Dementia due to Parkinsons disease, excluding more controls

PD_DEMENTIA_EXMORE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
G6_PARKINSON, F5_PSYCH, NEURODIS

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9967 4278 5570
Only index persons 8196 3544 4652
Unadjusted period prevalence (%)
Whole population 0.14 0.12 0.16
Only index persons 0.16 0.13 0.18
Median age at first event (years)
Whole population 77.63 78.85 76.70
Only index persons 77.59 78.87 76.63

-FinnGen-

Key figures

All Female Male
Number of individuals 965 348 617
Unadjusted period prevalence (%) 0.23 0.12 0.28
Median age at first event (years) 76.80 77.86 76.21

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
992
Matched controls
9920
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N05AH04
ATC
quetiapine; oral
76.8
307.7
501
130
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
17290.1
307.7
953
14
N04BD01
ATC
selegiline; oral
7607.1
307.7
449
*
N04BC05
ATC
pramipexole; oral
39.2
307.7
444
201
N87
ICPC
Parkinsonism
5325.2
307.7
480
*
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
+∞
307.7
417
*
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
+∞
307.7
915
*
G20
ICD-10 Finland
Parkinson disease
4503599627370496.0
307.7
954
*
N06DA03
ATC
rivastigmine; oral, transdermal
2671.1
307.7
572
5
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
+∞
307.7
824
*
AA1AD
NOMESCO Finland
CT of head and brain
9.7
288.5
503
948
N06DA02
ATC
donepezil; oral
149.3
283.0
141
11
N06DX01
ATC
memantine; oral
125.2
276.4
140
13
N04BD02
ATC
rasagiline; oral
3129.0
272.8
251
*
N04BC04
ATC
ropinirole; oral
3129.0
272.8
251
*
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
246.4
226
*
N03AE01
ATC
clonazepam; systemic
27.3
235.9
167
73
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
113.6
234.5
120
12
S06.0
ICD-10 Finland
Concussion
37.8
226.8
143
44
R25.1
ICD-10 Finland
Tremor, unspecified
35.4
222.3
143
47
193
Kela drug reimbursment
Rasagiline
+∞
221.4
204
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
100.9
208.1
108
12
R53
ICD-10 Finland
Malaise and fatigue
7.2
204.5
441
993
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
6.9
195.4
436
1009
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
49.3
174.3
102
23
I95.1
ICD-10 Finland
Orthostatic hypotension
13.4
172.3
175
156
N05AX08
ATC
risperidone; systemic
23.7
171.8
127
61
N04BX02
ATC
entacapone; oral
+∞
169.8
158
*
XA800
NOMESCO Finland
Neuropsychological investigation
77.0
169.1
91
13
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
5.7
164.3
533
1685
H02AA02
ATC
fludrocortisone; oral
57.4
157.2
89
17
N04BB01
ATC
amantadine; oral
31.5
146.8
97
34
F02.39
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
+∞
140.0
131
*
N06AX11
ATC
mirtazapine; oral
5.4
139.2
380
1016
A28
ICPC
Limited function/disability NOS
5.3
137.2
397
1113
N06AB10
ATC
escitalopram; oral
8.7
136.0
193
269
F32.9
ICD-10 Finland
Depressive episode, unspecified
37.1
135.4
85
25
G47.3
ICD-10 Finland
Sleep apnoea
16.5
131.8
115
78
G04BD12
ATC
mirabegron; oral
5.9
127.9
290
654
L28
ICPC
Limited function/disability (L)
4.8
115.6
354
1021
SPAT1229
SPAT
Assessment of need for aid
8.0
113.2
170
251
S01.0
ICD-10 Finland
Open wound of scalp
7.6
112.9
179
281
A06AD11
ATC
lactulose; oral
4.9
112.6
330
917
N05BA04
ATC
oxazepam; oral
4.9
111.6
326
903
P20
ICPC
Memory disturbance
5.7
110.7
248
548
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
8.9
110.4
148
191
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
12.0
108.9
115
107
SPAT1216
SPAT
Assessment of functional ability
4.8
100.9
286
767
R41.0
ICD-10 Finland
Disorientation, unspecified
17.8
98.7
82
50
R4130
NOMESCO Finland
Speech therapy
23.5
95.7
70
32
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
999.1
94.5
91
*
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
55.9
93.2
53
10
N29
ICPC
Neurological sympt/complt other
33.5
93.1
60
19
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
7.2
91.3
148
236
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.6
89.5
260
705
N04BC09
ATC
rotigotine; transdermal
926.9
88.1
85
*
R1250
NOMESCO Finland
Evaluation of functional capability
21.1
87.7
67
34
N06AB04
ATC
citalopram; systemic
5.2
86.6
208
482
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
6.6
86.4
153
267
N28
ICPC
Limited function/disability (N)
34.2
85.9
55
17
Z2445
NOMESCO Finland
Psychologist
45.8
80.9
48
11
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
15.5
80.0
71
49
SPAT1234
SPAT
Support of social functional capacity
7.4
78.9
122
184
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
4.2
76.7
256
764
D21
ICPC
Swallowing problem
22.3
76.6
57
27
F02.30
ICD-10 Finland
Dementia in Parkinson's disease without additional symptoms
+∞
73.9
70
*
N05AH03
ATC
olanzapine; systemic
26.8
73.6
51
20
F03
ICD-10 Finland
Unspecified dementia
15.4
73.0
65
45
SPAT1215
SPAT
Assessment of need for medical rehabilitation
9.8
73.0
88
98
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.4
72.2
377
1509
WYA20
NOMESCO Finland
Home visit
20.7
71.7
55
28
S72.0
ICD-10 Finland
Fracture of neck of femur
6.5
71.4
126
218
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
15.1
71.3
64
45
N04AA02
ATC
biperiden; systemic
738.9
71.0
69
*
SPAT1231
SPAT
Assessment of adjustments needed in living environment
13.7
70.6
67
52
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
5.1
69.9
164
369
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.9
68.7
250
788
G30.1
ICD-10 Finland
Alzheimer disease with late onset
24.5
68.4
49
21
W19
ICD-10 Finland
Unspecified fall
5.2
68.3
155
339
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.2
68.1
448
2043
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.9
67.3
248
787
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
6.3
66.6
121
215
U04
ICPC
Incontinence urine
5.7
66.5
134
263
XF606
NOMESCO Finland
Ortostatic test
27.7
65.7
45
17
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
11.0
65.7
72
70
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.8
63.5
238
762
N06AX16
ATC
venlafaxine; oral
7.1
61.4
97
149
F51.0
ICD-10 Finland
Nonorganic insomnia
+∞
60.0
57
*
C07AA05
ATC
propranolol; systemic
4.0
59.1
194
564
F0232, G20,
ICD-10 Finland
+∞
58.9
56
*
A04
ICPC
Weakness/tiredness general
3.7
57.7
215
682
F0230, G20,
ICD-10 Finland
+∞
56.8
54
*
N04BX04
ATC
opicapone; oral
+∞
56.8
54
*
F05.9
ICD-10 Finland
Delirium, unspecified
156.6
56.5
59
*
N39.4
ICD-10 Finland
Other specified urinary incontinence
4.7
56.3
145
350
SPAT1053
SPAT
Memory test
3.4
56.2
252
900
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
+∞
55.8
53
*
F02.32
ICD-10 Finland
Dementia in Parkinson's disease other additional symptoms, mainly hallucinations
+∞
54.7
52
*
SPAT1245
SPAT
Provision of support and information to patient’s family members
6.6
54.2
92
152
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
+∞
52.6
50
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
7.4
51.5
77
111
N19
ICPC
Speech disorder
98.9
51.4
56
6
N05BA06
ATC
lorazepam; systemic, sublingual
6.9
49.7
80
125
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
6.6
49.6
83
135
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
6.6
49.2
83
136
N06AX21
ATC
duloxetine; oral
5.9
48.8
93
172
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
10.9
48.5
53
51
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
9.0
48.1
61
72
R5110, ,
SPAT
4.1
47.2
144
394
N04BC06
ATC
cabergoline; oral
126.0
45.2
48
*
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
457.4
44.6
44
*
N30.0
ICD-10 Finland
Acute cystitis
3.3
44.4
200
708
AAG20
NOMESCO Finland
Stereotactic intracranial implantation of electrodes
+∞
44.1
42
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
44.1
42
*
SPAT1254
SPAT
Administration of medicine
3.2
43.8
202
725
R55
ICD-10 Finland
Syncope and collapse
3.5
43.5
173
566
N06AX26
ATC
vortioxetine; oral
10.7
42.5
47
46
N03AX12
ATC
[U] gabapentin; oral
3.6
41.7
156
490
N03AG01
ATC
valproic acid; systemic, rectal
70.3
41.4
47
7
G25.0
ICD-10 Finland
Essential tremor
10.7
40.7
45
44
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
5.5
39.8
80
155
R1260
NOMESCO Finland
Evaluation of communicative skills
12.6
39.5
39
32
S70.0
ICD-10 Finland
Contusion of hip
5.5
39.1
79
154
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
+∞
38.8
37
*
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
+∞
37.7
36
*
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
+∞
37.7
36
*
R35
ICD-10 Finland
Polyuria
3.9
37.6
122
347
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
13.9
37.5
35
26
P03
ICPC
Feeling depressed
9.2
37.4
46
52
SPAT1172
SPAT
Guidance concerning hydration
6.6
37.1
61
97
NA1AD
NOMESCO Finland
Cervical spine CT examination
6.3
36.8
64
108
N04BC02
ATC
pergolide; oral
+∞
36.7
35
*
S01.1
ICD-10 Finland
Open wound of eyelid and periocular area
7.7
36.3
52
71
N02AA05
ATC
oxycodone; systemic
2.6
36.2
287
1363
R41.3
ICD-10 Finland
Other amnesia
9.5
35.9
43
47
G02CB01
ATC
bromocriptine; systemic
61.0
35.4
41
7
G40.9
ICD-10 Finland
Epilepsy, unspecified
186.6
35.0
36
*
M48.0
ICD-10 Finland
Spinal stenosis
3.1
34.7
165
598
JDB10
NOMESCO Finland
Percutaneous gastrostomy
12.1
34.4
35
30
L89
ICD-10 Finland
Decubitus ulcer and pressure area
8.6
34.1
44
53
XKD06
NOMESCO Finland
Physiologic investigation of micturition
6.4
33.8
57
93
E86
ICD-10 Finland
Volume depletion
6.5
33.4
56
91
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
5.3
33.3
70
141
K59.0
ICD-10 Finland
Constipation
4.2
32.5
91
232
F02.34
ICD-10 Finland
Dementia in Parkinson's disease, other additional symptoms of mixed type
+∞
32.5
31
*
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
327.1
32.0
32
*
P29
ICPC
Psychological sympt/compl other
11.7
31.9
33
29
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
322.6
31.0
31
*
SPAT1305
SPAT
Counselling and guidance related to physical exercise
3.3
30.0
122
401
R44.1
ICD-10 Finland
Visual hallucinations
85.3
29.9
33
*
N03AX16
ATC
[U] pregabalin
2.6
29.8
200
867
I95.9
ICD-10 Finland
Hypotension, unspecified
8.7
29.8
38
45
K90
ICPC
Stroke/cerebrovascular accident
41.5
29.1
36
9
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
10.6
29.0
32
31
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
7.3
29.0
43
61
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
300.4
28.9
29
*
Z75.5
ICD-10 Finland
Holiday relief care
45.2
28.8
35
8
N99
ICPC
Neurological disease other
45.2
28.8
35
8
N06AX03
ATC
mianserin; oral
7.0
28.6
44
65
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.3
28.4
118
393
SPAT1167
SPAT
Insertion of urinary catheter
4.5
28.1
72
171
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
3.0
27.9
134
486
G30.8
ICD-10 Finland
Other Alzheimer disease
103.1
27.8
30
*
G04BD11
ATC
fesoterodine; oral
5.2
27.3
58
118
R42
ICD-10 Finland
Dizziness and giddiness
2.4
27.2
238
1164
SPAT1301
SPAT
No procedures
2.2
27.1
338
1912
K59.09
ICD-10 Finland
Constipation, unspecified
3.3
27.1
108
350
G72.8
ICD-10 Finland
Other specified myopathies
143.9
26.8
28
*
G04BD09
ATC
trospium; oral
6.1
26.7
47
80
N02BE01
ATC
paracetamol; systemic, rectal
2.6
26.4
849
6863
NF1AA
NOMESCO Finland
Hip X-ray examination
2.9
26.3
134
502
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
+∞
26.2
25
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
+∞
26.2
25
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
6.5
25.9
43
69
A06AC01
ATC
ispaghula (psylla seeds); oral
2.2
25.7
273
1445
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
25.6
188
847
R13
ICD-10 Finland
Dysphagia
3.7
25.3
86
251
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.2
25.1
107
361
R32
ICD-10 Finland
Unspecified urinary incontinence
5.8
25.1
47
85
AA5EN
NOMESCO Finland
Brain reseptor or transprot protein distribution isotope imaging
+∞
25.1
24
*
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
71.8
24.9
28
*
N30.9
ICD-10 Finland
Cystitis, unspecified
3.6
24.9
85
249
R56.8
ICD-10 Finland
Other and unspecified convulsions
7.7
24.7
35
47
P70
ICPC
Dementia
20.7
24.5
36
18
N06AB06
ATC
sertraline; oral
4.8
24.1
55
119
F05.1
ICD-10 Finland
Delirium superimposed on dementia
+∞
24.1
23
*
SPAT1297
SPAT
Other function in accordance with speech therapy nomenclature
+∞
24.1
23
*
TAB00
NOMESCO Finland
Lumbar puncture
9.3
23.9
29
32
R47.1
ICD-10 Finland
Dysarthria and anarthria
69.2
23.9
27
*
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
8.8
23.7
30
35
N05CF01
ATC
zopiclone; oral
2.1
23.7
311
1778
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
6.4
23.3
39
63
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.6
23.2
145
603
F02.3
ICD-10 Finland
Dementia in Parkinson disease
+∞
23.0
22
*
N05AH02
ATC
clozapine; systemic
+∞
23.0
22
*
R23
ICPC
Voice symptom/complaint
7.5
22.1
32
44
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
8.7
22.0
28
33
F02.31
ICD-10 Finland
Dementia in Parkinson's disease other additional symptoms, mainly paranoidism
+∞
22.0
21
*
G23.9
ICD-10 Finland
Degenerative disease of basal ganglia, unspecified
+∞
22.0
21
*
SPAT1240
SPAT
Therapeutic discussion
5.4
21.9
44
85
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
18.9
21.8
33
18
J01EA01
ATC
trimethoprim; systemic
2.1
21.8
262
1444
F05.8
ICD-10 Finland
Other delirium
82.0
21.8
24
*
F22.0
ICD-10 Finland
Delusional disorder
224.8
21.7
22
*
J01CA08
ATC
pivmecillinam; oral
2.0
21.5
316
1873
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
5.4
21.4
43
83
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.5
21.3
76
229
Z02.4
ICD-10 Finland
Examination for driving licence
0.4
21.0
157
3011
N05BA01
ATC
diazepam; systemic, rectal
2.8
21.0
117
458
F0234, G20,
ICD-10 Finland
+∞
20.9
20
*
Y94.0
ICD-10 Finland
Accident at home
7.0
20.9
32
47
S01.9
ICD-10 Finland
Open wound of head, part unspecified
7.5
20.9
30
41
N06DA04
ATC
galantamine; oral
78.5
20.8
23
*
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.1
20.7
89
301
UKC02
NOMESCO Finland
Cystoscopy
2.1
20.4
237
1286
X59
ICD-10 Finland
Exposure to unspecified factor
2.4
20.1
157
722
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.5
20.1
146
650
3320A
ICD-9 Finland
Parkinson's disease, Paralysis agitans
+∞
19.9
19
*
N05CD07
ATC
temazepam; oral
2.5
19.7
135
585
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
19.6
427
2863
XKD00
NOMESCO Finland
Uroflowmetry
2.0
19.5
255
1442
G04BD08
ATC
solifenacin; oral
3.1
19.2
86
298
G23.1
ICD-10 Finland
Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
+∞
18.8
18
*
SPAT1262
SPAT
Handing over of treatment supplies
2.2
18.7
193
996
S00.0
ICD-10 Finland
Superficial injury of scalp
6.0
18.5
33
57
Z3226
NOMESCO Finland
Physiotherapist
2.2
18.2
179
906
P01
ICPC
Feeling anxious/nervous/tense
5.6
18.0
34
62
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.3
17.9
148
697
F06.7
ICD-10 Finland
Mild cognitive disorder
7.1
17.9
27
39
SPAT1360
SPAT
Extensive global examination
3.0
17.9
85
305
A29
ICPC
General symptom/complaint other
2.3
17.8
153
732
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
+∞
17.8
17
*
130
Kela drug reimbursment
Malignant tumour
0.1
17.7
16
1010
SPAT1125
SPAT
Stoma care and guidance
5.4
17.6
35
67
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.2
17.3
162
803
S72.1
ICD-10 Finland
Pertrochanteric fracture
4.3
17.1
45
109
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.2
17.1
160
792
R1250, ,
SPAT
5.1
17.0
36
73
M54.5
ICD-10 Finland
Low back pain
1.9
16.9
262
1561
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
16.9
270
1625
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
16.7
16
*
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
+∞
16.7
16
*
R06.5
ICD-10 Finland
Mouth breathing
4.1
16.7
47
120
SPAT1050
SPAT
Extensive neurological examination
6.8
16.6
26
39
AXX01
NOMESCO Finland
Memory assessment
28.1
16.5
22
8
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
172.8
16.5
17
*
G44.2
ICD-10 Finland
Tension-type headache
3.5
16.4
57
169
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
15.7
16.2
26
17
R33
ICD-10 Finland
Retention of urine
2.3
16.1
128
592
ICB01, ,
SPAT
48.3
16.1
19
*
S22.3
ICD-10 Finland
Fracture of rib
2.9
16.0
80
295
SPAT1263
SPAT
Sampling
1.8
15.9
366
2456
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.6
15.9
96
390
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.9
15.8
76
274
N06AA12
ATC
doxepin; systemic
3.7
15.8
50
139
R60.0
ICD-10 Finland
Localized oedema
2.2
15.7
146
720
85000
ICD-8 Finland
Concussion, Current or unspecified
+∞
15.7
15
*
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
+∞
15.7
15
*
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
+∞
15.7
15
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
15.5
206
1161
K91
ICPC
Cerebrovascular disease
38.7
15.4
19
5
S20.2
ICD-10 Finland
Contusion of thorax
3.5
15.4
54
161
J01DB01
ATC
cefalexin; oral
1.8
15.3
705
5726
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
6.2
15.2
26
43
D12
ICPC
Constipation
3.4
15.1
56
173
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
14.9
93
384
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
6.0
14.8
26
44
WX212
NOMESCO Finland
Femoral plexus blockade
4.2
14.8
40
99
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
18.7
14.7
22
12
N03AF02
ATC
oxcarbazepine; oral
21.4
14.7
21
10
S62.3
ICD-10 Finland
Fracture of other metacarpal bone
5.2
14.6
30
59
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
+∞
14.6
14
*
N86
ICPC
Multiple sclerosis
+∞
14.6
14
*
G04CB01
ATC
finasteride; oral
2.0
14.5
193
1086
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
152.2
14.5
15
*
G04CA02
ATC
tamsulosin; oral
1.7
14.5
351
2377
T36
ICD-10 Finland
Poisoning by systemic antibiotics
17.3
14.3
22
13
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
22.6
14.3
20
9
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
4.3
14.2
37
89
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.3
14.0
53
166
Z50.5
ICD-10 Finland
Speech therapy
17.8
13.9
21
12
N06AA09
ATC
amitriptyline; systemic
2.9
13.8
66
237
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
+∞
13.6
13
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
+∞
13.6
13
*
G35
ICD-10 Finland
Multiple sclerosis
+∞
13.6
13
*
30041
ICD-8 Finland
Neuroses, Depressiva
+∞
13.6
13
*
F06.0
ICD-10 Finland
Organic hallucinosis
+∞
13.6
13
*
F023, G20,
ICD-10 Finland
+∞
13.6
13
*
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
141.9
13.5
14
*
N06AX12
ATC
bupropion; oral
13.1
13.4
23
18
ZXD35
NOMESCO Finland
Usual procedure
3.9
13.4
39
102
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.5
13.4
33
76
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
13.4
129
644
A01
ICPC
Pain general/multiple sites
2.5
13.4
89
379
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
21.5
13.4
19
9
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
12.4
13.1
23
19
N06AB03
ATC
fluoxetine; oral
2.8
13.1
66
244
B01AC07
ATC
dipyridamole; systemic
2.9
13.0
61
217
F01.9
ICD-10 Finland
Vascular dementia, unspecified
28.8
13.0
17
6
SPAT1304
SPAT
Counselling and guidance related to ageing
2.3
13.0
105
488
N05BA12
ATC
alprazolam; oral
2.7
12.9
70
269
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
3.7
12.9
40
110
R4110, ,
SPAT
2.2
12.6
116
568
R4120
NOMESCO Finland
Occupational therapy
3.5
12.6
44
131
SPAT1139
SPAT
Nutrition survey
3.9
12.5
37
98
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
+∞
12.5
12
*
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
20.3
12.5
18
9
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
131.6
12.5
13
*
S63.1
ICD-10 Finland
Dislocation of finger
5.4
12.3
24
45
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
12.3
268
1747
S00.9
ICD-10 Finland
Superficial injury of head, part unspecified
10.7
12.3
23
22
R30.1
ICD-10 Finland
Vesical tenesmus
5.2
12.3
25
49
ACC51
NOMESCO Finland
Release of median nerve
38.0
12.2
15
*
SPAT1244
SPAT
Occupational therapy
18.3
12.1
18
10
SPAT1260
SPAT
Consultation of another employee
1.9
12.1
162
911
N03AX14
ATC
levetiracetam; systemic
21.6
12.0
17
8
R5140
NOMESCO Finland
Monitoring the use of the aid
3.1
11.9
51
172
C03CA01
ATC
furosemide; systemic
1.6
11.8
422
3122
R4120, ,
SPAT
12.7
11.7
20
16
R4130, ,
SPAT
65.7
11.6
13
*
F34.1
ICD-10 Finland
Dysthymia
65.7
11.6
13
*
N04BX01
ATC
tolcapone; oral
+∞
11.5
11
*
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
+∞
11.5
11
*
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
+∞
11.5
11
*
F0029, G308,
ICD-10 Finland
+∞
11.5
11
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
11.5
11
*
N04BC01
ATC
bromocriptine; oral
+∞
11.5
11
*
I63.8
ICD-10 Finland
Other cerebral infarction
+∞
11.5
11
*
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
+∞
11.5
11
*
J01MA02
ATC
ciprofloxacin; systemic
1.6
11.5
375
2709
A03FA01
ATC
metoclopramide; systemic, rectal
0.4
11.5
75
1580
F99
ICD-10 Finland
Mental disorder, not otherwise specified
121.4
11.4
12
*
N05AX12
ATC
aripiprazole; systemic
121.4
11.4
12
*
M01AC06
ATC
meloxicam; systemic, rectal
1.7
11.4
283
1906
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.3
11.4
89
407
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
4.2
11.4
30
73
SPAT1279
SPAT
Preparation of immediate hospitalisation
5.5
11.4
22
41
S01.3
ICD-10 Finland
Open wound of ear
12.0
11.4
20
17
R2110
NOMESCO Finland
Giving the first information
2.8
11.3
58
217
S01.8
ICD-10 Finland
Open wound of other parts of head
4.8
11.2
25
53
H02AB02
ATC
dexamethasone; systemic
0.3
11.2
26
898
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.5
11.2
38
111
W17
ICD-10 Finland
Other fall from one level to another
3.5
11.2
39
116
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
0.1
11.1
*
336
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
11.1
342
2432
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.8
11.0
34
93
SPAT1101
SPAT
Orthostatic test
2.9
11.0
52
186
A02BC05
ATC
esomeprazole; systemic
1.6
11.0
318
2224
N18
ICPC
Paralysis/weakness
14.1
11.0
18
13
R44.3
ICD-10 Finland
Hallucinations, unspecified
43.8
10.9
13
*
R29.6
ICD-10 Finland
Tendency to fall, not elsewhere classified
43.8
10.9
13
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.9
10.9
50
176
Z02.7
ICD-10 Finland
Issue of medical certificate
2.7
10.9
60
233
S01
ICD-10 Finland
Open wound of head
8.4
10.8
23
28
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.1
10.8
*
327
F32.1
ICD-10 Finland
Moderate depressive episode
28.4
10.7
14
5
S09.9
ICD-10 Finland
Unspecified injury of head
5.6
10.7
20
36
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
10.7
169
999
G04BD07
ATC
tolterodine; oral
2.7
10.7
57
218
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
60.7
10.6
12
*
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
4.7
10.5
24
52
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
4.7
10.5
24
52
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
+∞
10.4
10
*
F06.2
ICD-10 Finland
Organic delusional [schizophrenia-like] disorder
+∞
10.4
10
*
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
+∞
10.4
10
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
+∞
10.4
10
*
F0231, G20,
ICD-10 Finland
+∞
10.4
10
*
OAB76
NOMESCO Finland
General guidance on nutrition and food
+∞
10.4
10
*
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
10.4
111
575
R5130, ,
SPAT
16.2
10.4
16
10
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.8
10.4
53
198
N03AX09
ATC
lamotrigine; oral
32.9
10.3
13
*
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
32.9
10.3
13
*
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
19.0
10.3
15
8
NF3AA
NOMESCO Finland
Femur X-ray examination
3.6
10.3
33
93
S00.1
ICD-10 Finland
Contusion of eyelid and periocular area
4.9
10.0
22
46
F32
ICD-10 Finland
Depressive episode
9.3
10.0
20
22
H50.52
ICD-10 Finland
Exophoria
10.2
10.0
19
19
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
10.0
325
2327
M01AH02
ATC
rofecoxib; oral
2.0
10.0
124
677
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
3.9
10.0
29
76
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.4
10.0
67
287
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
16.9
9.9
15
9
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
9.9
118
636
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
4.4
9.8
24
55
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
9.8
109
573
ZXD05
NOMESCO Finland
Urgent procedure
1.6
9.8
258
1755
N05AB03
ATC
perphenazine; systemic, rectal
13.5
9.7
16
12
F29
ICD-10 Finland
Unspecified nonorganic psychosis
55.5
9.7
11
*
IGY02
NOMESCO Finland
Psychiatric monitoring contact
55.5
9.7
11
*
A02BC01
ATC
omeprazole; systemic
1.6
9.6
247
1669
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
8.5
9.6
20
24
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
9.2
9.5
19
21
M79.6
ICD-10 Finland
Pain in limb
1.6
9.5
307
2192
H53.2
ICD-10 Finland
Diplopia
3.7
9.4
30
84
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
101.0
9.4
10
*
G30.0
ICD-10 Finland
Alzheimer disease with early onset
101.0
9.4
10
*
N05AF03
ATC
chlorprothixene; systemic
30.3
9.4
12
*
WX780
NOMESCO Finland
Remote monitoring CPAP
+∞
9.4
9
*
F41.09
ICD-10 Finland
UNS Panic Syndrome
+∞
9.4
9
*
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
+∞
9.4
9
*
G21.8
ICD-10 Finland
Other secondary parkinsonism
+∞
9.4
9
*
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
+∞
9.4
9
*
N04AA01
ATC
trihexyphenidyl; oral
+∞
9.4
9
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
9.4
256
1755
N06AG02
ATC
moclobemide; oral
4.0
9.4
26
66
E0000UV, ,
ATC
1.6
9.4
326
2366
L01BC06
ATC
capecitabine; oral
0.1
9.1
*
310
M03BX01
ATC
baclofen; systemic
15.7
9.0
14
9
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.5
9.0
30
87
G25.2
ICD-10 Finland
Other specified forms of tremor
18.8
8.9
13
7
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
24.3
8.9
12
5
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
4.0
8.9
25
64
XQ855, ,
SPAT
4.9
8.9
19
39
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.7
8.8
27
74
G04BD04
ATC
oxybutynin; oral, transdermal
2.4
8.7
60
260
S01.41
ICD-10 Finland
Open wound in the temple-jaw region
7.7
8.7
19
25
R1430, ,
SPAT
7.7
8.7
19
25
NB6AA
NOMESCO Finland
Humerus X-ray examination
3.8
8.7
26
70
N40
ICD-10 Finland
Hyperplasia of prostate
1.5
8.6
324
2383
G04BD10
ATC
darifenacin; oral
11.7
8.6
15
13
Z3231
NOMESCO Finland
Registered nurse
1.6
8.6
242
1668
RF120, ,
NOMESCO Finland
9.1
8.6
17
19
N05BE01
ATC
buspirone; oral
10.1
8.5
16
16
L84
ICD-10 Finland
Corns and callosities
3.0
8.5
36
121
M03BC01
ATC
orphenadrine (citrate); systemic
1.9
8.5
115
646
N17
ICPC
Vertigo/dizziness
1.9
8.5
117
661
F43.29
ICD-10 Finland
Adaptation disorder UNS
27.8
8.5
11
*
R4110
NOMESCO Finland
Physiotherapy
1.6
8.4
246
1708
N05AN01
ATC
lithium; oral
90.8
8.4
9
*
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
90.8
8.4
9
*
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
90.8
8.4
9
*
K11.72
ICD-10 Finland
Xerostomia
90.8
8.4
9
*
ZXA00
NOMESCO Finland
Right side
1.6
8.4
249
1735
TPH04, ,
SPAT
4.9
8.4
18
37
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.7
8.4
19
41
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
8.3
8
*
G81.9
ICD-10 Finland
Hemiplegia, unspecified
+∞
8.3
8
*
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
+∞
8.3
8
*
N04BC07
ATC
apomorphine; parenteral
+∞
8.3
8
*
G23.8
ICD-10 Finland
Other specified degenerative diseases of basal ganglia
+∞
8.3
8
*
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
+∞
8.3
8
*
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
2.8
8.3
42
156
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
0.1
8.2
*
310
S80.0
ICD-10 Finland
Contusion of knee
2.6
8.2
45
175
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
8.2
8.1
17
21
OAB41
NOMESCO Finland
Guidance and counselling related to ageing
33.6
8.1
10
*
F32.8
ICD-10 Finland
Other depressive episodes
33.6
8.1
10
*
ZY000
NOMESCO Finland
Hospital inpatient
33.6
8.1
10
*
Z29
ICPC
Social problem NOS
6.4
8.0
20
32
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.0
8.0
83
425
G56.2
ICD-10 Finland
Lesion of ulnar nerve
22.2
8.0
11
5
N08
ICPC
Abnormal involuntary movements
22.2
8.0
11
5
L03
ICPC
Low back symptom/complaint
1.6
8.0
187
1230
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.2
7.9
66
311
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
7.9
471
3788
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
3.3
7.8
29
90
S50.0
ICD-10 Finland
Contusion of elbow
3.7
7.8
24
66
SPAT1138
SPAT
Guidance concerning bowel function
4.4
7.7
19
44
L12.0
ICD-10 Finland
Bullous pemphigoid
7.5
7.7
17
23
S28
ICPC
Limited function/disability (S)
8.1
7.6
16
20
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
12.0
7.6
13
11
M54
ICD-10 Finland
Dorsalgia
2.0
7.6
77
392
R1100, ,
SPAT
6.2
7.6
19
31
PA6AD
NOMESCO Finland
CT of neck arteries
4.5
7.4
18
41
P76
ICPC
Depressive disorder
6.5
7.4
18
28
G55.2
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
80.7
7.4
8
*
S06.3
ICD-10 Finland
Focal brain injury
80.7
7.4
8
*
LAITO, ,
NOMESCO Finland
80.7
7.4
8
*
H50.31
ICD-10 Finland
Intermittent exotropia
13.5
7.4
12
9
L02
ICPC
Back symptom/complaint
2.2
7.4
62
293
N05CF02
ATC
zolpidem; oral
1.9
7.4
99
555
WYA20, ,
SPAT
6.9
7.3
17
25
F0009, G300,
ICD-10 Finland
+∞
7.3
7
*
AA052, ,
NOMESCO Finland
+∞
7.3
7
*
G31.0
ICD-10 Finland
Circumscribed brain atrophy
+∞
7.3
7
*
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
7.3
7
*
F02.33
ICD-10 Finland
Dementia in Parkinson's disease other additional symptoms, mainly depression
+∞
7.3
7
*
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
+∞
7.3
7
*
IGY99
NOMESCO Finland
Other psychiatric treatment contact
+∞
7.3
7
*
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
+∞
7.3
7
*
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
+∞
7.3
7
*
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
+∞
7.3
7
*
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.3
7.3
27
84
EBA00
NOMESCO Finland
Extraction of tooth
1.5
7.2
262
1900
WX320
NOMESCO Finland
Spinalanesthesy
1.5
7.2
231
1631
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
3.7
7.2
22
60
M47.9
ICD-10 Finland
Spondylosis, unspecified
3.6
7.2
23
65
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
2.7
7.1
37
140
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
12.1
7.1
12
10
SPAT1246
SPAT
Screening of depression or other psychiatric problem
8.9
7.1
14
16
M43.1
ICD-10 Finland
Spondylolisthesis
3.1
7.1
28
91
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.9
7.1
86
467
WF049
NOMESCO Finland
Radiotherapy of metastasis
0.1
7.1
*
281
E87.6
ICD-10 Finland
Hypokalaemia
2.6
7.0
38
147
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.5
7.0
44
183
Z50.1
ICD-10 Finland
Other physical therapy
2.3
7.0
49
215
R5140, ,
SPAT
6.4
7.0
17
27
K56.2
ICD-10 Finland
Volvulus
6.4
7.0
17
27
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
2.9
6.9
31
108
H02BX01
ATC
methylprednisolone, combinations; systemic
2.2
6.9
55
254
SPAT1252
SPAT
Overall medication plan or its review
2.1
6.9
67
335
N30
ICD-10 Finland
Cystitis
2.2
6.9
56
261
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.4
6.9
24
72
M03BX02
ATC
tizanidine; oral
1.4
6.8
376
2955
J01CA04
ATC
amoxicillin; systemic
1.4
6.8
646
5598
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.8
6.8
106
623
K02.1
ICD-10 Finland
Caries of dentine
1.4
6.8
367
2875
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
40.3
6.8
8
*
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
40.3
6.8
8
*
R40.0
ICD-10 Finland
Somnolence
40.3
6.8
8
*
A08.1
ICD-10 Finland
Acute gastroenteropathy due to Norovirus
16.8
6.8
10
6
W10
ICD-10 Finland
Fall on and from stairs and steps
2.6
6.8
39
156
L99
ICPC
Musculoskeletal disease other
3.5
6.7
22
63
L76
ICPC
Fracture: other
2.9
6.7
31
110
W06
ICD-10 Finland
Fall involving bed
7.2
6.7
15
21
UDQ42
NOMESCO Finland
Endoscopic assessment of swallowing function
22.7
6.7
9
*
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
22.7
6.7
9
*
G04CB02
ATC
dutasteride; oral
1.7
6.7
113
680
XKC03
NOMESCO Finland
Water cystometry
3.2
6.6
26
84
F03
ICPC
Eye discharge
2.3
6.6
51
233
SAD02
NOMESCO Finland
Assessment of need for oral health care, extensive
3.2
6.6
25
79
G43.9
ICD-10 Finland
Migraine, unspecified
12.3
6.6
11
9
G45.4
ICD-10 Finland
Transient global amnesia
10.1
6.5
12
12
A08
ICPC
Swelling
2.1
6.5
57
274
A02BC02
ATC
pantoprazole; systemic
1.4
6.5
581
4958
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
6.2
6.5
16
26
L29
ICPC
Musculoskeletal sympt/complt other
2.0
6.5
71
372
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
70.3
6.4
7
*
R26
ICD-10 Finland
Abnormalities of gait and mobility
70.3
6.4
7
*
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
70.3
6.4
7
*
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
70.3
6.4
7
*
AA1AM
NOMESCO Finland
Short MRI examination of brain with 3 Tesla magnet
70.3
6.4
7
*
G72.9
ICD-10 Finland
Myopathy, unspecified
70.3
6.4
7
*
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
70.3
6.4
7
*
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.7
6.4
133
845
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
14.4
6.4
10
7
F41.1
ICD-10 Finland
Generalized anxiety disorder
14.4
6.4
10
7
ZX120, ,
SPAT
4.1
6.4
17
42
S70.1
ICD-10 Finland
Contusion of thigh
4.1
6.4
17
42
N80
ICPC
Head injury other
4.1
6.4
17
42
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.5
6.4
79
1360
N03AF01
ATC
carbamazepine; oral, rectal
3.1
6.3
25
81
WF002
NOMESCO Finland
Radical radiotherapy
0.2
6.3
11
451
R07.3
ICD-10 Finland
Other chest pain
1.9
6.3
75
404
359
Kela drug reimbursment
Mirabegroni
11.1
6.3
11
10
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
9.3
6.3
12
13
K08.3
ICD-10 Finland
Retained dental root
2.0
6.3
69
362
F009, G309,
ICD-10 Finland
+∞
6.3
6
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
+∞
6.3
6
*
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
+∞
6.3
6
*
IBZ07
NOMESCO Finland
Neurological assessment in psychiatry
+∞
6.3
6
*
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
+∞
6.3
6
*
S06.2
ICD-10 Finland
Diffuse brain injury
+∞
6.3
6
*
N88
ICPC
Epilepsy
+∞
6.3
6
*
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
+∞
6.3
6
*
G47.0
ICD-10 Finland
Disorders of initiating and maintaining sleep [insomnias]
+∞
6.3
6
*
F06.32
ICD-10 Finland
Organic depression
+∞
6.3
6
*
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
+∞
6.3
6
*
WX723
NOMESCO Finland
CPAP therapy
+∞
6.3
6
*
AAW01
NOMESCO Finland
Implantation of intracranial stimulation device
+∞
6.3
6
*
F0019, G301,
ICD-10 Finland
+∞
6.3
6
*
Z60.8
ICD-10 Finland
Other problems related to social environment
26.9
6.2
8
*
OAB48
NOMESCO Finland
Lifestyle advice and guidance
26.9
6.2
8
*
A06AX04
ATC
linaclotide; oral
26.9
6.2
8
*
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
26.9
6.2
8
*
SCA02
NOMESCO Finland
Preventive oral health care
2.1
6.2
59
293
R50.9
ICD-10 Finland
Fever, unspecified
1.7
6.2
119
741
S00.8
ICD-10 Finland
Superficial injury of other parts of head
5.1
6.2
18
36
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
3.6
6.2
20
57
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
1.7
6.2
117
726
AA1AA
NOMESCO Finland
Head X-ray examination
6.3
6.2
15
24
SPAT1014
SPAT
Treatment of eyes
3.4
6.2
21
62
N02BF01
ATC
gabapentin; oral
2.1
6.1
56
274
B03BA03
ATC
hydroxocobalamin; parenteral
2.0
6.1
66
344
X50
ICD-10 Finland
Overexertion and strenuous or repetitive movements
4.2
6.1
16
39
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
12.6
6.1
10
8
Z51.5
ICD-10 Finland
Palliative care
1.7
6.1
124
785
-, ,
ICD-10 Finland
3.1
6.1
24
78
SPAT1127
SPAT
Enema
6.7
6.0
14
21
K89
ICPC
Transient cerebral ischaemia
10.1
6.0
11
11
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.9
6.0
28
100
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.5
6.0
20
58
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
3.9
6.0
17
44

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
421
1779
3.37
74.09
2.9
1.8
298.16
184.15
u/l
1.80
398
1644
350
1355
3.45
70.44
2.1
1.6
1081.70
1136.62
nmol/l
0.51
248
989
490
2475
2.94
60.18
4.9
3.1
—
—
—
0
0
707
4945
2.50
37.01
7.8
4.4
4081.26
3328.19
e6/l
0.08
23
72
430
2433
2.35
36.84
4.3
4.2
—
—
—
0
0
406
2276
2.33
35.15
2.0
1.7
16.87
19.67
nmol/l
3.85
362
1833
538
3528
2.15
30.19
2.6
2.1
82.81
92.71
pmol/l
6.89
340
1785
31
27
11.82
30.15
1.3
1.1
1.74
25.89
e6/l
0.58
23
19
31
28
11.40
29.45
1.6
1.2
226.84
19.14
e6/l
0.57
25
21
35
39
9.27
28.73
4.8
3.1
—
—
—
0
0
582
4005
2.10
27.89
5.6
7.3
1.21
1.21
mmol/l
1.80
482
3422
294
1559
2.26
27.85
1.9
1.7
384.57
22097199.55
pmol/l
1.30
238
1240
32
36
9.15
26.06
1.4
1.2
—
—
—
0
0
452
2916
2.01
24.95
5.6
3.8
46.41
74.20
ng/l
1.20
386
2362
353
2189
1.95
20.95
2.2
2.3
2.68
2.96
mg/l
1.65
278
1849
605
4470
1.91
20.91
5.2
4.6
6.39
6.89
mmol/l
12.14
585
4235
533
3788
1.88
20.72
6.0
3.7
10.28
4.43
estimate
0.24
145
897
510
3577
1.88
20.64
4.9
6.4
1.20
1.20
mmol/l
0.14
461
3296
534
3833
1.85
19.76
6.0
3.8
0.03
0.00
estimate
0.44
141
832
71
215
3.48
19.75
2.0
2.4
383.00
433.57
ug/l
0.13
66
209
373
2396
1.89
19.62
4.1
3.3
0.54
0.56
e6/l
0.05
295
1794
435
2943
1.85
19.35
4.7
3.3
6.31
6.24
ph
0.64
239
1565
521
3728
1.84
19.31
6.0
3.7
0.00
0.00
estimate
-0.00
140
861
283
1689
1.95
18.38
4.1
3.0
603.67
542.65
mosm/kgh2o
5.22
249
1461
407
2742
1.82
18.00
4.3
3.4
44.62
141.79
e6/l
1.31
327
2118
369
2428
1.83
17.53
2.7
4.4
7.41
7.40
ph
7.02
283
1733
499
3600
1.78
17.30
3.7
5.1
33.88
34.07
g/l
0.29
446
3327
342
2207
1.84
17.25
4.1
3.3
0.70
1096.88
estimate
—
5
14
407
2773
1.79
17.11
6.3
3.9
0.03
0.02
estimate
0.02
117
699
174
2960
0.50
15.35
3.0
3.4
47.46
49.49
mg/l
0.05
113
1905
175
2965
0.50
15.22
3.1
3.3
7.16
7.07
mmol/l
0.12
138
2419
160
2781
0.49
14.98
1.6
1.9
1.07
1.22
mmol/l
3.08
133
2206
422
3002
1.71
14.59
5.1
3.9
130.15
152.05
e6/l
0.24
331
2179
417
2962
1.70
14.46
2.3
2.2
71.83
81.38
nmol/l
10.42
344
2561
296
1922
1.77
14.09
6.1
3.5
0.01
0.01
estimate
0.10
110
623
228
1372
1.86
13.95
3.7
3.3
2.39
1.65
e6/l
0.73
125
755
523
3992
1.66
13.45
14.9
19.5
1.31
1.39
inr
2.42
452
3349
107
504
2.26
12.80
1.6
2.6
409.19
413.37
nmol/l
0.07
84
469
235
1474
1.78
12.38
3.7
3.2
1.05
1.07
e6/l
0.02
134
854
195
3035
0.56
12.09
3.9
4.1
7.02
8.81
mg/mmol
0.41
125
1890
284
1890
1.70
12.09
3.3
2.6
4.99
4.93
e6/l
0.03
260
1689
600
4840
1.61
11.56
3.9
3.8
15.52
15.20
pmol/l
2.03
518
4207
37
107
3.55
11.07
1.5
2.5
23.67
34.81
umol/l
3.57
30
99
308
2155
1.62
10.56
6.0
3.7
0.00
0.01
estimate
0.78
116
750
241
1599
1.67
10.13
5.5
3.8
1.02
1.02
kg/l
1.30
171
1094
396
2979
1.55
9.78
2.6
3.0
159.91
182.03
ug/l
0.85
335
2692
268
1861
1.60
9.29
4.6
3.1
0.08
0.00
0.47
13
78
13
7
18.79
8.94
1.1
1.1
131.69
120.71
nmol/l
—
13
7
54
222
2.51
8.77
4.9
4.5
25.64
24.73
mmol/l
1.34
45
193
169
1061
1.71
8.62
2.0
2.0
29.73
30.28
s
0.61
160
1034
96
506
1.99
8.56
4.1
4.2
—
—
—
0
0
33
106
3.19
8.44
1.4
1.2
—
—
—
0
0
777
6877
1.60
8.36
26.9
17.2
30.65
30.98
mg/l
0.09
726
5662
116
660
1.86
8.24
2.8
4.4
1.22
1.22
mmol/l
0.12
95
571
14
12
11.81
8.09
1.4
1.2
—
—
—
0
0
197
1308
1.63
8.08
1.7
3.1
0.83
0.82
mmol/l
0.71
178
1227
120
698
1.82
7.94
2.5
2.3
5.93
7.07
ug/l
0.43
64
627
145
892
1.73
7.93
2.6
3.6
7.38
7.37
ph
1.25
96
552
97
539
1.89
7.42
5.3
5.8
25.30
24.17
mmol/l
2.28
91
515
445
3586
1.44
7.14
3.3
2.9
53.38
63.83
u/l
0.72
402
3189
224
1577
1.54
7.08
4.5
3.9
148.95
676.06
ng/l
2.62
205
1420
300
2253
1.48
6.94
2.6
2.4
53.34
63.09
u/l
1.93
276
2056
70
358
2.03
6.81
2.4
1.8
—
—
—
0
0
159
1042
1.63
6.81
4.3
6.4
1.75
0.74
mmol/l
3.52
133
845
62
1173
0.50
6.77
3.3
4.7
2.90
31.35
ug/l
3.05
46
1001
158
1039
1.62
6.67
4.3
6.5
7.42
7.41
ph
0.96
104
558
129
813
1.67
6.43
1.8
1.8
—
—
—
0
0
15
23
6.60
6.35
1.2
1.0
—
—
—
0
0
700
6195
1.44
6.28
5.3
4.6
1.93
2.19
mu/l
5.77
610
5389
18
47
3.88
6.28
1.3
1.1
326.36
336.61
nmol/l
0.06
11
33
134
861
1.64
6.20
2.7
3.6
2.50
1.59
mmol/l
2.47
118
714
156
1047
1.58
6.03
4.3
6.5
5.08
5.06
kpa
0.09
149
1001
156
1047
1.58
6.03
4.3
6.5
11.53
12.01
kpa
0.54
148
1004
170
1164
1.56
6.02
1.7
2.3
1.57
1.74
%
1.80
139
1024
339
2663
1.41
6.00
2.3
4.1
2.33
2.35
mmol/l
1.10
299
2351
78
439
1.84
5.76
4.3
4.2
7.43
7.42
ph
0.89
66
363
79
447
1.83
5.73
4.3
4.2
5.21
5.08
kpa
0.61
70
421
225
1652
1.47
5.70
2.6
3.5
2.46
2.47
mmol/l
1.53
195
1453
658
5805
1.40
5.67
5.7
8.6
82.90
85.33
u/l
0.47
595
5437
100
610
1.71
5.63
7.4
3.7
—
—
—
0
0
51
251
2.09
5.54
3.9
3.5
1.61
1.68
mmol/l
0.18
51
246
5
0
+∞
5.21
11.6
0.0
0.74
—
mmol/l
—
5
0
35
155
2.30
4.94
3.3
4.6
1.85
2.67
mmol/l
1.19
26
102
485
4141
1.33
4.79
3.8
7.3
12.17
13.64
umol/l
2.09
448
3949
135
931
1.52
4.60
4.3
6.8
95.80
95.19
%
0.78
129
899
602
6676
0.75
4.53
4.1
5.1
1.41
1.44
mmol/l
0.98
516
5883
47
245
1.96
4.42
6.3
5.3
1.08
1.41
mmol/l
2.37
42
224
405
3398
1.32
4.40
5.2
6.2
8.57
9.34
%
5.98
369
3160
315
2551
1.34
4.35
4.9
5.9
—
—
—
0
0
404
3394
1.32
4.33
4.9
6.1
2.44
2.85
%
3.55
368
3160
7
6
11.74
4.28
1.0
1.0
—
—
%
—
0
0
10
341
0.29
4.27
1.0
1.2
—
—
—
0
0
611
6740
0.76
4.26
4.1
5.2
4.19
4.39
mmol/l
5.05
526
5994
54
302
1.83
4.13
5.0
4.4
—
—
—
0
0
200
1521
1.39
4.08
1.8
2.6
11.29
11.93
umol/l
0.78
171
1424
403
3408
1.31
4.04
5.1
6.1
0.57
0.65
%
2.84
365
3171
398
3362
1.31
4.02
5.2
6.0
62.95
59.06
%
8.76
370
3189
190
1437
1.40
4.00
1.8
2.6
2.13
2.23
g/l
1.30
156
1333
10
18
5.60
3.98
1.0
1.9
64.03
54.22
ug/l
—
10
18
575
6371
0.77
3.97
3.6
4.3
1.11
1.22
mmol/l
4.21
481
5538
51
870
0.56
3.95
1.1
1.4
—
—
—
0
0
432
3700
1.30
3.90
5.1
5.8
1.56
1.82
e9/l
4.19
378
3155
313
2577
1.31
3.76
2.3
2.8
—
—
—
0
0
111
767
1.50
3.76
1.7
2.1
0.20
0.19
g/l
0.42
99
711
405
3453
1.29
3.74
5.2
6.1
22.27
25.38
%
7.34
378
3243
434
3734
1.29
3.74
5.2
5.9
0.16
0.20
e9/l
6.51
372
3131
0
95
0.00
3.68
0.0
1.1
—
—
—
0
0
84
555
1.56
3.50
4.2
2.8
5.95
5.95
ph
0.01
64
415
126
914
1.43
3.35
1.8
2.4
59.55
66.59
e9/l
1.57
94
678
419
3625
1.27
3.34
4.9
5.8
0.59
0.64
e9/l
3.65
355
3001
186
1444
1.35
3.31
1.7
1.5
1.56
1.87
mg/l
0.48
148
1144
419
3642
1.26
3.17
4.9
5.8
0.04
0.04
e9/l
4.54
355
3017
115
831
1.43
3.13
2.9
2.8
198.43
287.41
ng/l
1.43
106
762
641
6926
0.79
3.10
4.8
6.1
2.36
2.52
mmol/l
5.04
549
6137
19
80
2.40
3.07
3.0
1.9
0.89
0.68
u/field
—
9
34
411
3583
1.25
2.98
2.7
3.1
—
—
estimate
—
0
0
237
1936
1.29
2.94
3.7
3.9
78.82
81.35
%
0.89
232
1894
100
714
1.45
2.91
2.8
2.4
0.65
0.43
e6/l
0.40
100
695
173
1360
1.33
2.83
1.9
2.5
21.57
21.70
%
0.04
145
1265
752
7041
1.28
2.82
24.2
16.1
—
—
—
0
0
87
610
1.47
2.79
3.6
3.0
—
—
—
0
0
47
286
1.68
2.77
7.8
3.9
—
—
—
0
0
187
2290
0.77
2.56
2.8
3.7
0.76
0.90
ug/l
0.99
129
1694
38
621
0.60
2.56
1.8
2.1
11.92
12.12
nmol/l
0.05
30
528
101
741
1.40
2.55
5.1
4.6
7.36
7.35
ph
0.03
72
522
141
1097
1.33
2.48
1.2
1.2
0.62
1.88
u/ml
2.29
32
242
84
603
1.43
2.41
1.6
3.0
—
—
—
0
0
62
419
1.51
2.40
1.9
1.8
1.37
1.87
ug/l
0.35
43
373
261
3052
0.80
2.39
2.2
2.4
—
—
—
0
0
34
557
0.60
2.33
1.4
1.4
—
—
—
0
0
43
269
1.63
2.32
1.5
1.2
—
—
—
0
0
344
3005
1.22
2.32
3.2
3.2
1462.76
1987.74
ng/l
1.78
297
2680
11
40
2.77
2.28
1.1
1.1
—
—
—
0
0
12
47
2.57
2.27
1.3
1.2
—
—
—
0
0
781
7409
1.25
2.25
31.1
21.5
139.81
139.56
mmol/l
1.69
764
7205
29
489
0.58
2.23
1.3
1.4
—
—
—
0
0
27
463
0.57
2.21
1.5
1.6
—
—
—
0
0
781
7413
1.25
2.21
31.1
21.8
3.96
4.03
mmol/l
9.58
763
7201
8
199
0.40
2.17
1.0
1.4
—
—
—
0
0
110
843
1.34
2.15
1.8
2.7
9.58
12.98
umol/l
0.80
95
743
251
2143
1.23
2.09
2.2
3.0
36.85
38.22
u/l
0.07
229
1991
10
37
2.72
2.07
1.6
1.5
—
—
—
0
0
26
441
0.58
2.06
2.2
3.5
108.36
6506.86
u/ml
1.39
21
377
28
162
1.75
2.04
1.4
1.5
23405.11
14408.15
e6/l
0.27
19
115
68
931
0.71
2.00
1.2
1.2
68.83
45.43
iu/ml
0.35
25
282
31
186
1.69
1.99
2.5
3.7
—
—
—
0
0
162
1960
0.79
1.98
4.1
3.8
—
—
—
0
0
463
4208
1.19
1.97
6.4
10.1
4.71
4.36
e9/l
1.88
395
3570
91
688
1.36
1.96
2.6
2.0
0.00
0.02
estimate
0.50
16
135
48
695
0.67
1.93
1.3
1.3
247.27
553.54
titre
2.77
11
161
23
128
1.82
1.91
1.4
1.7
2.37
4.57
iu/l
—
7
40
87
665
1.34
1.77
2.2
2.4
30.72
38.73
u/l
0.78
68
556
601
5615
1.18
1.76
30.4
22.9
13.78
14.01
%
4.44
591
5497
21
358
0.58
1.73
1.3
1.3
—
—
—
0
0
781
7471
1.21
1.73
32.1
24.6
73.82
87.82
umol/l
51.28
765
7329
27
163
1.67
1.73
1.2
1.8
0.69
0.82
%
1.09
17
113
5
13
3.86
1.71
1.2
1.2
—
—
—
0
0
5
13
3.86
1.71
1.6
2.1
62.40
665.31
nmol/24h
—
5
13
0
48
0.00
1.70
0.0
2.3
—
36.43
—
0
48
783
7497
1.21
1.69
36.5
27.0
232.45
234.35
e9/l
0.37
757
7243
783
7497
1.21
1.69
36.4
26.9
30.54
30.52
pg
0.13
764
7337
783
7497
1.21
1.69
36.4
26.9
92.33
92.09
fl
0.80
764
7336
783
7497
1.21
1.69
36.8
27.5
37.92
39.39
%
10.59
764
7333
783
7497
1.21
1.69
36.4
27.0
4.20
4.37
e12/l
18.10
756
7204
783
7498
1.21
1.68
36.8
27.2
126.71
132.34
g/l
24.39
764
7343
783
7498
1.21
1.68
36.5
27.0
6.95
6.94
e9/l
0.05
755
7202
576
5378
1.17
1.66
31.2
24.3
330.42
330.85
g/l
0.54
562
5328
6
148
0.40
1.64
1.2
1.4
—
—
—
0
0
42
286
1.49
1.64
2.3
2.5
—
24.05
—
0
25
29
183
1.60
1.58
6.8
3.1
21.09
29.53
mg/l
1.11
24
136
20
115
1.75
1.53
1.2
1.2
—
—
—
0
0
0
42
0.00
1.53
0.0
1.1
—
—
—
0
0
13
65
2.01
1.49
1.5
1.2
275.25
274.57
mosm/kgh2o
—
8
46
67
870
0.75
1.45
1.3
1.2
12.66
21.08
u/ml
0.46
24
267
174
2019
0.83
1.41
2.1
3.1
334.65
370.69
umol/l
3.59
136
1711
0
38
0.00
1.34
0.0
2.1
—
0.48
—
0
38
0
38
0.00
1.34
0.0
1.4
—
51507.09
—
0
22
0
39
0.00
1.34
0.0
1.6
—
529.89
—
0
28
45
327
1.39
1.30
2.0
2.2
0.00
0.12
estimate
0.56
16
95
131
1100
1.22
1.30
2.5
5.5
0.97
1.05
mmol/l
3.85
119
1026
21
329
0.63
1.29
1.2
1.8
—
30.12
—
0
9
72
566
1.29
1.26
2.2
2.0
197.64
150.96
ug/g
0.55
55
437
62
793
0.77
1.23
1.4
1.3
—
—
—
0
0
7
145
0.48
1.20
1.1
1.2
—
4.00
—
0
10
221
1961
1.16
1.18
2.3
2.7
—
—
—
0
0
11
57
1.94
1.17
1.4
2.1
16.75
15.38
%
0.77
11
57
0
34
0.00
1.16
0.0
1.7
—
—
—
0
0
0
36
0.00
1.14
0.0
2.4
—
63.61
—
0
36
57
446
1.29
1.06
2.5
2.4
—
—
—
0
0
29
204
1.43
1.04
1.4
1.4
307.00
251.57
ug/g
0.56
18
130
62
773
0.79
1.03
1.2
1.4
—
—
—
0
0
102
1205
0.83
1.03
1.4
1.4
—
—
—
0
0
39
290
1.36
1.03
2.4
3.3
4.33
4.35
pmol/l
0.05
31
251
23
155
1.50
1.01
1.1
1.1
—
—
—
0
0
5
108
0.46
1.01
1.0
1.1
—
—
—
0
0
32
231
1.40
1.00
2.1
3.3
3.07
1.56
index
0.55
15
111
18
273
0.65
1.00
1.2
1.3
—
—
—
0
0
95
797
1.21
0.99
1.5
3.1
65.68
65.67
g/l
0.00
75
734
127
1098
1.18
0.96
1.8
1.9
—
—
—
0
0
0
32
0.00
0.95
0.0
1.2
—
—
—
0
0
9
51
1.77
0.94
1.3
2.0
11.27
8.38
mmol/l
—
9
51
73
599
1.24
0.94
2.6
3.5
78.04
100.41
ng/l
1.74
56
515
6
120
0.50
0.93
1.0
1.2
—
—
—
0
0
10
168
0.59
0.87
1.1
1.6
0.22
0.22
g/l
—
10
158
46
579
0.78
0.86
1.3
1.4
—
—
—
0
0
644
6674
0.90
0.85
6.7
7.0
39.76
40.21
mmol/mol
0.66
562
5994
27
196
1.39
0.85
12.8
11.4
—
—
—
0
0
14
88
1.60
0.84
1.6
1.1
—
—
—
0
0
11
65
1.70
0.82
2.1
1.5
—
—
—
0
0
0
25
0.00
0.79
0.0
2.3
—
5.40
—
0
25
0
25
0.00
0.79
0.0
2.3
—
30.20
—
0
25
553
5299
1.10
0.77
4.8
4.6
—
0.25
—
0
16
11
172
0.64
0.74
1.1
1.6
1.15
1.10
g/l
0.29
11
161
9
56
1.61
0.72
1.9
2.1
291.22
281.57
mu/l
—
9
56
14
206
0.68
0.72
1.2
1.5
33.08
30.37
g/l
0.34
14
192
9
146
0.61
0.69
1.1
1.1
—
—
—
0
0
5
94
0.53
0.67
1.2
2.5
356.40
827.00
mg
—
5
94
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
16
112
1.44
0.63
1.4
1.3
—
—
—
0
0
26
199
1.31
0.63
1.6
1.6
33.94
31.84
u/ml
—
7
38
12
79
1.53
0.62
1.2
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.5
—
—
—
0
0
10
150
0.66
0.58
1.3
1.6
—
—
—
0
0
6
35
1.72
0.57
1.2
3.5
1.00
0.83
index
—
6
35
10
65
1.54
0.55
1.5
1.8
9.56
10.23
%
—
10
65
36
438
0.82
0.55
1.2
1.3
—
—
—
0
0
12
82
1.47
0.54
2.3
3.3
19.83
11.43
index
—
6
35
669
6855
0.93
0.53
5.0
5.7
6.01
6.08
mmol/l
0.70
562
5982
84
745
1.14
0.51
3.5
7.7
—
—
—
0
0
11
75
1.47
0.51
1.8
2.0
—
—
—
0
0
51
439
1.17
0.47
2.2
3.2
—
—
—
0
0
11
153
0.72
0.45
1.1
1.4
—
—
—
0
0
5
85
0.59
0.45
1.0
1.1
—
—
—
0
0
5
85
0.59
0.45
1.0
1.4
—
—
—
0
0
39
330
1.19
0.44
1.3
2.5
9.10
10.95
g/l
3.19
27
293
64
721
0.88
0.42
2.8
4.2
1.46
0.77
%
0.34
13
248
0
16
0.00
0.41
0.0
2.9
—
1981.13
—
0
16
0
17
0.00
0.40
0.0
1.6
—
47.21
—
0
11
0
17
0.00
0.40
0.0
1.3
—
0.48
—
0
6
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
35
297
1.18
0.40
2.5
3.3
140.43
290.16
mg/l
2.91
14
138
7
101
0.69
0.39
1.1
1.2
—
—
—
0
0
9
66
1.37
0.38
1.3
1.2
—
—
nmol/l
—
0
0
9
69
1.31
0.37
1.2
1.1
—
—
—
0
0
69
763
0.90
0.36
2.7
4.1
0.54
0.97
%
0.94
13
259
5
77
0.65
0.35
1.0
1.2
—
—
—
0
0
150
1406
1.08
0.35
4.1
4.7
—
—
—
0
0
6
43
1.40
0.35
1.0
1.2
—
—
—
0
0
6
45
1.34
0.33
1.5
1.8
—
—
—
0
0
17
210
0.81
0.33
1.8
2.4
34.20
86.53
ug/min
—
8
114
31
359
0.86
0.32
1.3
1.3
—
—
—
0
0
11
143
0.77
0.32
2.8
2.8
—
—
—
0
0
51
568
0.89
0.31
1.4
1.5
—
—
—
0
0
392
3806
1.05
0.30
4.5
6.8
2.88
4.92
ug/l
2.98
326
3384
34
388
0.87
0.30
1.4
1.2
—
—
—
0
0
11
141
0.78
0.29
1.1
1.4
—
—
—
0
0
10
77
1.30
0.26
1.1
1.6
19.50
29.77
ng/l
—
10
77
9
74
1.22
0.25
1.4
1.4
—
—
—
0
0
86
920
0.93
0.25
1.2
1.3
—
—
—
0
0
55
505
1.09
0.23
1.6
1.7
1.42
1.51
g/l
0.37
45
428
68
731
0.93
0.22
2.7
4.1
0.08
0.16
%
0.41
12
227
15
125
1.20
0.22
2.1
3.1
4.98
4.19
e9/l
0.45
15
125
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
10
80
1.25
0.20
1.4
1.2
0.54
0.22
nmol/l
—
5
5
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
48
1.25
0.20
2.5
2.4
—
—
—
0
0
345
3375
1.03
0.18
15.0
11.9
0.00
0.00
e9/l
4.36
279
2711
37
342
1.09
0.15
1.2
4.2
2.00
8.42
ratio
1.43
22
223
24
265
0.90
0.15
1.1
1.1
71.14
144.25
u/ml
—
7
76
10
118
0.85
0.14
1.7
1.8
—
—
—
0
0
29
267
1.09
0.13
1.2
4.6
—
—
—
0
0
742
7368
1.03
0.13
10.2
12.6
16.73
23.92
u/l
26.76
673
7011
15
169
0.89
0.12
1.5
1.6
8.89
12.78
mg/l
1.98
15
150
79
823
0.96
0.12
3.2
6.3
10.15
12.61
mmol/l
2.79
70
782
24
220
1.09
0.12
1.1
1.8
—
—
—
0
0
100
1034
0.96
0.11
1.2
1.6
2.26
3.04
g/l
3.25
43
583
201
2052
0.97
0.11
1.2
1.3
—
—
—
0
0
69
718
0.96
0.10
2.8
4.4
0.00
0.17
%
1.73
12
217
5
48
1.04
0.09
1.0
1.0
—
—
—
0
0
6
54
1.11
0.09
1.0
2.2
—
—
—
0
0
12
107
1.12
0.08
1.3
1.1
—
—
—
0
0
5
61
0.82
0.08
1.0
1.1
—
—
—
0
0
5
64
0.78
0.08
1.2
1.1
—
—
—
0
0
12
109
1.10
0.06
3.0
2.6
—
—
—
0
0
16
168
0.95
0.02
1.8
2.4
60.92
62.39
%
0.11
16
168
224
2250
0.99
0.01
6.3
6.8
—
—
—
0
0
84
832
1.01
0.01
2.8
3.1
4.80
4.58
e9/l
0.24
59
687
38
384
0.99
0.00
1.3
4.4
44.59
212.35
mg/l
0.66
28
338
15
152
0.99
0.00
2.2
3.3
57.40
58.11
%
0.07
15
152
10
97
1.03
0.00
1.7
4.8
—
—
—
0
0
38
383
0.99
0.00
1.3
4.4
45.87
64.85
mg/l
0.37
27
341
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
73.67
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
28.00
—
0
9
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
20.2
—
102.83
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.03
—
0
5
7
70
1.00
-0.00
3.1
1.9
30.00
38.74
mg/l
—
7
50
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
91
0.99
-0.00
2.6
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
39.14
—
0
7
0
5
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.60
—
0
5
8
88
0.91
-0.00
1.1
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint PD_DEMENTIA_EXMORE and mortality.

Females

Parameter HR [95% CI] p-value
PD_DEMENTIA_EXMORE 4.002 [3.47, 4.62] < 0.001
Birth year 0.996 [0.99, 1.0] 0.35

During the follow-up period (1.1.1998 — 31.12.2019), 2678 out of 3661 females with PD_DEMENTIA_EXMORE died.

Males

Parameter HR [95% CI] p-value
PD_DEMENTIA_EXMORE 4.506 [3.75, 5.41] < 0.001
Birth year 0.99 [0.98, 1.0] 0.032

During the follow-up period (1.1.1998 — 31.12.2019), 3543 out of 4687 males with PD_DEMENTIA_EXMORE died.

Mortality risk

Mortality risk for people of age

years, who have PD_DEMENTIA_EXMORE.

N-year risk Females Males
1 0.287% 1.034%
5 2.261% 5.714%
10 5.45% 13.843%
15 10.744% 24.757%
20 18.651% 38.964%

Relationships between endpoints

Index endpoint: PD_DEMENTIA_EXMORE – Dementia due to Parkinsons disease, excluding more controls

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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