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Use of levodopa decarbox-comt-inhibitor

PDMED_LEVODOPA_DECARBOX_COMTINHIBITOR

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC N04BA03

1 out of 7 registries used, show all original rules.

1320

4. Check minimum number of events

Min. number of events 3
1320

5. Include endpoints

None

1320

6. Filter based on genotype QC (FinnGen only)

1183

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1183 433 750
Unadjusted period prevalence (%) 0.27 0.15 0.34
Median age at first event (years) 70.14 69.04 70.77

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1206
Matched controls
12060
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N04BC09
ATC
rotigotine; transdermal
251.2
307.7
225
11
G20
ICD-10 Finland
Parkinson disease
4190.5
307.7
1188
187
N87
ICPC
Parkinsonism
196.4
307.7
665
75
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
2259.3
307.7
1181
247
193
Kela drug reimbursment
Rasagiline
625.6
307.7
463
12
AAG20
NOMESCO Finland
Stereotactic intracranial implantation of electrodes
210.0
307.7
179
10
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
179.5
307.7
308
23
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
+∞
307.7
1206
13
N04BC04
ATC
ropinirole; oral
254.6
307.7
487
32
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
3741.8
307.7
1184
171
N06DA03
ATC
rivastigmine; oral, transdermal
13.6
307.7
394
415
N04BB01
ATC
amantadine; oral
46.1
307.7
229
61
N04BD01
ATC
selegiline; oral
357.7
307.7
749
55
N04BC05
ATC
pramipexole; oral
33.1
307.7
746
564
N04BD02
ATC
rasagiline; oral
656.9
307.7
562
16
N04BX02
ATC
entacapone; oral
528.3
299.2
286
7
N05AH04
ATC
quetiapine; oral
7.4
254.1
521
1118
N03AE01
ATC
clonazepam; systemic
10.3
220.4
280
345
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
65.1
193.6
107
18
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
26.3
171.7
121
51
R25.1
ICD-10 Finland
Tremor, unspecified
10.3
144.3
172
191
N04AA02
ATC
biperiden; systemic
18.4
142.6
117
70
XA800
NOMESCO Finland
Neuropsychological investigation
10.0
139.1
170
195
G04BD12
ATC
mirabegron; oral
4.7
129.8
405
1176
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
211.5
129.4
132
7
H02AA02
ATC
fludrocortisone; oral
19.1
111.4
89
50
N04BC06
ATC
cabergoline; oral
49.4
104.7
61
13
N19
ICPC
Speech disorder
14.4
102.5
95
71
R1250
NOMESCO Finland
Evaluation of functional capability
9.7
102.3
125
142
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
20.8
101.6
78
40
N04BX04
ATC
opicapone; oral
158.0
84.2
88
6
R4130
NOMESCO Finland
Speech therapy
8.2
82.7
115
153
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
12.1
80.0
82
72
SPAT1229
SPAT
Assessment of need for aid
4.3
79.2
236
641
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
4.8
74.1
188
449
L28
ICPC
Limited function/disability (L)
3.0
69.9
447
1967
Z2445
NOMESCO Finland
Psychologist
7.8
67.8
97
133
A06AD11
ATC
lactulose; oral
3.1
66.6
371
1504
AA1AD
NOMESCO Finland
CT of head and brain
2.8
66.5
600
3153
A28
ICPC
Limited function/disability NOS
2.9
64.7
445
2023
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.7
62.4
590
3147
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
20.8
60.2
46
23
R53
ICD-10 Finland
Malaise and fatigue
2.8
59.7
451
2137
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.0
59.2
349
1449
I95.1
ICD-10 Finland
Orthostatic hypotension
4.6
57.4
149
360
F02.39
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
202.9
56.5
58
*
G02CB01
ATC
bromocriptine; systemic
16.8
55.8
47
29
D21
ICPC
Swallowing problem
8.7
54.8
71
86
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
4.7
51.8
129
301
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.5
51.2
197
630
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.6
50.3
129
308
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.6
49.6
429
2138
SPAT1231
SPAT
Assessment of adjustments needed in living environment
6.6
48.5
81
131
SPAT1215
SPAT
Assessment of need for medical rehabilitation
5.0
48.0
109
235
N29
ICPC
Neurological sympt/complt other
7.2
47.5
72
105
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.9
47.4
88
158
C07AA05
ATC
propranolol; systemic
2.8
46.9
296
1257
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.7
46.2
304
1318
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.7
45.2
313
1391
N06AX11
ATC
mirtazapine; oral
2.4
45.2
512
2859
N04BC02
ATC
pergolide; oral
122.2
44.1
47
*
S01.0
ICD-10 Finland
Open wound of scalp
3.2
43.6
197
692
SPAT1216
SPAT
Assessment of functional ability
2.6
43.0
334
1566
XF606
NOMESCO Finland
Ortostatic test
11.1
42.8
46
43
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.6
41.0
146
441
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.4
40.1
160
520
JDB10
NOMESCO Finland
Percutaneous gastrostomy
8.0
39.8
55
72
N05BA04
ATC
oxazepam; oral
2.3
37.8
401
2144
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.2
36.7
472
2724
R5110, ,
SPAT
2.9
35.7
196
765
R1260
NOMESCO Finland
Evaluation of communicative skills
5.9
35.5
65
115
R47.1
ICD-10 Finland
Dysarthria and anarthria
7.6
35.4
51
70
Z50.5
ICD-10 Finland
Speech therapy
9.8
35.2
41
43
U04
ICPC
Incontinence urine
3.2
35.1
150
507
N30.0
ICD-10 Finland
Acute cystitis
2.5
35.0
258
1167
N06AB10
ATC
escitalopram; oral
2.6
34.8
246
1090
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.5
34.8
266
1224
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.9
34.2
187
727
SPAT1234
SPAT
Support of social functional capacity
3.4
33.9
133
426
R35
ICD-10 Finland
Polyuria
2.9
32.5
166
621
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.0
32.4
154
553
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.8
32.0
176
685
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
8.3
30.9
41
51
N04BC07
ATC
apomorphine; parenteral
+∞
30.3
29
*
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
60.0
30.2
35
6
N28
ICPC
Limited function/disability (N)
5.3
30.2
62
122
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
5.1
30.1
64
130
W19
ICD-10 Finland
Unspecified fall
2.6
28.7
185
779
AA5EN
NOMESCO Finland
Brain reseptor or transprot protein distribution isotope imaging
29.3
27.7
37
13
S72.0
ICD-10 Finland
Fracture of neck of femur
3.3
27.3
111
363
F0230, G20,
ICD-10 Finland
+∞
27.2
26
*
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
6.7
26.1
42
65
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
25.8
279
1470
G04BD09
ATC
trospium; oral
4.5
25.8
64
148
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
7.5
25.5
37
51
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.0
25.0
73
191
N03AX12
ATC
[U] gabapentin; oral
2.2
24.9
254
1306
F02.30
ICD-10 Finland
Dementia in Parkinson's disease without additional symptoms
255.2
24.8
25
*
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
4.2
24.2
65
160
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
7.6
23.8
34
46
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
23.8
266
1415
AAW01
NOMESCO Finland
Implantation of intracranial stimulation device
+∞
23.0
22
*
K59.09
ICD-10 Finland
Constipation, unspecified
2.6
23.0
144
596
G04BD08
ATC
solifenacin; oral
2.7
22.9
136
548
Z3226
NOMESCO Finland
Physiotherapist
2.1
22.8
276
1512
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.1
22.7
97
326
R4130, ,
SPAT
27.9
22.3
30
11
M48.0
ICD-10 Finland
Spinal stenosis
2.1
22.2
237
1236
R13
ICD-10 Finland
Dysphagia
2.6
22.2
139
575
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.6
21.3
136
567
RF120, ,
NOMESCO Finland
6.6
21.0
34
53
J01EA01
ATC
trimethoprim; systemic
1.9
20.9
330
1975
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.6
20.7
125
507
F0232, G20,
ICD-10 Finland
112.0
20.6
22
*
G23.9
ICD-10 Finland
Degenerative disease of basal ganglia, unspecified
22.8
20.4
29
13
N05AH02
ATC
clozapine; systemic
7.6
20.4
29
39
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
5.5
20.0
39
73
F02.32
ICD-10 Finland
Dementia in Parkinson's disease other additional symptoms, mainly hallucinations
106.8
19.6
21
*
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
4.0
19.5
56
145
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
19.0
167
803
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.6
18.6
110
441
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.3
18.6
71
223
R32
ICD-10 Finland
Unspecified urinary incontinence
3.7
18.4
59
165
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.2
18.3
73
235
AA1AA
NOMESCO Finland
Head X-ray examination
6.2
18.2
31
51
G04BD11
ATC
fesoterodine; oral
3.5
18.1
63
186
N30.9
ICD-10 Finland
Cystitis, unspecified
2.6
17.9
106
425
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.8
17.9
93
349
R23
ICPC
Voice symptom/complaint
4.6
17.9
43
97
N04BA07
ATC
foslevodopa and decarboxylase inhibitor; parenteral
+∞
17.7
17
*
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
37.3
17.6
22
6
N04BC01
ATC
bromocriptine; oral
96.5
17.6
19
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.3
17.1
133
606
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.7
17.1
95
369
G25.2
ICD-10 Finland
Other specified forms of tremor
7.3
17.0
25
35
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
3.2
17.0
68
220
M41.9
ICD-10 Finland
Scoliosis, unspecified
5.8
16.9
31
55
K08.3
ICD-10 Finland
Retained dental root
2.3
16.7
133
612
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
5.0
16.7
36
74
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
16.6
16.6
26
16
J01CA08
ATC
pivmecillinam; oral
1.7
16.3
388
2600
S01.1
ICD-10 Finland
Open wound of eyelid and periocular area
3.5
16.2
57
170
K59.0
ICD-10 Finland
Constipation
2.5
16.2
102
422
S01.41
ICD-10 Finland
Open wound in the temple-jaw region
5.7
16.1
30
54
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
14.7
15.9
26
18
A04
ICPC
Weakness/tiredness general
1.9
15.7
226
1298
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
15.7
209
3434
RF420, ,
NOMESCO Finland
5.0
15.5
33
67
AA5QN, ,
NOMESCO Finland
162.0
15.5
16
*
N99
ICPC
Neurological disease other
4.8
15.5
35
75
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.4
15.5
55
165
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
6.8
15.3
24
36
Z75.5
ICD-10 Finland
Holiday relief care
5.7
15.1
28
50
SPAT1297
SPAT
Other function in accordance with speech therapy nomenclature
14.2
15.1
25
18
S70.0
ICD-10 Finland
Contusion of hip
2.8
14.9
77
288
SPAT1244
SPAT
Occupational therapy
6.0
14.8
26
44
K02.1
ICD-10 Finland
Caries of dentine
1.6
14.8
614
4713
SPAT1254
SPAT
Administration of medicine
1.9
14.6
221
1290
F02.34
ICD-10 Finland
Dementia in Parkinson's disease, other additional symptoms of mixed type
151.8
14.5
15
*
R33
ICD-10 Finland
Retention of urine
2.0
14.1
167
896
N03AX16
ATC
[U] pregabalin
1.7
13.9
299
1934
N86
ICPC
Multiple sclerosis
17.8
13.9
21
12
UKC02
NOMESCO Finland
Cystoscopy
1.7
13.8
280
1782
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.2
13.3
120
580
R1430, ,
SPAT
4.7
13.1
30
65
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.2
13.0
34
82
UDQ42
NOMESCO Finland
Endoscopic assessment of swallowing function
16.9
13.0
20
12
S01.8
ICD-10 Finland
Open wound of other parts of head
4.0
13.0
36
91
H02AB06
ATC
prednisolone; systemic
0.6
13.0
332
4635
RF410, ,
NOMESCO Finland
5.1
12.9
27
54
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
3.0
12.9
56
190
S62.3
ICD-10 Finland
Fracture of other metacarpal bone
3.6
12.9
42
119
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.0
12.8
138
716
NF1AA
NOMESCO Finland
Hip X-ray examination
2.0
12.7
156
846
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.6
12.6
41
116
R41.0
ICD-10 Finland
Disorientation, unspecified
2.7
12.4
67
257
M54.5
ICD-10 Finland
Low back pain
1.6
12.3
404
2895
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
5.9
12.3
22
38
R4120, ,
SPAT
4.3
12.2
31
73
K03.66
ICD-10 Finland
Tooth plaque
2.2
12.1
108
520
XKD00
NOMESCO Finland
Uroflowmetry
1.7
12.0
290
1924
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
3.4
12.0
43
130
U07
ICPC
Urine symptom/complaint other
2.0
11.8
130
678
G35
ICD-10 Finland
Multiple sclerosis
5.9
11.8
21
36
SFA10
NOMESCO Finland
One-surface restoration
1.5
11.6
575
4503
R1250, ,
SPAT
2.9
11.6
54
191
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.7
11.6
64
248
F05.9
ICD-10 Finland
Delirium, unspecified
3.1
11.6
48
159
N02BE01
ATC
paracetamol; systemic, rectal
1.9
11.6
1074
9748
L75
ICPC
Fracture: femur
4.1
11.4
31
77
S22.3
ICD-10 Finland
Fracture of rib
2.1
11.4
118
602
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
0.3
11.3
39
1102
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.7
11.3
248
1602
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
10.7
11.3
21
20
ZXH01
NOMESCO Finland
Procedure performed within operation theatre
35.4
11.3
14
*
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.7
11.2
59
223
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
3.0
11.2
48
162
S06.0
ICD-10 Finland
Concussion
1.9
11.2
145
801
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
11.2
229
1453
SPAT1167
SPAT
Insertion of urinary catheter
2.5
11.1
68
278
XKC03
NOMESCO Finland
Water cystometry
2.9
11.1
52
185
R1420, ,
SPAT
10.2
11.0
21
21
R4110, ,
SPAT
1.8
10.9
186
1120
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
10.9
399
2918
A03FA01
ATC
metoclopramide; systemic, rectal
0.5
10.8
98
1856
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
3.6
10.8
35
99
Z3231
NOMESCO Finland
Registered nurse
1.6
10.8
339
2393
130
Kela drug reimbursment
Malignant tumour
0.3
10.7
26
883
EBA00
NOMESCO Finland
Extraction of tooth
1.5
10.7
410
3024
SPAT1172
SPAT
Guidance concerning hydration
3.1
10.7
44
145
G90.3
ICD-10 Finland
Multi-system degeneration
21.7
10.7
15
7
R60.0
ICD-10 Finland
Localized oedema
1.8
10.7
189
1150
N06AX21
ATC
duloxetine; oral
1.9
10.6
135
742
N04BX01
ATC
tolcapone; oral
111.0
10.4
11
*
G21.8
ICD-10 Finland
Other secondary parkinsonism
32.8
10.3
13
*
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
8.9
10.3
21
24
3320A
ICD-9 Finland
Parkinson's disease, Paralysis agitans
23.6
10.2
14
6
R44.1
ICD-10 Finland
Visual hallucinations
7.5
10.2
23
31
R1100, ,
SPAT
4.2
9.9
26
63
N30
ICD-10 Finland
Cystitis
2.2
9.9
83
390
S63.1
ICD-10 Finland
Dislocation of finger
4.0
9.9
28
72
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
9.9
193
1206
I10
ICD-10 Finland
Essential (primary) hypertension
0.7
9.8
627
7411
N02AA05
ATC
oxycodone; systemic
1.6
9.7
294
2051
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.8
9.6
47
171
S01
ICD-10 Finland
Open wound of head
4.1
9.5
26
65
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
2.4
9.5
63
267
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
9.5
653
5382
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
3.4
9.5
34
103
L84
ICD-10 Finland
Corns and callosities
2.6
9.5
55
219
SPAT1304
SPAT
Counselling and guidance related to ageing
1.9
9.5
125
694
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
9.4
53
208
N87
ICD-10 Finland
Dysplasia of cervix uteri
+∞
9.4
9
*
N06AB04
ATC
citalopram; systemic
1.6
9.3
233
1550
C10AX09
ATC
ezetimibe; oral
0.5
9.3
86
1625
H02AB02
ATC
dexamethasone; systemic
0.3
9.2
34
932
R4110
NOMESCO Finland
Physiotherapy
1.5
9.2
342
2491
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
1.7
9.2
165
1006
WYA20
NOMESCO Finland
Home visit
3.0
9.2
41
142
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.7
9.1
160
970
M03BX01
ATC
baclofen; systemic
3.3
9.1
33
101
SCA02
NOMESCO Finland
Preventive oral health care
2.0
9.1
94
480
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
9.1
769
6574
TJD10
NOMESCO Finland
Insertion of other tube into stomach or duodenum
15.7
9.0
14
9
AA1AM
NOMESCO Finland
Short MRI examination of brain with 3 Tesla magnet
37.0
9.0
11
*
I95.9
ICD-10 Finland
Hypotension, unspecified
3.1
9.0
37
122
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.1
9.0
24
59
W06
ICD-10 Finland
Fall involving bed
4.2
8.9
23
55
SPAT1050
SPAT
Extensive neurological examination
3.2
8.8
35
113
TKC22
NOMESCO Finland
Catheterisation instruction
2.7
8.8
48
185
L03AA13
ATC
pegfilgrastim; parenteral
0.1
8.8
*
281
N08
ICPC
Abnormal involuntary movements
10.8
8.8
16
15
C10AA07
ATC
rosuvastatin; oral
0.6
8.7
217
3125
N04AA01
ATC
trihexyphenidyl; oral
50.4
8.7
10
*
SPAT1301
SPAT
No procedures
1.5
8.7
387
2921
R2110
NOMESCO Finland
Giving the first information
2.3
8.6
66
299
SPAT1262
SPAT
Handing over of treatment supplies
1.6
8.6
240
1638
WX402
NOMESCO Finland
General anaesthesia
1.6
8.6
247
1698
M41.5
ICD-10 Finland
Other secondary scoliosis
16.4
8.6
13
8
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
8.5
193
1253
F0234, G20,
ICD-10 Finland
90.7
8.4
9
*
N06AX16
ATC
venlafaxine; oral
1.8
8.4
131
766
AA052, ,
NOMESCO Finland
+∞
8.3
8
*
F02.3
ICD-10 Finland
Dementia in Parkinson disease
+∞
8.3
8
*
N02BF01
ATC
gabapentin; oral
1.8
8.3
129
753
H50.31
ICD-10 Finland
Intermittent exotropia
8.6
8.3
17
20
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.8
8.3
120
686
T08
ICPC
Weight loss
3.1
8.3
33
107
R4120
NOMESCO Finland
Occupational therapy
2.1
8.3
83
419
R4190
NOMESCO Finland
Nutritional therapy
2.5
8.2
49
198
N40
ICD-10 Finland
Hyperplasia of prostate
1.5
8.1
403
3096
M04AA01
ATC
allopurinol; systemic
0.5
8.1
79
1471
G23.1
ICD-10 Finland
Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
11.8
8.1
14
12
E86
ICD-10 Finland
Volume depletion
2.5
8.1
48
194
K86
ICPC
Hypertension uncomplicated
0.5
8.1
67
1316
RF210, ,
NOMESCO Finland
2.7
8.1
41
153
R5599
NOMESCO Finland
Other rehabilitation service
2.6
7.9
44
172
S72.1
ICD-10 Finland
Pertrochanteric fracture
2.5
7.8
47
191
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.5
7.8
282
2033
RF214, ,
NOMESCO Finland
45.3
7.7
9
*
IBC97
NOMESCO Finland
Other psychiatric aptitude assessment
45.3
7.7
9
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
0.2
7.7
6
341
L76
ICPC
Fracture: other
2.5
7.7
47
193
SCA03
NOMESCO Finland
Preventive oral health care, extensive
2.5
7.7
47
193
G04CB01
ATC
finasteride; oral
1.6
7.6
205
1384
G24.9
ICD-10 Finland
Dystonia, unspecified
11.9
7.6
13
11
3010
Kela drug reimbursment
Midodrine
25.2
7.6
10
*
K11.72
ICD-10 Finland
Xerostomia
25.2
7.6
10
*
R5130, ,
SPAT
8.9
7.6
15
17
OAB43, ,
SPAT
0.3
7.5
18
617
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
3.1
7.5
31
103
Y94.0
ICD-10 Finland
Accident at home
3.1
7.5
30
98
WX212
NOMESCO Finland
Femoral plexus blockade
2.6
7.4
43
172
Z29
ICPC
Social problem NOS
3.0
7.4
31
104
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.1
7.3
64
307
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
7.3
130
790
F02.31
ICD-10 Finland
Dementia in Parkinson's disease other additional symptoms, mainly paranoidism
+∞
7.3
7
*
F023, G20,
ICD-10 Finland
+∞
7.3
7
*
M41.4
ICD-10 Finland
Neuromuscular scoliosis
+∞
7.3
7
*
H50.52
ICD-10 Finland
Exophoria
4.2
7.3
19
46
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
2.0
7.3
80
418
S00.0
ICD-10 Finland
Superficial injury of scalp
2.6
7.2
41
162
M79.6
ICD-10 Finland
Pain in limb
1.4
7.2
479
3858
C01CA17
ATC
midodrine; oral
30.2
7.2
9
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.2
7.1
27
85
G23.8
ICD-10 Finland
Other specified degenerative diseases of basal ganglia
20.1
7.1
10
5
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
7.1
503
4093
Z43.5
ICD-10 Finland
Attention to cystostomy
4.1
7.1
19
47
R55
ICD-10 Finland
Syncope and collapse
1.6
7.0
159
1030
S01.9
ICD-10 Finland
Open wound of head, part unspecified
3.0
7.0
29
97
R63.4
ICD-10 Finland
Abnormal weight loss
2.1
6.9
66
328
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.9
320
2417
K04.1
ICD-10 Finland
Necrosis of pulp
1.8
6.8
109
642
SPAT1127
SPAT
Enema
4.1
6.8
18
44
SFA20
NOMESCO Finland
Two-surface restoration
1.4
6.8
562
4681
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
2.7
6.8
35
132
SPAT1125
SPAT
Stoma care and guidance
2.9
6.8
30
104
A01
ICPC
Pain general/multiple sites
1.7
6.7
126
776
K02
ICD-10 Finland
Dental caries
2.0
6.7
72
373
S20.2
ICD-10 Finland
Contusion of thorax
2.0
6.7
70
359
Z02.7
ICD-10 Finland
Issue of medical certificate
1.9
6.7
90
503
F06.2
ICD-10 Finland
Organic delusional [schizophrenia-like] disorder
22.6
6.7
9
*
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
2.2
6.7
55
258
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
2.7
6.6
34
128
WX002
NOMESCO Finland
Sedation and analgesia
1.5
6.6
242
1746
AXX01
NOMESCO Finland
Memory assessment
4.2
6.6
17
41
OAB73, ,
SPAT
8.7
6.6
13
15
F06.0
ICD-10 Finland
Organic hallucinosis
8.7
6.6
13
15
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
6.5
711
6170
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.5
433
3474
WX290
NOMESCO Finland
Other blockage of nerve
1.4
6.5
407
3233
G04CA52
ATC
tamsulosin and dutasteride; systemic
1.5
6.5
189
1297
NAG66
NOMESCO Finland
Posterior interbody fusion of lumbar spine, 2 vertebrae
6.2
6.5
16
26
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.2
6.5
6
302
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.4
483
3950
S32.5
ICD-10 Finland
Fracture of pubis
4.1
6.4
17
42
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.8
6.3
89
505
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
6.0
6.3
16
27
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.5
6.3
233
1681
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
0.3
6.3
12
465
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
2.3
6.3
44
193
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
6.2
157
1042
U05
ICPC
Urination problems other
1.8
6.2
84
470
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
6.2
158
1054
G81.9
ICD-10 Finland
Hemiplegia, unspecified
3.8
6.1
18
48
ZYC01
NOMESCO Finland
Remote contact by phone
1.9
6.1
69
365
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
2.6
6.1
33
128
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
0.3
6.0
12
455
SPAT1279
SPAT
Preparation of immediate hospitalisation
3.2
6.0
23
73
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
2.7
6.0
31
117
C08CA01
ATC
amlodipine; oral
0.7
6.0
356
4422

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
67
37
19.11
84.25
2.4
1.3
117.62
136.23
nmol/l
0.20
34
26
610
3718
2.30
43.30
5.1
3.6
—
—
—
0
0
904
7249
1.99
23.14
7.8
5.2
7141.04
1775.34
e6/l
0.77
23
126
376
2367
1.86
20.29
1.9
1.8
1217.65
1171.94
nmol/l
0.41
299
1772
264
4215
0.52
19.09
2.8
3.5
7.23
7.40
mmol/l
0.31
221
3503
263
4189
0.52
18.78
2.8
3.6
40.19
49.59
mg/l
0.66
186
2793
531
3766
1.73
18.75
2.7
2.3
237.92
235.19
u/l
0.03
515
3553
777
9157
0.57
17.66
3.7
4.7
1.09
1.28
mmol/l
17.04
700
8197
728
5716
1.69
16.95
5.7
4.3
8.38
2.74
estimate
0.29
178
1278
718
5632
1.68
16.64
5.7
4.3
0.00
0.00
estimate
-0.00
170
1248
520
3757
1.68
16.51
2.0
1.8
18.98
20.00
nmol/l
0.86
467
3141
726
5748
1.66
15.89
5.8
4.3
0.00
0.26
estimate
0.52
168
1191
835
9585
0.58
15.70
4.2
5.6
4.24
4.38
mmol/l
3.95
763
8749
549
4060
1.65
15.67
4.3
3.7
36.01
99.28
e6/l
2.35
434
3206
288
4295
0.57
15.40
3.6
4.3
6.04
9.14
mg/mmol
1.58
197
2761
830
9520
0.59
15.09
4.2
5.5
1.38
1.42
mmol/l
1.93
756
8612
584
4420
1.62
14.95
4.9
4.3
121.92
127.25
e6/l
0.06
444
3291
594
4515
1.62
14.94
4.7
3.8
6.23
6.26
ph
0.28
322
2473
483
3495
1.64
14.79
4.2
3.6
0.50
0.49
e6/l
0.02
375
2665
286
4215
0.58
14.30
1.5
2.0
1.16
1.30
mmol/l
3.49
236
3422
678
5432
1.57
12.85
2.5
2.3
83.45
93.85
pmol/l
10.25
475
2938
547
4193
1.56
12.49
6.0
4.4
0.06
0.05
estimate
0.01
145
1046
877
9796
0.62
11.80
4.8
6.5
2.44
2.50
mmol/l
1.20
800
8892
369
2621
1.59
11.56
1.9
1.8
374.95
17225537.64
pmol/l
1.44
318
2119
811
6880
1.55
11.01
4.9
5.5
6.43
6.87
mmol/l
13.45
795
6601
740
6158
1.52
10.97
5.3
7.8
1.21
1.21
mmol/l
0.03
642
5283
497
3821
1.51
10.68
4.2
4.7
—
—
—
0
0
437
3287
1.52
10.34
5.6
4.3
0.00
0.00
estimate
0.78
139
1114
390
2871
1.53
10.17
3.1
2.8
4.70
4.21
e6/l
0.47
359
2641
313
2223
1.55
9.51
3.8
3.3
1.56
1.06
e6/l
0.84
174
1268
339
2470
1.52
9.10
3.8
3.2
598.35
540.61
mosm/kgh2o
5.67
313
2180
861
9512
0.67
8.60
6.6
7.5
39.17
40.50
mmol/mol
4.86
789
8743
383
2893
1.47
8.52
5.5
3.9
0.04
0.05
estimate
0.04
140
967
24
62
3.93
8.44
1.1
1.1
114.92
137.04
nmol/l
2.42
24
62
315
4159
0.67
8.25
2.3
2.3
—
—
—
0
0
580
4755
1.42
8.23
5.4
4.5
37.23
85.70
ng/l
1.81
501
3840
476
3766
1.44
8.23
2.4
2.7
—
—
—
0
0
620
5185
1.40
7.64
2.8
3.0
—
—
estimate
—
0
0
334
2510
1.46
7.46
5.6
4.5
1.02
1.02
kg/l
3.26
227
1727
654
5545
1.39
7.29
5.3
7.0
1.20
1.21
mmol/l
1.48
606
5103
349
2669
1.43
7.03
4.8
4.0
0.60
0.13
—
5
39
463
3721
1.40
7.03
3.0
4.5
7.40
7.40
ph
3.31
328
2714
282
2074
1.47
6.98
4.1
3.4
2.30
1.65
e6/l
0.63
139
1112
374
2924
1.40
6.58
3.8
4.5
84.84
83.72
%
0.42
369
2870
693
6029
1.35
6.06
13.9
19.4
1.23
1.35
inr
8.76
604
5072
132
848
1.63
6.01
4.0
3.0
6.08
6.03
ph
0.30
100
616
136
884
1.61
5.91
5.6
6.5
25.77
24.34
mmol/l
6.00
130
845
356
2814
1.38
5.73
4.5
3.4
0.18
0.03
1.00
22
92
50
964
0.50
5.67
1.4
1.5
—
—
—
0
0
78
1311
0.57
5.61
1.2
1.3
464.62
483.25
titre
0.03
13
308
899
9667
0.72
5.33
4.8
5.9
6.01
6.12
mmol/l
2.03
798
8678
224
1658
1.43
5.24
4.2
7.6
7.42
7.41
ph
0.83
130
946
222
1651
1.42
5.05
4.2
7.5
1.69
0.89
mmol/l
3.07
192
1342
405
3323
1.33
4.98
2.5
2.4
3.21
2.96
mg/l
0.99
351
2843
46
873
0.51
4.98
4.8
2.9
9.53
10.97
g/l
2.28
40
796
242
3112
0.72
4.84
1.9
3.1
310.70
361.76
umol/l
10.06
189
2665
34
697
0.47
4.63
1.6
1.9
0.99
1.54
g/l
2.42
28
631
220
1659
1.40
4.61
4.2
7.6
5.24
5.08
kpa
1.97
211
1596
220
1660
1.40
4.59
4.2
7.5
12.51
11.83
kpa
0.97
210
1601
241
3075
0.73
4.54
3.7
3.7
—
—
—
0
0
112
741
1.56
4.54
2.6
2.6
0.65
0.62
%
0.51
112
736
624
5476
1.29
4.53
4.0
5.3
35.06
34.71
g/l
0.86
580
5110
67
392
1.75
4.37
3.2
3.9
3.88
3.98
mmol/l
1.15
67
387
49
868
0.55
4.26
1.5
1.6
—
—
—
0
0
98
641
1.58
4.18
5.9
4.0
1.02
1.02
ratio
1.73
88
589
61
352
1.77
4.18
4.5
3.5
1.49
1.61
mmol/l
0.63
61
344
97
1436
0.65
4.12
3.2
4.3
3.41
22.62
ug/l
2.63
79
1206
110
1571
0.67
3.91
1.2
1.3
8.92
14.95
u/ml
0.51
40
521
28
577
0.47
3.90
1.6
1.4
—
—
—
0
0
185
1395
1.39
3.86
1.9
1.8
—
—
—
0
0
53
301
1.80
3.85
4.8
3.7
7.26
7.59
mmol/l
0.48
53
293
253
2009
1.33
3.78
2.3
2.0
29.39
29.97
s
0.95
247
1946
333
2746
1.29
3.77
1.3
1.3
—
—
—
0
0
21
84
2.53
3.72
4.6
2.8
—
—
—
0
0
96
643
1.54
3.72
4.9
4.7
1.39
1.58
%
1.44
91
607
195
1495
1.36
3.67
4.6
7.8
95.68
95.33
%
0.33
188
1448
53
880
0.58
3.66
1.3
1.6
—
—
—
0
0
67
1039
0.62
3.51
1.2
1.4
—
—
—
0
0
10
303
0.32
3.45
1.7
1.2
—
858.89
—
0
9
15
371
0.40
3.37
1.4
1.3
—
—
—
0
0
14
356
0.39
3.35
1.5
1.6
0.16
0.35
mg/l
—
5
168
53
318
1.70
3.23
8.9
14.0
—
—
—
0
0
124
1670
0.71
3.18
1.2
1.3
28.65
38.35
iu/ml
0.62
20
519
525
4644
1.23
3.14
2.9
3.1
136.46
161.69
ug/l
1.57
470
4235
19
414
0.45
3.13
1.1
1.7
4.75
8.73
iu/ml
—
6
97
179
1388
1.34
3.13
4.6
8.2
123.57
120.43
g/l
1.34
173
1355
96
669
1.47
3.11
3.6
3.4
25.68
25.23
mmol/l
0.88
89
645
74
1092
0.66
3.11
1.4
1.5
—
—
—
0
0
340
2877
1.25
3.04
2.3
2.6
—
—
—
0
0
182
1424
1.33
2.99
3.3
3.7
5.81
5.85
kpa
0.28
177
1384
536
4773
1.22
2.95
2.4
2.4
72.46
78.96
nmol/l
7.15
461
4174
6
196
0.30
2.94
1.0
1.3
—
—
—
0
0
145
1101
1.36
2.91
2.8
2.5
0.47
0.54
e6/l
0.18
134
1061
53
330
1.63
2.85
2.5
3.6
2.52
1.62
index
0.42
21
181
5
174
0.28
2.83
1.6
1.5
5.40
6.45
mmol/l
—
5
166
28
515
0.53
2.83
1.4
1.4
—
13.31
—
0
8
5
167
0.30
2.70
1.0
1.0
—
—
—
0
0
53
335
1.61
2.70
8.1
5.1
—
—
—
0
0
16
349
0.45
2.68
1.4
1.4
—
—
—
0
0
83
585
1.45
2.58
2.5
2.1
—
—
—
0
0
70
1001
0.68
2.54
1.9
2.3
12.60
12.82
nmol/l
0.08
60
880
7
190
0.36
2.42
1.3
1.6
—
—
—
0
0
6
12
5.02
2.40
2.7
2.7
0.83
0.50
u/field
—
6
12
13
291
0.44
2.36
3.1
2.0
10.00
12.79
mg/l
0.90
13
269
9
219
0.41
2.31
1.0
1.2
—
—
—
0
0
172
1386
1.28
2.29
3.3
3.8
2.28
1.98
mmol/l
0.68
155
1177
141
1107
1.31
2.29
2.7
2.2
0.00
0.02
estimate
0.50
23
199
1017
9768
1.26
2.28
23.7
20.3
28.00
27.90
mg/l
0.03
921
8357
11
257
0.42
2.24
1.3
1.6
—
—
—
0
0
18
350
0.51
2.22
2.2
3.5
0.68
0.83
nmol/l
0.57
12
288
0
62
0.00
2.22
0.0
1.1
—
—
—
0
0
128
998
1.32
2.19
3.1
4.1
1.22
1.22
mmol/l
0.04
104
859
118
911
1.33
2.17
4.3
9.6
0.73
0.64
%
1.62
118
904
116
895
1.33
2.14
6.5
4.3
—
—
—
0
0
176
1444
1.26
2.04
3.4
3.8
7.39
7.38
ph
0.79
96
863
989
10235
0.81
2.01
10.0
13.7
14.78
25.35
u/l
130.19
902
9882
21
374
0.55
1.98
1.1
1.2
—
—
—
0
0
26
436
0.59
1.97
1.3
1.2
—
—
—
0
0
106
1353
0.76
1.93
2.1
3.4
5.30
5.06
e9/l
0.08
78
1145
8
189
0.42
1.93
1.0
1.5
—
—
—
0
0
6
158
0.38
1.89
1.0
2.4
—
—
—
0
0
0
54
0.00
1.85
0.0
2.1
—
1112.33
—
0
42
8
181
0.44
1.82
1.0
1.1
—
—
—
0
0
71
951
0.73
1.81
1.5
1.5
—
—
—
0
0
78
1021
0.75
1.72
3.1
4.2
1.21
0.70
%
0.41
19
355
5
13
3.86
1.71
2.6
1.0
—
—
—
0
0
0
47
0.00
1.70
0.0
2.0
—
38868.07
—
0
29
21
119
1.78
1.67
1.6
1.2
—
—
—
0
0
18
97
1.87
1.66
1.2
1.2
289.98
345.33
nmol/l
0.68
12
78
13
62
2.11
1.66
1.3
1.5
—
—
—
0
0
5
133
0.37
1.62
1.4
1.2
—
—
—
0
0
12
237
0.50
1.62
2.1
2.9
53.83
59.92
%
1.13
12
237
278
2444
1.18
1.61
4.2
4.4
56.16
367.42
ng/l
10.00
236
2129
37
247
1.51
1.59
3.1
4.0
21.93
29.80
mg/l
1.06
24
172
117
945
1.26
1.58
4.6
9.3
1.39
1.29
%
0.48
117
938
150
1787
0.82
1.54
3.4
5.8
1.00
1.03
mmol/l
1.10
138
1657
36
526
0.67
1.54
2.6
3.5
20.50
7780.76
u/ml
0.86
31
453
235
2046
1.18
1.52
2.1
2.7
2.28
2.23
g/l
0.65
213
1892
7
27
2.60
1.51
1.1
1.3
—
—
—
0
0
0
44
0.00
1.51
0.0
1.8
—
—
—
0
0
403
3662
1.15
1.51
2.4
2.7
52.10
83.45
u/l
0.81
371
3378
249
2188
1.17
1.45
2.2
2.8
10.65
12.15
umol/l
2.72
227
2037
82
1038
0.77
1.45
3.4
4.6
0.13
0.10
%
0.09
15
305
7
152
0.46
1.44
1.1
1.2
—
—
—
0
0
10
200
0.50
1.42
2.1
2.5
—
—
—
0
0
86
1077
0.78
1.40
3.1
4.3
0.72
0.91
%
0.28
18
376
5
123
0.40
1.37
1.4
1.5
156.80
35.04
ng/l
—
5
123
36
512
0.69
1.36
1.2
1.3
—
—
—
0
0
8
162
0.49
1.36
1.0
1.3
—
—
—
0
0
38
265
1.45
1.35
2.9
5.1
2.23
2.53
mmol/l
0.31
29
185
0
40
0.00
1.32
0.0
1.3
—
28.03
—
0
29
105
1266
0.81
1.24
1.3
1.3
—
—
—
0
0
278
3083
0.87
1.22
3.1
3.6
0.71
0.79
ug/l
0.68
198
2191
195
1707
1.17
1.20
1.9
2.6
1.52
1.82
%
5.17
172
1526
106
1271
0.82
1.19
3.8
7.0
9.84
11.26
mmol/l
1.23
98
1219
40
543
0.73
1.18
1.2
4.0
47.15
62.73
mg/l
0.60
35
467
36
497
0.72
1.18
1.2
3.8
1.89
4.01
ratio
1.06
24
292
12
64
1.88
1.18
3.2
1.6
77.25
91.45
umol/l
1.10
12
64
40
542
0.73
1.17
1.2
4.0
26.21
93.35
mg/l
1.59
34
469
0
34
0.00
1.16
0.0
1.5
—
—
—
0
0
160
1842
0.85
1.16
1.3
1.6
2.29
2.84
g/l
3.42
72
1062
0
35
0.00
1.15
0.0
1.4
—
22.54
—
0
24
83
1016
0.80
1.14
3.1
4.4
0.20
0.11
%
0.24
15
318
7
139
0.50
1.09
1.0
1.3
0.79
0.90
g/l
—
7
139
80
650
1.25
1.09
1.9
1.8
2.59
1.90
ug/l
0.20
63
576
34
462
0.73
1.04
1.1
1.2
92.23
122.54
u/ml
—
7
159
31
221
1.41
1.03
1.7
1.2
—
—
—
0
0
21
310
0.67
1.02
1.9
2.5
145.54
110.39
ug/min
0.22
13
184
285
2601
1.13
0.98
2.5
3.2
2.43
2.46
mmol/l
4.01
251
2339
0
29
0.00
0.97
0.0
3.1
—
—
—
0
0
0
29
0.00
0.97
0.0
2.2
—
8.32
—
0
22
0
30
0.00
0.97
0.0
1.6
—
26.22
—
0
25
0
30
0.00
0.97
0.0
1.5
—
159.14
—
0
7
258
2344
1.13
0.95
1.7
1.7
1.46
1.59
mg/l
0.22
209
1859
777
7488
1.11
0.93
3.9
4.1
15.14
15.11
pmol/l
0.10
703
6713
10
55
1.83
0.92
2.0
1.5
1.30
3.79
u/field
—
10
39
18
118
1.53
0.91
1.9
3.2
17.86
11.32
index
—
7
66
75
620
1.22
0.90
2.4
2.4
—
—
—
0
0
11
182
0.60
0.90
1.0
1.5
—
—
—
0
0
5
102
0.49
0.89
1.0
1.2
0.58
0.69
ratio
—
5
24
67
548
1.24
0.89
2.5
2.2
0.00
1.79
estimate
0.50
12
140
19
276
0.68
0.87
1.2
1.1
—
—
—
0
0
133
1509
0.87
0.83
1.4
1.4
—
—
—
0
0
60
490
1.24
0.82
1.5
1.3
—
—
—
0
0
8
47
1.71
0.80
2.1
2.3
—
—
—
0
0
597
6233
0.92
0.80
2.8
3.5
43.08
58.14
u/l
1.82
552
5744
26
351
0.74
0.80
1.1
1.2
0.20
1.07
u/ml
—
5
30
0
24
0.00
0.79
0.0
3.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.0
—
—
—
0
0
0
26
0.00
0.78
0.0
4.7
—
—
—
0
0
0
26
0.00
0.78
0.0
1.5
—
—
—
0
0
14
90
1.56
0.78
1.6
2.5
16.88
16.12
%
0.39
14
90
18
123
1.47
0.77
2.2
2.1
—
—
—
0
0
7
125
0.56
0.77
1.0
1.2
1.41
1.51
g/l
—
7
125
0
27
0.00
0.77
0.0
1.6
—
4000.00
—
0
6
25
336
0.74
0.76
1.1
1.7
—
—
—
0
0
12
185
0.65
0.75
2.0
3.0
3.65
4.46
e9/l
0.76
12
185
32
245
1.31
0.74
1.7
1.3
1.15
67.68
e6/l
1.23
27
182
232
2130
1.11
0.73
2.0
3.3
0.83
0.82
mmol/l
2.39
219
2015
492
4682
1.09
0.72
13.0
13.0
0.00
0.00
e9/l
1.21
398
3814
41
509
0.80
0.70
2.3
3.2
25.79
24.89
mmol/l
0.95
41
501
15
101
1.49
0.70
1.8
2.3
7.58
7.97
mmol/l
0.23
15
101
36
283
1.28
0.70
1.6
1.3
495.03
619.80
mg/l
1.14
36
265
7
120
0.58
0.67
1.1
1.1
—
—
—
0
0
60
709
0.84
0.65
1.1
1.2
—
—
—
0
0
209
1922
1.11
0.65
2.2
2.8
19.60
22.10
%
1.91
192
1794
434
4125
1.08
0.65
2.6
3.6
2.33
2.35
mmol/l
1.89
394
3697
14
201
0.69
0.64
1.2
1.1
—
—
—
0
0
55
652
0.84
0.62
2.5
4.0
—
—
—
0
0
60
704
0.84
0.61
1.5
1.9
1.73
1.56
g/l
1.08
51
622
148
1342
1.12
0.60
1.7
2.6
59.77
68.59
e9/l
2.52
111
1010
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
3.10
—
0
8
16
114
1.41
0.59
1.8
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
42
506
0.82
0.57
1.8
3.5
4.42
4.40
pmol/l
0.05
37
446
28
220
1.28
0.57
2.0
1.9
1.86
1.66
mmol/l
0.34
28
212
14
195
0.71
0.56
1.5
2.3
—
—
—
0
0
37
302
1.23
0.56
3.0
4.1
—
—
—
0
0
23
294
0.78
0.53
1.2
1.3
—
—
—
0
0
11
158
0.69
0.53
1.4
2.4
1.45
0.28
mmol/l
0.68
11
152
630
6107
1.07
0.52
4.0
7.1
11.05
12.27
umol/l
2.13
588
5830
7
45
1.56
0.49
2.1
1.1
0.56
0.49
ratio
—
7
23
194
1807
1.09
0.48
2.1
2.1
—
—
—
0
0
7
46
1.52
0.48
1.1
1.2
—
71.20
%
—
0
5
852
8353
1.07
0.47
5.7
9.0
79.40
82.06
u/l
0.94
789
7900
565
5477
1.06
0.45
5.0
6.2
0.54
0.62
e9/l
13.83
478
4634
91
1007
0.90
0.44
1.8
2.2
412.23
379.86
nmol/l
0.87
81
920
777
7606
1.06
0.44
29.9
27.1
331.77
331.48
g/l
0.42
771
7564
1033
10447
0.92
0.43
33.9
30.6
6.57
6.94
e9/l
7.41
1011
10167
573
5565
1.06
0.42
5.1
6.3
1.55
1.89
e9/l
6.43
508
4838
6
95
0.63
0.42
1.3
1.2
28.50
35.69
mmol/l
—
6
86
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
17.29
—
0
7
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
1036.72
—
0
5
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
190.71
—
0
7
145
1559
0.92
0.40
1.2
1.3
—
—
—
0
0
800
7848
1.06
0.40
27.7
25.1
13.70
13.92
%
4.69
793
7727
11
149
0.74
0.40
3.1
2.6
—
—
—
0
0
0
18
0.00
0.40
0.0
2.9
—
0.61
—
0
18
35
297
1.18
0.39
1.3
2.6
29.00
33.98
umol/l
1.05
29
258
0
19
0.00
0.39
0.0
1.4
—
49.00
—
0
19
0
19
0.00
0.39
0.0
1.1
—
900.00
—
0
6
1034
10447
0.93
0.38
34.2
30.8
129.35
133.25
g/l
14.33
1021
10304
13
170
0.76
0.38
1.1
1.5
—
—
—
0
0
13
170
0.76
0.38
1.1
1.5
—
—
—
0
0
13
170
0.76
0.38
1.1
1.5
—
—
—
0
0
13
170
0.76
0.38
1.1
1.5
—
—
—
0
0
1034
10446
0.93
0.38
33.9
30.5
240.82
237.27
e9/l
1.04
1016
10205
1034
10446
0.93
0.38
33.8
30.4
30.52
30.51
pg
0.06
1022
10298
1034
10446
0.93
0.38
34.2
31.2
38.45
39.79
%
10.12
1022
10292
1034
10446
0.93
0.38
33.9
30.5
4.27
4.41
e12/l
14.21
1009
10165
10
136
0.73
0.37
3.3
4.7
—
—
—
0
0
627
6120
1.05
0.37
6.8
9.9
4.33
4.30
e9/l
0.09
540
5286
1034
10444
0.93
0.37
33.8
30.5
91.95
91.90
fl
0.14
1022
10298
564
5492
1.05
0.36
5.0
6.2
0.03
0.04
e9/l
8.67
476
4648
11
81
1.36
0.36
1.2
1.1
—
—
—
0
0
11
81
1.36
0.36
1.2
1.2
97.64
100.23
pmol/l
0.11
11
81
15
190
0.79
0.35
2.3
1.7
—
—
—
0
0
6
45
1.33
0.33
1.3
1.4
133.17
176.55
mmol/24h
—
6
45
124
1325
0.93
0.32
2.2
2.8
7.51
8.80
umol/l
0.35
109
1193
317
3285
0.95
0.30
4.9
6.7
—
—
—
0
0
38
334
1.14
0.30
1.7
1.6
13216.84
14856.26
e6/l
0.11
31
238
33
287
1.15
0.30
2.6
2.8
15.82
15.90
%
0.06
33
279
56
619
0.90
0.30
2.4
2.9
—
—
—
0
0
8
108
0.74
0.29
1.0
1.1
—
—
—
0
0
129
1367
0.94
0.27
1.5
1.5
—
—
—
0
0
9
121
0.74
0.27
1.4
2.7
405.56
987.30
mg
—
9
121
116
1232
0.94
0.26
1.3
3.0
64.96
66.27
g/l
1.05
101
1137
210
2013
1.05
0.26
1.2
1.2
1.14
1.42
u/ml
0.23
52
510
54
492
1.10
0.25
2.4
4.1
25.38
24.99
mmol/l
0.48
46
453
575
5639
1.04
0.25
5.1
6.4
0.16
0.20
e9/l
6.96
505
4858
519
5086
1.04
0.23
5.3
6.5
0.60
0.66
%
1.78
482
4765
998
9901
1.05
0.22
21.4
18.3
—
—
—
0
0
20
231
0.86
0.22
1.4
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
5.0
—
0.22
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
25.66
—
0
12
919
9107
1.04
0.21
5.1
5.3
2.03
2.04
mu/l
0.17
838
8211
0
13
0.00
0.21
0.0
1.2
—
2.05
—
0
13
0
13
0.00
0.21
0.0
1.1
—
0.02
—
0
13
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
64.56
—
0
9
0
14
0.00
0.20
0.0
1.0
—
5.16
—
0
6
0
14
0.00
0.20
0.0
1.1
—
240.04
—
0
9
338
3462
0.97
0.19
2.8
3.3
32.97
35.05
u/l
0.17
320
3258
515
5061
1.03
0.19
5.0
6.4
61.92
58.74
%
8.80
490
4824
518
5091
1.03
0.19
5.3
6.5
8.45
9.23
%
9.51
485
4767
33
364
0.90
0.19
2.3
2.7
63.37
58.70
%
0.63
33
351
516
5248
0.97
0.19
4.8
6.1
3.32
3.18
ug/l
0.08
461
4694
31
281
1.11
0.17
1.2
1.2
—
—
—
0
0
7
62
1.13
0.17
2.1
1.1
338.00
307.19
mg/l
—
7
54
33
361
0.91
0.17
1.2
1.5
279.08
268.87
ug/g
0.10
28
226
12
101
1.19
0.16
1.2
1.3
—
—
—
0
0
516
5082
1.03
0.16
5.2
6.5
2.59
2.83
%
1.84
482
4757
125
1201
1.05
0.16
4.2
8.9
—
—
—
0
0
6
78
0.77
0.15
1.0
1.1
—
—
—
0
0
114
1095
1.05
0.15
2.4
2.5
30.94
40.44
u/l
1.14
96
913
523
5157
1.02
0.15
5.2
6.5
23.58
25.62
%
4.72
494
4880
26
286
0.91
0.15
1.0
1.1
—
—
—
0
0
1035
10401
0.97
0.14
28.7
27.3
71.47
85.75
umol/l
49.58
1022
10264
7
87
0.80
0.14
2.4
2.3
—
—
—
0
0
26
237
1.10
0.14
1.5
2.2
0.69
0.89
%
1.71
17
177
10
84
1.19
0.14
2.9
2.5
—
—
—
0
0
8
98
0.82
0.13
1.3
1.4
—
—
—
0
0
1033
10281
1.03
0.13
27.8
24.8
140.03
139.62
mmol/l
6.78
1020
10081
9
106
0.85
0.13
1.0
1.2
—
—
—
0
0
391
3854
1.02
0.12
4.9
6.2
—
—
—
0
0
111
1147
0.96
0.11
2.8
3.1
232.83
229.12
ng/l
0.03
101
1058
95
982
0.96
0.10
2.5
4.0
81.16
99.66
ng/l
2.04
72
841
89
921
0.96
0.10
2.6
3.9
7.43
7.42
ph
2.67
73
779
5
46
1.09
0.09
3.0
3.5
27.60
31.95
umol/l
—
5
32
211
2149
0.98
0.09
4.1
4.9
—
—
—
0
0
1033
10294
1.02
0.09
27.8
25.0
3.96
4.01
mmol/l
10.01
1018
10083
5
64
0.78
0.08
1.4
1.2
9.98
9.96
mmol/l
—
5
58
7
64
1.09
0.08
2.1
1.1
68.57
48.98
mg/l
—
7
54
117
1197
0.98
0.07
2.7
2.6
6.95
6.88
ug/l
0.02
91
1064
12
108
1.11
0.07
1.1
1.2
—
—
—
0
0
7
82
0.85
0.07
1.3
1.1
—
—
—
0
0
7
82
0.85
0.07
1.3
1.1
—
—
—
0
0
21
196
1.07
0.07
1.4
1.8
—
—
—
0
0
7
84
0.83
0.07
1.0
1.1
—
—
—
0
0
16
173
0.92
0.06
1.1
1.1
—
—
—
0
0
9
100
0.90
0.06
1.2
1.2
—
—
—
0
0
432
4353
0.99
0.06
2.8
3.4
1106.70
1696.41
ng/l
5.21
375
3822
23
217
1.06
0.06
1.1
1.3
0.70
0.86
nmol/l
0.83
17
177
66
643
1.03
0.05
1.2
1.3
—
—
—
0
0
110
1080
1.02
0.05
2.0
2.3
205.26
152.72
ug/g
1.09
96
865
12
130
0.92
0.04
1.3
1.1
—
—
—
0
0
30
311
0.96
0.03
1.5
1.6
20.22
24.97
u/ml
—
5
53
122
1206
1.01
0.03
3.4
4.6
7.39
7.35
ph
3.06
93
876
45
460
0.98
0.02
2.1
2.9
210.68
407.21
mg/l
0.78
19
190
93
941
0.99
0.02
2.5
3.9
5.15
5.15
kpa
0.00
83
903
80
791
1.01
0.01
2.9
3.8
24.93
24.16
mmol/l
1.96
80
780
62
628
0.99
0.01
2.3
2.7
17.00
20.92
au/ml
—
5
44
122
1212
1.01
0.01
2.0
2.3
0.20
0.20
g/l
0.18
109
1118
13
124
1.05
0.00
1.5
1.3
—
—
nmol/l
—
0
0
33
328
1.01
0.00
2.2
2.4
125.71
128.14
g/l
0.22
28
259
103
1029
1.00
0.00
1.3
2.8
—
—
—
0
0
53
533
0.99
0.00
1.1
2.8
8.96
10.78
g/l
4.76
45
477
5
54
0.93
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
381.17
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
2.0
1.8
—
—
—
0
0
5
54
0.93
-0.00
1.2
3.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.3
—
12.14
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
0.05
—
0
7
0
7
0.00
-0.00
0.0
5.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
4.74
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
94.67
—
0
6
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
30.86
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: PDMED_LEVODOPA_DECARBOX_COMTINHIBITOR – Use of levodopa decarbox-comt-inhibitor

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).