/l
0.61
14
41
21
61
3.47
6.29
1.1
1.0
270.79
222.56
ng/l
0.57
14
43
1520
14316
1.39
6.07
14.7
13.4
26.98
25.15
u/l
0.53
1487
13831
544
4491
1.30
5.95
5.9
6.7
—
—
—
0
0
88
1455
0.58
5.74
1.5
1.4
—
—
—
0
0
486
3977
1.30
5.62
3.0
2.9
4.43
4.93
e6/l
0.52
458
3647
668
5695
1.27
5.61
3.7
3.5
52.97
47.70
mg/l
0.27
489
3778
682
5832
1.27
5.58
4.1
4.2
9.81
9.05
mg/mmol
0.21
480
3731
875
7709
1.26
5.57
6.3
6.1
0.04
0.04
e9/l
0.76
780
6482
675
5778
1.27
5.44
3.6
3.4
7.16
7.16
mmol/l
0.02
611
4809
65
350
1.89
5.42
1.6
2.6
28.52
34.84
umol/l
1.49
57
312
871
7686
1.26
5.41
6.3
6.1
0.63
0.62
e9/l
0.30
775
6450
8
310
0.25
5.36
1.1
1.3
—
—
—
0
0
195
1391
1.45
5.34
4.6
3.9
108.37
100.70
ng/l
0.42
178
1188
1367
12744
1.30
5.30
5.2
4.6
1.31
1.28
mmol/l
0.80
1296
11468
85
501
1.73
5.28
1.2
1.2
0.30
0.98
u/ml
0.65
13
34
389
3119
1.32
5.18
3.2
2.7
10.67
12.04
umol/l
4.04
370
2917
68
379
1.83
5.11
1.2
1.2
—
—
—
0
0
760
6633
1.25
5.10
3.7
3.2
129.84
152.11
ug/l
2.38
713
6107
36
160
2.28
5.00
1.4
1.3
8276.41
157486.77
e6/l
1.48
22
103
961
8629
1.24
4.93
9.1
9.7
4.61
4.30
e9/l
3.02
875
7423
401
3252
1.30
4.88
2.1
1.7
1.39
1.52
mg/l
0.32
319
2550
9
10
9.04
4.78
1.1
1.1
—
—
—
0
0
877
7817
1.24
4.75
6.4
6.2
1.85
1.89
e9/l
0.19
791
6751
888
7929
1.24
4.72
6.4
6.3
0.20
0.20
e9/l
0.18
804
6791
241
1840
1.36
4.45
2.2
2.6
67.83
68.41
e9/l
0.12
193
1368
562
4809
1.25
4.33
3.2
3.2
31.76
35.40
u/l
1.08
531
4522
110
1605
0.66
4.18
5.1
4.9
7.30
7.36
ph
1.20
91
1154
44
228
1.95
4.17
1.2
1.5
—
—
—
0
0
44
228
1.95
4.17
1.2
1.5
—
—
—
0
0
44
228
1.95
4.17
1.2
1.5
—
—
—
0
0
44
228
1.95
4.17
1.2
1.5
—
—
—
0
0
513
5955
0.81
4.06
2.2
2.4
—
—
—
0
0
124
856
1.48
4.06
2.4
2.6
18.13
18.39
au/ml
—
7
70
1441
13661
1.27
4.05
7.5
6.3
2.19
2.53
mmol/l
43.92
1387
12470
295
2354
1.30
4.01
2.1
2.5
1.75
1.81
%
0.54
268
2105
358
2933
1.28
3.97
3.3
3.1
0.82
0.81
mmol/l
0.05
334
2764
14
43
3.27
3.91
1.1
1.0
1621.79
1425.81
miu/ml
0.19
14
43
483
4111
1.24
3.84
4.2
4.4
79.56
83.67
%
2.66
470
4020
75
473
1.61
3.70
3.4
2.7
62.82
59.56
%
0.58
69
457
958
8753
1.20
3.65
3.4
3.4
54.77
57.80
u/l
0.36
898
8090
166
1241
1.37
3.53
3.5
2.8
6.04
6.04
ph
0.01
127
902
631
5569
1.20
3.44
4.1
3.7
63.75
83.00
e6/l
0.47
540
4378
1408
13409
1.23
3.24
6.3
5.8
6.27
6.10
mmol/l
4.18
1323
12076
21
448
0.46
3.23
1.1
1.2
—
—
—
0
0
1393
13263
1.22
3.15
6.0
5.4
1.35
1.43
mmol/l
10.89
1332
12054
34
181
1.90
3.06
1.3
1.5
53.64
62.94
%
0.60
22
118
33
592
0.55
3.01
1.7
1.9
2.90
3.43
mmol/l
1.22
20
441
26
127
2.06
2.97
1.3
1.4
27.56
28.10
%
0.03
17
79
1400
13364
1.21
2.94
6.3
5.5
4.02
4.42
mmol/l
40.81
1347
12268
301
2502
1.24
2.92
2.3
2.1
—
—
—
0
0
11
32
3.45
2.90
1.5
1.3
—
—
—
0
0
9
22
4.11
2.88
13.4
15.5
5.90
5.10
mmol/l
—
9
22
74
499
1.50
2.80
3.6
3.3
1.57
1.62
mmol/l
0.24
74
485
17
72
2.37
2.72
1.7
1.2
146.76
140.44
nmol/l
0.19
17
72
320
3757
0.82
2.66
3.0
3.6
0.85
0.85
ug/l
0.02
226
2642
25
126
2.00
2.66
1.7
1.6
—
—
—
0
0
346
2950
1.21
2.63
3.3
2.7
2.29
2.24
g/l
0.97
334
2726
22
106
2.09
2.63
1.1
1.1
—
—
—
0
0
588
5260
1.17
2.61
3.0
2.7
—
—
—
0
0
76
530
1.45
2.47
3.4
3.5
0.80
0.83
nmol/l
0.21
64
434
213
1740
1.25
2.43
2.8
2.8
66.35
66.09
g/l
0.20
200
1603
7
189
0.37
2.41
1.9
1.3
—
—
—
0
0
16
71
2.26
2.34
1.5
1.8
296.82
280.76
mu/l
0.13
11
51
672
6124
1.16
2.28
4.8
4.3
99.83
116.82
e6/l
0.33
539
4512
59
855
0.68
2.26
5.6
4.0
—
—
—
0
0
17
339
0.50
2.24
3.6
3.2
59.47
59.77
%
0.04
17
339
92
678
1.38
2.22
1.4
1.3
—
—
—
0
0
5
9
5.57
2.21
1.0
1.0
—
—
—
0
0
73
518
1.43
2.19
1.4
1.5
—
—
—
0
0
9
30
3.01
2.14
43.1
7.2
5.49
5.06
kpa
—
9
30
319
2753
1.19
2.13
3.4
2.7
19.20
21.73
%
3.43
304
2574
189
1548
1.25
2.12
2.1
2.1
0.00
0.02
estimate
0.78
38
302
453
4029
1.17
2.11
3.0
2.6
—
—
—
0
0
52
348
1.51
2.11
1.1
1.2
—
—
—
0
0
12
49
2.46
2.10
1.2
1.3
137.71
161.91
mmol/24h
0.60
12
49
41
627
0.65
2.07
2.7
3.1
191.47
390.30
mg/l
1.31
21
280
9
31
2.91
2.07
1.1
1.0
—
—
—
0
0
9
31
2.91
2.07
1.2
1.1
—
—
—
0
0
484
4337
1.16
2.04
3.3
3.1
363.97
362.64
umol/l
0.09
422
3736
60
417
1.45
2.03
3.7
3.5
8.15
7.65
mmol/l
0.56
60
405
527
5809
0.87
1.99
4.7
4.1
—
0.65
—
0
20
51
738
0.68
1.98
1.2
1.2
—
—
—
0
0
432
3847
1.16
1.97
1.2
1.3
—
—
—
0
0
21
112
1.89
1.96
1.9
1.3
—
—
—
0
0
281
2418
1.19
1.94
1.3
1.3
62.48
36.78
iu/ml
0.51
90
751
346
3032
1.17
1.94
3.6
3.2
2.76
1.18
e6/l
1.00
229
1697
101
774
1.32
1.93
2.1
2.0
—
—
—
0
0
30
180
1.68
1.92
1.3
1.3
0.18
0.20
nmol/l
0.49
25
142
65
465
1.41
1.90
1.4
1.6
—
—
—
0
0
33
204
1.63
1.89
1.4
1.3
0.66
0.68
nmol/l
0.15
33
192
24
407
0.58
1.89
3.9
2.7
16.38
15.95
%
0.23
24
401
7
23
3.05
1.80
1.3
2.5
1.86
2.70
%
—
7
23
7
166
0.42
1.79
1.0
1.2
—
—
—
0
0
58
412
1.42
1.78
2.2
2.4
148.77
80.66
ug/min
0.40
26
243
15
285
0.52
1.76
3.1
3.2
4.64
4.60
e9/l
0.02
15
285
15
75
2.01
1.69
5.4
1.7
1671.80
116.04
e6/l
0.46
15
70
60
434
1.40
1.68
1.6
1.6
18990.18
15217.09
e6/l
0.19
45
302
22
126
1.76
1.68
4.0
3.5
71.07
30.76
mg/l
0.34
16
105
34
220
1.56
1.65
2.6
2.1
—
—
—
0
0
28
174
1.62
1.61
1.4
1.3
—
—
nmol/l
—
0
0
21
121
1.74
1.58
1.4
1.2
—
—
—
0
0
79
604
1.32
1.58
1.5
1.2
—
—
—
0
0
165
1384
1.21
1.53
2.3
2.2
357.63
382.97
nmol/l
1.03
143
1271
0
42
0.00
1.52
0.0
1.0
—
7.53
—
0
5
7
27
2.60
1.51
1.0
1.1
—
—
—
0
0
7
27
2.60
1.51
2.1
1.3
25.29
27.63
s
—
7
27
526
4829
1.13
1.50
3.8
3.6
0.51
0.51
e6/l
0.01
437
3673
170
1434
1.20
1.50
2.7
2.5
—
—
—
0
0
35
234
1.51
1.50
21.3
6.6
7.97
7.22
mmol/l
0.62
30
197
345
3087
1.15
1.47
5.9
5.0
—
—
—
0
0
21
124
1.70
1.47
1.8
2.3
8.81
7.59
mmol/l
0.67
21
124
101
1253
0.79
1.46
4.7
3.8
5.08
5.15
kpa
0.24
96
1206
98
1220
0.79
1.46
4.7
3.9
7.42
7.42
ph
0.15
86
1022
96
763
1.27
1.46
2.3
3.3
4.12
4.36
pmol/l
1.88
86
675
12
59
2.04
1.43
1.5
1.1
35.20
185.81
ng/l
—
5
16
445
4057
1.13
1.42
3.9
3.3
0.10
0.08
—
10
151
144
1202
1.22
1.42
9.2
9.0
24.21
24.23
mmol/l
0.03
138
1169
16
276
0.58
1.40
1.9
2.7
—
—
—
0
0
10
46
2.18
1.40
4.1
1.6
29.50
32.70
%
—
10
46
121
995
1.23
1.39
1.4
1.8
1.51
1.54
g/l
0.14
111
868
11
210
0.52
1.36
5.5
4.3
57.91
58.99
%
0.06
11
183
5
17
2.95
1.36
1.0
1.3
64.40
64.76
ug/l
—
5
17
5
17
2.95
1.36
1.4
1.0
—
—
—
0
0
15
82
1.84
1.35
4.7
1.8
0.65
0.62
e9/l
0.08
15
77
44
604
0.72
1.34
1.5
1.4
—
—
—
0
0
0
38
0.00
1.34
0.0
2.7
—
—
—
0
0
30
201
1.50
1.30
2.1
1.3
64.45
65.31
mu/l
0.01
30
177
115
1385
0.82
1.29
4.3
4.0
1.23
1.22
mmol/l
0.30
106
1205
446
4090
1.12
1.29
4.7
3.8
2.16
0.04
estimate
0.48
116
1371
5
18
2.78
1.28
1.2
1.1
—
—
—
0
0
22
138
1.60
1.26
1.6
1.2
—
—
—
0
0
209
1832
1.16
1.21
3.5
3.2
4.53
4.89
e9/l
0.45
187
1550
42
306
1.38
1.20
1.3
1.4
—
—
—
0
0
12
64
1.88
1.18
1.5
1.4
57.83
79.57
umol/l
—
6
37
33
463
0.71
1.18
1.3
1.2
—
7.40
—
0
6
89
724
1.24
1.16
1.6
1.5
—
12.41
—
0
19
5
20
2.50
1.15
1.4
2.4
—
33.42
—
0
6
189
1654
1.16
1.13
2.0
2.2
0.20
0.20
g/l
0.61
179
1536
13
220
0.59
1.11
1.2
1.2
—
—
—
0
0
49
639
0.76
1.11
5.8
4.0
23.74
24.85
mmol/l
1.93
44
590
16
96
1.67
1.10
1.2
1.2
10.51
9.04
mmol/l
0.67
16
89
16
97
1.66
1.06
1.3
1.5
57.73
67.66
%
0.37
11
83
255
2293
1.13
1.04
1.3
1.3
5.13
13.00
u/ml
1.88
108
816
72
581
1.25
1.03
1.9
1.7
6.23
7.65
iu/ml
0.15
29
137
13
76
1.72
0.99
1.5
1.7
17.85
17.18
nmol/l
0.09
13
67
152
1325
1.16
0.98
1.5
1.5
—
—
—
0
0
21
306
0.68
0.96
3.1
1.9
1.43
1.66
mmol/l
1.46
21
297
32
433
0.73
0.96
3.2
4.2
—
—
—
0
0
0
32
0.00
0.95
0.0
2.8
—
—
—
0
0
6
117
0.51
0.94
1.5
1.3
—
—
—
0
0
17
257
0.66
0.93
1.5
1.2
0.76
0.91
g/l
1.75
17
257
57
454
1.26
0.93
1.9
2.3
128.00
126.58
g/l
0.15
45
356
8
146
0.55
0.92
1.0
1.1
—
—
—
0
0
8
146
0.55
0.92
1.0
1.1
—
—
—
0
0
152
1723
0.87
0.89
1.2
1.3
—
—
—
0
0
12
71
1.69
0.89
8.4
1.4
83.57
60.54
mg/l
—
7
50
12
71
1.69
0.89
3.6
3.5
—
—
—
0
0
49
386
1.28
0.88
1.3
1.4
65.14
58.76
mmol/l
0.53
42
310
27
194
1.40
0.88
1.3
1.4
278.00
274.27
mosm/kgh2o
0.33
22
146
7
129
0.54
0.88
2.1
2.5
—
—
—
0
0
135
1183
1.15
0.84
3.1
2.8
10.38
10.97
g/l
0.59
126
1084
33
249
1.33
0.82
1.6
1.3
—
—
—
0
0
14
89
1.58
0.81
1.4
1.5
17.31
15.73
umol/l
0.20
14
82
19
130
1.47
0.81
1.3
1.2
3.50
2.79
g/l
0.68
14
95
19
130
1.47
0.81
1.3
1.2
7.18
7.28
g/l
0.04
14
96
19
130
1.47
0.81
1.3
1.2
0.65
0.45
g/l
0.61
14
96
14
212
0.66
0.80
2.4
2.3
1.49
0.50
mmol/l
0.30
14
205
0
25
0.00
0.79
0.0
2.9
—
0.74
—
0
25
41
323
1.28
0.76
1.4
1.8
3.02
4.16
iu/l
0.86
11
125
19
132
1.44
0.76
1.3
1.2
—
—
—
0
0
143
1270
1.14
0.75
1.6
1.5
—
—
—
0
0
9
53
1.70
0.75
2.7
2.6
0.65
0.60
mmol/l
—
9
53
59
487
1.22
0.74
4.0
3.7
1.44
1.90
index
0.42
32
258
9
56
1.61
0.72
1.2
1.2
—
—
—
0
0
24
321
0.74
0.71
2.0
2.1
0.83
0.89
%
0.27
17
233
5
26
1.93
0.70
1.0
1.1
—
—
—
0
0
305
2839
1.09
0.69
1.3
1.3
2.80
1.56
u/ml
0.62
99
741
17
239
0.71
0.69
1.1
1.2
1.52
1.52
g/l
0.01
17
239
659
6316
1.07
0.68
5.4
6.2
2.91
4.36
ug/l
1.06
612
5664
206
1882
1.11
0.68
1.5
1.5
—
—
—
0
0
200
1828
1.11
0.66
1.4
1.3
309.09
561.45
titre
4.03
44
414
29
223
1.31
0.66
1.4
1.3
153.86
159.18
au/ml
—
7
62
19
260
0.73
0.66
1.5
1.7
19.76
19.42
ug/l
0.03
19
255
13
86
1.52
0.66
1.5
1.6
—
—
—
0
0
16
225
0.71
0.65
1.4
1.3
—
—
—
0
0
24
180
1.34
0.65
3.8
3.5
18.71
11.16
index
1.05
14
94
18
247
0.73
0.64
1.2
1.8
—
—
—
0
0
5
29
1.73
0.64
1.2
1.5
—
—
—
0
0
13
188
0.69
0.62
1.5
1.2
—
—
—
0
0
58
489
1.19
0.62
1.6
1.5
253.87
271.44
ug/g
0.28
40
309
11
71
1.55
0.62
1.4
2.2
1488.27
1336.03
u/ml
0.07
11
71
8
49
1.64
0.62
1.4
1.3
—
—
—
0
0
113
1267
0.88
0.61
1.4
1.6
—
—
—
0
0
9
140
0.64
0.60
1.0
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.6
—
—
—
0
0
14
197
0.71
0.59
2.6
2.6
—
—
—
0
0
87
989
0.87
0.58
1.2
1.2
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
15.00
—
0
11
167
1526
1.10
0.58
2.0
2.2
153.39
142.63
ug/g
0.13
145
1197
15
106
1.42
0.57
1.2
1.6
—
—
—
0
0
5
88
0.57
0.56
1.0
1.1
—
—
—
0
0
158
1446
1.10
0.54
1.6
1.5
—
—
—
0
0
9
132
0.68
0.52
1.4
1.3
—
—
—
0
0
363
3445
1.07
0.51
3.7
3.2
520.18
529.38
mosm/kgh2o
0.39
332
3029
6
40
1.50
0.51
1.3
1.3
—
—
—
0
0
75
851
0.88
0.51
1.3
1.4
—
—
—
0
0
25
197
1.27
0.51
1.2
1.1
21.40
13.62
iu/ml
—
5
31
20
153
1.31
0.50
1.3
1.2
—
—
—
0
0
172
1860
0.92
0.50
2.2
2.7
7.39
10.08
umol/l
1.84
151
1669
22
171
1.29
0.50
1.1
1.6
20.13
32.22
ng/l
0.91
22
171
634
6556
0.95
0.49
13.6
13.0
0.01
0.00
e9/l
0.44
531
5307
16
119
1.35
0.48
2.2
2.5
17.36
16.42
%
0.45
16
119
19
244
0.78
0.47
1.1
1.2
—
—
—
0
0
5
31
1.61
0.43
1.0
1.1
—
—
—
0
0
6
91
0.66
0.42
1.2
1.6
90.83
93.10
umol/l
—
6
91
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
99
901
1.10
0.41
2.6
2.5
—
—
—
0
0
88
797
1.11
0.40
2.9
2.8
—
—
—
0
0
7
103
0.68
0.39
1.7
1.1
—
—
—
0
0
5
35
1.43
0.39
4.0
4.0
—
—
—
0
0
7
106
0.66
0.39
2.3
2.3
2.23
2.07
ug/l
—
7
88
0
19
0.00
0.39
0.0
1.1
—
111.16
—
0
19
0
19
0.00
0.39
0.0
1.0
—
7.90
—
0
11
21
169
1.25
0.38
1.6
2.0
—
—
—
0
0
9
68
1.33
0.37
1.7
1.6
—
—
—
0
0
59
662
0.89
0.37
1.2
1.3
—
—
—
0
0
9
69
1.31
0.37
1.2
1.4
10.81
21.22
umol/l
—
9
61
83
911
0.91
0.36
5.6
3.8
1.02
1.02
ratio
0.10
76
832
31
263
1.18
0.36
2.5
2.4
—
—
—
0
0
13
168
0.77
0.35
1.4
1.3
—
—
—
0
0
6
46
1.31
0.33
1.0
1.4
—
—
—
0
0
143
1523
0.93
0.32
2.5
2.5
31.98
39.17
u/l
1.26
128
1270
31
358
0.86
0.31
3.7
3.7
23.68
30.22
mg/l
0.53
23
251
136
1446
0.94
0.30
6.0
4.5
0.05
0.12
%
1.12
41
445
203
2131
0.95
0.30
1.3
1.3
—
—
—
0
0
26
222
1.17
0.29
1.3
1.5
0.78
0.88
g/l
0.30
21
176
18
217
0.83
0.29
1.1
1.0
—
—
—
0
0
8
109
0.73
0.29
2.0
2.3
3.21
3.10
ug/l
—
8
102
7
57
1.23
0.29
2.3
4.5
64.07
55.60
%
—
7
52
74
804
0.92
0.28
1.2
1.3
130.32
232.24
u/ml
1.88
66
737
11
85
1.30
0.28
2.9
3.1
—
—
—
0
0
8
62
1.29
0.28
1.0
1.3
—
0.05
—
0
5
8
63
1.27
0.27
1.9
1.3
—
—
—
0
0
170
1616
1.06
0.27
1.8
1.6
—
—
—
0
0
77
711
1.09
0.27
1.1
1.2
56.59
131.43
u/ml
2.07
26
264
8
66
1.21
0.26
4.3
3.6
—
—
—
0
0
14
113
1.24
0.26
1.2
1.1
—
—
—
0
0
13
104
1.25
0.26
3.8
2.2
75.83
118.17
ug/min
—
6
23
5
73
0.68
0.26
1.0
1.2
—
—
—
0
0
118
1252
0.94
0.25
2.8
2.3
11.87
12.65
nmol/l
0.48
103
1097
41
456
0.90
0.25
1.1
1.1
—
—
—
0
0
12
96
1.25
0.24
1.0
1.0
—
—
—
0
0
144
1515
0.95
0.24
5.7
4.5
0.84
0.90
%
0.12
49
512
15
124
1.21
0.24
1.5
1.6
86.38
108.20
ng/l
1.03
15
124
14
115
1.22
0.23
2.4
2.3
11.90
46.86
iu/ml
—
5
17
51
466
1.10
0.23
1.5
1.6
55.31
25.04
u/ml
—
7
89
23
264
0.87
0.23
1.8
1.5
—
—
—
0
0
707
7190
0.97
0.22
6.5
6.4
0.63
0.65
%
0.72
663
6708
7
93
0.75
0.22
1.7
1.1
—
—
—
0
0
52
477
1.09
0.22
6.3
4.6
—
—
—
0
0
5
41
1.22
0.22
1.0
3.2
511.40
691.63
ug/l
—
5
41
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
6
49
1.23
0.20
1.2
1.1
—
—
—
0
0
6
49
1.23
0.20
1.2
1.1
—
—
—
0
0
6
49
1.23
0.20
1.2
1.1
—
—
—
0
0
6
50
1.20
0.19
2.3
1.6
181.23
124.22
ug/l
—
6
44
10
81
1.24
0.18
1.1
1.2
141.20
358.19
u/l
—
10
74
36
394
0.91
0.18
1.2
1.2
120.00
102.50
titre
—
5
36
208
2016
1.04
0.17
3.3
4.2
11.98
24.74
ug/l
1.00
180
1694
17
148
1.15
0.17
1.5
1.4
—
—
—
0
0
37
402
0.92
0.16
1.2
1.2
—
661.00
—
0
10
34
311
1.10
0.16
1.6
1.5
967.68
4548.99
e6/l
0.69
25
217
8
68
1.18
0.16
2.6
1.6
—
—
—
0
0
139
1444
0.96
0.16
6.3
4.7
0.46
0.16
%
0.36
39
413
27
298
0.90
0.16
2.0
1.8
186.63
206.55
pmol/l
0.58
27
280
16
139
1.15
0.16
1.5
1.4
—
—
—
0
0
13
111
1.17
0.15
1.6
1.4
—
—
—
0
0
12
102
1.18
0.15
2.0
1.7
—
—
—
0
0
12
139
0.86
0.14
2.0
2.3
608.83
650.80
ml
—
6
88
711
7189
0.98
0.13
6.5
6.3
2.74
2.83
%
0.55
665
6715
139
1434
0.97
0.13
5.5
4.4
0.48
0.68
%
1.37
46
479
722
7294
0.98
0.12
6.6
6.4
24.99
25.77
%
1.12
676
6881
28
258
1.09
0.12
1.4
1.4
6.66
6.55
mmol/l
0.07
28
245
713
7202
0.98
0.12
6.5
6.4
9.26
9.19
%
0.25
666
6725
45
424
1.06
0.12
2.7
3.3
611.70
1059.97
u/ml
0.27
39
393
275
2800
0.98
0.11
4.1
3.3
3.02
1.75
e6/l
1.36
158
1459
15
167
0.90
0.10
1.0
1.1
—
—
—
0
0
77
741
1.04
0.10
2.7
2.6
9.82
10.58
g/l
0.59
70
664
17
154
1.10
0.10
1.8
2.0
0.75
1.44
u/field
—
8
79
45
473
0.95
0.09
2.2
1.6
0.24
0.32
mg/l
0.55
21
211
10
114
0.88
0.09
1.0
1.1
—
—
—
0
0
37
391
0.95
0.09
1.2
1.1
—
—
—
0
0
255
2592
0.98
0.09
1.5
1.5
2.45
2.67
g/l
1.00
166
1555
37
351
1.06
0.08
1.5
1.6
—
—
—
0
0
27
253
1.07
0.08
1.3
1.3
10.02
9.47
u/l
0.11
20
195
70
724
0.97
0.08
2.8
3.2
6356.23
6050.84
u/ml
0.02
61
624
25
234
1.07
0.08
2.4
2.2
1.68
1.46
g/24h
0.14
11
138
93
956
0.97
0.08
2.2
1.8
1.17
1.48
g/l
0.80
87
865
9
85
1.06
0.07
1.0
1.0
—
—
—
0
0
31
295
1.05
0.06
1.3
1.2
52.54
55.43
u/ml
—
5
32
33
345
0.96
0.06
1.4
1.6
—
—
—
0
0
29
277
1.05
0.05
1.6
1.4
152437.37
86386.12
e6/l
0.24
16
154
16
149
1.07
0.05
1.5
1.3
—
—
—
0
0
16
149
1.07
0.05
1.4
1.3
—
—
—
0
0
16
149
1.07
0.05
1.5
1.3
—
—
—
0
0
25
262
0.95
0.04
1.7
1.5
—
—
—
0
0
67
685
0.98
0.04
3.6
3.3
15.10
4.33
ratio
0.44
49
410
18
190
0.95
0.04
7.1
4.7
—
—
—
0
0
12
129
0.93
0.03
1.1
1.2
103.25
96.59
pmol/l
0.16
12
129
78
767
1.02
0.03
1.9
2.2
7.14
1.18
estimate
0.38
35
213
538
5371
1.00
0.01
5.7
6.1
—
—
—
0
0
714
7132
1.00
0.00
6.5
6.3
59.25
58.73
%
0.54
678
6800
25
256
0.98
0.00
1.8
1.7
—
—
—
0
0
578
5774
1.00
0.00
2.0
1.9
1.34
1.31
mmol/l
0.17
527
4757
12
119
1.01
0.00
1.9
1.5
1863.92
1789.10
ml
0.12
12
114
22
219
1.00
0.00
1.2
1.2
341.08
288.11
u/ml
0.30
12
119
94
945
0.99
0.00
1.2
1.3
—
—
—
0
0
16
156
1.03
0.00
1.1
1.1
—
—
—
0
0
22
224
0.98
0.00
1.1
1.1
—
—
—
0
0
31
314
0.99
0.00
1.0
1.1
—
—
—
0
0
10
103
0.97
0.00
2.0
1.8
—
—
—
0
0
29
293
0.99
0.00
1.2
1.2
—
—
—
0
0
40
397
1.01
0.00
1.6
2.0
14.24
12.48
mg/l
0.58
35
362
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
332.38
—
0
8
0
5
0.00
0.00
0.0
2.0
—
2.24
—
0
5
5
50
1.00
0.00
1.6
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.3
—
389.50
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.07
—
0
6
6
62
0.97
-0.00
1.0
1.2
93.87
164.86
pmol/l
—
6
62
5
56
0.89
-0.00
1.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: I9_VASCSYND – Vascular syndromes of brain in cerebrovascular disorders

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).