Chronic suppurative otitis media

H8_CHRON_SUPOTITIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H66.1, H66.2, H66.3
  • Hospital discharge: ICD-9 3821
  • Hospital discharge: ICD-8 3811
  • Cause of death: ICD-10 H66.1, H66.2, H66.3
  • Cause of death: ICD-9 3821

2 out of 7 registries used, show all original rules.

3130

4. Check minimum number of events

None

3130

5. Include endpoints

None

3130

6. Filter based on genotype QC (FinnGen only)

2792

Control definitions (FinnGen only)

Control exclude
H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 36319 15843 20247
Only index persons 29488 13262 16226
Unadjusted period prevalence (%)
Whole population 0.51 0.45 0.57
Only index persons 0.56 0.49 0.62
Median age at first event (years)
Whole population 11.18 15.82 7.08
Only index persons 10.85 15.70 6.89

-FinnGen-

Key figures

All Female Male
Number of individuals 2792 1408 1384
Unadjusted period prevalence (%) 0.57 0.50 0.63
Median age at first event (years) 29.52 26.16 32.95

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2900
Matched controls
28990
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
48.1
323.0
189
42
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
280.5
307.7
490
21
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
359.3
307.7
429
14
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
307.7
515
*
DC1AD
NOMESCO Finland
Temporalbone CT
59.4
307.7
189
34
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
41.0
307.7
213
56
H71
ICD-10 Finland
Cholesteatoma of middle ear
4168.6
307.7
376
*
H65.2
ICD-10 Finland
Chronic serous otitis media
154.5
307.7
228
16
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
28.0
307.7
327
131
H66.9
ICD-10 Finland
Otitis media, unspecified
8.3
307.7
548
795
UDC00
NOMESCO Finland
Ear microscopy
8.4
307.7
614
900
H66.0
ICD-10 Finland
Acute suppurative otitis media
10.0
307.7
702
899
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
1213.9
307.7
503
5
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
718.5
307.7
665
12
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
307.7
1391
*
4122
FHL
Tympanostomy (tympanic tube)
134.1
307.7
200
16
H65.3
ICD-10 Finland
Chronic mucoid otitis media
264.7
307.7
448
20
EMB30
NOMESCO Finland
Adenotomy
13.4
263.0
256
208
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.3
242.7
781
2269
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
37.0
226.2
141
40
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
31.8
187.3
122
40
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
4.8
186.7
474
1130
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
183.3
174
*
H60.3
ICD-10 Finland
Other infective otitis externa
10.0
182.9
215
230
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
10.5
180.5
205
209
H65.0
ICD-10 Finland
Acute serous otitis media
15.3
177.6
158
109
S02CA02
ATC
flumetasone and antiinfectives; otic
5.8
173.6
341
648
DFF00
NOMESCO Finland
Pure tone audiometry
4.2
172.7
531
1464
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
15.6
170.8
150
101
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
160.9
153
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.8
151.4
1131
5336
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
16.6
148.8
126
79
4141
FHL
Myringoplasty (also for reasons other than inflammation)
502.3
145.8
144
*
DCD00
NOMESCO Finland
Myringoplasty
1461.6
142.9
138
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
4.1
135.2
413
1123
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
132.3
126
*
H60.8
ICD-10 Finland
Other otitis externa
6.7
130.7
215
341
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
129.1
123
*
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
+∞
119.6
114
*
TDA90
NOMESCO Finland
Removal wax from ear
11.9
118.6
122
107
4451
FHL
Guitar cutting
8.1
115.3
159
207
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
15.6
111.3
97
64
Z97.4
ICD-10 Finland
Presence of external hearing-aid
4.7
110.8
273
626
H66.2
ICD-10 Finland
Chronic atticoantral suppurative otitis media
+∞
108.0
103
*
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
22.6
104.9
77
35
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
5.2
104.1
224
458
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
1044.6
103.9
101
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.7
100.9
669
2881
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
43.7
100.5
60
14
H74.1
ICD-10 Finland
Adhesive middle ear disease
958.9
95.5
93
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.2
94.1
1703
11287
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
43.9
93.9
56
13
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
93.2
89
*
J35.2
ICD-10 Finland
Hypertrophy of adenoids
7.0
92.3
144
215
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
+∞
89.0
85
*
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.7
88.4
304
889
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
440.4
86.5
86
*
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
85.8
82
*
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
78.5
75
*
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
78.5
75
*
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
387.3
76.1
76
*
H04
ICPC
Ear discharge
4.6
75.4
186
425
1450
FHL
Otomicroscopy
24.5
74.6
53
22
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
158.1
73.3
77
5
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
9.0
67.5
84
96
J01DA08
ATC
[U] cefaclor
2.6
67.0
437
1837
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
66.9
64
*
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
3.6
66.7
236
700
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
65.9
63
*
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
65.9
63
*
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
5.3
65.8
137
271
H92.1
ICD-10 Finland
Otorrhoea
31.2
65.6
43
14
R5120
NOMESCO Finland
Preparation of an aid
4.6
64.4
159
363
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
+∞
61.7
59
*
J35.8
ICD-10 Finland
Other chronic diseases of tonsils and adenoids
12.8
60.7
59
47
H66
ICD-10 Finland
Suppurative and unspecified otitis media
4.7
59.8
143
318
H61.2
ICD-10 Finland
Impacted cerumen
3.0
59.2
278
979
J01DA06
ATC
[U] cefuroxime
2.4
58.7
467
2145
J01DA01
ATC
[U] cefalexin
1.8
53.8
1747
13081
DFF15
NOMESCO Finland
Speech audiometry
3.4
53.4
200
614
DCD10
NOMESCO Finland
Tympanoplasty
186.7
53.1
55
*
4151
FHL
Reoperation for chronic otitis media
516.8
51.6
51
*
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
51.2
49
*
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
506.4
50.6
50
*
S02AA03
ATC
boric acid; otic
8.7
49.5
63
74
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
11.5
49.2
51
45
H01
ICPC
Ear pain/earache
2.3
49.0
434
2078
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
475.3
47.4
47
*
R01AD08
ATC
fluticasone; nasal
1.9
46.9
823
5048
J01MA02
ATC
ciprofloxacin; systemic
1.8
46.6
1105
7428
H92.0
ICD-10 Finland
Otalgia
2.9
46.5
239
882
DGW00
NOMESCO Finland
Dilatation of eustachian tube
+∞
45.9
44
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
45.2
304
1286
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.7
44.5
144
401
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
10.2
44.3
50
50
RK520, ,
NOMESCO Finland
13.5
42.5
40
30
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
7.6
42.5
60
80
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.6
41.7
250
999
H60
ICD-10 Finland
Otitis externa
2.9
41.5
203
729
DAX08
NOMESCO Finland
Fitting of hearing aid
2.8
40.0
208
772
DEB30
NOMESCO Finland
Radical mastoidectomy
207.8
39.9
41
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
39.9
396
1976
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
38.6
37
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.6
36.6
217
861
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
187.3
35.8
37
*
J01DC02
ATC
cefuroxime; systemic
2.9
34.7
173
627
H73.1
ICD-10 Finland
Chronic myringitis
+∞
34.4
33
*
J01CA04
ATC
amoxicillin; systemic
1.8
34.2
2362
20467
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.2
33.9
136
435
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.4
32.9
119
357
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
32.3
31
*
H02AB04
ATC
methylprednisolone; systemic
2.0
32.1
396
2132
H02AB06
ATC
prednisolone; systemic
1.6
31.6
1278
9601
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
31.0
315
1579
J01FA09
ATC
clarithromycin; systemic
1.7
30.0
816
5549
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
6.3
29.6
50
81
J01FA10
ATC
azithromycin; systemic
1.6
29.3
1573
12525
RK320, ,
NOMESCO Finland
6.7
28.9
46
70
ZXA10
NOMESCO Finland
Bilateral
1.8
28.8
505
3041
J01DA09
ATC
[U] cefadroxil
1.7
28.2
701
4646
H72
ICD-10 Finland
Perforation of tympanic membrane
55.6
28.2
33
6
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
9.3
27.4
33
36
R03AC02
ATC
salbutamol; inhalant
1.5
26.5
1488
11858
J01DB01
ATC
cefalexin; oral
1.7
26.4
2278
19970
J01FF01
ATC
clindamycin; systemic
1.6
26.2
701
4724
J32.4
ICD-10 Finland
Chronic pansinusitis
4.5
26.2
63
141
38400
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) acuta
+∞
26.1
25
*
H95.8
ICD-10 Finland
Other postprocedural disorders of ear and mastoid process
136.2
25.6
27
*
RK110, ,
NOMESCO Finland
6.3
25.3
42
67
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
4.4
25.1
63
146
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.5
24.6
161
669
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
24.6
538
3435
50499
ICD-8 Finland
Deflected nasal septum
4.2
24.3
64
154
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
24.2
214
1014
4111
FHL
Ear canal extension
+∞
24.0
23
*
3824A
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified suppurative otitis media
+∞
24.0
23
*
H02AB07
ATC
prednisone; oral
1.8
23.9
364
2092
R03BA05
ATC
fluticasone; inhalant
1.7
23.7
500
3158
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
23.5
101
337
R03CC02
ATC
salbutamol; systemic
2.1
23.3
235
1171
4741B
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PHARYNGICAE]
5.4
23.2
46
87
4742A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Adenoid vegetations
4.2
22.8
60
144
ZXA00
NOMESCO Finland
Right side
1.6
22.0
660
4543
4143
FHL
Atticotomy or atticoanthromy through the ear canal
+∞
21.9
21
*
4146
FHL
Radical cutting (bridge broken)
+∞
21.9
21
*
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
63.0
21.9
25
*
DCW99
NOMESCO Finland
Other operation on eardrum and middle ear
221.5
21.6
22
*
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.3
21.6
81
249
J35.1
ICD-10 Finland
Hypertrophy of tonsils
3.5
21.4
74
216
J01DC04
ATC
cefaclor; oral
4.3
21.3
54
126
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
2.9
21.3
102
362
H60.4
ICD-10 Finland
Cholesteatoma of external ear
19.0
21.2
32
17
R01AD09
ATC
mometasone; nasal
1.5
21.2
1156
9018
J01AA02
ATC
doxycycline; systemic
1.5
21.0
1961
16939
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
20.9
20
*
H29
ICPC
Ear symptom/complaint other
1.8
20.8
343
2015
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
211.4
20.6
21
*
H71
ICPC
Acute otitis media/myringitis
4.2
20.5
55
134
4221
FHL
Polyp removal from the nasal cavity, sinus puncture or irrigation, or biopsy under general anesthesia or operating room
6.2
20.2
34
55
H60.1
ICD-10 Finland
Cellulitis of external ear
4.4
20.1
50
115
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
19.5
502
3324
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.8
19.5
332
1969
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.3
19.1
141
619
R06AE07
ATC
cetirizine; oral
1.4
19.1
1144
9032
ZXD20
NOMESCO Finland
Day surgery
1.8
19.0
325
1927
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
19.0
667
4736
DEB00
NOMESCO Finland
Cortical mastoidectomy
100.7
18.6
20
*
49300
ICD-8 Finland
Asthma, bronchiale
3.2
18.5
74
237
ZXA05
NOMESCO Finland
Left side
1.5
17.6
599
4217
H61.8
ICD-10 Finland
Other specified disorders of external ear
4.6
17.5
41
90
RK420, ,
NOMESCO Finland
24.2
17.3
24
10
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
17.1
922
7106
S02CA03
ATC
hydrocortisone and antiinfectives; otic
31.6
17.0
22
7
R03BA02
ATC
budesonide; inhalant
1.6
16.9
458
3061
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
16.9
202
1070
H70.0
ICD-10 Finland
Acute mastoiditis
+∞
16.7
16
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
16.6
702
5159
H70
ICPC
Otitis externa
3.1
16.5
69
227
H73.0
ICD-10 Finland
Acute myringitis
6.8
16.1
25
37
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
15.9
356
2269
J01MA12
ATC
levofloxacin; systemic
1.6
15.9
455
3077
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
3.6
15.7
52
148
46699
ICD-8 Finland
Acute bronchitis and bronchiolitis
3.7
15.4
48
131
Z96.2
ICD-10 Finland
Presence of otological and audiological implants
38.2
15.4
19
5
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
15.3
496
3447
R03BB04
ATC
tiotropium bromide; inhalant
1.8
15.2
255
1501
4224
FHL
Endonasal anthrostomy
4.5
15.2
36
80
J33.8
ICD-10 Finland
Other polyp of sinus
3.1
15.1
63
207
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
15.1
619
4511
R03AC12
ATC
salmeterol; inhalant
2.2
15.0
123
565
4741A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PALATINAE]
6.3
15.0
25
40
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.5
15.0
616
4491
J47
ICD-10 Finland
Bronchiectasis
3.2
14.9
59
188
R4135
NOMESCO Finland
Rehabilitation for hearing problems
3.1
14.8
61
199
4222
FHL
Endonasal etmoidectomy
5.5
14.8
28
51
38299
ICD-8 Finland
Unspecified otitis media with mastoiditis
+∞
14.6
14
*
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
14.2
14.5
24
17
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.3
14.5
106
464
EMB10
NOMESCO Finland
Tonsillectomy
2.0
14.3
154
787
RK120, ,
NOMESCO Finland
10.5
14.2
27
26
Z97.8
ICD-10 Finland
Presence of other specified devices
6.4
14.1
23
36
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
13.8
1182
9749
48609
ICD-8 Finland
Pneumonia, unspecified
3.6
13.7
44
123
DED00
NOMESCO Finland
Obliteration of cavity after partial excision of mastoid
+∞
13.5
13
*
DCA40
NOMESCO Finland
Fat patching or other similar technique without opening of tympanic membrane
+∞
13.5
13
*
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
+∞
13.5
13
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
13.5
627
4668
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
13.1
557
4077
J20
ICD-10 Finland
Acute bronchitis
1.7
12.9
255
1570
UDC10
NOMESCO Finland
Tympanoscopy
50.2
12.8
15
*
S02AA30
ATC
antiinfectives, combinations; otic
2.2
12.8
106
490
4129
FHL
Other measure in this category
70.2
12.6
14
*
R03DC03
ATC
montelukast; oral
1.5
12.6
397
2735
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
3.2
12.3
47
147
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
4.4
12.1
30
69
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
12.1
818
6472
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.7
12.1
231
1410
S01AA01
ATC
chloramphenicol; ophthalmic
2.1
12.1
119
589
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
46.8
11.9
14
*
R01AD05
ATC
budesonide; nasal
1.8
11.8
177
1010
H60.0
ICD-10 Finland
Abscess of external ear
5.1
11.7
24
47
D07AC01
ATC
betamethasone; topical
1.4
11.7
874
7019
4452
FHL
Tonsil surgery
2.4
11.7
78
329
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
11.7
113
556
R02
ICPC
Shortness of breath/dyspnoea
1.5
11.5
339
2298
J01FA15
ATC
telithromycin; oral
1.7
11.5
209
1260
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
4.3
11.5
29
68
Z2221
NOMESCO Finland
Medical doctor
1.4
11.4
655
5043
RK290, ,
NOMESCO Finland
11.8
11.3
20
17
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.9
11.3
138
738
R03AC03
ATC
terbutaline; inhalant
1.5
11.2
321
2163
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
3.1
11.2
46
151
H91.8
ICD-10 Finland
Other specified hearing loss
3.5
11.1
37
106
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
3.5
11.0
37
107
DCA30
NOMESCO Finland
Exploration of middle ear
43.5
10.9
13
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.9
10.9
132
704
J01FA01
ATC
erythromycin; systemic
1.5
10.7
318
2159
R51.80
ICD-10 Finland
Headache
1.5
10.7
397
2822
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
10.5
487
3606
R74
ICPC
Upper respiratory infection acute
1.3
10.5
862
6995
H69.0
ICD-10 Finland
Patulous Eustachian tube
9.2
10.5
21
23
DCB00
NOMESCO Finland
Excision of lesion of middle ear
110.4
10.4
11
*
3890A
ICD-9 Finland
Deafness, Conductive deafness
110.4
10.4
11
*
4148
FHL
Radical cutting and cavity filling
+∞
10.4
10
*
E000001, ,
ATC
1.4
10.4
490
3641
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
10.3
482
3576
L17
ICPC
Foot/toe symptom/complaint
1.3
10.0
760
6091
D06AX01
ATC
fusidic acid; topical
1.6
10.0
231
1482
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
40.2
10.0
12
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
9.9
1320
11407
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.8
9.9
134
740
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
9.9
749
5998
R03DA04
ATC
theophylline; systemic, rectal
1.9
9.9
131
719
J45
ICD-10 Finland
Asthma
1.6
9.9
246
1605
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
5.2
9.8
20
39
Q35.1
ICD-10 Finland
Cleft hard palate
26.1
9.8
13
5
DCA00
NOMESCO Finland
Biopsy of tympanic membrane or middle ear
55.2
9.6
11
*
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
3.3
9.4
35
108
H74.4
ICD-10 Finland
Polyp of middle ear
+∞
9.4
9
*
5251
FHL
Hypotension
+∞
9.4
9
*
DEB35
NOMESCO Finland
Radical mastoidectomy with tympanoplasty
+∞
9.4
9
*
H02
ICPC
Hearing complaint
1.5
9.4
332
2337
J02AC01
ATC
fluconazole; systemic
1.3
9.3
824
6735
E0000UV, ,
ATC
1.3
9.3
1050
8863
R01AD11
ATC
triamcinolone; nasal
1.7
9.3
189
1173
L04AA01
ATC
[U] ciclosporin
3.4
9.3
32
94
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
9.3
444
3302
T16
ICD-10 Finland
Foreign body in ear
3.3
9.3
34
104
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
9.3
668
5305
M01AE02
ATC
naproxen; oral, rectal
1.3
9.2
1405
12311
50300
ICD-8 Finland
Chronic sinusitis, Maxillaris cum empyemate
5.0
9.1
19
38
4711A
ICD-9 Finland
Nasal polyps, Polypoid sinus degeneration
5.0
9.1
19
38
R42
ICD-10 Finland
Dizziness and giddiness
1.4
9.1
537
4137
R06AX13
ATC
loratadine; oral
1.5
9.1
333
2360
H83.1
ICD-10 Finland
Labyrinthine fistula
36.8
9.0
11
*
J33.0
ICD-10 Finland
Polyp of nasal cavity
2.2
9.0
72
330
ZXE00
NOMESCO Finland
One hour or less
1.3
8.9
917
7642
R03AC13
ATC
formoterol; inhalant
1.9
8.9
113
613
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
3.1
8.8
36
118
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
8.8
691
5551
N02AX02
ATC
tramadol; systemic, rectal
1.3
8.7
980
8252
DEE00
NOMESCO Finland
Osseous fixation of hearing aid
50.1
8.7
10
*
H62.2*B44.8
ICD-10 Finland
Otitis externa in aspergillosis
50.1
8.7
10
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
8.6
332
2374
DPA30
NOMESCO Finland
Sphenotomy
4.4
8.6
21
48
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
8.6
97
506
H81.3
ICD-10 Finland
Other peripheral vertigo
2.3
8.4
64
287
H74.0
ICD-10 Finland
Tympanosclerosis
90.3
8.4
9
*
Z3226
NOMESCO Finland
Physiotherapist
1.4
8.4
422
3163
ZZG00
NOMESCO Finland
Graft of cartilage
12.8
8.4
14
11
XG410
NOMESCO Finland
Flow-volume spirometry
1.9
8.4
97
511
R03BB01
ATC
ipratropium bromide; inhalant
1.9
8.4
94
490
1451
FHL
Otomicroscopy and paper place
+∞
8.3
8
*
R01AD12
ATC
fluticasone furoate; nasal
1.3
8.3
734
5985
R4110
NOMESCO Finland
Physiotherapy
1.3
8.2
636
5091
Z2446
NOMESCO Finland
Social worker
1.6
8.2
172
1078
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
8.2
759
6227
X58
ICD-10 Finland
Exposure to other specified factors
1.4
8.2
364
2672
46401
ICD-8 Finland
Acute laryngitis and tracheitis, Laryngitis acuta (subglottica)
4.0
8.1
22
55
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
8.1
301
2140
N02BE01
ATC
paracetamol; systemic, rectal
1.3
8.1
2317
21760
R06AX27
ATC
desloratadine; oral
1.3
8.0
687
5574
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.0
983
8350
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.5
8.0
228
1536
J01FA06
ATC
roxithromycin; oral
1.3
8.0
878
7360
H91
ICD-10 Finland
Other hearing loss
3.2
7.9
31
99
M79.6
ICD-10 Finland
Pain in limb
1.3
7.9
1043
8927
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
7.9
471
3625
K02.1
ICD-10 Finland
Caries of dentine
1.2
7.9
1502
13407
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
1.8
7.9
104
572
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
7.8
1033
8843
XF400
NOMESCO Finland
ECG with 12 standard connections
1.4
7.8
370
2746
Q90.9
ICD-10 Finland
Down syndrome, unspecified
45.1
7.7
9
*
ZXC10
NOMESCO Finland
Use of laser
2.4
7.7
52
222
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
7.7
139
839
RK530, ,
NOMESCO Finland
18.4
7.6
11
6
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
18.4
7.6
11
6
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
3.2
7.5
28
87
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.7
7.5
123
722
Q89.34
ICD-10 Finland
Cartagena syndrome (immotile cilia)
80.3
7.4
8
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
7.4
510
4010
H69.8
ICD-10 Finland
Other specified disorders of Eustachian tube
6.5
7.4
18
28
Z98.8
ICD-10 Finland
Other specified postsurgical states
2.8
7.3
35
126
B01AB05
ATC
enoxaparin; parenteral
1.3
7.3
682
5588
4119
FHL
Other measure in this category
+∞
7.3
7
*
H70.9
ICD-10 Finland
Mastoiditis, unspecified
+∞
7.3
7
*
3811A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic serous otitis media
+∞
7.3
7
*
49099
ICD-8 Finland
Bronchitis, unspecified
3.2
7.2
27
84
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
7.2
332
2450
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
5.8
7.2
19
33
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
2.9
7.2
32
111
DFE00
NOMESCO Finland
Insertion of cochlear implant
7.9
7.1
15
19
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
2.7
7.1
36
134
R05FB02
ATC
cough suppressants and expectorants; systemic
1.3
7.0
781
6533
H68.0
ICD-10 Finland
Eustachian salpingitis
8.8
7.0
14
16
49302
ICD-8 Finland
Asthma, Rhinitis allergica cum asthmate bronchiali
3.9
7.0
20
52
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.5
6.9
245
1723
J01EB05
ATC
sulfafurazole; systemic
7.5
6.9
15
20
S06.0
ICD-10 Finland
Concussion
1.4
6.9
273
1963
W19
ICD-10 Finland
Unspecified fall
1.5
6.9
237
1660
DFX03
NOMESCO Finland
Review, maintenance and user education for hearing aid
3.6
6.9
22
62
R03AK08
ATC
formoterol and beclometasone; inhalant
1.8
6.9
99
561
7806A
ICD-9 Finland
General symptoms, Pyrexia of unknown origin
3.5
6.8
23
67
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
1.9
6.8
84
453
WX110
NOMESCO Finland
Infiltration anesthesia
1.2
6.8
1847
17002
R06AE09
ATC
levocetirizine; oral
1.4
6.8
325
2414
D07AB08
ATC
desonide; topical
1.4
6.8
248
1757
DHB20
NOMESCO Finland
Polypectomy of internal nose
2.6
6.8
38
149
38408
ICD-8 Finland
Other inflammatory diseases of ear, Alii definiti
40.1
6.8
8
*
H95.9
ICD-10 Finland
Postprocedural disorder of ear and mastoid process, unspecified
40.1
6.8
8
*
D01AC02
ATC
miconazole; topical
1.6
6.7
164
1067
WX002
NOMESCO Finland
Sedation and analgesia
1.3
6.7
412
3183
DHA10
NOMESCO Finland
Biopsy of cavity of nose
3.5
6.7
22
63
Z02.7
ICD-10 Finland
Issue of medical certificate
1.5
6.7
177
1173
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
7.2
6.7
15
21
J01.1
ICD-10 Finland
Acute frontal sinusitis
2.5
6.7
41
168
S02CA01
ATC
prednisolone and antiinfectives; otic
22.6
6.7
9
*
201
Kela drug reimbursment
Chronic cardiac insufficiency
1.6
6.7
131
809
N07CA01
ATC
betahistine; oral
1.6
6.6
151
967
D07AC13
ATC
mometasone; topical
1.3
6.6
636
5226
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.3
6.6
746
6251
SPAT1044
SPAT
Tympanometry
2.2
6.5
52
239
J45.8
ICD-10 Finland
Mixed asthma
2.0
6.5
67
340
A46
ICD-10 Finland
Erysipelas
1.4
6.5
320
2389
J46
ICD-10 Finland
Status asthmaticus
2.0
6.5
63
313
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
6.5
792
6690
R01BA01
ATC
phenylpropanolamine; oral
1.8
6.5
100
579
H27
ICPC
Fear of ear disease
2.5
6.4
37
147
A01AB09
ATC
miconazole; local oral
1.5
6.4
184
1241
DDD10
NOMESCO Finland
Interposition between malleus and stapes
70.0
6.4
7
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
6.4
874
7472
J35.0
ICD-10 Finland
Chronic tonsillitis
1.7
6.3
118
719
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.4
6.3
250
1797
H60.2
ICD-10 Finland
Malignant otitis externa
18.0
6.3
9
5
R01AD58
ATC
fluticasone, combinations; nasal
1.3
6.3
556
4519
3829X
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified otitis media
+∞
6.2
6
*
38410, ,
ICD-8 Finland
+∞
6.2
6
*
3851A
ICD-9 Finland
Other disorders of middle ear and mastoid, Adhesive middle ear disease
+∞
6.2
6
*
3858X
ICD-9 Finland
Other disorders of middle ear and mastoid
+∞
6.2
6
*
38200
ICD-8 Finland
Acute / Acute otitis media with mastoiditis
+∞
6.2
6
*
DCB10
NOMESCO Finland
Freeing of adhesions of middle ear
+∞
6.2
6
*
0419X
ICD-9 Finland
Bacterial infection in conditions classified elsewhere and of unspecified site, Bacterial infection, unspecified
+∞
6.2
6
*
M01AB05
ATC
diclofenac; systemic, rectal
1.2
6.2
1506
13641
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
6.2
360
2759
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.6
6.2
123
763
N05BB01
ATC
hydroxyzine; systemic
1.6
6.2
139
889
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
1.7
6.2
105
625
H05
ICPC
Bleeding ear
4.0
6.2
17
43
RK220, ,
NOMESCO Finland
4.0
6.2
17
43
A02BC02
ATC
pantoprazole; systemic
1.2
6.2
1614
14729
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.3
6.1
404
3152
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
2.1
6.1
53
252
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.4
6.1
269
1970
F83
ICD-10 Finland
Mixed specific developmental disorders
3.0
6.1
26
88
J01MA14
ATC
moxifloxacin; systemic
1.5
6.1
186
1272
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.4
6.1
287
2127
Q38.1
ICD-10 Finland
Ankyloglossia
4.1
6.1
16
39
C03CA01
ATC
furosemide; systemic
1.3
6.0
688
5758
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.0
6.0
58
288

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
677
2904
2.74
103.15
2.8
1.7
—
—
—
0
0
520
2857
2.00
40.48
1.8
1.4
—
—
—
0
0
554
3484
1.73
26.99
2.3
2.0
—
—
—
0
0
1388
11714
1.35
14.07
7.7
6.6
0.66
0.67
%
0.38
1292
11008
1388
11741
1.35
13.73
7.7
6.7
8.88
8.84
%
0.21
1293
11040
1386
11723
1.35
13.72
7.6
6.6
2.91
2.82
%
0.73
1292
11008
1392
11824
1.34
13.19
7.3
6.5
56.44
56.99
%
0.92
1317
11317
386
2669
1.51
11.99
4.5
4.7
31.87
32.40
%
0.43
266
1794
1404
12067
1.32
11.71
7.5
6.6
28.40
28.07
%
0.50
1335
11476
1504
13094
1.31
11.22
7.5
6.7
0.20
0.19
e9/l
1.25
1287
11397
59
233
2.56
10.19
1.8
1.3
0.33
0.40
g/l
1.23
47
169
59
233
2.56
10.19
1.8
1.3
6.30
6.87
g/l
0.89
47
168
59
233
2.56
10.19
1.8
1.3
2.89
2.91
g/l
0.03
47
169
250
1646
1.57
9.66
1.5
1.3
429.74
290.12
u/ml
0.47
239
1522
1447
12688
1.28
9.57
7.3
6.4
0.04
0.04
e9/l
1.27
1230
10878
1443
12664
1.28
9.42
7.3
6.4
0.61
0.59
e9/l
3.16
1228
10855
57
231
2.50
9.36
1.8
1.3
—
—
—
0
0
313
2179
1.49
9.34
3.9
4.2
7.35
7.35
ph
0.08
219
1576
1473
12978
1.27
9.24
7.3
6.5
2.05
1.95
e9/l
0.65
1282
11396
30
87
3.47
8.91
2.1
2.5
0.45
0.30
e9/l
0.43
15
36
165
1016
1.66
8.41
2.4
1.4
5.97
17.57
iu/ml
—
9
28
587
4639
1.33
8.32
4.5
4.0
267.58
443.41
ng/l
0.90
452
3549
54
230
2.37
8.02
2.5
2.4
1412.00
1254.93
e6/l
0.52
46
194
1915
17559
1.27
8.01
4.8
4.3
12.48
11.66
mm/h
1.58
1773
16424
1214
10571
1.25
7.98
2.2
2.1
93.72
95.87
pmol/l
0.80
647
5731
748
6150
1.29
7.89
4.4
4.3
88.64
88.03
%
0.27
733
6028
79
404
1.98
7.45
2.0
1.7
0.68
0.78
g/l
0.49
62
324
818
6862
1.27
7.24
4.6
4.4
—
—
—
0
0
141
873
1.65
7.08
1.5
1.2
—
—
—
0
0
1397
12463
1.23
7.05
6.6
6.4
11.35
12.17
umol/l
1.42
1318
11880
42
173
2.45
6.76
2.5
2.5
610.33
564.90
e6/l
0.19
33
135
1944
18002
1.24
6.74
8.7
8.0
79.91
80.31
u/l
0.13
1829
17111
1566
14185
1.23
6.67
5.9
5.2
6.72
6.66
mmol/l
0.44
1464
13390
1226
10843
1.23
6.56
7.7
6.8
1.21
1.21
mmol/l
0.13
1117
10033
156
1013
1.57
6.47
5.2
5.1
24.56
24.63
mmol/l
0.11
145
951
810
6871
1.25
6.37
3.8
3.3
1560.28
1490.10
ng/l
0.20
681
5930
646
5349
1.27
6.24
1.6
1.5
2.48
2.36
g/l
0.69
377
3337
41
175
2.36
6.14
2.6
2.6
225.44
219.54
e6/l
0.08
34
143
1222
10864
1.22
6.05
16.5
15.4
1.26
1.27
inr
0.07
1002
9112
707
5969
1.24
5.71
3.0
2.8
356.88
345.61
umol/l
1.85
615
5284
876
7569
1.22
5.68
2.8
2.6
57.77
70.35
u/l
0.59
819
7042
242
1764
1.41
5.67
4.9
4.4
5.18
5.14
kpa
0.34
232
1691
1206
10758
1.21
5.64
5.3
5.2
35.80
35.77
g/l
0.07
1130
10091
1345
12122
1.20
5.64
8.3
7.3
1.21
1.21
mmol/l
0.04
1180
10487
254
1869
1.39
5.63
4.2
4.2
97.22
87.42
ng/l
0.46
224
1626
491
3990
1.28
5.48
2.8
2.6
2.33
2.33
g/l
0.11
452
3691
261
1941
1.38
5.43
3.0
2.8
10.24
10.64
g/l
0.69
246
1780
519
4274
1.26
5.18
2.8
2.6
12.58
13.09
umol/l
0.85
486
3988
454
3679
1.28
5.17
2.9
2.6
21.33
22.70
%
1.51
419
3432
44
209
2.12
5.17
2.6
2.3
39.72
37.78
%
0.34
44
209
211
1528
1.41
5.15
1.7
2.0
1.32
1.38
g/l
0.16
194
1411
177
1245
1.45
5.07
5.2
4.8
—
—
—
0
0
416
3355
1.28
4.92
1.4
1.4
500.71
495.77
titre
0.02
85
700
232
1725
1.37
4.85
5.0
4.4
7.41
7.41
ph
0.23
190
1438
902
7922
1.20
4.79
2.5
2.5
—
—
—
0
0
2462
23671
1.26
4.78
18.9
15.7
24.34
24.51
mg/l
0.09
2081
19362
1534
14119
1.18
4.74
10.3
9.5
4.13
4.13
e9/l
0.03
1303
12232
142
2031
0.68
4.69
5.0
3.9
—
—
—
0
0
833
7280
1.20
4.64
2.2
2.2
224.64
232.78
u/l
0.09
779
6912
786
6843
1.20
4.55
2.5
2.4
2.67
2.77
mg/l
0.59
668
5904
701
6045
1.21
4.48
2.5
2.4
—
—
—
0
0
101
650
1.57
4.45
3.5
3.4
4.18
1.87
index
0.87
55
341
1740
16234
1.18
4.43
3.4
3.3
48.23
46.24
u/l
0.38
1636
15332
520
4356
1.24
4.42
3.1
3.0
1.14
1.30
e6/l
0.29
266
2344
788
8952
0.84
4.41
2.9
3.0
—
—
—
0
0
484
4033
1.24
4.31
3.2
3.2
3.09
2.39
e6/l
0.73
228
2013
275
2146
1.31
4.19
1.2
1.2
—
—
—
0
0
798
7002
1.19
4.19
3.1
3.0
0.00
0.02
0.74
11
148
39
193
2.03
4.18
3.5
3.0
25.56
24.00
mu/l
0.11
39
178
93
597
1.58
4.17
1.8
1.6
19214.73
12759.96
e6/l
0.30
60
421
414
3407
1.25
4.12
7.2
6.1
1.08
1.06
mmol/l
0.47
387
3162
108
722
1.51
4.05
6.1
7.0
1.59
1.33
mmol/l
0.86
98
625
451
3770
1.23
3.89
2.3
2.4
29.57
29.79
s
0.30
439
3658
50
278
1.81
3.84
1.9
2.2
24.25
23.23
mg/l
0.05
16
100
920
8226
1.17
3.81
3.8
3.6
7.49
7.78
mmol/l
1.08
775
7059
33
161
2.06
3.70
1.2
2.3
8.30
6.81
mmol/l
0.67
25
113
788
6980
1.18
3.63
1.8
1.7
19.68
19.88
nmol/l
0.14
681
5952
17
62
2.75
3.58
1.3
1.2
—
—
—
0
0
197
1517
1.32
3.35
3.7
3.5
4.47
4.54
pmol/l
0.51
167
1365
1690
15905
1.15
3.34
5.1
4.7
1448.52
1602.58
e6/l
0.05
23
223
27
128
2.12
3.29
1.7
1.5
1.40
1.24
nmol/l
0.31
19
94
345
2856
1.24
3.27
2.9
2.8
7.43
8.08
umol/l
0.32
297
2501
137
1003
1.38
3.24
1.6
1.8
8.56
7.50
iu/ml
0.16
27
246
192
1483
1.32
3.20
9.9
9.8
24.35
24.26
mmol/l
0.14
185
1451
602
5268
1.18
3.17
2.5
1.8
1.16
1.34
mg/l
0.80
466
4009
662
5843
1.17
3.14
3.9
3.8
0.40
0.10
—
5
58
823
7388
1.16
3.13
4.3
4.3
9.48
8.84
mg/mmol
0.15
530
4740
291
2377
1.25
3.12
2.2
2.4
0.21
0.21
g/l
0.14
272
2214
39
216
1.82
3.09
1.5
1.2
193675.64
114346.67
e6/l
0.25
22
144
97
675
1.45
3.06
1.2
1.3
5.67
3.61
u/ml
0.23
11
64
2215
21310
1.17
3.06
6.5
6.0
39.19
38.91
mmol/mol
0.76
2068
19989
339
2825
1.23
3.03
8.5
8.1
5.16
5.09
kpa
0.58
325
2707
339
2826
1.23
3.02
8.5
8.0
11.64
12.37
kpa
1.67
325
2712
1191
10995
1.14
3.01
2.6
2.5
76.47
75.97
nmol/l
0.23
1061
9990
381
3219
1.21
2.97
1.3
1.2
—
—
—
0
0
898
8142
1.15
2.95
3.6
3.2
31.05
34.78
u/l
0.95
847
7704
180
1396
1.31
2.94
10.2
10.8
15.68
15.95
%
0.69
174
1339
22
101
2.19
2.92
1.0
1.0
9.55
16.44
u/ml
0.72
12
69
96
675
1.44
2.89
1.3
1.3
5.96
15.94
u/ml
1.12
12
110
803
7235
1.15
2.88
3.7
3.6
48.60
52.58
mg/l
0.19
534
4781
1008
9229
1.14
2.85
4.4
4.0
70.61
94.49
e6/l
0.68
706
6491
335
2809
1.22
2.82
8.5
8.0
0.85
0.95
mmol/l
0.15
272
2282
690
6158
1.16
2.81
1.4
1.4
2.44
1.76
u/ml
0.51
147
1642
52
323
1.62
2.78
3.3
2.5
—
—
—
0
0
357
3023
1.21
2.73
3.3
3.1
4.93
4.76
e9/l
0.11
290
2621
19
85
2.24
2.70
1.9
2.0
28.26
30.89
%
0.33
19
85
20
92
2.18
2.66
1.1
1.0
13.75
10.57
u/ml
—
5
16
30
161
1.87
2.66
2.7
2.6
0.84
0.69
e9/l
0.70
30
156
334
2824
1.21
2.60
8.7
8.1
7.41
7.42
ph
1.02
178
1550
146
1881
0.76
2.60
4.9
3.7
1.22
1.23
mmol/l
0.69
124
1601
39
229
1.71
2.59
3.6
3.5
14.25
13.58
index
0.10
28
136
278
2309
1.23
2.59
9.6
7.6
10.27
9.62
mmol/l
0.80
269
2220
489
4278
1.17
2.57
1.4
1.3
21.96
30.42
iu/ml
2.05
135
1245
72
491
1.48
2.57
7.4
8.5
12.12
11.30
mmol/l
0.95
65
436
456
3968
1.18
2.56
1.3
1.3
12.27
10.07
u/ml
0.26
138
1515
28
149
1.89
2.55
1.8
1.4
18.13
24.34
umol/l
0.59
28
136
72
492
1.47
2.55
7.4
8.5
105.77
105.27
mmol/l
0.46
65
437
471
4122
1.17
2.47
4.3
3.5
0.81
0.82
mmol/l
0.98
439
3894
28
151
1.86
2.46
2.0
3.2
—
—
—
0
0
229
1879
1.24
2.41
4.3
3.2
189.90
215.08
ng/l
0.52
205
1712
172
1366
1.28
2.40
1.2
1.1
—
1.82
—
0
12
1209
11292
1.12
2.37
2.9
2.8
—
—
estimate
—
0
0
31
176
1.77
2.33
1.1
1.1
0.26
1.90
u/ml
0.62
12
56
814
7434
1.13
2.32
3.4
3.2
—
—
—
0
0
40
247
1.63
2.24
1.6
1.5
63.08
60.77
%
0.15
26
160
40
247
1.63
2.24
3.2
3.9
—
—
—
0
0
282
2386
1.20
2.20
2.4
2.5
34.08
38.35
u/l
0.43
240
2012
275
2326
1.20
2.16
9.8
8.9
120.43
121.42
g/l
0.34
268
2267
1919
18453
1.12
2.12
4.4
4.3
14.71
14.76
pmol/l
0.33
1734
16881
797
7314
1.12
2.07
6.8
6.4
—
—
—
0
0
107
815
1.32
2.07
2.0
1.9
—
—
—
0
0
872
8045
1.12
2.07
3.7
3.5
142.54
81.36
e6/l
0.28
673
6173
2252
21871
1.13
2.06
5.0
4.8
5.93
5.88
mmol/l
0.80
2070
20092
2241
21761
1.13
2.04
5.4
5.2
1.88
1.91
mu/l
0.41
2074
20222
6
15
4.00
2.04
8.0
5.8
—
—
—
0
0
32
192
1.67
2.02
1.1
1.1
—
—
—
0
0
293
2509
1.19
2.02
9.2
8.4
95.37
95.57
%
0.22
278
2417
277
2370
1.19
1.94
10.6
8.8
—
—
—
0
0
64
455
1.42
1.92
1.1
1.1
5.45
7.35
u/ml
0.39
32
218
68
490
1.40
1.89
1.1
1.1
6.62
4.08
u/ml
0.46
37
260
30
181
1.66
1.88
1.1
1.1
—
—
—
0
0
45
301
1.50
1.85
2.8
2.6
—
—
—
0
0
952
8874
1.11
1.84
4.2
3.8
120.68
67.17
ng/l
0.35
614
6119
73
536
1.37
1.83
1.2
1.2
81.80
47.94
u/ml
—
8
48
30
183
1.65
1.81
1.3
1.2
8.82
3.86
u/ml
—
9
60
40
263
1.53
1.78
2.6
2.3
2.40
1.40
g/24h
0.28
18
162
31
192
1.62
1.77
3.4
2.7
35.52
30.51
mg/l
0.29
23
139
913
9749
0.91
1.69
4.0
3.8
0.01
0.07
estimate
0.69
158
2286
2410
23582
1.13
1.67
21.6
18.5
139.63
139.59
mmol/l
0.35
2357
23081
143
1167
1.24
1.66
1.8
1.8
1.54
1.48
g/l
0.35
125
1023
114
907
1.27
1.65
1.3
1.2
0.18
0.97
u/ml
—
6
62
2181
21228
1.11
1.65
4.2
4.0
1.31
1.27
mmol/l
1.78
2010
19610
42
285
1.48
1.64
1.2
1.3
—
57.44
—
0
12
50
352
1.43
1.62
1.3
1.4
21.41
20.71
u/l
0.06
39
298
75
566
1.33
1.61
1.5
1.5
—
—
—
0
0
279
2434
1.16
1.58
1.5
1.5
—
—
—
0
0
33
215
1.54
1.56
1.7
1.5
1.31
1.21
promille
0.14
26
169
1103
10425
1.09
1.55
3.6
3.5
6.13
6.26
ph
3.58
581
5883
79
606
1.31
1.53
1.3
1.4
—
—
—
0
0
93
730
1.28
1.52
1.4
1.4
286.10
284.99
ug/g
0.02
53
410
48
341
1.41
1.50
6.9
6.6
10.66
12.03
mg/l
0.89
42
315
2410
23624
1.12
1.46
21.9
18.6
3.97
3.97
mmol/l
0.33
2350
23077
28
179
1.57
1.45
1.1
1.1
—
—
—
0
0
45
319
1.42
1.44
1.1
1.2
—
—
—
0
0
113
916
1.24
1.43
1.3
1.3
231.38
225.51
miu/ml
0.06
39
424
13
66
1.97
1.43
1.7
1.8
—
—
—
0
0
113
917
1.24
1.42
1.6
1.6
10.56
14.98
u/ml
0.68
23
221
877
8235
1.09
1.41
3.5
3.4
2.35
2.35
mmol/l
0.09
799
7484
75
580
1.30
1.39
1.1
1.1
1.03
2.20
u/ml
1.44
36
322
11
53
2.08
1.38
1.0
1.1
—
—
—
0
0
33
222
1.49
1.38
3.0
2.7
—
—
—
0
0
129
1067
1.22
1.37
1.3
1.3
—
—
—
0
0
27
174
1.56
1.37
3.0
3.4
21.33
33.57
mg/l
0.44
18
134
448
4075
1.12
1.36
1.8
1.8
1123.63
1148.80
nmol/l
0.23
326
3081
10
47
2.13
1.33
1.7
1.7
—
—
—
0
0
36
250
1.45
1.30
1.1
1.1
—
—
—
0
0
6
24
2.50
1.30
1.8
1.4
118.00
158.95
mmol/l
—
6
19
85
677
1.26
1.28
1.1
1.1
1.77
2.63
u/ml
0.40
46
382
295
2628
1.14
1.28
1.4
1.4
—
—
—
0
0
663
7102
0.91
1.28
4.3
4.0
0.00
0.00
estimate
1.34
181
2547
82
652
1.26
1.26
1.7
2.1
3.80
12.06
iu/l
0.51
31
288
362
3273
1.12
1.24
1.6
1.6
—
—
—
0
0
54
407
1.33
1.23
1.1
1.1
47.09
1344.59
iu/ml
0.53
11
101
306
2740
1.13
1.23
5.7
4.2
7.37
7.38
ph
1.30
163
1615
665
7110
0.92
1.23
3.4
3.3
0.01
0.17
estimate
0.78
152
2191
222
1947
1.15
1.22
1.4
1.4
—
—
—
0
0
67
522
1.29
1.21
1.4
1.5
152.72
146.18
au/ml
0.17
25
151
13
226
0.57
1.20
1.0
1.2
—
—
—
0
0
222
1950
1.15
1.20
2.5
2.5
0.41
0.45
e6/l
0.20
214
1860
42
306
1.38
1.19
1.4
1.3
—
—
—
0
0
255
2263
1.14
1.18
2.8
2.7
73.02
68.91
e9/l
0.83
176
1644
6
26
2.31
1.18
1.0
1.2
0.03
0.03
u/ml
—
6
26
51
385
1.33
1.16
1.1
1.2
—
—
—
0
0
2324
22807
1.09
1.16
5.6
5.4
2.65
2.68
mmol/l
1.02
2163
21280
170
1471
1.16
1.13
7.3
7.0
24.16
24.44
mmol/l
0.41
163
1400
2276
22327
1.09
1.12
4.9
4.7
1.39
1.43
mmol/l
5.65
2111
20798
762
7182
1.08
1.11
4.5
4.1
7.40
7.40
ph
0.10
531
5150
595
5553
1.09
1.09
2.9
2.8
5.27
5.94
e6/l
0.52
550
5064
2522
24864
1.11
1.09
23.1
20.0
78.70
77.72
umol/l
0.65
2484
24559
7
32
2.19
1.08
1.0
1.0
—
—
—
0
0
133
1134
1.18
1.07
2.3
2.1
0.03
0.72
estimate
0.48
34
353
1960
20043
0.93
1.05
23.4
19.2
13.69
13.56
%
3.95
1930
19766
216
1914
1.14
1.05
3.0
2.6
6.05
6.10
ph
0.37
137
1285
169
1474
1.16
1.03
1.3
1.3
36.03
52.98
au/ml
—
10
103
75
607
1.24
1.03
1.2
1.3
214.95
232.91
u/ml
0.29
43
349
5
22
2.27
1.03
2.6
2.5
1.12
1.16
mg/l
—
5
17
17
106
1.61
1.02
2.8
2.8
—
—
—
0
0
2289
22485
1.08
1.02
5.0
4.8
4.49
4.56
mmol/l
3.22
2133
21073
1260
12126
1.07
1.02
3.6
3.1
115.21
114.97
ug/l
0.01
1164
11354
56
439
1.28
1.01
1.1
1.1
0.08
0.33
u/ml
1.80
20
160
15
91
1.65
1.00
1.3
1.2
0.49
4.57
u/ml
—
10
63
7
35
2.00
1.00
1.0
1.1
—
—
—
0
0
9
49
1.84
0.98
1.6
1.9
—
—
—
0
0
219
1953
1.13
0.98
2.2
2.4
6.64
7.07
ug/l
0.13
189
1737
90
1077
0.83
0.98
1.6
1.7
249.93
299.15
mu/l
2.43
83
984
113
961
1.18
0.96
2.8
2.5
20.53
21.19
s
1.11
104
864
98
823
1.20
0.96
2.5
3.5
1215.21
4811.71
u/ml
0.53
87
712
153
1335
1.15
0.95
4.1
3.2
1.43
1.21
%
1.64
153
1324
8
146
0.55
0.92
2.4
1.8
7.85
8.19
mmol/l
—
8
146
6
28
2.14
0.91
2.0
7.3
0.23
0.19
%
—
6
28
18
118
1.53
0.90
4.1
2.2
1.61
1.90
umol/l
0.48
18
110
291
2655
1.11
0.89
5.7
4.2
1.73
1.75
mmol/l
0.04
254
2266
20
135
1.48
0.89
4.0
3.2
1260.10
1103.96
u/ml
0.12
20
135
506
4737
1.08
0.88
2.8
2.9
2.45
2.45
mmol/l
0.05
453
4251
42
537
0.78
0.86
4.0
4.5
—
—
—
0
0
326
3000
1.10
0.85
2.9
2.8
1.80
1.75
%
0.28
278
2674
6
31
1.94
0.84
3.7
4.5
—
—
—
0
0
67
551
1.22
0.84
2.5
2.8
31.30
34.69
umol/l
0.66
60
498
19
129
1.48
0.83
1.3
2.0
3.03
4.88
nmol/l
0.44
14
104
99
1153
0.85
0.82
1.8
1.6
—
—
—
0
0
180
1608
1.13
0.82
2.5
2.4
23.74
21.21
au/ml
0.15
24
177
20
138
1.45
0.81
1.7
2.5
4.88
1.76
u/ml
—
7
52
2616
25899
1.10
0.81
27.5
23.6
252.21
250.65
e9/l
0.62
2565
25348
2618
25920
1.10
0.81
27.6
23.8
135.07
135.29
g/l
0.32
2591
25642
8
47
1.70
0.80
3.3
7.9
5.80
5.06
kpa
—
8
47
8
47
1.70
0.80
1.0
1.3
1.88
7.17
u/ml
—
8
38
2618
25921
1.10
0.80
27.5
23.6
7.04
6.82
e9/l
2.59
2553
25295
2617
25911
1.10
0.80
27.3
23.5
30.17
30.21
pg
0.61
2590
25627
2617
25912
1.10
0.80
27.4
23.6
4.51
4.51
e12/l
0.16
2553
25298
2617
25912
1.10
0.80
28.0
24.1
40.30
41.19
%
1.60
2591
25618
0
24
0.00
0.79
0.0
1.2
—
2.43
—
0
15
28
207
1.36
0.79
1.3
1.3
1.54
4.68
u/ml
1.48
19
122
26
190
1.37
0.78
1.0
1.2
0.90
2.52
u/ml
—
8
84
2496
24667
1.08
0.78
13.2
11.5
26.55
26.24
u/l
0.31
2415
23981
8
48
1.67
0.78
1.5
1.4
—
—
—
0
0
531
5619
0.93
0.77
5.5
4.6
—
—
—
0
0
17
115
1.48
0.76
1.1
1.2
—
—
—
0
0
49
395
1.24
0.75
4.3
5.6
396.73
362.27
umol/l
1.03
43
354
33
426
0.77
0.75
1.6
1.5
0.23
0.39
nmol/l
3.11
25
347
9
53
1.70
0.75
5.8
4.8
57.61
24.52
mg/mmol
—
9
45
113
986
1.15
0.74
6.5
5.9
0.90
0.87
%
0.24
108
921
87
744
1.17
0.74
1.3
1.1
—
—
—
0
0
174
1563
1.12
0.74
4.4
3.5
130.08
129.64
g/l
0.10
169
1517
730
6970
1.06
0.74
3.7
3.4
0.32
0.43
e6/l
1.04
536
5158
267
2455
1.10
0.73
2.4
2.2
373.17
378.20
nmol/l
0.15
246
2270
296
2735
1.09
0.73
5.7
4.2
5.82
5.83
kpa
0.04
289
2663
2615
25907
1.09
0.73
27.4
23.5
90.61
90.60
fl
0.05
2589
25626
5
25
2.00
0.72
1.4
2.0
62.40
44.36
umol/l
—
5
25
45
556
0.81
0.72
1.6
1.5
1.34
1.27
mm
0.37
34
393
7
39
1.80
0.72
1.7
1.4
—
—
—
0
0
52
425
1.23
0.72
1.2
1.3
77.14
39.76
u/l
0.39
45
367
7
40
1.75
0.71
4.0
1.6
93.29
28.31
pmol/l
—
7
35
147
1312
1.13
0.70
4.2
3.2
0.61
0.61
%
0.03
147
1304
59
490
1.21
0.70
2.6
3.5
0.80
0.83
nmol/l
0.19
44
398
7
41
1.71
0.70
1.0
1.2
—
—
—
0
0
7
41
1.71
0.70
1.0
1.2
—
—
—
0
0
13
85
1.53
0.68
1.8
1.4
114.29
107.53
nmol/l
—
7
62
612
5830
1.06
0.67
4.1
4.0
1.02
1.28
kg/l
0.50
415
3851
79
917
0.86
0.67
1.4
1.6
9.80
8.21
u/l
0.42
64
713
38
473
0.80
0.66
4.3
3.3
7.31
7.61
mmol/l
0.25
38
455
43
348
1.24
0.66
1.2
1.2
2.78
4.74
u/ml
0.66
18
162
698
7283
0.94
0.66
1.5
1.5
—
—
—
0
0
367
3442
1.08
0.64
2.5
2.7
171.23
128.84
ug/g
1.02
292
2762
17
120
1.42
0.64
1.2
2.9
172.63
126.90
umol/l
—
8
69
102
896
1.14
0.64
1.1
1.1
—
—
—
0
0
47
566
0.83
0.62
1.5
1.5
—
—
—
0
0
5
30
1.67
0.61
3.0
1.9
1.22
1.27
umol/l
—
5
21
233
2153
1.09
0.60
1.5
1.5
—
—
—
0
0
8
51
1.57
0.60
5.9
3.5
4.50
4.96
ug/l
—
8
51
111
987
1.13
0.59
2.1
1.9
1.26
1.74
ug/l
0.32
94
870
36
443
0.81
0.59
1.1
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
403
4256
0.94
0.58
3.1
3.2
0.95
0.77
ug/l
0.95
270
2722
298
3172
0.93
0.54
1.7
1.9
—
—
—
0
0
120
1080
1.12
0.54
6.3
5.6
1.81
1.60
%
1.35
114
1014
242
2253
1.08
0.54
2.6
2.1
0.02
0.01
estimate
0.20
47
480
82
930
0.88
0.54
1.1
1.1
1.49
1.51
g/l
0.28
82
930
14
99
1.42
0.54
3.7
3.1
—
—
—
0
0
42
349
1.21
0.53
1.6
1.5
—
—
—
0
0
42
349
1.21
0.53
1.6
1.5
—
—
—
0
0
42
349
1.21
0.53
1.6
1.5
—
—
—
0
0
42
349
1.21
0.53
1.6
1.5
—
—
—
0
0
93
826
1.13
0.52
8.1
5.4
1.50
1.44
mg/l
0.27
88
757
68
592
1.15
0.51
1.1
1.1
0.36
1.52
u/ml
2.25
32
285
9
134
0.67
0.51
2.4
2.0
16.07
16.45
%
—
9
134
52
443
1.18
0.51
3.2
3.3
4.12
4.15
e9/l
0.05
52
443
112
1008
1.12
0.51
1.3
1.2
—
—
—
0
0
11
157
0.70
0.51
1.3
1.2
—
—
—
0
0
77
872
0.88
0.50
1.1
1.1
0.62
0.66
ratio
0.24
13
94
11
75
1.47
0.50
1.2
1.3
—
—
—
0
0
13
92
1.41
0.50
1.2
1.1
—
—
—
0
0
6
41
1.46
0.50
1.0
2.8
16.68
20.56
mmol/l
—
6
36
328
3100
1.07
0.49
1.3
1.3
—
—
—
0
0
10
67
1.49
0.49
1.0
1.2
29.00
28.69
s
—
10
67
17
127
1.34
0.49
1.2
1.3
136.65
136.62
nmol/l
0.00
17
127
126
1383
0.91
0.49
1.5
1.6
921.78
1019.35
mu/l
0.51
101
1174
46
390
1.18
0.49
1.1
1.2
—
—
—
0
0
70
614
1.14
0.49
1.1
1.1
5.09
6.10
u/ml
0.24
39
357
44
518
0.85
0.48
1.5
1.3
—
—
—
0
0
11
76
1.45
0.48
1.9
2.6
2.45
2.77
mmol/l
0.22
11
68
249
2651
0.93
0.47
1.8
1.8
3.59
3.57
ratio
0.07
180
2001
208
2229
0.93
0.47
1.3
1.3
—
—
—
0
0
35
290
1.21
0.47
1.6
2.1
—
—
—
0
0
10
68
1.47
0.47
1.3
1.5
4.50
3.43
mmol/l
—
10
62
10
68
1.47
0.47
2.3
2.8
0.64
0.61
mmol/l
—
10
68
42
355
1.19
0.46
1.1
1.1
3.87
2.41
eliau/ml
0.57
12
162
15
111
1.35
0.46
3.6
3.0
—
—
—
0
0
5
82
0.61
0.45
1.4
1.8
—
—
—
0
0
1327
12999
1.04
0.45
4.2
3.9
0.02
0.12
estimate
0.43
190
2634
134
1229
1.09
0.45
2.7
2.4
2783.56
6176.82
u/l
1.56
52
459
72
639
1.13
0.44
4.6
3.4
—
—
—
0
0
50
576
0.87
0.44
1.6
1.5
—
—
—
0
0
34
284
1.20
0.43
1.4
1.3
—
—
—
0
0
66
583
1.13
0.43
3.5
3.1
58.23
58.35
%
0.03
66
583
14
185
0.76
0.43
1.2
2.1
1.17
1.45
u/field
—
6
102
11
78
1.41
0.43
1.2
1.1
—
—
—
0
0
5
32
1.56
0.42
1.2
1.3
—
—
—
0
0
21
167
1.26
0.41
1.1
1.3
0.52
0.59
ratio
0.45
13
92
37
434
0.85
0.41
1.1
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
1.44
—
0
9
471
4527
1.05
0.41
1.7
1.7
—
—
—
0
0
14
105
1.33
0.41
1.0
1.0
—
—
—
0
0
57
501
1.14
0.41
1.6
2.2
0.94
0.81
nmol/l
0.62
50
426
0
17
0.00
0.40
0.0
10.6
—
166.58
—
0
12
77
691
1.12
0.40
1.2
1.3
—
—
—
0
0
22
177
1.24
0.40
1.5
1.4
12.18
13.71
u/l
0.60
22
167
22
270
0.81
0.39
3.0
2.5
106.36
105.19
mmol/l
0.67
22
265
22
270
0.81
0.39
3.0
2.5
3.95
4.06
mmol/l
1.04
22
265
188
2003
0.93
0.39
1.6
1.6
3.46
3.46
mmol/l
0.02
123
1355
1574
15969
0.97
0.38
4.2
4.0
—
3367.57
—
0
30
11
80
1.38
0.38
3.9
4.3
—
—
—
0
0
39
335
1.17
0.38
1.4
1.6
325.28
331.57
mu/l
0.06
32
269
23
189
1.22
0.36
1.1
1.2
—
—
—
0
0
23
189
1.22
0.36
1.1
1.1
—
—
—
0
0
2049
20280
1.03
0.35
23.8
19.9
332.51
332.83
g/l
0.83
2040
20148
58
517
1.12
0.35
1.1
1.1
—
—
—
0
0
73
660
1.11
0.35
1.2
1.1
17.45
5.52
eliau/ml
—
6
83
15
117
1.28
0.35
1.1
1.1
362.73
200.63
iu/ml
0.55
15
117
98
900
1.09
0.35
3.0
2.6
—
—
—
0
0
58
518
1.12
0.34
1.1
1.1
—
—
—
0
0
1316
12942
1.03
0.34
4.1
3.9
6.53
4.62
estimate
0.11
203
2792
54
481
1.12
0.34
1.2
1.1
26.10
15.39
au/ml
0.33
11
116
243
2311
1.06
0.34
5.2
3.7
5.04
4.63
kpa
1.93
236
2252
19
154
1.23
0.33
1.7
1.5
105.32
81.75
umol/l
1.09
19
154
71
643
1.11
0.33
2.4
2.3
11.85
11.59
mg/l
0.06
64
600
56
502
1.12
0.32
2.8
2.4
52.60
82.87
ug/min
0.75
29
310
97
895
1.09
0.32
2.2
2.2
1237.46
485.57
ug/l
0.44
91
846
18
146
1.23
0.32
1.0
1.0
—
—
—
0
0
67
608
1.10
0.31
2.4
2.2
127.91
130.20
g/l
0.31
47
490
18
219
0.82
0.31
1.4
1.2
—
—
—
0
0
22
262
0.84
0.31
3.0
2.5
1.18
1.19
mmol/l
0.41
22
257
7
52
1.35
0.31
1.7
1.3
—
—
—
0
0
55
494
1.12
0.31
1.2
1.6
—
—
—
0
0
7
54
1.30
0.30
1.3
1.6
6.81
7.50
mmol/l
—
7
54
62
563
1.10
0.29
1.6
1.7
—
—
—
0
0
30
345
0.87
0.29
4.5
1.9
1.20
0.90
%
0.70
19
237
8
63
1.27
0.27
3.0
1.5
1.57
2.00
mmol/l
—
8
47
337
3252
1.04
0.27
1.7
1.5
—
—
—
0
0
39
438
0.89
0.27
1.1
1.2
—
—
—
0
0
32
363
0.88
0.26
1.4
1.7
—
—
—
0
0
56
510
1.10
0.26
3.0
3.4
28.29
27.71
mg/l
0.04
37
354
42
378
1.11
0.24
2.3
2.4
12.79
8.52
umol/l
0.21
28
289
11
87
1.26
0.24
1.0
1.0
6.71
8.45
mu/l
0.92
11
75
6
83
0.72
0.24
1.0
1.1
—
—
—
0
0
120
1269
0.94
0.24
1.4
1.5
16.33
21.46
iu/l
1.30
96
1045
14
115
1.22
0.23
1.1
1.2
—
—
—
0
0
124
1176
1.06
0.22
2.7
2.4
—
—
—
0
0
33
295
1.12
0.22
1.3
1.2
—
—
—
0
0
31
276
1.12
0.22
3.5
3.0
18.73
20.51
nmol/l
0.53
31
263
1295
12796
1.02
0.22
4.1
3.9
0.00
0.00
estimate
0.50
202
2751
75
700
1.07
0.21
1.1
1.2
—
—
—
0
0
28
248
1.13
0.21
1.1
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
898.40
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
0.02
—
0
6
0
12
0.00
0.21
0.0
1.0
—
0.06
—
0
12
138
1316
1.05
0.21
1.3
1.2
113.88
124.22
titre
—
8
37
0
13
0.00
0.21
0.0
1.2
—
40.75
—
0
8
0
13
0.00
0.21
0.0
1.2
—
5.05
—
0
8
11
89
1.24
0.20
1.1
1.2
0.92
10.40
u/ml
—
6
65
10
123
0.81
0.20
1.2
1.2
7.40
8.03
mm/h
—
10
123
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
67
717
0.93
0.20
1.6
3.3
1.31
3.40
ratio
1.98
36
423
9
112
0.80
0.20
5.3
5.7
11.56
8.80
%
—
9
112
9
112
0.80
0.20
2.7
2.9
38.67
44.21
%
—
9
112
6
50
1.20
0.19
1.0
1.1
—
—
—
0
0
6
50
1.20
0.19
1.0
1.1
—
—
—
0
0
6
50
1.20
0.19
1.0
1.1
—
—
—
0
0
37
336
1.10
0.19
1.3
1.4
0.20
0.39
nmol/l
—
5
17
166
1594
1.04
0.19
1.3
1.3
—
—
—
0
0
226
2185
1.04
0.19
5.0
4.4
0.87
0.92
%
0.13
82
635
112
1176
0.95
0.19
4.0
3.6
1.02
1.02
ratio
1.43
94
1060
95
900
1.06
0.19
3.2
3.5
264.97
300.39
mg/l
0.29
39
408
484
4939
0.98
0.18
1.8
1.7
35369368.99
24698353.29
pmol/l
0.16
393
4138
6
53
1.13
0.18
1.2
1.0
13.05
34.61
iu/ml
—
6
53
16
137
1.17
0.18
1.1
1.1
1509.62
1495.94
miu/ml
0.02
16
137
28
251
1.12
0.18
1.4
1.6
—
—
—
0
0
127
1214
1.05
0.18
3.5
2.4
—
—
—
0
0
75
706
1.06
0.18
1.2
1.3
104.00
88.87
titre
—
5
71
17
147
1.16
0.18
1.2
1.4
—
71.43
—
0
14
14
119
1.18
0.17
22.9
4.6
56.78
71.83
mg/l
—
9
90
149
1432
1.04
0.17
3.3
2.4
—
—
—
0
0
65
691
0.94
0.17
1.5
1.6
541.80
526.40
mg/l
0.06
60
654
5
68
0.73
0.17
1.8
1.1
—
—
—
0
0
5
68
0.73
0.17
1.8
1.1
—
—
—
0
0
5
68
0.73
0.17
1.2
1.1
15.02
17.03
umol/l
—
5
60
5
68
0.73
0.17
1.8
1.1
—
—
—
0
0
76
803
0.94
0.17
1.8
3.5
37.86
78.98
mg/l
1.29
62
694
26
234
1.11
0.16
1.3
2.2
—
—
—
0
0
76
802
0.95
0.16
1.8
3.5
40.31
54.63
mg/l
1.00
62
692
573
5635
1.02
0.16
1.9
2.1
—
—
—
0
0
159
1535
1.04
0.16
3.2
2.3
—
—
—
0
0
13
111
1.17
0.15
2.5
2.4
1915.38
2028.40
ml
0.15
13
100
492
4834
1.02
0.15
3.1
2.9
540.11
537.51
mosm/kgh2o
0.09
435
4246
214
2081
1.03
0.14
4.8
4.2
0.50
0.73
%
1.72
74
607
9
83
1.08
0.14
1.6
1.8
38.78
436.03
nmol/24h
—
9
83
10
118
0.85
0.14
1.6
1.1
—
—
—
0
0
159
1541
1.03
0.13
3.2
2.2
—
—
—
0
0
8
99
0.81
0.13
1.0
1.1
—
—
—
0
0
22
199
1.11
0.13
1.1
1.2
104.45
109.15
pmol/l
0.23
22
199
206
2007
1.03
0.13
1.9
2.6
66.68
66.47
g/l
0.14
191
1847
227
2215
1.03
0.13
2.1
2.3
12.50
13.04
nmol/l
0.43
199
2022
13
113
1.15
0.13
1.5
1.5
—
—
—
0
0
214
2088
1.03
0.12
5.2
4.4
0.07
0.10
%
0.47
70
539
26
282
0.92
0.12
1.2
1.4
—
—
nmol/l
—
0
0
159
1546
1.03
0.12
3.3
2.3
—
—
—
0
0
15
133
1.13
0.12
3.3
2.1
22.30
27.86
umol/l
1.86
15
125
15
168
0.89
0.11
1.0
1.1
—
—
—
0
0
11
95
1.16
0.11
2.6
1.7
—
—
—
0
0
39
366
1.07
0.11
2.3
1.9
4.54
4.73
mmol/24h
0.15
39
319
207
2114
0.98
0.10
5.4
4.7
0.07
0.27
%
0.63
56
506
12
135
0.89
0.10
1.5
1.7
0.50
0.50
e9/l
0.01
12
135
16
176
0.91
0.09
1.3
1.5
—
—
—
0
0
23
213
1.08
0.09
1.0
1.1
272.13
281.32
mg/l
0.23
23
192
20
184
1.09
0.09
1.5
1.4
36.31
30.55
%
0.27
13
114
173
1766
0.98
0.09
1.3
1.2
166.43
134.01
u/ml
0.50
67
671
156
1525
1.02
0.09
2.2
2.3
—
—
—
0
0
49
512
0.96
0.08
5.5
4.3
2.14
2.53
mmol/l
0.45
36
336
26
243
1.07
0.08
2.3
2.3
—
—
—
0
0
729
7228
1.01
0.08
5.3
5.4
2.71
3.62
ug/l
0.53
638
6516
66
684
0.96
0.08
14.3
10.5
—
—
—
0
0
232
2281
1.02
0.08
4.1
4.3
15.73
17.25
ug/l
0.08
180
1866
21
226
0.93
0.08
1.2
1.1
11.00
15.64
u/ml
—
10
84
7
67
1.04
0.08
3.0
2.3
20.17
15.83
umol/l
—
7
67
6
75
0.80
0.07
1.0
1.0
—
—
—
0
0
6
75
0.80
0.07
1.0
1.0
6.80
7.00
kpa
—
6
63
6
75
0.80
0.07
1.0
1.0
—
-2.17
—
0
15
6
75
0.80
0.07
1.0
1.0
3.17
3.32
kpa
—
6
63
13
143
0.91
0.07
1.5
1.2
—
—
—
0
0
8
76
1.05
0.07
1.1
2.1
—
—
—
0
0
7
81
0.86
0.07
1.0
1.0
—
—
—
0
0
8
93
0.86
0.06
1.0
1.2
—
0.10
—
0
9
27
285
0.95
0.06
4.2
1.9
39.69
23.35
ug/l
0.39
27
280
77
749
1.03
0.06
1.5
1.5
65.27
59.76
ug/l
0.47
63
629
26
246
1.06
0.06
1.1
1.1
—
—
—
0
0
111
1129
0.98
0.05
1.6
1.7
0.20
0.31
mg/l
2.32
49
544
108
1061
1.02
0.05
4.5
3.2
—
—
—
0
0
34
327
1.04
0.04
1.3
1.4
0.57
6.04
nmol/l
0.50
34
314
60
615
0.97
0.04
1.7
1.7
1219.20
899.06
e6/l
0.18
46
482
19
201
0.94
0.04
1.5
1.7
7.63
7.49
mmol/l
0.13
19
194
31
298
1.04
0.04
1.4
1.4
288.49
352.22
pmol/l
0.44
25
253
931
9274
1.01
0.04
1.9
1.9
1.37
1.35
mmol/l
0.27
769
7916
18
170
1.06
0.04
20.8
20.9
1205.72
1410.19
nmol/l
0.58
18
165
43
418
1.03
0.03
1.5
1.2
—
—
—
0
0
46
471
0.98
0.03
3.5
3.6
2300.20
896.30
u/ml
0.33
39
439
137
1356
1.01
0.02
1.2
1.2
—
—
—
0
0
26
268
0.97
0.02
1.6
1.4
19265.50
86974.85
e6/l
1.52
12
147
25
257
0.97
0.01
1.5
1.4
—
—
—
0
0
60
607
0.99
0.01
1.6
1.7
44.71
25.06
e6/l
0.20
45
454
50
493
1.01
0.01
1.4
1.4
58.32
63.34
mmol/l
0.33
37
396
23
236
0.97
0.00
2.6
2.3
—
—
—
0
0
1098
10984
1.00
0.00
12.1
11.3
0.00
0.00
e9/l
0.55
873
8904
14
138
1.01
0.00
1.3
1.7
—
—
—
0
0
11
105
1.05
0.00
1.5
1.3
147.55
166.26
mmol/24h
0.39
11
105
12
118
1.02
0.00
5.2
1.3
184.17
343.15
u/l
0.76
12
107
18
175
1.03
0.00
1.1
1.3
166.74
178.06
pmol/l
0.16
18
175
23
230
1.00
0.00
1.4
1.2
—
—
—
0
0
109
1089
1.00
0.00
2.4
2.0
—
—
—
0
0
41
410
1.00
0.00
1.8
1.7
—
—
—
0
0
110
1104
1.00
0.00
1.1
1.1
—
—
—
0
0
34
340
1.00
0.00
1.9
1.8
—
—
—
0
0
86
855
1.01
0.00
1.6
2.4
9.89
10.35
g/l
0.64
80
767
31
306
1.01
0.00
1.5
1.4
1851.81
4487.98
e6/l
0.44
21
214
31
310
1.00
0.00
1.5
1.5
285.95
280.24
mosm/kgh2o
0.56
20
223
55
555
0.99
0.00
5.5
3.7
—
—
—
0
0
25
248
1.01
0.00
1.6
1.4
—
—
—
0
0
25
252
0.99
0.00
1.2
1.1
—
—
—
0
0
57
565
1.01
0.00
1.1
1.1
—
—
—
0
0
16
161
0.99
0.00
1.3
2.3
182.54
834.75
pmol/l
—
5
24
5
49
1.02
0.00
1.4
1.9
3.82
4.77
nmol/l
—
5
49
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
8.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
79
0.89
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
3.74
—
0
5
0
7
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1745.20
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
-0.00
1.1
1.9
0.00
0.03
estimate
—
8
87
0
5
0.00
-0.00
0.0
2.4
—
1.50
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
6.80
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
85
0.94
-0.00
1.3
1.7
37.97
40.43
g/l
—
8
85
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_CHRON_SUPOTITIS and mortality.

Females

Parameter HR [95% CI] p-value
H8_CHRON_SUPOTITIS 1.218 [1.07, 1.39] 0.003
Birth year 0.994 [0.99, 1.0] 0.171

During the follow-up period (1.1.1998 — 31.12.2019), 566 out of 6742 females with H8_CHRON_SUPOTITIS died.

Males

Parameter HR [95% CI] p-value
H8_CHRON_SUPOTITIS 1.217 [1.06, 1.4] 0.006
Birth year 0.985 [0.98, 0.99] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 673 out of 8885 males with H8_CHRON_SUPOTITIS died.

Mortality risk

Mortality risk for people of age

years, who have H8_CHRON_SUPOTITIS.

N-year risk Females Males
1 0.116% 0.167%
5 0.661% 1.295%
10 1.752% 3.212%
15 3.385% 6.503%
20 6.301% 10.844%

Relationships between endpoints

Index endpoint: H8_CHRON_SUPOTITIS – Chronic suppurative otitis media

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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