testicular disease: A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly males |
244368 |
2. Check conditionsNone |
244368 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
1666 |
4. Check minimum number of eventsNone |
1666 |
5. Include endpointsNone |
1666 |
6. Filter based on genotype QC (FinnGen only) |
1412 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E29
- Name in latin
- Hypofunctio testium
Similar endpoints
↥List of similar endpoints to
Testicular hypofunction
based on the number of shared cases.
Similar with more cases:
- Testicular dysfunction
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4793 | - | 4793 |
| Only index persons | 4698 | - | 4698 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.13 | - | 0.13 |
| Only index persons | 0.18 | - | 0.18 |
| Median age at first event (years) | |||
| Whole population | - | - | 48.75 |
| Only index persons | - | - | 48.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1412 | - | 1412 |
| Unadjusted period prevalence (%) | 0.65 | - | 0.65 |
| Median age at first event (years) | 52.75 | - | 52.75 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1494
- Matched controls
- 14940
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
256.9
307.7
1370
616
E29.1
ICD-10 Finland
Testicular hypofunction
936.8
307.7
1325
124
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
47.3
307.7
272
70
121
Kela drug reimbursment
Severe hypofunction of sexual glands
378.6
307.7
503
20
Y28
ICPC
Limited function/disability (Y)
44.1
251.6
151
38
A55
ICPC
General and Unspecified, Local injection/infiltration
21.4
236.3
182
96
A50
ICPC
General and Unspecified, Medication/prescr/renewal
11.2
207.9
236
246
WVA30, ,
SPAT
8.0
195.4
298
450
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
41.4
117.1
71
18
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
8.7
101.6
134
167
T99
ICPC
Endocr/metab/nutrit disease other
13.5
92.0
88
69
G47.3
ICD-10 Finland
Sleep apnoea
2.9
86.2
671
3280
E29.9
ICD-10 Finland
Testicular dysfunction, unspecified
21.5
71.9
54
26
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
67.2
64
*
T55
ICPC
Metabolic, Local injection/infiltration
29.5
64.3
43
15
G03GA01
ATC
chorionic gonadotrophin; parenteral
80.9
55.4
62
8
R5140
NOMESCO Finland
Monitoring the use of the aid
2.9
55.4
316
1267
KFC00
NOMESCO Finland
Unilateral orchiectomy
9.5
55.1
66
72
N48.4
ICD-10 Finland
Impotence of organic origin
4.3
54.6
150
376
L02BG04
ATC
letrozole; oral
18.2
48.2
39
22
T28
ICPC
Limited function/disability (T)
11.2
47.0
50
46
S55
ICPC
Skin, Local injection/infiltration
17.7
46.4
38
22
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
4.2
44.2
126
324
N06AX11
ATC
mirtazapine; oral
2.2
41.9
553
3197
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
41.0
293
1301
G04CA01
ATC
alfuzosin; oral
2.4
39.8
355
1741
WX723
NOMESCO Finland
CPAP therapy
3.4
39.0
153
489
R53
ICD-10 Finland
Malaise and fatigue
2.3
38.3
378
1933
H03AA01
ATC
levothyroxine sodium; systemic
2.8
37.2
209
820
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.0
36.8
582
3560
N05BA04
ATC
oxazepam; oral
2.2
36.8
374
1932
N06AB10
ATC
escitalopram; oral
2.3
36.7
353
1782
N05CF02
ATC
zolpidem; oral
2.4
36.2
294
1378
N02AX02
ATC
tramadol; systemic, rectal
2.0
35.7
706
4657
D75.1
ICD-10 Finland
Secondary polycythaemia
8.6
35.7
46
55
N06AX16
ATC
venlafaxine; oral
2.5
35.4
252
1111
A02BC05
ATC
esomeprazole; systemic
2.0
34.7
603
3795
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
7.5
34.5
50
69
N03AX12
ATC
[U] gabapentin; oral
2.4
33.5
265
1225
J01FA10
ATC
azithromycin; systemic
1.9
32.9
856
6133
WX780
NOMESCO Finland
Remote monitoring CPAP
3.0
32.8
152
535
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
32.8
749
5138
N03AX16
ATC
[U] pregabalin
2.2
32.7
352
1851
N06AX21
ATC
duloxetine; oral
2.7
32.6
199
812
N06AX26
ATC
vortioxetine; oral
2.8
32.0
172
657
N62
ICD-10 Finland
Hypertrophy of breast
6.3
31.9
54
88
M01AH05
ATC
etoricoxib; oral
2.0
31.9
1026
7853
N05CF01
ATC
zopiclone; oral
2.0
31.8
447
2595
N06AX12
ATC
bupropion; oral
2.7
31.4
181
717
J01MA02
ATC
ciprofloxacin; systemic
1.9
31.2
586
3754
H02AB09
ATC
hydrocortisone; systemic
7.0
30.7
47
69
R03AC02
ATC
salbutamol; inhalant
1.9
29.6
776
5500
J01AA02
ATC
doxycycline; systemic
2.0
29.5
1118
8917
R01AD09
ATC
mometasone; nasal
1.9
29.3
668
4530
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
29.1
718
4986
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
10.9
28.7
31
29
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.8
27.7
149
569
N46
ICD-10 Finland
Male infertility
3.8
26.9
84
230
N04BC05
ATC
pramipexole; oral
3.2
26.8
114
381
S50
ICPC
Skin, Medication/prescr/renewal
10.2
26.5
30
30
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
26.4
391
2288
E66.00
ICD-10 Finland
Metabolic syndrome
2.9
25.8
129
473
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
25.6
307
1666
N05AH04
ATC
quetiapine; oral
2.0
25.5
327
1817
E66.01
ICD-10 Finland
Obesity due to excess calories
2.6
25.5
159
654
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
25.4
696
4922
-50
ICPC
Medication/prescr/renewal
4.1
25.3
71
180
R06.0
ICD-10 Finland
Dyspnoea
2.0
25.3
365
2114
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
25.2
354
2031
T50
ICPC
Metabolic, Medication/prescr/renewal
30.6
25.1
33
11
M03BX02
ATC
tizanidine; oral
1.8
24.9
973
7606
R01AD12
ATC
fluticasone furoate; nasal
1.8
24.6
472
2994
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.9
24.5
441
2743
L02BG03
ATC
anastrozole; oral
68.6
23.9
27
*
N06AB04
ATC
citalopram; systemic
2.1
23.8
281
1512
J01DB01
ATC
cefalexin; oral
2.1
23.7
1248
10622
Q98.0
ICD-10 Finland
Klinefelter syndrome karyotype 47,XXY
42.2
23.7
29
7
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.6
23.5
152
635
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.1
23.1
103
354
R01AD58
ATC
fluticasone, combinations; nasal
1.9
23.0
396
2420
A02BC03
ATC
lansoprazole; oral
1.9
22.8
365
2179
A02BC02
ATC
pantoprazole; systemic
1.7
22.8
953
7501
XKD00
NOMESCO Finland
Uroflowmetry
2.0
22.7
285
1567
M54.5
ICD-10 Finland
Low back pain
1.7
21.9
557
3812
ZXE00
NOMESCO Finland
One hour or less
1.8
21.8
489
3227
P06
ICPC
Sleep disturbance
2.1
21.8
231
1191
N06AX22
ATC
agomelatine; oral
4.3
21.8
57
137
N02BF01
ATC
gabapentin; oral
2.4
21.7
167
756
F51.0
ICD-10 Finland
Nonorganic insomnia
2.0
21.2
273
1511
Q98.4
ICD-10 Finland
Klinefelter syndrome, unspecified
50.8
21.2
25
5
T29
ICPC
Endocr/metab/nutr sympt/compl other
5.1
21.0
44
88
Y50
ICPC
Male Genital, Medication/prescr/renewal
28.5
21.0
28
10
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
20.9
218
1116
N40
ICD-10 Finland
Hyperplasia of prostate
1.8
20.9
412
2615
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
20.8
306
1771
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
20.7
469
3096
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
16.0
20.6
33
21
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
20.5
434
2810
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
20.4
818
6278
R06AX27
ATC
desloratadine; oral
1.8
20.4
406
2581
Z71.8
ICD-10 Finland
Other specified counselling
1.7
19.9
465
3089
Y05
ICPC
Scrotum/testis sympt/compl other
4.3
19.9
52
125
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
+∞
19.8
19
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
19.7
512
3501
N05BA12
ATC
alprazolam; oral
2.3
19.6
153
695
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.3
19.6
77
245
C07AA05
ATC
propranolol; systemic
1.9
19.6
272
1542
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
19.6
370
2312
M48.0
ICD-10 Finland
Spinal stenosis
2.3
19.4
152
692
M01AB05
ATC
diclofenac; systemic, rectal
1.7
19.3
1013
8282
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
19.2
350
2160
M03BC51
ATC
orphenadrine, combinations; systemic
1.8
19.2
390
2488
A02BC01
ATC
omeprazole; systemic
1.8
19.1
318
1910
M79.6
ICD-10 Finland
Pain in limb
1.7
19.1
594
4251
UKC02
NOMESCO Finland
Cystoscopy
2.0
19.0
231
1249
M54.4
ICD-10 Finland
Lumbago with sciatica
1.9
19.0
280
1617
J02AC01
ATC
fluconazole; systemic
1.9
19.0
286
1664
N02BE01
ATC
paracetamol; systemic, rectal
1.9
18.9
1268
11089
R01AD08
ATC
fluticasone; nasal
1.7
18.8
413
2692
E22.1
ICD-10 Finland
Hyperprolactinaemia
101.3
18.6
20
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
18.5
444
2963
J01CA04
ATC
amoxicillin; systemic
1.8
18.5
1185
10167
J01MA12
ATC
levofloxacin; systemic
1.9
18.4
261
1487
SPAT1262
SPAT
Handing over of treatment supplies
1.9
18.2
249
1402
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
18.1
203
1065
E0000UV, ,
ATC
1.7
18.1
527
3695
H02AB04
ATC
methylprednisolone; systemic
2.1
17.9
184
934
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.0
17.8
226
1240
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
17.7
17
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.9
17.7
247
1399
H02AB06
ATC
prednisolone; systemic
1.6
17.7
636
4694
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.8
17.6
91
339
N06BA04
ATC
methylphenidate; oral
3.1
17.4
76
258
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
17.4
773
5993
R03DC03
ATC
montelukast; oral
2.0
17.3
214
1162
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
17.2
186
962
N06AB06
ATC
sertraline; oral
2.1
17.1
173
873
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
17.1
231
1293
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
17.1
349
2219
N06AB03
ATC
fluoxetine; oral
2.2
16.9
159
780
J05AB11
ATC
valaciclovir; oral
2.1
16.9
182
941
M01AE02
ATC
naproxen; oral, rectal
1.6
16.9
770
5991
J01FA06
ATC
roxithromycin; oral
1.6
16.8
500
3509
R02
ICPC
Shortness of breath/dyspnoea
2.1
16.7
161
797
ZX114, ,
SPAT
5.9
16.7
30
52
E29.8
ICD-10 Finland
Other testicular dysfunction
27.9
16.5
22
8
L03
ICPC
Low back symptom/complaint
1.7
16.4
384
2530
Y08
ICPC
Sexual function sympt/compl male
6.2
16.4
28
46
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
16.4
121
536
R06.5
ICD-10 Finland
Mouth breathing
2.0
16.4
208
1139
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.0
16.3
75
262
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
16.3
404
2702
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
16.2
340
2174
N02BF02
ATC
pregabalin; oral
2.4
16.2
111
476
WVA20, ,
SPAT
3.2
16.1
66
216
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.2
16.0
64
206
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
16.0
300
1857
DHB50
NOMESCO Finland
Turbinoplasty
3.0
15.8
71
245
H04.10
ICD-10 Finland
Dry eye syndrome
2.2
15.8
139
664
E89.5
ICD-10 Finland
Postprocedural testicular hypofunction
60.7
15.8
18
*
L02BA01
ATC
tamoxifen; oral
15.9
15.7
25
16
R06AE07
ATC
cetirizine; oral
1.6
15.6
552
4024
R50.9
ICD-10 Finland
Fever, unspecified
1.9
15.6
234
1353
N05CD07
ATC
temazepam; oral
2.2
15.5
131
615
L28
ICPC
Limited function/disability (L)
2.0
15.2
180
961
Y29
ICPC
Genital symptom/complaint male other
4.6
15.2
36
80
R06AX22
ATC
ebastine; oral
1.9
15.2
219
1250
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
15.2
317
2021
J05AB01
ATC
aciclovir; systemic
1.8
15.2
243
1434
R01BA52
ATC
pseudoephedrine, combinations; oral
1.7
15.1
365
2418
E66.8
ICD-10 Finland
Other obesity
2.7
15.1
84
326
N06AB05
ATC
paroxetine; oral
2.5
15.0
100
423
R03BA08
ATC
ciclesonide; inhalant
2.3
15.0
115
518
C03CA01
ATC
furosemide; systemic
1.8
15.0
265
1610
J01AA04
ATC
lymecycline; systemic
2.0
14.9
184
997
SPAT1254
SPAT
Administration of medicine
2.0
14.8
164
855
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
14.8
363
2415
R51.80
ICD-10 Finland
Headache
1.9
14.7
200
1119
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
14.7
134
649
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
14.6
153
781
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
14.6
122
570
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
14.6
767
6084
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
151.4
14.5
15
*
J34.3
ICD-10 Finland
Hypertrophy of nasal turbinates
3.1
14.4
59
193
J01EA01
ATC
trimethoprim; systemic
2.2
14.3
124
589
M25.5
ICD-10 Finland
Pain in joint
1.6
14.2
453
3209
R03BA05
ATC
fluticasone; inhalant
1.8
14.1
220
1285
C09CA06
ATC
candesartan; oral
1.7
14.1
334
2197
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
14.1
241
1449
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
2.0
14.0
169
908
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
13.9
104
463
C07AB07
ATC
bisoprolol; oral
1.5
13.7
577
4346
Z01.2
ICD-10 Finland
Dental examination
1.5
13.6
637
4904
E30.09
ICD-10 Finland
Delayed puberty NOS
+∞
13.6
13
*
H01AC01
ATC
somatropin; parenteral
+∞
13.6
13
*
OAB72
NOMESCO Finland
Weight control and weight loss guidance
5.9
13.5
24
41
WX320
NOMESCO Finland
Spinalanesthesy
1.7
13.5
279
1768
A02BA02
ATC
ranitidine; systemic
1.9
13.5
201
1157
S01GX01
ATC
cromoglicic acid; ophthalmic
1.8
13.4
230
1382
WX402
NOMESCO Finland
General anaesthesia
1.6
13.4
332
2208
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.5
13.4
84
346
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.6
13.3
78
311
P01AB01
ATC
metronidazole; oral, rectal
1.6
13.3
423
2988
R52.2
ICD-10 Finland
Other chronic pain
2.9
13.1
61
215
N06AA12
ATC
doxepin; systemic
2.8
13.0
66
244
R35
ICD-10 Finland
Polyuria
2.2
13.0
112
530
G04CA02
ATC
tamsulosin; oral
1.6
13.0
417
2948
M04AA01
ATC
allopurinol; systemic
1.9
13.0
183
1035
N18.8
ICD-10 Finland
Other chronic renal failure
3.9
12.9
38
100
E29
ICD-10 Finland
Testicular dysfunction
13.1
12.9
22
17
M01AC06
ATC
meloxicam; systemic, rectal
1.6
12.9
448
3223
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.7
12.8
70
269
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
3.5
12.8
44
129
L08
ICPC
Shoulder symptom/complaint
1.6
12.8
316
2096
127
Kela drug reimbursment
Transplant complication
3.6
12.7
42
120
J01FF01
ATC
clindamycin; systemic
1.6
12.7
376
2606
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
12.7
399
2805
M02AA07
ATC
piroxicam; topical
1.6
12.6
402
2834
M79.1
ICD-10 Finland
Myalgia
1.8
12.6
196
1143
C10AA07
ATC
rosuvastatin; oral
1.5
12.6
489
3604
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
12.5
292
1907
C08CA01
ATC
amlodipine; oral
1.5
12.4
475
3484
J01FA09
ATC
clarithromycin; systemic
1.6
12.4
405
2869
G04BD12
ATC
mirabegron; oral
2.1
12.4
124
622
C08CA13
ATC
lercanidipine; oral
1.9
12.4
169
946
N05BA01
ATC
diazepam; systemic, rectal
1.9
12.3
169
947
J45
ICD-10 Finland
Asthma
2.0
12.3
130
666
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.6
12.3
71
281
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
12.2
73
294
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
12.1
180
1034
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
12.1
124
628
R03AK08
ATC
formoterol and beclometasone; inhalant
2.8
12.1
61
225
SPAT1094
SPAT
Continuous Positive Airway Pressure
4.3
12.0
31
74
N41.1
ICD-10 Finland
Chronic prostatitis
2.4
12.0
86
377
A98
ICPC
Health maint/preventive medicine
3.0
11.9
1453
13772
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.5
11.9
29
66
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
11.9
210
1270
UDC00
NOMESCO Finland
Ear microscopy
2.2
11.9
105
502
KFH50
NOMESCO Finland
Insertion of prosthetic replacement for testis
14.8
11.8
19
13
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.9
11.7
155
858
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
11.7
370
2597
L70.0
ICD-10 Finland
Acne vulgaris
3.4
11.7
42
127
P76
ICPC
Depressive disorder
2.2
11.7
99
466
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
11.6
569
4380
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
11.5
308
2079
SPAT1263
SPAT
Sampling
1.5
11.5
485
3622
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
35.3
11.3
14
*
M54.1
ICD-10 Finland
Radiculopathy
2.6
11.2
63
246
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.3
11.1
88
402
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.3
11.1
42
131
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.1
11.0
100
483
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.6
11.0
318
2182
XW000
NOMESCO Finland
Bone marrow biopsy
2.6
11.0
63
248
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
11.0
241
1547
A10BA02
ATC
metformin; oral
1.5
11.0
369
2622
UJF32
NOMESCO Finland
Coloscopy
1.6
10.9
305
2077
J01DA01
ATC
[U] cefalexin
1.4
10.9
791
6540
N06AG02
ATC
moclobemide; oral
2.6
10.9
62
244
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.1
10.9
108
541
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.8
10.8
54
198
N03AX09
ATC
lamotrigine; oral
2.3
10.8
84
381
C07AB12
ATC
nebivolol; oral
2.8
10.8
55
204
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
18.0
10.7
16
9
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.2
10.7
94
449
Y55
ICPC
Male Genital, Local injection/infiltration
60.4
10.6
12
*
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.1
10.6
106
532
R42
ICD-10 Finland
Dizziness and giddiness
1.7
10.5
231
1481
SBB10
NOMESCO Finland
Dental impressions
2.2
10.5
94
452
J45.1
ICD-10 Finland
Nonallergic asthma
2.3
10.5
82
373
X58
ICD-10 Finland
Exposure to other specified factors
1.6
10.5
273
1828
E23.05
ICD-10 Finland
Lack of TSH
110.8
10.4
11
*
2572A
ICD-9 Finland
Testicular dysfunction, Other testicular hypofunction
+∞
10.4
10
*
E23.03
ICD-10 Finland
Lack of ACTH
+∞
10.4
10
*
M01AH01
ATC
celecoxib; oral
1.7
10.4
195
1198
HMAK, ,
NOMESCO Finland
1.9
10.4
147
831
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
3.6
10.4
33
92
L17
ICPC
Foot/toe symptom/complaint
1.5
10.4
346
2450
D11
ICPC
Diarrhoea
1.8
10.3
157
909
9061/3-C62.9
ICD-O-3
Seminoma, NOS, of testis, NOS
10.7
10.3
19
18
F32.1
ICD-10 Finland
Moderate depressive episode
2.2
10.2
89
423
N04BC06
ATC
cabergoline; oral
23.5
10.2
14
6
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.9
10.2
131
717
R01AD11
ATC
triamcinolone; nasal
2.1
10.2
104
525
Z01.9
ICD-10 Finland
Special examination, unspecified
2.3
10.2
78
352
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
10.2
419
3099
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
4.1
10.2
27
66
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.2
10.1
81
372
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.1
10.1
94
459
R03AC03
ATC
terbutaline; inhalant
1.8
10.1
159
929
ZXA10
NOMESCO Finland
Bilateral
1.8
10.1
175
1052
OAB50, ,
SPAT
1.9
10.0
127
693
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.1
10.0
100
502
R05
ICD-10 Finland
Cough
1.6
10.0
249
1647
A02BC04
ATC
rabeprazole; oral
1.9
10.0
120
643
R06AE09
ATC
levocetirizine; oral
1.7
9.9
177
1073
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
9.9
160
943
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
9.8
100
506
J01MA14
ATC
moxifloxacin; systemic
1.9
9.8
123
670
75210
ICD-8 Finland
Congenital anomalies of genital organs, Undescended testicle
3.4
9.7
35
106
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
4.1
9.7
26
64
C09CA01
ATC
losartan; oral
1.5
9.7
318
2239
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
55.4
9.7
11
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
9.7
234
1537
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
9.6
1040
9147
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
9.6
197
1239
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
9.6
138
784
N50.9
ICD-10 Finland
Disorder of male genital organs, unspecified
4.0
9.6
27
69
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.8
9.6
145
837
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.7
9.6
176
1075
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.6
9.6
219
1418
F90.0
ICD-10 Finland
Disturbance of activity and attention
2.3
9.6
70
310
R03BA02
ATC
budesonide; inhalant
1.7
9.5
202
1282
R86.1
ICD-10 Finland
Abnormal findings in specimens from male genital organs, abnormal level of hormones
9.1
9.5
19
21
F34.1
ICD-10 Finland
Dysthymia
2.5
9.5
57
230
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
9.5
301
2103
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
9.5
134
757
SPAT1310
SPAT
Counselling related to known health issue
1.5
9.5
335
2396
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.3
9.5
74
337
R4110, ,
SPAT
1.8
9.4
141
811
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
100.7
9.4
10
*
G03GA05
ATC
follitropin alfa; parenteral
100.7
9.4
10
*
H05BX01
ATC
cinacalcet; oral
30.2
9.4
12
*
F32
ICD-10 Finland
Depressive episode
2.2
9.4
77
358
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
9.4
119
650
N03AE01
ATC
clonazepam; systemic
2.2
9.3
81
385
M54
ICD-10 Finland
Dorsalgia
1.7
9.3
189
1185
Y99
ICPC
Genital disease male other
7.0
9.3
22
32
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.8
9.3
140
807
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
9.3
122
674
C09DA03
ATC
valsartan and diuretics; oral
2.4
9.3
63
270
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.1
9.2
37
120
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
3.9
9.2
27
71
J01MA06
ATC
norfloxacin; oral
2.0
9.2
97
496
F52.2
ICD-10 Finland
Failure of genital response
2.1
9.2
86
421
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
9.2
96
490
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.2
9.1
80
382
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
9.1
268
1841
S18
ICPC
Laceration/cut
1.4
9.1
601
4834
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.7
9.1
159
959
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
9.0
132
754
L04AA06
ATC
mycophenolic acid; systemic
3.0
9.0
40
138
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
3.9
9.0
26
68
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.6
9.0
221
1456
SCA01
NOMESCO Finland
Preventive oral health care, short
1.5
9.0
352
2570
M05BA04
ATC
alendronic acid; oral
2.8
8.9
44
161
F51
ICD-10 Finland
Nonorganic sleep disorders
2.2
8.9
71
327
N06AA09
ATC
amitriptyline; systemic
2.0
8.9
89
448
J01MA01
ATC
ofloxacin; systemic
2.0
8.8
96
497
WX002
NOMESCO Finland
Sedation and analgesia
1.6
8.8
212
1388
ZXD05
NOMESCO Finland
Urgent procedure
1.5
8.8
352
2577
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.8
8.8
44
162
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
2.9
8.8
40
140
WX722
NOMESCO Finland
PEEP
2.1
8.8
80
388
Z3231
NOMESCO Finland
Registered nurse
1.5
8.7
331
2397
M01AX05
ATC
glucosamine; oral
1.8
8.7
136
792
R31
ICD-10 Finland
Unspecified haematuria
1.8
8.7
141
831
205
Kela drug reimbursment
Chronic hypertension
1.6
8.7
248
1691
C07AG02
ATC
carvedilol; oral
2.3
8.7
65
291
A04
ICPC
Weakness/tiredness general
1.7
8.7
150
901
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
8.6
345
2525
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
8.6
784
6634
C62.12
ICD-10 Finland
Malignant tumor of the descending testicle, embryonic carsinoma, teratocarcinoma or coriocarsinoma
10.1
8.5
16
16
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
8.5
378
2822
AA1AD
NOMESCO Finland
CT of head and brain
1.5
8.5
334
2435
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
2.0
8.5
97
511
L57.0
ICD-10 Finland
Actinic keratosis
2.0
8.5
87
441
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
27.7
8.5
11
*
T90
ICPC
Diabetes non-insulin dependent
1.5
8.5
319
2306
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
8.4
152
923
NA3BG, ,
SPAT
2.1
8.4
82
408
SPAT1325
SPAT
Vaccination
1.5
8.4
293
2084
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
90.6
8.4
9
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.3
8.4
65
295
R21
ICPC
Throat symptom/complaint
1.6
8.4
237
1611
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.4
8.4
58
251
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
8.4
522
4141
G04BD04
ATC
oxybutynin; oral, transdermal
2.9
8.4
38
133
Q53.9
ICD-10 Finland
Undescended testicle, unspecified
+∞
8.3
8
*
SPAT1377
SPAT
Polysomnography
2.5
8.3
52
215
J20
ICD-10 Finland
Acute bronchitis
1.8
8.3
128
744
P03
ICPC
Feeling depressed
1.8
8.3
122
699
7525A
ICD-9 Finland
Congenital anomalies of genital organs, Undescended testicle[RETENTIO TESTIS (CRYPTORCHISMUS)]
7.1
8.3
19
27
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
3.5
8.2
28
82
R01AD59
ATC
mometasone, combinations; nasal
1.9
8.2
105
575
R86.0
ICD-10 Finland
Abnormal findings in specimens from male genital organs, abnormal level of enzymes
2.5
8.2
52
216
N06AX05
ATC
trazodone; oral
2.8
8.2
39
140
J02AC02
ATC
itraconazole; systemic
1.6
8.2
183
1176
M01AC01
ATC
piroxicam; systemic, rectal
1.7
8.2
146
884
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.1
8.2
81
406
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
8.2
275
1942
E66
ICD-10 Finland
Obesity
2.0
8.2
83
420
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
8.1
180
1154
A10BK01
ATC
dapagliflozin; oral
1.8
8.1
126
733
R04.0
ICD-10 Finland
Epistaxis
2.0
8.1
93
491
C08CA02
ATC
felodipine; oral
2.0
8.1
91
477
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
8.1
305
2203
J34.2
ICD-10 Finland
Deviated nasal septum
1.8
8.1
126
734
A10BJ02
ATC
liraglutide; parenteral
2.6
8.1
44
170
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
2.0
8.1
85
436
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.6
8.1
45
176
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.9
8.0
96
514
M54.6
ICD-10 Finland
Pain in thoracic spine
1.9
8.0
107
594
V29.9
ICD-10 Finland
Motorcycle rider [any] injured in unspecified traffic accident
2.9
8.0
37
131
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.5
8.0
289
2071
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.6
8.0
171
1088
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
7.9
99
538
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.7
7.9
136
815
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.7
7.9
42
160
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.0
7.9
33
110
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
7.9
1010
8967
B01AB05
ATC
enoxaparin; parenteral
1.5
7.9
321
2354
GD1AA, ,
SPAT
1.5
7.8
285
2043
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
7.8
108
606
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
3.0
7.8
34
116
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.5
7.8
231
1586
R96
ICPC
Asthma
1.9
7.8
93
498
D07AC13
ATC
mometasone; topical
1.4
7.8
354
2650
A99
ICPC
Disease/condition unspecnature/site
1.8
7.8
119
690
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.0
7.8
79
400
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
7.8
627
5173
H02AB07
ATC
prednisone; oral
1.7
7.8
136
820
ZXA05
NOMESCO Finland
Left side
1.5
7.7
261
1842
N02AA05
ATC
oxycodone; systemic
1.6
7.7
187
1225
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
7.7
428
3319
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.7
925
8114
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
3.3
7.7
28
86
M43.1
ICD-10 Finland
Spondylolisthesis
2.5
7.6
47
193
M01AB55
ATC
diclofenac, combinations; oral
2.3
7.6
58
262
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
18.5
7.6
11
6
A06AD11
ATC
lactulose; oral
1.7
7.6
128
763
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.9
7.6
101
561
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
3.1
7.6
30
97
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.2
7.5
65
309
SPAT1281
SPAT
Other administrative function
1.9
7.5
87
461
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
7.5
110
629
A07DA03
ATC
loperamide; oral
2.7
7.5
39
147
S04
ICPC
Lump/swelling localized
1.8
7.5
119
697
C10AC01
ATC
colestyramine; oral
2.9
7.5
33
114
L02
ICPC
Back symptom/complaint
1.7
7.5
126
752
L01
ICPC
Neck symptom/complaint
1.6
7.4
175
1139
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
80.5
7.4
8
*
C02AC05
ATC
moxonidine; oral
2.2
7.4
58
265
A02BA03
ATC
famotidine; systemic
2.8
7.4
36
131
S76.4
ICD-10 Finland
Injury of other and unspecified muscles and tendons at thigh level
3.5
7.4
25
73
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
7.4
209
1420
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
7.4
1334
12528
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
7.3
129
779
E87.5
ICD-10 Finland
Hyperkalaemia
3.6
7.3
23
64
D10BA01
ATC
isotretinoin; oral
1.8
7.3
99
553
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.3
387
2973
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.3
7.3
51
222
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.0
7.3
32
110
E29.0
ICD-10 Finland
Testicular hyperfunction
+∞
7.3
7
*
G03GA02
ATC
human menopausal gonadotrophin; parenteral
+∞
7.3
7
*
G03GA06
ATC
follitropin beta; parenteral
+∞
7.3
7
*
F52.0
ICD-10 Finland
Lack or loss of sexual desire
6.9
7.3
17
25
SPAT1312
SPAT
General health counselling
1.4
7.3
330
2467
G44.2
ICD-10 Finland
Tension-type headache
1.7
7.3
133
812
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
2.4
7.2
48
204
D01AE15
ATC
terbinafine; topical
1.8
7.2
107
614
D07AD01
ATC
clobetasol; topical
1.6
7.2
185
1228
H02.3
ICD-10 Finland
Blepharochalasis
2.3
7.2
51
223
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.4
7.2
46
192
A01
ICPC
Pain general/multiple sites
1.8
7.2
106
607
Z3226
NOMESCO Finland
Physiotherapist
1.6
7.2
195
1311
R39.1
ICD-10 Finland
Other difficulties with micturition
2.2
7.2
57
262
A69
ICPC
General and Unspecified, Other reason for encounter NEC
2.7
7.2
37
139
R01AD01
ATC
beclometasone; nasal
1.6
7.2
181
1198
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
7.2
132
807
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
30.2
7.2
9
*
XA420
NOMESCO Finland
Extensive sleep examination
3.5
7.1
24
70
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
1.8
7.1
96
536
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
7.1
131
802
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.2
7.1
55
251
Z01.7
ICD-10 Finland
Laboratory examination
1.5
7.1
209
1434
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.7
7.0
128
780
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.7
7.0
125
757
R06AX13
ATC
loratadine; oral
1.6
7.0
164
1066
SPAT1255
SPAT
Intravenous administration of medicine
1.9
7.0
83
444
R52.9
ICD-10 Finland
Pain, unspecified
1.7
7.0
129
790
A97
ICPC
No disease
1.5
7.0
221
1539
D07AC01
ATC
betamethasone; topical
1.4
7.0
446
3533
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
1.9
6.9
89
489
R13
ICD-10 Finland
Dysphagia
2.0
6.9
77
403
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.8
6.9
94
526
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
6.9
336
2542
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
6.9
205
1409
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.4
6.8
44
185
L82
ICD-10 Finland
Seborrhoeic keratosis
1.5
6.8
191
1295
M54.2
ICD-10 Finland
Cervicalgia
1.8
6.8
109
641
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.5
6.8
41
167
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.9
6.8
84
456
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.7
6.8
127
780
OAA81, ,
SPAT
2.1
6.8
63
309
M01AH02
ATC
rofecoxib; oral
1.7
6.8
117
703
R00.2
ICD-10 Finland
Palpitations
1.9
6.8
81
435
E26.0
ICD-10 Finland
Primary hyperaldosteronism
40.2
6.8
8
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
6.8
118
711
KFA00
NOMESCO Finland
Exploration of testis
4.3
6.8
17
40
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.9
6.8
80
428
M77.1
ICD-10 Finland
Lateral epicondylitis
1.7
6.7
136
852
E03
ICD-10 Finland
Other hypothyroidism
2.6
6.7
37
144
A06AC51
ATC
ispaghula, combinations; oral
2.3
6.7
47
205
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
6.7
274
2005
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
2.5
6.7
39
156
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.5
6.7
40
162
R06AX18
ATC
acrivastine; oral
2.9
6.7
31
110
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.3
6.7
24
73
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.0
6.7
66
331
E000002, ,
ATC
1.7
6.6
116
699
G03BB01
ATC
mesterolone; oral
6.5
6.6
16
25
K59.1
ICD-10 Finland
Functional diarrhoea
2.1
6.6
61
298
A10BJ06
ATC
semaglutide; parenteral
1.8
6.6
91
511
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
5.5
6.6
18
33
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.8
6.6
106
624
196
Kela drug reimbursment
Paricalcitol and cinacalcet
12.3
6.6
11
9
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
6.6
169
1123
ZXD00
NOMESCO Finland
Emergency procedure
2.6
6.6
36
140
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.6
6.6
157
1026
L29
ICPC
Musculoskeletal sympt/complt other
1.8
6.5
90
506
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.6
6.5
164
1085
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
2.8
6.5
31
112
L86
ICPC
Back syndrome with radiating pain
1.9
6.5
75
398
A11CC03
ATC
alfacalcidol; systemic
2.9
6.5
29
101
R03BA01
ATC
beclometasone; inhalant
1.6
6.5
140
892
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.7
6.5
109
650
SAA04
NOMESCO Finland
Special examination of mouth
2.0
6.5
68
349
L03AA02
ATC
filgrastim; parenteral
2.5
6.5
40
165
N06AX18
ATC
reboxetine; oral
3.9
6.4
18
46
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
3.9
6.4
18
46
J31.0
ICD-10 Finland
Chronic rhinitis
1.7
6.4
110
659
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
6.4
56
268
J35.0
ICD-10 Finland
Chronic tonsillitis
2.1
6.4
60
295
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.3
6.4
23
70
R05FB02
ATC
cough suppressants and expectorants; systemic
1.4
6.4
363
2812
QXB99, ,
SPAT
2.4
6.4
41
172
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
6.4
342
2624
KGH10
NOMESCO Finland
Operation for phimosis
1.9
6.4
74
393
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
2.3
6.4
45
197
9061/3-C62.1
ICD-O-3
Seminoma, NOS, of descended testis
14.4
6.4
10
7
OAB50
NOMESCO Finland
Delivery of care equipment and instruction on their use
2.9
6.4
29
102
XF602
NOMESCO Finland
Bloodpressure monitoring
4.1
6.4
17
42
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.0
6.3
63
317
ACC51
NOMESCO Finland
Release of median nerve
1.8
6.3
84
467
P01
ICPC
Feeling anxious/nervous/tense
1.6
6.3
129
811
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
6.3
124
772
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
2.7
6.3
32
120
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
1.8
6.3
83
461
R30.0
ICD-10 Finland
Dysuria
2.1
6.3
56
271
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.2
6.3
53
251
301
Kela drug reimbursment
Growth hormone
+∞
6.3
6
*
E23.2
ICD-10 Finland
Diabetes insipidus
+∞
6.3
6
*
E23.06
ICD-10 Finland
Empty sella
+∞
6.3
6
*
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.8
6.2
96
558
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
6.2
147
957
T81.9
ICD-10 Finland
Unspecified complication of procedure
3.0
6.2
26
87
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
6.2
282
2101
TQW40, ,
SPAT
1.6
6.2
128
806
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.8
6.2
85
477
F41.00
ICD-10 Finland
Moderate panic disorder
3.2
6.2
24
77
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.5
6.2
176
1197
XX9TE
NOMESCO Finland
Compementary ultrasound examination
5.8
6.1
16
28
D82
ICPC
Teeth/gum disease
1.3
6.1
488
3982
ABC30
NOMESCO Finland
Decompression of cervical nerve roots
3.8
6.1
18
48
-1, ,
ICPC
2.4
6.1
40
170
WX290
NOMESCO Finland
Other blockage of nerve
1.3
6.1
709
6100
N50.0
ICD-10 Finland
Atrophy of testis
12.6
6.1
10
8
E000006, ,
ATC
2.1
6.1
53
254
Z00.0
ICD-10 Finland
General medical examination
1.5
6.1
225
1615
SPAT1301
SPAT
No procedures
1.4
6.1
304
2305
A44
ICPC
General and Unspecified, Preventive immunization/medic
1.7
6.0
119
741
R99
ICPC
Respiratory disease other
2.7
6.0
30
111
321
Kela drug reimbursment
Paricalcitol and cinacalcet
10.1
6.0
11
11
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
6.0
104
625
B35.3
ICD-10 Finland
Tinea pedis
1.9
6.0
76
416
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.3
6.0
43
190
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
487
338
20.89
307.65
1.7
1.4
246.95
254.58
mu/l
0.15
464
319
281
181
18.89
307.65
2.1
1.5
13.94
7.69
iu/l
4.62
213
134
884
959
21.13
307.65
3.6
1.6
213.89
225.74
pmol/l
1.52
872
913
668
487
24.00
307.65
2.1
1.4
7.64
4.76
u/l
8.59
544
392
1347
2827
39.26
307.65
6.8
2.1
13.26
15.00
nmol/l
12.07
1298
2642
978
1193
21.84
307.65
3.5
1.7
30.10
37.55
nmol/l
22.30
969
1162
147
74
21.92
194.14
2.0
1.4
0.13
0.12
nmol/l
0.70
114
49
1351
8223
7.72
153.08
5.6
4.2
1.37
1.88
ug/l
9.62
1288
7611
399
1036
4.89
145.65
2.5
2.1
364.27
373.82
nmol/l
0.46
379
972
211
301
8.00
143.89
1.7
1.3
178.46
210.54
pmol/l
0.49
211
301
1092
6523
3.51
103.91
4.3
3.5
22.63
21.00
%
2.60
428
2530
892
5035
2.91
87.64
3.4
2.7
0.63
0.68
ug/l
1.02
482
2689
99
108
9.75
83.01
1.8
1.3
321.28
279.82
mu/l
0.49
87
88
1228
8404
3.59
82.98
4.4
3.1
14.42
14.74
pmol/l
4.80
1171
7807
846
4832
2.73
78.05
3.6
2.7
162.71
192.48
ug/l
2.39
802
4603
70
51
14.35
76.23
1.5
1.2
18.98
10.88
u/l
1.82
58
40
1357
10753
3.86
55.17
5.6
3.9
1.79
1.87
mu/l
1.94
1306
10064
758
4662
2.27
51.99
3.0
2.3
76.91
71.28
nmol/l
6.30
713
4333
69
97
7.41
46.87
6.5
4.9
4.42
37.72
u/l
1.03
19
16
1201
9349
2.45
41.77
9.5
8.7
73.47
78.45
u/l
4.11
1164
9020
718
4714
2.01
37.36
2.2
2.0
96.35
94.39
pmol/l
0.63
420
2793
358
1810
2.29
37.13
3.3
2.6
2.40
2.31
g/l
2.64
326
1699
339
1681
2.32
36.77
3.4
2.6
26.34
25.12
%
0.70
312
1595
371
1933
2.22
35.60
3.4
2.6
15.34
14.29
umol/l
1.33
343
1829
42
45
9.57
35.46
4.8
4.6
6.48
10.72
pmol/l
0.30
12
17
1124
8765
2.14
34.82
4.8
4.0
7.96
9.17
mm/h
2.76
1085
8339
82
198
4.32
31.16
1.1
1.1
—
—
—
0
0
436
2526
2.03
31.07
1.3
1.3
2.06
1.98
u/ml
0.03
144
747
863
6276
1.89
30.83
7.2
7.6
12.58
12.98
umol/l
0.34
832
6050
98
272
3.79
30.80
1.3
1.3
15.65
41.82
u/l
1.55
92
234
1400
12226
3.31
30.34
7.4
5.8
39.57
39.29
mmol/mol
0.57
1357
11750
737
5117
1.87
30.27
6.0
6.0
37.34
36.53
g/l
3.81
711
4862
790
5610
1.87
30.17
2.2
1.9
1.72
1.57
mmol/l
2.78
672
4911
541
3414
1.92
29.81
3.2
3.7
2.35
2.35
mmol/l
0.19
511
3166
960
7269
1.90
29.74
6.9
6.1
6.77
6.83
mmol/l
0.32
921
6997
777
5529
1.84
29.08
15.8
11.5
0.06
0.00
e9/l
0.50
683
4549
31
29
10.89
28.72
1.7
1.1
6.75
4.62
umol/l
1.38
20
22
677
4669
1.82
27.58
3.7
3.8
33.75
40.18
u/l
1.12
644
4422
408
2416
1.95
26.68
1.7
1.5
2.37
2.68
g/l
3.60
300
1679
881
6632
1.80
26.26
4.4
3.6
394.07
305.72
e6/l
0.08
15
86
178
762
2.52
26.25
5.7
3.8
1.22
1.22
mmol/l
0.22
162
683
753
5422
1.78
26.03
10.3
8.4
1.21
1.20
mmol/l
2.07
628
4802
825
6127
1.77
25.40
3.8
3.2
0.01
0.30
estimate
0.49
205
1053
917
7023
1.79
25.39
10.1
11.2
4.34
4.16
e9/l
0.45
830
6112
816
6043
1.77
25.35
3.8
3.1
0.00
0.00
estimate
-0.00
227
1182
1393
12351
2.89
25.02
18.9
13.7
83.69
88.37
ml/min/173m2
15.15
1328
11405
129
482
2.83
24.89
3.3
3.1
1.40
1.37
mg/l
0.13
120
457
821
6110
1.76
24.89
3.8
3.1
0.00
8.11
estimate
1.82
223
1174
552
3664
1.80
24.84
3.1
2.7
375.14
369.97
umol/l
0.69
507
3375
535
3537
1.80
24.28
3.2
2.6
0.03
0.10
estimate
0.56
189
933
1451
13209
4.42
24.14
7.2
5.4
2.67
2.81
mmol/l
7.92
1406
12636
645
4517
1.75
23.90
4.2
3.7
9.75
9.34
mmol/l
1.04
557
3956
682
4857
1.74
23.77
9.9
8.1
1.20
1.20
mmol/l
1.46
645
4580
1439
13063
3.76
23.35
6.6
4.9
1.17
1.28
mmol/l
33.66
1392
12491
1410
12666
3.01
23.04
22.9
17.0
139.64
139.74
mmol/l
0.97
1396
12460
1414
12737
3.06
22.67
23.2
17.1
4.04
4.01
mmol/l
3.74
1399
12514
1256
10765
2.05
22.64
23.6
17.9
13.64
13.43
%
5.92
1246
10637
1440
13108
3.73
22.63
6.7
4.9
4.42
4.62
mmol/l
11.99
1398
12593
411
2554
1.84
22.58
2.6
2.2
3.07
2.74
mg/l
1.85
357
2246
1398
12531
2.80
22.41
5.5
4.2
1.64
1.47
mmol/l
7.65
1347
11930
130
517
2.66
22.22
3.1
4.0
4.76
4.71
pmol/l
0.23
123
479
1475
13691
7.08
21.69
15.1
11.4
36.08
33.81
u/l
4.03
1454
13441
1354
12000
2.37
21.52
5.8
4.6
6.05
6.04
mmol/l
0.01
1287
11308
1395
12541
2.70
21.28
19.7
14.6
21.87
25.63
mg/l
4.92
1216
10224
586
4092
1.71
21.24
4.9
4.3
9.40
8.47
mg/mmol
0.20
405
2824
661
4774
1.69
21.09
3.6
3.0
0.02
0.01
estimate
0.30
201
1016
435
2807
1.78
20.81
1.9
1.6
19.17
18.51
nmol/l
0.48
386
2460
403
2549
1.80
20.60
3.2
2.5
2.00
2.53
e6/l
1.83
370
2340
264
1469
1.97
20.10
5.3
5.1
233.80
237.18
u/l
0.11
251
1407
486
3265
1.72
20.03
4.0
3.1
0.30
0.41
e6/l
0.73
376
2368
657
4786
1.67
19.94
4.0
3.4
28.09
46.23
ng/l
1.96
463
3202
548
3813
1.69
19.78
4.0
3.2
71.42
103.98
e6/l
0.36
435
2924
1195
10218
1.85
19.63
4.2
3.6
55.11
54.81
u/l
0.05
1148
9850
79
256
3.20
19.55
3.9
4.4
2.23
2.22
mmol/l
0.01
54
165
79
257
3.19
19.42
3.9
4.4
4.98
5.05
kpa
0.39
79
251
734
5557
1.63
18.73
13.0
12.9
1.18
1.22
inr
1.18
628
4643
215
1140
2.03
18.68
3.9
3.2
—
—
—
0
0
281
1633
1.89
18.68
9.6
7.4
1.03
1.02
mmol/l
0.03
269
1566
548
3874
1.65
18.26
2.9
3.0
55.60
60.74
u/l
1.76
511
3681
269
1556
1.89
18.10
2.8
3.1
132.85
161.08
ug/g
0.71
242
1326
342
2132
1.78
18.05
1.8
1.7
55067987.58
23564875.05
pmol/l
0.34
296
1846
257
1469
1.91
17.92
2.4
2.2
—
—
—
0
0
417
2770
1.70
17.48
2.0
1.9
0.92
1.13
mg/l
0.91
319
2061
464
3176
1.67
17.34
3.2
3.2
873.03
1162.86
ng/l
1.04
352
2640
526
3730
1.63
17.04
2.7
2.4
273.66
346.16
u/l
0.79
504
3574
267
1596
1.82
16.03
2.5
2.2
—
—
—
0
0
146
718
2.15
15.40
3.4
3.1
1.45
1.54
mmol/l
0.15
106
534
72
255
2.92
15.32
3.2
2.6
18.38
17.24
%
1.61
72
247
453
3169
1.62
15.14
3.8
3.4
0.01
0.01
estimate
0.26
209
1061
116
523
2.32
15.11
1.2
1.2
65.54
123.74
u/ml
1.66
38
171
330
2136
1.70
14.91
4.6
4.3
0.83
0.82
mmol/l
0.73
319
2052
200
1123
1.90
14.56
2.8
2.6
10.12
10.79
g/l
1.71
175
1038
294
1888
1.69
13.55
1.4
1.3
19.70
28.37
iu/ml
0.93
81
545
21
15
14.18
12.76
1.3
1.5
1.57
1.47
%
0.41
21
15
168
932
1.90
12.63
9.0
11.9
24.79
24.91
mmol/l
0.16
168
925
1480
14166
5.78
12.40
31.9
21.5
233.98
239.69
e9/l
3.39
1466
13931
163
901
1.91
12.39
2.2
3.0
67.50
66.99
g/l
0.46
155
857
1480
14175
5.71
12.19
31.8
21.4
90.37
90.49
fl
0.49
1475
14064
1480
14178
5.68
12.12
32.7
22.2
44.39
43.73
%
0.59
1475
14058
1480
14179
5.67
12.10
31.9
21.4
4.96
4.78
e12/l
25.66
1464
13922
123
622
2.07
12.04
5.9
4.5
108.48
93.93
ng/l
0.53
107
567
1480
14182
5.65
12.03
32.1
21.6
149.84
144.93
g/l
24.39
1475
14071
1480
14185
5.63
11.96
31.9
21.5
6.83
6.66
e9/l
0.52
1463
13925
1020
8831
1.49
11.17
3.2
2.9
—
—
—
0
0
72
307
2.41
10.67
3.5
2.8
8.93
8.22
kpa
3.31
72
302
204
1265
1.71
10.54
11.3
8.7
9.46
9.01
mmol/l
0.46
197
1224
90
426
2.18
10.47
3.4
3.3
—
—
—
0
0
166
979
1.78
10.23
3.6
3.1
75.72
71.16
e9/l
0.74
119
714
647
5198
1.43
10.17
3.0
2.8
—
—
estimate
—
0
0
228
1475
1.64
10.01
1.8
1.7
1220.95
1145.69
nmol/l
0.61
166
1169
324
2280
1.54
9.95
1.5
1.5
—
—
—
0
0
272
1840
1.58
9.94
2.7
3.5
2.43
2.43
mmol/l
0.22
252
1666
97
484
2.07
9.86
1.9
1.9
4.31
5.20
mg/l
0.18
68
362
107
554
2.00
9.84
1.1
1.1
—
—
—
0
0
74
335
2.27
9.60
2.5
2.0
—
—
—
0
0
79
368
2.21
9.57
3.5
3.4
—
—
—
0
0
51
195
2.67
9.49
2.1
1.8
1.54
1.69
mmol/l
0.75
51
189
64
274
2.40
9.43
3.0
2.3
144.87
136.76
g/l
1.28
55
214
75
347
2.22
9.25
2.5
2.0
—
—
—
0
0
56
229
2.50
9.11
2.7
2.1
—
—
—
0
0
274
1902
1.54
8.86
2.5
2.0
—
—
—
0
0
251
1714
1.56
8.73
1.3
1.3
8.70
8.20
u/ml
0.04
108
738
31
98
3.21
8.11
2.3
1.9
—
—
—
0
0
25
69
3.67
8.03
1.1
1.2
109.12
105.87
pmol/l
0.15
25
69
38
139
2.78
7.74
2.9
2.6
33.42
33.53
pg
0.07
38
139
73
362
2.07
7.59
8.4
7.4
164.14
1064.61
iu/ml
1.40
14
49
137
834
1.71
7.54
2.3
2.4
11.96
17.31
au/ml
0.71
13
115
69
342
2.07
7.20
1.4
1.5
306.37
261.41
ug/g
0.90
45
202
109
630
1.79
7.20
1.9
2.2
41.41
40.18
u/l
0.23
99
566
15
20
7.56
6.90
1.1
1.1
—
—
—
0
0
42
172
2.48
6.88
2.5
1.9
—
—
—
0
0
14
18
7.84
6.61
1.3
1.1
92.93
100.06
nmol/24h
0.14
14
18
130
812
1.66
6.52
1.4
1.3
100.13
340.80
u/ml
4.53
124
759
129
807
1.66
6.43
1.5
1.7
—
—
—
0
0
416
3299
1.36
6.34
5.1
4.9
89.21
88.10
%
0.45
407
3251
148
964
1.59
6.27
2.0
2.1
0.27
0.35
mg/l
1.13
82
569
41
174
2.39
6.25
2.2
1.8
—
—
—
0
0
63
321
2.00
6.14
1.4
1.5
187.40
1119.87
e6/l
0.92
55
237
62
315
2.01
6.10
1.3
1.4
12.42
25.13
e6/l
0.43
50
215
124
788
1.63
5.82
1.3
1.3
26.14
59.68
au/ml
—
5
58
73
399
1.87
5.82
1.4
1.3
—
—
—
0
0
44
201
2.23
5.70
2.2
1.6
—
—
—
0
0
26
92
2.86
5.69
2.8
1.7
—
—
—
0
0
59
304
1.98
5.60
2.0
1.6
—
—
—
0
0
212
1529
1.45
5.57
3.5
3.4
7.55
8.99
umol/l
0.51
194
1376
52
257
2.06
5.53
1.9
1.7
—
—
—
0
0
260
1956
1.40
5.40
3.7
3.0
0.41
0.49
e6/l
0.26
128
946
63
339
1.90
5.29
3.5
3.5
34.09
40.86
mg/l
0.38
48
280
67
374
1.83
5.03
1.9
1.8
—
—
—
0
0
40
186
2.18
5.00
1.1
1.1
2.18
2.49
eliau/ml
0.12
20
94
174
1236
1.46
4.95
2.7
2.5
0.24
0.22
g/l
1.14
166
1151
62
340
1.86
4.93
3.5
3.5
53.64
70.63
mg/l
0.33
47
280
58
313
1.89
4.85
1.1
1.1
1.52
8.82
eliau/ml
—
10
40
190
1381
1.43
4.78
2.5
1.9
—
—
—
0
0
56
301
1.89
4.75
1.8
2.7
0.00
0.00
g/l
-0.00
49
268
197
1450
1.41
4.62
2.4
1.8
—
—
—
0
0
88
547
1.65
4.56
1.6
1.7
1.49
1.51
g/l
0.05
77
473
46
237
1.97
4.43
1.2
1.1
40.34
12.94
au/ml
0.36
17
84
270
2107
1.34
4.42
3.7
2.9
0.46
0.77
e6/l
2.23
141
1103
25
100
2.53
4.39
2.0
1.6
2701923.80
1739038.90
iu/ml
—
5
10
62
354
1.78
4.37
2.2
2.6
0.56
0.98
g/l
0.52
57
320
36
170
2.15
4.37
1.4
1.2
—
—
—
0
0
345
2795
1.30
4.34
2.7
2.6
—
—
—
0
0
47
247
1.93
4.29
2.2
1.5
—
—
—
0
0
174
1272
1.42
4.25
6.1
4.3
1.83
1.77
mmol/l
0.08
152
1095
18
62
2.93
4.17
3.8
5.8
81.73
66.34
mg/l
0.28
11
47
8
10
8.04
4.06
1.0
1.6
—
—
—
0
0
329
2679
1.29
3.95
2.0
2.1
1.47
1.52
%
0.60
294
2413
25
106
2.38
3.91
1.7
1.3
—
—
—
0
0
279
2225
1.31
3.91
2.5
2.1
4.22
3.96
ratio
1.95
233
1744
54
308
1.78
3.85
3.6
3.4
3.42
2.26
ratio
0.34
24
165
19
71
2.70
3.83
2.8
1.8
—
—
—
0
0
71
439
1.65
3.80
1.7
1.8
—
—
—
0
0
16
56
2.88
3.63
3.1
3.0
—
—
—
0
0
16
56
2.88
3.63
3.1
3.0
—
—
—
0
0
16
56
2.88
3.63
3.1
3.0
—
—
—
0
0
16
56
2.88
3.63
3.1
3.0
—
—
—
0
0
49
277
1.80
3.62
1.1
1.1
261.50
91.28
iu/ml
—
8
71
212
1646
1.34
3.58
2.0
1.7
3.47
3.60
mmol/l
0.86
168
1138
174
1311
1.37
3.57
5.9
4.2
5.90
5.86
kpa
0.23
166
1275
149
1096
1.40
3.53
4.4
3.5
5.42
4.70
kpa
1.88
144
1065
134
969
1.42
3.50
2.3
2.4
0.24
0.32
e6/l
0.41
126
928
20
81
2.49
3.47
2.7
1.8
193.90
198.89
u/l
0.14
20
81
29
139
2.11
3.44
3.4
2.8
7.20
7.12
mmol/l
0.05
24
124
20
83
2.43
3.31
1.0
1.1
0.87
1.10
u/l
—
6
40
18
71
2.55
3.30
2.8
1.8
—
—
—
0
0
131
956
1.41
3.27
1.4
1.5
—
—
—
0
0
69
443
1.58
3.22
1.8
1.7
5.30
5.68
iu/ml
0.07
14
114
54
329
1.67
3.11
1.1
1.1
3.23
2.05
u/ml
0.28
30
171
297
2457
1.26
3.10
3.6
3.9
652.37
604.49
ng/l
0.05
225
1903
167
1281
1.34
3.07
5.5
4.5
27.60
28.71
%
0.72
129
905
19
80
2.39
3.06
2.7
1.7
—
—
—
0
0
113
814
1.42
3.05
6.9
4.1
24.25
24.22
mmol/l
0.04
113
808
48
285
1.71
3.04
1.0
1.1
1.29
1.90
u/ml
0.22
20
128
30
154
1.97
3.01
2.4
2.1
—
—
—
0
0
23
108
2.15
2.91
2.6
2.2
—
—
—
0
0
23
108
2.15
2.91
2.6
2.2
—
—
—
0
0
23
108
2.15
2.91
2.6
2.2
—
—
—
0
0
19
83
2.31
2.84
1.1
1.2
5.16
8.57
mm/h
1.55
19
83
41
240
1.73
2.76
1.3
1.5
—
—
—
0
0
48
294
1.65
2.74
1.0
1.1
3.18
6.60
u/ml
1.73
28
166
55
349
1.60
2.73
1.9
1.8
—
—
—
0
0
130
978
1.36
2.73
2.2
2.6
66.71
74.22
ml/min/173m2
1.10
59
364
54
342
1.60
2.71
1.3
1.1
3.04
3.24
0.18
14
77
27
140
1.95
2.66
2.5
2.2
—
—
—
0
0
70
476
1.49
2.58
1.2
1.1
—
0.72
—
0
5
21
101
2.09
2.53
1.9
1.5
81.33
85.04
umol/l
0.50
21
101
51
325
1.59
2.51
2.6
2.3
282.70
131.56
ug/min
0.42
32
202
19
88
2.17
2.51
1.2
1.3
1.84
1.32
nmol/l
0.63
14
66
194
1564
1.28
2.51
11.0
11.1
0.81
0.78
mmol/l
0.03
173
1305
20
95
2.12
2.49
2.2
2.3
868.73
648.50
ml
0.98
11
60
50
319
1.59
2.46
1.8
1.6
149.78
144.01
au/ml
0.11
15
95
58
384
1.53
2.43
2.6
2.1
—
—
—
0
0
52
339
1.55
2.35
1.3
1.4
—
—
—
0
0
47
300
1.59
2.32
1.7
1.7
—
—
—
0
0
93
682
1.39
2.32
2.1
1.6
—
—
—
0
0
12
47
2.57
2.27
3.6
3.3
—
—
—
0
0
12
47
2.57
2.27
3.6
3.3
—
—
—
0
0
53
351
1.53
2.24
1.4
2.0
1.07
0.91
nmol/l
0.97
45
309
22
114
1.94
2.21
1.4
1.1
10.16
25.16
u/ml
—
8
49
109
828
1.34
2.20
4.4
3.7
137.03
135.82
g/l
0.18
104
810
12
48
2.51
2.18
3.6
3.2
—
—
—
0
0
48
313
1.55
2.18
1.5
1.4
—
—
—
0
0
24
129
1.87
2.17
1.3
1.6
59.54
59.22
%
0.01
13
90
18
87
2.08
2.17
1.1
1.4
2.83
1.58
u/ml
—
8
52
22
115
1.93
2.16
1.0
1.1
—
—
—
0
0
47
309
1.54
2.07
1.2
1.2
—
—
—
0
0
47
309
1.54
2.07
1.2
1.2
—
—
—
0
0
168
1369
1.26
2.02
12.4
12.1
130.02
127.52
g/l
0.63
162
1340
48
321
1.51
1.97
1.6
1.3
—
—
—
0
0
29
171
1.71
1.97
1.1
1.1
3.67
2.66
—
6
48
18
91
1.99
1.95
1.2
1.3
0.58
0.54
ratio
0.17
11
46
6
16
3.76
1.93
13.7
6.7
6.15
5.58
mmol/l
—
6
16
46
308
1.51
1.89
2.2
3.0
2.00
2.07
index
0.04
30
185
22
121
1.83
1.89
2.4
2.1
—
—
—
0
0
14
65
2.16
1.88
1.1
1.1
161.76
256.92
iu/ml
0.84
14
65
174
1438
1.24
1.86
11.7
11.6
95.69
95.90
%
0.24
167
1390
188
1568
1.23
1.84
11.4
11.2
12.15
12.43
kpa
0.27
183
1519
188
1568
1.23
1.84
11.5
11.2
5.26
5.11
kpa
1.17
183
1518
43
286
1.52
1.83
1.0
1.1
2.67
1.95
u/ml
0.13
19
141
25
145
1.74
1.82
1.0
1.1
—
—
—
0
0
9
35
2.58
1.80
1.1
1.1
—
—
—
0
0
105
822
1.30
1.76
2.9
2.9
173.56
152.12
ng/l
0.18
91
724
20
110
1.83
1.73
1.0
1.4
1.69
1.97
mmol/l
2.62
20
104
17
89
1.92
1.70
3.4
3.1
650.00
977.62
u/ml
0.57
17
89
12
55
2.19
1.67
2.3
1.9
2.25
1.85
umol/l
1.19
12
50
308
2724
1.16
1.59
3.6
3.2
1.02
1.02
kg/l
0.21
218
1774
26
160
1.64
1.56
1.2
1.1
—
—
—
0
0
14
71
1.98
1.54
1.1
1.3
—
64.71
%
—
0
7
38
257
1.49
1.54
1.0
1.1
0.86
3.62
u/ml
2.08
18
136
21
123
1.72
1.51
3.1
3.1
39.08
39.34
%
0.02
12
56
11
51
2.17
1.50
1.4
2.0
—
—
—
0
0
36
242
1.50
1.50
1.0
1.1
3.07
3.77
u/ml
0.13
16
120
11
52
2.12
1.44
1.1
1.1
—
—
—
0
0
14
73
1.93
1.44
2.5
1.3
9.22
8.75
ug/l
0.04
14
66
34
229
1.50
1.42
1.3
2.1
1.89
4.17
iu/l
—
10
101
69
528
1.32
1.41
4.4
4.0
25.50
25.08
mmol/l
0.45
62
507
68
524
1.31
1.33
1.2
1.3
—
—
—
0
0
50
369
1.37
1.31
1.4
1.3
274.27
258.02
u/ml
0.16
30
233
150
1273
1.20
1.28
3.1
3.0
32.81
79.77
u/l
0.71
134
1134
12
62
1.94
1.28
3.2
2.3
—
—
—
0
0
9
44
2.05
1.27
1.7
1.2
40.58
40.96
g/l
—
9
44
33
229
1.45
1.22
1.0
1.1
0.16
1.16
u/ml
—
10
83
13
71
1.84
1.19
2.2
1.9
0.42
1.91
u/ml
—
6
21
15
86
1.75
1.19
1.1
1.3
—
—
—
0
0
25
166
1.51
1.15
1.0
1.1
—
—
—
0
0
36
260
1.39
1.10
1.1
1.1
1.46
1.47
g/l
0.02
36
238
5
21
2.39
1.09
1.0
1.1
—
—
—
0
0
14
81
1.74
1.09
1.2
1.2
—
—
—
0
0
18
112
1.61
1.09
2.4
2.7
—
—
—
0
0
8
41
1.96
1.09
6.4
2.7
161.07
119.63
ng/l
—
8
41
7
33
2.13
1.05
1.0
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
55
428
1.30
1.05
3.7
3.3
0.32
0.30
iu/ml
0.15
25
216
12
67
1.80
1.04
2.7
1.5
—
—
—
0
0
30
212
1.42
1.04
1.5
1.3
—
—
—
0
0
30
212
1.42
1.04
1.5
1.3
—
—
—
0
0
5
22
2.28
1.03
1.0
1.1
—
—
—
0
0
7
34
2.06
1.03
6.3
4.6
3.71
4.91
ug/l
—
7
34
32
230
1.40
1.02
1.3
1.2
—
—
—
0
0
40
299
1.35
1.01
1.7
1.7
—
—
—
0
0
10
53
1.89
1.01
1.6
2.4
—
55714.38
—
0
8
12
68
1.77
1.00
2.7
1.5
—
—
—
0
0
46
353
1.31
0.98
1.3
1.3
145.12
182.13
miu/ml
0.29
14
131
36
266
1.36
0.98
1.2
1.1
—
—
—
0
0
57
451
1.27
0.98
3.1
2.9
—
—
—
0
0
9
50
1.80
0.96
3.6
2.4
0.61
0.61
mmol/l
—
9
50
112
955
1.19
0.96
14.7
14.0
1.34
1.42
%
0.30
112
948
5
101
0.49
0.89
4.8
2.4
122.00
138.92
nmol/l
—
5
87
11
64
1.72
0.86
2.4
1.9
22.27
25.38
umol/l
1.23
11
59
75
624
1.21
0.85
1.5
1.4
—
—
—
0
0
6
33
1.82
0.79
1.5
1.0
—
—
—
0
0
9
54
1.67
0.74
7.1
3.5
1.94
1.23
%
—
9
54
7
38
1.85
0.73
2.0
1.3
0.32
0.29
g/l
—
7
33
34
263
1.30
0.73
1.5
1.3
2.15
4.98
u/ml
1.22
13
97
26
193
1.35
0.73
1.3
1.6
1.59
1.45
promille
0.16
15
154
9
56
1.61
0.72
3.2
1.6
—
—
—
0
0
9
56
1.61
0.72
3.2
1.6
—
—
—
0
0
25
185
1.36
0.72
2.5
2.3
19.70
24.20
iu/ml
—
7
18
9
57
1.58
0.71
4.8
3.9
—
—
—
0
0
9
58
1.56
0.69
2.8
3.3
15.67
429.07
ug/l
—
9
52
16
110
1.46
0.68
2.2
2.5
22.62
19.17
mg/l
—
5
46
19
136
1.40
0.67
1.5
1.3
285.64
286.28
mosm/kgh2o
0.05
14
100
5
28
1.79
0.66
1.2
1.7
—
—
—
0
0
18
128
1.41
0.65
2.1
1.7
—
—
—
0
0
18
128
1.41
0.65
2.1
1.7
—
—
—
0
0
18
129
1.40
0.63
2.1
1.7
—
—
—
0
0
8
50
1.60
0.61
1.6
1.2
—
65.00
—
0
6
8
51
1.57
0.60
1.1
1.1
—
—
—
0
0
8
51
1.57
0.60
1.4
1.1
—
—
—
0
0
11
72
1.53
0.59
2.2
3.4
1.27
0.94
index
0.50
11
72
6
35
1.72
0.57
1.0
1.1
—
—
—
0
0
18
132
1.37
0.57
2.1
1.7
—
—
—
0
0
18
132
1.37
0.57
2.1
1.7
—
—
—
0
0
6
38
1.58
0.54
1.5
1.1
—
—
—
0
0
93
826
1.13
0.54
10.6
7.9
25.39
24.34
mmol/l
1.71
87
792
6
39
1.54
0.53
1.5
1.2
—
—
—
0
0
34
278
1.23
0.51
1.5
1.6
—
—
—
0
0
68
595
1.15
0.50
1.5
1.4
—
—
—
0
0
17
127
1.34
0.49
2.1
1.7
—
—
—
0
0
7
46
1.52
0.48
1.0
1.3
—
—
—
0
0
7
47
1.49
0.47
4.1
3.5
5.21
4.97
kpa
—
7
47
7
47
1.49
0.47
4.1
3.5
9.51
10.13
kpa
—
7
47
32
264
1.22
0.46
3.5
3.2
1.37
1.59
mmol/l
1.36
32
256
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
11
77
1.43
0.45
1.0
1.1
—
—
—
0
0
57
497
1.15
0.45
1.8
1.6
0.03
0.24
iu/ml
0.89
14
93
5
31
1.61
0.43
5.0
8.1
11.10
11.19
%
—
5
31
19
149
1.28
0.42
1.8
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
18.56
—
0
9
15
114
1.32
0.40
10.3
10.8
31.43
14841.23
u/ml
—
7
43
30
250
1.20
0.40
3.1
2.6
640.00
1457.39
titre
—
5
23
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
50
437
1.15
0.39
1.6
1.7
8.58
15.43
u/ml
1.42
15
135
7
102
0.68
0.39
1.4
1.4
220.71
318.96
u/l
—
7
97
26
214
1.22
0.39
3.7
3.3
7.65
7.59
mmol/l
0.04
26
207
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
17
133
1.28
0.38
3.4
4.0
—
—
—
0
0
12
89
1.35
0.38
1.5
1.2
—
—
—
0
0
10
72
1.39
0.37
1.6
1.2
—
—
—
0
0
6
42
1.43
0.35
12.3
7.0
5.48
5.33
kpa
—
6
42
37
320
1.16
0.35
1.4
1.6
16161.59
16552.28
e6/l
0.02
27
235
21
172
1.22
0.34
1.0
1.1
—
—
—
0
0
6
45
1.33
0.33
2.3
3.1
—
—
—
0
0
26
220
1.19
0.32
5.2
2.9
17.19
29.94
mg/l
1.46
21
153
19
157
1.21
0.29
1.3
1.3
—
—
—
0
0
8
65
1.23
0.27
2.1
1.5
—
—
—
0
0
10
77
1.30
0.26
1.6
1.2
—
—
—
0
0
10
77
1.30
0.26
1.6
1.2
—
—
—
0
0
10
77
1.30
0.26
1.6
1.2
—
—
—
0
0
6
83
0.72
0.24
1.2
1.3
20.83
10.22
u/l
—
6
78
5
38
1.32
0.23
1.4
1.3
—
—
—
0
0
5
42
1.19
0.21
1.8
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
41.52
—
0
5
11
89
1.24
0.21
1.3
1.2
—
—
—
0
0
6
50
1.20
0.19
2.2
1.1
—
—
—
0
0
123
1287
0.95
0.19
8.9
6.3
—
—
—
0
0
10
81
1.24
0.18
1.2
1.1
1576.12
1354.26
miu/ml
—
10
81
10
81
1.24
0.18
1.6
1.2
—
—
—
0
0
7
59
1.19
0.18
1.3
1.7
—
—
—
0
0
7
59
1.19
0.18
1.3
1.7
—
—
—
0
0
7
63
1.11
0.17
2.0
2.0
—
254.13
—
0
15
5
70
0.71
0.16
1.4
1.1
—
—
—
0
0
12
101
1.19
0.16
5.7
4.1
—
—
—
0
0
10
119
0.84
0.15
1.1
1.4
8923.90
64975.97
e6/l
—
10
91
12
102
1.18
0.15
2.4
1.7
—
—
—
0
0
9
81
1.11
0.15
1.8
1.7
—
—
—
0
0
7
86
0.81
0.14
1.0
1.1
—
—
—
0
0
103
997
1.04
0.10
5.3
5.3
16.90
21.85
ug/l
0.16
89
836
28
261
1.07
0.10
1.6
1.3
1.80
3.97
u/ml
3.60
15
138
48
457
1.05
0.10
3.4
4.5
306.78
3084.47
u/ml
0.71
41
400
23
213
1.08
0.09
1.3
1.1
—
—
—
0
0
16
145
1.10
0.09
1.6
1.6
—
—
—
0
0
10
88
1.14
0.08
1.3
1.2
—
—
—
0
0
89
913
0.97
0.07
1.1
1.1
1.28
1.41
g/l
8.18
89
913
9
86
1.05
0.07
1.3
1.1
—
—
—
0
0
13
142
0.91
0.06
1.4
1.5
33.99
32.96
g/l
0.11
13
127
85
870
0.98
0.06
1.1
1.1
0.78
0.72
ratio
—
7
83
28
292
0.96
0.04
7.6
6.3
354.87
368.64
umol/l
0.20
23
261
11
102
1.08
0.03
1.1
1.3
—
—
—
0
0
109
1101
0.99
0.02
2.6
2.2
9.53
10.26
ug/l
0.11
98
1010
13
131
0.99
0.00
3.8
6.3
9.77
8.22
%
0.24
13
131
13
131
0.99
0.00
1.9
3.2
43.15
45.44
%
0.18
13
131
12
115
1.04
0.00
1.2
1.4
7.92
6.30
mmol/l
0.61
12
107
0
8
0.00
0.00
0.0
7.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1696.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
13.11
—
0
5
8
88
0.91
-0.00
1.9
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_TESTICHYPO and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_TESTICHYPO | 1.58 [1.3, 1.91] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 243 out of 2410 males with E4_TESTICHYPO died.
Mortality risk
Mortality risk for people of age
years, who have E4_TESTICHYPO.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.265% |
| 5 | No data | 1.557% |
| 10 | No data | 4.102% |
| 15 | No data | 7.786% |
| 20 | No data | 13.192% |
Relationships between endpoints
↥Index endpoint: E4_TESTICHYPO – Testicular hypofunction
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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