Ulcerative rectosigmoiditis

ULCERRECT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K51.3
  • Cause of death: ICD-10 K51.3

2 out of 7 registries used, show all original rules.

3874

4. Check minimum number of events

None

3874

5. Include endpoints

None

3874

6. Filter based on genotype QC (FinnGen only)

3588

Control definitions (FinnGen only)

Control exclude
K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K51
Name in latin
Rectosigmoiditis ulcerosa [chronica]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 19206 8881 10235
Only index persons 18415 8651 9764
Unadjusted period prevalence (%)
Whole population 0.27 0.25 0.29
Only index persons 0.35 0.32 0.37
Median age at first event (years)
Whole population 44.63 42.34 46.50
Only index persons 43.93 41.94 45.70

-FinnGen-

Key figures

All Female Male
Number of individuals 3588 1856 1732
Unadjusted period prevalence (%) 0.72 0.66 0.79
Median age at first event (years) 45.68 42.06 49.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3686
Matched controls
36860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L04AC05
ATC
ustekinumab; parenteral
66.0
309.7
170
27
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.1
307.7
1706
6441
UJF32
NOMESCO Finland
Coloscopy
28.2
307.7
2988
4856
A07EA06
ATC
budesonide; oral, local oral
279.6
307.7
1704
113
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
2489.1
307.7
1167
7
H02AB06
ATC
prednisolone; systemic
8.6
307.7
2983
12211
L04AX01
ATC
azathioprine; systemic
76.0
307.7
1566
355
L04AB02
ATC
infliximab; parenteral
144.5
307.7
243
18
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
14.5
307.7
1196
1182
L01BB02
ATC
mercaptopurine; oral
271.2
307.7
630
28
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
307.7
725
*
A07EA02
ATC
hydrocortisone; rectal
714.9
307.7
1816
50
D94
ICPC
Chronic enteritis/ulcerative colitis
306.5
307.7
433
16
A07EA01
ATC
prednisolone; oral, rectal
953.4
307.7
423
5
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
+∞
307.7
532
*
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
307.7
568
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
31.0
307.7
441
161
K51
ICD-10 Finland
Ulcerative colitis
1442.6
307.7
794
7
K51.5
ICD-10 Finland
Left sided colitis
10296.5
307.7
2271
5
H02AB07
ATC
prednisone; oral
6.4
307.7
1128
2372
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
5449.4
307.7
2199
10
A07EC02
ATC
mesalazine; oral, rectal
5557.3
307.7
3498
123
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
307.7
3466
*
UJF30
NOMESCO Finland
Ileoscopy through colon
18.9
307.7
1719
1629
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
71.0
307.7
276
42
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
307.7
3686
*
K51.8
ICD-10 Finland
Other ulcerative colitis
3930.9
307.7
933
*
A07EC01
ATC
sulfasalazine; oral, rectal
10.1
307.7
1013
1333
K50.8
ICD-10 Finland
Other Crohn disease
+∞
300.2
284
*
K50.1
ICD-10 Finland
Crohn disease of large intestine
1584.0
299.9
288
*
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
35.2
286.5
181
54
K50.9
ICD-10 Finland
Crohn disease, unspecified
729.1
278.0
271
*
ZX120
NOMESCO Finland
Intravenous
4.9
265.6
665
1574
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
351.6
264.2
264
8
L04AB04
ATC
adalimumab; parenteral
9.8
239.0
285
311
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
232.8
221
*
A07EC03
ATC
olsalazine; oral
+∞
195.6
186
*
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
34.4
193.7
123
37
253, ,
Kela drug reimbursment
+∞
190.3
181
*
3042, ,
Kela drug reimbursment
+∞
189.2
180
*
J01MA02
ATC
ciprofloxacin; systemic
2.7
180.7
1745
9301
4AA12, ,
NOMESCO Finland
82.1
180.6
96
12
4AB02, ,
NOMESCO Finland
48.9
172.1
100
21
K50.0
ICD-10 Finland
Crohn disease of small intestine
+∞
171.2
163
*
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
169.1
161
*
P01AB01
ATC
metronidazole; oral, rectal
2.5
163.2
1809
10160
L04AG05
ATC
vedolizumab; parenteral
+∞
154.3
147
*
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
154.3
147
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
140.9
1042
4763
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
693.4
136.6
134
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
126.5
1212
6207
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.2
124.8
361
935
L04AA33
ATC
[U] vedolizumab
+∞
124.7
119
*
Z93.2
ICD-10 Finland
Ileostomy status
43.2
120.4
72
17
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
315.2
120.0
121
*
A06AC01
ATC
ispaghula (psylla seeds); oral
2.4
119.3
1085
5406
3005
Kela drug reimbursment
Tofacitinib
24.8
113.2
80
33
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
112.0
107
*
L04AD01
ATC
ciclosporin; systemic
7.1
110.4
169
247
L04AF03
ATC
upadacitinib; oral
32.4
108.4
70
22
256, ,
Kela drug reimbursment
+∞
106.8
102
*
1370
FHL
Colonoscopy, whole colon
31.9
106.4
69
22
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
12.5
106.4
105
86
L04AB06
ATC
golimumab; parenteral
11.2
104.4
111
102
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
+∞
101.5
97
*
298, ,
Kela drug reimbursment
23.9
94.9
68
29
C05AA08
ATC
fluocortolone; rectal, topical
2.7
93.5
607
2550
3029
Kela drug reimbursment
Upadacitinib
21.6
91.3
68
32
UJF92
NOMESCO Finland
Capsular endoscopy
7.1
91.2
140
205
L04AA29
ATC
[U] tofacitinib
20.4
89.0
68
34
K83.0
ICD-10 Finland
Cholangitis
8.7
87.8
112
132
WX002
NOMESCO Finland
Sedation and analgesia
2.3
85.3
764
3712
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
31.0
84.0
55
18
JFF10
NOMESCO Finland
Loop enterostomy
15.9
83.9
72
46
A07DA03
ATC
loperamide; oral
5.1
82.6
179
366
A02BC02
ATC
pantoprazole; systemic
2.0
81.7
2583
19732
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
+∞
81.6
78
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
81.3
1744
11685
WVA20
NOMESCO Finland
Medicine administration
4.8
80.4
189
414
A07AA09
ATC
vancomycin; oral
8.2
79.9
107
134
C10AC01
ATC
colestyramine; oral
5.5
77.0
152
286
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
15.0
76.8
68
46
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.4
76.4
298
939
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.1
75.2
160
322
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.5
72.0
261
784
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
72.0
829
4427
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
16.0
70.1
60
38
UJF34
NOMESCO Finland
Left colonoscopy
12.9
68.3
66
52
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
67.9
65
*
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
+∞
67.9
65
*
JFH11
NOMESCO Finland
Laparoscopic colectomy
+∞
66.9
64
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.1
66.3
290
978
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
64.6
422
1761
JF1BD
NOMESCO Finland
Very extensive small bowel CT
22.7
64.2
47
21
JFH10
NOMESCO Finland
Total colectomy and ileostomy
138.5
64.1
68
5
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
+∞
63.7
61
*
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
+∞
62.7
60
*
H02AB09
ATC
hydrocortisone; systemic
4.7
62.5
149
330
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.2
62.2
131
261
A05AA02
ATC
ursodeoxycholic acid; oral
5.7
62.2
118
214
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.5
60.6
406
1713
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.7
59.5
199
566
L04AX03
ATC
methotrexate; systemic
2.4
57.0
427
1895
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.9
56.6
286
1044
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
12.3
56.5
56
46
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.1
56.4
623
3245
D16
ICPC
Rectal bleeding
4.2
53.7
145
354
K92.1
ICD-10 Finland
Melaena
3.2
53.5
218
703
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
53.2
51
*
4AA33, ,
NOMESCO Finland
+∞
52.2
50
*
UJG02
NOMESCO Finland
Proctoscopy
4.5
50.8
127
292
H02AB04
ATC
methylprednisolone; systemic
2.1
50.7
547
2816
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
5.7
50.3
94
168
TJF80
NOMESCO Finland
Ostomy education
7.0
49.6
76
111
JF2AB
NOMESCO Finland
Colongraphy with X-ray
19.2
48.4
38
20
UJF30, ,
SPAT
7.0
47.0
72
105
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.2
43.9
424
2085
JF1AD
NOMESCO Finland
Small bowel CT
10.1
43.4
49
49
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
43.2
502
2646
L04AA01
ATC
[U] ciclosporin
5.7
42.8
80
143
K50
ICD-10 Finland
Crohn disease [regional enteritis]
148.4
41.8
44
*
Z93
ICD-10 Finland
Artificial opening status
16.1
40.9
35
22
M45
ICD-10 Finland
Ankylosing spondylitis
3.9
40.8
120
312
3AC01, ,
NOMESCO Finland
6.8
40.7
64
96
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
40.4
501
2698
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
+∞
38.6
37
*
A02BC03
ATC
lansoprazole; oral
1.7
37.4
935
6214
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
37.3
835
5387
N02AX02
ATC
tramadol; systemic, rectal
1.6
36.4
1467
10930
56902
ICD-8 Finland
Other diseases of intestines and peritoneum, Proctitis haemorrhagica (ulcerosa)
+∞
35.5
34
*
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
+∞
35.5
34
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
35.4
1317
9618
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
35.3
491
2742
D18
ICPC
Change in faeces/bowel movements
3.4
35.1
128
385
JAH00
NOMESCO Finland
Laparotomy
3.6
33.8
114
326
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
33.4
32
*
L01BA01
ATC
methotrexate; systemic
3.0
33.4
147
496
N02BE01
ATC
paracetamol; systemic, rectal
1.8
33.4
3210
28956
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
3.9
32.3
97
256
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
4.4
32.3
82
191
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
4.5
31.8
77
173
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.5
31.5
197
799
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
31.1
1577
12221
K60.3
ICD-10 Finland
Anal fistula
3.7
30.5
96
262
A02BC01
ATC
omeprazole; systemic
1.6
30.5
864
5879
A02BC05
ATC
esomeprazole; systemic
1.5
29.9
1365
10328
R50.9
ICD-10 Finland
Fever, unspecified
1.7
28.9
548
3352
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
10.4
28.9
32
31
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
9.8
28.5
33
34
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.6
28.4
169
670
JHA00
NOMESCO Finland
Anal or perianal incision
4.0
28.3
81
207
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.3
28.2
47
75
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.2
27.3
255
1231
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
27.0
1526
11981
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
26.8
755
5108
ZXC86
NOMESCO Finland
Use of endoscopic device
6.8
26.3
41
61
K56.7
ICD-10 Finland
Ileus, unspecified
4.2
25.9
68
163
C05AA01
ATC
hydrocortisone; rectal, topical
2.4
25.5
173
730
WW200
NOMESCO Finland
Immunization
2.9
25.4
120
422
B01AB05
ATC
enoxaparin; parenteral
1.5
24.7
952
6894
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.1
24.5
105
349
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
4.2
24.3
65
158
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.9
24.0
338
1886
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.2
23.6
92
289
A03CA02
ATC
clidinium and psycholeptics; oral
2.4
23.4
167
721
D06BX01
ATC
metronidazole; topical
1.8
23.4
370
2141
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
2.9
23.3
113
403
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.2
23.2
90
282
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
+∞
22.9
22
*
WZC30
NOMESCO Finland
Teaching
1.6
22.8
550
3571
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.0
22.5
97
324
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
4.3
22.3
58
138
SPAT1263
SPAT
Sampling
1.4
22.3
1347
10598
J01MA12
ATC
levofloxacin; systemic
1.6
22.0
567
3740
JGB40
NOMESCO Finland
Excision of rectum and end ileostomy
+∞
21.9
21
*
Z43.2
ICD-10 Finland
Attention to ileostomy
25.2
21.7
30
12
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
21.7
411
2502
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.3
21.7
168
751
UJF02
NOMESCO Finland
Peroral enteroscopy
7.4
21.6
31
42
K61.0
ICD-10 Finland
Anal abscess
3.3
21.4
82
255
1490
FHL
Sigmoideoscopy (fiberscope)
19.0
21.2
32
17
D11
ICPC
Diarrhoea
1.7
21.1
440
2750
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
3.0
20.8
94
323
A06AC51
ATC
ispaghula, combinations; oral
2.3
20.6
154
678
SPAT1131
SPAT
Colonoscopy
2.8
20.5
103
375
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
18.9
19.9
30
16
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
19.9
281
1568
1380
FHL
Colonoscopy, left side
+∞
19.8
19
*
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
+∞
19.8
19
*
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
6.5
19.2
31
48
D99
ICPC
Disease digestive system other
4.3
19.0
49
116
ZXE00
NOMESCO Finland
One hour or less
1.4
18.9
1230
9734
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
14.2
18.5
31
22
JFF13
NOMESCO Finland
Terminal enterostomy
15.1
18.4
30
20
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.7
18.2
101
387
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.3
18.1
133
582
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
18.0
1228
9772
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.9
18.0
243
1337
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
17.8
1400
11396
L04AF01
ATC
tofacitinib; oral
20.1
17.7
26
13
-, ,
ICD-10 Finland
2.9
17.2
82
290
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
4.1
17.0
46
113
K56.0
ICD-10 Finland
Paralytic ileus
4.7
16.6
38
82
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
6.0
16.5
29
49
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
16.5
1022
7983
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.2
16.4
138
640
M05BA04
ATC
alendronic acid; oral
1.9
16.4
194
1022
J05AB01
ATC
aciclovir; systemic
1.5
16.3
690
5034
J01DB01
ATC
cefalexin; oral
1.4
16.1
2906
26699
JHD00
NOMESCO Finland
Anal dilatation
4.7
16.1
37
80
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
3.4
16.0
57
170
SPAT1262
SPAT
Handing over of treatment supplies
1.5
15.9
494
3385
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
15.9
1232
9960
D07AC01
ATC
betamethasone; topical
1.4
15.8
1168
9372
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
15.7
212
1167
Z2221
NOMESCO Finland
Medical doctor
1.4
15.6
851
6493
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
15.6
780
5863
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.5
15.5
101
419
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
15.5
296
1802
J01FA10
ATC
azithromycin; systemic
1.3
15.5
1991
17308
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
3.2
15.4
60
189
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
2.7
15.2
79
293
M13.9
ICD-10 Finland
Arthritis, unspecified
1.8
15.2
247
1438
B02.9
ICD-10 Finland
Zoster without complication
1.9
15.1
201
1101
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
14.9
222
1258
E0000UV, ,
ATC
1.3
14.8
1342
11074
JFB00
NOMESCO Finland
Partial resection of small intestine
3.6
14.7
48
135
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
6.1
14.7
25
41
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
14.5
339
2175
K52.1
ICD-10 Finland
Toxic gastroenteritis and colitis
150.6
14.5
15
*
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
150.6
14.5
15
*
A03BA03
ATC
hyoscyamine; oral
4.7
14.5
33
71
WX402
NOMESCO Finland
General anaesthesia
1.4
14.4
739
5569
OAB50, ,
SPAT
1.7
14.4
255
1521
JHD20
NOMESCO Finland
Incision of fistula-in-ano
3.6
14.3
47
133
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
3.2
14.2
55
173
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
4.4
14.0
34
77
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
2.2
14.0
123
581
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.2
13.9
111
505
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.7
13.8
262
1592
L04AA44
ATC
[U] upadacitinib
10.5
13.7
26
25
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
2.3
13.7
107
482
A98
ICPC
Health maint/preventive medicine
2.0
13.6
3557
34371
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.9
13.6
170
912
R01AD08
ATC
fluticasone; nasal
1.4
13.5
951
7538
R01AD12
ATC
fluticasone furoate; nasal
1.3
13.5
1090
8819
H15.1
ICD-10 Finland
Episcleritis
2.9
13.3
60
207
UJH02
NOMESCO Finland
Anoscopy
2.1
13.2
128
629
SPAT1301
SPAT
No procedures
1.4
13.2
885
6961
A02BA02
ATC
ranitidine; systemic
1.5
13.1
504
3598
WZA90
NOMESCO Finland
Other medical or dental certificate
1.4
13.1
748
5734
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
16.8
13.0
20
12
Z3231
NOMESCO Finland
Registered nurse
1.4
13.0
800
6206
6419
FHL
Other measure in this category
28.5
12.9
17
6
L88
ICD-10 Finland
Pyoderma gangrenosum
13.0
12.9
22
17
SPAT1153
SPAT
Removal of sutures
1.4
12.8
884
6978
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.8
12.7
208
1214
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
12.7
251
1543
UJD02
NOMESCO Finland
Gastroscopy
2.0
12.6
133
674
Y0599
ICD-8 Finland
Investigation of digestive system
3.1
12.5
52
171
B80
ICPC
Iron deficiency anaemia
2.4
12.5
88
379
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
12.5
711
5441
JGA05
NOMESCO Finland
Endoscopic polypectomy in rectum
5.2
12.5
25
48
J05AB11
ATC
valaciclovir; oral
1.5
12.4
444
3125
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.2
12.4
106
496
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
12.3
1191
9853
SPAT1255
SPAT
Intravenous administration of medicine
1.8
12.3
193
1112
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
12.3
305
1984
A07AA11
ATC
rifaximin; oral
5.8
12.3
22
38
SPAT1325
SPAT
Vaccination
1.3
11.9
871
6924
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
11.8
303
1987
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
11.7
545
4029
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
12.6
11.6
20
16
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
11.5
320
2136
JGB61
NOMESCO Finland
Laparoscopic excision of rectum and ileoanal anastomosis
+∞
11.5
11
*
K74.3
ICD-10 Finland
Primary biliary cirrhosis
4.7
11.4
26
56
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.8
11.4
173
988
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.4
11.4
39
114
Z01.2
ICD-10 Finland
Dental examination
1.3
11.3
1580
13664
K76.9
ICD-10 Finland
Liver disease, unspecified
3.1
11.3
47
155
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.3
11.3
83
365
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
8.9
11.2
23
26
J01AA02
ATC
doxycycline; systemic
1.3
11.2
2569
23592
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
8.0
11.1
24
30
UJK02
NOMESCO Finland
ERCP
2.4
11.0
75
319
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
11.0
1199
10043
A07AA02
ATC
nystatin; oral
1.8
11.0
150
829
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
11.0
1839
16234
UJK12
NOMESCO Finland
Peroral cholangioscopy
11.9
10.8
19
16
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
2.7
10.8
55
203
B03BA03
ATC
hydroxocobalamin; parenteral
1.9
10.8
128
676
N03AX16
ATC
[U] pregabalin
1.4
10.7
655
5056
ZYC01
NOMESCO Finland
Remote contact by phone
1.7
10.7
205
1250
UJF32, ,
SPAT
2.0
10.6
109
548
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.7
10.6
192
1154
K59.1
ICD-10 Finland
Functional diarrhoea
1.8
10.6
155
877
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
10.5
680
5293
J02AC01
ATC
fluconazole; systemic
1.3
10.4
1193
10039
3048, ,
Kela drug reimbursment
110.3
10.4
11
*
255, ,
Kela drug reimbursment
110.3
10.4
11
*
JFH31
NOMESCO Finland
Laparoscopic total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
+∞
10.4
10
*
L04AA45
ATC
[U] filgotinib
+∞
10.4
10
*
SPAT1125
SPAT
Stoma care and guidance
3.2
10.4
41
131
B01AB10
ATC
tinzaparin; parenteral
1.5
10.3
302
2037
D29
ICPC
Digestive symptom/complaint other
2.2
10.1
84
389
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
3.0
10.1
43
144
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
10.1
894
7275
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
2.9
10.1
45
155
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
10.1
2484
22834
L88
ICPC
Rheumatoid/seropositive arthritis
1.9
10.0
122
651
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
10.0
2524
23253
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
4.6
10.0
23
50
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
40.2
10.0
12
*
J01CA04
ATC
amoxicillin; systemic
1.3
9.9
2853
26709
ZXD05
NOMESCO Finland
Urgent procedure
1.3
9.8
912
7465
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
2.9
9.8
44
152
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
9.8
2340
21392
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
2.5
9.6
59
240
J01MA01
ATC
ofloxacin; systemic
1.6
9.5
209
1321
5551A
ICD-9 Finland
Regional enteritis, Large intestine
+∞
9.4
9
*
5589X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis, Other and unspecified non-infectious gastro-enteritis and colitis
+∞
9.4
9
*
5563A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctosigmoiditis
+∞
9.4
9
*
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
+∞
9.4
9
*
6410
FHL
Panprococolectomy and ileostomy
+∞
9.4
9
*
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.0
9.4
97
490
UKC02
NOMESCO Finland
Cystoscopy
1.4
9.3
400
2908
D17
ICPC
Incontinence of bowel
3.5
9.3
31
89
R03AC02
ATC
salbutamol; inhalant
1.2
9.3
1788
15909
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
9.3
183
1125
D07AD01
ATC
clobetasol; topical
1.4
9.3
481
3614
K60.4
ICD-10 Finland
Rectal fistula
9.5
9.3
18
19
NH3EA
NOMESCO Finland
Feet X-ray examination with load
2.4
9.2
61
257
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
9.2
1008
8411
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
9.2
574
4441
0093A
ICD-9 Finland
Ill-defined intestinal infections, Diarrhoea of presumed infectious origin
2.7
9.1
46
170
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
2.7
9.1
46
170
M81.4
ICD-10 Finland
Drug-induced osteoporosis
4.8
9.1
20
42
R05
ICPC
Cough
1.3
9.0
752
6057
N05CF01
ATC
zopiclone; oral
1.3
8.9
889
7326
S18
ICPC
Laceration/cut
1.2
8.9
1421
12369
SFA10
NOMESCO Finland
One-surface restoration
1.2
8.9
1866
16725
Z01.9
ICD-10 Finland
Special examination, unspecified
1.7
8.9
172
1052
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
8.9
864
7097
M25.5
ICD-10 Finland
Pain in joint
1.3
8.8
1066
8996
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
1.8
8.7
115
631
H04.10
ICD-10 Finland
Dry eye syndrome
1.4
8.6
347
2494
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
7.3
8.4
19
26
B81
ICPC
Anaemia vit B12/folate deficiency
2.0
8.4
86
433
K91.8
ICD-10 Finland
Other postprocedural disorders of digestive system, not elsewhere classified
12.8
8.4
14
11
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
+∞
8.3
8
*
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
+∞
8.3
8
*
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
1.9
8.3
104
561
JAH01
NOMESCO Finland
Laparoscopy
1.8
8.3
131
759
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.3
8.3
875
7255
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
8.2
1055
8947
I84.1
ICD-10 Finland
Internal hemorrhoids with other complications
2.2
8.2
65
297
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
8.1
310
2208
M01AE01
ATC
ibuprofen; systemic, rectal
0.8
8.1
2948
30853
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
1.9
8.0
97
518
SPAT1138
SPAT
Guidance concerning bowel function
2.7
8.0
40
147
R51.80
ICD-10 Finland
Headache
1.3
8.0
490
3775
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
8.0
1755
15742
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.4
8.0
362
2659
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.7
7.9
133
785
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
7.9
627
5012
K02.1
ICD-10 Finland
Caries of dentine
1.2
7.9
2044
18627
6451
FHL
Dilatation
3.6
7.8
25
70
E86
ICD-10 Finland
Volume depletion
2.2
7.8
60
271
SPAT1312
SPAT
General health counselling
1.3
7.8
913
7659
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.1
7.7
69
331
K52.80
ICD-10 Finland
(Hemorrhagic) colitis caused by antibiotics
45.1
7.7
9
*
R05
ICD-10 Finland
Cough
1.3
7.7
628
5036
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.5
7.7
84
1546
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
7.6
1523
13510
N82.3
ICD-10 Finland
Fistula of vagina to large intestine
18.4
7.6
11
6
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.3
7.5
528
4148
SPAT1260
SPAT
Consultation of another employee
1.3
7.5
464
3579
M01AH01
ATC
celecoxib; oral
1.3
7.4
449
3450
M81.9
ICD-10 Finland
Osteoporosis, unspecified
1.9
7.4
93
503
H20
ICD-10 Finland
Iridocyclitis
3.4
7.4
25
73
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
7.3
245
1700
D07XC01
ATC
betamethasone; topical
1.4
7.3
335
2462
D07AC13
ATC
mometasone; topical
1.3
7.3
852
7130
SCA02
NOMESCO Finland
Preventive oral health care
1.4
7.3
300
2164
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
2.7
7.3
38
143
H26.3
ICD-10 Finland
Drug-induced cataract
3.6
7.3
23
64
D07AB08
ATC
desonide; topical
1.4
7.3
299
2158
5781B
ICD-9 Finland
Gastro-intestinal haemorrhage, Melaena[HAEMORRHAGIA EX ANO]
9.4
7.3
14
15
D62
ICPC
Digestive, Administrative procedure
4.1
7.3
19
46
H20.1
ICD-10 Finland
Chronic iridocyclitis
2.8
7.3
34
121
E000001, ,
ATC
1.3
7.3
564
4492
JG1JB
NOMESCO Finland
Defekography with X-ray
3.3
7.2
26
79
R01AD09
ATC
mometasone; nasal
1.2
7.2
1488
13217
M03BX02
ATC
tizanidine; oral
1.2
7.2
2073
19004
J31.0
ICD-10 Finland
Chronic rhinitis
1.4
7.2
262
1850
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.4
7.2
268
1901
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.5
7.1
189
1250
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.0
7.1
76
391
J01DA01
ATC
[U] cefalexin
1.2
7.0
1956
17853
Z71.8
ICD-10 Finland
Other specified counselling
1.2
7.0
1080
9310
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.7
7.0
114
668
S21
ICPC
Skin texture symptom/complaint
1.3
7.0
415
3183
D50.8
ICD-10 Finland
Other iron deficiency anaemias
2.4
6.9
46
195
J45.1
ICD-10 Finland
Nonallergic asthma
1.5
6.9
186
1234
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
2.3
6.9
50
220
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
6.9
808
6763
SFA20
NOMESCO Finland
Two-surface restoration
1.2
6.9
1993
18244
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
2.5
6.8
39
154
K62.6
ICD-10 Finland
Ulcer of anus and rectum
2.7
6.8
35
131
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
6.8
491
3869
K30
ICD-10 Finland
Functional dyspepsia
1.4
6.7
330
2456
SCA01
NOMESCO Finland
Preventive oral health care, short
1.2
6.7
896
7607
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
2.0
6.7
73
378
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
2.0
6.6
72
372
JHD33
NOMESCO Finland
Completing incision of fistula-in-ano
6.4
6.6
16
25
D04
ICPC
Rectal/anal pain
2.3
6.6
46
200
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
1.7
6.6
107
628
JFH00
NOMESCO Finland
Total colectomy and ileorectal anastomosis
8.7
6.5
13
15
K43.5
ICD-10 Finland
Parastomal hernia without obstruction or gangrene
8.7
6.5
13
15
S02.51
ICD-10 Finland
Fracture of tooth, open
1.4
6.5
268
1934
EB1VA, ,
NOMESCO Finland
1.3
6.5
565
4561
D28
ICPC
Limited function/disability (D)
6.8
6.5
15
22
L95
ICPC
Osteoporosis
1.9
6.5
79
425
G04CA02
ATC
tamsulosin; oral
1.3
6.4
576
4668
JN4AD
NOMESCO Finland
Body CT examination
1.4
6.4
282
2060
M02AA10
ATC
ketoprofen; topical
1.3
6.4
414
3212
JD1AB
NOMESCO Finland
Gastro-duodenography with X-ray
14.3
6.4
10
7
A01AB09
ATC
miconazole; local oral
1.5
6.4
200
1372
ZXE30
NOMESCO Finland
More than five and less than seven hours
1.7
6.4
115
694
J01MA14
ATC
moxifloxacin; systemic
1.4
6.4
242
1723
L52
ICD-10 Finland
Erythema nodosum
3.0
6.3
26
86
KMAK, ,
NOMESCO Finland
1.2
6.3
1694
15355
A03FA01
ATC
metoclopramide; systemic, rectal
1.3
6.3
595
4854
N06AX11
ATC
mirtazapine; oral
1.2
6.3
1015
8777
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
2.2
6.3
50
230
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
2.2
6.3
50
230
ZYY98
NOMESCO Finland
Missed treatment contact, no notification given by patient
3.8
6.3
18
47
1CB02, ,
NOMESCO Finland
+∞
6.2
6
*
4AG05, ,
NOMESCO Finland
+∞
6.2
6
*
392
Kela drug reimbursment
Ferric maltol
+∞
6.2
6
*
M073, K519,
ICD-10 Finland
+∞
6.2
6
*
K52.0
ICD-10 Finland
Gastroenteritis and colitis due to radiation
+∞
6.2
6
*
M02AA07
ATC
piroxicam; topical
1.2
6.2
934
8014
WVA20, ,
SPAT
1.7
6.2
101
592
JFG96
NOMESCO Finland
Other operation on intestinal stoma or pouch
26.7
6.2
8
*
D06BB10
ATC
imiquimod; topical
1.6
6.2
136
862
SPAT1104
SPAT
Monitoring of emergency patient
1.5
6.2
158
1037
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
2.4
6.2
41
174
M25.9
ICD-10 Finland
Joint disorder, unspecified
2.5
6.2
37
150
M05BX04
ATC
denosumab; parenteral
1.6
6.2
124
770
D64.9
ICD-10 Finland
Anaemia, unspecified
1.4
6.2
237
1692
Z94.4
ICD-10 Finland
Liver transplant status
5.3
6.1
17
32
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
7.7
6.1
13
17
SFA00
NOMESCO Finland
Small restoration
1.3
6.1
415
3244
-60
ICPC
Result test/procedure
1.6
6.1
144
930
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.4
6.1
222
1569
A02BA04
ATC
nizatidine; systemic
1.5
6.1
162
1075
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
6.1
300
2236
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.2
6.0
816
6925
K62.4
ICD-10 Finland
Stenosis of anus and rectum
6.7
6.0
14
21
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
1.8
6.0
88
501
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.6
6.0
145
941
D01
ICPC
Abdominal pain/cramps general
1.3
6.0
351
2684
K56.2
ICD-10 Finland
Volvulus
3.5
6.0
20
58

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
3504
23632
10.78
316.26
19.9
7.5
72.75
77.35
u/l
13.50
3459
22562
406
494
9.11
314.49
4.8
3.2
3.88
4.08
e9/l
0.91
406
494
925
2546
4.52
308.66
7.0
4.3
0.42
0.76
%
4.99
246
736
2820
15254
4.61
307.65
15.3
6.2
28.92
28.39
%
2.12
2756
14548
2971
3619
38.17
307.65
8.8
1.3
222.16
93.91
ug/g
42.60
2871
2818
2795
14746
4.70
307.65
15.4
6.2
2.84
2.83
%
0.04
2723
13917
3057
16229
6.18
307.65
15.4
6.1
0.04
0.04
e9/l
2.69
2852
14068
3066
16594
6.04
307.65
15.5
6.1
1.87
1.95
e9/l
3.62
2888
14755
437
48
103.15
307.65
3.4
2.6
8.93
5.32
mg/l
5.57
370
34
3056
16196
6.19
307.65
15.4
6.0
0.56
0.57
e9/l
1.30
2853
14045
1809
7663
3.67
307.65
3.9
2.1
2.67
2.71
mg/l
0.38
1686
6641
3087
16763
6.18
307.65
15.6
6.3
0.19
0.19
e9/l
0.93
2899
14775
361
49
81.56
307.65
2.8
2.3
142.48
164.86
au/ml
0.13
56
11
3127
18107
5.79
307.65
16.6
9.4
3.88
4.08
e9/l
7.01
2907
15778
2802
15001
4.62
307.65
14.8
6.1
56.87
56.88
%
0.02
2744
14411
2783
14754
4.62
307.65
15.6
6.3
0.76
0.68
%
15.72
2708
13912
2810
14784
4.79
307.65
15.5
6.3
8.86
8.73
%
1.92
2736
13962
2986
12963
7.86
307.65
10.1
4.8
36.98
36.24
g/l
15.68
2924
12204
2716
13852
4.65
307.65
4.3
2.3
76.32
75.53
nmol/l
0.84
2648
12763
2380
2947
20.97
307.65
2.3
1.2
—
—
—
0
0
942
2673
4.39
301.39
7.3
4.5
0.67
0.93
%
1.77
255
772
925
2606
4.40
298.54
7.9
4.8
0.06
0.23
%
0.69
227
620
914
2575
4.39
294.67
7.4
4.6
0.05
0.10
%
2.09
225
673
423
633
7.42
273.98
4.9
3.0
57.02
57.91
%
0.66
423
633
183
66
29.12
272.99
2.3
1.3
9.67
9.07
mg/l
0.37
161
53
1656
7685
3.10
239.24
11.3
4.3
—
—
—
0
0
1070
3979
3.38
223.15
3.8
3.2
3.91
4.76
e9/l
3.99
966
3539
3265
23059
4.64
217.68
8.3
4.0
11.36
10.53
mm/h
3.26
3151
21762
2398
14173
2.98
214.50
20.0
10.4
0.00
0.00
e9/l
0.96
2151
11561
197
0
+∞
207.26
2.6
0.0
24.29
—
mg/l
—
190
0
623
1698
4.21
204.92
1.5
1.2
—
—
—
0
0
1091
4341
3.15
200.43
1.5
1.7
—
—
—
0
0
128
47
28.18
189.34
1.8
1.3
82.65
177.40
au/ml
—
20
5
1283
6069
2.71
166.18
1.7
1.7
—
—
—
0
0
370
928
4.32
133.76
1.5
1.2
68.33
104.95
titre
2.34
42
93
1849
11232
2.30
130.39
4.5
3.2
28.67
34.62
u/l
3.08
1683
10668
2335
15823
2.30
124.00
4.4
3.1
101.86
116.58
ug/l
1.75
2256
14987
902
4257
2.48
110.61
3.0
2.6
22.77
24.02
%
2.17
866
3994
235
479
5.17
109.18
1.1
1.2
—
—
—
0
0
285
682
4.45
109.02
1.2
1.2
253.15
257.74
u/ml
0.09
176
427
999
5028
2.35
105.41
3.1
2.6
13.68
13.93
umol/l
0.49
959
4723
944
4664
2.38
103.70
3.0
2.5
2.40
2.35
g/l
2.45
904
4347
2284
16036
2.12
101.37
7.7
6.4
10.32
11.40
umol/l
7.28
2215
15328
514
1936
2.92
97.93
1.9
1.9
1.28
1.36
g/l
0.42
486
1804
1548
9667
2.04
91.68
4.3
2.6
58.42
59.14
u/l
0.18
1478
9019
594
2503
2.64
90.80
2.6
2.9
11.21
10.67
g/l
2.59
557
2317
1284
7519
2.09
90.43
1.9
2.0
—
—
—
0
0
3586
31482
6.13
89.03
29.3
13.9
15.15
23.42
mg/l
81.30
3279
25628
583
2471
2.61
87.87
4.6
3.6
—
—
—
0
0
893
4781
2.15
77.77
1.6
1.4
514.61
494.30
titre
0.14
230
951
338
1145
3.15
76.92
1.8
1.7
—
—
—
0
0
346
1190
3.11
76.72
1.2
1.2
—
—
—
0
0
1881
13274
1.85
71.34
13.6
12.9
1.17
1.21
inr
3.59
1648
11009
1792
12529
1.84
69.34
2.5
2.0
—
—
—
0
0
55
30
18.60
69.11
2.5
2.1
2.44
1.21
mg/l
3.39
49
25
1018
5947
1.98
68.62
2.7
1.6
7391731.04
35512964.33
pmol/l
2.00
920
5063
573
2844
2.20
58.89
2.7
2.2
0.23
0.22
g/l
5.77
538
2667
1341
9000
1.77
55.98
4.4
3.7
0.00
0.00
estimate
2.17
666
3143
2186
16861
1.73
54.91
4.2
3.6
1.48
0.11
estimate
0.45
679
3192
2176
16781
1.72
54.51
4.2
3.6
5.17
5.14
estimate
0.00
704
3412
2154
16601
1.72
53.73
4.2
3.5
0.00
0.00
estimate
0.80
699
3370
117
243
4.94
52.97
1.4
1.2
55.10
61.52
u/l
0.53
107
215
1749
12780
1.70
52.84
4.2
3.4
0.05
0.07
estimate
0.17
629
2785
762
4371
1.94
52.24
2.2
1.7
1169.94
1160.88
nmol/l
0.08
496
3392
256
928
2.89
51.26
1.2
1.3
—
—
—
0
0
1926
14623
1.66
48.83
7.9
7.2
1.21
1.21
mmol/l
1.93
1665
12734
1050
6855
1.74
46.46
1.7
1.5
2.63
2.37
g/l
3.25
743
4494
1340
9374
1.67
45.78
3.7
3.0
0.00
0.15
estimate
0.84
621
2667
177
561
3.26
44.66
1.9
1.5
0.68
0.80
g/l
0.74
134
430
1164
7901
1.69
44.25
4.7
4.4
—
—
—
0
0
1340
9442
1.66
44.11
9.5
6.2
—
—
—
0
0
548
2975
1.99
43.42
1.4
1.5
—
—
—
0
0
3088
27029
1.88
42.69
30.2
17.1
13.63
13.48
%
10.89
3078
26686
92
188
4.99
42.46
1.1
1.1
1445.30
1487.04
miu/ml
0.13
92
188
1242
8663
1.65
42.07
4.5
4.2
7.40
7.40
ph
0.57
926
6119
1723
13057
1.60
41.39
7.2
6.5
1.21
1.21
mmol/l
2.40
1622
12155
215
799
2.80
41.00
1.4
1.1
—
—
—
0
0
3602
33671
4.06
40.87
33.3
17.4
76.40
76.37
umol/l
0.02
3586
33332
1757
13484
1.58
39.23
3.5
3.2
6.06
6.20
ph
6.89
1115
7758
101
239
4.32
38.96
1.5
1.2
275.79
157.14
titre
0.82
38
35
3585
33548
3.50
37.85
26.2
10.9
26.47
27.73
u/l
4.60
3565
32783
283
1288
2.30
35.15
1.7
1.5
8.66
21.00
iu/ml
0.92
25
29
254
1104
2.40
35.05
1.6
1.2
—
—
—
0
0
3433
31606
2.26
34.92
21.5
16.0
139.58
139.70
mmol/l
2.55
3377
31016
136
427
3.27
34.84
4.1
3.7
0.96
1.54
%
1.25
127
399
3438
31710
2.25
34.14
21.7
16.1
3.92
3.96
mmol/l
19.95
3377
31051
69
133
5.27
34.05
14.6
28.3
134.69
117.93
ug/l
1.11
61
110
1657
13025
1.49
30.21
2.1
2.0
96.02
96.86
pmol/l
0.31
971
7119
193
818
2.43
28.12
1.9
1.4
6.35
8.60
iu/ml
—
8
16
1103
8107
1.51
27.11
1.7
1.6
20.51
19.90
nmol/l
0.70
975
7056
513
3133
1.74
27.10
2.4
2.2
332.03
377.29
nmol/l
6.15
481
2919
1068
7825
1.51
26.53
1.4
1.3
1.10
1.74
u/ml
2.10
307
2246
643
4229
1.63
25.55
1.3
1.2
—
—
—
0
0
2150
18195
1.44
24.44
5.8
4.9
6.68
6.64
mmol/l
0.41
2041
17144
568
3669
1.65
24.13
3.5
2.8
6.16
7.72
umol/l
2.03
498
3222
31
37
8.44
24.00
1.9
2.1
—
—
—
0
0
78
221
3.58
23.52
1.6
1.5
—
—
—
0
0
60
145
4.19
22.61
1.6
1.7
2954.55
3217.78
titre
0.09
22
18
122
476
2.62
21.19
1.1
1.1
1.51
1.48
g/l
0.28
113
431
471
3011
1.65
20.65
3.2
2.5
47.10
53.67
u/l
0.14
409
2558
158
715
2.26
19.85
1.4
1.5
—
—
—
0
0
249
1337
1.92
19.83
1.1
1.1
—
—
—
0
0
128
555
2.35
17.79
1.4
1.2
70.00
292.31
titre
—
6
13
167
810
2.11
17.68
3.1
3.0
1.17
2.09
index
2.07
102
436
143
657
2.22
17.35
1.4
1.5
151.56
149.57
au/ml
0.06
36
188
475
3172
1.57
17.22
3.3
2.8
1.86
1.79
%
0.72
430
2856
79
274
2.92
17.21
4.4
3.9
55.80
57.01
%
0.21
71
249
3604
34840
2.55
16.58
40.3
21.2
91.71
90.67
fl
36.68
3595
34552
3604
34841
2.55
16.56
40.3
21.1
30.48
30.29
pg
8.86
3595
34553
2264
19955
1.35
16.55
4.7
4.2
364.65
1637.30
e6/l
1.88
26
259
3603
34829
2.53
16.52
40.5
21.3
268.81
252.65
e9/l
37.14
3586
34255
881
6709
1.41
16.49
3.1
2.7
5.82
5.81
e6/l
0.01
824
6101
3604
34845
2.54
16.48
41.0
21.7
40.97
41.36
%
0.98
3593
34539
3604
34845
2.54
16.48
40.4
21.2
4.50
4.57
e12/l
15.04
3582
34183
3604
34852
2.53
16.35
40.5
21.3
6.76
6.70
e9/l
0.82
3581
34184
3604
34855
2.53
16.29
40.7
21.4
136.19
137.44
g/l
6.72
3594
34570
187
976
1.96
16.20
5.3
3.5
104.26
4272.42
u/ml
0.88
165
852
375
2401
1.63
16.18
3.0
2.9
75.01
71.52
e9/l
0.84
289
1753
352
2227
1.64
15.93
4.2
3.7
1.23
1.23
mmol/l
0.07
320
1933
1016
7999
1.37
15.41
5.4
4.0
93.28
91.51
%
1.70
983
7838
766
5761
1.42
15.23
1.3
1.3
5.20
10.18
u/ml
2.51
292
2391
608
4404
1.46
14.80
2.3
2.1
—
—
—
0
0
680
5038
1.43
14.64
3.8
3.5
0.81
0.82
mmol/l
1.50
647
4791
241
1416
1.75
14.35
1.8
1.9
5.60
6.78
iu/ml
0.47
68
357
543
3881
1.47
14.12
6.8
6.6
1.01
1.04
mmol/l
1.76
515
3630
1051
8466
1.34
13.37
3.5
3.1
0.41
0.39
e6/l
0.10
819
6111
1198
9836
1.32
13.35
3.6
3.3
53.80
106.02
e6/l
1.08
968
7426
1345
11265
1.31
12.85
3.7
3.4
39.93
59.71
ng/l
0.77
883
7116
83
349
2.41
12.46
1.3
1.3
—
—
—
0
0
803
6279
1.36
12.28
1.3
1.3
16.73
27.83
iu/ml
5.43
232
1844
258
1621
1.64
11.98
1.1
1.1
36.67
130.02
titre
—
6
49
125
634
2.01
11.82
3.5
3.8
—
—
—
0
0
82
352
2.36
11.77
1.3
1.3
0.33
0.39
g/l
0.77
50
249
907
7266
1.33
11.72
1.9
1.8
1.14
1.06
mg/l
0.44
708
5509
82
353
2.35
11.70
1.3
1.3
2.66
3.02
g/l
0.99
51
252
82
353
2.35
11.70
1.3
1.3
7.49
6.66
g/l
0.92
51
251
729
5688
1.35
11.19
3.2
2.8
555.30
541.10
mosm/kgh2o
0.79
668
4987
1350
11481
1.28
10.98
4.1
3.8
83.90
86.97
e6/l
0.03
1025
7933
216
1327
1.67
10.96
1.3
1.2
0.20
0.78
u/ml
1.58
11
109
389
2735
1.47
10.89
4.3
4.3
5.63
19.09
ug/l
2.58
296
2191
110
553
2.02
10.70
4.3
3.6
100.23
885.41
u/ml
1.03
99
517
1174
9841
1.28
10.64
3.3
3.3
0.75
0.68
—
8
25
67
276
2.45
10.57
1.1
1.1
—
—
—
0
0
2550
23485
1.28
10.34
4.2
3.3
49.20
45.19
u/l
1.52
2425
22428
167
985
1.73
9.87
3.4
3.4
1.39
1.48
mg/l
0.80
153
918
359
2547
1.45
9.57
1.4
1.4
—
—
—
0
0
502
3780
1.38
9.55
1.7
1.7
—
—
—
0
0
1200
10204
1.26
9.40
3.7
3.4
2.35
2.35
mmol/l
0.57
1118
9393
14
8
17.56
9.39
1.1
1.0
—
—
—
0
0
392
2873
1.41
8.73
2.0
2.0
0.02
0.01
estimate
0.20
82
656
108
583
1.88
8.61
3.8
4.2
2.49
2.43
mmol/l
0.09
68
374
165
1013
1.66
8.45
1.6
1.8
0.22
0.23
g/l
0.97
157
970
983
8248
1.26
8.45
3.2
2.8
—
—
—
0
0
59
256
2.33
8.38
4.3
4.5
—
—
—
0
0
170
1056
1.64
8.32
1.5
1.8
1.19
1.19
g/l
0.13
162
1011
2657
24889
1.24
7.76
4.1
4.2
14.76
14.59
pmol/l
3.25
2492
23181
1650
14753
1.21
7.60
3.3
2.7
—
—
estimate
—
0
0
137
827
1.68
7.52
1.6
1.4
293.61
291.16
ug/g
0.05
84
475
89
475
1.90
7.40
2.0
2.2
6.26
5.73
umol/l
0.20
59
347
28
89
3.16
7.25
1.1
1.3
—
—
—
0
0
881
7429
1.24
7.06
4.0
3.7
1.02
1.43
kg/l
0.80
600
4857
3071
29342
1.28
7.04
4.9
5.1
1.69
1.84
mu/l
12.58
2911
27573
105
613
1.73
6.56
1.1
1.1
—
—
—
0
0
197
1346
1.49
6.42
1.2
1.2
—
—
—
0
0
1066
9251
1.21
6.38
2.3
2.2
237.83
226.96
u/l
0.06
1014
8819
505
4034
1.29
6.32
1.7
1.5
—
—
—
0
0
1067
9281
1.21
6.20
2.9
2.7
0.21
0.04
0.55
14
151
186
1278
1.48
5.92
1.8
1.8
1.50
1.51
g/l
0.05
168
1124
320
2423
1.35
5.85
2.7
2.5
0.30
0.42
e6/l
0.87
312
2298
351
2704
1.33
5.72
9.2
8.1
9.03
9.25
mmol/l
0.25
332
2620
138
899
1.56
5.65
1.7
2.2
11.44
11.15
mg/l
0.13
128
846
58
296
1.97
5.59
1.1
1.1
273.61
287.11
mg/l
0.70
51
271
341
2625
1.33
5.59
4.6
4.1
7.37
7.35
ph
1.18
263
1914
46
216
2.14
5.53
2.2
3.1
247.26
225.78
e6/l
0.18
35
191
258
1912
1.38
5.42
3.7
3.6
5.06
5.16
kpa
1.51
252
1844
365
2850
1.31
5.41
4.7
3.8
1.91
1.84
mmol/l
0.12
324
2487
967
8427
1.20
5.39
2.6
2.6
332.95
339.58
umol/l
1.25
872
7607
509
4153
1.26
5.34
1.3
1.3
—
—
—
0
0
16
34
4.72
5.29
1.5
1.5
—
—
—
0
0
862
7452
1.20
5.21
3.9
3.5
0.50
0.16
—
6
62
375
2958
1.30
5.16
4.8
3.8
7.38
7.38
ph
0.03
221
1665
250
1860
1.37
5.14
3.7
3.6
7.42
7.42
ph
0.34
215
1554
71
400
1.79
5.09
1.3
1.3
34.73
54.06
u/ml
—
6
21
56
293
1.93
5.06
2.1
2.8
1479.16
1202.44
e6/l
1.07
45
264
32
136
2.36
4.89
1.7
1.6
2.83
4.03
%
—
6
32
1141
10162
1.18
4.87
2.8
2.4
—
—
—
0
0
149
1023
1.48
4.82
1.3
1.2
46.07
42.24
u/ml
—
7
54
244
1829
1.36
4.80
2.4
2.5
—
—
—
0
0
898
7856
1.19
4.71
3.2
3.1
1113.26
1133.51
ng/l
0.06
761
6632
298
2309
1.32
4.69
2.5
2.7
67.84
66.89
g/l
1.36
280
2163
12
22
5.47
4.59
1.6
1.0
—
—
—
0
0
186
1348
1.40
4.51
3.5
3.1
1.02
1.02
ratio
0.08
173
1217
19
65
2.93
4.44
1.1
1.2
—
—
—
0
0
236
1783
1.35
4.43
6.9
7.0
24.43
24.45
mmol/l
0.03
227
1704
177
1279
1.40
4.38
2.6
1.9
—
—
—
0
0
42
211
2.00
4.31
2.2
2.9
538.06
527.76
e6/l
0.04
31
177
362
2920
1.27
4.20
4.9
3.8
5.84
5.84
kpa
0.03
353
2835
137
954
1.45
4.17
1.3
1.3
8.76
6.91
u/ml
0.12
18
79
294
2317
1.29
4.11
1.3
1.3
166.54
203.24
u/ml
0.55
280
2156
137
959
1.45
4.07
1.3
1.3
11.78
7.85
u/ml
0.48
25
133
537
4545
1.21
3.99
1.5
1.5
—
—
—
0
0
126
873
1.46
3.95
5.5
5.6
1.24
1.31
mmol/l
0.58
116
756
63
375
1.69
3.82
3.3
2.2
1.04
0.89
%
1.09
48
253
33
159
2.09
3.82
1.2
1.1
137.28
190.55
iu/ml
0.95
33
159
615
5295
1.19
3.81
3.0
2.8
0.82
1.02
e6/l
0.84
343
2735
155
1128
1.39
3.73
1.9
2.0
10.26
1.87
ug/l
0.48
147
1015
200
1517
1.34
3.71
2.0
2.1
0.01
0.50
estimate
0.50
72
515
331
2685
1.26
3.68
1.1
1.2
—
—
—
0
0
27
122
2.22
3.66
4.3
5.0
—
—
—
0
0
56
327
1.72
3.66
1.9
1.7
44.38
57.47
%
1.34
34
207
111
767
1.46
3.57
3.6
3.5
1.62
2.79
ratio
1.08
68
424
13
36
3.62
3.49
1.6
1.8
—
—
—
0
0
93
624
1.50
3.46
1.1
1.1
—
—
—
0
0
111
776
1.44
3.38
1.3
1.2
29.51
43.62
u/ml
—
9
73
365
3033
1.23
3.28
9.6
8.6
96.81
95.77
%
4.67
350
2938
83
551
1.52
3.27
2.0
1.6
—
—
—
0
0
262
2100
1.27
3.25
1.4
1.4
25.27
25.39
iu/l
0.02
220
1789
345
2857
1.23
3.20
10.0
9.1
121.51
123.53
g/l
1.06
338
2793
121
869
1.41
3.19
3.7
3.7
44.76
58.67
mg/l
0.83
100
743
45
258
1.75
3.17
1.7
1.6
35.10
33.77
%
0.07
23
165
10
289
0.34
3.12
17.0
20.4
1291.50
1393.50
nmol/l
—
10
282
296
2421
1.24
3.09
2.6
2.3
5.94
6.10
ph
2.36
193
1554
61
383
1.60
3.08
3.9
2.5
—
—
—
0
0
100
699
1.44
3.08
2.5
2.3
131.91
132.01
g/l
0.01
89
559
120
870
1.39
3.02
3.7
3.6
40.98
69.27
mg/l
0.81
100
745
112
1531
0.72
2.91
1.4
2.3
—
—
—
0
0
7
13
5.39
2.87
1.0
1.0
0.08
0.08
—
7
8
25
122
2.06
2.86
1.1
1.1
—
—
—
0
0
92
644
1.44
2.83
1.2
1.1
29.00
15.93
au/ml
0.53
26
189
259
2114
1.24
2.78
4.1
4.2
92.90
89.28
ng/l
0.19
228
1878
310
2579
1.22
2.78
11.2
9.6
—
—
—
0
0
45
269
1.68
2.78
1.3
1.1
—
—
—
0
0
144
1091
1.33
2.77
1.9
2.4
7.16
7.28
g/l
0.35
131
1021
144
1091
1.33
2.77
1.9
2.4
3.86
3.67
g/l
0.87
131
1021
144
1091
1.33
2.77
1.9
2.4
4.35
4.20
g/l
0.87
131
1021
61
916
0.66
2.68
1.7
1.6
—
—
—
0
0
2276
21808
1.11
2.61
4.0
3.7
10013.56
11445.78
—
9
36
159
1236
1.30
2.57
4.8
3.4
24.96
25.37
mmol/l
0.72
153
1189
850
7715
1.13
2.57
2.8
2.3
—
—
—
0
0
24
121
1.99
2.55
3.3
4.7
65.74
62.02
mg/l
0.14
19
89
629
5609
1.15
2.48
2.8
2.9
2.44
2.44
mmol/l
0.61
562
5037
124
937
1.33
2.47
1.9
2.4
11.29
10.48
g/l
0.76
109
863
396
3411
1.18
2.46
9.2
8.3
7.42
7.41
ph
0.63
237
1890
31
174
1.79
2.41
1.2
1.1
—
—
—
0
0
141
1809
0.77
2.41
1.4
2.3
—
—
—
0
0
95
691
1.38
2.41
1.8
2.4
0.95
0.90
nmol/l
0.19
85
595
642
5748
1.14
2.39
3.3
3.6
611.78
467.45
ng/l
0.26
434
4130
36
212
1.70
2.39
1.1
1.1
1.05
1.06
ratio
0.35
31
173
78
549
1.43
2.39
1.1
1.2
—
—
—
0
0
61
892
0.68
2.38
1.6
1.5
—
—
—
0
0
60
879
0.68
2.37
1.6
1.5
1.26
1.27
mm
0.06
47
623
59
394
1.51
2.35
2.6
2.4
—
—
—
0
0
395
3417
1.17
2.34
9.3
8.2
5.07
5.12
kpa
0.55
379
3299
149
1165
1.29
2.34
5.9
5.2
0.96
0.88
%
1.52
142
1094
395
3418
1.17
2.34
9.3
8.2
12.90
12.66
kpa
0.42
379
3296
392
3391
1.17
2.33
9.2
8.2
0.89
0.89
mmol/l
0.00
325
2790
134
1034
1.31
2.32
1.9
2.4
2.97
2.89
g/l
0.46
121
965
21
106
1.99
2.25
3.3
2.9
0.64
0.63
mmol/l
0.14
21
106
548
4878
1.14
2.23
3.1
3.0
2.59
2.41
e6/l
0.15
271
2310
34
202
1.69
2.21
1.3
1.4
1.30
1.29
nmol/l
0.02
29
152
205
1679
1.23
2.19
13.0
10.9
16.54
16.24
%
0.83
200
1615
101
758
1.34
2.14
1.1
1.1
—
—
—
0
0
286
2428
1.19
2.13
4.5
3.1
4.44
4.66
kpa
1.25
278
2352
159
1270
1.26
2.13
5.6
5.0
1.56
1.66
%
0.90
152
1195
519
4618
1.14
2.13
2.7
2.2
29.64
29.60
s
0.06
503
4500
101
760
1.34
2.11
1.1
1.1
—
—
—
0
0
159
1272
1.26
2.11
2.5
2.1
20.66
20.93
s
0.27
137
1119
269
2277
1.20
2.08
2.8
2.2
5.55
8.06
ug/l
1.80
242
2058
5
10
5.01
2.07
1.0
1.0
187.20
298.80
u/ml
—
5
10
63
440
1.44
2.05
1.6
1.5
55.66
78.15
mu/l
0.52
54
403
46
301
1.53
2.05
2.1
2.2
16.10
21.82
mg/l
0.82
21
120
44
286
1.54
2.02
1.1
1.1
21.78
16.71
u/ml
0.33
13
126
12
50
2.40
2.02
2.8
3.3
31.30
28.30
mg/l
—
5
13
58
401
1.45
2.00
1.3
1.3
—
—
—
0
0
74
536
1.39
1.98
1.2
1.2
—
—
—
0
0
299
3468
0.85
1.98
1.6
1.7
3.42
3.50
mmol/l
0.67
187
2345
159
1956
0.80
1.96
1.3
2.2
—
—
—
0
0
39
249
1.57
1.95
1.3
1.1
—
—
—
0
0
52
354
1.48
1.94
3.3
2.6
—
—
—
0
0
122
957
1.28
1.92
1.2
1.1
—
—
—
0
0
67
480
1.40
1.92
1.3
1.7
—
—
—
0
0
159
1947
0.81
1.89
1.3
2.1
—
—
—
0
0
410
4625
0.87
1.87
1.8
1.9
3.55
3.57
ratio
0.11
298
3496
20
107
1.87
1.86
1.2
1.0
—
—
—
0
0
5
12
4.17
1.82
1.0
1.0
—
—
—
0
0
59
820
0.71
1.81
1.5
3.0
—
—
—
0
0
200
1676
1.20
1.76
1.8
1.8
0.26
0.31
mg/l
0.71
92
836
87
1132
0.76
1.74
1.6
1.5
59.91
59.02
ug/l
0.08
74
939
9
193
0.47
1.72
1.1
3.1
—
—
—
0
0
312
2723
1.16
1.71
9.9
8.1
1.26
1.33
mmol/l
0.88
305
2669
31
194
1.60
1.71
2.0
2.9
1157.77
912.99
u/ml
0.38
31
194
40
266
1.51
1.71
4.5
3.2
11.52
13.03
index
0.74
25
175
49
340
1.45
1.70
1.2
1.4
—
—
—
0
0
210
2473
0.84
1.69
1.2
1.2
88.78
151.60
u/ml
2.26
79
932
161
1938
0.82
1.65
1.3
2.3
—
—
—
0
0
389
3458
1.14
1.65
2.3
2.4
13.14
13.53
nmol/l
0.43
356
3172
37
244
1.52
1.65
1.0
1.2
—
—
—
0
0
370
4152
0.88
1.59
1.3
1.4
—
—
—
0
0
77
585
1.32
1.58
4.6
3.9
—
—
—
0
0
18
99
1.82
1.57
2.9
2.6
—
—
—
0
0
162
1350
1.21
1.55
1.3
1.3
258.50
223.57
miu/ml
0.50
69
641
161
1923
0.83
1.54
1.3
2.2
—
—
—
0
0
36
240
1.50
1.54
1.2
1.2
—
—
—
0
0
214
1832
1.18
1.52
4.9
3.1
130.17
131.47
g/l
0.34
206
1780
21
123
1.71
1.50
1.0
1.1
—
—
—
0
0
1016
9557
1.09
1.49
3.8
3.6
48.77
50.71
mg/l
0.10
687
6280
87
680
1.29
1.48
1.4
1.5
71.39
136.09
pmol/l
1.67
87
666
6
22
2.73
1.43
1.0
1.1
—
—
—
0
0
6
22
2.73
1.43
1.0
1.0
—
—
—
0
0
71
544
1.31
1.41
2.2
2.0
5.60
5.28
mmol/24h
0.30
64
492
18
103
1.75
1.40
3.3
3.3
—
—
—
0
0
185
1579
1.18
1.39
2.4
2.4
7180.46
5952.56
u/l
0.20
67
626
26
166
1.57
1.37
1.5
1.3
—
—
—
0
0
20
120
1.67
1.34
1.1
1.1
—
—
—
0
0
112
915
1.23
1.34
1.2
1.1
—
—
—
0
0
13
68
1.91
1.33
1.0
1.2
—
—
—
0
0
36
249
1.45
1.32
1.1
1.1
8.82
8.17
iu/ml
—
8
81
34
233
1.46
1.31
2.2
2.9
0.70
0.70
e9/l
0.02
34
226
49
360
1.37
1.30
1.1
1.1
—
—
—
0
0
38
267
1.43
1.29
1.1
1.2
—
—
—
0
0
110
1333
0.82
1.27
1.5
3.2
—
—
—
0
0
2828
27746
1.08
1.27
30.3
17.6
332.17
333.26
g/l
8.82
2821
27591
123
1022
1.21
1.26
2.7
2.6
—
—
—
0
0
62
475
1.31
1.26
1.5
1.4
57.62
63.62
mmol/l
0.57
39
389
1024
9709
1.08
1.21
4.6
4.2
8.79
8.84
mg/mmol
0.01
678
6269
28
188
1.49
1.21
4.0
7.6
457.59
110.12
ug/l
0.34
21
126
32
221
1.45
1.21
1.2
1.2
—
—
—
0
0
136
1604
0.84
1.19
1.1
1.1
0.60
0.65
ratio
0.46
14
175
39
282
1.39
1.16
1.3
1.2
—
—
—
0
0
53
689
0.77
1.14
1.4
1.3
—
—
—
0
0
34
241
1.41
1.13
1.2
1.2
0.57
0.61
ratio
0.28
20
141
92
752
1.23
1.13
1.7
1.7
18798.51
12387.72
e6/l
0.26
69
524
1081
10296
1.07
1.12
4.9
4.9
2.30
2.31
ug/l
0.01
999
9403
16
257
0.62
1.10
1.4
1.5
—
—
—
0
0
147
1261
1.17
1.09
1.5
1.4
10.30
9.14
u/l
0.58
120
1018
41
303
1.36
1.09
1.0
1.1
259.19
281.41
mg/l
0.39
36
261
70
558
1.26
1.08
1.2
1.3
3.32
4.10
u/ml
0.35
38
263
1417
13631
1.06
1.08
2.0
1.9
1.42
1.41
mmol/l
0.19
1206
11772
17
105
1.62
1.06
1.2
1.3
111.85
138.99
nmol/l
0.37
12
78
30
211
1.43
1.06
1.0
1.0
—
—
—
0
0
11
60
1.84
1.02
1.0
1.2
—
—
—
0
0
11
60
1.84
1.02
1.0
1.2
—
—
—
0
0
11
60
1.84
1.02
1.0
1.2
—
—
—
0
0
17
261
0.65
0.98
1.5
1.6
—
—
—
0
0
11
61
1.81
0.98
7.2
6.3
4.64
5.52
kpa
2.36
11
61
5
23
2.18
0.98
1.2
1.1
—
—
—
0
0
183
2071
0.88
0.97
1.5
1.7
—
—
—
0
0
3207
31710
1.09
0.97
5.0
4.8
4.63
4.68
mmol/l
2.07
3052
30194
150
1304
1.16
0.97
3.9
3.7
—
—
—
0
0
18
116
1.55
0.96
1.0
1.0
—
—
—
0
0
110
1291
0.85
0.96
1.6
1.4
—
—
—
0
0
3051
30114
1.08
0.95
4.8
4.7
5.87
5.87
mmol/l
0.07
2862
28157
49
381
1.29
0.95
1.1
1.4
—
—
nmol/l
—
0
0
71
578
1.23
0.95
1.1
1.1
16.17
1049.63
iu/ml
0.56
15
132
11
62
1.78
0.94
1.6
2.5
—
—
—
0
0
107
908
1.18
0.94
1.0
1.1
0.93
4.82
eliau/ml
2.96
11
133
18
117
1.54
0.93
1.3
1.2
28.61
28.76
s
0.03
18
117
25
175
1.43
0.92
5.2
3.4
0.64
0.85
index
0.94
25
175
34
453
0.75
0.92
4.6
3.9
39.76
25.79
u/ml
0.27
34
441
228
2048
1.12
0.91
2.7
2.8
164.29
174.15
ng/l
0.15
204
1858
41
313
1.31
0.91
1.1
1.2
50.14
42.88
mg/l
0.32
34
257
11
63
1.75
0.90
1.8
2.9
80.33
166.02
ng/l
—
6
31
34
253
1.35
0.90
1.1
1.2
—
—
—
0
0
35
262
1.34
0.89
2.5
2.3
—
—
—
0
0
12
71
1.69
0.88
1.3
1.2
16.03
13.65
pmol/l
—
6
27
22
152
1.45
0.88
1.9
1.6
—
—
—
0
0
51
404
1.27
0.87
2.4
2.3
—
—
—
0
0
20
136
1.47
0.86
1.1
1.1
11.00
203.00
ng/l
—
7
31
28
204
1.38
0.85
1.9
1.4
5.92
6.95
u/l
0.46
20
178
48
602
0.79
0.84
3.0
3.2
27.09
25.55
mg/l
0.12
34
414
81
680
1.20
0.82
2.5
3.0
27.33
35.39
umol/l
4.06
76
624
49
390
1.26
0.82
1.2
1.3
0.21
0.22
nmol/l
0.12
38
308
52
417
1.25
0.82
1.4
1.4
537.26
310.50
pmol/l
1.14
43
360
30
223
1.35
0.81
1.0
1.0
—
—
—
0
0
17
114
1.49
0.79
1.1
1.1
—
—
—
0
0
28
373
0.75
0.78
1.5
1.6
—
—
—
0
0
18
123
1.47
0.77
1.0
1.1
—
—
—
0
0
5
100
0.50
0.77
1.0
1.4
—
—
—
0
0
146
1293
1.13
0.77
1.8
1.7
9.78
13.23
u/ml
0.42
27
349
1109
10695
1.05
0.75
3.6
3.5
8.64
8.08
mmol/l
3.26
962
9274
30
227
1.32
0.74
1.6
1.4
94.67
79.47
umol/l
0.49
30
227
1024
9862
1.05
0.73
1.6
1.5
—
—
—
0
0
27
202
1.34
0.72
2.1
3.0
36.40
42.00
%
—
10
100
11
68
1.62
0.71
2.6
2.3
—
—
—
0
0
17
117
1.46
0.71
1.2
1.6
0.00
0.05
estimate
0.80
17
117
56
462
1.22
0.71
1.2
1.4
1.64
0.29
nmol/l
—
5
25
7
41
1.71
0.70
1.3
1.3
29.14
718.07
u/l
—
7
31
9
58
1.55
0.69
1.0
1.0
7.94
6.50
u/ml
—
9
58
29
221
1.31
0.69
2.0
2.4
807.00
623.25
ml
1.70
20
153
21
152
1.38
0.69
2.3
2.6
26.34
226.74
ug/l
0.66
21
136
10
156
0.64
0.67
2.1
2.6
50.00
51.70
umol/l
—
10
141
66
560
1.18
0.64
2.2
1.9
—
—
—
0
0
8
129
0.62
0.63
1.0
1.0
—
—
—
0
0
41
332
1.24
0.63
3.2
3.1
20.91
20.70
nmol/l
0.00
41
322
18
130
1.39
0.61
2.3
2.7
—
—
—
0
0
3184
31577
1.06
0.61
4.9
4.7
1.45
1.43
mmol/l
2.51
3017
29916
34
271
1.26
0.60
1.3
1.4
331547.33
97231.91
e6/l
0.43
21
187
29
227
1.28
0.59
1.1
1.1
341.12
396.32
nmol/l
0.83
23
206
207
2246
0.92
0.58
1.2
1.2
—
—
—
0
0
42
345
1.22
0.58
3.6
2.5
1.30
1.50
g/24h
0.22
29
208
20
265
0.75
0.58
1.4
1.5
14965.93
79022.94
e6/l
1.79
14
159
6
35
1.72
0.57
1.8
2.0
1.38
1.41
umol/l
—
6
22
57
668
0.85
0.56
1.1
1.1
2.85
3.75
u/ml
0.19
28
326
17
124
1.37
0.55
1.9
2.3
32.47
30.95
%
0.15
17
124
16
116
1.38
0.54
2.4
2.8
—
—
—
0
0
3225
32018
1.06
0.54
5.4
5.3
2.71
2.78
mmol/l
4.56
3059
30360
31
249
1.25
0.53
1.1
1.2
104.94
110.12
pmol/l
0.27
31
249
16
118
1.36
0.50
2.2
1.6
1021.94
377.23
nmol/24h
0.28
16
118
50
584
0.85
0.49
1.0
1.0
0.42
0.31
u/ml
0.13
13
180
331
3497
0.94
0.48
4.6
4.5
31.95
31.30
%
0.55
244
2426
166
1532
1.09
0.47
1.5
1.7
275.69
287.63
mu/l
0.29
152
1402
40
336
1.19
0.47
1.3
1.3
1.55
1.52
nmol/l
0.07
31
304
19
146
1.30
0.47
1.4
1.6
0.58
0.51
e9/l
0.52
19
146
52
601
0.86
0.46
1.4
1.2
—
—
—
0
0
87
778
1.12
0.46
1.2
1.3
—
—
—
0
0
2993
29688
1.04
0.46
6.1
5.7
38.66
38.67
mmol/mol
0.02
2852
28229
66
748
0.88
0.45
1.1
1.1
2.10
1.55
u/ml
0.26
36
354
7
50
1.40
0.45
2.1
1.4
—
—
—
0
0
7
51
1.37
0.44
1.3
1.3
1.94
1.53
mmol/l
—
7
35
108
982
1.10
0.43
8.5
9.1
—
—
—
0
0
38
321
1.19
0.43
1.0
1.1
—
—
—
0
0
70
787
0.89
0.43
1.1
1.1
5.96
5.32
u/ml
0.11
33
423
0
15
0.00
0.41
0.0
2.1
—
250.00
—
0
10
0
15
0.00
0.41
0.0
2.1
—
202.67
—
0
9
0
15
0.00
0.41
0.0
5.2
—
469.67
—
0
15
21
168
1.25
0.40
1.2
1.2
24.56
36.20
mmol/l
1.39
16
156
0
18
0.00
0.40
0.0
1.0
—
0.13
—
0
10
16
124
1.29
0.38
1.8
2.2
6.44
7.24
%
0.19
16
119
59
524
1.13
0.37
1.2
1.4
2.52
3.91
ug/l
1.63
54
475
19
152
1.25
0.37
3.3
2.0
98.07
121.99
ng/l
0.52
19
152
115
1061
1.09
0.36
2.5
2.4
229.52
424.14
ug/l
1.82
106
1006
55
619
0.89
0.36
1.0
1.1
4.46
4.50
u/ml
0.01
25
271
110
1013
1.09
0.36
4.0
3.6
816.47
428.95
mg/l
0.41
58
468
5
76
0.66
0.35
1.6
1.3
—
0.23
—
0
10
36
310
1.16
0.35
4.0
5.5
61.78
64.27
u/ml
0.02
13
97
17
135
1.26
0.35
1.8
1.7
—
—
—
0
0
47
415
1.13
0.33
3.1
3.4
0.80
0.81
nmol/l
0.05
40
339
88
809
1.09
0.31
1.1
1.3
3.55
3.72
mmol/l
0.97
82
767
76
694
1.10
0.31
1.5
1.5
0.41
0.39
nmol/l
0.07
58
537
37
323
1.15
0.31
1.9
1.8
21.66
25.18
ug/l
0.17
37
317
17
138
1.23
0.30
1.1
1.2
—
0.12
g/l
—
0
12
28
323
0.87
0.28
1.8
1.4
1.26
1.29
promille
0.02
21
253
40
355
1.13
0.28
2.0
2.1
-0.43
0.55
mmol/l
0.94
40
345
16
131
1.22
0.27
1.8
1.7
—
—
—
0
0
8
65
1.23
0.27
1.0
1.0
0.22
4.39
u/ml
—
8
58
13
161
0.81
0.27
1.1
1.3
119.44
173.22
mmol/24h
1.94
13
161
12
95
1.26
0.26
2.3
1.7
—
—
—
0
0
11
86
1.28
0.26
1.2
1.5
—
—
—
0
0
24
207
1.16
0.25
1.0
1.0
298.79
299.00
ng/l
0.00
19
148
33
292
1.13
0.25
2.2
2.7
—
—
—
0
0
83
891
0.93
0.24
1.1
1.1
2.18
2.18
u/ml
0.00
40
460
17
142
1.20
0.24
2.0
3.0
131.00
129.48
umol/l
—
10
82
86
921
0.93
0.24
2.4
2.1
3.74
9.79
iu/l
0.52
36
398
108
1016
1.06
0.24
4.6
3.7
24.78
24.83
mmol/l
0.08
100
944
6
84
0.71
0.24
1.0
1.1
11.63
38.65
iu/ml
—
6
84
70
755
0.93
0.24
1.1
1.1
0.69
1.26
u/ml
0.88
27
316
5
38
1.32
0.23
6.6
9.0
0.18
0.20
%
—
5
38
13
106
1.23
0.23
1.1
1.7
40.73
40.35
g/l
0.07
13
106
10
125
0.80
0.23
8.0
6.5
9.90
8.11
%
—
10
125
10
125
0.80
0.23
4.0
3.2
41.00
45.44
%
—
10
125
7
95
0.74
0.22
2.0
2.1
—
—
—
0
0
17
144
1.18
0.22
2.2
1.9
—
—
—
0
0
26
229
1.14
0.21
1.8
1.9
6.87
6.69
mmol/l
0.13
17
162
0
11
0.00
0.21
0.0
1.0
—
0.95
—
0
11
0
11
0.00
0.21
0.0
1.1
—
0.01
—
0
6
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
85
798
1.07
0.21
1.3
1.4
136.96
35.62
e6/l
0.37
70
586
29
258
1.13
0.21
1.2
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
347.92
—
0
13
0
13
0.00
0.21
0.0
1.8
—
1918.54
—
0
13
56
605
0.92
0.20
1.3
1.2
—
—
—
0
0
80
753
1.06
0.19
1.4
1.4
—
—
—
0
0
23
204
1.13
0.18
1.0
1.0
734.87
770.48
ng/l
0.20
15
144
217
2241
0.97
0.18
1.3
1.3
39.26
52.01
au/ml
0.53
16
149
65
610
1.07
0.17
1.3
1.4
29.75
24.56
u/l
0.58
56
502
7
61
1.15
0.17
3.3
3.1
5.86
61.79
ug/l
—
7
61
190
1964
0.97
0.17
1.7
1.6
1130.20
1010.86
mu/l
0.77
158
1630
3019
30085
1.02
0.16
4.2
4.1
1.30
1.31
mmol/l
0.54
2839
28315
44
409
1.08
0.15
1.5
1.5
—
—
—
0
0
6
79
0.76
0.15
1.0
1.5
32.67
26.36
%
—
6
74
9
78
1.15
0.15
1.0
1.1
—
—
—
0
0
37
342
1.08
0.15
1.2
1.5
275.55
281.48
mosm/kgh2o
0.95
31
260
15
171
0.88
0.14
2.2
2.2
10.07
8.07
mmol/l
0.58
15
171
85
811
1.05
0.14
1.4
1.5
733.47
1253.52
e6/l
0.39
75
631
16
141
1.14
0.14
1.2
1.1
—
—
—
0
0
19
170
1.12
0.13
1.1
1.2
—
—
—
0
0
31
287
1.08
0.12
1.2
1.3
0.21
1.49
u/ml
1.71
14
155
105
1088
0.96
0.12
1.8
1.9
—
—
—
0
0
71
680
1.04
0.11
2.5
2.4
81.32
118.03
ug/min
0.43
43
424
22
239
0.92
0.10
1.0
1.1
0.89
2.21
u/ml
—
7
46
34
319
1.07
0.10
5.0
3.6
11.21
10.61
mmol/l
0.46
34
314
11
96
1.15
0.10
1.2
1.1
—
—
—
0
0
11
96
1.15
0.10
1.2
1.1
—
—
—
0
0
11
96
1.15
0.10
1.2
1.1
—
—
—
0
0
5
44
1.14
0.10
1.0
1.0
—
—
—
0
0
5
44
1.14
0.10
9.4
10.8
6.12
5.96
mmol/l
—
5
44
5
47
1.06
0.09
1.8
3.0
—
—
—
0
0
615
6213
0.99
0.09
2.8
3.0
0.77
0.73
ug/l
0.46
379
3687
43
409
1.05
0.09
1.6
1.5
—
—
—
0
0
43
409
1.05
0.09
1.6
1.5
—
—
—
0
0
43
409
1.05
0.09
1.6
1.5
—
—
—
0
0
5
60
0.83
0.08
1.2
1.1
0.06
0.10
u/ml
—
5
60
17
185
0.92
0.08
1.1
1.4
140.97
134.56
nmol/l
0.31
17
185
16
146
1.10
0.08
1.1
1.0
13.11
11.62
u/ml
—
10
101
11
123
0.89
0.08
1.2
1.4
70.91
73.07
%
0.18
11
118
6
73
0.82
0.07
1.2
1.4
—
—
—
0
0
8
74
1.08
0.07
1.8
1.2
—
—
—
0
0
8
75
1.07
0.07
1.8
1.3
62.25
30.90
%
—
8
50
26
276
0.94
0.07
1.7
1.6
7.57
7.62
mmol/l
0.04
26
266
58
561
1.03
0.06
1.2
1.3
23.68
43.72
u/l
1.63
49
483
238
2412
0.99
0.06
2.4
2.4
24.19
20.15
au/ml
0.28
30
302
11
99
1.11
0.06
1.3
1.1
—
—
—
0
0
26
246
1.06
0.06
2.2
2.6
34.14
30.03
mg/l
0.26
21
169
28
294
0.95
0.06
1.1
1.1
—
—
—
0
0
11
120
0.92
0.05
1.2
1.4
358.45
409.25
mu/l
0.34
11
115
22
209
1.05
0.04
1.2
1.2
10.77
8.75
mm/h
0.43
22
209
430
4272
1.01
0.04
1.9
1.8
—
—
—
0
0
33
318
1.04
0.04
1.2
1.4
168.75
195.66
pmol/l
0.36
33
318
44
451
0.98
0.03
1.3
1.3
6.93
7.04
mmol/l
0.10
39
404
10
92
1.09
0.03
1.4
1.1
—
—
—
0
0
212
2103
1.01
0.03
3.5
3.6
4.55
4.56
pmol/l
0.06
194
1910
137
1383
0.99
0.02
2.4
2.3
—
—
—
0
0
203
2017
1.01
0.02
1.1
1.1
—
—
—
0
0
23
222
1.04
0.02
1.0
1.0
—
—
—
0
0
51
519
0.98
0.02
1.1
1.6
331.27
349.35
mu/l
0.22
44
417
1431
14293
1.00
0.01
3.2
2.9
—
—
—
0
0
52
527
0.99
0.01
1.0
1.1
1.89
2.86
eliau/ml
0.98
19
265
10
94
1.06
0.01
1.8
2.1
14.84
16.42
umol/l
—
10
94
25
244
1.02
0.00
1.0
1.0
0.72
0.82
u/ml
—
10
49
21
208
1.01
0.00
1.6
2.0
1.33
1.60
u/field
0.28
15
122
24
242
0.99
0.00
1.0
1.0
10.70
1.74
u/ml
—
9
69
17
165
1.03
0.00
2.6
2.4
15.46
16.34
%
0.40
17
165
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.9
—
2.63
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
2.90
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.2
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
74.02
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
2334.33
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.03
—
0
7

Mortality – FinRegistry

Association

Association between endpoint ULCERRECT and mortality.

Females

Parameter HR [95% CI] p-value
ULCERRECT 1.163 [1.04, 1.3] 0.008
Birth year 0.996 [0.99, 1.0] 0.309

During the follow-up period (1.1.1998 — 31.12.2019), 677 out of 8056 females with ULCERRECT died.

Males

Parameter HR [95% CI] p-value
ULCERRECT 1.093 [1.0, 1.2] 0.061
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1254 out of 9221 males with ULCERRECT died.

Mortality risk

Mortality risk for people of age

years, who have ULCERRECT.

N-year risk Females Males
1 0.07% 0.233%
5 0.59% 1.167%
10 1.628% 2.921%
15 3.162% 5.473%
20 5.425% 8.891%

Relationships between endpoints

Index endpoint: ULCERRECT – Ulcerative rectosigmoiditis

GWS hits: 18

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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