Generalized skin eruption due to drugs and medicaments

GENERALI_SKIN_ERUPT_DRUGS_MEDICAM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L27.0#

1 out of 7 registries used, show all original rules.

1776

4. Check minimum number of events

None

1776

5. Include endpoints

None

1776

6. Filter based on genotype QC (FinnGen only)

1564

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11054 6550 4445
Only index persons 9672 5844 3828
Unadjusted period prevalence (%)
Whole population 0.16 0.19 0.12
Only index persons 0.19 0.21 0.15
Median age at first event (years)
Whole population 49.28 52.61 44.11
Only index persons 48.96 51.80 44.62

-FinnGen-

Key figures

All Female Male
Number of individuals 1564 1017 547
Unadjusted period prevalence (%) 0.32 0.36 0.25
Median age at first event (years) 56.47 53.26 62.45

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1606
Matched controls
16060
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
4503599627370496.0
307.7
1603
27
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
6.2
195.9
401
818
H02AB06
ATC
prednisolone; systemic
3.9
144.5
1088
5638
XQ820
NOMESCO Finland
Exposure to medicinal substance
56.8
143.3
81
15
XQ800
NOMESCO Finland
Prick test
5.2
122.7
288
649
XQ899
NOMESCO Finland
Other assessment of skin
31.4
114.5
75
25
XQ802
NOMESCO Finland
Epicutan test
6.8
112.6
190
313
L50.0
ICD-10 Finland
Allergic urticaria
8.2
106.7
148
196
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.0
86.3
277
787
R06AE07
ATC
cetirizine; oral
2.8
85.7
935
5377
XQ801
NOMESCO Finland
Intracutantest
21.1
83.2
63
31
J01FF01
ATC
clindamycin; systemic
2.8
82.0
603
2822
T78.4
ICD-10 Finland
Allergy, unspecified
5.3
80.1
172
354
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.9
80.0
517
2255
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
8.4
79.5
107
136
D07AC01
ATC
betamethasone; topical
2.6
73.5
752
4096
E0000UV, ,
ATC
2.5
72.8
877
5150
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
9.3
68.4
84
95
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
67.6
914
5592
R50.9
ICD-10 Finland
Fever, unspecified
2.9
66.5
387
1576
D07AB08
ATC
desonide; topical
3.2
62.8
289
1027
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.3
62.0
272
939
L50.9
ICD-10 Finland
Urticaria, unspecified
4.9
59.8
140
309
J01MA12
ATC
levofloxacin; systemic
2.6
51.6
380
1722
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
13.9
49.5
46
34
ZX108
NOMESCO Finland
Inhalation
12.2
44.7
45
38
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.6
44.5
300
1295
D07AA02
ATC
hydrocortisone; topical
2.5
43.8
326
1475
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.8
42.9
136
377
D07AB02
ATC
hydrocortisone butyrate; topical
2.1
42.2
575
3346
A46
ICD-10 Finland
Erysipelas
2.6
41.7
292
1280
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
40.4
628
3823
E000001, ,
ATC
2.3
40.3
413
2141
C01CA24
ATC
epinephrine; parenteral
3.2
40.1
173
585
TQW80
NOMESCO Finland
Local dermatologic skincare
5.2
40.1
84
168
L04AX01
ATC
azathioprine; systemic
3.9
37.6
116
315
P01BA02
ATC
hydroxychloroquine; oral
2.9
37.3
188
694
L04AX03
ATC
methotrexate; systemic
2.7
36.0
215
868
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
35.2
236
1008
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
35.0
417
2278
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.7
34.4
114
325
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.4
33.3
125
387
L27.1
ICD-10 Finland
Localized skin eruption due to drugs and medicaments
11.6
31.9
33
29
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
31.4
461
2702
L04AD01
ATC
ciclosporin; systemic
5.4
30.9
62
119
JN4AD
NOMESCO Finland
Body CT examination
2.4
30.5
225
1002
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
30.2
416
2381
A02BC02
ATC
pantoprazole; systemic
1.9
30.1
1117
8755
J01MA14
ATC
moxifloxacin; systemic
2.7
30.1
181
731
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
29.8
506
3107
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.4
29.6
112
348
N03AG01
ATC
valproic acid; systemic, rectal
3.0
29.3
136
478
J01MA02
ATC
ciprofloxacin; systemic
1.8
29.2
636
4221
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.2
28.0
116
381
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.8
27.9
86
233
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
27.8
223
1029
D07AD01
ATC
clobetasol; topical
2.1
27.5
304
1599
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.2
26.9
72
176
N02AA05
ATC
oxycodone; systemic
2.0
26.7
328
1792
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.7
26.7
154
608
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
26.5
291
1525
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
4.6
26.3
64
145
XW000
NOMESCO Finland
Bone marrow biopsy
3.5
26.3
94
282
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
26.1
319
1739
H02AB04
ATC
methylprednisolone; systemic
2.2
25.9
262
1329
D07AC13
ATC
mometasone; topical
1.8
25.3
496
3158
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.4
25.1
91
275
J01DB01
ATC
cefalexin; oral
2.1
25.0
1344
11467
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.9
24.8
389
2306
H02AB02
ATC
dexamethasone; systemic
2.2
24.7
220
1059
N02AX02
ATC
tramadol; systemic, rectal
1.7
24.5
683
4807
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.3
24.4
206
969
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.7
24.3
142
564
L04AA06
ATC
mycophenolic acid; systemic
4.7
24.2
56
122
C03CA01
ATC
furosemide; systemic
1.8
23.8
479
3063
M04AA01
ATC
allopurinol; systemic
2.2
23.8
217
1054
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
23.6
232
1162
A04AA01
ATC
ondansetron; systemic, rectal
2.4
23.5
170
747
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
23.4
392
2367
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
23.4
200
946
ZX120
NOMESCO Finland
Intravenous
2.3
22.9
184
847
N03AX16
ATC
[U] pregabalin
1.9
22.4
377
2278
L27.2
ICD-10 Finland
Dermatitis due to ingested food
5.6
22.3
42
76
J01XX08
ATC
linezolid; systemic
8.4
22.3
29
35
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.1
22.1
245
1282
H02AB09
ATC
hydrocortisone; systemic
4.0
22.1
64
166
H02AB07
ATC
prednisone; oral
2.1
22.0
242
1264
E000003, ,
ATC
3.0
21.9
98
337
L50.8
ICD-10 Finland
Other urticaria
4.4
21.6
54
125
GD1AD
NOMESCO Finland
Thorax CT examination
2.6
21.6
127
506
XQ848
NOMESCO Finland
Dermatological photography
3.7
21.4
70
198
E000006, ,
ATC
2.5
20.7
137
577
N03AX14
ATC
levetiracetam; systemic
3.7
20.7
67
188
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.5
20.6
50
113
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.5
20.5
134
561
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.5
20.3
132
552
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.9
19.9
60
160
D02AX
ATC
Other emollients and protectives
3.3
19.9
76
238
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.5
19.6
134
573
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
19.6
169
801
R06AX27
ATC
desloratadine; oral
1.7
19.5
500
3388
J01DA01
ATC
[U] cefalexin
1.6
19.5
969
7750
D07XC01
ATC
betamethasone; topical
2.1
19.4
202
1031
WW500
NOMESCO Finland
Blood transfusion
2.9
18.8
88
310
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.8
18.8
42
89
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.5
18.5
63
183
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
18.5
603
4334
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
4.1
18.4
51
128
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
18.4
162
773
L01BA01
ATC
methotrexate; systemic
3.1
18.4
77
255
NF1AA
NOMESCO Finland
Hip X-ray examination
2.2
18.3
164
789
L04AX04
ATC
lenalidomide; oral
7.5
18.3
26
35
N03AF02
ATC
oxcarbazepine; oral
3.2
18.2
73
235
SPAT1255
SPAT
Intravenous administration of medicine
2.5
18.1
117
488
N03AF01
ATC
carbamazepine; oral, rectal
2.7
18.0
101
392
J01FA06
ATC
roxithromycin; oral
1.6
17.8
614
4462
S88
ICPC
Dermatitis contact/allergic
3.8
17.7
55
150
JN4BD
NOMESCO Finland
Extensive body CT
2.1
17.7
170
840
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
17.6
372
2383
P01AB01
ATC
metronidazole; oral, rectal
1.6
17.5
632
4640
E000002, ,
ATC
2.0
17.3
201
1066
A07EC01
ATC
sulfasalazine; oral, rectal
2.3
17.2
141
653
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
6.5
17.1
28
44
SPAT1263
SPAT
Sampling
1.6
17.0
666
4973
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.6
16.9
56
160
N03AX09
ATC
lamotrigine; oral
2.6
16.8
102
412
D05BB02
ATC
acitretin; oral
3.8
16.7
50
133
L26
ICD-10 Finland
Exfoliative dermatitis
35.4
16.7
21
6
N02BE01
ATC
paracetamol; systemic, rectal
1.9
16.7
1412
12683
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2.8
16.5
87
327
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.0
16.4
73
250
J05AB11
ATC
valaciclovir; oral
1.8
16.4
254
1481
J01AA02
ATC
doxycycline; systemic
1.6
16.4
1179
10083
ZYC01
NOMESCO Finland
Remote contact by phone
2.3
16.4
123
548
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.9
16.3
222
1242
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.4
16.1
113
489
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
16.0
671
5069
A92
ICPC
Allergy/allergic reaction NOS
2.9
15.9
74
260
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
15.8
169
869
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
15.7
318
2006
L03AA02
ATC
filgrastim; parenteral
3.1
15.6
64
209
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.1
15.6
151
748
WW200
NOMESCO Finland
Immunization
3.5
15.6
54
159
L04AA01
ATC
[U] ciclosporin
5.0
15.5
33
67
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.1
15.5
163
833
R60.0
ICD-10 Finland
Localized oedema
1.9
15.5
208
1158
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
15.5
414
2810
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.0
15.4
43
109
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.0
15.3
170
886
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.1
15.2
65
218
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
20.3
15.1
22
11
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.1
15.0
63
209
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.8
15.0
45
120
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
4.6
15.0
35
77
A03
ICPC
Fever
1.7
14.9
309
1959
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
14.9
604
4510
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
14.9
227
1316
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.4
14.8
101
431
J02AC01
ATC
fluconazole; systemic
1.5
14.8
616
4623
A04AA02
ATC
granisetron; systemic, transdermal
2.3
14.7
113
509
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
2.8
14.7
74
272
R01AD08
ATC
fluticasone; nasal
1.6
14.6
441
3076
A41.9
ICD-10 Finland
Sepsis, unspecified
2.9
14.5
69
246
J05AB01
ATC
aciclovir; systemic
1.6
14.4
361
2403
Z51.5
ICD-10 Finland
Palliative care
2.1
14.4
143
714
N03AX12
ATC
[U] gabapentin; oral
1.8
14.4
253
1529
T88.6
ICD-10 Finland
Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
15.5
14.4
23
15
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
14.4
215
1238
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
14.3
168
894
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.7
14.2
78
300
SPAT1254
SPAT
Administration of medicine
1.8
14.2
248
1497
153
Kela drug reimbursment
Lenalidomid
6.5
14.1
23
36
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.1
14.0
59
196
AA1AD
NOMESCO Finland
CT of head and brain
1.6
14.0
438
3075
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.0
14.0
63
218
L51.9
ICD-10 Finland
Erythema multiforme, unspecified
15.9
13.9
22
14
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
13.9
473
3386
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
13.8
235
1406
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
13.8
254
1555
R06.0
ICD-10 Finland
Dyspnoea
1.6
13.8
431
3024
J01FA09
ATC
clarithromycin; systemic
1.6
13.8
480
3452
UJF32
NOMESCO Finland
Coloscopy
1.6
13.7
393
2703
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
4.2
13.5
36
88
B01AB05
ATC
enoxaparin; parenteral
1.6
13.5
469
3370
L27.9
ICD-10 Finland
Dermatitis due to unspecified substance taken internally
141.2
13.5
14
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.3
13.4
106
483
XG410
NOMESCO Finland
Flow-volume spirometry
2.6
13.4
75
292
WZC30
NOMESCO Finland
Teaching
1.7
13.3
260
1618
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.7
13.3
73
281
L30.3
ICD-10 Finland
Infective dermatitis
2.8
13.3
66
241
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
2.9
13.2
61
214
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
13.1
656
5082
A02BC05
ATC
esomeprazole; systemic
1.5
13.1
603
4595
N03AX18
ATC
lacosamide; systemic
6.0
13.1
23
39
A10AB05
ATC
insulin aspart; parenteral
2.1
13.0
128
638
ZXD05
NOMESCO Finland
Urgent procedure
1.5
13.0
455
3271
C91.4
ICD-10 Finland
Hairy-cell leukaemia
50.4
12.9
15
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
12.8
385
2671
J01FA10
ATC
azithromycin; systemic
1.5
12.8
902
7466
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
3.3
12.8
49
154
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.7
12.8
40
110
S76
ICPC
Skin infection other
2.3
12.8
94
416
TGC00
NOMESCO Finland
Bronchial lavation
3.2
12.7
51
165
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.9
12.6
58
203
9940/3-C42.1
ICD-O-3
Hairy cell leukemia, NOS, of bone marrow
70.4
12.6
14
*
R03BA02
ATC
budesonide; inhalant
1.7
12.4
292
1906
R06AE09
ATC
levocetirizine; oral
1.7
12.4
235
1450
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
12.3
297
1951
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.3
12.3
96
436
C90.0
ICD-10 Finland
Multiple myeloma
4.5
12.2
29
65
N05BA09
ATC
clobazam; oral
6.1
12.1
21
35
D02AE01
ATC
carbamide; topical
2.2
12.1
107
512
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
2.4
12.0
80
338
S97
ICPC
Chronic ulcer skin
2.2
11.9
102
481
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
11.9
175
1002
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
11.7
287
1892
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
4.6
11.7
27
59
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
11.6
193
1145
R03AC02
ATC
salbutamol; inhalant
1.4
11.6
858
7112
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
11.6
639
5014
D70.82
ICD-10 Finland
Drug-induced neutropenia
3.7
11.5
36
99
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.5
11.5
73
302
L50.1
ICD-10 Finland
Idiopathic urticaria
5.7
11.5
21
37
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.7
11.5
62
237
L04AB04
ATC
adalimumab; parenteral
3.1
11.5
46
149
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
11.4
804
6594
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
3.4
11.4
41
124
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
3.5
11.3
38
110
D11AH01
ATC
tacrolimus; topical
4.6
11.2
26
57
L51.0
ICD-10 Finland
Nonbullous erythema multiforme
17.2
11.2
17
10
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.0
11.1
50
173
M79.6
ICD-10 Finland
Pain in limb
1.4
11.1
677
5401
N05CF01
ATC
zopiclone; oral
1.5
11.1
464
3444
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
10.1
11.0
21
21
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
4.4
11.0
27
62
R01AD09
ATC
mometasone; nasal
1.4
11.0
691
5538
127
Kela drug reimbursment
Transplant complication
3.7
11.0
34
93
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
4.9
11.0
24
50
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.3
10.9
79
348
SPAT1153
SPAT
Removal of sutures
1.5
10.8
450
3335
M05BA04
ATC
alendronic acid; oral
1.9
10.7
136
741
M54.5
ICD-10 Finland
Low back pain
1.5
10.7
559
4322
R60.9
ICD-10 Finland
Oedema, unspecified
2.2
10.6
95
456
Z88.1
ICD-10 Finland
Personal history of allergy to other antibiotic agents
60.4
10.6
12
*
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
10.6
191
1160
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
3.7
10.5
33
91
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.9
10.5
125
668
L04AA13
ATC
[U] leflunomide
3.0
10.4
44
147
M05BX04
ATC
denosumab; parenteral
2.1
10.4
101
501
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
10.4
303
2078
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.2
10.3
92
441
J45.1
ICD-10 Finland
Nonallergic asthma
2.0
10.3
117
614
N02BF02
ATC
pregabalin; oral
2.0
10.3
110
565
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.5
10.3
62
251
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.1
10.2
96
470
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
10.2
296
2027
R06AX22
ATC
ebastine; oral
1.6
10.2
259
1720
D05AX52
ATC
calcipotriol, combinations; topical
2.3
10.1
78
353
C07AB07
ATC
bisoprolol; oral
1.4
10.1
673
5427
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
3.8
10.1
30
80
L40.1
ICD-10 Finland
Generalized pustular psoriasis
40.3
10.0
12
*
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
10.0
177
1070
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
9.9
141
797
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.9
9.9
133
739
L03.9
ICD-10 Finland
Cellulitis, unspecified
3.3
9.9
37
115
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.5
9.8
61
250
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
5.2
9.8
20
39
D07BC01
ATC
betamethasone and antiseptics; topical
1.7
9.8
171
1027
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
4.0
9.8
27
68
A02BC03
ATC
lansoprazole; oral
1.5
9.8
410
3031
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.1
9.7
91
445
R03DC03
ATC
montelukast; oral
1.6
9.7
259
1737
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
4.1
9.7
26
64
L88
ICPC
Rheumatoid/seropositive arthritis
2.4
9.7
68
295
318
Kela drug reimbursment
Teriparatide
9.1
9.5
19
21
H05AA02
ATC
teriparatide; parenteral
10.1
9.5
18
18
B01AB10
ATC
tinzaparin; parenteral
1.7
9.5
167
1006
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.1
9.4
85
410
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
9.4
582
4617
SPAT1301
SPAT
No procedures
1.4
9.4
462
3518
ZX112
NOMESCO Finland
Subcutaneous
2.9
9.4
43
151
N18.8
ICD-10 Finland
Other chronic renal failure
3.2
9.4
37
119
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.8
9.4
150
880
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.1
9.2
37
120
J01DA09
ATC
[U] cefadroxil
1.5
9.2
383
2822
A07AA09
ATC
vancomycin; oral
3.7
9.2
28
76
R11
ICD-10 Finland
Nausea and vomiting
1.8
9.2
148
870
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.0
9.1
93
470
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.3
9.1
67
297
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.6
9.1
51
199
A02BC01
ATC
omeprazole; systemic
1.5
9.1
389
2881
TK800
NOMESCO Finland
Hemodialysis
3.2
9.1
35
111
J01CE08
ATC
benzathine benzylpenicillin; parenteral
4.8
9.1
20
42
R51.80
ICD-10 Finland
Headache
1.6
9.1
256
1739
A07AA02
ATC
nystatin; oral
2.1
9.0
90
451
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
36.9
9.0
11
*
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
9.0
155
928
S18
ICPC
Laceration/cut
1.4
9.0
699
5750
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
9.0
101
529
A10AC01
ATC
insulin (human); parenteral
1.9
9.0
117
644
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
3.7
8.9
27
73
L50
ICD-10 Finland
Urticaria
2.9
8.9
40
139
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
8.9
181
1135
N06AX21
ATC
duloxetine; oral
1.7
8.9
184
1159
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
4.4
8.9
22
51
L04AC05
ATC
ustekinumab; parenteral
8.0
8.9
19
24
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
3.6
8.8
28
78
SPAT1229
SPAT
Assessment of need for aid
1.9
8.8
109
589
UJK02
NOMESCO Finland
ERCP
2.8
8.8
44
162
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.3
8.8
65
289
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
3.0
8.8
37
124
N05BA04
ATC
oxazepam; oral
1.5
8.8
387
2882
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
2.7
8.7
44
163
L30.8
ICD-10 Finland
Other specified dermatitis
2.5
8.7
51
204
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
8.7
127
725
501
Kela drug reimbursment
Cow's milk and / or soy protein allergy in young children
4.3
8.7
22
52
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
8.7
290
2043
L40.9
ICD-10 Finland
Psoriasis, unspecified
3.5
8.7
29
84
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
8.6
218
1443
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
3.6
8.6
27
75
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.1
8.5
80
392
D07CC01
ATC
betamethasone and antibiotics; topical
1.6
8.5
183
1163
R02
ICPC
Shortness of breath/dyspnoea
1.6
8.5
204
1332
WX892
NOMESCO Finland
Monitored bed care
1.9
8.5
113
627
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.9
8.4
24
62
L30.0
ICD-10 Finland
Nummular dermatitis
2.3
8.4
61
269
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
8.4
275
1927
M79.1
ICD-10 Finland
Myalgia
1.6
8.4
234
1583
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
8.4
312
2245
R03AC03
ATC
terbutaline; inhalant
1.6
8.4
202
1321
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
4.5
8.4
20
45
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.3
8.4
64
289
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
8.4
245
1676
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
4.9
8.4
18
37
L20.0
ICD-10 Finland
Besnier prurigo
1.8
8.3
132
772
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.9
8.2
106
581
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
8.2
422
3224
SPAT1325
SPAT
Vaccination
1.4
8.2
486
3806
XX3DW
NOMESCO Finland
Time consuming IT work
1.7
8.2
155
952
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
8.2
162
1008
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
4.4
8.2
20
46
SCA03
NOMESCO Finland
Preventive oral health care, extensive
2.0
8.2
81
406
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
8.2
95
504
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
4.8
8.1
18
38
D05AX03
ATC
calcitriol; topical
3.8
8.1
24
64
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.9
8.1
97
520
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
8.1
615
5017
D05AX02
ATC
calcipotriol; topical
2.4
8.1
52
218
183
Kela drug reimbursment
Lamotrigin and topiramate
4.2
8.0
21
51
NH3EA
NOMESCO Finland
Feet X-ray examination with load
3.0
8.0
35
120
N03AB02
ATC
phenytoin; systemic
3.9
8.0
23
60
L40.5
ICD-10 Finland
Arthropathic psoriasis
3.2
8.0
31
99
R53
ICD-10 Finland
Malaise and fatigue
1.4
8.0
388
2935
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.7
8.0
142
859
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
2.7
8.0
40
148
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.5
7.9
49
201
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
4.3
7.9
20
47
L28
ICPC
Limited function/disability (L)
1.5
7.9
271
1915
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.7
7.9
136
815
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.9
7.9
95
510
B03XA02
ATC
darbepoetin alfa; parenteral
2.8
7.9
37
132
S70
ICPC
Herpes zoster
2.5
7.9
47
190
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.7
7.9
143
870
ZY010
NOMESCO Finland
Hospital outpatient
2.0
7.8
89
468
C08CA01
ATC
amlodipine; oral
1.4
7.7
512
4078
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
7.7
223
1520
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.4
7.7
465
3647
J46
ICD-10 Finland
Status asthmaticus
2.5
7.7
47
192
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
7.7
150
931
S06
ICPC
Rash localized
2.0
7.6
86
451
J01FA01
ATC
erythromycin; systemic
1.6
7.6
198
1317
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
7.6
158
995
WX002
NOMESCO Finland
Sedation and analgesia
1.5
7.6
269
1913
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
2.9
7.6
34
118
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
18.4
7.6
11
6
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
6.2
7.5
19
31
J20
ICD-10 Finland
Acute bronchitis
1.6
7.5
157
990
WZA10
NOMESCO Finland
Extensive medical or dental certificate
3.3
7.5
28
87
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
2.9
7.5
34
119
M13.9
ICD-10 Finland
Arthritis, unspecified
1.8
7.5
109
622
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
4.3
7.5
19
45
D11AH02
ATC
pimecrolimus; topical
7.1
7.5
17
24
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
7.5
249
1750
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
2.3
7.5
55
245
R06AX13
ATC
loratadine; oral
1.5
7.5
222
1523
L30
ICD-10 Finland
Other dermatitis
2.5
7.5
44
177
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.4
7.4
51
220
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.9
7.4
88
470
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
7.4
200
1342
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
7.4
196
1310
X57
ICD-10 Finland
Unspecified privation
2.6
7.4
40
154
ZXX04
NOMESCO Finland
Extent of procedure, 4 units
7.7
7.4
16
21
B34.9
ICD-10 Finland
Viral infection, unspecified
2.3
7.4
52
227
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
2.6
7.4
41
160
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
7.4
395
3033
F31.3
ICD-10 Finland
Bipolar affective disorder, current episode mild or moderate depression
4.0
7.4
20
50
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.3
7.3
55
247
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
7.3
1091
9792
J01EA01
ATC
trimethoprim; systemic
1.4
7.3
381
2914
EMB30
NOMESCO Finland
Adenotomy
2.3
7.2
52
229
Z3231
NOMESCO Finland
Registered nurse
1.4
7.2
385
2952
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.4
7.2
47
198
6960A
ICD-9 Finland
Psoriasis and similar disorders, Psoriatic arthropathy
15.8
7.2
11
7
SPAT1260
SPAT
Consultation of another employee
1.5
7.2
245
1727
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.1
7.2
63
301
D69.0
ICD-10 Finland
Allergic purpura
4.5
7.2
17
38
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
7.2
188
1253
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
7.2
181
1196
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
4.0
7.2
20
51
S01
ICPC
Pain/tenderness of skin
2.0
7.2
72
363
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.3
7.2
54
243
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
7.1
817
7039
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.8
7.1
35
128
XG466
NOMESCO Finland
Sleep oxymetry
2.4
7.1
45
187
D70.89
ICD-10 Finland
Neutropenic splenomegaly
3.5
7.1
24
70
J04AB02
ATC
rifampicin; systemic
3.5
7.1
24
70
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
3.3
7.1
26
80
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.3
7.1
54
244
M25.5
ICD-10 Finland
Pain in joint
1.4
7.1
484
3863
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
7.1
397
3070
A07EA06
ATC
budesonide; oral, local oral
2.2
7.0
60
284
H25.8
ICD-10 Finland
Other senile cataract
1.7
7.0
144
904
L04AD02
ATC
tacrolimus; systemic
3.6
7.0
22
61
OAB50, ,
SPAT
1.7
7.0
120
718
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
3.5
7.0
23
66
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.5
7.0
23
66
R42
ICD-10 Finland
Dizziness and giddiness
1.4
7.0
326
2441
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.3
7.0
50
220
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
3.3
7.0
25
76
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
6.9
148
939
J47
ICD-10 Finland
Bronchiectasis
2.8
6.9
33
119
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
6.9
103
592
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
5.9
6.9
18
31
N05BB01
ATC
hydroxyzine; systemic
1.8
6.9
94
526
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.5
6.9
42
172
K30
ICD-10 Finland
Functional dyspepsia
1.6
6.9
167
1094
JN6AD
NOMESCO Finland
CT of torso and neck
2.9
6.9
30
103
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.1
6.8
59
281
WX882
NOMESCO Finland
High dependency care
2.3
6.8
49
216
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
6.8
211
1459
B01AC04
ATC
clopidogrel; oral
1.5
6.8
208
1434
WVA20
NOMESCO Finland
Medicine administration
2.3
6.8
48
210
N05BA01
ATC
diazepam; systemic, rectal
1.6
6.8
182
1219
K59.1
ICD-10 Finland
Functional diarrhoea
1.9
6.8
89
492
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.2
6.8
56
262
H66.9
ICD-10 Finland
Otitis media, unspecified
1.7
6.8
110
649
G47.3
ICD-10 Finland
Sleep apnoea
1.4
6.8
295
2182
B02.9
ICD-10 Finland
Zoster without complication
1.8
6.8
100
574
L51.1
ICD-10 Finland
Bullous erythema multiforme
16.8
6.7
10
6
M03BX02
ATC
tizanidine; oral
1.3
6.7
871
7609
M05BA07
ATC
risedronic acid; oral
2.3
6.7
48
211
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
3.5
6.7
22
63
N02BF01
ATC
gabapentin; oral
1.6
6.7
152
979
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
2.9
6.7
31
110
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.1
6.7
60
290
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
6.7
771
6628
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.4
6.7
45
193
B35.3
ICD-10 Finland
Tinea pedis
2.0
6.7
67
338
M05BB03
ATC
alendronic acid and colecalciferol; oral
2.6
6.6
37
145
J32.4
ICD-10 Finland
Chronic pansinusitis
3.1
6.6
27
89
Z71.8
ICD-10 Finland
Other specified counselling
1.3
6.6
513
4166
J01FA15
ATC
telithromycin; oral
1.7
6.6
131
816
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
2.2
6.6
52
239
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
12.3
6.6
11
9
T78.3
ICD-10 Finland
Angioneurotic oedema
3.2
6.6
25
79
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.7
6.6
118
716
130
Kela drug reimbursment
Malignant tumour
1.7
6.6
113
678
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
4.2
6.6
17
41
L04AB01
ATC
etanercept; parenteral
3.0
6.6
28
95
UDM02
NOMESCO Finland
Sinoscopy
2.5
6.5
38
152
N06AX16
ATC
venlafaxine; oral
1.5
6.5
207
1438
H01
ICPC
Ear pain/earache
1.5
6.5
186
1263
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.0
6.5
66
334
A28
ICPC
Limited function/disability NOS
1.5
6.5
248
1787
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
1.8
6.5
98
566
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
2.9
6.5
29
101
SPAT1262
SPAT
Handing over of treatment supplies
1.5
6.5
223
1576
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.0
6.5
68
349
R01AD12
ATC
fluticasone furoate; nasal
1.3
6.4
452
3614
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
2.7
6.4
33
124
L03AA13
ATC
pegfilgrastim; parenteral
2.0
6.4
70
364
WW300
NOMESCO Finland
Transfer of autologic stem cells
7.4
6.4
14
19
S29
ICPC
Skin symptom/complaint other
1.4
6.4
295
2202
SPAT1312
SPAT
General health counselling
1.3
6.4
457
3664
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.9
6.4
74
393
J01DC02
ATC
cefuroxime; systemic
1.9
6.3
79
430
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
2.7
6.3
33
125
K07
ICPC
Swollen ankles/oedema
1.9
6.3
72
380
N03AE01
ATC
clonazepam; systemic
1.9
6.3
77
416
319
Kela drug reimbursment
Adalimumab, brodalumab, certolizumab pegol, etanercept, guselkumab, infliximab, ixekizumab, risankizumab, sekukinumab and ustekinumab (skin psoriasis)
6.0
6.3
16
27
A04
ICPC
Weakness/tiredness general
1.4
6.3
247
1790
B99
ICD-10 Finland
Other and unspecified infectious diseases
2.7
6.3
32
120
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
3.9
6.3
18
47
M01AH02
ATC
rofecoxib; oral
1.5
6.3
168
1126
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.8
6.2
94
544
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
2.4
6.2
42
181
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
6.2
279
2075
329
Kela drug reimbursment
Lenalidomide
6.3
6.2
15
24
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
3.2
6.2
23
72
128
Kela drug reimbursment
Cancers of female genital organs
2.6
6.2
33
127
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.5
6.1
184
1263
V03AE01
ATC
polystyrene sulfonate; oral
3.4
6.1
21
62
N06AA09
ATC
amitriptyline; systemic
1.6
6.1
126
792
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
6.1
312
2368
F43.20
ICD-10 Finland
Adaptation disorder with short-term depression
3.0
6.1
26
88
A01AB09
ATC
miconazole; local oral
1.7
6.1
121
754
R03BA05
ATC
fluticasone; inhalant
1.4
6.1
260
1913
C03AA03
ATC
hydrochlorothiazide; oral
1.7
6.1
118
731
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
3.1
6.1
24
78
134
Kela drug reimbursment
General erythroderma
6.7
6.0
14
21
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
3.2
6.0
23
73
R4180
NOMESCO Finland
Podiatric therapy
3.3
6.0
22
68
K50.1
ICD-10 Finland
Crohn disease of large intestine
3.4
6.0
21
63

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
60
17
36.63
95.88
1.1
1.1
0.07
0.02
u/ml
0.66
60
17
723
3774
2.67
78.50
7.0
4.3
—
—
—
0
0
214
603
3.94
66.70
1.4
1.2
—
—
—
0
0
821
4885
2.39
63.27
12.9
6.4
—
—
—
0
0
314
1175
3.08
62.47
4.6
3.0
10.12
10.58
g/l
0.88
300
1085
1089
7370
2.48
62.16
12.9
6.4
0.58
0.57
e9/l
0.61
1014
6319
1089
7384
2.47
61.67
13.0
6.4
0.04
0.04
e9/l
0.05
1011
6336
1108
7615
2.47
60.17
13.5
6.7
0.21
0.19
e9/l
1.74
1039
6632
1099
7548
2.44
59.40
13.1
6.5
1.95
1.92
e9/l
0.10
1039
6640
1155
8249
2.42
54.92
18.6
9.6
4.22
4.08
e9/l
1.31
1074
7182
255
917
3.12
53.85
2.7
1.9
1.16
1.45
g/l
1.14
235
850
1003
6802
2.26
53.05
13.8
6.7
8.55
8.71
%
0.95
962
6384
997
6796
2.23
51.34
13.7
6.6
3.03
2.83
%
1.33
958
6372
1049
7304
2.26
51.16
11.3
6.5
10.61
11.30
umol/l
0.90
1014
6974
1003
6865
2.23
50.95
13.2
6.4
58.35
57.12
%
2.41
970
6566
993
6787
2.21
50.37
13.9
6.6
0.66
0.67
%
0.34
953
6358
1010
6986
2.20
49.21
13.7
6.6
26.40
28.06
%
4.75
977
6639
81
130
6.51
48.66
3.0
2.8
1230.50
1287.24
e6/l
0.16
74
115
265
1031
2.88
48.34
1.8
1.3
352.49
210.91
u/ml
1.02
248
953
178
550
3.52
47.91
2.6
1.9
1.54
1.79
ug/l
0.15
161
489
936
6340
2.14
47.38
11.3
6.7
1.21
1.21
mmol/l
2.39
873
5869
1008
7070
2.14
45.97
13.0
7.3
1.21
1.21
mmol/l
0.99
875
6133
411
2047
2.35
44.69
1.7
1.4
614.04
506.70
titre
0.57
114
430
905
6150
2.08
44.18
14.4
14.4
1.19
1.24
inr
2.60
764
5105
152
446
3.66
44.16
3.1
1.7
0.23
0.24
g/l
0.42
142
427
154
462
3.58
43.26
3.0
1.6
1.14
1.20
g/l
1.32
147
438
97
216
4.72
40.80
3.2
3.4
2.03
1.44
%
0.56
87
196
281
1224
2.57
40.63
7.3
4.3
0.65
0.65
%
0.00
159
356
292
1296
2.53
40.59
7.6
4.5
0.91
0.97
%
0.18
168
389
176
608
3.13
39.32
3.6
1.9
17.40
6.72
iu/ml
1.47
49
134
155
500
3.32
38.78
1.4
1.2
—
—
—
0
0
276
1228
2.51
37.99
4.3
2.8
70.46
69.79
e9/l
0.11
220
902
888
6223
1.96
37.14
9.0
5.2
34.64
35.91
g/l
8.23
838
5850
342
1702
2.28
36.44
2.1
1.7
—
—
—
0
0
1305
10555
2.26
35.73
16.6
8.1
81.50
79.02
u/l
0.92
1268
10036
273
1247
2.43
35.32
11.5
7.6
9.63
9.48
mmol/l
0.14
260
1200
271
1245
2.42
34.57
8.0
4.8
0.72
0.13
%
0.50
145
296
673
4372
1.93
34.54
3.9
2.6
58.63
78.85
u/l
0.56
634
4069
270
1240
2.42
34.46
7.9
4.5
0.08
0.11
%
0.56
146
332
432
2413
2.08
34.09
3.2
2.5
12.19
13.16
umol/l
2.34
412
2248
352
1823
2.19
33.76
4.6
3.1
4.97
5.05
e9/l
0.05
297
1594
407
2243
2.09
33.17
3.2
2.5
2.30
2.32
g/l
0.34
382
2078
419
2340
2.07
32.92
6.5
3.7
0.80
0.82
mmol/l
2.23
405
2217
58
99
6.04
32.73
3.5
3.1
237.59
212.76
e6/l
0.23
51
86
319
1610
2.22
32.51
3.9
2.9
1.81
1.80
%
0.08
289
1443
221
963
2.50
31.47
6.3
4.2
5.09
5.17
kpa
0.75
210
930
376
2055
2.08
31.09
3.3
2.6
21.31
22.62
%
1.11
355
1921
217
943
2.50
31.06
6.2
4.3
7.42
7.41
ph
0.64
185
789
373
2041
2.08
30.70
2.8
2.0
—
—
—
0
0
66
135
5.06
30.66
3.6
3.0
60.20
56.17
%
0.69
56
121
291
1448
2.23
30.55
3.2
2.1
331.34
382.23
nmol/l
4.21
271
1351
513
3147
1.93
30.43
2.3
1.5
2.34
2.32
g/l
0.07
375
1938
248
1156
2.35
30.37
5.3
3.0
65.41
66.67
g/l
1.57
229
1069
352
1904
2.09
29.78
9.6
6.0
1.08
1.05
mmol/l
1.00
329
1768
1174
9369
1.94
29.74
6.6
4.8
34.78
1984.18
e6/l
—
9
128
736
5117
1.81
28.93
5.1
3.7
49.04
53.82
ng/l
0.11
554
3497
68
153
4.60
28.21
4.1
4.0
—
—
—
0
0
38
48
8.08
28.20
2.2
1.8
35.97
30.77
%
0.94
38
48
271
1359
2.20
27.71
3.4
2.4
0.21
0.21
g/l
0.76
246
1259
993
7635
1.79
26.93
5.5
4.0
0.00
3.94
estimate
1.33
232
1629
33
8
42.02
26.83
1.1
1.0
0.03
0.03
u/ml
—
33
8
52
98
5.45
26.46
3.4
3.0
634.81
599.17
e6/l
0.11
43
81
600
4005
1.80
26.38
4.0
3.2
1506.81
1205.99
ng/l
0.81
518
3416
1045
8187
1.79
26.24
8.2
5.1
6.66
6.62
mmol/l
0.29
1020
7719
1191
9709
1.88
26.21
7.1
4.7
—
3.57
—
0
16
328
1807
2.02
26.05
2.0
1.6
—
—
—
0
0
980
7557
1.76
25.77
5.5
3.9
0.00
0.00
estimate
0.80
231
1596
621
4220
1.77
25.46
2.9
2.2
147.83
226.81
u/l
2.21
593
4007
76
202
3.90
25.35
1.9
1.6
—
—
—
0
0
76
202
3.90
25.35
1.9
1.6
—
—
—
0
0
76
202
3.90
25.35
1.9
1.6
—
—
—
0
0
76
202
3.90
25.35
1.9
1.6
—
—
—
0
0
991
7687
1.76
25.31
5.6
4.0
0.01
0.20
estimate
0.48
223
1540
203
937
2.34
25.21
4.3
2.7
—
—
—
0
0
506
3286
1.79
23.92
9.1
4.7
—
—
—
0
0
312
1745
1.98
23.52
2.0
1.5
—
—
—
0
0
528
3489
1.76
23.41
4.2
2.8
338.79
335.49
umol/l
0.29
476
3089
148
613
2.56
23.24
2.1
1.9
1.61
1.49
g/l
0.71
129
543
94
305
3.21
23.17
2.4
1.7
—
—
—
0
0
33
45
7.47
22.95
1.2
1.4
—
—
—
0
0
234
1191
2.13
22.78
1.6
1.4
—
—
—
0
0
613
4255
1.71
22.62
6.7
4.2
7.40
7.40
ph
0.81
465
3055
140
572
2.59
22.60
1.4
1.2
1.60
0.98
u/ml
0.17
14
35
1231
10317
1.83
22.55
8.5
4.4
15.40
11.82
mm/h
10.96
1169
9647
816
6118
1.68
22.48
4.7
3.5
6.22
6.25
ph
0.28
433
3397
360
2143
1.88
22.39
2.6
2.2
29.42
29.42
s
0.01
348
2081
139
570
2.57
22.26
1.5
1.3
—
—
—
0
0
95
318
3.11
22.23
1.8
1.5
—
—
—
0
0
490
3208
1.76
22.22
2.1
1.9
1.26
1.21
mg/l
0.15
401
2465
603
4188
1.70
22.07
5.9
4.0
0.00
0.01
estimate
1.54
212
1502
569
3897
1.71
21.88
3.1
2.3
2.99
2.78
mg/l
1.45
495
3358
414
2601
1.80
21.51
2.0
1.7
—
—
—
0
0
648
4651
1.66
20.54
3.5
2.4
—
—
—
0
0
80
255
3.25
20.31
3.9
3.6
4.42
4.16
e9/l
0.37
80
255
853
6597
1.62
19.80
3.2
2.5
75.27
76.69
nmol/l
0.81
792
5995
109
422
2.70
19.57
1.5
1.2
16.29
2.42
u/ml
0.60
19
40
91
322
2.94
19.33
1.8
1.4
—
13.91
—
0
5
109
426
2.67
19.21
1.5
1.2
24.28
7.38
u/ml
0.93
27
62
41
84
4.98
19.03
2.7
2.7
34.86
43.02
%
1.38
21
45
129
551
2.46
18.93
7.7
4.7
24.72
24.83
mmol/l
0.15
121
521
114
460
2.59
18.85
6.0
4.0
53.19
60.93
mg/l
0.19
95
397
114
461
2.59
18.77
6.0
4.0
41.11
81.48
mg/l
0.80
95
399
92
333
2.87
18.76
4.0
3.4
60.02
58.29
%
0.49
92
333
112
451
2.59
18.60
1.5
1.2
41.33
33.01
u/ml
0.11
12
20
479
3249
1.68
18.46
4.0
2.7
5.95
6.56
e6/l
0.46
452
2970
569
4034
1.64
18.43
4.6
3.3
0.47
0.42
e6/l
0.19
454
2971
71
224
3.27
18.34
2.0
1.7
—
—
—
0
0
510
3533
1.65
18.03
3.4
2.4
—
—
—
0
0
84
296
2.94
17.98
1.9
1.5
164.23
151.92
au/ml
0.37
26
90
456
3083
1.67
17.66
2.2
2.0
—
—
—
0
0
272
1588
1.86
17.60
10.5
8.1
7.42
7.41
ph
1.16
168
881
851
6690
1.58
17.59
3.8
2.8
—
—
estimate
—
0
0
270
1576
1.86
17.48
10.2
8.0
1.14
0.86
mmol/l
0.52
217
1294
145
676
2.26
17.42
7.8
4.5
—
—
—
0
0
620
4539
1.60
17.34
4.4
3.1
—
—
—
0
0
90
336
2.78
17.33
1.7
1.4
332.17
232.90
u/ml
1.47
58
191
713
5406
1.57
17.07
5.6
4.0
61.86
105.05
e6/l
1.25
542
3760
631
4653
1.59
17.03
4.9
3.4
20.57
81.51
e6/l
2.63
519
3562
269
1590
1.83
16.67
10.6
8.0
4.99
5.08
kpa
0.88
255
1531
269
1591
1.83
16.63
10.6
8.0
12.29
12.30
kpa
0.02
254
1532
101
410
2.56
16.50
6.0
3.9
15.14
3.46
ratio
0.61
58
238
536
3831
1.60
16.36
4.5
3.2
0.00
0.00
estimate
—
5
14
52
145
3.67
16.25
1.8
1.6
62.39
55.75
%
0.57
36
98
97
389
2.59
16.24
2.8
2.2
14.14
11.75
mg/l
1.00
89
358
163
826
2.08
15.85
8.1
7.1
24.76
24.40
mmol/l
0.55
155
793
72
250
2.97
15.84
1.6
1.6
0.58
0.76
g/l
0.55
51
195
106
449
2.46
15.83
2.9
3.3
3.77
3.55
g/l
0.66
100
430
244
1421
1.85
15.81
10.7
8.4
95.37
95.64
%
0.28
231
1379
740
5728
1.54
15.73
5.6
3.8
0.03
0.03
estimate
0.19
195
1320
352
2288
1.69
15.56
1.9
1.7
1213.11
1173.44
nmol/l
0.33
271
1720
223
1270
1.88
15.49
7.4
4.0
7.36
7.35
ph
0.19
159
909
887
7181
1.53
15.05
4.2
3.2
161.38
109.94
ug/l
1.92
834
6733
410
2795
1.63
14.99
4.4
2.9
494.10
526.56
mosm/kgh2o
2.45
373
2463
51
150
3.48
14.74
1.5
1.3
6.41
6.92
g/l
0.22
34
111
51
150
3.48
14.74
1.5
1.3
0.42
0.39
g/l
0.17
34
109
51
150
3.48
14.74
1.5
1.3
2.24
2.78
g/l
1.28
33
109
113
510
2.31
14.65
4.3
3.6
1557.35
323.10
mg/l
0.48
60
221
312
1995
1.70
14.57
3.5
2.6
133.40
116.22
ug/g
0.60
248
1579
42
109
3.93
14.54
1.3
1.1
—
—
—
0
0
225
1317
1.82
14.27
11.9
8.7
117.63
120.71
g/l
1.49
220
1289
137
678
2.12
14.16
2.7
2.2
0.57
0.00
estimate
0.48
35
221
52
161
3.30
13.89
1.6
1.3
—
—
—
0
0
108
491
2.29
13.77
2.4
2.2
192.27
416.91
ug/l
1.29
98
464
74
282
2.70
13.74
4.7
3.8
—
—
—
0
0
395
2720
1.60
13.68
1.4
1.3
32.00
28.49
iu/ml
0.23
123
825
1474
13600
2.02
13.62
34.0
15.5
22.21
23.40
mg/l
0.95
1360
11204
66
238
2.85
13.60
1.1
1.1
—
—
—
0
0
40
106
3.84
13.47
1.1
1.0
—
—
—
0
0
225
1345
1.78
13.26
2.5
2.1
0.00
0.02
estimate
0.78
47
280
147
766
2.01
13.22
1.5
1.2
—
—
—
0
0
49
151
3.32
13.19
1.6
1.3
—
—
—
0
0
369
2529
1.60
12.94
1.3
1.3
11.77
10.34
u/ml
0.13
136
971
241
1483
1.74
12.83
6.1
4.5
5.66
5.82
kpa
1.65
235
1435
494
3630
1.52
12.66
1.4
1.3
1.07
1.72
u/ml
1.02
132
975
486
3561
1.52
12.62
6.5
4.2
90.84
90.20
%
0.23
471
3481
200
1171
1.81
12.62
1.6
1.4
—
—
—
0
0
240
1482
1.73
12.60
5.8
4.6
7.38
7.38
ph
0.16
149
846
116
564
2.14
12.55
4.7
2.6
3.48
3.76
g/l
1.37
108
522
116
565
2.14
12.49
4.7
2.6
4.29
4.20
g/l
0.60
108
522
116
565
2.14
12.49
4.7
2.6
7.34
7.40
g/l
0.16
108
522
25
49
5.17
12.23
2.2
3.7
1.84
0.21
e9/l
0.49
12
27
790
6415
1.46
12.10
23.5
11.2
0.00
0.00
e9/l
0.16
680
5238
55
193
2.92
11.93
2.7
2.2
0.99
0.92
%
0.29
46
130
230
1426
1.72
11.87
6.3
4.6
1.63
1.76
mmol/l
0.23
203
1215
638
4993
1.46
11.76
4.9
3.5
2.33
2.36
mmol/l
4.28
590
4559
63
240
2.69
11.73
1.2
1.1
—
—
—
0
0
159
886
1.88
11.73
1.3
1.3
35.25
44.62
au/ml
—
8
69
51
174
2.99
11.63
1.5
1.2
—
—
—
0
0
90
415
2.24
11.12
1.3
1.3
—
786.36
—
0
11
53
190
2.85
11.08
6.0
3.0
—
—
—
0
0
609
4766
1.45
11.04
5.9
3.3
33.72
31.28
u/l
0.58
574
4523
168
972
1.81
10.99
2.5
2.5
23.98
22.87
au/ml
0.05
20
106
45
148
3.10
10.94
2.3
2.1
-0.13
0.60
mmol/l
0.57
40
143
88
408
2.22
10.74
1.4
1.3
83.33
87.95
titre
—
9
44
560
4346
1.44
10.48
12.9
6.4
—
—
—
0
0
84
388
2.23
10.35
7.0
7.3
1.16
1.30
mmol/l
1.32
73
343
250
1639
1.62
10.35
5.0
3.0
7.04
7.53
umol/l
0.15
216
1430
205
1278
1.69
10.32
13.3
9.1
—
—
—
0
0
535
4128
1.44
10.29
1.9
1.7
19.32
20.38
nmol/l
0.87
468
3510
30
79
3.85
10.23
1.5
1.7
—
—
—
0
0
79
359
2.26
10.13
1.3
1.2
—
—
—
0
0
395
2882
1.49
10.11
1.8
1.7
108683070.21
31400597.03
pmol/l
0.78
334
2414
106
542
2.02
10.06
7.2
5.9
0.99
0.88
%
0.91
101
511
22
29
7.68
9.90
2.2
1.6
—
—
—
0
0
49
181
2.76
9.72
3.7
2.8
—
—
—
0
0
451
3402
1.45
9.67
5.3
4.1
1.02
1.47
kg/l
0.50
296
2245
112
595
1.95
9.54
7.1
5.7
1.50
1.55
%
0.30
106
563
1463
13702
1.76
9.51
34.5
18.1
139.33
139.62
mmol/l
4.62
1438
13440
364
2642
1.49
9.48
5.0
3.9
134.56
408.41
ng/l
3.29
261
1991
199
1258
1.66
9.48
6.4
4.0
4.76
4.55
kpa
0.81
193
1215
1464
13722
1.76
9.39
34.8
18.3
3.96
3.96
mmol/l
0.06
1440
13435
40
135
3.01
9.34
1.7
1.3
1.37
1.20
u/ml
0.06
30
71
33
99
3.38
9.33
1.8
1.4
35.05
34.51
%
0.03
25
64
184
1149
1.68
9.18
5.5
4.0
106.72
84.84
ng/l
1.77
160
1017
135
772
1.82
9.17
14.8
10.8
15.61
15.82
%
0.42
128
744
748
6226
1.38
8.91
2.4
2.1
95.25
96.10
pmol/l
0.20
463
3274
59
253
2.38
8.67
5.2
4.0
2.32
2.55
mmol/l
0.31
40
170
43
158
2.77
8.65
2.9
2.6
1.06
1.11
g/24h
0.05
33
93
26
70
3.76
8.63
52.3
35.3
7.93
6.85
ug/l
0.46
26
61
525
4151
1.39
8.43
4.9
3.3
1.46
0.04
estimate
0.54
188
1283
39
142
2.79
8.00
2.9
2.3
—
—
—
0
0
44
171
2.62
7.97
3.2
2.3
33.57
32.43
pg
1.34
44
171
24
65
3.73
7.91
1.2
1.1
1.67
15.13
u/ml
—
6
8
1217
11078
1.41
7.72
5.5
4.5
14.88
14.73
pmol/l
1.34
1117
10224
71
346
2.10
7.71
2.1
1.7
26585.85
11907.29
e6/l
0.77
52
248
35
123
2.89
7.66
1.3
1.2
—
—
—
0
0
71
347
2.09
7.66
1.6
1.2
46.43
47.23
u/ml
—
8
32
1052
9368
1.36
7.53
5.5
3.3
55.80
45.11
u/l
2.51
1003
8854
59
271
2.22
7.44
7.9
8.6
11.13
11.28
mmol/l
0.11
54
248
59
272
2.21
7.38
7.9
8.6
104.67
105.10
mmol/l
0.26
54
249
45
185
2.47
7.29
1.8
1.6
29.28
24.89
ng/l
0.16
45
185
45
185
2.47
7.29
2.8
2.5
19.97
38.22
iu/ml
—
6
18
173
1130
1.60
7.20
3.3
2.4
0.55
0.48
e6/l
0.10
168
1075
43
174
2.51
7.20
1.3
1.3
—
—
—
0
0
51
224
2.32
7.15
1.5
1.3
26.72
23.50
u/l
0.29
46
183
37
140
2.68
7.09
1.2
1.1
—
—
—
0
0
90
494
1.87
7.01
4.8
2.7
10.20
10.37
g/l
0.10
80
448
333
2506
1.41
6.94
3.8
2.9
1.10
1.11
e6/l
0.01
204
1321
17
28
6.12
6.77
1.1
1.3
29.32
1.59
u/ml
0.46
17
28
167
1102
1.58
6.66
7.2
3.6
1.22
1.23
mmol/l
0.60
148
942
165
1086
1.58
6.65
2.4
2.5
5.64
7.23
ug/l
0.74
138
958
50
226
2.25
6.59
1.3
1.2
—
—
—
0
0
19
50
3.83
6.54
1.6
1.3
1.60
5.08
%
—
5
12
80
434
1.89
6.48
1.3
1.4
262.00
286.50
ug/g
0.44
42
250
83
456
1.86
6.46
6.1
6.1
1.52
1.46
mg/l
0.25
77
417
46
203
2.30
6.41
4.9
5.8
380.27
367.63
umol/l
0.22
38
181
32
119
2.72
6.36
1.2
1.2
106.53
108.47
pmol/l
0.09
32
119
96
556
1.77
6.31
2.7
2.7
20.55
21.04
s
0.55
87
504
225
1603
1.47
6.27
5.1
4.7
32.28
32.43
%
0.07
163
1070
577
4800
1.32
6.21
4.0
3.4
7.03
7.55
mmol/l
2.13
485
4088
175
1186
1.53
6.20
7.0
3.7
—
—
—
0
0
85
477
1.83
6.20
1.7
1.5
12.05
9.52
u/l
0.85
71
375
17
43
3.99
6.17
4.9
3.8
—
—
—
0
0
506
4139
1.32
6.12
3.8
3.1
0.00
0.02
—
9
87
223
1594
1.46
6.10
1.5
1.4
—
—
—
0
0
138
891
1.60
6.04
14.3
9.8
0.71
0.64
%
1.07
133
886
61
310
2.01
5.99
1.8
1.8
—
—
—
0
0
1470
14020
1.57
5.98
27.3
13.7
—
—
—
0
0
19
54
3.55
5.89
4.9
2.4
18.67
164.01
ug/l
0.50
19
49
141
929
1.57
5.68
14.1
9.4
1.31
1.30
%
0.05
136
922
142
939
1.56
5.63
3.2
3.6
4.47
4.55
pmol/l
0.33
126
838
523
4339
1.30
5.62
4.1
3.5
47.93
48.19
mg/l
0.01
327
2782
18
51
3.56
5.61
2.4
1.8
—
—
—
0
0
1494
14341
1.60
5.44
38.4
19.9
81.10
75.26
umol/l
4.42
1481
14188
300
2305
1.37
5.43
4.0
3.1
4.07
2.81
e6/l
0.88
160
1117
529
4412
1.30
5.43
5.0
4.2
8.90
8.89
mg/mmol
0.00
327
2750
176
1229
1.49
5.42
1.2
1.2
—
—
—
0
0
16
43
3.75
5.37
1.0
1.0
—
—
—
0
0
21
68
3.12
5.35
1.1
1.2
—
—
—
0
0
72
404
1.82
5.30
11.4
9.9
—
—
—
0
0
150
1020
1.52
5.25
4.2
3.1
162.87
214.67
ng/l
0.94
136
932
47
230
2.07
5.15
1.3
1.2
55.57
27.67
u/l
0.58
42
201
37
167
2.24
4.96
1.7
1.9
—
—
—
0
0
32
136
2.38
4.92
1.4
1.2
—
—
—
0
0
12
20
6.04
4.91
5.5
3.1
—
—
—
0
0
54
284
1.93
4.87
1.4
1.5
68.23
63.11
mmol/l
0.40
40
234
30
125
2.43
4.82
1.6
1.4
137545.32
123600.39
e6/l
0.04
19
79
188
1361
1.43
4.81
3.0
2.4
37.21
41.05
u/l
0.26
159
1141
1480
14233
1.51
4.69
23.2
11.9
26.75
25.30
u/l
2.17
1455
13853
188
1371
1.42
4.62
4.9
4.3
15.31
19.90
ug/l
0.23
151
1104
18
59
3.07
4.52
1.1
1.3
814.29
800.00
titre
—
7
10
20
70
2.88
4.50
2.6
1.8
2.04
1.94
umol/l
0.23
20
62
71
419
1.73
4.45
1.2
1.2
—
—
—
0
0
646
5627
1.25
4.41
2.3
2.1
—
—
—
0
0
97
623
1.59
4.40
2.1
1.6
0.37
0.34
mg/l
0.14
41
280
31
140
2.24
4.19
1.1
1.1
—
—
—
0
0
32
147
2.20
4.16
1.3
1.1
—
—
—
0
0
65
385
1.72
4.05
3.2
3.3
1.97
2.43
index
0.33
35
199
14
42
3.35
4.04
1.0
1.1
5.64
7.93
u/ml
—
8
35
1318
12499
1.30
4.00
7.4
6.2
39.57
38.90
mmol/mol
1.74
1231
11749
15
48
3.15
3.93
1.1
1.1
—
—
—
0
0
248
1944
1.33
3.89
1.3
1.2
—
—
—
0
0
22
88
2.52
3.89
1.1
1.2
—
—
—
0
0
59
345
1.74
3.86
1.6
1.8
3953.08
1195.26
e6/l
0.31
50
272
83
533
1.59
3.81
1.1
1.1
—
—
—
0
0
17
60
2.85
3.79
1.1
1.1
35.00
227.59
ng/l
—
5
17
83
535
1.58
3.75
1.6
1.6
8.99
9.60
u/ml
0.11
24
120
58
341
1.73
3.73
2.6
2.3
124.10
129.43
g/l
0.89
49
275
58
341
1.73
3.73
1.6
1.7
34.89
15.64
e6/l
0.51
47
258
64
387
1.68
3.72
1.0
1.1
3.20
7.61
eliau/ml
—
6
52
25
109
2.31
3.69
2.0
1.4
—
—
—
0
0
13
34
3.85
3.69
1.7
1.4
23.86
29.32
%
—
7
22
1348
12857
1.30
3.67
6.8
5.6
1.87
1.89
mu/l
0.18
1257
11992
23
97
2.39
3.65
3.3
2.5
595.00
597.97
ml
0.01
17
64
11
25
4.42
3.62
1.1
1.2
—
—
—
0
0
11
25
4.42
3.62
1.0
1.1
—
—
—
0
0
16
57
2.83
3.52
1.5
1.3
157.31
161.12
mmol/24h
0.07
16
57
17
64
2.67
3.40
4.2
2.5
—
—
—
0
0
13
42
3.11
3.37
1.2
1.1
—
—
—
0
0
345
2873
1.26
3.37
4.3
2.9
2.45
2.45
mmol/l
0.09
320
2588
9
18
5.02
3.37
6.8
3.1
—
—
—
0
0
27
127
2.15
3.36
1.1
1.2
—
—
—
0
0
45
254
1.79
3.35
2.1
2.0
4.51
4.82
mmol/24h
0.29
38
228
16
59
2.73
3.32
1.0
1.1
199.34
166.22
iu/ml
0.28
16
59
12
33
3.66
3.29
1.7
1.8
—
—
—
0
0
11
28
3.95
3.29
2.1
2.0
—
—
—
0
0
7
11
6.39
3.18
3.3
2.1
3.29
3.56
mg/l
—
7
11
31
158
1.98
3.15
2.2
2.2
—
—
—
0
0
13
44
2.97
3.14
1.0
1.1
2.25
17.38
u/ml
—
6
28
12
35
3.45
3.10
3.8
3.1
—
—
—
0
0
68
441
1.57
3.05
1.9
2.1
4.35
17.03
iu/l
0.49
24
181
34
182
1.89
3.02
2.0
1.5
521.10
344.55
mu/l
0.69
29
147
20
87
2.32
3.01
1.4
1.1
1657.40
1474.87
miu/ml
0.24
20
87
17
69
2.48
2.96
3.9
1.6
—
—
—
0
0
129
963
1.37
2.83
2.3
2.3
11.25
12.47
nmol/l
0.85
117
865
32
173
1.87
2.78
1.7
1.5
274.80
277.54
mosm/kgh2o
0.29
25
127
75
509
1.50
2.76
4.7
3.5
6449.66
1116.64
u/ml
0.44
62
439
30
159
1.90
2.76
1.7
1.3
1282.00
1847.75
e6/l
0.54
25
106
30
159
1.90
2.76
1.6
1.3
0.16
0.29
nmol/l
0.56
24
121
53
333
1.61
2.74
1.1
1.1
6.28
6.14
u/ml
0.02
36
197
7
14
5.02
2.73
1.9
1.0
—
—
—
0
0
6
10
6.02
2.70
1.5
1.0
—
—
—
0
0
43
259
1.68
2.62
1.0
1.1
4.38
4.41
u/ml
0.01
29
129
9
25
3.61
2.57
1.3
1.4
—
—
—
0
0
12
44
2.74
2.55
1.8
1.9
—
—
—
0
0
25
131
1.92
2.41
1.8
1.3
21779.00
90014.60
e6/l
0.69
16
67
79
559
1.43
2.39
1.5
1.3
235.25
244.28
miu/ml
0.07
31
275
9
27
3.35
2.39
2.0
1.0
—
—
—
0
0
9
27
3.35
2.39
2.0
1.0
—
—
—
0
0
9
27
3.35
2.39
2.0
1.0
—
—
—
0
0
26
139
1.88
2.37
3.3
3.3
11.06
13.13
index
0.83
17
86
22
111
2.00
2.36
2.2
1.4
0.72
1.20
promille
0.75
16
90
20
98
2.05
2.32
1.2
1.0
15.50
0.38
u/ml
—
9
30
95
700
1.38
2.30
2.9
2.3
1834.73
6443.70
u/l
2.28
36
302
13
53
2.46
2.28
3.9
1.9
42.72
40.34
g/l
0.95
13
53
6
13
4.63
2.27
4.5
2.0
—
—
—
0
0
17
79
2.16
2.25
2.8
1.9
32.23
30.01
umol/l
0.34
17
73
60
408
1.49
2.24
1.1
1.2
—
—
—
0
0
39
240
1.64
2.23
1.0
1.1
6.08
6.68
u/ml
0.07
23
105
25
135
1.87
2.22
1.7
1.3
—
—
—
0
0
11
41
2.69
2.20
1.3
1.1
—
—
—
0
0
12
48
2.51
2.18
4.2
2.4
0.57
0.62
mmol/l
1.17
12
48
1333
12871
1.21
2.18
5.9
4.9
5.94
5.87
mmol/l
1.00
1221
11840
1296
12484
1.20
2.16
4.7
4.1
1.33
1.26
mmol/l
3.29
1193
11527
37
227
1.64
2.15
1.4
1.2
4.50
5.02
u/ml
0.10
20
94
10
36
2.79
2.14
1.2
1.3
—
—
—
0
0
19
95
2.01
2.11
1.3
1.1
7.31
0.61
u/ml
—
9
39
37
229
1.63
2.09
1.1
1.0
0.14
0.30
u/ml
0.63
21
72
49
325
1.52
2.08
1.1
1.1
1.57
1.50
u/ml
0.02
32
151
43
277
1.57
2.07
1.4
1.1
—
—
—
0
0
45
294
1.55
2.04
3.7
2.5
83.68
124.24
ug/min
0.41
28
182
43
278
1.56
2.04
1.4
1.1
—
—
—
0
0
141
1122
1.28
2.04
1.3
1.2
118.25
133.79
u/ml
0.16
54
428
1511
14819
1.33
1.99
46.7
23.7
255.00
253.75
e9/l
0.29
1491
14538
14
64
2.20
1.94
3.2
2.5
—
—
—
0
0
1511
14824
1.33
1.94
46.3
23.6
91.19
90.84
fl
2.14
1497
14688
55
380
1.46
1.94
1.1
1.1
1.72
2.51
u/ml
0.31
38
211
22
120
1.84
1.93
1.2
1.2
—
—
—
0
0
1511
14826
1.32
1.92
46.4
23.6
4.35
4.47
e12/l
15.29
1490
14506
1511
14826
1.32
1.92
47.4
24.1
39.44
40.41
%
2.54
1497
14679
1511
14826
1.32
1.92
46.2
23.5
30.22
30.23
pg
0.12
1498
14688
47
315
1.51
1.92
1.0
1.1
4.28
1.80
u/ml
0.41
33
168
1511
14829
1.32
1.89
46.6
23.7
7.06
6.74
e9/l
2.59
1488
14499
22
121
1.83
1.88
1.0
1.1
267.71
246.33
mg/l
0.16
17
105
7
22
3.19
1.88
1.1
1.1
—
—
—
0
0
9
34
2.66
1.86
1.6
3.2
17.78
5.88
ug/l
—
9
34
1511
14832
1.32
1.86
46.8
23.8
130.62
134.24
g/l
17.55
1499
14691
36
229
1.59
1.85
1.2
1.2
—
—
—
0
0
41
269
1.54
1.85
1.1
1.1
14.17
17.76
au/ml
—
8
68
27
160
1.70
1.82
1.7
1.3
—
—
nmol/l
—
0
0
25
146
1.72
1.78
1.5
2.3
—
—
—
0
0
90
689
1.32
1.76
2.5
2.3
—
—
—
0
0
468
4245
1.14
1.68
1.6
1.5
—
—
—
0
0
8
31
2.59
1.66
2.4
1.1
—
—
—
0
0
1200
11564
1.15
1.65
35.8
19.3
13.91
13.56
%
15.00
1192
11415
36
237
1.53
1.63
1.3
1.1
69.36
86.55
iu/ml
0.12
11
51
101
1270
0.78
1.63
1.4
1.3
—
—
—
0
0
5
14
3.58
1.61
1.6
1.1
—
—
—
0
0
12
56
2.15
1.61
3.6
2.7
—
—
—
0
0
23
136
1.70
1.59
1.7
1.4
—
—
—
0
0
10
44
2.28
1.55
1.1
1.1
—
—
—
0
0
10
44
2.28
1.55
1.1
1.1
—
—
—
0
0
10
44
2.28
1.55
1.1
1.1
—
—
—
0
0
5
15
3.34
1.52
1.6
1.2
—
—
—
0
0
29
185
1.58
1.52
1.3
1.2
—
—
—
0
0
7
27
2.60
1.51
2.4
2.0
—
—
—
0
0
7
27
2.60
1.51
1.6
1.4
—
—
—
0
0
6
21
2.86
1.50
3.5
1.7
—
—
—
0
0
14
72
1.95
1.49
1.5
3.0
14.86
16.76
%
0.75
14
72
13
65
2.01
1.48
1.3
1.2
16.08
9.26
mm/h
0.77
13
65
203
1744
1.19
1.48
1.6
1.5
—
—
—
0
0
22
132
1.68
1.46
2.0
1.6
—
—
—
0
0
5
16
3.13
1.44
2.2
1.3
63.80
46.69
umol/l
—
5
16
20
118
1.70
1.41
1.0
1.1
15.20
15.49
u/ml
—
6
49
63
476
1.34
1.40
2.0
2.7
—
—
—
0
0
353
3180
1.14
1.39
5.7
5.6
2.42
3.01
ug/l
0.56
313
2840
45
325
1.40
1.33
6.2
4.5
—
—
—
0
0
5
18
2.78
1.28
3.2
5.9
—
—
—
0
0
94
1154
0.80
1.28
1.4
1.7
3.37
3.46
mmol/l
0.31
55
798
86
689
1.26
1.26
5.3
3.5
1.02
1.02
ratio
0.22
79
638
20
123
1.63
1.24
1.1
1.1
11.78
7.58
iu/ml
—
9
33
207
1811
1.16
1.24
2.0
1.8
—
—
—
0
0
8
37
2.17
1.21
1.5
1.4
2.04
3.50
mmol/l
—
8
32
12
64
1.88
1.18
1.7
1.6
—
—
—
0
0
33
231
1.44
1.18
1.2
1.2
—
—
—
0
0
0
34
0.00
1.16
0.0
1.1
—
—
—
0
0
84
680
1.25
1.15
1.9
2.0
—
—
—
0
0
5
20
2.50
1.15
1.6
2.0
—
—
—
0
0
5
20
2.50
1.15
1.0
1.1
—
42.63
—
0
8
5
20
2.50
1.15
1.0
1.0
3.26
8.39
u/ml
—
5
20
17
103
1.66
1.13
1.2
1.2
0.68
0.54
ratio
—
8
60
10
51
1.97
1.11
1.2
1.1
—
—
—
0
0
10
182
0.55
1.10
1.1
1.4
6.75
7.52
mmol/l
—
10
159
7
31
2.26
1.10
1.7
2.8
33.43
45.74
%
—
7
31
7
31
2.26
1.10
3.4
5.6
10.14
7.65
%
—
7
31
7
32
2.19
1.08
6.6
6.7
7.81
5.26
kpa
—
7
32
7
32
2.19
1.08
1.7
1.1
38.91
56.49
%
—
7
27
36
261
1.39
1.08
3.4
3.5
0.84
0.81
nmol/l
0.16
25
219
1347
13187
1.13
1.08
5.5
4.9
4.54
4.63
mmol/l
2.66
1253
12356
18
113
1.60
1.06
1.2
1.2
—
—
—
0
0
10
53
1.89
1.01
1.2
1.0
16.81
15.26
u/ml
—
5
41
27
379
0.71
1.00
1.4
1.5
1.23
1.27
mm
0.16
17
276
28
389
0.71
0.98
1.4
1.5
—
—
—
0
0
0
29
0.00
0.97
0.0
1.4
—
61.59
—
0
29
21
140
1.51
0.97
1.5
1.3
6.61
6.44
mmol/l
0.10
21
130
62
496
1.26
0.97
1.8
1.9
—
—
—
0
0
99
834
1.20
0.96
1.6
1.5
28.50
25.46
iu/l
0.41
90
715
29
396
0.73
0.93
1.4
1.6
—
—
—
0
0
1361
13362
1.12
0.92
6.1
5.6
2.66
2.70
mmol/l
0.94
1264
12464
75
896
0.83
0.85
1.6
1.6
1114.45
993.13
mu/l
0.54
60
763
22
154
1.43
0.83
3.2
2.3
—
—
—
0
0
62
507
1.23
0.83
2.9
2.4
—
—
—
0
0
38
486
0.78
0.80
1.1
1.1
0.84
0.64
ratio
—
5
58
204
1850
1.12
0.77
1.3
1.3
—
—
—
0
0
1334
13113
1.10
0.76
5.4
4.8
1.42
1.48
mmol/l
5.73
1235
12203
38
298
1.28
0.74
3.0
1.9
1.17
0.84
nmol/l
1.27
25
252
10
159
0.63
0.72
1.4
1.6
—
—
—
0
0
39
310
1.26
0.69
2.5
2.3
—
—
—
0
0
135
1509
0.88
0.68
1.6
1.9
3.31
3.42
ratio
0.49
94
1145
113
999
1.14
0.66
1.2
1.3
—
—
—
0
0
7
44
1.59
0.65
1.4
1.7
48.86
80.73
nmol/24h
—
7
44
127
1135
1.13
0.64
2.6
2.5
6.06
6.14
ph
0.37
80
763
43
520
0.82
0.60
1.0
1.1
1.52
1.56
g/l
0.55
43
520
0
21
0.00
0.60
0.0
1.2
—
1.77
—
0
21
42
509
0.82
0.60
1.5
1.5
63.73
61.21
ug/l
0.12
33
435
22
166
1.33
0.58
2.3
2.3
—
—
—
0
0
6
37
1.62
0.55
2.3
1.6
7.23
8.12
mmol/l
—
6
37
28
221
1.27
0.55
1.0
1.1
1.48
2.42
eliau/ml
—
10
93
83
730
1.14
0.55
2.4
1.9
—
—
—
0
0
78
683
1.15
0.55
2.5
1.9
—
—
—
0
0
6
39
1.54
0.53
1.0
1.1
15.37
46.50
iu/ml
—
6
39
83
735
1.14
0.51
2.4
1.9
—
—
—
0
0
9
65
1.39
0.50
1.2
1.2
158.43
167.69
pmol/l
—
9
65
14
101
1.39
0.49
1.0
1.0
—
—
—
0
0
203
1893
1.08
0.48
3.4
3.3
0.74
0.78
ug/l
0.21
144
1244
12
86
1.40
0.44
1.0
1.2
—
—
—
0
0
81
727
1.12
0.42
2.4
1.9
—
—
—
0
0
17
131
1.30
0.42
2.9
2.7
—
—
—
0
0
5
33
1.52
0.41
1.4
1.1
237.20
293.83
pmol/l
—
5
23
0
15
0.00
0.41
0.0
4.8
—
0.21
—
0
15
83
748
1.12
0.41
1.8
1.7
—
—
—
0
0
11
79
1.40
0.40
1.4
2.7
7.75
8.22
mmol/l
0.24
11
79
20
159
1.26
0.40
1.3
1.1
—
—
—
0
0
65
579
1.13
0.39
2.4
1.9
—
—
—
0
0
80
724
1.11
0.38
2.4
1.8
—
—
—
0
0
16
201
0.79
0.35
1.1
1.2
—
—
—
0
0
29
246
1.18
0.34
2.0
2.4
9.31
6.16
umol/l
0.25
16
181
43
378
1.14
0.33
1.4
1.3
—
—
—
0
0
11
83
1.33
0.32
2.4
2.0
120.64
107.25
ng/l
0.26
11
83
509
5223
0.96
0.29
3.4
3.0
—
—
—
0
0
8
64
1.25
0.27
1.9
2.1
—
—
—
0
0
61
666
0.91
0.26
1.1
1.1
—
—
—
0
0
18
150
1.20
0.26
7.1
4.8
10.70
54.21
u/ml
—
5
50
49
539
0.91
0.25
1.5
1.2
0.92
0.89
g/l
0.33
49
539
169
1614
1.05
0.24
1.6
1.7
—
—
—
0
0
24
275
0.87
0.23
3.9
3.5
21.58
26.01
mg/l
0.46
18
192
31
348
0.89
0.23
1.1
1.1
—
—
—
0
0
5
39
1.28
0.23
1.0
1.2
26.60
27.64
s
—
5
39
5
42
1.19
0.21
2.4
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
6.98
—
0
6
9
79
1.14
0.15
1.4
1.3
117.44
140.17
nmol/l
—
9
79
1147
11544
0.98
0.14
36.2
20.2
330.96
332.15
g/l
4.24
1136
11477
11
126
0.87
0.11
1.0
1.1
—
—
—
0
0
5
45
1.11
0.09
1.4
1.8
—
—
—
0
0
6
55
1.09
0.09
3.7
1.3
—
—
—
0
0
24
254
0.94
0.06
1.5
1.9
—
—
—
0
0
572
5690
1.01
0.04
2.1
1.9
1.43
1.34
mmol/l
1.45
475
4839
37
383
0.97
0.04
1.4
1.3
—
—
—
0
0
29
283
1.03
0.01
1.5
1.5
0.21
0.34
nmol/l
1.63
21
223
0
6
0.00
-0.00
0.0
2.0
—
44.00
—
0
6
5
51
0.98
-0.00
1.2
1.7
0.00
0.00
estimate
—
5
51
0
8
0.00
-0.00
0.0
1.4
—
0.15
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
299.40
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
-0.00
2.2
2.2
165.60
154.98
nmol/l
—
5
50
0
5
0.00
-0.00
0.0
1.0
—
1766.60
—
0
5
9
92
0.98
-0.00
1.3
1.4
81.67
78.63
umol/l
—
9
92
0
8
0.00
-0.00
0.0
2.3
—
0.65
—
0
8
0
7
0.00
-0.00
0.0
4.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint GENERALI_SKIN_ERUPT_DRUGS_MEDICAM and mortality.

Females

Parameter HR [95% CI] p-value
GENERALI_SKIN_ERUPT_DRUGS_MEDICAM 1.819 [1.6, 2.07] < 0.001
Birth year 0.996 [0.99, 1.0] 0.29

During the follow-up period (1.1.1998 — 31.12.2019), 1245 out of 5640 females with GENERALI_SKIN_ERUPT_DRUGS_MEDICAM died.

Males

Parameter HR [95% CI] p-value
GENERALI_SKIN_ERUPT_DRUGS_MEDICAM 2.073 [1.77, 2.43] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 840 out of 3833 males with GENERALI_SKIN_ERUPT_DRUGS_MEDICAM died.

Mortality risk

Mortality risk for people of age

years, who have GENERALI_SKIN_ERUPT_DRUGS_MEDICAM.

N-year risk Females Males
1 0.171% 0.399%
5 0.945% 2.288%
10 2.696% 5.745%
15 5.097% 10.828%
20 8.893% 17.877%

Relationships between endpoints

Index endpoint: GENERALI_SKIN_ERUPT_DRUGS_MEDICAM – Generalized skin eruption due to drugs and medicaments

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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