Small fibre neuropathy

SFN

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

1273

4. Check minimum number of events

None

1273

5. Include endpoints

None

1273

6. Filter based on genotype QC (FinnGen only)

1124

Control definitions (FinnGen only)

Control exclude
G6_POLYNEU

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4420 1835 2568
Only index persons 4164 1744 2420
Unadjusted period prevalence (%)
Whole population 0.06 0.05 0.07
Only index persons 0.08 0.06 0.09
Median age at first event (years)
Whole population 63.93 64.22 63.77
Only index persons 63.81 64.02 63.66

-FinnGen-

Key figures

All Female Male
Number of individuals 1124 497 627
Unadjusted period prevalence (%) 0.24 0.18 0.29
Median age at first event (years) 65.45 64.05 66.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1157
Matched controls
11570
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G62.8
ICD-10 Finland
Other specified polyneuropathies
16384.0
307.7
1092
6
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
237.1
307.7
543
43
N03AX12
ATC
[U] gabapentin; oral
6.6
214.9
495
1172
N06AX21
ATC
duloxetine; oral
6.5
172.4
354
735
N03AX16
ATC
[U] pregabalin
5.1
165.2
554
1758
R20.2
ICD-10 Finland
Paraesthesia of skin
7.2
136.6
231
389
N02BF01
ATC
gabapentin; oral
5.5
127.7
302
699
N02BF02
ATC
pregabalin; oral
6.7
122.4
219
389
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
43.6
103.4
62
15
TAB00
NOMESCO Finland
Lumbar puncture
7.1
92.2
150
239
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.7
79.3
209
517
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
5.4
77.0
166
346
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.6
71.2
296
1012
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
22.6
70.5
52
24
G60.8
ICD-10 Finland
Other hereditary and idiopathic neuropathies
+∞
67.4
64
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.7
63.6
236
744
N06AX16
ATC
venlafaxine; oral
3.5
62.5
264
905
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.9
60.3
145
330
N28
ICPC
Limited function/disability (N)
9.1
57.3
72
84
L28
ICPC
Limited function/disability (L)
2.9
54.9
341
1454
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
7.5
52.6
78
111
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
51.5
475
2459
R52.2
ICD-10 Finland
Other chronic pain
5.2
48.9
106
220
N03AX09
ATC
lamotrigine; oral
5.2
48.9
107
224
N99
ICPC
Neurological disease other
10.1
48.6
56
58
N29
ICPC
Neurological sympt/complt other
7.9
48.4
68
91
N04BC05
ATC
pramipexole; oral
3.7
47.3
166
499
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.0
47.1
254
993
AA1AD
NOMESCO Finland
CT of head and brain
2.5
47.0
480
2582
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
46.9
723
4670
N06AA09
ATC
amitriptyline; systemic
3.5
46.3
183
594
M79.6
ICD-10 Finland
Pain in limb
2.4
45.6
630
3858
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
6.5
45.6
77
126
N03AE01
ATC
clonazepam; systemic
4.3
45.5
126
319
G61.8
ICD-10 Finland
Other inflammatory polyneuropathies
+∞
43.0
41
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.2
42.0
186
646
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
6.5
39.8
67
109
G72.9
ICD-10 Finland
Myopathy, unspecified
12.6
38.6
38
31
L17
ICPC
Foot/toe symptom/complaint
2.3
38.0
455
2568
M48.0
ICD-10 Finland
Spinal stenosis
2.8
37.7
231
958
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.3
37.4
159
537
G60.0
ICD-10 Finland
Hereditary motor and sensory neuropathy
379.1
37.2
37
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
36.8
348
1772
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
36.2
311
1516
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.4
35.8
140
449
R52.1
ICD-10 Finland
Chronic intractable pain
11.2
35.7
38
35
N02AX02
ATC
tramadol; systemic, rectal
2.1
34.8
604
3910
R53
ICD-10 Finland
Malaise and fatigue
2.3
34.1
364
1942
A01
ICPC
Pain general/multiple sites
2.9
34.1
178
676
A02BC02
ATC
pantoprazole; systemic
2.3
33.3
883
6695
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.9
33.2
178
685
R4110
NOMESCO Finland
Physiotherapy
2.2
33.0
409
2314
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.2
32.9
91
229
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
32.7
464
2764
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.5
32.2
236
1063
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
6.7
32.2
52
81
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.0
32.0
162
604
G64
ICD-10 Finland
Other disorders of peripheral nervous system
61.8
31.2
36
6
G61.9
ICD-10 Finland
Inflammatory polyneuropathy, unspecified
164.4
30.8
32
*
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
7.7
30.3
43
58
N06AX11
ATC
mirtazapine; oral
2.1
30.2
458
2779
A28
ICPC
Limited function/disability NOS
2.3
30.0
281
1410
H02AB06
ATC
prednisolone; systemic
2.0
29.8
622
4224
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.6
29.8
104
309
A07AA02
ATC
nystatin; oral
3.5
29.5
107
326
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.8
29.4
168
667
H02AB09
ATC
hydrocortisone; systemic
5.7
29.2
55
100
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
29.0
248
1194
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
28.9
216
979
ZX120
NOMESCO Finland
Intravenous
2.8
28.7
158
615
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
28.7
188
800
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
28.5
464
2874
R4120
NOMESCO Finland
Occupational therapy
3.2
28.2
119
398
J01FF01
ATC
clindamycin; systemic
2.1
28.1
379
2190
J01MA02
ATC
ciprofloxacin; systemic
2.0
27.2
519
3383
G61.0
ICD-10 Finland
Guillain-Barré syndrome
277.2
26.8
27
*
N02AA05
ATC
oxycodone; systemic
2.2
26.6
285
1503
XA402
NOMESCO Finland
ENMG
5.3
26.4
54
106
C03CA01
ATC
furosemide; systemic
2.0
26.3
420
2566
R50.9
ICD-10 Finland
Fever, unspecified
2.3
26.3
235
1149
R42
ICD-10 Finland
Dizziness and giddiness
2.1
26.3
329
1841
R35
ICD-10 Finland
Polyuria
2.9
26.2
131
483
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.0
25.9
124
446
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.9
25.9
78
209
N05BA04
ATC
oxazepam; oral
2.1
25.7
347
1994
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
25.4
324
1823
S97
ICPC
Chronic ulcer skin
3.0
25.3
120
429
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
25.0
220
1066
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
5.4
25.0
50
96
R51.80
ICD-10 Finland
Headache
2.3
25.0
213
1019
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
24.7
169
731
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.4
24.7
193
888
R52.9
ICD-10 Finland
Pain, unspecified
2.6
24.6
165
707
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.1
24.5
108
370
H04.10
ICD-10 Finland
Dry eye syndrome
2.5
24.2
176
783
UKC02
NOMESCO Finland
Cystoscopy
2.2
23.8
253
1323
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
23.8
363
2169
UJF32
NOMESCO Finland
Coloscopy
2.0
23.7
368
2211
L04AX01
ATC
azathioprine; systemic
3.8
23.5
73
200
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
23.5
181
827
Z50.1
ICD-10 Finland
Other physical therapy
3.2
22.9
96
319
TK800
NOMESCO Finland
Hemodialysis
4.9
22.8
51
108
M54.1
ICD-10 Finland
Radiculopathy
3.7
22.7
75
214
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
22.7
391
2427
N03AF01
ATC
carbamazepine; oral, rectal
3.3
22.6
90
290
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
22.4
528
3618
N05CF01
ATC
zopiclone; oral
1.9
22.2
407
2574
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
21.9
378
2342
N05AH04
ATC
quetiapine; oral
2.2
21.9
232
1208
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
81.7
21.7
24
*
C08CA05
ATC
nifedipine; systemic
3.1
21.7
95
324
Z3226
NOMESCO Finland
Physiotherapist
2.1
21.6
250
1346
R60.0
ICD-10 Finland
Localized oedema
2.3
21.2
193
944
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
21.2
177
835
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
21.1
556
3918
A02BC05
ATC
esomeprazole; systemic
1.8
21.1
503
3442
L04AA06
ATC
mycophenolic acid; systemic
5.1
20.8
44
89
M54.5
ICD-10 Finland
Low back pain
1.8
20.6
452
3010
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
6.6
20.5
33
51
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
5.5
20.5
40
75
Z3231
NOMESCO Finland
Registered nurse
1.9
20.2
353
2187
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
20.2
350
2163
A41.9
ICD-10 Finland
Sepsis, unspecified
3.7
19.9
65
184
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
19.8
406
2640
H02AB04
ATC
methylprednisolone; systemic
2.2
19.6
195
988
S18
ICPC
Laceration/cut
1.8
19.5
612
4503
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.8
19.5
105
402
R13
ICD-10 Finland
Dysphagia
2.6
19.4
117
474
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
19.3
224
1203
C07AB07
ATC
bisoprolol; oral
1.8
19.3
628
4664
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.6
19.3
31
48
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.4
19.1
48
112
K59.09
ICD-10 Finland
Constipation, unspecified
2.6
19.1
114
460
G62.0
ICD-10 Finland
Drug-induced polyneuropathy
56.0
19.0
22
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.7
18.8
107
421
WX002
NOMESCO Finland
Sedation and analgesia
2.0
18.8
262
1501
A02BC01
ATC
omeprazole; systemic
1.9
18.7
336
2091
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
5.0
18.6
40
82
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.8
18.4
56
151
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.7
18.3
107
427
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
18.2
190
978
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.3
18.2
72
231
R39.1
ICD-10 Finland
Other difficulties with micturition
3.5
18.1
64
191
127
Kela drug reimbursment
Transplant complication
5.4
18.0
36
69
H02AB07
ATC
prednisone; oral
2.1
17.7
181
924
N02BE01
ATC
paracetamol; systemic, rectal
2.5
17.6
1060
9402
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.6
17.6
104
417
N06AB04
ATC
citalopram; systemic
1.9
17.6
253
1461
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
17.6
179
913
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
17.5
239
1357
R20.8
ICD-10 Finland
Other and unspecified disturbances of skin sensation
6.9
17.5
27
40
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.2
17.4
70
227
R1250
NOMESCO Finland
Evaluation of functional capability
4.0
17.4
49
125
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
5.4
17.4
34
64
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
17.3
261
1530
ZXD05
NOMESCO Finland
Urgent procedure
1.8
17.3
371
2426
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.8
17.2
54
149
M79.1
ICD-10 Finland
Myalgia
2.1
17.2
192
1014
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
17.0
352
2275
J01DB01
ATC
cefalexin; oral
2.0
17.0
966
8291
N30.0
ICD-10 Finland
Acute cystitis
2.0
17.0
199
1068
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.3
17.0
141
661
SPAT1229
SPAT
Assessment of need for aid
2.5
17.0
112
474
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
16.9
450
3123
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
16.9
246
1424
J02AC01
ATC
fluconazole; systemic
1.7
16.9
408
2756
ZY010
NOMESCO Finland
Hospital outpatient
3.0
16.8
76
264
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
16.7
169
859
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.5
16.7
109
459
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.4
16.7
121
535
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
16.6
237
1362
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
16.6
496
3549
J01EA01
ATC
trimethoprim; systemic
1.8
16.6
284
1733
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
16.4
281
1712
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
16.4
187
993
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
3.8
16.4
51
140
G44.2
ICD-10 Finland
Tension-type headache
2.1
16.3
171
880
ZXA05
NOMESCO Finland
Left side
1.8
16.2
308
1939
N18
ICPC
Paralysis/weakness
4.3
16.1
42
101
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
16.1
210
1170
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.4
16.1
114
499
E0000UV, ,
ATC
1.7
16.0
483
3453
N03AF02
ATC
oxcarbazepine; oral
3.5
15.9
55
162
R06.0
ICD-10 Finland
Dyspnoea
1.7
15.8
359
2374
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.3
15.8
135
640
P01BA02
ATC
hydroxychloroquine; oral
2.5
15.8
106
452
N94
ICPC
Peripheral neuritis/neuropathy
60.9
15.8
18
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.0
15.8
45
116
R11
ICD-10 Finland
Nausea and vomiting
2.4
15.8
118
529
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.7
15.6
90
356
M47.9
ICD-10 Finland
Spondylosis, unspecified
3.4
15.6
57
174
Z31.5
ICD-10 Finland
Genetic counselling
3.0
15.6
69
237
G04BD12
ATC
mirabegron; oral
2.0
15.6
177
939
G63.2
ICD-10 Finland
Diabetic polyneuropathy
38.6
15.4
19
5
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.2
15.4
133
634
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.3
15.4
130
614
M03BX01
ATC
baclofen; systemic
4.4
15.3
39
92
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
15.3
235
1380
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.4
15.3
114
510
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.8
15.1
76
280
N06AB10
ATC
escitalopram; oral
1.9
15.1
228
1333
Z2446
NOMESCO Finland
Social worker
2.6
15.0
93
382
JN4BD
NOMESCO Finland
Extensive body CT
2.1
14.9
149
752
K59.0
ICD-10 Finland
Constipation
2.7
14.9
85
335
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
14.8
515
3798
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.7
14.8
84
330
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
16.7
14.8
23
14
D07AC01
ATC
betamethasone; topical
1.7
14.7
436
3088
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.3
14.7
38
91
G04CA02
ATC
tamsulosin; oral
1.7
14.6
346
2306
H53.2
ICD-10 Finland
Diplopia
3.2
14.6
59
192
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.5
14.5
94
394
M79.7
ICD-10 Finland
Fibromyalgia
3.5
14.4
49
143
JN4AD
NOMESCO Finland
Body CT examination
2.0
14.3
174
943
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.3
14.3
112
511
Z49.1
ICD-10 Finland
Extracorporeal dialysis
4.9
14.3
31
64
G56.2
ICD-10 Finland
Lesion of ulnar nerve
3.1
14.2
59
195
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
14.1
115
535
W19
ICD-10 Finland
Unspecified fall
2.2
14.1
131
643
M25.5
ICD-10 Finland
Pain in joint
1.7
14.0
389
2701
R27.0
ICD-10 Finland
Ataxia, unspecified
12.9
13.9
24
19
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
13.8
319
2107
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
3.3
13.8
53
167
R06AE07
ATC
cetirizine; oral
1.6
13.8
471
3440
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.0
13.8
39
100
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.5
13.7
88
367
A04
ICPC
Weakness/tiredness general
1.9
13.6
192
1094
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.7
13.6
76
296
B03BA03
ATC
hydroxocobalamin; parenteral
2.6
13.6
78
308
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
6.0
13.6
24
41
N06
ICPC
Sensation disturbance other
6.0
13.6
24
41
6BA02, ,
NOMESCO Finland
34.5
13.5
17
5
G62
ICD-10 Finland
Other polyneuropathies
141.6
13.5
14
*
A46
ICD-10 Finland
Erysipelas
1.9
13.5
200
1159
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
13.4
203
1183
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.1
13.4
141
725
XKD00
NOMESCO Finland
Uroflowmetry
1.8
13.4
226
1363
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
13.4
139
712
C07AA05
ATC
propranolol; systemic
1.8
13.3
231
1404
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.9
13.3
65
236
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.9
13.3
64
231
R33
ICD-10 Finland
Retention of urine
2.2
13.2
120
583
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.3
13.1
49
152
SPAT1301
SPAT
No procedures
1.7
13.1
362
2501
B03XA02
ATC
darbepoetin alfa; parenteral
3.7
13.1
42
118
M03BX02
ATC
tizanidine; oral
1.6
13.0
696
5625
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
13.0
55
184
J01MA14
ATC
moxifloxacin; systemic
2.1
13.0
123
607
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
4.3
13.0
33
78
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.7
12.9
71
275
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.5
12.9
44
129
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.9
12.8
165
911
WW200
NOMESCO Finland
Immunization
3.4
12.8
46
139
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
12.8
350
2411
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.3
12.8
102
470
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.7
12.7
68
259
R26.2
ICD-10 Finland
Difficulty in walking, not elsewhere classified
4.4
12.7
32
75
NF1AA
NOMESCO Finland
Hip X-ray examination
2.1
12.7
127
641
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.8
12.6
38
102
R25.1
ICD-10 Finland
Tremor, unspecified
3.2
12.6
50
161
A06AD11
ATC
lactulose; oral
1.9
12.6
184
1060
SPAT1216
SPAT
Assessment of functional ability
1.8
12.6
200
1183
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.3
12.6
47
146
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.4
12.6
89
389
B01AB05
ATC
enoxaparin; parenteral
1.6
12.5
382
2700
N06AX22
ATC
agomelatine; oral
4.0
12.5
35
89
ZXA00
NOMESCO Finland
Right side
1.7
12.5
318
2147
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.4
12.5
84
359
N17
ICPC
Vertigo/dizziness
1.9
12.4
167
935
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.5
12.4
42
122
R01AD08
ATC
fluticasone; nasal
1.7
12.4
310
2082
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.1
12.4
52
173
F61.0
ICD-10 Finland
Mixed personality disorders
4.9
12.4
27
56
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
12.4
233
1449
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
4.0
12.1
34
87
N05BA01
ATC
diazepam; systemic, rectal
1.9
12.0
159
885
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.7
12.0
66
255
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
10.2
12.0
23
23
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.2
12.0
103
489
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
5.7
12.0
22
39
N05
ICPC
Tingling fingers/feet/toes
5.7
12.0
22
39
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.2
11.9
47
151
A10AB05
ATC
insulin aspart; parenteral
2.2
11.9
105
504
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.8
11.9
36
97
Z71.9
ICD-10 Finland
Counselling, unspecified
2.2
11.8
109
532
Z2221
NOMESCO Finland
Medical doctor
1.6
11.8
311
2113
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
11.8
141
758
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
11.8
238
1507
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
11.8
229
1435
A02BA02
ATC
ranitidine; systemic
1.7
11.8
229
1436
N06AA10
ATC
nortriptyline; systemic
3.7
11.7
37
103
L29
ICPC
Musculoskeletal sympt/complt other
2.1
11.6
117
591
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.8
11.6
35
94
SPAT1260
SPAT
Consultation of another employee
1.8
11.5
209
1283
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
11.5
421
3093
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
11.5
171
989
S29
ICPC
Skin symptom/complaint other
1.7
11.5
245
1575
NXL00
NOMESCO Finland
Biopsy of muscle
13.8
11.5
19
14
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.9
11.5
150
832
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.0
11.4
132
701
R20.1
ICD-10 Finland
Hypoaesthesia of skin
11.9
11.3
20
17
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.1
11.3
47
156
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
11.3
255
1664
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.1
11.3
46
151
J01CF05
ATC
flucloxacillin; systemic
2.2
11.3
101
488
Z71.8
ICD-10 Finland
Other specified counselling
1.6
11.2
381
2748
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.6
11.2
21
38
M01AB55
ATC
diclofenac, combinations; oral
2.3
11.2
86
390
L04AD01
ATC
ciclosporin; systemic
3.9
11.2
32
83
A04AA01
ATC
ondansetron; systemic, rectal
2.1
11.1
111
559
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.6
11.1
64
254
D12
ICPC
Constipation
2.7
11.0
60
231
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
5.8
11.0
20
35
R03AC02
ATC
salbutamol; inhalant
1.5
11.0
607
4861
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.4
11.0
40
122
TKC20
NOMESCO Finland
Catheterisation of bladder
2.2
11.0
94
445
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
4.6
11.0
26
58
NJ3CG
NOMESCO Finland
Extensive MRI examination of extremities with median high magnet
14.0
11.0
18
13
XW000
NOMESCO Finland
Bone marrow biopsy
2.6
10.9
63
250
137
Kela drug reimbursment
Uraemia requiring dialysis
5.5
10.9
21
39
R5110, ,
SPAT
2.0
10.9
120
627
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.0
10.8
126
671
D07AB08
ATC
desonide; topical
2.0
10.8
130
700
I73.0
ICD-10 Finland
Raynaud syndrome
4.4
10.8
27
63
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.2
10.8
97
469
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
10.8
103
510
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.0
10.8
46
155
N06AX26
ATC
vortioxetine; oral
2.3
10.8
86
396
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.9
10.8
133
723
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
10.8
238
1542
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.7
10.7
56
211
M54.3
ICD-10 Finland
Sciatica
2.3
10.7
80
358
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.9
10.6
50
178
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
10.6
214
1351
JAH00
NOMESCO Finland
Laparotomy
3.0
10.6
47
162
WX892
NOMESCO Finland
Monitored bed care
2.1
10.6
108
549
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
10.5
424
3166
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.9
10.5
148
840
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
10.5
143
803
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.0
10.5
47
163
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
10.4
232
1504
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.4
10.4
75
330
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.7
10.4
57
220
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.8
10.4
53
197
P01AB01
ATC
metronidazole; oral, rectal
1.5
10.4
434
3265
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.8
10.4
52
192
L04AA13
ATC
[U] leflunomide
3.5
10.3
35
102
XA800
NOMESCO Finland
Neuropsychological investigation
2.6
10.3
60
239
P03
ICPC
Feeling depressed
2.1
10.3
100
498
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
10.3
377
2755
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
10.3
135
749
V03AE01
ATC
polystyrene sulfonate; oral
4.1
10.3
28
70
G72.8
ICD-10 Finland
Other specified myopathies
3.9
10.3
30
79
G62.1
ICD-10 Finland
Alcoholic polyneuropathy
23.6
10.3
14
6
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.3
10.2
75
333
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.2
10.2
39
123
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.0
10.2
109
563
R5599
NOMESCO Finland
Other rehabilitation service
3.1
10.2
43
144
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.5
10.2
62
253
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.7
10.1
53
200
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
10.1
578
4633
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.5
10.1
64
266
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.3
10.1
77
348
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.5
10.1
63
260
Z94.0
ICD-10 Finland
Kidney transplant status
5.1
10.1
21
42
SPAT1167
SPAT
Insertion of urinary catheter
2.9
10.1
47
167
J01CA08
ATC
pivmecillinam; oral
1.5
10.0
366
2669
B81
ICPC
Anaemia vit B12/folate deficiency
2.7
10.0
55
213
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.1
10.0
94
463
A11CC03
ATC
alfacalcidol; systemic
3.2
9.9
38
120
A02BA04
ATC
nizatidine; systemic
2.1
9.9
94
464
K56.7
ICD-10 Finland
Ileus, unspecified
3.8
9.9
30
81
NHQ40
NOMESCO Finland
Amputation of toe
3.8
9.9
30
81
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.4
9.9
66
281
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.9
9.8
125
687
L14
ICPC
Leg/thigh symptom/complaint
2.0
9.8
104
536
R07.3
ICD-10 Finland
Other chest pain
1.9
9.8
134
754
H93.1
ICD-10 Finland
Tinnitus
2.1
9.8
93
460
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
9.8
404
3024
M47.82
ICD-10 Finland
Other spondylosis, cervical region
2.6
9.7
58
234
A03FA02
ATC
cisapride; oral, rectal
2.1
9.7
88
427
R03BA02
ATC
budesonide; inhalant
1.7
9.7
200
1269
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.9
9.7
44
154
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
9.7
226
1482
S06.0
ICD-10 Finland
Concussion
1.9
9.6
137
780
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
4.0
9.6
27
69
A06AC51
ATC
ispaghula, combinations; oral
2.4
9.6
63
266
N18.0
ICD-10 Finland
End-stage renal disease
4.8
9.6
21
44
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
9.6
151
888
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
3.6
9.5
31
88
ACC53
NOMESCO Finland
Release of ulnar nerve
4.1
9.5
26
65
S91.1
ICD-10 Finland
Open wound of toe(s) without damage to nail
4.1
9.5
26
65
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.0
9.5
101
520
R4130
NOMESCO Finland
Speech therapy
3.0
9.5
41
139
WX882
NOMESCO Finland
High dependency care
3.0
9.5
41
139
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.2
9.5
37
118
N03AX14
ATC
levetiracetam; systemic
2.9
9.5
43
150
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.3
9.5
74
338
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.9
9.5
120
658
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
3.1
9.5
39
129
N06AX03
ATC
mianserin; oral
2.4
9.5
62
262
SPAT1099
SPAT
Measurement of blood pressure with Doppler ultrasound device
2.8
9.4
47
173
M04AA01
ATC
allopurinol; systemic
1.7
9.4
170
1039
G58.7
ICD-10 Finland
Mononeuritis multiplex
100.8
9.4
10
*
G12.8
ICD-10 Finland
Other spinal muscular atrophies and related syndromes
30.3
9.4
12
*
A05AA02
ATC
ursodeoxycholic acid; oral
4.3
9.4
24
57
G60.9
ICD-10 Finland
Hereditary and idiopathic neuropathy, unspecified
+∞
9.4
9
*
ZXA10
NOMESCO Finland
Bilateral
1.7
9.4
211
1370
H57.1
ICD-10 Finland
Ocular pain
2.7
9.4
50
191
H26.4
ICD-10 Finland
After-cataract
1.9
9.3
126
705
C10AC01
ATC
colestyramine; oral
3.1
9.3
39
130
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.0
9.3
106
560
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
3.7
9.3
29
80
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.1
9.3
85
414
N30.9
ICD-10 Finland
Cystitis, unspecified
2.2
9.3
79
374
SPAT1172
SPAT
Guidance concerning hydration
3.6
9.3
30
85
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
3.4
9.2
32
95
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.7
9.2
164
999
R03BA08
ATC
ciclesonide; inhalant
2.0
9.2
102
534
XF600
NOMESCO Finland
Bloodpressure measurement
2.2
9.2
81
389
N05CD07
ATC
temazepam; oral
1.8
9.2
137
792
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.0
9.2
104
549
M05BA04
ATC
alendronic acid; oral
2.0
9.1
98
507
N06AX12
ATC
bupropion; oral
2.2
9.1
73
337
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.9
9.1
41
143
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
9.1
223
1479
K11.70
ICD-10 Finland
Hypoptyalism
11.6
9.1
16
14
M54.2
ICD-10 Finland
Cervicalgia
2.0
9.0
100
523
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
9.1
9.0
18
20
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
9.0
418
3191
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
3.0
8.9
38
128
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
8.9
795
6882
A01AB09
ATC
miconazole; local oral
2.0
8.9
96
497
N05BA12
ATC
alprazolam; oral
1.9
8.9
115
634
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
8.9
191
1223
SPAT1211
SPAT
Application of soft bandage
2.0
8.9
104
555
N04BC04
ATC
ropinirole; oral
4.9
8.9
19
39
N06AG02
ATC
moclobemide; oral
2.5
8.8
56
233
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.5
8.8
365
2720
GBB00
NOMESCO Finland
Tracheostomy
4.1
8.8
24
60
L16
ICPC
Ankle symptom/complaint
1.8
8.8
141
832
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.4
8.8
31
93
TQW40
NOMESCO Finland
Remowal of suture of skin
2.1
8.8
88
444
Z2445
NOMESCO Finland
Psychologist
2.7
8.8
47
180
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
7.2
8.8
20
28
J01MA12
ATC
levofloxacin; systemic
1.6
8.7
224
1500
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.5
8.7
52
210
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
8.7
59
253
K30
ICD-10 Finland
Functional dyspepsia
1.8
8.7
129
743
XPX04
NOMESCO Finland
Angioscopy
14.2
8.7
14
10
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
8.7
156
952
GD1AD
NOMESCO Finland
Thorax CT examination
2.0
8.7
93
481
S01GX01
ATC
cromoglicic acid; ophthalmic
1.7
8.7
195
1264
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
3.8
8.6
26
70
A02BC03
ATC
lansoprazole; oral
1.5
8.6
321
2338
WZC30
NOMESCO Finland
Teaching
1.6
8.6
197
1282
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
4.6
8.6
20
44
E86
ICD-10 Finland
Volume depletion
3.0
8.6
38
131
R61.9
ICD-10 Finland
Hyperhidrosis, unspecified
4.8
8.6
19
40
R03DC03
ATC
montelukast; oral
1.7
8.6
174
1097
N18.8
ICD-10 Finland
Other chronic renal failure
3.2
8.6
34
110
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
10.1
8.5
16
16
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.4
8.5
60
262
M43.1
ICD-10 Finland
Spondylolisthesis
2.5
8.5
53
219
R63.4
ICD-10 Finland
Abnormal weight loss
2.4
8.5
58
250
WX402
NOMESCO Finland
General anaesthesia
1.6
8.5
255
1772
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.9
8.4
113
631
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
8.4
113
632
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.4
8.4
29
86
SFA20
NOMESCO Finland
Two-surface restoration
1.4
8.4
631
5259
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
3.8
8.4
25
67
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
4.7
8.4
19
41
G60.3
ICD-10 Finland
Idiopathic progressive neuropathy
+∞
8.3
8
*
Z01.2
ICD-10 Finland
Dental examination
1.4
8.3
490
3901
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
2.6
8.3
47
185
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
8.3
87
446
R60.9
ICD-10 Finland
Oedema, unspecified
2.1
8.3
74
357
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.3
8.3
64
291
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
9.5
8.3
16
17
Z50.5
ICD-10 Finland
Speech therapy
4.1
8.3
22
54
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.2
8.3
32
102
SPAT1254
SPAT
Administration of medicine
1.7
8.3
164
1028
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.6
8.2
46
180
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
3.3
8.2
30
92
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
8.2
175
1117
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
2.5
8.2
49
198
R4180
NOMESCO Finland
Podiatric therapy
3.7
8.2
25
68
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.8
8.2
40
146
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.2
8.2
68
319
XF602
NOMESCO Finland
Bloodpressure monitoring
4.4
8.2
20
46
SAA04
NOMESCO Finland
Special examination of mouth
2.2
8.2
67
313
I95.1
ICD-10 Finland
Orthostatic hypotension
2.4
8.1
55
236
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.8
8.1
39
141
D07AD01
ATC
clobetasol; topical
1.6
8.1
184
1194
R03AC03
ATC
terbutaline; inhalant
1.7
8.1
146
891
RD210, ,
NOMESCO Finland
3.8
8.1
24
64
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
2.8
8.1
40
147
N05CF02
ATC
zolpidem; oral
1.6
8.1
188
1228
L60.0
ICD-10 Finland
Ingrowing nail
2.3
8.1
63
288
Z00.8
ICD-10 Finland
Other general examinations
2.0
8.1
94
501
A02BC04
ATC
rabeprazole; oral
1.9
8.1
102
559
A11
ICPC
Chest pain NOS
1.9
8.1
110
618
C08CA13
ATC
lercanidipine; oral
1.7
8.0
177
1140
L04AX03
ATC
methotrexate; systemic
1.9
8.0
109
611
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.1
8.0
32
104
WW500
NOMESCO Finland
Blood transfusion
2.5
8.0
51
213
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.9
8.0
23
60
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.5
8.0
49
201
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
7.3
8.0
18
25
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.3
8.0
57
251
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.8
8.0
114
650
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
8.0
53
226
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
4.3
8.0
20
47
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
4.3
8.0
20
47
K65.0
ICD-10 Finland
Acute peritonitis
4.3
8.0
20
47
L03
ICPC
Low back symptom/complaint
1.5
7.9
314
2311
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.0
7.9
35
121
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.1
7.9
76
378
Z49.0
ICD-10 Finland
Preparatory care for dialysis
4.7
7.9
18
39
L12
ICPC
Hand/finger symptom/complaint
1.6
7.9
190
1252
R10.2
ICD-10 Finland
Pelvic and perineal pain
3.2
7.9
31
100
P01
ICPC
Feeling anxious/nervous/tense
1.9
7.9
103
571
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.4
7.8
27
80
L19
ICPC
Muscle symptom/complaint NOS
2.8
7.8
39
144
SPAT1263
SPAT
Sampling
1.4
7.8
440
3463
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
3.8
7.8
23
61
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
7.8
412
3204
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.2
7.8
64
299
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
7.0
7.8
18
26
M01AH01
ATC
celecoxib; oral
1.6
7.8
194
1289
N30.1
ICD-10 Finland
Interstitial cystitis (chronic)
4.2
7.8
20
48
XCK00
NOMESCO Finland
Perimetry
2.1
7.7
71
347
TK810
NOMESCO Finland
Hemofiltration
6.4
7.7
19
30
Z02.7
ICD-10 Finland
Issue of medical certificate
2.0
7.7
89
473
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
2.7
7.7
40
151
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
7.7
591
4914
H03AA01
ATC
levothyroxine sodium; systemic
1.6
7.7
232
1611
G47.3
ICD-10 Finland
Sleep apnoea
1.5
7.7
281
2034
SPAT1125
SPAT
Stoma care and guidance
3.8
7.6
23
62
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.6
701
6009
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.2
7.6
62
289
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.0
7.6
85
447
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.4
7.6
52
225
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
3.8
7.5
22
58
J01FA10
ATC
azithromycin; systemic
1.4
7.5
578
4797
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
7.5
103
579
J05AB11
ATC
valaciclovir; oral
1.7
7.5
162
1037
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
2.7
7.5
40
153
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.1
7.5
31
103
J01DA01
ATC
[U] cefalexin
1.4
7.5
659
5598
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
4.3
7.5
19
45
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
3.6
7.4
24
68
RS222, ,
NOMESCO Finland
4.4
7.4
18
41
G04CA01
ATC
alfuzosin; oral
1.6
7.4
173
1129
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
7.4
235
1647
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
3.2
7.4
28
88
U07
ICPC
Urine symptom/complaint other
1.8
7.4
103
582
A12AA04
ATC
calcium carbonate; oral
3.4
7.4
26
78
R52.0
ICD-10 Finland
Acute pain
2.6
7.4
43
172
M60.8
ICD-10 Finland
Other myositis
13.5
7.4
12
9
C88.0
ICD-10 Finland
Waldenström macroglobulinaemia
13.5
7.4
12
9
M77.4
ICD-10 Finland
Metatarsalgia
2.1
7.4
73
367
M01AC06
ATC
meloxicam; systemic, rectal
1.4
7.4
392
3046
SPAT1104
SPAT
Monitoring of emergency patient
2.0
7.4
77
395
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.9
7.4
98
546
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.1
7.4
20
50
J01FA06
ATC
roxithromycin; oral
1.4
7.4
416
3269
A07AA09
ATC
vancomycin; oral
3.6
7.3
23
64
A29
ICPC
General symptom/complaint other
1.6
7.3
161
1036
K07.60
ICD-10 Finland
Snapping jaw
2.3
7.3
53
235
M01AH05
ATC
etoricoxib; oral
1.4
7.3
682
5842
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
9.4
7.3
14
15
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
3.5
7.3
24
69
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.0
7.3
80
418
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
2.3
7.3
54
242
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.5
7.2
45
186
R49.08
ICD-10 Finland
Other specified dysphonia
3.1
7.2
30
100
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
4.5
7.2
17
38
SBA10
NOMESCO Finland
Measurement of salivary flow rate
4.0
7.2
20
51
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.9
7.2
96
536
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
7.2
445
3551
P76
ICPC
Depressive disorder
2.1
7.1
69
344
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.7
7.1
37
140
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.1
770
6752
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.8
7.1
34
123
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.3
7.1
50
219
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.4
7.1
46
194
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
6.1
7.1
18
30
XKC03
NOMESCO Finland
Water cystometry
2.6
7.1
39
152
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.7
7.1
151
964
Y96.9
ICD-10 Finland
Unspecified type of accident
3.1
7.1
29
96
K29
ICPC
Cardiovascular sympt/complt other
2.3
7.1
54
245
G25.0
ICD-10 Finland
Essential tremor
2.6
7.1
40
158
R5130, ,
SPAT
10.1
7.0
13
13
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.4
7.0
46
195
S01XA18
ATC
ciclosporin; ophthalmic
7.0
7.0
16
23
H01
ICPC
Ear pain/earache
1.7
7.0
121
730
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
2.1
7.0
68
340
J01AA02
ATC
doxycycline; systemic
1.5
7.0
855
7651
SPAT1153
SPAT
Removal of sutures
1.4
7.0
353
2713
M01AX17
ATC
nimesulide; oral
1.5
7.0
261
1893
R25.2
ICD-10 Finland
Cramp and spasm
2.7
7.0
35
130
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
4.4
7.0
17
39
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
7.0
304
2273
B05DB
ATC
Hypertonic solutions
6.4
6.9
17
27
XG410
NOMESCO Finland
Flow-volume spirometry
2.2
6.9
54
248
J96.1
ICD-10 Finland
Chronic respiratory failure
2.8
6.8
33
120
L29.9
ICD-10 Finland
Pruritus, unspecified
2.6
6.8
37
143
SPAT1255
SPAT
Intravenous administration of medicine
1.9
6.8
80
428
J01MA06
ATC
norfloxacin; oral
1.7
6.8
133
830
Z00.0
ICD-10 Finland
General medical examination
1.5
6.8
214
1497
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.7
6.8
35
132
R20.0
ICD-10 Finland
Anaesthesia of skin
5.7
6.8
18
32
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.7
6.8
36
138
M01AH02
ATC
rofecoxib; oral
1.7
6.8
136
855
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
2.0
6.7
77
408
SBA00
NOMESCO Finland
Microbiological examinations
2.8
6.7
33
121
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.4
6.7
23
68
D02AX
ATC
Other emollients and protectives
2.7
6.7
34
127
S92.3
ICD-10 Finland
Fracture of metatarsal bone
2.4
6.7
45
193
J45
ICD-10 Finland
Asthma
1.8
6.7
109
646
C03DA01
ATC
spironolactone; oral
1.6
6.7
144
921
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
2.8
6.6
33
122
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
7.9
6.6
14
18
A03CA02
ATC
clidinium and psycholeptics; oral
2.1
6.6
63
313
R4190
NOMESCO Finland
Nutritional therapy
2.2
6.6
51
233
SPAT1360
SPAT
Extensive global examination
2.0
6.6
73
383
HA1AA
NOMESCO Finland
X-ray mammography
1.9
6.5
80
434
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.8
6.5
96
552
A10AC01
ATC
insulin (human); parenteral
1.9
6.5
86
478
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.8
6.5
93
530
M60.9
ICD-10 Finland
Myositis, unspecified
6.9
6.5
15
22
EBA00
NOMESCO Finland
Extraction of tooth
1.4
6.5
391
3091
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
6.5
93
531
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.2
6.5
16
26
B05DA
ATC
Isotonic solutions
5.4
6.5
18
34
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
5.4
6.5
18
34
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
2.7
6.4
33
124
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.4
6.4
42
178
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.8
6.4
31
113
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
2.5
6.4
39
160
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.3
6.4
47
210
M02AA10
ATC
ketoprofen; topical
1.6
6.4
172
1161
F60.9
ICD-10 Finland
Personality disorder, unspecified
4.1
6.4
17
42
H3603, E103,
ICD-10 Finland
6.6
6.3
15
23
NJ3BG
NOMESCO Finland
MRI examination of extremities with high intensity magnet
8.2
6.3
13
16
NF3AA
NOMESCO Finland
Femur X-ray examination
2.8
6.3
31
114
M54.8
ICD-10 Finland
Other dorsalgia
2.2
6.3
52
244
B01AB10
ATC
tinzaparin; parenteral
1.7
6.3
125
783
N17.8
ICD-10 Finland
Other acute renal failure
3.4
6.3
22
66
OAB43, ,
SPAT
0.6
6.3
120
1854
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.4
6.3
41
174
M35.3
ICD-10 Finland
Polymyalgia rheumatica
2.1
6.3
54
258
K11.2
ICD-10 Finland
Sialoadenitis
2.4
6.3
40
168
S00.0
ICD-10 Finland
Superficial injury of scalp
2.6
6.2
35
138
TKC22
NOMESCO Finland
Catheterisation instruction
2.6
6.2
35
138
U05
ICPC
Urination problems other
2.0
6.2
69
362
R31
ICD-10 Finland
Unspecified haematuria
1.6
6.2
131
833
M15.8
ICD-10 Finland
Other polyarthrosis
2.7
6.2
31
115
RS221, ,
NOMESCO Finland
3.7
6.2
19
52
Z46.9
ICD-10 Finland
Fitting and adjustment of unspecified device
3.7
6.2
19
52
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.3
6.2
44
194
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
3.2
6.2
24
77
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
2.9
6.2
27
93
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
2.9
6.2
27
93
R07.0
ICD-10 Finland
Pain in throat
2.0
6.2
67
349
M01AB05
ATC
diclofenac; systemic, rectal
1.4
6.2
712
6232
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
6.2
152
1005
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
6.2
72
385
ZYC01
NOMESCO Finland
Remote contact by phone
1.9
6.2
72
385
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
6.1
278
2087
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.0
6.1
67
350
N07BC02
ATC
methadone; systemic
7.7
6.1
13
17
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
6.1
157
1048
S20
ICPC
Corn/callosity
2.7
6.1
31
116
L04AA01
ATC
[U] ciclosporin
3.8
6.1
18
48
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
3.8
6.1
18
48
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.1
6.1
25
83
R26.0
ICD-10 Finland
Ataxic gait
12.6
6.1
10
8
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.9
6.1
76
416
C08CA01
ATC
amlodipine; oral
1.4
6.1
444
3617
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.1
6.1
53
255
R68.2
ICD-10 Finland
Dry mouth, unspecified
6.7
6.0
14
21
A03
ICPC
Fever
1.6
6.0
167
1134
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
5.2
6.0
17
33
WX730
NOMESCO Finland
Conventional respirator
3.3
6.0
22
68
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
3.4
6.0
21
63
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.7
6.0
123
777

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
494
784
10.25
307.65
2.4
2.6
—
—
—
0
0
523
971
9.00
299.61
2.6
2.9
67.39
66.21
g/l
2.91
486
892
351
674
7.04
186.16
2.7
2.5
24.11
19.57
au/ml
0.31
26
57
294
471
8.03
184.84
2.6
2.3
7.05
7.32
g/l
1.63
269
430
294
471
8.03
184.84
2.6
2.3
3.68
3.76
g/l
0.28
269
430
294
471
8.03
184.84
2.6
2.3
4.21
4.17
g/l
0.26
269
430
334
616
7.22
184.11
1.4
1.3
29.34
50.82
au/ml
—
7
52
279
442
8.00
176.74
2.7
2.3
2.69
3.01
g/l
5.22
254
401
260
411
7.87
164.41
2.6
2.4
9.31
10.66
g/l
4.54
233
367
476
1399
5.08
154.45
1.6
1.3
444.27
514.53
titre
0.44
103
300
232
401
6.99
133.67
1.4
1.2
—
—
—
0
0
243
480
6.14
121.87
1.5
1.4
12.23
10.50
iu/ml
—
7
13
724
3438
3.95
113.20
3.6
2.2
175.09
215.92
u/l
0.85
698
3265
68
20
36.06
107.88
1.4
1.1
135.08
66.66
nmol/l
2.06
48
12
878
4867
4.33
106.64
8.2
5.3
35.64
35.36
g/l
0.75
837
4581
93
66
15.24
103.36
1.2
1.1
42.95
40.60
mg/l
0.14
82
58
873
4883
4.21
103.07
2.9
2.2
97.77
95.06
pmol/l
0.91
521
2662
91
64
15.35
101.62
1.1
1.1
309.59
257.75
mg/l
1.21
86
56
83
52
17.12
98.44
1.2
1.1
0.53
0.52
ratio
0.17
52
32
80
52
16.45
93.06
1.1
1.2
140.99
149.20
nmol/l
0.38
80
52
193
413
5.41
87.36
1.7
1.9
10.21
8.64
iu/ml
0.14
67
96
144
237
6.80
85.65
1.3
1.4
5.46
48.95
e6/l
0.91
112
168
903
5520
3.90
85.22
13.8
7.6
1.21
1.21
mmol/l
0.73
817
4761
144
241
6.68
84.24
1.4
1.4
58.44
591.57
e6/l
0.56
120
181
282
859
4.02
81.32
3.6
2.8
10.28
10.88
g/l
1.37
261
795
178
386
5.27
79.05
1.3
1.2
1.76
1.25
u/ml
0.13
16
25
140
249
6.26
76.93
1.7
1.6
—
—
—
0
0
148
288
5.75
73.96
1.3
1.2
46.74
3.04
u/ml
—
10
10
822
4987
3.24
72.99
12.9
7.0
1.21
1.21
mmol/l
0.14
774
4612
623
3261
2.97
72.02
2.1
1.7
21.19
20.21
nmol/l
0.80
550
2762
458
2046
3.05
70.37
2.1
1.5
2.40
2.57
g/l
0.83
302
1237
860
5421
3.28
70.09
10.8
6.3
0.04
0.04
e9/l
0.74
771
4609
865
5491
3.28
69.22
10.9
6.3
1.81
1.94
e9/l
1.34
782
4810
856
5407
3.24
68.97
10.8
6.3
0.59
0.60
e9/l
0.48
766
4593
872
5581
3.28
68.37
11.4
6.5
0.20
0.19
e9/l
0.19
786
4849
914
6020
3.47
68.08
14.9
9.8
4.05
4.18
e9/l
1.09
827
5208
120
211
6.23
66.49
1.2
1.2
45.55
55.34
u/ml
0.17
12
20
437
1955
2.99
66.24
5.7
3.4
0.82
0.82
mmol/l
0.38
409
1854
478
2268
2.89
64.68
1.6
1.3
0.98
1.53
u/ml
1.06
110
619
414
1834
2.96
63.42
1.9
1.7
1173.33
1179.13
nmol/l
0.04
328
1379
119
219
5.94
62.85
1.3
1.3
—
—
—
0
0
69
9
81.57
61.76
1.1
1.1
—
—
—
0
0
145
334
4.82
59.41
2.2
1.5
1.13
1.21
g/l
2.39
140
317
408
1863
2.84
58.23
1.5
1.3
31.63
33.37
iu/ml
0.08
118
573
128
273
5.15
57.39
1.3
1.2
1.98
2.47
u/ml
—
9
26
128
274
5.13
57.14
1.4
1.2
4.34
9.31
u/ml
0.49
18
40
636
3669
2.63
56.27
10.8
6.2
—
—
—
0
0
596
3338
2.62
56.00
7.2
4.3
7.39
7.40
ph
0.72
440
2410
851
5758
2.81
52.85
9.8
7.0
11.37
12.06
umol/l
0.49
823
5512
347
1522
2.83
52.67
1.8
1.8
—
—
—
0
0
773
4993
2.65
52.66
11.5
6.5
9.13
9.04
%
0.36
752
4694
772
4989
2.65
52.44
11.3
6.4
2.98
2.86
%
0.74
751
4692
770
4984
2.63
51.89
11.0
6.3
57.65
57.59
%
0.04
752
4773
737
4682
2.58
51.50
3.4
2.4
77.95
77.26
nmol/l
0.26
679
4186
528
2880
2.53
51.17
2.9
2.3
2.65
2.89
mg/l
1.73
457
2489
768
4991
2.60
50.87
11.6
6.5
0.70
0.68
%
0.52
746
4686
777
5078
2.61
50.85
11.2
6.5
26.75
27.09
%
0.37
759
4826
352
1585
2.75
50.51
11.6
6.0
1.07
1.03
mmol/l
1.73
334
1468
736
4718
2.54
49.70
4.6
3.1
157.92
142.54
ug/l
0.98
685
4392
56
59
9.92
48.05
1.6
1.5
5.42
6.20
u/l
0.36
50
46
302
1289
2.82
47.71
2.6
1.7
—
—
—
0
0
619
3718
2.43
47.47
4.5
3.6
2.34
2.35
mmol/l
0.89
568
3371
558
3207
2.43
47.17
7.1
4.4
—
—
—
0
0
1039
8048
3.85
46.87
15.2
8.6
80.27
80.68
u/l
0.10
1016
7648
156
456
3.80
46.24
3.1
2.2
671.92
491.05
ug/l
0.28
151
438
148
418
3.91
46.07
4.0
3.8
224.51
67.99
mg/l
0.40
135
361
388
1908
2.56
45.88
4.4
2.6
12.97
12.90
umol/l
0.07
361
1774
147
417
3.89
45.46
4.1
3.8
26.41
54.31
mg/l
2.27
135
362
256
1034
2.90
44.56
3.0
2.2
329.14
381.66
nmol/l
3.55
241
968
138
380
3.99
44.47
4.1
3.5
76.98
3.65
ratio
0.51
92
220
367
1788
2.54
43.96
4.4
2.6
2.26
2.28
g/l
0.34
341
1654
687
4422
2.36
43.61
5.1
3.4
6.45
6.21
ph
5.86
369
2458
262
1084
2.83
43.50
1.8
1.6
—
—
—
0
0
197
698
3.20
43.10
3.0
1.8
1.66
1.38
g/l
0.70
182
644
598
3644
2.33
42.94
5.6
3.4
33.61
95.04
e6/l
1.83
488
2806
272
1163
2.75
42.29
6.4
3.7
2.03
1.85
mmol/l
0.36
244
1001
644
4086
2.30
41.53
6.6
4.0
58.43
113.19
e6/l
1.39
499
2925
802
5587
2.42
41.45
6.1
3.9
0.05
0.28
estimate
0.41
139
1114
799
5568
2.41
41.09
6.0
3.9
10.68
3.04
estimate
0.32
149
1196
275
1214
2.66
39.91
6.7
3.7
7.37
7.38
ph
1.58
189
686
911
6779
2.62
39.81
8.1
4.6
172.33
1820.66
e6/l
—
9
100
340
1663
2.48
39.80
4.6
2.7
22.53
22.91
%
0.22
319
1554
787
5496
2.35
39.52
6.1
3.9
0.00
0.00
estimate
0.50
149
1181
271
1204
2.63
38.71
6.5
3.7
5.89
5.83
kpa
0.47
265
1168
871
6408
2.45
37.97
9.9
5.4
6.78
6.74
mmol/l
0.18
852
6125
240
1014
2.72
37.82
5.0
3.1
4.62
4.48
kpa
0.49
234
982
558
3449
2.19
36.94
4.7
2.6
57.23
84.36
u/l
0.61
522
3201
522
3156
2.19
36.39
5.3
3.3
0.34
0.44
e6/l
0.74
417
2331
326
1621
2.41
36.34
3.0
2.1
—
—
—
0
0
247
1080
2.64
36.22
14.5
7.6
10.72
10.22
mmol/l
0.50
237
1041
422
2351
2.25
35.97
2.4
1.8
1.44
1.31
mg/l
0.18
348
1837
516
3130
2.17
35.41
4.4
3.1
—
—
—
0
0
370
1964
2.30
35.32
4.5
3.0
0.91
0.99
e6/l
0.24
226
1060
348
1802
2.33
35.19
3.6
2.2
29.24
29.57
s
0.50
338
1756
289
1385
2.45
34.78
3.1
2.6
1.83
1.81
%
0.13
255
1247
337
1738
2.32
34.27
1.5
1.3
5.96
12.61
u/ml
1.41
129
644
66
124
5.58
33.84
2.0
2.4
—
—
—
0
0
38
38
10.31
33.74
1.1
1.1
31.00
413.22
ng/l
—
12
9
739
5222
2.15
33.23
20.1
16.2
1.26
1.27
inr
0.34
629
4354
62
115
5.64
32.22
1.4
1.5
—
—
—
0
0
433
2527
2.14
32.06
4.2
2.7
5.07
5.25
e6/l
0.09
410
2315
241
1103
2.50
31.77
9.4
8.5
1.29
1.36
mmol/l
0.44
236
1082
237
1079
2.50
31.59
2.8
2.8
68.15
70.35
e9/l
0.40
167
813
549
3544
2.04
30.62
3.8
3.3
1591.97
1315.05
ng/l
0.79
485
3061
40
49
8.42
30.50
1.4
1.8
30.84
30.18
umol/l
0.09
40
44
429
2546
2.09
29.95
6.0
3.7
0.50
0.17
—
6
30
960
7678
2.47
29.90
5.6
4.2
14.79
14.88
pmol/l
0.60
887
7012
50
81
6.41
29.80
1.1
1.1
1.92
4.01
nmol/l
—
9
12
879
6801
2.22
29.21
5.0
3.5
57.34
53.41
u/l
0.51
835
6395
61
123
5.18
28.92
1.3
1.4
—
—
—
0
0
184
775
2.63
28.64
1.3
1.2
—
—
—
0
0
147
552
2.91
28.52
2.7
1.9
1.53
1.54
g/l
0.05
123
490
194
844
2.56
28.24
6.4
4.0
106.15
91.17
ng/l
0.98
174
734
224
1044
2.42
28.11
12.3
9.8
—
—
—
0
0
542
3572
1.97
27.62
4.7
3.4
31.54
33.66
u/l
0.90
516
3377
58
117
5.17
27.48
1.5
1.2
—
—
—
0
0
373
2157
2.08
27.46
4.2
3.0
509.28
541.87
mosm/kgh2o
2.20
346
1899
233
1119
2.36
27.26
3.0
2.4
0.22
0.21
g/l
1.37
222
1044
449
2783
2.00
27.21
7.5
4.4
88.71
87.31
%
0.56
442
2730
494
3178
1.97
26.78
11.0
6.4
—
—
—
0
0
42
64
6.77
26.51
4.0
2.3
545.86
633.23
e6/l
0.23
36
53
130
475
2.96
26.44
1.8
1.7
0.38
0.36
mg/l
0.15
65
230
254
1285
2.25
26.19
1.8
1.6
—
—
—
0
0
50
92
5.64
26.19
3.9
2.1
1315.36
1324.61
e6/l
0.02
45
82
459
2917
1.95
25.47
4.0
2.9
345.48
352.61
umol/l
0.74
410
2566
269
1408
2.19
25.43
12.4
8.5
7.41
7.42
ph
0.37
156
769
56
120
4.85
24.74
1.3
1.1
—
—
—
0
0
322
1822
2.06
24.74
4.8
3.2
2.51
2.13
e6/l
0.28
183
913
36
50
7.40
24.69
1.2
1.0
2011.03
1614.06
miu/ml
0.88
36
50
370
2208
1.99
24.46
3.2
3.1
2.45
2.45
mmol/l
0.18
342
1989
264
1396
2.15
24.19
12.4
8.5
1.11
0.86
mmol/l
0.39
224
1159
600
4228
1.87
23.72
5.3
3.9
33.61
64.81
ng/l
1.34
469
3184
521
3511
1.88
23.72
3.9
2.5
—
—
—
0
0
371
2244
1.96
23.40
1.9
1.8
10256874.44
26350321.84
pmol/l
0.56
312
1852
277
1511
2.10
23.31
1.4
1.2
—
—
—
0
0
111
401
2.96
22.97
3.4
3.9
390.00
289.87
mg/l
0.47
57
184
263
1415
2.11
22.91
12.6
8.5
5.13
5.11
kpa
0.12
257
1361
164
724
2.47
22.90
1.7
1.5
—
—
—
0
0
254
1356
2.12
22.54
2.1
1.4
—
—
—
0
0
262
1416
2.10
22.51
12.6
8.4
11.67
12.07
kpa
0.80
257
1366
1110
9893
4.00
22.13
37.5
17.2
24.47
25.80
mg/l
0.69
1018
8232
242
1280
2.13
21.95
13.1
8.8
95.32
95.60
%
0.26
235
1240
49
105
4.83
21.65
1.1
1.2
—
—
—
0
0
1059
9219
2.76
21.56
7.4
5.2
1.93
1.95
mu/l
0.14
1006
8474
667
4949
1.82
21.45
4.0
2.9
—
—
estimate
—
0
0
641
4701
1.82
21.42
18.6
11.8
0.00
0.00
e9/l
0.03
538
3829
373
2316
1.90
21.40
7.0
4.9
—
—
—
0
0
238
1270
2.10
21.01
3.9
2.9
8.73
8.07
umol/l
0.13
202
1132
415
2681
1.85
20.93
3.7
2.5
—
—
—
0
0
35
58
6.19
20.38
1.5
1.7
—
—
—
0
0
54
133
4.21
20.07
2.1
2.6
0.71
1.35
g/24h
0.77
28
80
461
3108
1.80
20.01
6.4
4.0
0.00
0.01
estimate
1.15
132
1083
435
2888
1.81
19.83
4.3
2.9
0.00
0.03
0.49
12
64
204
1051
2.14
19.64
3.8
2.5
36.88
40.14
u/l
0.27
176
880
144
652
2.38
18.88
4.5
2.8
1.28
1.19
%
0.53
144
647
27
13
21.23
18.66
1.0
1.0
—
—
—
0
0
122
520
2.50
18.23
2.6
1.8
1.11
1.99
ug/l
0.69
109
469
345
2187
1.82
17.98
6.2
4.1
156.89
379.11
ng/l
2.87
299
1779
194
1016
2.09
17.78
2.4
2.1
0.00
0.01
estimate
0.50
34
208
62
185
3.48
17.58
1.7
1.6
0.66
0.81
g/l
0.53
53
149
559
4087
1.71
17.55
2.5
2.2
—
—
—
0
0
32
57
5.75
17.33
1.1
1.1
—
—
—
0
0
558
4127
1.68
16.40
6.3
3.9
0.02
0.03
estimate
0.17
130
981
368
2433
1.75
16.35
6.4
4.0
1.02
1.02
kg/l
0.31
264
1637
24
13
18.82
16.04
1.0
1.0
8.33
7.57
mg/g
0.21
24
13
219
1240
1.95
16.02
12.1
7.5
—
—
—
0
0
182
966
2.05
15.99
1.4
1.4
—
—
—
0
0
186
1002
2.02
15.67
5.9
4.6
0.98
0.88
%
0.23
70
331
31
59
5.37
15.66
2.2
2.8
861.16
1360.34
u/ml
0.50
31
59
84
321
2.74
15.62
1.6
1.5
286.71
273.00
ug/g
0.20
48
202
217
1236
1.93
15.56
2.9
2.4
89.37
131.68
ug/g
2.37
177
985
150
751
2.15
15.35
11.3
10.8
24.24
24.29
mmol/l
0.07
145
740
43
110
4.02
15.22
1.7
1.3
—
—
—
0
0
157
804
2.10
15.15
5.1
4.1
7.41
7.42
ph
1.31
140
677
43
111
3.98
15.04
1.7
1.3
2.75
2.89
g/l
0.18
34
83
43
111
3.98
15.04
1.7
1.3
5.94
7.22
g/l
1.48
33
83
43
111
3.98
15.04
1.7
1.3
0.40
0.43
g/l
0.14
34
83
160
828
2.08
15.01
5.2
4.0
5.24
5.14
kpa
0.80
154
803
63
212
3.09
14.74
1.7
1.4
—
—
—
0
0
1113
10259
3.23
14.44
41.6
20.7
139.28
139.68
mmol/l
5.49
1105
10079
42
110
3.92
14.41
1.1
1.4
—
—
—
0
0
59
194
3.15
14.35
1.7
1.5
128.94
160.13
au/ml
0.83
20
58
1113
10274
3.19
14.10
42.0
20.9
4.01
3.99
mmol/l
1.89
1101
10080
53
165
3.32
14.09
9.8
6.5
12.06
12.04
mg/l
0.01
48
152
178
979
1.97
14.06
2.8
2.4
9.80
7.52
ug/l
0.29
147
883
121
580
2.21
13.78
2.9
3.7
4.31
4.52
pmol/l
1.65
106
518
63
221
2.96
13.72
1.5
1.3
51.89
61.70
mmol/l
1.35
53
187
1073
9757
2.37
13.58
6.7
5.4
6.08
6.02
mmol/l
0.63
999
8919
172
948
1.96
13.48
6.1
4.7
0.09
0.13
%
0.43
56
280
24
42
5.81
13.24
1.5
1.7
41.56
40.25
g/l
0.51
24
42
171
955
1.93
12.86
6.1
5.0
0.17
0.14
%
0.10
48
254
170
953
1.92
12.63
5.8
4.5
0.62
0.65
%
0.07
61
306
111
532
2.20
12.63
2.5
2.2
0.00
1.51
estimate
0.50
24
166
39
107
3.74
12.56
2.3
2.8
1222.79
1006.79
mg
0.26
39
107
177
1010
1.89
12.45
6.3
4.4
7.36
7.35
ph
0.16
141
733
33
81
4.16
12.36
3.4
3.0
42.94
39.27
%
0.48
18
43
1053
9575
2.11
12.13
8.8
6.8
40.38
39.70
mmol/mol
1.31
999
8944
55
192
2.96
12.10
1.9
1.8
—
—
—
0
0
70
278
2.62
12.09
5.6
3.2
33.92
33.44
umol/l
0.06
65
245
123
630
2.07
11.79
1.6
1.6
—
—
—
0
0
1119
10467
3.10
11.72
22.5
12.7
25.81
26.57
u/l
1.07
1099
10187
22
22
10.17
11.52
3.2
2.0
0.13
0.52
e9/l
—
17
6
108
531
2.14
11.52
2.5
2.3
—
—
—
0
0
41
124
3.39
11.44
1.4
1.5
32.62
34.25
ng/l
0.04
41
124
199
1214
1.77
11.21
3.7
4.4
148.69
22.56
ug/l
0.42
164
1003
57
212
2.78
11.19
1.4
1.2
242.01
268.70
u/ml
0.27
37
124
511
3941
1.53
11.10
4.1
3.5
7.00
7.77
mmol/l
3.59
444
3318
112
569
2.07
10.96
5.4
4.3
—
—
—
0
0
215
1349
1.73
10.96
3.0
3.4
5.89
5.23
e9/l
0.15
177
1171
490
3773
1.52
10.56
3.9
3.6
85.67
51.18
mg/l
1.42
336
2494
70
300
2.42
10.33
2.0
1.9
172.28
206.87
pmol/l
1.89
64
282
31
84
3.76
10.19
1.1
1.1
—
—
—
0
0
848
7361
1.57
10.16
5.4
4.4
0.33
5317.00
—
6
19
56
222
2.60
9.74
1.3
1.2
—
—
—
0
0
29
78
3.79
9.64
1.1
1.1
—
—
—
0
0
67
292
2.37
9.54
1.2
1.1
—
—
—
0
0
15
10
15.17
9.52
1.1
1.4
67.47
65.20
ug/l
—
15
10
488
3834
1.47
9.13
4.6
4.3
15.70
8.76
mg/mmol
1.98
329
2456
90
453
2.07
9.04
5.7
4.5
24.97
24.85
mmol/l
0.15
84
425
69
313
2.28
8.98
1.4
1.3
—
—
—
0
0
1086
10189
2.07
8.35
28.9
15.5
—
—
—
0
0
102
554
1.92
8.28
11.0
4.5
36.91
36.91
°c
0.02
102
549
32
102
3.20
8.27
1.2
1.2
—
—
—
0
0
169
1073
1.67
8.12
3.0
2.4
13.07
13.36
nmol/l
0.16
150
953
61
275
2.29
8.08
3.6
3.0
1.47
1.57
mmol/l
0.51
61
270
46
182
2.59
8.07
3.0
2.2
7.29
3452.25
u/l
0.97
16
66
36
125
2.94
8.07
1.4
1.3
0.18
0.19
nmol/l
0.25
31
100
191
1260
1.62
7.88
1.4
1.4
—
—
—
0
0
117
676
1.81
7.83
1.6
1.3
218.62
259.61
u/ml
0.28
109
623
91
485
1.95
7.81
1.3
1.2
—
—
—
0
0
24
66
3.69
7.76
2.3
1.8
—
—
—
0
0
37
134
2.82
7.70
1.3
1.3
—
—
—
0
0
41
157
2.67
7.68
2.0
1.6
—
—
—
0
0
41
157
2.67
7.68
2.0
1.6
—
—
—
0
0
41
157
2.67
7.68
2.0
1.6
—
—
—
0
0
41
157
2.67
7.68
2.0
1.6
—
—
—
0
0
27
82
3.35
7.55
1.2
1.1
—
—
—
0
0
42
167
2.57
7.32
1.4
1.1
50.45
90.69
iu/ml
0.35
13
35
66
321
2.12
7.28
1.1
1.1
—
—
—
0
0
95
527
1.87
7.24
1.5
1.2
—
—
—
0
0
45
186
2.48
7.24
1.1
1.0
—
—
—
0
0
82
437
1.94
7.06
3.7
2.8
24.74
24.87
mmol/l
0.10
82
431
62
299
2.13
7.00
4.3
3.5
1.68
1.89
index
0.13
37
167
17
39
4.41
6.97
1.4
1.6
—
—
—
0
0
58
274
2.18
6.90
1.5
1.4
11.95
9.19
u/l
0.50
42
217
32
114
2.86
6.88
6.2
4.7
—
—
—
0
0
1122
10742
2.47
6.86
52.2
26.0
91.77
91.34
fl
2.32
1117
10634
1122
10742
2.47
6.86
52.4
26.1
247.26
244.79
e9/l
0.62
1110
10545
1122
10744
2.46
6.82
52.4
26.1
4.35
4.50
e12/l
15.77
1104
10511
1122
10745
2.46
6.80
52.4
26.1
6.84
6.79
e9/l
0.42
1107
10508
31
110
2.87
6.72
2.5
2.3
—
—
—
0
0
65
327
2.05
6.59
4.0
3.8
8.55
8.14
kpa
1.25
65
321
38
153
2.53
6.48
1.7
1.2
4.80
6.41
u/ml
0.27
20
73
209
1469
1.52
6.47
1.5
1.3
—
—
—
0
0
33
124
2.71
6.45
1.3
1.3
—
—
nmol/l
—
0
0
19
51
3.77
6.38
1.2
1.4
137.11
182.39
mmol/24h
0.98
19
51
54
259
2.14
6.21
4.2
3.8
—
—
—
0
0
18
36
5.06
6.19
4.1
2.6
0.61
0.60
mmol/l
0.22
18
36
40
169
2.42
6.18
4.9
4.2
0.84
1.50
%
0.92
35
155
28
99
2.87
6.13
1.6
1.4
41.62
27.25
u/l
1.00
22
83
32
122
2.67
6.10
2.3
1.6
—
—
—
0
0
24
78
3.12
6.06
1.1
1.2
349.06
396.18
nmol/l
0.43
18
67
127
808
1.64
6.03
3.9
2.5
6.16
6.07
ph
0.49
76
547
42
185
2.32
5.93
1.1
1.1
—
—
—
0
0
1065
10075
1.72
5.87
7.2
6.1
2.60
2.64
mmol/l
0.78
995
9324
30
113
2.70
5.86
5.4
4.5
60.76
53.46
%
0.87
25
100
33
131
2.56
5.82
1.3
1.4
275.33
277.79
mosm/kgh2o
0.27
24
101
57
290
2.02
5.64
1.8
1.6
12081.20
16496.57
e6/l
0.51
50
206
1051
9927
1.64
5.59
6.3
5.4
4.49
4.54
mmol/l
0.75
981
9227
16
32
5.05
5.57
1.3
1.5
—
—
—
0
0
87
516
1.74
5.37
4.4
3.4
1.02
1.02
ratio
0.62
82
476
364
2920
1.36
5.33
5.1
3.4
0.00
0.04
estimate
0.77
115
920
41
188
2.22
5.30
2.6
1.9
5.41
4.81
mmol/24h
0.43
36
168
135
901
1.56
5.26
4.0
3.1
195.70
203.29
ng/l
0.07
121
829
1007
9446
1.51
5.22
5.6
4.5
1.38
1.31
mmol/l
2.37
928
8640
28
109
2.61
5.16
1.4
1.1
—
—
—
0
0
84
501
1.73
5.09
2.2
2.7
—
—
—
0
0
39
787
0.48
5.08
1.7
1.4
—
—
—
0
0
10
12
8.39
5.06
1.1
1.2
83.80
45.80
%
—
5
5
9
9
10.07
5.03
2.4
4.1
—
—
—
0
0
1043
9874
1.57
5.00
6.1
5.3
1.42
1.43
mmol/l
0.28
970
9107
79
467
1.74
4.95
2.8
1.9
—
—
—
0
0
51
263
1.98
4.89
3.6
2.8
90.99
89.75
%
0.77
51
254
21
73
2.91
4.78
4.2
1.7
161.98
99.32
ng/l
0.90
21
73
16
47
3.44
4.75
2.3
1.8
60.01
53.65
ug/l
0.26
16
47
15
43
3.52
4.62
1.7
1.9
2.17
1.81
umol/l
1.32
15
36
16
48
3.37
4.61
1.4
1.2
—
—
—
0
0
9
11
8.24
4.56
1.3
1.3
—
—
—
0
0
518
4449
1.30
4.51
5.9
5.6
1.90
2.65
ug/l
1.65
466
4018
13
27
4.86
4.50
3.1
1.5
—
—
—
0
0
27
112
2.44
4.41
1.1
1.2
—
—
—
0
0
97
626
1.60
4.38
1.4
1.2
148.85
138.82
u/ml
0.10
33
242
13
28
4.68
4.37
1.2
1.1
—
—
—
0
0
105
695
1.56
4.27
1.3
1.3
—
—
—
0
0
52
284
1.87
4.25
2.4
2.3
136.18
131.27
g/l
0.70
38
227
13
29
4.52
4.25
1.0
1.0
—
—
—
0
0
48
256
1.91
4.22
2.1
3.6
155.71
1549.52
u/ml
0.80
43
241
14
34
4.16
4.21
4.3
4.4
—
—
—
0
0
47
249
1.93
4.21
4.4
4.4
—
—
—
0
0
17
57
3.01
4.13
3.9
2.5
—
—
—
0
0
13
30
4.37
4.13
1.5
1.7
78.31
95.93
nmol/24h
0.29
13
30
60
350
1.75
3.98
1.6
1.4
28.83
26.90
iu/l
0.16
52
295
27
118
2.32
3.96
1.7
1.6
71.44
61.16
%
0.64
18
77
35
171
2.08
3.93
3.5
2.4
—
—
—
0
0
27
120
2.28
3.82
1.1
1.1
2.25
2.33
eliau/ml
0.02
11
47
10
20
5.03
3.69
1.1
1.1
—
—
—
0
0
318
3805
0.77
3.68
3.6
3.3
—
—
—
0
0
13
35
3.74
3.59
2.8
1.5
32.38
31.49
%
0.07
13
35
40
213
1.91
3.57
2.4
1.5
—
—
—
0
0
25
111
2.28
3.56
1.4
1.5
0.17
0.32
nmol/l
1.40
18
81
7
9
7.82
3.56
1.0
1.0
—
—
—
0
0
10
21
4.79
3.56
1.4
1.2
—
—
—
0
0
6
6
10.04
3.50
1.7
1.0
—
—
—
0
0
6
6
10.04
3.50
1.0
1.3
—
—
—
0
0
16
58
2.78
3.43
2.2
1.5
—
—
—
0
0
11
27
4.10
3.40
3.0
2.4
—
—
—
0
0
8
14
5.75
3.34
1.3
1.3
—
—
—
0
0
58
354
1.67
3.32
1.6
1.6
20.52
13.25
u/ml
—
8
75
28
135
2.10
3.30
1.5
1.3
303.32
351.90
pmol/l
0.33
22
119
45
257
1.78
3.26
1.2
1.1
—
—
—
0
0
8
15
5.36
3.19
14.3
7.9
8.60
5.71
mmol/l
—
8
15
12
316
0.37
3.12
1.1
1.2
1.62
1.51
g/l
0.66
12
316
145
1089
1.38
3.12
1.6
1.6
—
—
—
0
0
23
105
2.21
3.10
1.3
1.2
—
—
—
0
0
19
80
2.40
3.07
1.1
1.1
36.11
36.45
mmol/l
0.01
19
75
17
68
2.52
3.05
1.3
1.4
1.55
1.10
nmol/l
0.40
12
50
20
88
2.30
2.94
2.0
1.4
20.90
32.02
%
0.76
13
58
10
27
3.73
2.88
1.6
1.6
—
—
—
0
0
499
4427
1.22
2.87
2.1
2.0
1.45
1.36
mmol/l
1.53
432
3696
28
143
1.98
2.86
1.3
1.2
—
—
—
0
0
19
83
2.31
2.85
1.6
1.9
0.71
1.93
u/field
—
7
42
26
131
2.01
2.77
1.3
1.1
—
—
—
0
0
42
248
1.72
2.75
1.5
1.9
2.83
28.05
iu/l
0.54
13
98
7
14
5.02
2.73
1.0
1.1
—
—
—
0
0
13
48
2.73
2.72
1.2
1.1
627.23
237.74
iu/ml
0.57
13
48
22
105
2.12
2.70
4.5
3.6
18.06
11.45
index
1.34
16
67
10
29
3.47
2.69
1.4
1.4
27.90
29.38
s
—
10
29
12
43
2.81
2.65
3.0
2.7
—
—
—
0
0
11
35
3.16
2.64
1.1
1.1
—
—
—
0
0
11
35
3.16
2.64
1.1
1.1
—
—
—
0
0
11
35
3.16
2.64
1.1
1.1
—
—
—
0
0
16
67
2.41
2.64
3.9
4.0
0.56
0.88
index
1.38
16
67
16
68
2.37
2.56
1.4
1.4
70.75
82.12
umol/l
1.20
16
68
332
2857
1.23
2.51
1.4
1.4
—
—
—
0
0
44
273
1.64
2.43
2.3
2.5
81.83
111.39
ug/min
0.30
25
165
38
227
1.70
2.42
5.0
4.5
2.94
2.49
mmol/l
0.39
29
158
11
38
2.91
2.41
3.2
3.0
—
—
—
0
0
29
160
1.83
2.41
4.0
2.6
—
—
—
0
0
14
58
2.43
2.37
1.1
1.3
—
—
—
0
0
5
8
6.27
2.37
1.0
1.3
84.00
79.87
umol/l
—
5
8
8
22
3.65
2.36
2.3
3.7
—
—
—
0
0
7
17
4.14
2.36
2.7
4.1
—
—
—
0
0
67
462
1.48
2.35
2.4
3.7
20.19
3269.20
u/ml
0.88
57
399
14
59
2.39
2.29
1.0
1.1
17.10
6.82
iu/ml
—
5
20
33
193
1.73
2.28
11.6
1.8
—
—
—
0
0
40
250
1.62
2.18
3.1
2.7
16.82
16.42
%
0.36
40
243
18
87
2.09
2.17
2.9
1.1
91.50
104.72
pmol/l
0.47
18
87
9
30
3.02
2.15
1.1
1.5
9.63
7.64
mmol/l
—
9
30
10
36
2.79
2.14
1.1
1.0
—
—
—
0
0
11
43
2.57
2.08
1.5
2.0
2.65
5.65
nmol/l
0.31
11
38
41
264
1.57
2.00
2.4
1.5
—
—
—
0
0
7
21
3.35
1.96
1.7
1.4
—
—
—
0
0
37
234
1.60
1.95
3.9
3.1
56.82
58.36
%
0.32
37
234
8
27
2.98
1.94
1.1
1.2
—
—
—
0
0
24
136
1.78
1.88
1.2
1.2
—
—
—
0
0
17
86
1.99
1.85
1.6
1.5
1.27
0.96
promille
0.29
11
71
13
59
2.22
1.84
1.3
1.3
5.45
6.34
ug/l
0.33
13
51
112
882
1.30
1.82
6.4
4.1
1.22
1.22
mmol/l
0.09
102
768
15
73
2.07
1.81
1.1
1.3
7.39
7.37
ph
—
9
51
26
154
1.70
1.77
1.8
1.5
1807.28
1775.73
e6/l
0.02
18
109
14
67
2.10
1.76
1.4
1.3
138.06
156.49
pmol/l
0.24
14
67
19
104
1.84
1.68
1.7
1.3
8064.62
135539.24
e6/l
1.19
13
72
41
278
1.49
1.63
2.4
1.5
—
—
—
0
0
41
278
1.49
1.63
2.4
1.5
—
—
—
0
0
41
279
1.49
1.61
2.4
1.5
—
—
—
0
0
41
279
1.49
1.61
2.4
1.5
—
—
—
0
0
7
26
2.70
1.58
2.3
2.0
—
—
—
0
0
5
15
3.34
1.52
1.6
2.2
10.30
15.77
umol/l
—
5
15
6
21
2.87
1.50
1.0
1.1
—
—
—
0
0
22
131
1.69
1.50
1.7
1.5
—
—
—
0
0
18
101
1.79
1.49
1.2
1.1
—
—
—
0
0
301
2690
1.16
1.42
3.4
3.3
0.63
0.76
ug/l
2.78
207
1765
29
189
1.55
1.41
2.2
1.9
1.76
1.66
mmol/l
0.22
29
182
7
29
2.42
1.39
3.7
1.9
—
—
—
0
0
5
17
2.95
1.36
3.0
6.3
8.22
8.52
mmol/l
—
5
17
22
136
1.63
1.33
2.0
1.8
—
—
—
0
0
33
225
1.48
1.32
1.4
1.3
—
—
—
0
0
15
84
1.80
1.27
2.0
2.3
689.67
626.58
ml
—
9
50
5
19
2.64
1.21
1.8
4.1
36.60
50.00
umol/l
—
5
14
18
110
1.65
1.15
1.9
2.0
—
—
—
0
0
7
30
2.34
1.12
1.0
1.1
—
—
—
0
0
8
40
2.01
1.12
1.5
1.9
—
—
—
0
0
25
168
1.50
1.10
1.4
1.1
0.96
1.88
u/ml
0.66
16
93
27
185
1.47
1.09
4.3
3.2
4.09
4.27
e9/l
0.13
27
185
12
68
1.77
1.00
1.2
1.0
—
—
—
0
0
20
131
1.54
1.00
2.0
1.5
9610.00
124199.67
e6/l
1.41
12
79
13
76
1.72
0.99
3.1
2.9
15.00
16.75
%
1.18
13
76
9
51
1.77
0.94
1.2
1.2
—
—
—
0
0
14
85
1.65
0.94
1.6
1.5
—
—
—
0
0
6
27
2.23
0.93
1.2
1.0
13.85
10.49
u/ml
—
6
18
55
685
0.79
0.92
2.0
1.8
3.44
3.48
mmol/l
0.10
42
506
14
89
1.58
0.81
1.1
1.0
155.11
305.07
ng/l
—
9
57
6
33
1.82
0.79
1.2
1.9
—
—
—
0
0
40
313
1.29
0.78
10.8
11.2
—
—
—
0
0
20
141
1.43
0.75
1.4
1.0
0.84
0.73
u/ml
0.10
14
54
17
241
0.70
0.72
2.4
1.7
—
—
—
0
0
20
143
1.41
0.70
1.4
1.0
2.34
4.10
u/ml
0.51
12
70
7
41
1.71
0.70
1.3
2.4
—
—
—
0
0
19
135
1.41
0.69
2.1
1.7
—
—
—
0
0
32
407
0.78
0.68
1.6
1.7
—
—
—
0
0
119
1060
1.14
0.64
1.6
1.5
—
—
—
0
0
19
139
1.37
0.60
1.3
1.3
—
—
—
0
0
13
89
1.47
0.58
1.1
1.0
832.75
641.55
ng/l
—
8
56
6
36
1.67
0.56
2.0
1.3
0.00
0.08
estimate
—
6
36
14
98
1.43
0.56
1.7
1.8
—
—
—
0
0
5
86
0.58
0.56
1.2
1.5
—
—
—
0
0
14
102
1.38
0.47
1.1
1.3
—
—
—
0
0
18
139
1.30
0.43
1.4
1.0
1.04
1.71
u/ml
0.43
12
71
14
105
1.34
0.41
1.4
1.1
—
—
—
0
0
7
101
0.69
0.39
2.7
2.6
—
—
—
0
0
10
71
1.41
0.39
3.7
2.8
7.14
8.03
mmol/l
—
10
71
6
46
1.31
0.33
1.5
1.3
14.17
10.57
mm/h
—
6
46
6
88
0.68
0.33
1.2
1.6
—
—
—
0
0
7
100
0.70
0.30
9.6
2.1
13.50
13.13
%
—
7
100
54
492
1.10
0.25
1.1
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
4.1
—
48.07
—
0
14
0
14
0.00
0.20
0.0
8.1
—
10.36
—
0
14
29
318
0.91
0.16
1.1
1.1
—
—
—
0
0
12
107
1.12
0.08
1.3
1.0
0.39
0.44
u/ml
—
6
36
81
786
1.03
0.08
1.7
1.4
—
—
—
0
0
26
245
1.06
0.07
5.0
3.4
0.97
0.83
nmol/l
0.62
20
198
9
101
0.89
0.06
1.2
1.2
—
—
—
0
0
27
256
1.06
0.06
1.2
1.3
142.53
208.00
miu/ml
—
9
118
84
856
0.98
0.04
6.7
3.9
—
—
—
0
0
16
166
0.96
0.00
1.1
1.1
—
—
—
0
0
16
166
0.96
0.00
1.1
1.1
—
—
—
0
0
30
296
1.01
0.00
1.2
1.2
—
—
—
0
0
16
162
0.99
0.00
2.2
2.1
33.19
32.52
pg
0.24
16
162
10
95
1.05
0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
4.4
—
97.38
—
0
8
14
140
1.00
-0.00
2.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
331.29
—
0
7
12
120
1.00
-0.00
1.5
1.0
15.60
4.85
u/ml
—
6
51
0
5
0.00
-0.00
0.0
1.0
—
34.26
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
0.08
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint SFN and mortality.

Females

Parameter HR [95% CI] p-value
SFN 2.127 [1.75, 2.58] < 0.001
Birth year 0.998 [0.99, 1.01] 0.556

During the follow-up period (1.1.1998 — 31.12.2019), 319 out of 1445 females with SFN died.

Males

Parameter HR [95% CI] p-value
SFN 1.787 [1.5, 2.13] < 0.001
Birth year 0.989 [0.98, 1.0] 0.059

During the follow-up period (1.1.1998 — 31.12.2019), 535 out of 2049 males with SFN died.

Mortality risk

Mortality risk for people of age

years, who have SFN.

N-year risk Females Males
1 0.152% 0.371%
5 1.346% 2.018%
10 3.672% 4.985%
15 6.693% 9.373%
20 10.957% 15.86%

Relationships between endpoints

Index endpoint: SFN – Small fibre neuropathy

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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