Impacted maxillary molar

K11_MAXIL_MOLAR_FAILED_ERUPT_OBSTRUCTION_TOOTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K01.16
  • Hospital discharge: ICD-10 K01.16
  • Cause of death: ICD-10 K01.16

3 out of 7 registries used, show all original rules.

3198

4. Check minimum number of events

None

3198

5. Include endpoints

None

3198

6. Filter based on genotype QC (FinnGen only)

2881

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 24311 15031 9164
Only index persons 23622 14761 8861
Unadjusted period prevalence (%)
Whole population 0.36 0.43 0.26
Only index persons 0.47 0.54 0.34
Median age at first event (years)
Whole population 25.52 25.62 25.31
Only index persons 25.68 25.74 25.59

-FinnGen-

Key figures

All Female Male
Number of individuals 2881 2203 678
Unadjusted period prevalence (%) 0.67 0.78 0.31
Median age at first event (years) 28.98 27.94 32.37

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3029
Matched controls
30290
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K01.17
ICD-10 Finland
Retained molar with obstruction in the lower jaw
8.7
307.7
905
1420
K01.16
ICD-10 Finland
Retained molar with obstruction in the upper jaw
+∞
307.7
3029
*
EBA10
NOMESCO Finland
Operative extraction of tooth
5.0
307.7
1731
6389
K05.32
ICD-10 Finland
Periodontitis NOS
3.5
234.9
1248
5062
EBA00
NOMESCO Finland
Extraction of tooth
3.3
211.9
1974
10978
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
4.7
186.6
493
1212
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.9
169.9
1971
11790
WX110
NOMESCO Finland
Infiltration anesthesia
4.9
145.4
2781
21111
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.3
107.2
1422
8406
WZA00
NOMESCO Finland
Concise certificate
3.2
93.5
413
1417
WZA90
NOMESCO Finland
Other medical or dental certificate
2.2
93.4
1129
6331
SAA01
NOMESCO Finland
Simple examination of mouth
3.3
92.0
2729
22158
WZC00
NOMESCO Finland
Treatment plan or consultation
2.1
86.6
1467
9314
WX290
NOMESCO Finland
Other blockage of nerve
2.1
70.7
2156
16430
SAA02
NOMESCO Finland
Basic examination of mouth
2.8
66.1
2718
22989
SAA03
NOMESCO Finland
Extended examination of mouth
1.9
58.6
1682
12191
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
2.8
56.5
318
1235
SDA03
NOMESCO Finland
Periodontal treatment
1.7
43.0
1434
10497
Z01.2
ICD-10 Finland
Dental examination
1.6
34.2
1794
14377
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.7
34.0
2225
18824
K05.22
ICD-10 Finland
Acute pericoronitis
1.8
32.0
544
3251
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.6
31.9
1050
7498
EC1VA, ,
NOMESCO Finland
2.5
28.2
184
763
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.5
26.1
1215
9272
ECB00
NOMESCO Finland
Suture of gingiva
2.9
25.7
125
447
K02.1
ICD-10 Finland
Caries of dentine
1.6
25.6
2144
18458
D82
ICPC
Teeth/gum disease
1.5
25.2
1504
12050
K02.0
ICD-10 Finland
Caries limited to enamel
1.5
23.5
1053
7925
K10.3
ICD-10 Finland
Alveolitis of jaws
2.0
21.9
237
1213
K03.64
ICD-10 Finland
Dental calculus supragingival
1.5
21.8
1366
10933
KMAK, ,
NOMESCO Finland
1.4
21.6
1564
12857
SCA01
NOMESCO Finland
Preventive oral health care, short
1.4
21.3
1410
11385
K01.0
ICD-10 Finland
Embedded teeth
2.3
21.2
160
709
K00.7
ICD-10 Finland
Teething syndrome
1.8
21.1
383
2313
D19
ICPC
Teeth/gum symptom/complaint
1.5
21.1
1150
8949
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.6
19.9
506
3339
EB1HA, ,
SPAT
2.6
19.1
109
424
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.4
17.9
1150
9148
Z20.9
ICD-10 Finland
Contact with and exposure to unspecified communicable disease
2.2
17.8
147
677
EFA50
NOMESCO Finland
Excision of cyst of jaws
5.4
17.8
35
66
SPAT1324
SPAT
Screening procedure
1.6
17.3
465
3100
SFA20
NOMESCO Finland
Two-surface restoration
1.4
17.1
1809
15606
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
2.8
16.7
85
312
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
16.7
1590
13456
K09.03
ICD-10 Finland
Cyst eruption
7.3
16.5
24
33
SFA10
NOMESCO Finland
One-surface restoration
1.4
16.2
1880
16393
SXC05
NOMESCO Finland
Other oral or dental procedure
1.7
15.5
322
2013
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.5
15.3
571
4081
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
14.6
186
1007
Z29.8
ICD-10 Finland
Other specified prophylactic measures
2.1
14.2
130
624
ECB15
NOMESCO Finland
Plastic repair of oronasal or oroantral fistula
10.5
13.7
26
25
EB4VA, ,
NOMESCO Finland
1.4
13.6
620
4596
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
13.5
1411
11959
N02BE01
ATC
paracetamol; systemic, rectal
1.4
13.4
2405
22119
K05.30
ICD-10 Finland
Periodontitis complex
1.7
13.3
243
1466
K07.60
ICD-10 Finland
Snapping jaw
1.7
13.0
227
1352
Z50.1
ICD-10 Finland
Other physical therapy
2.4
13.0
84
349
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
2.5
12.4
77
314
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
1.6
12.3
326
2157
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.4
11.9
683
5259
K07.24
ICD-10 Finland
Open bite
2.4
11.8
79
334
SMAK, ,
NOMESCO Finland
3.9
11.6
34
89
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.4
11.6
657
5043
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.4
11.3
509
3752
K03.00
ICD-10 Finland
Approximal wear
1.6
11.0
242
1531
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
2.7
11.0
56
207
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
10.9
2707
25677
LANKA, ,
NOMESCO Finland
28.1
10.7
14
5
EBA10, ,
SPAT
2.6
10.2
56
215
VALMI, ,
NOMESCO Finland
1.3
10.1
949
7834
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
1.9
10.0
133
730
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
1.7
10.0
199
1229
-1, ,
NOMESCO Finland
1.3
9.7
1301
11222
Z26.9
ICD-10 Finland
Need for immunization against unspecified infectious disease
2.1
9.6
93
459
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
9.6
478
3583
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.5
9.3
299
2063
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.4
9.2
582
4526
127
Kela drug reimbursment
Transplant complication
2.9
9.1
42
148
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.4
8.7
497
3804
SXA20
NOMESCO Finland
Local application of medicine to mouth
1.5
8.7
270
1851
KAY60, ,
NOMESCO Finland
1.7
8.6
151
902
SBB10
NOMESCO Finland
Dental impressions
1.4
8.3
359
2623
L04AA06
ATC
mycophenolic acid; systemic
2.6
8.2
47
185
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
3.1
8.1
32
103
SPAT1312
SPAT
General health counselling
1.3
8.1
1180
10217
Z94.0
ICD-10 Finland
Kidney transplant status
3.2
7.9
30
94
K03.30
ICD-10 Finland
Internal granuloma of pulp
4.3
7.9
20
47
HMAK, ,
NOMESCO Finland
1.4
7.8
319
2308
D31
ICPC
Digestive, Medical examin/health eval partial
5.9
7.7
20
34
K07.38
ICD-10 Finland
Other anomaly in the position of the teeth
1.7
7.6
139
842
SAA04
NOMESCO Finland
Special examination of mouth
1.5
7.5
201
1333
K05.18
ICD-10 Finland
Chronic gingivitis
1.5
7.5
257
1796
WX740
NOMESCO Finland
Nitrogen oxide therapy
2.6
7.4
41
159
WYA50
NOMESCO Finland
Student oral health check consistent with decree to assess need for oral health guidance and services
1.3
7.3
640
5199
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.4
7.3
273
1942
WZC00, ,
SPAT
1.3
7.2
519
4103
SPAT1193
SPAT
Pap smear
1.4
7.2
399
3036
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
3.6
7.1
23
65
K07.13
ICD-10 Finland
Retrognaty, mandibular
2.1
7.1
64
308
SCA02
NOMESCO Finland
Preventive oral health care
1.3
6.9
514
4081
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.4
6.9
296
2157
SJC10
NOMESCO Finland
Orthodontic band in one tooth
1.7
6.9
121
726
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.4
6.7
367
2786
IHA10, ,
SPAT
1.8
6.6
99
567
K01.1
ICD-10 Finland
Impacted teeth
2.1
6.5
58
279
OAB39, ,
SPAT
1.3
6.5
533
4290
L04AD02
ATC
tacrolimus; systemic
2.7
6.2
32
120
Z30.4
ICD-10 Finland
Surveillance of contraceptive drugs
1.3
6.2
631
5209
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.3
6.2
540
4379
WYA10
NOMESCO Finland
Emergency care or similar visit
1.4
6.1
240
1721
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.7
6.1
31
116
Z2221
NOMESCO Finland
Medical doctor
0.8
6.1
402
5080
F45.8
ICD-10 Finland
Other somatoform disorders
1.4
6.1
286
2119
G47.8
ICD-10 Finland
Other sleep disorders
1.7
6.1
102
605
WZB00, ,
SPAT
1.3
6.0
651
5412
EBA12, ,
SPAT
3.5
6.0
20
58

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
106
317
3.43
29.44
3.7
2.8
—
—
—
0
0
269
1407
2.00
23.37
3.0
2.3
0.39
0.16
e6/l
0.69
263
1323
1018
7921
1.43
17.91
3.6
3.3
0.01
0.00
estimate
0.19
430
3145
1372
11295
1.39
17.23
3.6
3.1
0.03
0.03
estimate
0.12
383
2762
190
1002
1.96
16.07
3.8
2.5
1.02
1.02
ratio
0.14
174
867
559
4076
1.46
13.37
3.3
2.5
542.77
557.10
mosm/kgh2o
0.74
510
3574
1384
11718
1.33
13.22
9.3
9.1
0.00
0.00
e9/l
0.33
1209
9634
1090
8921
1.35
13.05
3.1
2.7
0.03
0.05
estimate
0.44
376
2748
292
1925
1.57
11.22
5.7
5.1
0.03
0.09
%
0.64
60
378
1659
14658
1.29
10.61
3.9
3.3
0.00
0.00
estimate
1.34
456
3264
282
1877
1.55
10.38
5.8
4.9
0.08
0.10
%
0.10
59
403
1668
14802
1.28
10.06
4.0
3.3
0.00
5.50
estimate
3.22
453
3233
287
1943
1.53
9.78
5.8
4.8
0.59
0.79
%
0.70
64
469
1668
14835
1.28
9.73
4.0
3.4
0.00
0.01
estimate
1.97
457
3190
92
453
2.06
9.54
2.4
3.0
22.45
25.13
mg/l
0.29
64
288
35
108
3.27
9.44
2.7
2.3
1.19
1.19
mmol/l
0.04
35
108
35
112
3.15
8.91
2.7
2.2
3.88
3.91
mmol/l
0.16
35
112
35
112
3.15
8.91
2.7
2.2
106.20
105.92
mmol/l
0.16
35
112
844
6961
1.29
8.78
3.6
2.9
29.71
63.21
e6/l
1.80
688
5041
269
1863
1.49
8.22
5.2
4.6
0.51
0.53
%
0.05
65
442
850
7072
1.28
8.15
4.8
4.1
—
—
—
0
0
579
4664
1.30
7.01
2.8
2.5
7.92
9.64
e6/l
1.13
531
4169
317
2355
1.39
6.62
2.0
1.9
0.03
0.03
estimate
0.12
116
633
2289
21629
1.24
5.87
4.6
4.4
14.37
14.31
pmol/l
0.67
2155
20025
215
1531
1.44
5.73
6.8
4.6
1.33
1.36
mmol/l
0.05
186
1299
192
1341
1.46
5.68
4.9
4.1
4.72
4.78
kpa
0.16
187
1306
1045
9210
1.21
5.44
4.2
3.5
72.29
67.80
e6/l
0.06
767
5633
2485
23751
1.26
5.44
13.5
12.7
13.12
13.14
%
0.38
2460
23437
218
1585
1.40
5.20
6.8
4.5
5.73
5.82
kpa
0.79
213
1543
217
1583
1.40
5.08
6.8
4.5
7.38
7.37
ph
1.47
158
901
803
6981
1.20
4.71
3.5
3.1
1.02
1.71
kg/l
1.08
515
4417
22
81
2.73
4.51
4.5
4.2
—
—
—
0
0
237
1799
1.34
4.37
1.3
1.2
—
—
—
0
0
2531
24387
1.23
4.26
5.4
5.1
1.69
1.73
mu/l
0.94
2454
23390
702
6079
1.20
4.25
3.5
2.8
0.24
0.26
e6/l
0.11
542
4231
779
6822
1.19
4.15
2.7
2.5
56.83
57.09
u/l
0.04
740
6324
325
2602
1.28
4.07
3.1
3.1
575.04
604.15
ng/l
0.06
252
1946
25
106
2.37
3.90
35.7
28.7
120.47
132.76
ug/l
0.26
19
86
173
1279
1.37
3.81
3.0
3.2
1.23
1.22
mmol/l
0.46
157
1082
1201
10975
1.16
3.67
2.4
2.1
—
—
—
0
0
1375
12692
1.15
3.65
2.9
2.8
—
—
estimate
—
0
0
268
3344
0.78
3.61
2.1
2.1
—
—
—
0
0
405
3375
1.23
3.59
2.9
2.2
15.36
15.16
umol/l
0.19
383
3136
9
17
5.31
3.51
8.3
4.9
4.91
6.84
mmol/l
—
9
17
1288
11880
1.15
3.37
3.6
3.0
6.37
6.30
ph
1.65
795
6636
44
246
1.80
3.36
4.5
2.9
0.82
1.20
%
0.91
39
222
1196
10985
1.15
3.31
2.7
2.4
71.38
69.16
nmol/l
2.48
1152
10418
17
65
2.62
3.30
2.7
2.0
—
—
—
0
0
405
3410
1.22
3.25
3.5
2.6
4.90
4.38
e6/l
0.32
250
1508
60
371
1.63
3.21
1.3
1.1
—
—
—
0
0
71
462
1.55
3.09
4.5
3.5
3.77
3.95
e9/l
0.32
71
462
2800
27442
1.27
3.02
10.3
9.2
—
—
—
0
0
146
1097
1.35
2.97
6.6
4.1
81.25
69.19
ng/l
0.96
131
998
18
75
2.41
2.96
1.3
1.2
—
—
—
0
0
52
320
1.64
2.87
4.0
3.4
8.13
6.67
pmol/l
0.31
52
320
109
788
1.40
2.82
3.4
3.4
1.14
1.39
%
1.82
109
783
15
59
2.55
2.78
3.1
3.1
0.57
0.61
mmol/l
2.48
15
59
245
1996
1.25
2.72
1.5
1.5
7.52
8.20
u/l
0.69
206
1613
22
105
2.10
2.68
3.0
1.6
—
—
—
0
0
37
212
1.75
2.67
2.6
2.5
77.76
75.02
%
0.45
37
205
2379
23032
1.15
2.66
3.5
3.3
4.56
4.59
mmol/l
1.08
2319
22165
28
147
1.91
2.65
1.3
1.3
70.96
70.54
umol/l
0.04
28
147
145
1110
1.32
2.63
1.6
1.6
44.63
41.17
nmol/l
0.43
145
1097
776
7016
1.14
2.60
7.4
5.8
1.09
1.07
inr
1.03
674
5867
154
1193
1.31
2.57
1.7
1.7
—
—
—
0
0
1532
14449
1.12
2.57
8.9
8.4
3.90
4.01
e9/l
1.51
1400
12654
2367
22926
1.15
2.56
3.4
3.2
1.47
1.45
mmol/l
1.53
2300
21984
356
4155
0.84
2.55
2.2
2.1
—
—
—
0
0
104
763
1.38
2.50
1.8
2.4
4.94
6.55
ug/l
0.75
95
662
31
172
1.81
2.50
1.2
1.3
182.33
170.64
pmol/l
0.15
31
172
296
2484
1.21
2.49
1.4
1.4
11.92
13.69
iu/l
0.81
253
2045
2672
26135
1.19
2.48
11.9
10.4
18.78
19.87
mg/l
1.10
2145
20675
1379
12947
1.12
2.47
7.3
6.2
0.52
0.53
e9/l
0.88
1259
11440
313
2646
1.20
2.45
2.2
2.0
386.33
396.54
nmol/l
0.41
292
2456
1379
12952
1.12
2.45
7.3
6.3
0.04
0.04
e9/l
0.69
1255
11436
258
2140
1.22
2.45
2.1
2.0
9.81
10.21
nmol/l
0.28
245
1969
82
580
1.43
2.44
1.5
1.6
6.17
6.48
mmol/l
0.82
75
537
2198
21207
1.13
2.44
3.1
2.9
1.10
1.15
mmol/l
4.08
2135
20292
360
3087
1.19
2.41
3.0
2.2
2.50
2.52
g/l
0.33
341
2830
10
33
3.04
2.35
1.4
1.4
8.14
5.52
pmol/l
—
5
10
11
39
2.83
2.34
1.2
2.0
11.81
11.28
mmol/l
0.07
11
39
35
206
1.71
2.33
2.7
2.4
9.31
11.69
%
1.33
35
201
241
2002
1.22
2.27
1.2
1.1
280.56
146.19
titre
—
9
58
57
382
1.50
2.26
1.8
1.8
0.76
2.26
ug/l
1.04
51
338
166
2064
0.79
2.24
2.7
2.7
32.29
32.48
%
0.09
136
1590
338
2912
1.18
2.16
1.7
1.6
—
—
—
0
0
1428
13503
1.11
2.14
7.3
6.2
2.02
2.04
e9/l
0.38
1329
12203
246
2919
0.83
2.13
2.6
2.8
410.91
421.75
ng/l
0.02
108
1279
316
2712
1.18
2.12
3.2
2.3
24.85
24.35
%
0.28
302
2502
2376
23102
1.13
2.11
3.5
3.4
2.72
2.75
mmol/l
0.95
2300
22135
60
413
1.46
2.10
2.5
2.3
—
—
—
0
0
2255
21863
1.12
2.08
3.3
3.1
5.43
5.46
mmol/l
0.41
2163
20639
304
2606
1.19
2.07
3.2
3.2
—
—
—
0
0
2947
29183
1.36
2.07
17.9
16.0
6.71
6.86
e9/l
4.29
2909
28643
41
262
1.57
2.03
2.8
2.8
1320.15
1428.97
e6/l
0.39
34
218
2945
29164
1.35
2.03
17.8
15.9
29.87
29.85
pg
0.33
2934
28948
2945
29166
1.35
2.01
18.1
16.2
41.88
41.00
%
0.24
2929
28935
21
111
1.90
2.00
1.5
1.7
38.25
41.91
%
0.16
12
81
2945
29167
1.35
2.00
17.9
16.0
4.56
4.57
e12/l
0.07
2908
28655
2944
29160
1.34
1.95
17.8
15.9
89.18
89.13
fl
0.28
2933
28944
81
598
1.36
1.95
4.6
3.3
53.55
56.97
%
1.73
81
598
1414
13410
1.10
1.94
7.5
6.5
0.18
0.18
e9/l
0.11
1312
11982
10
39
2.57
1.94
1.9
1.3
—
—
—
0
0
486
4343
1.14
1.93
2.6
2.4
312.17
311.47
umol/l
0.06
459
4011
2945
29177
1.34
1.89
18.0
16.1
135.65
135.54
g/l
0.20
2932
28963
317
2754
1.17
1.86
1.5
1.5
—
—
—
0
0
2942
29148
1.32
1.84
17.9
16.0
264.03
264.18
e9/l
0.05
2909
28661
974
9095
1.10
1.80
1.5
1.4
1.10
1.62
u/ml
1.88
366
2575
865
8031
1.11
1.79
5.5
4.7
38.02
37.69
g/l
1.08
834
7540
8
29
2.76
1.79
3.4
2.5
18.40
17.92
mmol/l
—
8
24
938
8745
1.11
1.79
1.9
1.8
—
—
—
0
0
437
3900
1.14
1.78
1.5
1.4
412.05
533.69
titre
0.93
83
751
181
2168
0.82
1.77
2.4
2.4
31.95
55.00
u/l
0.51
164
1806
60
430
1.40
1.75
2.5
2.2
132.25
133.57
g/l
0.26
55
368
85
645
1.33
1.74
1.6
1.8
163.46
181.26
pmol/l
0.59
80
615
746
6882
1.11
1.74
5.7
5.5
—
—
—
0
0
83
628
1.33
1.73
3.7
5.5
—
—
—
0
0
648
5934
1.12
1.73
2.8
2.5
18.16
96.80
ng/l
0.86
248
2215
418
3728
1.14
1.72
1.5
1.6
88859855.99
28663226.99
pmol/l
0.82
377
3283
319
2792
1.16
1.71
1.9
1.8
—
—
—
0
0
21
118
1.79
1.70
1.8
1.3
9331.86
26751.90
e6/l
0.93
14
79
423
3779
1.14
1.70
5.2
4.7
12.99
14.60
mg/mmol
0.25
319
2648
2430
23749
1.12
1.67
10.9
9.4
3.88
3.88
mmol/l
0.19
2373
22998
100
782
1.29
1.66
7.9
10.8
0.73
0.66
%
1.11
100
775
23
134
1.72
1.66
2.6
2.4
0.29
0.21
e9/l
0.18
11
64
688
6342
1.11
1.62
1.9
1.7
—
—
—
0
0
101
795
1.28
1.60
7.7
10.6
1.43
1.32
%
0.41
101
787
568
5186
1.12
1.60
3.0
2.7
100.34
103.75
ug/g
0.12
464
4072
43
295
1.46
1.60
1.2
1.0
—
—
—
0
0
2426
23725
1.11
1.59
10.8
9.3
139.40
139.44
mmol/l
0.39
2377
23047
93
727
1.29
1.57
1.4
1.4
14.13
12.18
u/l
0.38
85
636
99
781
1.28
1.55
1.2
1.1
—
—
—
0
0
23
137
1.68
1.55
2.1
1.7
0.90
0.81
%
—
9
69
1905
18432
1.09
1.53
4.6
4.0
—
39.22
—
0
14
45
315
1.44
1.52
2.1
1.7
19716.00
15805.58
e6/l
0.12
30
238
412
3705
1.13
1.51
4.1
4.0
72.31
90.42
mg/l
0.66
302
2648
1846
17844
1.09
1.50
4.4
4.1
2966.42
1326.82
e6/l
0.46
40
203
209
1792
1.18
1.48
1.2
1.2
—
—
—
0
0
7
28
2.50
1.45
5.3
2.7
—
—
—
0
0
25
156
1.61
1.43
1.8
1.7
45.81
44.62
%
0.05
16
115
1239
11797
1.09
1.43
1.9
1.9
—
—
—
0
0
1354
12940
1.08
1.43
4.8
4.4
5.99
6.06
mmol/l
0.63
1235
11397
1705
16450
1.08
1.41
7.2
6.5
69.07
71.58
u/l
3.45
1633
15566
682
6328
1.10
1.41
2.6
2.6
2.34
2.35
mmol/l
1.24
642
5871
910
8565
1.09
1.38
3.1
2.6
0.11
0.08
0.13
27
75
1765
17066
1.08
1.36
3.5
3.3
62.28
60.51
ug/l
0.29
1713
16268
141
1178
1.21
1.35
2.2
2.4
0.59
0.66
ug/l
0.73
67
539
795
7445
1.09
1.35
2.7
2.2
—
—
—
0
0
78
989
0.78
1.34
1.1
1.1
—
—
—
0
0
2704
26662
1.13
1.34
9.2
8.4
24.82
25.37
u/l
0.53
2659
25998
16
272
0.59
1.33
17.3
19.2
78709.44
782.87
nmol/l
0.48
16
265
398
3604
1.12
1.32
3.4
2.5
0.94
1.18
e6/l
0.48
248
1711
75
586
1.29
1.31
1.4
1.3
—
—
—
0
0
2475
24294
1.10
1.30
13.5
12.6
333.79
333.81
g/l
0.03
2463
24126
313
2796
1.13
1.30
5.8
4.0
0.84
0.83
mmol/l
0.49
302
2660
19
305
0.62
1.27
1.6
1.7
—
—
—
0
0
259
2289
1.14
1.27
1.5
1.4
—
—
—
0
0
520
4792
1.10
1.25
1.4
1.3
25.79
20.08
iu/ml
0.43
127
1202
229
2010
1.15
1.24
4.0
3.4
1.34
1.40
ug/l
0.19
212
1839
70
547
1.29
1.24
1.3
1.3
4.74
4.37
u/ml
0.08
35
258
40
288
1.39
1.21
1.5
1.4
3.25
2.92
g/l
0.50
32
200
40
288
1.39
1.21
1.5
1.4
6.82
6.30
g/l
0.48
32
201
40
288
1.39
1.21
1.5
1.4
0.44
0.36
g/l
0.85
32
199
9
168
0.53
1.18
1.0
2.5
109.89
151.90
nmol/l
—
9
153
526
4865
1.10
1.17
2.7
2.5
6680.18
7340.23
u/l
0.18
226
1969
142
1207
1.19
1.17
6.9
9.4
97.54
96.31
%
3.48
137
1163
293
2627
1.13
1.17
2.8
2.5
29.10
29.09
s
0.01
280
2554
26
174
1.50
1.15
1.4
1.6
1.24
2.83
nmol/l
0.67
21
134
1238
11866
1.07
1.15
7.3
6.3
0.64
0.65
%
0.59
1180
11178
1312
12603
1.07
1.14
7.2
6.1
30.89
30.53
%
0.71
1268
12059
29
199
1.46
1.14
1.0
1.1
123.62
115.18
pmol/l
0.29
29
199
1291
12396
1.07
1.13
7.0
6.0
55.44
55.75
%
0.52
1262
11932
355
3226
1.11
1.13
1.3
1.3
101.08
144.92
u/ml
1.45
141
1185
275
3063
0.89
1.12
2.9
2.8
—
—
—
0
0
138
1178
1.18
1.09
2.9
2.2
6.65
7.10
iu/ml
0.06
47
298
933
8871
1.07
1.07
8.0
5.7
1.21
1.21
mmol/l
0.48
835
7697
136
1163
1.18
1.06
1.3
1.3
0.28
1.39
u/ml
—
10
57
811
7675
1.08
1.06
1.5
1.4
2.04
2.01
g/l
0.24
596
5078
55
427
1.29
1.05
3.3
3.1
—
—
—
0
0
7
33
2.12
1.05
2.7
1.9
—
—
—
0
0
274
3032
0.89
1.01
1.2
1.2
—
—
—
0
0
872
8287
1.07
1.01
1.6
1.7
1.22
1.29
mmol/l
2.15
797
7458
22
322
0.68
1.01
2.7
2.0
—
—
—
0
0
21
310
0.68
1.01
1.2
1.5
1.10
1.26
promille
0.28
16
228
678
6386
1.08
1.00
3.7
3.6
8.67
8.75
mmol/l
0.12
630
5777
15
91
1.65
1.00
1.5
1.2
—
—
—
0
0
580
6186
0.92
0.99
2.3
2.0
—
—
—
0
0
19
123
1.55
0.99
1.7
1.8
0.58
2.25
u/field
3.35
12
83
13
76
1.71
0.98
1.0
1.1
—
—
—
0
0
1185
11390
1.07
0.98
2.0
1.9
—
—
—
0
0
5
23
2.18
0.98
1.6
2.2
—
—
—
0
0
554
5182
1.08
0.98
1.6
1.5
19.16
19.45
nmol/l
0.23
508
4640
0
29
0.00
0.97
0.0
1.1
—
67.86
—
0
14
14
84
1.67
0.97
2.5
2.4
35.21
27.31
%
1.11
14
84
0
31
0.00
0.96
0.0
1.0
—
0.17
—
0
16
193
1711
1.14
0.95
1.4
1.3
3.58
3.85
ug/l
0.42
188
1636
1081
10368
1.07
0.95
5.2
5.1
9.24
10.01
umol/l
2.84
1014
9681
32
233
1.38
0.95
1.5
1.6
21.06
23.99
umol/l
0.27
32
216
13
77
1.69
0.95
1.0
1.0
—
—
—
0
0
13
77
1.69
0.95
1.3
1.4
—
—
—
0
0
42
320
1.32
0.94
1.0
1.0
—
—
—
0
0
23
328
0.70
0.93
1.2
1.2
—
—
—
0
0
519
4854
1.08
0.92
2.1
2.2
226.42
208.08
u/l
0.11
503
4638
31
226
1.38
0.92
3.6
2.8
160.30
206.95
e6/l
1.02
23
183
242
2183
1.12
0.91
11.2
6.4
1.10
1.07
mmol/l
1.17
226
2032
23
159
1.45
0.91
6.1
2.9
—
—
—
0
0
70
851
0.82
0.91
2.0
1.9
—
—
—
0
0
94
792
1.19
0.90
8.3
10.7
95.65
94.21
%
4.10
94
786
25
176
1.42
0.90
1.0
1.1
—
—
—
0
0
6
29
2.07
0.89
6.3
7.4
—
—
—
0
0
70
574
1.22
0.89
1.2
1.1
—
—
—
0
0
131
1138
1.16
0.88
1.8
1.6
0.46
0.44
nmol/l
0.08
114
939
260
2361
1.11
0.88
1.4
1.3
133.76
283.47
u/ml
2.84
243
2186
18
119
1.52
0.88
2.1
1.4
—
—
—
0
0
13
79
1.65
0.88
2.4
1.6
—
—
—
0
0
158
1394
1.14
0.86
1.4
1.4
—
—
—
0
0
1232
11897
1.06
0.86
7.3
6.2
2.71
2.68
%
0.19
1177
11224
113
973
1.17
0.86
2.5
2.3
3.63
3.64
iu/l
0.00
52
455
79
660
1.20
0.84
1.3
1.3
38.36
40.86
u/ml
—
5
51
16
104
1.54
0.84
1.2
1.4
176.69
185.01
u/l
0.39
16
104
6
31
1.94
0.84
3.3
1.2
—
—
—
0
0
146
1654
0.88
0.83
1.1
1.1
—
—
—
0
0
6
114
0.53
0.82
1.2
1.1
—
—
—
0
0
59
480
1.23
0.82
1.8
1.6
0.62
0.61
g/l
0.05
47
376
1233
11920
1.06
0.82
7.3
6.3
8.14
8.16
%
0.13
1183
11270
37
284
1.31
0.81
1.5
1.4
—
—
—
0
0
312
3384
0.91
0.81
1.5
1.5
—
—
—
0
0
102
1184
0.86
0.81
1.1
1.1
1.27
2.64
u/ml
2.40
57
648
13
81
1.61
0.81
1.0
1.2
—
—
—
0
0
237
2154
1.11
0.80
1.3
1.3
—
—
—
0
0
11
66
1.67
0.78
1.8
3.2
7.72
7.35
mmol/l
0.08
11
66
5
98
0.51
0.78
1.0
1.0
—
—
—
0
0
154
1371
1.13
0.76
6.6
8.7
-0.46
0.26
mmol/l
1.36
113
1046
23
166
1.39
0.75
1.3
1.1
—
—
—
0
0
287
2644
1.09
0.75
1.4
1.3
234.23
230.95
miu/ml
0.05
140
1334
155
1733
0.89
0.74
1.7
1.7
0.21
0.22
mg/l
0.09
58
717
9
55
1.64
0.73
1.1
1.2
—
—
—
0
0
12
76
1.58
0.71
2.9
1.3
—
—
—
0
0
29
220
1.32
0.71
2.9
2.7
513.76
540.28
e6/l
0.12
21
172
57
686
0.83
0.71
2.8
2.8
227.52
92.01
ng/l
1.00
52
582
21
151
1.39
0.71
1.9
2.4
—
—
—
0
0
5
26
1.92
0.70
2.0
1.7
40.54
45.23
g/l
—
5
26
9
142
0.63
0.69
1.1
1.1
—
—
—
0
0
323
3006
1.08
0.68
1.7
1.6
315.11
311.51
mu/l
0.07
300
2685
2670
26453
1.08
0.68
12.2
10.5
69.30
67.88
umol/l
2.07
2658
26101
37
293
1.27
0.68
1.3
1.3
85.76
66.58
ug/l
0.77
37
293
31
240
1.29
0.67
1.5
1.5
—
—
—
0
0
7
121
0.58
0.67
1.4
2.2
—
—
—
0
0
35
276
1.27
0.66
1.0
1.0
—
—
—
0
0
5
95
0.53
0.66
1.0
1.0
4.61
5.17
mg/g
—
5
95
5
28
1.79
0.66
1.0
1.7
—
—
—
0
0
685
6555
1.06
0.65
2.2
2.1
2.54
2.48
mg/l
0.38
598
5670
225
2445
0.91
0.64
3.1
2.7
5.18
6.31
umol/l
1.13
194
2040
324
3467
0.93
0.64
1.5
1.5
1.12
1.15
ratio
0.26
213
2082
13
189
0.69
0.63
1.2
1.2
—
—
—
0
0
325
3039
1.08
0.62
3.6
2.6
4.26
4.64
e9/l
0.87
297
2726
21
280
0.75
0.62
22.7
25.9
1317.52
1373.25
nmol/l
0.15
21
272
88
768
1.15
0.61
1.3
1.3
3.44
4.32
u/ml
—
5
76
16
113
1.42
0.61
1.3
1.9
—
115.74
—
0
19
139
1251
1.12
0.61
1.7
2.1
21.22
29.59
u/ml
1.82
130
1208
283
2636
1.08
0.61
1.2
1.2
—
—
—
0
0
80
919
0.87
0.60
1.1
1.1
—
—
—
0
0
87
760
1.15
0.60
1.3
1.3
12.04
17.78
u/ml
—
7
112
0
21
0.00
0.60
0.0
1.4
—
1.40
—
0
9
80
917
0.87
0.59
1.1
1.1
—
—
—
0
0
19
140
1.36
0.58
1.8
1.6
—
—
—
0
0
123
1367
0.90
0.57
1.2
1.1
3.81
2.79
u/ml
0.40
70
739
170
1555
1.10
0.56
2.2
1.8
1.30
1.31
g/l
0.01
165
1452
120
1078
1.12
0.56
3.1
2.6
20.32
20.44
s
0.13
101
913
14
99
1.42
0.54
1.6
1.4
27.14
28.20
s
0.49
14
99
29
231
1.26
0.53
1.2
1.3
1.74
1.77
mmol/l
0.12
29
214
35
286
1.23
0.52
2.6
1.5
—
—
—
0
0
35
286
1.23
0.52
2.6
1.5
—
—
—
0
0
35
286
1.23
0.52
2.6
1.5
—
—
—
0
0
35
286
1.23
0.52
2.6
1.5
—
—
—
0
0
9
63
1.43
0.52
1.1
1.3
—
—
—
0
0
153
1400
1.10
0.51
6.6
8.7
7.41
7.41
ph
0.11
94
745
6
40
1.50
0.51
2.5
2.4
1.22
1.26
umol/l
—
6
30
490
5126
0.95
0.51
4.6
3.8
96.32
95.41
%
0.43
474
4988
75
851
0.88
0.50
1.1
1.1
0.03
0.27
u/ml
4.15
22
263
35
288
1.22
0.50
1.0
1.1
—
—
—
0
0
7
108
0.65
0.48
6.9
3.1
0.29
0.75
index
—
7
108
2052
20250
1.04
0.48
4.1
3.7
35.65
35.82
mmol/mol
0.45
1987
19445
469
4486
1.05
0.48
1.4
1.5
—
—
—
0
0
460
4398
1.05
0.48
1.3
1.3
7.26
8.29
u/ml
0.16
220
1797
154
1417
1.09
0.47
10.6
8.9
—
—
—
0
0
20
255
0.78
0.46
1.6
1.3
4.17
2.48
u/ml
0.33
11
131
1199
11718
1.04
0.46
2.0
1.9
—
—
—
0
0
28
227
1.24
0.46
1.4
1.3
—
—
—
0
0
19
243
0.78
0.45
2.7
2.0
—
—
—
0
0
122
1113
1.10
0.45
3.5
3.1
68.31
70.83
e9/l
0.37
87
769
288
2722
1.06
0.45
1.5
1.6
60.88
59.90
ug/l
0.16
288
2722
23
183
1.26
0.44
1.4
1.3
—
—
—
0
0
44
512
0.86
0.43
2.5
2.5
1.78
1.93
index
0.08
18
282
136
1251
1.09
0.43
1.9
1.8
0.05
0.51
estimate
0.47
66
521
239
2249
1.07
0.43
2.1
2.2
6.18
6.28
ph
1.09
152
1419
11
151
0.73
0.42
1.3
1.1
1.93
5.47
u/ml
—
6
103
16
207
0.77
0.42
1.3
1.2
5.44
7.49
mm/h
1.02
16
207
34
285
1.20
0.42
1.3
1.3
—
—
—
0
0
288
2729
1.06
0.42
1.4
1.4
—
—
—
0
0
98
1079
0.91
0.42
1.1
1.1
4.49
4.58
eliau/ml
0.02
17
161
60
680
0.88
0.42
1.8
1.6
492.21
5853.70
e6/l
0.47
53
527
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
1.03
—
0
16
217
2040
1.07
0.41
3.4
3.6
4.77
4.71
pmol/l
0.43
206
1858
32
268
1.20
0.40
2.3
2.7
35.78
92.44
ug/min
1.34
25
181
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
26.17
—
0
6
0
17
0.00
0.40
0.0
1.7
—
271.47
—
0
17
153
1421
1.08
0.40
1.6
1.7
—
—
—
0
0
17
132
1.29
0.40
1.2
1.3
162.76
83.00
nmol/24h
0.35
17
132
30
357
0.84
0.39
1.1
1.1
28.95
36.98
mg/l
1.15
24
289
0
19
0.00
0.39
0.0
1.0
—
16.21
—
0
7
177
1656
1.07
0.39
4.3
3.1
1.57
1.65
%
0.61
168
1481
96
1051
0.91
0.38
1.5
1.3
193.31
220.74
u/ml
0.67
69
640
5
36
1.39
0.38
1.6
1.1
0.02
0.03
u/ml
—
5
36
569
5505
1.04
0.38
2.0
1.9
0.91
1.03
mg/l
0.44
420
3911
670
6504
1.04
0.37
4.0
3.2
0.00
0.35
—
5
23
1890
19129
0.97
0.37
3.0
2.9
27.59
29.55
u/l
1.42
1836
18433
24
290
0.83
0.37
1.3
1.2
0.45
0.70
ratio
6.70
15
158
68
610
1.12
0.37
1.3
1.5
0.49
0.51
e9/l
0.21
68
610
105
1142
0.92
0.37
1.1
1.1
0.69
1.34
u/ml
1.14
44
535
37
318
1.17
0.36
1.8
1.3
—
9.32
—
0
8
60
671
0.89
0.36
1.8
1.6
7.57
23.40
e6/l
1.67
44
493
184
1731
1.07
0.36
2.8
2.9
—
—
—
0
0
214
2024
1.06
0.35
3.2
2.7
10.35
10.50
g/l
0.30
205
1876
6
43
1.40
0.35
1.0
1.1
—
—
—
0
0
9
126
0.71
0.35
1.8
1.3
140.56
158.82
mmol/24h
—
9
126
852
8322
1.03
0.34
1.8
1.7
97.56
97.53
pmol/l
0.01
512
4849
12
156
0.77
0.34
1.3
1.2
—
—
—
0
0
87
950
0.91
0.34
1.1
1.1
4.31
8.48
u/ml
1.46
46
462
128
1191
1.08
0.34
1.7
1.7
5.60
7.50
u/ml
0.68
49
343
31
265
1.17
0.33
2.9
4.6
10.19
63.40
u/ml
—
10
86
10
133
0.75
0.33
1.4
2.2
—
—
—
0
0
47
529
0.89
0.32
1.2
1.3
297.41
323.28
ug/g
0.26
17
237
141
1504
0.93
0.32
4.1
2.9
7.33
7.34
ph
0.13
105
1079
58
644
0.90
0.32
1.7
1.6
—
—
—
0
0
119
1277
0.93
0.32
1.1
1.1
—
—
—
0
0
63
696
0.90
0.32
3.2
2.2
1.22
1.21
g/l
0.03
57
616
29
337
0.86
0.31
1.0
1.1
13.83
14.47
u/ml
—
10
160
42
372
1.13
0.30
1.1
1.1
0.24
2.37
u/ml
—
10
143
12
151
0.79
0.28
1.0
2.3
10.33
10.21
mmol/l
0.05
12
144
30
344
0.87
0.28
1.1
1.1
212.21
200.61
mg/l
0.18
24
295
1487
14682
1.03
0.28
2.5
2.4
—
—
—
0
0
8
62
1.29
0.28
1.0
1.0
12.67
4.85
u/ml
—
8
62
8
62
1.29
0.28
1.5
1.2
40.54
36.23
g/l
—
8
54
148
1398
1.06
0.28
6.8
8.6
5.00
4.96
kpa
0.19
143
1336
148
1398
1.06
0.28
6.7
8.5
14.81
14.08
kpa
0.84
143
1339
79
729
1.09
0.27
1.4
1.4
—
—
—
0
0
110
1029
1.07
0.27
6.9
3.2
7.41
7.41
ph
0.21
99
874
42
375
1.12
0.27
1.1
1.1
1.88
2.28
u/ml
0.08
13
111
191
1820
1.05
0.27
2.2
2.3
13.95
16.89
au/ml
0.41
25
243
10
77
1.30
0.26
9.3
5.7
13.94
79.16
mg/mmol
—
10
70
503
5162
0.97
0.25
5.4
3.5
7.39
7.39
ph
0.86
358
3461
382
3933
0.97
0.24
1.2
1.2
—
—
—
0
0
467
4550
1.03
0.24
4.0
3.7
—
—
—
0
0
25
286
0.87
0.23
1.7
2.0
3.18
2.12
u/ml
—
5
101
61
661
0.92
0.23
1.2
1.5
48.24
73.43
pmol/l
0.78
55
637
13
106
1.23
0.23
1.1
1.1
—
—
—
0
0
50
546
0.91
0.22
1.1
1.1
—
—
—
0
0
158
1508
1.05
0.22
1.0
1.1
0.56
0.62
ratio
—
10
113
360
3704
0.97
0.22
1.5
1.5
59.72
61.82
ug/l
0.39
330
3211
211
2030
1.04
0.22
1.5
1.6
—
—
—
0
0
76
813
0.93
0.21
1.3
1.2
—
—
—
0
0
813
8266
0.98
0.21
2.4
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
21
182
1.15
0.21
1.1
1.1
2.33
6.02
u/ml
0.90
14
116
0
12
0.00
0.21
0.0
2.0
—
37.00
—
0
12
114
1081
1.06
0.21
7.1
4.6
23.71
24.00
mmol/l
0.54
114
1074
8
103
0.78
0.21
1.3
1.6
2.63
2.62
mg/l
—
8
98
0
13
0.00
0.21
0.0
1.0
—
0.03
—
0
7
22
251
0.88
0.20
1.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
0.00
—
0
9
9
112
0.80
0.20
1.3
1.3
12.51
13.26
pmol/l
—
9
93
6
49
1.22
0.20
1.0
1.1
—
—
—
0
0
12
144
0.83
0.19
1.2
1.1
—
—
—
0
0
12
144
0.83
0.19
3.0
4.6
—
—
—
0
0
114
1198
0.95
0.19
1.2
1.1
6.09
7.53
u/ml
0.56
71
696
20
174
1.15
0.19
3.0
2.5
4.60
1.73
ratio
—
10
88
6
51
1.18
0.19
1.3
1.4
—
—
—
0
0
59
549
1.08
0.19
2.8
3.2
7.40
7.41
ph
1.08
59
544
6
52
1.15
0.19
2.0
2.4
80.73
101.26
ng/l
—
6
52
10
81
1.24
0.18
1.2
1.4
16.91
16.57
umol/l
—
10
66
98
1032
0.95
0.18
1.2
1.1
2.04
5.28
u/ml
3.79
54
554
36
394
0.91
0.18
3.4
3.3
4.91
4.91
kpa
0.01
36
389
36
394
0.91
0.18
3.4
3.3
1.28
1.89
mmol/l
1.34
16
215
36
394
0.91
0.18
3.4
3.3
9.30
9.56
kpa
0.49
36
389
7
58
1.21
0.18
1.7
1.3
—
—
—
0
0
10
121
0.83
0.18
1.0
1.2
0.15
0.67
u/ml
—
10
121
90
947
0.95
0.17
1.6
1.6
425.73
362.66
mu/l
0.63
80
777
60
563
1.07
0.16
1.2
1.1
—
—
—
0
0
73
690
1.06
0.16
8.4
3.5
—
—
—
0
0
57
535
1.07
0.16
1.2
1.2
—
—
—
0
0
245
2385
1.03
0.15
1.6
1.6
1284.69
1148.69
nmol/l
0.92
197
1851
6
78
0.77
0.15
1.0
1.1
—
—
—
0
0
20
224
0.89
0.15
1.4
1.3
0.16
0.24
nmol/l
0.45
13
161
155
1604
0.96
0.15
3.2
2.7
0.23
0.23
g/l
0.17
148
1492
28
307
0.91
0.15
1.5
1.3
757.14
1037.78
titre
—
7
45
836
8461
0.98
0.15
3.4
3.0
26.67
28.27
u/l
0.70
812
8074
306
2991
1.03
0.15
2.3
2.2
2.38
2.40
mmol/l
1.85
276
2656
77
732
1.05
0.15
1.4
1.4
84.62
78.96
titre
0.13
13
96
246
2523
0.97
0.14
1.2
1.2
—
—
—
0
0
53
498
1.07
0.14
1.1
1.2
—
—
—
0
0
11
93
1.18
0.14
1.0
1.2
—
0.06
—
0
5
49
522
0.94
0.14
1.2
1.3
—
—
—
0
0
10
84
1.19
0.14
1.7
3.2
13.29
44.26
u/ml
—
10
84
18
201
0.89
0.13
1.2
1.2
—
5.52
—
0
25
78
745
1.05
0.13
4.2
3.5
240.54
437.31
mg/l
1.46
52
358
9
108
0.83
0.13
2.3
3.9
—
—
—
0
0
22
242
0.91
0.13
1.1
1.0
19.16
14.75
u/ml
0.25
16
158
698
6897
1.02
0.13
1.6
1.6
1120.01
980.49
mu/l
2.77
634
6084
14
123
1.14
0.12
1.7
1.3
—
—
—
0
0
65
682
0.95
0.12
2.2
2.1
—
—
—
0
0
766
7743
0.99
0.12
7.5
5.4
1.21
1.22
mmol/l
0.45
725
7187
10
116
0.86
0.12
1.1
1.2
362.50
367.09
u/l
—
10
104
11
95
1.16
0.11
1.6
3.1
—
—
—
0
0
241
2362
1.02
0.11
1.4
1.3
—
—
—
0
0
155
1510
1.03
0.11
2.2
2.4
4.87
5.31
umol/l
0.33
125
1123
13
115
1.13
0.10
1.1
1.1
—
—
—
0
0
22
202
1.09
0.10
1.4
1.3
—
397.14
—
0
7
22
202
1.09
0.10
1.4
1.3
290.00
224.15
titre
—
7
41
13
146
0.89
0.10
3.2
2.1
12.46
13.74
umol/l
0.31
13
146
123
1196
1.03
0.10
1.6
1.4
—
—
—
0
0
5
44
1.14
0.10
1.0
1.3
—
—
—
0
0
346
3511
0.98
0.09
1.3
1.4
3.23
3.29
mmol/l
0.37
201
2217
416
4107
1.01
0.09
1.8
2.1
—
—
—
0
0
56
584
0.96
0.09
11.8
6.9
—
—
—
0
0
62
596
1.04
0.09
1.9
1.6
—
—
—
0
0
6
55
1.09
0.09
1.5
1.5
—
—
—
0
0
5
63
0.79
0.08
1.2
1.4
5.06
5.30
mmol/l
—
5
63
82
845
0.97
0.08
1.9
1.4
124.63
139.53
au/ml
0.41
16
205
26
244
1.07
0.08
1.1
1.2
—
—
—
0
0
6
72
0.83
0.07
1.7
1.2
—
—
—
0
0
84
818
1.03
0.07
3.0
4.2
3.06
21.66
ug/l
1.25
56
562
8
94
0.85
0.06
1.3
1.0
—
—
—
0
0
8
94
0.85
0.06
1.3
1.0
—
—
—
0
0
8
94
0.85
0.06
1.3
1.0
—
—
—
0
0
8
95
0.84
0.06
1.0
2.6
—
—
—
0
0
69
710
0.97
0.06
1.4
1.4
—
1318.33
—
0
12
25
264
0.95
0.06
1.1
1.2
—
—
—
0
0
52
503
1.03
0.06
1.3
1.7
47.49
482.69
pmol/l
—
7
59
436
4396
0.99
0.06
1.4
1.5
3.39
3.34
ratio
0.24
271
3053
87
890
0.98
0.05
1.2
1.2
—
—
—
0
0
17
159
1.07
0.05
5.0
3.2
52.76
43.09
%
1.29
17
159
17
159
1.07
0.05
10.0
6.3
7.65
9.30
%
0.87
17
159
37
357
1.04
0.04
3.1
3.2
—
—
—
0
0
269
2714
0.99
0.04
1.5
1.5
1.23
1.26
mm
0.65
223
2041
382
3847
0.99
0.04
2.1
2.2
—
—
—
0
0
19
180
1.06
0.04
1.7
1.5
—
—
—
0
0
37
382
0.97
0.04
5.4
6.0
363.06
364.07
umol/l
0.02
32
339
13
121
1.07
0.03
1.2
1.1
0.55
3.08
u/ml
0.64
13
107
22
210
1.05
0.03
1.5
1.4
136.29
28.52
u/l
0.41
22
185
247
2490
0.99
0.03
1.4
1.4
—
—
—
0
0
27
260
1.04
0.03
1.1
1.1
—
—
—
0
0
42
431
0.97
0.03
2.9
3.8
64.69
62.77
%
0.22
42
419
89
877
1.02
0.03
1.9
1.4
—
—
—
0
0
283
2847
0.99
0.02
1.5
1.6
—
—
—
0
0
18
188
0.96
0.02
3.6
2.7
0.69
0.81
e9/l
0.51
18
183
1357
13550
1.00
0.02
2.7
2.6
—
10101.80
—
0
10
22
228
0.96
0.02
1.0
1.1
—
—
—
0
0
89
880
1.01
0.02
1.9
1.4
—
28.12
—
0
18
12
127
0.94
0.01
1.3
1.4
0.00
0.00
estimate
-0.00
12
127
34
347
0.98
0.01
1.5
1.3
—
—
—
0
0
36
353
1.02
0.01
2.6
3.6
—
—
—
0
0
418
4170
1.00
0.01
2.0
2.1
—
—
—
0
0
12
126
0.95
0.00
3.2
2.3
28.42
26.60
umol/l
0.28
12
118
28
286
0.98
0.00
1.2
1.1
1526.46
1441.61
miu/ml
0.19
28
286
10
95
1.05
0.00
1.2
1.2
—
3.40
%
—
0
10
15
145
1.03
0.00
1.3
1.1
158.19
185.11
iu/ml
0.22
15
145
16
155
1.03
0.00
1.7
2.6
1.50
1.96
g/24h
—
8
104
17
169
1.01
0.00
1.2
1.1
—
—
—
0
0
52
515
1.01
0.00
1.7
2.5
170.76
330.05
ug/l
1.10
47
462
59
591
1.00
0.00
1.2
1.0
8.46
2.39
eliau/ml
1.05
31
297
17
174
0.98
0.00
1.8
4.4
66.33
182.43
umol/l
—
6
100
72
716
1.01
0.00
1.1
1.1
33.12
16.41
au/ml
0.29
16
213
53
532
1.00
0.00
1.1
1.2
228.77
2850.83
iu/ml
—
10
141
281
2808
1.00
0.00
1.5
1.5
—
—
—
0
0
416
4158
1.00
0.00
2.0
2.0
—
—
—
0
0
414
4142
1.00
0.00
2.0
2.1
—
—
—
0
0
35
347
1.01
0.00
1.1
1.0
0.64
1.54
u/ml
0.55
12
101
16
157
1.02
0.00
1.3
1.4
—
86.74
%
—
0
19
0
8
0.00
0.00
0.0
3.1
—
—
—
0
0
0
8
0.00
0.00
0.0
2.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
0.00
1.4
1.4
—
—
—
0
0
5
54
0.93
0.00
1.8
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
89
0.90
-0.00
1.3
1.5
120.38
134.37
nmol/l
—
8
89
0
5
0.00
-0.00
0.0
1.2
—
29.94
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
207.13
—
0
6
5
53
0.94
-0.00
1.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
7
76
0.92
-0.00
2.1
2.7
530.71
524.64
min
—
7
58
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
451.44
—
0
9
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.6
—
511.11
—
0
9
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.36
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
178.40
—
0
5
13
130
1.00
-0.00
2.5
2.4
1.23
1.12
ug/l
0.06
13
122
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.6
—
18.31
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
0.24
—
0
5
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
79
0.89
-0.00
1.6
1.2
4.74
5.72
mmol/l
—
7
74
6
61
0.98
-0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
27.67
—
0
6

Mortality – FinRegistry

Association

Association between endpoint K11_MAXIL_MOLAR_FAILED_ERUPT_OBSTRUCTION_TOOTH and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
K11_MAXIL_MOLAR_FAILED_ERUPT_OBSTRUCTION_TOOTH 1.312 [0.96, 1.79] 0.089
Birth year 0.984 [0.97, 0.99] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 83 out of 7004 males with K11_MAXIL_MOLAR_FAILED_ERUPT_OBSTRUCTION_TOOTH died.

Mortality risk

Mortality risk for people of age

years, who have K11_MAXIL_MOLAR_FAILED_ERUPT_OBSTRUCTION_TOOTH.

N-year risk Females Males
1 No data 0.197%
5 No data 1.455%
10 No data 3.469%
15 No data 6.725%
20 No data 11.429%

Relationships between endpoints

Index endpoint: K11_MAXIL_MOLAR_FAILED_ERUPT_OBSTRUCTION_TOOTH – Impacted maxillary molar

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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