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Eustachian salpingitis and obstruction

DOID EFO Endpoint Browser PheWeb

H8_EUSTSALP

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H68
  • Hospital discharge: ICD-9 — 3816
  • Hospital discharge: ICD-8 — 3840[0-2]
  • Cause of death: ICD-10 — H68
  • Cause of death: ICD-9 — 3816
  • Cause of death: ICD-8 — 3840[0-2]

2 out of 7 registries used, show all original rules.

3940

4. Check minimum number of events

None

3940

5. Include endpoints

None

3940

6. Filter based on genotype QC (FinnGen only)

3622

Control definitions (FinnGen only)

Control exclude
H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 31754 13543 18131
Only index persons 30023 12880 17143
Unadjusted period prevalence (%)
Whole population 0.45 0.39 0.51
Only index persons 0.58 0.47 0.65
Median age at first event (years)
Whole population 5.11 5.81 4.58
Only index persons 5.10 5.83 4.54

-FinnGen-

Key figures

All Female Male
Number of individuals 3622 2077 1545
Unadjusted period prevalence (%) 0.73 0.74 0.71
Median age at first event (years) 7.23 7.84 6.39

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3736
Matched controls
37360
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H65.3
ICD-10 Finland
Chronic mucoid otitis media
128.7
307.7
392
34
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
307.7
1308
*
4122
FHL
Tympanostomy (tympanic tube)
151.5
307.7
344
25
UDC00
NOMESCO Finland
Ear microscopy
7.2
307.7
583
934
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
307.7
412
*
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
18.3
307.7
1959
2118
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
238.8
307.7
307
14
H65.2
ICD-10 Finland
Chronic serous otitis media
123.1
307.7
274
24
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
307.7
765
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
6.5
307.7
705
1299
38400
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) acuta
+∞
307.7
472
*
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
84.3
307.7
1221
214
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
249.9
307.7
441
20
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
65.9
307.7
292
48
DGW00
NOMESCO Finland
Dilatation of eustachian tube
+∞
300.1
284
*
DC1AD
NOMESCO Finland
Temporalbone CT
35.3
293.1
185
55
DFF00
NOMESCO Finland
Pure tone audiometry
5.3
258.1
582
1258
H66.9
ICD-10 Finland
Otitis media, unspecified
5.3
247.6
557
1200
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
231.7
220
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.1
227.8
748
2165
H68.0
ICD-10 Finland
Eustachian salpingitis
44.8
226.1
134
31
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
25.0
208.3
147
61
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
81.2
178.5
95
12
H65.0
ICD-10 Finland
Acute serous otitis media
11.1
172.9
187
177
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
15.1
139.5
124
85
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
136.3
130
*
DCD00
NOMESCO Finland
Myringoplasty
1302.7
130.0
126
*
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
125.7
120
*
4451
FHL
Guitar cutting
4.9
113.8
261
562
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
23.3
113.3
82
36
H74.1
ICD-10 Finland
Adhesive middle ear disease
522.1
103.1
102
*
H92.0
ICD-10 Finland
Otalgia
3.4
102.3
413
1336
R01AD08
ATC
fluticasone; nasal
2.1
99.6
1387
8117
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
9.1
97.9
121
137
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
6.6
95.2
156
245
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
14.5
93.9
85
60
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.3
90.5
380
1256
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
17.6
84.4
69
40
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
39.0
81.4
50
13
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
79.8
2186
15810
TDA90
NOMESCO Finland
Removal wax from ear
10.3
75.1
84
83
R01AD09
ATC
mometasone; nasal
1.8
70.9
1988
14266
H66
ICD-10 Finland
Suppurative and unspecified otitis media
4.3
69.9
189
462
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.0
66.4
1024
6047
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
99.0
62.0
68
7
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.5
60.9
411
1740
H69.0
ICD-10 Finland
Patulous Eustachian tube
16.1
59.8
51
32
EMB30
NOMESCO Finland
Adenotomy
6.2
57.7
100
166
H01
ICPC
Ear pain/earache
2.2
57.0
551
2724
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
23.0
56.4
41
18
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
55.3
53
*
H69.8
ICD-10 Finland
Other specified disorders of Eustachian tube
12.1
54.9
55
46
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
10.9
54.8
59
55
4141
FHL
Myringoplasty (also for reasons other than inflammation)
275.0
53.3
54
*
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
51.2
49
*
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
5.3
50.5
102
196
R01AD12
ATC
fluticasone furoate; nasal
1.7
47.6
1448
10250
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
7.4
47.0
68
93
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
47.0
45
*
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
47.0
45
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.3
46.0
378
1740
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
7.3
45.8
67
93
1450
FHL
Otomicroscopy
11.3
44.9
47
42
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
44.9
43
*
H29
ICPC
Ear symptom/complaint other
2.2
44.6
414
2004
J01FA10
ATC
azithromycin; systemic
1.6
42.0
2249
18092
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
67.9
41.1
47
7
ZXA10
NOMESCO Finland
Bilateral
2.0
40.8
538
2960
R01BA52
ATC
pseudoephedrine, combinations; oral
1.7
39.9
1091
7436
50300
ICD-8 Finland
Chronic sinusitis, Maxillaris cum empyemate
10.3
38.7
43
42
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
38.6
37
*
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
6.9
37.7
58
85
H02AB06
ATC
prednisolone; systemic
1.6
37.1
1602
12129
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
101.1
36.8
40
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.2
36.7
346
1680
DFF10
NOMESCO Finland
Measurement of acoustic impedance (tympanometry and reflex testing)
13.7
36.5
34
25
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
35.5
34
*
H02
ICPC
Hearing complaint
2.1
35.3
355
1767
H69.9
ICD-10 Finland
Eustachian tube disorder, unspecified
8.1
35.0
47
59
H71
ICPC
Acute otitis media/myringitis
4.7
34.8
81
176
4452
FHL
Tonsil surgery
2.6
34.7
204
803
J01CA04
ATC
amoxicillin; systemic
1.7
33.9
3067
27200
S02CA02
ATC
flumetasone and antiinfectives; otic
2.8
33.6
179
670
H60.8
ICD-10 Finland
Other otitis externa
3.0
33.4
153
528
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.2
33.4
134
428
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
+∞
33.4
32
*
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.2
32.7
134
433
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.6
31.3
182
713
DFF15
NOMESCO Finland
Speech audiometry
3.2
30.8
126
407
R01AD58
ATC
fluticasone, combinations; nasal
1.5
30.3
1143
8302
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.2
30.3
123
396
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
30.1
828
5589
H13
ICPC
Plugged feeling ear
1.8
29.5
505
2999
J01FA09
ATC
clarithromycin; systemic
1.5
29.1
1113
8091
ZXE00
NOMESCO Finland
One hour or less
1.5
28.2
1317
9971
H02AB04
ATC
methylprednisolone; systemic
1.8
28.1
465
2733
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
3.1
27.9
118
389
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.7
27.8
158
612
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.8
27.5
145
540
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
+∞
27.1
26
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.2
26.9
240
1137
DCD10
NOMESCO Finland
Tympanoplasty
75.7
26.8
30
*
UDM02
NOMESCO Finland
Sinoscopy
3.3
26.7
101
311
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
34.3
26.5
34
10
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
2.8
26.1
137
509
J01DA01
ATC
[U] cefalexin
1.4
25.7
2140
17983
J35.2
ICD-10 Finland
Hypertrophy of adenoids
4.0
25.3
72
183
48509
ICD-8 Finland
Bronchopneumonia, unspecified
4.1
24.7
68
169
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
24.1
416
2470
J32.4
ICD-10 Finland
Chronic pansinusitis
3.5
24.0
83
242
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.4
23.3
158
666
J01DA08
ATC
[U] cefaclor
1.8
23.1
366
2116
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
22.9
1282
9949
H60.3
ICD-10 Finland
Other infective otitis externa
3.1
22.8
94
306
Z96.2
ICD-10 Finland
Presence of otological and audiological implants
84.0
22.7
25
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.2
22.5
199
940
J01AA02
ATC
doxycycline; systemic
1.5
22.4
2654
23478
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.5
22.0
142
585
Z3229
NOMESCO Finland
Other healthcare associate professional
2.0
21.9
235
1195
H61.2
ICD-10 Finland
Impacted cerumen
2.1
21.8
216
1066
J34.2
ICD-10 Finland
Deviated nasal septum
2.1
21.6
222
1111
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
2.3
21.5
169
760
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
21.5
344
1995
H60
ICD-10 Finland
Otitis externa
2.0
21.4
239
1233
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.0
20.8
93
317
H04
ICPC
Ear discharge
2.7
20.5
107
397
J01DB01
ATC
cefalexin; oral
1.5
20.4
3011
27457
46699
ICD-8 Finland
Acute bronchitis and bronchiolitis
3.1
19.8
84
278
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
19.8
19
*
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
73.9
19.7
22
*
DEB30
NOMESCO Finland
Radical mastoidectomy
105.6
19.6
21
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
19.5
1042
7968
H60.4
ICD-10 Finland
Cholesteatoma of external ear
19.5
19.5
29
15
J01DC02
ATC
cefuroxime; systemic
2.0
19.4
211
1077
J01DA06
ATC
[U] cefuroxime
1.6
19.3
447
2865
H72
ICD-10 Finland
Perforation of tympanic membrane
31.4
19.2
25
8
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.0
18.8
81
271
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
18.8
18
*
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
+∞
18.8
18
*
R5140
NOMESCO Finland
Monitoring the use of the aid
1.7
18.8
347
2096
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
4.1
18.7
51
126
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
7.9
18.3
25
32
N07CA01
ATC
betahistine; oral
2.1
18.2
174
848
H61.8
ICD-10 Finland
Other specified disorders of external ear
4.4
18.0
45
104
H68
ICD-10 Finland
Eustachian salpingitis and obstruction
5.5
17.9
34
62
4741A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PALATINAE]
4.4
17.8
44
101
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
3.9
17.6
51
132
48609
ICD-8 Finland
Pneumonia, unspecified
3.0
17.0
75
254
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
16.7
1292
10453
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
16.7
16
*
4221
FHL
Polyp removal from the nasal cavity, sinus puncture or irrigation, or biopsy under general anesthesia or operating room
4.0
16.6
46
115
R03AC02
ATC
salbutamol; inhalant
1.3
16.6
1940
16691
R06.0
ICD-10 Finland
Dyspnoea
1.4
16.5
731
5377
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
170.7
16.5
17
*
DHB50
NOMESCO Finland
Turbinoplasty
2.3
16.4
121
530
J34.3
ICD-10 Finland
Hypertrophy of nasal turbinates
2.5
16.3
100
403
G47.3
ICD-10 Finland
Sleep apnoea
1.4
16.3
759
5635
SPAT1043
SPAT
Audiometry
2.0
16.3
191
1002
R06AE07
ATC
cetirizine; oral
1.3
16.2
1563
13057
A02BC05
ATC
esomeprazole; systemic
1.4
16.1
1241
10023
R01AD59
ATC
mometasone, combinations; nasal
1.7
16.1
315
1931
J01MA12
ATC
levofloxacin; systemic
1.6
16.1
460
3094
DAX08
NOMESCO Finland
Fitting of hearing aid
2.4
15.8
103
428
Q35.1
ICD-10 Finland
Cleft hard palate
33.5
15.7
20
6
H93.1
ICD-10 Finland
Tinnitus
1.8
15.7
226
1268
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
15.7
753
5619
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
15.6
15
*
DCA40
NOMESCO Finland
Fat patching or other similar technique without opening of tympanic membrane
+∞
15.6
15
*
H73.1
ICD-10 Finland
Chronic myringitis
160.7
15.5
16
*
WX780
NOMESCO Finland
Remote monitoring CPAP
1.9
15.1
181
957
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.9
15.1
186
993
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
15.1
2253
19953
R42
ICD-10 Finland
Dizziness and giddiness
1.5
15.0
604
4357
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
14.8
996
7851
7490A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS COMPLETA]
56.9
14.8
17
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.3
14.7
111
492
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
14.7
1091
8732
SPAT1172
SPAT
Guidance concerning hydration
3.9
14.7
42
108
4224
FHL
Endonasal anthrostomy
3.7
14.6
45
122
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
6.6
14.5
23
35
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
14.3
604
4393
49099
ICD-8 Finland
Bronchitis, unspecified
3.7
14.3
44
119
4364
FHL
Pharyngeal tongue plastic
27.3
14.3
19
7
J33.8
ICD-10 Finland
Other polyp of sinus
2.8
14.0
70
255
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
14.0
1052
8426
R01AD05
ATC
budesonide; nasal
1.7
14.0
252
1511
EMB10
NOMESCO Finland
Tonsillectomy
1.7
13.6
273
1684
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
75.4
13.6
15
*
WX723
NOMESCO Finland
CPAP therapy
1.9
13.6
170
913
38299
ICD-8 Finland
Unspecified otitis media with mastoiditis
+∞
13.5
13
*
J01FF01
ATC
clindamycin; systemic
1.4
13.5
826
6404
H92.1
ICD-10 Finland
Otorrhoea
18.3
13.4
20
11
R06AX27
ATC
desloratadine; oral
1.3
13.3
1135
9250
4740A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Chronic tonsillitis
2.0
13.2
145
744
SPAT1263
SPAT
Sampling
1.3
13.1
1277
10591
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.6
13.1
334
2187
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
13.0
1016
8168
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
13.0
604
4467
R03DC03
ATC
montelukast; oral
1.4
12.9
569
4170
M01AE02
ATC
naproxen; oral, rectal
1.3
12.8
1927
16911
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.0
12.8
138
705
S02AA03
ATC
boric acid; otic
4.1
12.7
34
83
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
12.6
347
2311
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
3.0
12.6
54
181
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
+∞
12.5
12
*
WX402
NOMESCO Finland
General anaesthesia
1.4
12.5
738
5681
N02BE01
ATC
paracetamol; systemic, rectal
1.4
12.4
3056
28594
H65
ICD-10 Finland
Nonsuppurative otitis media
2.9
12.4
56
193
J01DA09
ATC
[U] cefadroxil
1.4
12.4
831
6521
J01DC04
ATC
cefaclor; oral
3.1
12.3
50
162
J02AC01
ATC
fluconazole; systemic
1.3
12.3
1336
11222
4129
FHL
Other measure in this category
37.7
12.2
15
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
12.1
514
3739
A02BC02
ATC
pantoprazole; systemic
1.3
12.0
2123
18939
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
11.7
1326
11175
XX3DW
NOMESCO Finland
Time consuming IT work
1.7
11.7
239
1482
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
11.7
687
5278
H02AB07
ATC
prednisone; oral
1.5
11.7
349
2366
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.3
11.7
90
404
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
11.6
1461
12480
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
11.6
547
4052
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
11.4
549
4076
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
11.4
183
1061
DCB10
NOMESCO Finland
Freeing of adhesions of middle ear
120.4
11.4
12
*
R03AK08
ATC
formoterol and beclometasone; inhalant
1.9
11.4
143
769
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
11.4
292
1914
R5120
NOMESCO Finland
Preparation of an aid
2.6
11.3
62
238
74920
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis unilateralis
17.1
11.2
17
10
J01FA06
ATC
roxithromycin; oral
1.3
11.2
1207
10099
50709
ICD-8 Finland
Hay fever, Unspecified
4.7
11.2
25
53
R01AD11
ATC
triamcinolone; nasal
1.6
11.1
273
1772
00920
ICD-8 Finland
Diarrhoeal disease, Gastroenteritis (acuta) (infectiosa)
1.9
11.0
132
700
DCA30
NOMESCO Finland
Exploration of middle ear
43.4
10.9
13
*
J01FA15
ATC
telithromycin; oral
1.5
10.9
306
2046
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
3.6
10.9
35
98
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
15.5
10.8
17
11
R01AD01
ATC
beclometasone; nasal
1.4
10.8
510
3776
R74
ICPC
Upper respiratory infection acute
1.3
10.8
1375
11734
R03BA05
ATC
fluticasone; inhalant
1.4
10.7
557
4192
ZFX00
NOMESCO Finland
Use of balloon dilatation
21.5
10.7
15
7
J01FA01
ATC
erythromycin; systemic
1.4
10.6
470
3438
1451
FHL
Otomicroscopy and paper place
60.2
10.6
12
*
SPAT1153
SPAT
Removal of sutures
1.3
10.5
732
5760
E0000UV, ,
ATC
1.3
10.5
1325
11283
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
10.5
139
762
4151
FHL
Reoperation for chronic otitis media
110.3
10.4
11
*
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
110.3
10.4
11
*
3811A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic serous otitis media
+∞
10.4
10
*
38200
ICD-8 Finland
Acute / Acute otitis media with mastoiditis
+∞
10.4
10
*
M01AH05
ATC
etoricoxib; oral
1.3
10.3
2172
19615
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
10.2
2566
23641
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
10.2
368
2593
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
3.6
10.1
32
89
J01MA02
ATC
ciprofloxacin; systemic
1.3
10.0
1026
8504
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
10.0
1131
9492
UJF32
NOMESCO Finland
Coloscopy
1.4
9.9
597
4592
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
9.9
696
5480
J45
ICD-10 Finland
Asthma
1.5
9.8
341
2382
J33.0
ICD-10 Finland
Polyp of nasal cavity
2.1
9.8
91
441
J37.0
ICD-10 Finland
Chronic laryngitis
2.0
9.7
97
483
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
55.1
9.6
11
*
R06AX13
ATC
loratadine; oral
1.4
9.6
521
3941
M03BX02
ATC
tizanidine; oral
1.2
9.4
2231
20304
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
100.3
9.4
10
*
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
9.4
9
*
7490B
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS INCOMPLETA]
+∞
9.4
9
*
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
9.3
620
4840
H73.0
ICD-10 Finland
Acute myringitis
4.5
9.3
22
49
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.8
9.3
136
770
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
9.2
640
5027
SPAT1211
SPAT
Application of soft bandage
1.6
9.2
204
1293
WX002
NOMESCO Finland
Sedation and analgesia
1.4
9.2
442
3280
DPA30
NOMESCO Finland
Sphenotomy
3.5
9.1
30
86
A02BC01
ATC
omeprazole; systemic
1.3
9.0
680
5402
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
3.3
9.0
33
101
N02AX02
ATC
tramadol; systemic, rectal
1.3
8.9
1197
10217
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.4
8.9
353
2529
D82
ICPC
Teeth/gum disease
1.2
8.8
1345
11644
WX320
NOMESCO Finland
Spinalanesthesy
1.3
8.8
611
4797
DE2DG
NOMESCO Finland
Acoustic channel very extensive MRI examination with high intensity magnet
10.7
8.8
16
15
AA1AD
NOMESCO Finland
CT of head and brain
1.3
8.8
627
4943
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
8.7
1387
12059
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
2.1
8.7
83
407
Q35.9
ICD-10 Finland
Cleft palate, unspecified
50.1
8.7
10
*
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
8.7
2469
22818
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
8.6
709
5702
P01AB01
ATC
metronidazole; oral, rectal
1.2
8.5
1235
10623
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.3
8.5
583
4568
7492A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS UNILATERALIS COMPLETA]
20.1
8.5
12
6
R02
ICPC
Shortness of breath/dyspnoea
1.4
8.4
322
2291
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
1.7
8.4
151
906
H74.0
ICD-10 Finland
Tympanosclerosis
90.3
8.4
9
*
R03CC02
ATC
salbutamol; systemic
1.7
8.4
146
869
H91
ICD-10 Finland
Other hearing loss
3.4
8.3
29
86
4362
FHL
Nozzle reconstruction
+∞
8.3
8
*
3851A
ICD-9 Finland
Other disorders of middle ear and mastoid, Adhesive middle ear disease
+∞
8.3
8
*
J20
ICD-10 Finland
Acute bronchitis
1.4
8.3
330
2365
R03AK07
ATC
formoterol and budesonide; inhalant
1.3
8.3
730
5914
ZXA05
NOMESCO Finland
Left side
1.3
8.3
521
4030
R01BA01
ATC
phenylpropanolamine; oral
1.7
8.3
134
782
H81.3
ICD-10 Finland
Other peripheral vertigo
2.2
8.3
66
302
ZXA00
NOMESCO Finland
Right side
1.3
8.3
565
4423
N03AX16
ATC
[U] pregabalin
1.3
8.2
591
4661
S01AA01
ATC
chloramphenicol; ophthalmic
1.8
8.1
121
690
ZXC10
NOMESCO Finland
Use of laser
2.2
8.1
62
279
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
1.5
8.0
259
1785
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.3
7.9
492
3797
R4135
NOMESCO Finland
Rehabilitation for hearing problems
3.3
7.9
29
89
R03BA02
ATC
budesonide; inhalant
1.3
7.9
536
4192
M79.6
ICD-10 Finland
Pain in limb
1.2
7.9
1398
12259
R05FB02
ATC
cough suppressants and expectorants; systemic
1.3
7.9
925
7758
UJF30
NOMESCO Finland
Ileoscopy through colon
1.5
7.8
285
2010
R52.9
ICD-10 Finland
Pain, unspecified
1.4
7.8
307
2196
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.7
7.8
146
887
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
2.0
7.8
86
446
S02AA30
ATC
antiinfectives, combinations; otic
1.8
7.8
110
618
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
2.9
7.7
34
117
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.5
7.6
233
1587
SGA01
NOMESCO Finland
Emergency treatment
1.3
7.6
634
5095
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.2
7.6
988
8377
UDC10
NOMESCO Finland
Tympanoscopy
25.1
7.6
10
*
L15
ICPC
Knee symptom/complaint
1.3
7.5
663
5366
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.5
7.5
198
1309
S18
ICPC
Laceration/cut
1.2
7.4
1263
11009
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
2.7
7.4
37
136
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
2.6
7.4
41
159
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.6
7.4
154
962
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
7.3
1903
17276
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.6
7.3
181
1178
R96
ICPC
Asthma
1.5
7.3
245
1701
3816A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Obstruction of Eustachian tube
+∞
7.3
7
*
DDD20
NOMESCO Finland
Interposition between eardrum and footplate of stapes
+∞
7.3
7
*
50499
ICD-8 Finland
Deflected nasal septum
3.4
7.2
25
74
1290
FHL
Epipharyngoscopy
15.8
7.2
11
7
H70
ICPC
Otitis externa
2.1
7.2
63
300
05209
ICD-8 Finland
Chickenpox, Unspecified
3.9
7.2
20
51
74929
ICD-8 Finland
Cleft palate and cleft lip, Unspecified
30.1
7.1
9
*
J01
ICD-10 Finland
Acute sinusitis
1.5
7.1
213
1445
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.4
7.1
286
2055
R03AC03
ATC
terbutaline; inhalant
1.4
7.1
402
3057
J35.1
ICD-10 Finland
Hypertrophy of tonsils
2.1
7.1
66
322
R06.5
ICD-10 Finland
Mouth breathing
1.4
7.1
279
1998
C05AA08
ATC
fluocortolone; rectal, topical
1.4
7.1
337
2494
SPAT1262
SPAT
Handing over of treatment supplies
1.4
7.1
380
2868
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
7.1
1035
8877
UKC02
NOMESCO Finland
Cystoscopy
1.4
7.0
272
1941
P85
ICPC
Mental retardation
8.8
7.0
14
16
Z01.2
ICD-10 Finland
Dental examination
1.2
7.0
1626
14583
SPAT1215
SPAT
Assessment of need for medical rehabilitation
1.8
7.0
97
542
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
7.0
668
5459
S01GX01
ATC
cromoglicic acid; ophthalmic
1.3
6.9
698
5739
R51.80
ICD-10 Finland
Headache
1.3
6.9
547
4363
78159
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Laesio loquendi alia sive NUD
6.3
6.9
17
27
RK520, ,
NOMESCO Finland
6.3
6.9
17
27
L17
ICPC
Foot/toe symptom/complaint
1.2
6.9
833
6992
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
2.9
6.9
31
108
SPAT1260
SPAT
Consultation of another employee
1.3
6.9
414
3179
C09CA06
ATC
candesartan; oral
1.3
6.9
659
5387
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
4.1
6.8
18
44
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.5
6.8
197
1329
R55
ICD-10 Finland
Syncope and collapse
1.5
6.8
224
1552
4161
FHL
Exploratory tympanotomy
40.1
6.8
8
*
J34.1
ICD-10 Finland
Cyst and mucocele of nose and nasal sinus
2.1
6.8
57
268
SPAT1310
SPAT
Counselling related to known health issue
1.2
6.7
816
6851
SPAT1312
SPAT
General health counselling
1.2
6.7
881
7463
DC1AI
NOMESCO Finland
Cone beam CT of ear
22.5
6.7
9
*
Q37.0
ICD-10 Finland
Cleft hard palate with bilateral cleft lip
22.5
6.7
9
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
6.6
651
5334
J31.1
ICD-10 Finland
Chronic nasopharyngitis
2.8
6.6
32
116
Y0599
ICD-8 Finland
Investigation of digestive system
2.5
6.6
40
163
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
6.6
2620
24637
K57.9
ICD-10 Finland
Diverticular disease of intestine, part unspecified, without perforation or abscess
2.3
6.6
45
194
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.4
6.6
291
2129
GD1AD
NOMESCO Finland
Thorax CT examination
1.7
6.5
123
750
A11CC03
ATC
alfacalcidol; systemic
2.1
6.5
55
259
J30.0
ICD-10 Finland
Vasomotor rhinitis
1.9
6.5
79
424
N03AX12
ATC
[U] gabapentin; oral
1.3
6.5
410
3172
J35.0
ICD-10 Finland
Chronic tonsillitis
1.5
6.5
223
1559
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.4
6.4
281
2050
DCA10, ,
SPAT
70.0
6.4
7
*
38410, ,
ICD-8 Finland
70.0
6.4
7
*
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
2.0
6.4
66
335
SPAT1377
SPAT
Polysomnography
1.8
6.4
93
528
A02BA02
ATC
ranitidine; systemic
1.3
6.4
385
2957
ZXD20
NOMESCO Finland
Day surgery
1.4
6.4
334
2511
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.6
6.4
159
1039
E66.01
ICD-10 Finland
Obesity due to excess calories
1.4
6.4
346
2617
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.6
6.4
149
960
R03AK11
ATC
formoterol and fluticasone; inhalant
1.9
6.3
72
378
R53
ICD-10 Finland
Malaise and fatigue
1.2
6.3
785
6604
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.5
6.3
223
1566
XLA10, ,
NOMESCO Finland
1.7
6.3
121
742
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
2.8
6.3
30
108
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.2
6.3
833
7059
H66.2
ICD-10 Finland
Chronic atticoantral suppurative otitis media
+∞
6.2
6
*
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
+∞
6.2
6
*
3824A
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified suppurative otitis media
+∞
6.2
6
*
H74.4
ICD-10 Finland
Polyp of middle ear
+∞
6.2
6
*
DEB35
NOMESCO Finland
Radical mastoidectomy with tympanoplasty
+∞
6.2
6
*
M79.1
ICD-10 Finland
Myalgia
1.3
6.2
502
4012
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.8
6.2
92
525
XKD00
NOMESCO Finland
Uroflowmetry
1.4
6.2
221
1555
H27
ICPC
Fear of ear disease
2.6
6.2
35
138
4222
FHL
Endonasal etmoidectomy
3.8
6.1
18
48
H72
ICPC
Serous otitis media
12.5
6.1
10
8
R03BC03
ATC
nedocromil; inhalant
1.5
6.1
159
1051
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.4
6.1
292
2167
WX204
NOMESCO Finland
Axillary plexus blockaced
1.8
6.1
90
515
XF405
NOMESCO Finland
Symptom ECG
3.6
6.0
19
53
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
6.0
617
5079

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
620
3528
1.91
42.64
2.1
1.7
—
—
—
0
0
1416
11201
1.43
22.77
10.1
9.4
1.12
1.14
inr
0.66
1177
9237
468
2945
1.67
21.85
4.3
4.0
30.18
30.74
%
0.53
337
2181
1409
11568
1.35
16.52
6.8
6.4
1.22
1.21
mmol/l
2.11
1302
10859
1795
15287
1.34
16.39
7.3
6.9
2.88
2.84
%
0.40
1687
14542
1791
15268
1.33
16.15
7.4
7.0
0.71
0.69
%
0.39
1682
14489
388
2512
1.61
15.98
3.6
3.4
—
—
—
0
0
1565
13096
1.34
15.98
7.2
6.9
1.21
1.21
mmol/l
0.89
1311
11446
1793
15309
1.33
15.90
7.4
7.0
8.47
8.54
%
0.52
1687
14580
1818
15564
1.33
15.77
6.9
6.7
56.68
56.46
%
0.38
1736
15042
1234
9983
1.35
15.74
3.2
2.9
28.23
43.99
ng/l
0.73
656
5198
340
2149
1.64
15.42
3.8
3.8
7.37
7.35
ph
0.95
236
1612
1835
15813
1.32
14.83
7.2
6.8
28.92
29.15
%
0.47
1749
15189
2537
22891
1.34
14.71
8.3
7.7
74.47
74.47
u/l
0.00
2407
21977
319
2008
1.64
14.70
3.8
3.5
1.22
1.23
mmol/l
2.42
282
1749
1908
16661
1.30
13.41
5.1
4.8
6.45
6.50
mmol/l
0.44
1788
15611
536
3870
1.45
13.14
1.6
1.5
—
—
—
0
0
113
536
2.14
12.75
3.5
3.4
2.25
2.17
mmol/l
0.12
83
318
1742
15094
1.29
12.74
6.0
6.0
10.50
10.97
umol/l
0.96
1633
14452
258
1612
1.65
12.23
3.9
3.1
7.41
7.41
ph
0.63
213
1347
1903
16729
1.28
12.20
7.0
6.8
0.55
0.55
e9/l
0.06
1673
14779
1905
16750
1.28
12.19
7.0
6.8
0.04
0.04
e9/l
0.06
1673
14785
549
4036
1.42
12.15
1.2
1.2
—
—
—
0
0
123
614
2.04
12.14
3.8
3.6
3.89
4.02
e9/l
0.30
123
614
1941
17124
1.28
12.01
7.0
6.9
1.96
1.96
e9/l
0.07
1747
15447
739
5732
1.36
11.83
2.9
3.0
684.45
825.47
ng/l
0.72
580
4657
470
3384
1.44
11.63
2.2
2.2
366.40
366.04
nmol/l
0.02
437
3167
1654
14354
1.27
11.51
11.4
10.2
0.00
0.00
e9/l
0.14
1351
11745
3365
32117
1.48
11.40
14.5
12.5
20.87
20.97
mg/l
0.06
2784
25686
387
2695
1.49
11.37
1.4
1.3
258.75
251.22
u/ml
0.03
369
2530
1953
17311
1.27
11.34
7.2
7.1
0.19
0.19
e9/l
0.42
1741
15518
260
1659
1.61
11.33
3.9
3.1
5.19
5.15
kpa
0.37
248
1599
1429
12222
1.27
11.07
5.2
5.1
36.98
37.13
g/l
0.48
1342
11605
2752
25498
1.30
10.94
4.9
4.4
14.44
14.43
pmol/l
0.13
2562
24179
540
4030
1.40
10.89
2.0
2.0
—
—
—
0
0
143
782
1.86
10.85
3.7
3.4
58.27
58.13
%
0.04
143
782
776
6136
1.33
10.83
1.3
1.3
6.14
8.80
u/ml
0.76
290
2667
467
3433
1.41
10.25
7.2
6.8
1.04
1.04
mmol/l
0.23
440
3241
1841
16319
1.25
10.24
3.4
3.4
0.00
6.88
estimate
3.93
448
3367
1120
9368
1.28
10.20
2.9
2.7
56.72
58.52
u/l
0.40
1022
8827
83
382
2.20
10.17
1.6
1.7
1.99
1.69
mmol/l
0.83
83
375
1820
16164
1.25
9.77
3.4
3.3
0.00
0.00
estimate
2.09
447
3342
3130
29655
1.34
9.72
5.8
5.2
1.76
1.75
mu/l
0.18
2945
28309
581
4466
1.36
9.70
3.8
3.7
0.83
0.83
mmol/l
0.00
555
4260
153
886
1.76
9.65
4.1
3.5
24.42
24.78
mmol/l
1.20
146
829
68
297
2.31
9.46
1.4
1.2
2.03
2.00
u/ml
0.01
28
155
1839
16393
1.24
9.40
3.4
3.4
0.02
0.11
estimate
0.49
426
3194
1614
14189
1.24
9.35
2.7
2.5
73.81
73.28
nmol/l
0.32
1492
13380
2031
18306
1.24
9.35
9.4
10.0
4.00
4.02
e9/l
0.16
1764
16138
2096
18988
1.24
9.08
4.3
3.8
1005.51
970.98
e6/l
0.01
23
208
373
2698
1.42
8.95
3.5
2.7
10.31
10.60
g/l
0.76
342
2526
858
7039
1.28
8.92
1.8
1.6
19.72
19.69
nmol/l
0.02
715
6265
178
1101
1.65
8.84
4.2
3.4
—
—
—
0
0
3118
29626
1.32
8.71
4.6
4.1
5.76
5.75
mmol/l
0.14
2890
28062
84
414
2.05
8.69
1.3
1.3
—
—
—
0
0
60
259
2.34
8.61
2.9
2.5
—
—
—
0
0
2785
29418
0.79
8.49
16.1
15.5
333.82
333.77
g/l
0.12
2767
29282
1099
9338
1.25
8.44
2.4
2.2
—
—
—
0
0
664
5305
1.31
8.40
1.4
1.4
429.12
528.42
titre
0.78
125
1045
3087
29326
1.30
8.38
5.5
5.0
37.93
37.80
mmol/mol
0.36
2902
28190
941
7859
1.26
8.38
1.5
1.5
2.18
2.28
g/l
1.64
623
5308
296
2079
1.46
8.32
2.0
1.9
1.26
1.29
g/l
0.15
274
1968
173
1081
1.63
8.27
1.5
1.3
—
—
—
0
0
1332
11583
1.23
8.23
2.1
1.9
99.43
97.61
pmol/l
0.70
730
6469
648
5180
1.30
8.15
2.7
2.7
548.21
538.90
mosm/kgh2o
0.44
586
4539
1135
9710
1.24
8.14
3.0
2.7
0.07
0.05
estimate
0.11
383
2736
354
2584
1.41
8.06
4.9
4.7
0.60
0.67
%
0.21
99
696
457
3485
1.35
7.97
1.4
1.4
—
—
—
0
0
105
578
1.84
7.90
4.3
3.1
—
—
—
0
0
660
5310
1.30
7.89
2.8
2.8
109.41
109.74
ug/g
0.01
516
4344
886
7395
1.26
7.86
1.7
1.8
0.91
0.89
mg/l
0.09
652
5475
471
3618
1.35
7.83
1.9
1.7
1168.12
1160.24
nmol/l
0.06
345
2855
992
8396
1.25
7.77
3.5
3.5
0.00
0.00
estimate
2.03
432
3144
58
261
2.24
7.60
2.3
2.0
16.52
22.26
mg/l
0.53
27
108
928
7834
1.25
7.39
4.6
4.1
7.40
7.40
ph
0.26
653
5451
77
396
1.96
7.15
1.6
1.4
—
—
—
0
0
1901
17282
1.20
7.14
3.5
3.2
110.40
98.11
ug/l
0.64
1805
16571
77
397
1.96
7.10
1.6
1.3
0.33
0.40
g/l
1.24
47
282
1487
13215
1.21
7.10
1.9
1.8
1.47
1.44
mmol/l
0.72
1222
11748
77
398
1.95
7.05
1.6
1.3
2.99
3.17
g/l
0.34
48
284
77
398
1.95
7.05
1.6
1.3
6.48
6.81
g/l
0.39
47
285
591
4753
1.29
7.03
2.8
2.5
14.10
14.47
umol/l
0.65
557
4472
1763
15938
1.20
6.97
2.9
2.6
—
—
—
0
0
888
7503
1.24
6.95
2.4
2.3
2.57
2.65
mg/l
0.71
766
6584
2694
25357
1.22
6.90
3.6
3.3
42.61
41.56
u/l
0.32
2561
24505
187
1251
1.52
6.72
2.1
1.6
5.00
10.37
iu/ml
—
9
46
521
4149
1.30
6.67
2.7
3.1
4.02
4.67
e9/l
2.61
445
3751
827
6975
1.24
6.54
2.4
2.2
—
—
—
0
0
351
2652
1.36
6.49
5.1
5.2
0.12
0.36
%
0.55
89
579
327
2446
1.37
6.45
2.0
1.9
0.00
0.03
estimate
1.95
72
607
344
2597
1.36
6.40
5.0
5.0
0.09
0.11
%
0.18
88
614
130
812
1.62
6.31
1.8
1.4
20.48
5.36
iu/ml
—
6
19
191
1305
1.49
6.23
2.1
2.0
0.04
0.55
estimate
0.47
50
477
801
6764
1.23
6.23
1.4
1.3
28.63
23.67
iu/ml
0.53
220
1923
59
292
2.04
6.15
4.3
2.6
—
—
—
0
0
821
6967
1.23
6.08
2.7
2.6
—
—
—
0
0
539
4368
1.27
6.00
2.8
2.5
2.43
2.41
g/l
0.24
501
4076
130
823
1.60
5.99
1.4
1.4
310.99
295.61
ug/g
0.28
70
420
949
8191
1.21
5.91
2.1
2.2
152.07
229.39
u/l
2.55
894
7862
3503
34165
1.41
5.91
11.8
10.4
28.72
28.18
u/l
0.77
3405
33557
3239
31253
1.27
5.81
15.0
12.9
139.63
139.62
mmol/l
0.13
3171
30658
330
2522
1.34
5.67
2.9
2.5
0.23
0.23
g/l
0.10
316
2365
78
437
1.80
5.65
3.0
2.1
—
—
—
0
0
3643
35835
1.67
5.65
21.6
18.9
90.15
90.09
fl
0.33
3607
35612
3643
35836
1.67
5.63
21.6
18.9
30.15
30.15
pg
0.02
3607
35613
3644
35849
1.67
5.62
21.8
19.0
6.73
6.64
e9/l
1.47
3582
35246
657
5490
1.24
5.58
1.8
1.6
30943842.10
27116960.91
pmol/l
0.06
530
4831
214
1528
1.42
5.58
1.8
1.7
—
—
—
0
0
3643
35840
1.66
5.57
22.1
19.3
41.22
42.09
%
2.09
3604
35603
162
1097
1.50
5.55
1.6
2.0
0.24
0.23
g/l
0.63
156
1049
150
1000
1.52
5.54
1.2
1.3
2.75
3.33
u/ml
—
10
89
3643
35843
1.66
5.53
21.7
19.0
4.61
4.62
e12/l
0.45
3579
35260
167
1139
1.49
5.53
1.6
2.0
1.20
1.18
g/l
0.26
160
1090
3644
35858
1.66
5.49
21.8
19.1
138.35
138.61
g/l
0.55
3608
35631
141
930
1.54
5.47
3.5
3.8
429.36
523.21
mg/l
0.23
72
456
350
2717
1.32
5.41
5.0
4.9
0.66
0.94
%
1.18
93
734
889
7691
1.20
5.33
4.8
4.3
8.17
8.57
mg/mmol
0.11
537
5070
491
3990
1.27
5.33
2.9
2.5
23.76
24.41
%
0.54
454
3756
3640
35822
1.63
5.31
21.8
19.0
260.49
259.18
e9/l
0.62
3586
35299
149
1006
1.50
5.20
1.2
1.3
11.61
9.98
u/ml
0.09
17
153
1029
9044
1.19
5.16
1.4
1.4
2.08
1.61
u/ml
0.40
302
2776
3241
31364
1.25
5.07
15.3
13.0
3.92
3.94
mmol/l
2.56
3162
30691
107
677
1.60
5.00
1.9
1.7
0.75
0.74
g/l
0.02
76
535
775
6656
1.21
4.99
4.6
4.1
—
—
—
0
0
143
971
1.49
4.88
2.2
1.9
1.48
1.40
g/l
0.45
119
846
157
1087
1.46
4.86
1.2
1.3
45.83
31.29
u/ml
—
8
54
471
3851
1.26
4.85
1.2
1.2
—
—
—
0
0
870
7588
1.19
4.71
3.9
3.7
45.51
50.08
mg/l
0.28
542
5022
46
231
2.00
4.69
1.1
1.1
—
—
—
0
0
1460
13296
1.16
4.62
3.0
3.1
6.17
6.18
ph
0.08
850
7927
64
364
1.77
4.49
2.8
2.7
1343.22
1308.46
e6/l
0.10
55
312
887
7792
1.18
4.38
2.5
2.4
331.94
329.81
umol/l
0.27
804
7162
3490
34169
1.32
4.36
16.9
14.5
74.37
73.41
umol/l
1.35
3456
33865
172
1241
1.40
4.30
1.2
1.2
—
—
—
0
0
951
8442
1.17
4.10
5.4
4.6
—
—
—
0
0
878
7745
1.17
4.10
3.4
2.9
0.25
0.31
e6/l
0.79
643
5507
299
2372
1.28
3.97
3.4
3.7
4.53
4.63
pmol/l
0.77
276
2162
3301
32157
1.23
3.91
4.7
4.3
1.39
1.42
mmol/l
3.48
3120
30873
1255
11411
1.15
3.89
3.4
3.4
30.77
31.33
u/l
0.23
1185
10869
1184
10722
1.15
3.88
4.0
3.6
70.20
70.89
e6/l
0.01
827
7318
154
1111
1.40
3.88
3.2
3.0
1.02
1.02
ratio
1.27
138
985
269
2114
1.29
3.85
1.6
1.7
266.33
286.82
mu/l
0.62
239
1933
34
166
2.06
3.80
2.7
2.2
670.52
647.82
ml
0.08
25
116
83
531
1.58
3.79
2.0
2.0
4.88
5.39
mmol/24h
0.80
77
490
94
619
1.53
3.79
2.4
2.4
5.68
6.63
umol/l
0.36
65
465
28
127
2.21
3.76
1.5
1.8
10.96
12.24
u/l
0.60
28
121
3307
32246
1.22
3.73
4.7
4.3
4.72
4.77
mmol/l
2.29
3132
31072
1041
9370
1.15
3.68
3.0
3.2
2.34
2.35
mmol/l
0.52
942
8751
272
2156
1.28
3.66
1.4
1.4
—
—
—
0
0
201
1530
1.33
3.64
1.8
2.0
2.94
6.77
iu/ml
3.23
31
406
1390
12773
1.14
3.63
3.3
3.2
1.33
0.02
estimate
0.50
382
2827
20
79
2.54
3.62
1.4
1.3
—
—
—
0
0
32
156
2.06
3.60
1.0
1.1
8.09
12.35
u/ml
—
7
30
27
123
2.20
3.60
1.3
1.5
0.15
0.02
estimate
0.38
27
123
50
284
1.77
3.59
2.7
2.2
13.60
13.96
%
0.10
50
279
51
296
1.73
3.42
2.8
2.2
71.47
73.49
%
0.36
51
287
12
32
3.76
3.38
1.2
1.1
—
—
—
0
0
860
7679
1.16
3.36
4.1
4.0
94.29
94.28
%
0.00
840
7510
287
2319
1.26
3.32
1.2
1.2
—
—
—
0
0
37
197
1.89
3.29
1.2
1.1
29.33
25.00
u/ml
—
9
24
273
2198
1.26
3.26
10.1
8.7
8.18
7.94
mmol/l
0.28
264
2128
1046
9489
1.14
3.25
2.7
2.6
0.00
0.06
1.31
11
148
144
1063
1.37
3.22
5.4
4.0
1.38
1.27
mg/l
1.13
136
996
683
6013
1.17
3.22
2.7
2.6
6.51
6.11
e6/l
0.26
637
5469
28
136
2.07
3.21
3.0
2.3
513.35
505.92
min
0.16
20
106
286
2320
1.25
3.21
2.1
2.1
6.00
6.13
ph
1.32
156
1375
7
11
6.37
3.18
1.0
1.7
—
—
—
0
0
11
29
3.80
3.18
1.2
1.2
—
—
—
0
0
27
130
2.08
3.17
2.3
2.3
27.56
30.75
%
0.58
27
130
1499
13932
1.13
3.16
2.8
2.6
—
—
estimate
—
0
0
314
2579
1.24
3.15
2.9
2.9
1.67
1.74
%
0.68
274
2349
260
2091
1.26
3.14
1.3
1.2
—
—
—
0
0
145
1078
1.36
3.12
1.0
1.1
—
—
—
0
0
990
8978
1.14
3.07
3.5
3.0
26.28
82.66
e6/l
2.47
753
6696
15
56
2.69
3.05
1.7
2.8
—
—
—
0
0
127
929
1.38
3.03
2.4
2.5
9.75
10.94
mg/l
1.09
115
886
48
285
1.69
3.01
2.6
2.8
242.18
234.66
e6/l
0.09
38
236
46
270
1.71
3.01
2.6
2.4
1.29
1.35
g/24h
0.05
30
179
44
255
1.73
3.01
1.1
1.1
1.04
1.05
ratio
0.25
34
205
1014
9225
1.14
2.98
4.3
3.6
8.24
8.53
mmol/l
1.02
847
8199
399
3379
1.20
2.97
1.4
1.4
23.90
21.33
iu/l
0.81
331
2901
144
1079
1.35
2.96
1.0
1.1
—
—
—
0
0
3127
30458
1.16
2.95
4.0
3.7
1.34
1.31
mmol/l
1.52
2952
29121
233
1869
1.26
2.90
2.8
3.0
70.03
71.92
e9/l
0.31
168
1325
3313
32437
1.19
2.84
5.0
4.7
2.86
2.89
mmol/l
1.06
3125
31138
219
1754
1.26
2.77
2.7
2.5
66.53
67.46
g/l
0.99
207
1657
49
300
1.64
2.77
1.2
1.4
1.83
1.91
mmol/l
0.36
43
286
19
84
2.27
2.77
1.2
1.2
—
—
—
0
0
422
3617
1.19
2.76
2.9
2.7
6.90
7.21
umol/l
0.13
356
3146
155
1188
1.32
2.75
1.1
1.1
—
—
—
0
0
61
395
1.55
2.74
3.2
4.2
362.85
1002.74
u/ml
0.47
52
371
85
592
1.45
2.71
1.7
1.5
—
—
—
0
0
19
85
2.24
2.70
1.3
1.2
—
—
—
0
0
19
85
2.24
2.70
1.3
1.2
—
—
—
0
0
19
85
2.24
2.70
1.3
1.2
—
—
—
0
0
227
1835
1.25
2.67
5.3
4.2
101.80
83.36
ng/l
1.08
205
1667
26
133
1.96
2.64
3.0
2.3
0.30
0.20
e9/l
0.24
11
61
42
251
1.68
2.61
3.2
3.2
52.54
55.74
%
0.40
37
226
173
1362
1.28
2.54
2.3
2.2
—
—
—
0
0
6
11
5.46
2.54
1.0
1.7
—
—
—
0
0
413
3562
1.18
2.52
2.7
2.5
13.62
13.70
nmol/l
0.08
386
3338
644
7187
0.87
2.49
3.4
3.4
1.02
1.24
kg/l
0.50
421
4591
45
278
1.63
2.49
2.7
2.8
597.85
551.27
e6/l
0.21
34
222
194
1554
1.26
2.49
1.3
1.3
—
—
—
0
0
97
706
1.38
2.45
4.5
2.9
8.70
8.77
kpa
0.16
92
693
35
203
1.73
2.44
1.0
1.1
—
—
—
0
0
68
464
1.47
2.43
3.2
3.8
—
—
—
0
0
111
827
1.35
2.43
2.1
2.0
1.61
1.71
ug/l
0.06
95
748
361
3091
1.19
2.41
1.2
1.2
—
—
—
0
0
100
734
1.37
2.40
2.7
2.7
1.84
2.10
index
0.19
62
404
842
7666
1.13
2.40
1.8
1.7
—
—
—
0
0
39
235
1.67
2.38
4.9
3.7
—
—
—
0
0
37
221
1.68
2.34
3.1
3.4
1135.46
1059.00
u/ml
0.07
37
221
16
71
2.26
2.34
1.1
1.6
—
—
—
0
0
23
119
1.94
2.30
1.1
1.1
—
—
—
0
0
288
2428
1.20
2.30
1.4
1.3
47.74
40.76
au/ml
0.17
15
164
306
2598
1.19
2.26
2.6
2.4
14.21
19.29
au/ml
1.76
44
395
78
557
1.41
2.23
2.4
2.5
12.16
29.81
iu/ml
—
9
37
226
2718
0.82
2.21
1.7
1.6
—
—
—
0
0
162
1293
1.26
2.18
2.0
2.2
19.96
20.45
s
1.10
138
1108
65
921
0.70
2.17
9.4
8.5
—
—
—
0
0
27
152
1.78
2.11
1.7
1.6
—
—
—
0
0
153
1219
1.27
2.10
1.1
1.1
4.24
2.48
u/ml
0.57
85
636
178
1444
1.24
2.09
1.3
1.3
0.18
1.10
u/ml
—
8
112
24
132
1.82
2.03
1.4
1.6
75.43
106.13
nmol/24h
1.52
24
132
128
1004
1.28
2.00
2.5
2.9
3.60
3.52
g/l
0.24
121
953
346
3008
1.17
1.96
1.2
1.2
151.31
136.95
u/ml
0.33
139
1197
206
1712
1.22
1.95
1.5
1.4
8.66
8.32
u/l
0.14
159
1384
43
281
1.54
1.94
1.9
2.1
0.88
0.90
%
0.14
32
190
601
5433
1.13
1.93
1.8
1.7
—
—
—
0
0
29
172
1.69
1.92
1.1
1.0
6.80
13.10
u/ml
1.67
22
123
22
120
1.84
1.92
1.0
1.0
—
—
—
0
0
27
157
1.72
1.92
2.0
1.7
—
—
—
0
0
444
3942
1.14
1.89
2.1
2.3
29.46
29.38
s
0.09
435
3825
127
1006
1.27
1.86
1.7
1.8
—
—
—
0
0
34
213
1.60
1.85
3.4
3.0
19.82
14.17
index
0.69
22
151
179
1476
1.22
1.84
1.5
1.7
8.52
11.05
u/ml
0.52
42
464
236
1999
1.19
1.84
1.1
1.1
274.00
193.00
titre
—
5
60
27
160
1.69
1.81
1.6
1.4
—
—
—
0
0
85
641
1.33
1.80
1.8
2.2
—
—
—
0
0
9
35
2.58
1.80
1.1
1.0
117.33
96.00
titre
—
9
35
490
4397
1.13
1.78
3.3
2.7
3.45
3.14
e6/l
0.20
228
1979
496
5508
0.89
1.78
1.3
1.3
—
—
—
0
0
71
524
1.36
1.73
1.2
1.2
—
—
—
0
0
24
397
0.60
1.72
31.6
20.4
1474.46
3773.57
nmol/l
0.47
24
383
29
178
1.63
1.72
3.2
2.3
12.17
9.25
%
0.39
29
172
8
30
2.67
1.72
1.4
1.1
—
—
—
0
0
7
24
2.92
1.72
2.7
3.3
—
—
—
0
0
90
690
1.31
1.71
1.3
1.2
—
—
—
0
0
19
103
1.85
1.71
1.4
1.2
15.47
12.10
u/l
0.53
19
94
15
282
0.53
1.70
4.3
2.4
10.07
10.45
mmol/l
0.31
15
276
18
96
1.88
1.70
1.0
1.1
—
—
—
0
0
18
96
1.88
1.70
1.0
1.1
—
—
—
0
0
18
96
1.88
1.70
1.0
1.1
—
—
—
0
0
148
1208
1.23
1.70
2.4
2.2
—
—
—
0
0
189
1584
1.20
1.68
1.8
1.7
—
—
—
0
0
23
381
0.60
1.67
22.7
14.8
854.52
4212.26
nmol/l
0.49
23
368
1026
9610
1.09
1.66
2.1
2.1
—
—
—
0
0
10
40
2.50
1.66
1.4
1.4
5.67
5.85
mmol/l
—
10
40
292
2548
1.16
1.62
1.1
1.1
—
—
—
0
0
49
344
1.43
1.61
1.5
1.7
1.44
1.34
promille
0.17
36
272
69
514
1.35
1.61
1.1
1.1
1.42
1.46
g/l
0.42
63
471
41
278
1.48
1.61
4.2
5.3
11.36
7.10
mmol/l
0.66
34
238
190
2245
0.84
1.60
1.1
1.1
0.64
0.67
ratio
0.22
19
200
259
2242
1.17
1.59
10.4
9.6
—
—
—
0
0
31
198
1.57
1.59
1.6
1.9
5.63
3.36
mg/l
0.86
31
190
34
222
1.54
1.59
1.5
1.3
79.18
77.41
umol/l
0.15
34
222
110
877
1.26
1.57
1.8
2.4
429.94
344.12
ug/l
0.17
101
823
2893
28321
1.10
1.56
16.4
15.2
13.36
13.34
%
0.45
2858
27993
89
692
1.29
1.56
1.2
1.1
—
—
—
0
0
28
176
1.60
1.54
2.3
1.7
1.68
1.28
nmol/l
0.64
20
135
5
15
3.34
1.52
1.0
1.0
—
—
—
0
0
5
15
3.34
1.52
1.0
1.0
—
—
—
0
0
5
15
3.34
1.52
1.0
1.0
—
—
—
0
0
5
15
3.34
1.52
1.0
1.0
—
—
—
0
0
5
15
3.34
1.52
1.0
1.0
—
—
—
0
0
77
589
1.31
1.52
3.2
3.4
38.02
50.37
mg/l
0.55
60
498
7
27
2.60
1.51
2.9
3.2
—
—
—
0
0
77
590
1.31
1.51
3.2
3.4
35.50
44.28
mg/l
0.33
60
499
24
147
1.64
1.47
1.1
1.1
—
—
—
0
0
260
2268
1.16
1.47
8.3
8.4
1.21
1.30
mmol/l
1.03
252
2226
279
2449
1.15
1.45
4.5
4.2
1.64
1.78
mmol/l
0.36
241
2130
1045
9851
1.08
1.44
1.6
1.6
—
—
—
0
0
39
269
1.45
1.44
1.5
1.2
114.38
116.17
pmol/l
0.10
39
269
60
447
1.35
1.43
1.2
1.7
75.75
83.31
mu/l
0.10
51
408
131
1080
1.22
1.42
1.1
1.1
3.16
2.02
u/ml
0.32
63
552
56
415
1.35
1.39
1.2
1.5
298.53
359.78
pmol/l
0.84
46
363
52
382
1.37
1.36
1.4
1.3
0.16
0.22
nmol/l
0.55
43
288
108
877
1.24
1.36
1.1
1.1
3.35
4.84
u/ml
0.56
51
392
203
1751
1.17
1.35
1.1
1.1
—
—
—
0
0
114
933
1.23
1.34
1.1
1.1
3.78
3.92
u/ml
0.03
57
475
43
308
1.40
1.32
1.1
1.1
—
—
—
0
0
45
326
1.39
1.30
1.0
1.1
284.85
277.24
mg/l
0.32
40
302
68
526
1.30
1.28
3.3
3.2
1.33
1.82
ratio
1.24
36
290
105
857
1.23
1.28
1.6
1.5
—
—
—
0
0
38
268
1.42
1.27
1.0
1.0
—
—
—
0
0
40
285
1.41
1.27
1.1
1.1
—
—
—
0
0
87
696
1.26
1.26
1.1
1.2
—
—
—
0
0
745
6967
1.09
1.25
3.9
3.5
2.00
1.57
ug/l
0.73
660
6429
6
25
2.40
1.24
3.2
2.0
—
—
—
0
0
10
49
2.04
1.22
1.4
1.3
25.86
23.15
ng/l
—
5
32
101
828
1.23
1.19
1.1
1.1
23.38
14.25
au/ml
0.40
19
282
56
428
1.31
1.17
2.3
2.8
7.01
7.36
mmol/l
0.41
56
417
688
6432
1.09
1.17
1.5
1.5
—
—
—
0
0
10
50
2.00
1.16
1.2
1.0
—
—
—
0
0
73
579
1.27
1.16
2.7
2.1
133.93
134.01
g/l
0.01
60
463
25
166
1.51
1.14
1.2
1.2
—
—
—
0
0
43
317
1.36
1.14
1.5
1.6
284.06
283.15
mosm/kgh2o
0.11
33
237
12
65
1.85
1.13
2.7
2.4
—
—
—
0
0
26
175
1.49
1.12
1.7
1.4
1376.65
2377.18
e6/l
1.36
20
112
12
208
0.58
1.11
1.0
1.1
—
—
—
0
0
26
176
1.48
1.10
1.5
2.2
—
—
—
0
0
15
244
0.61
1.09
1.9
3.0
41.08
44.47
%
—
8
129
196
1719
1.15
1.09
1.4
1.3
202.92
227.56
miu/ml
0.53
97
826
104
866
1.21
1.08
1.2
1.2
33.80
34.06
u/ml
—
6
71
80
649
1.24
1.07
1.3
1.2
4.59
3.77
u/ml
0.33
34
307
131
1117
1.18
1.05
1.0
1.1
1.45
3.74
eliau/ml
2.22
20
179
7
33
2.12
1.05
2.1
3.4
—
—
—
0
0
23
154
1.50
1.03
1.7
1.4
33678.80
30552.51
e6/l
0.07
15
82
283
2552
1.12
1.03
4.6
4.1
7.37
7.38
ph
0.43
179
1419
7
34
2.06
1.02
1.1
1.2
—
57.90
—
0
5
94
782
1.21
1.00
1.4
1.5
—
—
—
0
0
7
35
2.00
1.00
1.4
2.1
—
—
—
0
0
11
61
1.81
0.98
1.1
1.0
—
—
—
0
0
5
23
2.18
0.98
3.6
1.9
—
—
—
0
0
36
266
1.36
0.97
1.1
1.2
—
—
—
0
0
96
803
1.20
0.97
1.6
1.5
149.32
146.32
au/ml
0.09
28
235
9
50
1.80
0.96
1.1
1.4
3.11
2.81
%
—
9
41
513
4783
1.08
0.95
3.3
2.6
0.82
1.08
e6/l
0.63
254
2378
124
1064
1.17
0.95
1.0
1.1
0.74
1.19
u/ml
0.68
58
493
97
1143
0.84
0.90
1.3
1.3
—
—
—
0
0
119
1025
1.17
0.88
2.1
2.2
4.27
4.00
iu/l
0.11
50
436
455
4237
1.08
0.88
2.6
2.4
0.66
0.63
ug/l
0.25
214
1918
129
1119
1.16
0.88
1.1
1.1
7.70
6.00
u/ml
0.46
79
654
10
56
1.79
0.87
1.1
1.2
—
—
—
0
0
35
264
1.33
0.86
1.0
1.1
1585.29
1527.77
miu/ml
0.11
35
264
36
273
1.32
0.85
2.2
3.1
0.81
0.70
e9/l
0.54
36
267
30
221
1.36
0.85
1.8
1.6
5.90
6.52
mmol/l
0.95
22
162
18
120
1.50
0.85
1.0
1.1
—
—
—
0
0
110
946
1.17
0.84
1.2
1.4
475.96
482.06
mg/l
0.05
102
912
95
808
1.18
0.83
1.0
1.1
—
—
—
0
0
50
398
1.26
0.83
1.2
1.5
61.06
66.98
mmol/l
0.31
33
329
95
809
1.18
0.83
1.1
1.1
0.14
0.47
u/ml
0.81
30
248
75
625
1.20
0.82
1.2
1.2
—
—
—
0
0
49
390
1.26
0.82
1.1
1.2
37.40
38.15
mg/l
0.05
41
325
82
690
1.19
0.82
3.4
3.2
0.87
0.84
nmol/l
0.10
71
613
13
81
1.61
0.81
1.3
1.7
—
—
—
0
0
35
267
1.31
0.80
1.1
1.1
—
—
—
0
0
6
33
1.82
0.79
1.0
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.0
—
0.03
—
0
10
82
695
1.18
0.77
2.4
2.1
9.64
10.26
g/l
0.88
75
643
23
314
0.73
0.76
1.4
3.0
—
—
—
0
0
47
379
1.24
0.73
1.0
1.1
264.69
234.19
mg/l
0.52
39
337
35
272
1.29
0.72
1.9
1.7
50.48
53.51
%
0.18
25
174
9
57
1.58
0.71
1.2
1.4
—
—
—
0
0
96
833
1.16
0.69
1.3
1.4
16.45
22.10
u/l
1.50
77
693
38
301
1.27
0.69
1.9
2.1
32.95
32.43
pg
0.27
38
301
41
328
1.25
0.69
1.0
1.1
11.36
8.01
iu/ml
—
10
103
13
85
1.53
0.69
1.2
1.4
—
—
—
0
0
12
77
1.56
0.68
1.0
1.1
—
—
—
0
0
108
950
1.14
0.66
1.6
1.4
0.57
0.45
nmol/l
0.22
81
777
31
241
1.29
0.65
1.2
1.2
—
—
—
0
0
11
70
1.57
0.65
1.4
2.3
1.93
2.88
mmol/l
0.95
11
63
105
924
1.14
0.64
1.3
1.3
261.90
249.93
u/ml
0.15
73
603
203
2216
0.91
0.64
3.3
2.4
—
—
—
0
0
469
4436
1.07
0.63
1.6
1.6
3.45
3.56
mmol/l
1.43
306
2974
20
146
1.37
0.63
1.0
1.1
—
—
—
0
0
23
172
1.34
0.63
1.0
1.1
—
—
—
0
0
42
342
1.23
0.62
1.1
1.1
—
—
—
0
0
55
462
1.19
0.61
2.5
2.3
—
—
—
0
0
254
2355
1.08
0.60
2.4
2.4
2858.14
5253.94
u/l
1.05
94
875
0
21
0.00
0.60
0.0
2.0
—
287.81
—
0
21
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
27
210
1.29
0.58
3.1
3.2
0.75
0.83
nmol/l
0.46
18
168
8
53
1.51
0.58
2.0
1.6
—
—
—
0
0
262
2813
0.93
0.57
2.3
2.2
—
—
—
0
0
511
4866
1.06
0.57
2.7
2.6
2.41
2.42
mmol/l
0.17
451
4363
74
643
1.15
0.56
1.4
1.6
300.07
367.00
mu/l
1.87
60
526
271
2529
1.08
0.56
4.7
4.1
5.73
5.84
kpa
1.15
266
2463
5
89
0.56
0.56
1.6
1.2
—
—
—
0
0
280
2617
1.08
0.55
9.1
8.9
0.82
0.87
mmol/l
0.08
244
2162
20
150
1.34
0.55
1.9
1.4
—
—
—
0
0
6
37
1.62
0.55
1.0
1.1
0.05
0.02
u/ml
—
6
37
10
65
1.54
0.55
5.8
3.8
33.80
15.60
mg/mmol
—
10
56
247
2651
0.93
0.55
3.1
2.3
—
—
—
0
0
9
60
1.50
0.54
2.0
1.3
—
—
—
0
0
219
2030
1.08
0.54
4.1
4.4
10.58
36.54
ug/l
0.82
151
1551
322
3029
1.07
0.54
2.8
2.8
38.45
38.93
u/l
0.04
279
2623
121
1091
1.11
0.53
1.4
1.3
164.17
87.17
titre
0.76
12
120
394
3735
1.06
0.52
1.5
1.6
—
—
—
0
0
103
922
1.12
0.52
1.2
1.1
—
—
—
0
0
281
2638
1.07
0.51
9.0
8.9
5.15
5.10
kpa
0.39
270
2548
19
144
1.32
0.50
4.1
4.9
—
—
—
0
0
281
2639
1.07
0.50
9.0
8.8
12.91
13.12
kpa
0.28
272
2551
80
707
1.13
0.50
1.1
1.1
—
—
—
0
0
23
181
1.27
0.48
1.4
1.4
131.37
134.79
nmol/l
0.21
23
181
24
190
1.26
0.48
1.2
1.3
—
—
—
0
0
26
208
1.25
0.47
2.5
2.7
—
—
—
0
0
61
531
1.15
0.47
2.4
2.6
1.43
1.46
mmol/l
0.11
61
515
8
121
0.66
0.45
2.1
2.5
22.21
16.72
umol/l
—
8
121
44
375
1.18
0.45
2.0
1.7
—
—
—
0
0
18
231
0.78
0.44
8.9
6.8
10.89
8.24
%
1.52
18
231
18
231
0.78
0.44
4.4
3.4
39.83
43.90
%
0.33
18
231
576
5547
1.05
0.44
1.9
1.8
—
—
—
0
0
603
5814
1.04
0.44
1.9
1.8
3.64
3.66
ratio
0.10
446
4372
517
4969
1.05
0.43
3.7
3.4
610.47
428.12
ng/l
0.26
320
3105
279
2637
1.06
0.43
9.3
9.0
7.42
7.42
ph
0.51
138
1443
9
129
0.70
0.43
1.6
2.0
10.64
8.22
mmol/l
—
9
129
205
1918
1.07
0.43
2.0
1.8
0.29
0.31
mg/l
0.29
109
970
35
294
1.19
0.42
1.0
1.1
—
—
—
0
0
92
831
1.11
0.42
1.1
1.3
3.51
3.63
mmol/l
0.97
85
791
0
15
0.00
0.41
0.0
1.1
—
0.04
—
0
7
41
352
1.17
0.40
1.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
164
1756
0.93
0.38
1.4
1.4
—
—
—
0
0
11
148
0.74
0.38
1.0
1.4
—
—
—
0
0
32
270
1.19
0.38
1.0
1.2
—
—
—
0
0
18
225
0.80
0.38
1.7
1.4
37044.20
101109.25
e6/l
—
10
162
109
1184
0.92
0.37
4.8
3.2
—
—
—
0
0
9
71
1.27
0.36
1.2
1.1
—
—
—
0
0
13
99
1.31
0.35
3.1
2.7
0.61
0.61
mmol/l
0.03
13
99
17
135
1.26
0.35
1.4
1.5
0.59
0.52
e9/l
0.59
17
135
70
632
1.11
0.35
1.2
1.1
16274.91
1359.96
iu/ml
0.43
16
160
32
274
1.17
0.33
1.4
1.4
—
—
—
0
0
272
2850
0.95
0.33
3.2
2.3
—
—
—
0
0
6
46
1.30
0.33
1.0
1.3
37.67
32.20
%
—
6
41
33
380
0.87
0.31
4.5
5.0
33.97
112.41
u/ml
—
10
119
7
97
0.72
0.30
1.0
1.1
4.57
6.19
u/ml
—
7
97
113
1212
0.93
0.30
1.4
1.4
—
—
—
0
0
927
9083
1.03
0.29
6.0
6.4
—
—
—
0
0
29
250
1.16
0.29
1.2
1.1
—
—
—
0
0
50
450
1.11
0.28
1.2
1.3
—
55.95
—
0
25
57
627
0.91
0.28
1.5
1.7
6893.68
10630.92
e6/l
1.09
41
447
41
365
1.12
0.27
1.1
1.1
0.61
1.02
u/ml
0.54
14
84
273
2841
0.96
0.27
2.9
2.2
—
—
—
0
0
10
127
0.79
0.25
1.1
1.9
—
—
—
0
0
75
694
1.08
0.25
1.0
1.1
3.05
3.03
eliau/ml
0.00
36
380
160
1680
0.95
0.24
1.9
2.2
6.47
6.92
ug/l
0.13
136
1508
6
81
0.74
0.24
5.2
3.0
—
—
—
0
0
272
2818
0.96
0.23
3.0
2.3
—
—
—
0
0
36
401
0.90
0.23
1.6
1.7
—
—
—
0
0
59
543
1.09
0.23
3.1
2.5
82.63
139.70
ug/min
0.73
34
351
31
275
1.13
0.23
1.2
1.2
—
—
—
0
0
5
40
1.25
0.22
1.6
3.4
31.60
47.53
umol/l
—
5
32
23
200
1.15
0.22
1.8
1.7
1306.67
2853.33
titre
—
9
27
20
172
1.16
0.22
1.2
1.4
180.25
169.97
mmol/24h
0.28
20
172
13
107
1.22
0.21
1.1
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
3.1
—
14.00
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.31
—
0
10
40
363
1.10
0.21
1.1
1.1
0.36
2.06
u/ml
1.23
14
117
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
64
595
1.08
0.20
3.6
3.3
37.93
34.76
umol/l
0.44
54
554
114
1200
0.95
0.20
1.3
1.4
1.25
1.28
mm
0.14
71
826
9
114
0.79
0.20
1.0
1.0
33.29
37.54
iu/ml
—
9
114
23
203
1.13
0.19
1.3
1.2
—
—
—
0
0
40
366
1.09
0.19
1.5
1.8
—
—
—
0
0
37
404
0.91
0.18
1.4
1.3
180.07
200.41
pmol/l
0.32
37
404
33
300
1.10
0.17
1.7
1.2
140.00
233.82
titre
—
5
55
7
61
1.15
0.17
1.0
1.2
4.20
5.69
nmol/l
—
7
56
11
130
0.85
0.16
1.0
2.0
84.45
86.77
ng/l
0.05
11
130
6
76
0.79
0.15
1.0
1.9
—
—
—
0
0
120
1249
0.96
0.15
1.4
1.5
—
—
—
0
0
12
140
0.86
0.15
2.8
3.1
—
—
—
0
0
70
737
0.95
0.14
1.7
1.8
—
—
—
0
0
44
411
1.07
0.14
1.2
1.1
20.18
16.39
u/ml
0.30
19
194
18
160
1.13
0.14
2.1
2.6
253.90
156.59
umol/l
—
10
80
8
97
0.82
0.13
2.3
2.2
—
—
—
0
0
81
775
1.05
0.13
1.2
1.3
2.82
2.95
ug/l
0.11
75
700
9
110
0.82
0.13
2.2
2.2
15.51
17.01
%
—
9
110
204
2091
0.97
0.12
2.5
2.3
0.21
0.43
e6/l
1.99
192
1975
155
1507
1.03
0.12
1.3
1.5
59.20
60.98
ug/l
0.16
118
1196
167
1715
0.97
0.11
2.1
2.7
42.26
46.16
u/ml
0.12
159
1664
18
199
0.90
0.11
2.0
2.6
11.34
9.55
mg/l
0.94
12
169
82
789
1.04
0.11
4.0
3.8
631.20
470.00
u/ml
0.14
70
684
10
86
1.16
0.11
1.0
1.7
39.69
42.25
g/l
—
10
86
47
495
0.95
0.10
1.4
1.4
6.85
6.96
mmol/l
0.09
40
454
13
115
1.13
0.10
1.2
1.1
—
—
—
0
0
190
1942
0.98
0.10
5.0
3.4
—
—
—
0
0
58
555
1.05
0.10
3.3
3.0
22.47
25.03
mg/l
0.26
44
372
85
821
1.04
0.10
1.4
1.5
12.06
25.95
e6/l
1.04
64
607
20
217
0.92
0.09
2.1
1.6
24.17
35.47
%
0.68
12
138
22
237
0.93
0.09
2.0
1.6
—
—
—
0
0
260
2559
1.02
0.08
1.5
1.5
1041.11
1030.86
mu/l
0.06
199
2011
5
62
0.81
0.08
4.4
1.8
1.12
1.19
mmol/l
—
5
57
32
303
1.06
0.07
1.3
1.2
0.55
0.68
ratio
1.43
20
167
6
70
0.86
0.07
1.8
1.9
1.68
1.50
mg/l
—
6
60
10
112
0.89
0.07
2.0
2.2
—
—
—
0
0
7
84
0.83
0.07
1.1
1.2
—
—
—
0
0
14
128
1.09
0.06
1.4
1.5
12.94
14.73
pmol/l
0.88
14
109
36
376
0.96
0.06
1.4
1.6
—
—
—
0
0
36
376
0.96
0.06
1.4
1.6
—
—
—
0
0
36
376
0.96
0.06
1.4
1.6
—
—
—
0
0
36
376
0.96
0.06
1.4
1.6
—
—
—
0
0
10
111
0.90
0.06
1.7
1.6
8.78
8.52
ug/l
—
10
111
57
553
1.03
0.05
6.1
7.1
377.14
377.16
umol/l
0.00
44
496
23
243
0.95
0.05
1.1
1.1
7.74
7.62
mm/h
0.03
23
243
76
742
1.02
0.05
1.4
1.3
—
—
—
0
0
19
202
0.94
0.05
7.2
8.0
2.21
83.12
ug/l
—
10
150
47
455
1.03
0.05
1.2
1.2
17.42
29.53
u/l
0.71
40
388
118
1160
1.02
0.05
1.3
1.3
—
—
—
0
0
144
1419
1.02
0.05
1.3
1.4
—
—
—
0
0
32
333
0.96
0.05
1.2
2.2
—
2185.15
pmol/l
—
0
51
26
249
1.04
0.04
3.7
2.5
24.79
26.76
mg/l
0.14
19
174
37
358
1.03
0.04
1.1
1.0
0.30
1.33
u/ml
—
8
76
18
171
1.05
0.03
1.4
1.2
920.00
963.64
titre
—
5
33
151
1498
1.01
0.02
2.5
2.8
142.00
133.61
ng/l
0.10
135
1313
12
113
1.06
0.01
1.7
1.5
2.40
3.76
%
—
5
29
85
841
1.01
0.01
1.4
1.5
257.42
2090.14
e6/l
1.39
66
664
10
94
1.06
0.01
2.8
1.9
—
—
—
0
0
13
131
0.99
0.00
1.5
1.2
28.62
28.54
s
0.02
13
131
21
209
1.00
0.00
2.4
3.0
52.80
101.47
au/ml
—
5
29
24
236
1.02
0.00
1.0
1.0
—
—
—
0
0
76
757
1.00
0.00
1.1
1.1
—
—
—
0
0
12
117
1.03
0.00
1.0
1.3
—
—
—
0
0
25
253
0.99
0.00
2.8
1.8
3.59
2.56
u/ml
—
7
74
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
145.14
—
0
7
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
4.46
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
290.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
-0.00
1.4
1.4
11.37
8.79
mmol/l
—
9
91
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
65.98
—
0
6
143
1430
1.00
-0.00
1.4
1.4
1.17
1.15
ratio
0.08
78
860
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.3
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.3
—
0.45
—
0
6

Mortality – FinRegistry

↥

Association

Association between endpoint H8_EUSTSALP and mortality.

Females

Parameter HR [95% CI] p-value
H8_EUSTSALP 0.882 [0.71, 1.09] 0.255
Birth year 0.993 [0.98, 1.0] 0.125

During the follow-up period (1.1.1998 — 31.12.2019), 109 out of 3289 females with H8_EUSTSALP died.

Males

Parameter HR [95% CI] p-value
H8_EUSTSALP 0.873 [0.69, 1.1] 0.243
Birth year 0.99 [0.98, 1.0] 0.032

During the follow-up period (1.1.1998 — 31.12.2019), 112 out of 2993 males with H8_EUSTSALP died.

Mortality risk

Mortality risk for people of age

years, who have H8_EUSTSALP.

N-year risk Females Males
1 0.092% 0.177%
5 0.469% 1.006%
10 1.221% 2.684%
15 2.401% 5.315%
20 4.328% 9.138%

Relationships between endpoints

↥

Index endpoint: H8_EUSTSALP – Eustachian salpingitis and obstruction

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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