Ulcerative proctitis

ULCERPROCT

proctitis: An inflammatory process affecting the anus. It is usually caused by sexually transmitted infectious agents and/or inflammatory bowel disease.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K51.2
  • Cause of death: ICD-10 K51.2

2 out of 7 registries used, show all original rules.

2903

4. Check minimum number of events

None

2903

5. Include endpoints

None

2903

6. Filter based on genotype QC (FinnGen only)

2631

Control definitions (FinnGen only)

Control exclude
K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K51
Name in latin
Proctitis ulcerosa [chronica]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13877 7303 6509
Only index persons 13418 7120 6298
Unadjusted period prevalence (%)
Whole population 0.20 0.21 0.18
Only index persons 0.25 0.26 0.24
Median age at first event (years)
Whole population 42.59 40.72 44.56
Only index persons 42.09 40.47 43.93

-FinnGen-

Key figures

All Female Male
Number of individuals 2631 1510 1121
Unadjusted period prevalence (%) 0.53 0.54 0.51
Median age at first event (years) 44.46 40.58 49.69

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2729
Matched controls
27290
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
42.1
317.8
192
49
A07EA06
ATC
budesonide; oral, local oral
300.0
307.7
1253
77
L04AX01
ATC
azathioprine; systemic
43.5
307.7
787
252
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
26.7
307.7
290
121
A07EC01
ATC
sulfasalazine; oral, rectal
7.9
307.7
621
979
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
307.7
315
*
H02AB06
ATC
prednisolone; systemic
5.2
307.7
1952
8866
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
307.7
349
*
K51.8
ICD-10 Finland
Other ulcerative colitis
2920.5
307.7
505
*
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
+∞
307.7
2729
*
UJF30
NOMESCO Finland
Ileoscopy through colon
15.3
307.7
1106
1162
K51.5
ICD-10 Finland
Left sided colitis
6076.7
307.7
1144
*
D94
ICPC
Chronic enteritis/ulcerative colitis
261.1
307.7
302
13
A07EA02
ATC
hydrocortisone; rectal
793.3
307.7
1249
29
K51
ICD-10 Finland
Ulcerative colitis
1236.4
307.7
505
5
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
16384.0
307.7
1099
*
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3357.7
307.7
1253
7
L01BB02
ATC
mercaptopurine; oral
168.9
307.7
366
25
A07EC02
ATC
mesalazine; oral, rectal
3524.9
307.7
2522
94
UJF32
NOMESCO Finland
Coloscopy
18.7
307.7
1984
3408
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
53.2
307.7
193
39
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
15.2
307.7
866
809
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
307.7
2264
*
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
+∞
306.1
288
*
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
48.7
260.9
152
33
A07EA01
ATC
prednisolone; oral, rectal
895.0
253.3
245
*
L04AB02
ATC
infliximab; parenteral
105.0
252.2
130
13
H02AB07
ATC
prednisone; oral
4.9
251.8
676
1717
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.3
187.9
1100
4670
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
6.1
186.1
352
648
K50.9
ICD-10 Finland
Crohn disease, unspecified
643.8
185.0
181
*
K50.8
ICD-10 Finland
Other Crohn disease
+∞
157.9
150
*
L04AC05
ATC
ustekinumab; parenteral
59.9
155.7
87
15
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
231.4
149.7
153
7
K50.1
ICD-10 Finland
Crohn disease of large intestine
1505.2
146.2
141
*
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
127.1
121
*
L04AB04
ATC
adalimumab; parenteral
8.1
126.2
174
227
A06AC01
ATC
ispaghula (psylla seeds); oral
2.7
118.8
859
3924
A07EC03
ATC
olsalazine; oral
+∞
113.3
108
*
D16
ICPC
Rectal bleeding
7.1
110.5
172
257
J01MA02
ATC
ciprofloxacin; systemic
2.4
107.2
1199
6668
ZX120
NOMESCO Finland
Intravenous
3.7
105.7
377
1137
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.5
103.5
894
4406
4AA12, ,
NOMESCO Finland
53.9
101.6
58
11
253, ,
Kela drug reimbursment
+∞
91.1
87
*
K50.0
ICD-10 Finland
Crohn disease of small intestine
+∞
90.1
86
*
3042, ,
Kela drug reimbursment
+∞
90.1
86
*
UJF92
NOMESCO Finland
Capsular endoscopy
8.8
89.3
114
135
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
89.0
85
*
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
23.0
86.6
63
28
C05AA08
ATC
fluocortolone; rectal, topical
2.9
85.3
471
1836
L04AG05
ATC
vedolizumab; parenteral
+∞
83.8
80
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
82.5
710
3440
UJG02
NOMESCO Finland
Proctoscopy
6.9
82.3
130
197
P01AB01
ATC
metronidazole; oral, rectal
2.1
79.9
1249
7717
K92.1
ICD-10 Finland
Melaena
4.4
77.3
203
488
Z93.2
ICD-10 Finland
Ileostomy status
39.0
74.8
46
12
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
72.2
69
*
4AB02, ,
NOMESCO Finland
28.7
71.4
48
17
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
3.8
69.7
225
629
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
+∞
64.8
62
*
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
329.7
64.7
65
*
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
221.9
63.4
65
*
WX002
NOMESCO Finland
Sedation and analgesia
2.3
61.1
548
2665
256, ,
Kela drug reimbursment
+∞
59.6
57
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.0
57.9
103
176
L04AB06
ATC
golimumab; parenteral
9.6
55.2
65
69
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.3
55.0
113
221
L04AA33
ATC
[U] vedolizumab
+∞
53.3
51
*
A07DA03
ATC
loperamide; oral
4.9
52.6
118
249
L04AF03
ATC
upadacitinib; oral
22.0
52.6
39
18
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
52.2
50
*
A07AA09
ATC
vancomycin; oral
8.1
52.1
70
88
JFH10
NOMESCO Finland
Total colectomy and ileostomy
180.1
51.1
53
*
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
+∞
50.2
48
*
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
14.3
49.4
45
32
A02BC02
ATC
pantoprazole; systemic
1.9
49.3
1839
14324
C10AC01
ATC
colestyramine; oral
5.0
48.7
106
218
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
48.4
1095
7318
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
47.2
611
3394
JFF10
NOMESCO Finland
Loop enterostomy
13.6
46.0
43
32
UJF34
NOMESCO Finland
Left colonoscopy
12.8
45.2
44
35
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
12.8
44.4
43
34
UJF30, ,
SPAT
7.9
44.3
61
79
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
+∞
43.9
42
*
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
43.9
42
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
42.7
1179
8268
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.6
40.9
138
396
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.7
39.8
220
844
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
38.9
656
3953
298, ,
Kela drug reimbursment
14.2
38.2
35
25
UJH02
NOMESCO Finland
Anoscopy
3.4
37.9
142
436
D18
ICPC
Change in faeces/bowel movements
4.0
37.2
106
270
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
36.0
267
1179
3029
Kela drug reimbursment
Upadacitinib
12.6
35.8
35
28
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.0
35.5
422
2253
A02BC05
ATC
esomeprazole; systemic
1.7
34.0
1049
7450
TJF80
NOMESCO Finland
Ostomy education
7.4
33.9
49
67
A02BC03
ATC
lansoprazole; oral
1.8
33.4
692
4407
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
+∞
33.4
32
*
JFH11
NOMESCO Finland
Laparoscopic colectomy
+∞
33.4
32
*
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
4.0
32.9
96
249
L04AD01
ATC
ciclosporin; systemic
4.6
32.7
78
173
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
31.6
383
2053
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
+∞
31.3
30
*
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
5.5
31.2
61
114
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
11.1
31.1
33
30
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
31.0
270
1275
A06AC51
ATC
ispaghula, combinations; oral
3.0
31.0
145
508
K61.0
ICD-10 Finland
Anal abscess
4.4
31.0
78
181
WVA20
NOMESCO Finland
Medicine administration
3.6
30.4
100
282
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
30.2
352
1859
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.8
30.0
153
562
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
10.1
29.2
33
33
JHA00
NOMESCO Finland
Anal or perianal incision
4.6
28.1
66
145
K83.0
ICD-10 Finland
Cholangitis
5.7
27.9
52
93
K50
ICD-10 Finland
Crohn disease [regional enteritis]
141.4
26.7
28
*
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.5
26.6
174
724
N02AX02
ATC
tramadol; systemic, rectal
1.6
26.0
1051
7829
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
25.5
590
3837
A02BC01
ATC
omeprazole; systemic
1.6
25.1
648
4334
3AC01, ,
NOMESCO Finland
6.1
25.0
43
71
H02AB09
ATC
hydrocortisone; systemic
3.4
24.1
86
256
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
24.0
23
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.7
23.6
131
503
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
23.5
1159
8956
D11
ICPC
Diarrhoea
1.8
23.0
370
2165
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.3
22.9
171
755
J01DB01
ATC
cefalexin; oral
1.7
22.9
2228
19855
N02BE01
ATC
paracetamol; systemic, rectal
1.8
22.7
2362
21396
K62.6
ICD-10 Finland
Ulcer of anus and rectum
5.0
22.5
48
97
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
22.4
340
1953
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
3.6
21.1
69
194
56902
ICD-8 Finland
Other diseases of intestines and peritoneum, Proctitis haemorrhagica (ulcerosa)
+∞
20.9
20
*
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
20.9
20
*
1370
FHL
Colonoscopy, whole colon
19.6
20.8
31
16
H02AB04
ATC
methylprednisolone; systemic
1.8
20.6
348
2064
D01
ICPC
Abdominal pain/cramps general
1.8
20.4
354
2114
L04AX03
ATC
methotrexate; systemic
1.9
20.3
256
1383
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
20.3
674
4751
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
4.2
20.3
53
127
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
3.5
20.0
70
206
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.1
19.9
84
278
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
+∞
19.8
19
*
4AA33, ,
NOMESCO Finland
+∞
19.8
19
*
D99
ICPC
Disease digestive system other
5.0
19.7
42
85
M45
ICD-10 Finland
Ankylosing spondylitis
3.3
19.4
74
230
JAH00
NOMESCO Finland
Laparotomy
3.2
19.3
75
236
C05AA01
ATC
hydrocortisone; rectal, topical
2.5
18.6
123
515
D06BX01
ATC
metronidazole; topical
1.8
18.3
280
1609
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
18.2
233
1265
Z2221
NOMESCO Finland
Medical doctor
1.5
18.0
682
4926
B01AB05
ATC
enoxaparin; parenteral
1.5
17.9
691
5013
ZXC86
NOMESCO Finland
Use of endoscopic device
7.3
17.8
26
36
J02AC01
ATC
fluconazole; systemic
1.4
17.7
1002
7830
Z01.2
ICD-10 Finland
Dental examination
1.4
17.4
1272
10399
K59.1
ICD-10 Finland
Functional diarrhoea
2.2
17.4
147
685
D04
ICPC
Rectal/anal pain
3.8
17.3
52
138
1490
FHL
Sigmoideoscopy (fiberscope)
24.2
17.3
24
10
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.0
16.9
179
910
JHD00
NOMESCO Finland
Anal dilatation
6.1
16.8
29
48
SPAT1263
SPAT
Sampling
1.4
16.7
1021
8065
A05AA02
ATC
ursodeoxycholic acid; oral
3.4
16.7
60
180
J01MA12
ATC
levofloxacin; systemic
1.6
16.6
405
2644
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
16.5
261
1514
K56.0
ICD-10 Finland
Paralytic ileus
5.6
16.5
31
56
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
16.5
1088
8708
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
18.0
16.5
25
14
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
18.0
16.5
25
14
D07AC01
ATC
betamethasone; topical
1.4
16.3
883
6818
L04AA01
ATC
[U] ciclosporin
4.3
16.2
42
100
A02BA02
ATC
ranitidine; systemic
1.6
16.2
389
2529
K60.3
ICD-10 Finland
Anal fistula
3.3
16.0
60
185
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
15.9
1971
17540
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.1
15.8
153
751
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
15.8
596
4285
K62.7
ICD-10 Finland
Radiation proctitis
6.6
15.7
25
38
A03CA02
ATC
clidinium and psycholeptics; oral
2.3
15.6
113
493
3005
Kela drug reimbursment
Tofacitinib
11.8
15.5
28
24
K52.1
ICD-10 Finland
Toxic gastroenteritis and colitis
160.9
15.5
16
*
Z43.2
ICD-10 Finland
Attention to ileostomy
38.3
15.4
19
5
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
4.1
15.4
41
100
J01FA10
ATC
azithromycin; systemic
1.4
15.0
1525
13047
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.0
15.0
171
892
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
15.0
288
1766
R50.9
ICD-10 Finland
Fever, unspecified
1.6
14.9
384
2534
J05AB01
ATC
aciclovir; systemic
1.5
14.8
543
3875
UKC02
NOMESCO Finland
Cystoscopy
1.7
14.7
309
1939
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
3.6
14.6
48
136
R03AC02
ATC
salbutamol; inhalant
1.4
14.6
1412
11959
N05CF01
ATC
zopiclone; oral
1.4
14.4
698
5260
K62.9
ICD-10 Finland
Disease of anus and rectum, unspecified
5.0
14.3
30
60
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
3.8
14.2
43
115
E0000UV, ,
ATC
1.4
14.1
1036
8377
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.0
13.8
29
58
TPH04, ,
SPAT
4.0
13.8
38
95
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
3.3
13.7
51
157
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
13.7
253
1534
JGB40
NOMESCO Finland
Excision of rectum and end ileostomy
+∞
13.5
13
*
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
2.7
13.4
74
284
B80
ICPC
Iron deficiency anaemia
2.6
13.4
77
302
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.8
13.3
64
229
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
13.2
443
3098
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
13.1
242
1466
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
13.0
430
2998
L04AA29
ATC
[U] tofacitinib
10.1
13.0
25
25
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
12.9
1050
8600
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.0
12.9
149
782
R10.2
ICD-10 Finland
Pelvic and perineal pain
2.5
12.8
77
309
SPAT1131
SPAT
Colonoscopy
2.7
12.8
70
268
L01BA01
ATC
methotrexate; systemic
2.4
12.8
87
370
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
2.3
12.6
92
403
K59.4
ICD-10 Finland
Anal spasm
6.0
12.6
22
37
JG1JB
NOMESCO Finland
Defekography with X-ray
4.6
12.6
29
63
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.3
12.5
95
424
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
12.5
1434
12349
K52.80
ICD-10 Finland
(Hemorrhagic) colitis caused by antibiotics
130.6
12.4
13
*
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.2
12.3
107
505
J31.0
ICD-10 Finland
Chronic rhinitis
1.7
12.3
228
1383
K62.3
ICD-10 Finland
Rectal prolapse
4.0
12.2
34
86
M54.5
ICD-10 Finland
Low back pain
1.4
12.0
936
7589
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
12.0
911
7357
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
12.0
439
3122
R01AD09
ATC
mometasone; nasal
1.3
11.9
1182
9937
UJF32, ,
SPAT
2.3
11.9
88
389
K60.2
ICD-10 Finland
Anal fissure, unspecified
2.9
11.8
54
188
WX892
NOMESCO Finland
Monitored bed care
1.8
11.8
164
915
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
11.7
251
1580
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.5
11.7
70
280
S29
ICPC
Skin symptom/complaint other
1.5
11.7
469
3393
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
11.7
1823
16340
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
3.6
11.6
37
103
K52.0
ICD-10 Finland
Gastroenteritis and colitis due to radiation
+∞
11.5
11
*
SPAT1262
SPAT
Handing over of treatment supplies
1.5
11.5
354
2429
K56.7
ICD-10 Finland
Ileus, unspecified
3.6
11.4
37
104
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
13.7
11.4
19
14
JFF13
NOMESCO Finland
Terminal enterostomy
13.7
11.4
19
14
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
11.3
200
1197
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
11.3
1020
8439
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
17.1
11.2
17
10
N03AX16
ATC
[U] pregabalin
1.4
11.1
489
3601
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.8
11.0
171
986
R51.80
ICD-10 Finland
Headache
1.5
11.0
413
2950
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
11.0
891
7250
SPAT1301
SPAT
No procedures
1.4
11.0
672
5235
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
11.0
770
6129
JFB00
NOMESCO Finland
Partial resection of small intestine
3.6
10.9
35
98
KMAK, ,
NOMESCO Finland
1.3
10.9
1346
11618
R02
ICPC
Shortness of breath/dyspnoea
1.6
10.8
294
1960
JF1BD
NOMESCO Finland
Very extensive small bowel CT
11.9
10.8
19
16
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
3.4
10.8
38
113
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.6
10.8
229
1439
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.3
10.7
81
361
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
10.7
1452
12678
D64.9
ICD-10 Finland
Anaemia, unspecified
1.7
10.7
193
1162
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.0
10.7
118
610
S18
ICPC
Laceration/cut
1.3
10.6
1075
9014
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
10.6
897
7332
R52.9
ICD-10 Finland
Pain, unspecified
1.6
10.6
245
1572
B82
ICPC
Anaemia other/unspecified
2.5
10.5
63
253
SPAT1255
SPAT
Intravenous administration of medicine
1.9
10.5
141
778
JF2AB
NOMESCO Finland
Colongraphy with X-ray
14.2
10.5
17
12
R06.0
ICD-10 Finland
Dyspnoea
1.4
10.4
578
4424
R53
ICD-10 Finland
Malaise and fatigue
1.4
10.4
617
4774
J01CA04
ATC
amoxicillin; systemic
1.4
10.4
2167
20078
XJH00
NOMESCO Finland
Transanal ultrasonography
2.1
10.4
102
506
D07AD01
ATC
clobetasol; topical
1.5
10.3
373
2641
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.4
10.2
499
3735
N03AX12
ATC
[U] gabapentin; oral
1.5
10.2
350
2451
Z3231
NOMESCO Finland
Registered nurse
1.4
10.2
593
4572
J05AB11
ATC
valaciclovir; oral
1.5
10.2
336
2335
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
10.2
1394
12155
J01AA02
ATC
doxycycline; systemic
1.3
10.2
1892
17195
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.1
10.1
97
477
I84.5
ICD-10 Finland
External hemorrhoids without complication
2.4
10.1
69
295
K30
ICD-10 Finland
Functional dyspepsia
1.6
10.1
276
1844
R01AD08
ATC
fluticasone; nasal
1.3
9.9
708
5633
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
9.9
1187
10155
UJF02
NOMESCO Finland
Peroral enteroscopy
7.6
9.9
22
29
WX402
NOMESCO Finland
General anaesthesia
1.4
9.8
540
4123
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
8.8
9.8
20
23
A03BA03
ATC
hyoscyamine; oral
4.5
9.8
23
51
B01AB10
ATC
tinzaparin; parenteral
1.6
9.7
236
1532
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
9.7
1013
8500
M25.5
ICD-10 Finland
Pain in joint
1.3
9.7
827
6748
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
9.7
501
3786
JF1AD
NOMESCO Finland
Small bowel CT
5.3
9.6
19
36
R05
ICPC
Cough
1.4
9.6
596
4639
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.7
9.6
29
78
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.3
9.6
681
5413
UJD02
NOMESCO Finland
Gastroscopy
2.0
9.5
96
481
I84.1
ICD-10 Finland
Internal hemorrhoids with other complications
2.6
9.5
54
212
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.1
9.5
87
421
J01EA01
ATC
trimethoprim; systemic
1.4
9.5
524
4004
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
3.4
9.4
33
98
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.2
9.4
80
375
5589X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis, Other and unspecified non-infectious gastro-enteritis and colitis
+∞
9.4
9
*
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
+∞
9.4
9
*
1380
FHL
Colonoscopy, left side
+∞
9.4
9
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
9.4
307
2130
WZC30
NOMESCO Finland
Teaching
1.5
9.3
363
2606
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
3.2
9.3
36
114
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
9.3
690
5514
JHB96
NOMESCO Finland
Other procedure for haemorrhoids or prolapse of mucosa
4.5
9.3
22
49
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
2.4
9.3
59
244
Z71.8
ICD-10 Finland
Other specified counselling
1.3
9.3
870
7188
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
2.6
9.2
51
197
SXC05
NOMESCO Finland
Other oral or dental procedure
1.7
9.2
168
1016
M13.9
ICD-10 Finland
Arthritis, unspecified
1.7
9.2
172
1047
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
2.6
9.1
52
204
WX704
NOMESCO Finland
Intubation
1.7
9.1
186
1158
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
9.1
798
6530
N06AX11
ATC
mirtazapine; oral
1.3
9.1
793
6485
Z93
ICD-10 Finland
Artificial opening status
15.6
9.0
14
9
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
3.7
9.0
28
77
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.1
9.0
79
376
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
2.7
9.0
47
177
L88
ICPC
Rheumatoid/seropositive arthritis
2.0
9.0
93
471
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.2
9.0
73
337
A29
ICPC
General symptom/complaint other
1.5
8.9
282
1941
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.5
8.9
287
1984
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.2
8.9
23
55
M01AH01
ATC
celecoxib; oral
1.4
8.8
346
2486
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
8.8
214
1391
A02BC04
ATC
rabeprazole; oral
1.6
8.8
205
1319
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
8.8
720
5830
WZA90
NOMESCO Finland
Other medical or dental certificate
1.4
8.8
560
4371
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
14.1
8.7
14
10
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.5
8.7
239
1598
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.5
8.7
287
1995
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.3
8.7
702
5673
M03BX02
ATC
tizanidine; oral
1.3
8.7
1568
14037
E86
ICD-10 Finland
Volume depletion
2.7
8.6
46
175
M05BA04
ATC
alendronic acid; oral
1.8
8.6
128
731
R01AD12
ATC
fluticasone furoate; nasal
1.3
8.4
825
6836
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
+∞
8.3
8
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.6
8.2
177
1117
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.8
8.2
125
718
J01FA09
ATC
clarithromycin; systemic
1.3
8.2
733
5996
M01AH02
ATC
rofecoxib; oral
1.6
8.2
218
1446
K62.2
ICD-10 Finland
Anal prolapse
3.7
8.2
25
68
WX720
NOMESCO Finland
Own respiration
1.8
8.1
112
624
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
8.1
230
1548
R31
ICD-10 Finland
Unspecified haematuria
1.6
8.1
185
1186
SBB10
NOMESCO Finland
Dental impressions
1.6
8.1
169
1060
A01AB09
ATC
miconazole; local oral
1.7
8.0
161
998
A01
ICPC
Pain general/multiple sites
1.5
8.0
222
1486
K52.2
ICD-10 Finland
Allergic and dietetic gastroenteritis and colitis
22.1
8.0
11
5
M05BX04
ATC
denosumab; parenteral
1.9
7.9
98
528
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
7.9
650
5253
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.4
7.9
309
2219
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
7.9
437
3334
SFA10
NOMESCO Finland
One-surface restoration
1.3
7.9
1422
12663
-1, ,
NOMESCO Finland
1.3
7.8
833
6965
E87.6
ICD-10 Finland
Hypokalaemia
2.1
7.8
71
343
A98
ICPC
Health maint/preventive medicine
1.8
7.8
2637
25641
R96
ICPC
Asthma
1.5
7.8
211
1407
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.5
7.8
235
1604
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.6
7.7
176
1126
R06AX27
ATC
desloratadine; oral
1.3
7.7
742
6124
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
4.5
7.6
18
40
G04CA02
ATC
tamsulosin; oral
1.4
7.6
401
3030
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
7.6
468
3624
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.7
7.6
139
841
K02.1
ICD-10 Finland
Caries of dentine
1.3
7.6
1565
14118
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
7.6
180
1163
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.3
7.6
54
236
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
7.6
315
2287
Z71.9
ICD-10 Finland
Counselling, unspecified
1.6
7.5
194
1278
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.5
7.5
217
1466
S21
ICPC
Skin texture symptom/complaint
1.4
7.5
320
2333
ZXE00
NOMESCO Finland
One hour or less
1.3
7.5
869
7337
ZYC01
NOMESCO Finland
Remote contact by phone
1.6
7.5
152
947
J01DA09
ATC
[U] cefadroxil
1.3
7.4
605
4878
SFA20
NOMESCO Finland
Two-surface restoration
1.2
7.4
1523
13717
N05CF02
ATC
zolpidem; oral
1.4
7.4
387
2922
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
1.9
7.4
87
462
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
1.9
7.4
86
455
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
7.3
894
7585
J01DA01
ATC
[U] cefalexin
1.2
7.3
1470
13199
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
+∞
7.3
7
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
1.7
7.3
131
790
N02AJ13
ATC
tramadol and paracetamol; systemic
2.3
7.3
52
228
F29
ICPC
Eye symptom/complaint other
1.5
7.3
237
1643
A06AD11
ATC
lactulose; oral
1.5
7.2
243
1694
D10AX03
ATC
azelaic acid; topical
1.5
7.2
200
1339
K60.1
ICD-10 Finland
Chronic anal fissure
2.2
7.2
59
274
S10
ICPC
Boil/carbuncle
1.7
7.2
139
855
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
7.2
663
5434
K08.80
ICD-10 Finland
Toothache NOS
1.5
7.2
234
1623
JFG96
NOMESCO Finland
Other operation on intestinal stoma or pouch
30.1
7.1
9
*
D06
ICPC
Abdominal pain localized other
1.5
7.1
201
1351
SPAT1254
SPAT
Administration of medicine
1.4
7.1
282
2028
N06AB10
ATC
escitalopram; oral
1.3
7.1
523
4156
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
7.1
309
2263
R06AE07
ATC
cetirizine; oral
1.2
7.0
1071
9311
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
7.0
806
6783
E000002, ,
ATC
1.5
7.0
247
1738
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
7.0
1858
17167
XKD00
NOMESCO Finland
Uroflowmetry
1.4
7.0
260
1849
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.5
6.9
220
1516
K96
ICPC
Haemorrhoids
2.0
6.9
74
381
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.4
6.9
360
2719
F51.0
ICD-10 Finland
Nonorganic insomnia
1.3
6.8
449
3510
L88
ICD-10 Finland
Pyoderma gangrenosum
11.0
6.8
12
11
K07.4
ICD-10 Finland
Malocclusion, unspecified
2.3
6.8
48
210
ZXD05
NOMESCO Finland
Urgent procedure
1.3
6.8
681
5637
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
5.7
6.7
18
32
SDA03
NOMESCO Finland
Periodontal treatment
1.2
6.7
1032
8968
A07AA02
ATC
nystatin; oral
1.8
6.7
105
610
H04.10
ICD-10 Finland
Dry eye syndrome
1.4
6.7
256
1830
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
1.8
6.7
92
514
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
1.9
6.6
80
429
K62.4
ICD-10 Finland
Stenosis of anus and rectum
7.8
6.6
14
18
U05
ICPC
Urination problems other
1.8
6.6
98
561
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.3
6.5
862
7361
J01MA06
ATC
norfloxacin; oral
1.4
6.5
241
1712
A02BA03
ATC
famotidine; systemic
2.1
6.5
58
279
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.2
6.5
53
246
E000001, ,
ATC
1.3
6.5
440
3453
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.0
6.5
69
355
N05BA04
ATC
oxazepam; oral
1.3
6.5
575
4684
R03DC03
ATC
montelukast; oral
1.4
6.4
376
2887
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
1.7
6.4
106
625
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.3
6.4
407
3163
JFA76
NOMESCO Finland
Closure of fistula of small intestine
70.0
6.4
7
*
WW200
NOMESCO Finland
Immunization
2.1
6.4
61
301
D20
ICPC
Mouth/tongue/lip symptom/complaint
1.7
6.4
106
626
K63.3
ICD-10 Finland
Ulcer of intestine
14.3
6.4
10
7
N20.1
ICD-10 Finland
Calculus of ureter
1.9
6.4
77
413
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
6.4
485
3868
M02AA10
ATC
ketoprofen; topical
1.4
6.4
309
2304
A46
ICD-10 Finland
Erysipelas
1.4
6.4
272
1985
L12
ICPC
Hand/finger symptom/complaint
1.3
6.3
400
3108
D19
ICPC
Teeth/gum symptom/complaint
1.3
6.3
773
6542
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.5
6.3
181
1223
D15
ICPC
Melaena
6.0
6.3
16
27
L04AF01
ATC
tofacitinib; oral
11.0
6.3
11
10
JFH00
NOMESCO Finland
Total colectomy and ileorectal anastomosis
9.3
6.3
12
13
D29
ICPC
Digestive symptom/complaint other
2.1
6.3
59
290
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
+∞
6.3
6
*
JFH31
NOMESCO Finland
Laparoscopic total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
+∞
6.3
6
*
M79.6
ICD-10 Finland
Pain in limb
1.2
6.2
1029
8993
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.6
6.2
124
770
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.5
6.2
213
1493
D93
ICPC
Irritable bowel syndrome
2.5
6.2
36
144
R60.9
ICD-10 Finland
Oedema, unspecified
1.7
6.2
105
625
SPAT1058
SPAT
PEF monitoring instruction
1.6
6.2
146
945
0093A
ICD-9 Finland
Ill-defined intestinal infections, Diarrhoea of presumed infectious origin
2.7
6.2
32
121
K03.64
ICD-10 Finland
Dental calculus supragingival
1.2
6.1
834
7138
TKC20
NOMESCO Finland
Catheterisation of bladder
1.7
6.1
114
696
R07.0
ICD-10 Finland
Pain in throat
1.5
6.1
187
1281
R01AD58
ATC
fluticasone, combinations; nasal
1.3
6.1
650
5409
I84.8
ICD-10 Finland
Unspecified hemorrhoids with other complications
4.1
6.1
16
39
D07AC13
ATC
mometasone; topical
1.3
6.1
638
5299
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
12.5
6.1
10
8
K91.8
ICD-10 Finland
Other postprocedural disorders of digestive system, not elsewhere classified
12.5
6.1
10
8
R42
ICD-10 Finland
Dizziness and giddiness
1.3
6.1
449
3566
L01
ICPC
Neck symptom/complaint
1.3
6.1
390
3037
L02AE02
ATC
leuprorelin; implant, parenteral
1.8
6.0
84
472
JHB00
NOMESCO Finland
Hemorrhoidectomy
1.9
6.0
66
343
SFA30
NOMESCO Finland
Three-surface restoration
1.2
6.0
998
8718
N06AX21
ATC
duloxetine; oral
1.4
6.0
269
1979

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1605
2133
16.84
307.65
2.1
1.2
—
—
—
0
0
2101
2808
29.17
307.65
7.5
1.3
214.17
89.63
ug/g
28.37
1988
2167
210
31
73.31
307.65
2.7
2.3
105.02
160.21
au/ml
—
49
9
2091
9340
6.30
307.65
8.4
4.7
37.15
36.27
g/l
13.68
2034
8790
239
31
84.40
307.65
3.5
2.5
9.45
5.59
mg/l
3.90
203
24
2131
12014
4.53
252.21
12.6
6.0
0.04
0.04
e9/l
1.02
1945
10410
2128
11993
4.52
251.77
12.6
6.0
0.56
0.57
e9/l
1.56
1946
10401
2159
12409
4.54
245.43
12.8
6.3
0.19
0.19
e9/l
0.07
1988
10950
2140
12319
4.42
240.26
12.7
6.0
1.92
1.97
e9/l
0.81
1983
10957
2574
17296
9.60
231.79
16.5
7.4
73.05
76.82
u/l
6.67
2538
16493
1978
10987
3.91
229.27
12.9
6.2
8.66
8.63
%
0.18
1920
10358
1974
10960
3.90
228.72
12.7
6.1
2.91
2.83
%
1.01
1916
10326
1966
10965
3.84
224.35
12.9
6.2
0.74
0.68
%
6.68
1907
10325
1900
10411
3.72
221.90
3.9
2.3
75.56
75.07
nmol/l
0.37
1836
9614
1980
11162
3.82
220.61
12.4
6.0
56.14
56.75
%
1.74
1934
10714
1986
11363
3.75
212.81
12.7
6.1
29.38
28.61
%
2.82
1939
10823
2180
13344
4.15
208.46
14.2
9.4
3.89
4.07
e9/l
4.01
1983
11637
1276
5727
3.31
201.31
3.6
2.1
2.49
2.70
mg/l
2.97
1178
4975
2420
17094
4.67
161.85
7.3
4.0
10.21
10.37
mm/h
0.27
2332
16143
97
47
21.36
129.04
2.1
1.3
10.26
8.70
mg/l
1.09
84
38
405
1286
3.52
104.99
1.4
1.2
—
—
—
0
0
681
2928
2.77
104.21
3.8
3.1
4.51
4.88
e9/l
0.31
616
2611
690
3069
2.67
98.06
2.7
2.6
23.04
24.01
%
1.10
658
2873
735
3379
2.61
97.61
2.7
2.5
2.41
2.36
g/l
1.65
697
3150
766
3651
2.53
93.80
2.8
2.5
14.07
13.98
umol/l
0.11
733
3426
731
3412
2.56
93.54
1.6
1.7
—
—
—
0
0
1350
8239
2.26
93.32
4.6
3.2
30.01
33.18
u/l
0.52
1252
7831
485
1886
2.91
88.44
6.1
4.3
0.45
0.71
%
1.82
134
524
1772
12243
2.28
88.41
4.4
3.1
94.50
108.49
ug/l
2.37
1712
11605
486
1935
2.84
84.55
6.9
4.8
0.06
0.30
%
0.72
120
448
492
1981
2.81
83.73
6.7
4.5
0.65
0.94
%
1.49
136
558
477
1903
2.83
82.53
6.8
4.6
0.07
0.10
%
0.70
122
479
1573
10534
2.16
82.37
16.7
10.2
0.00
0.00
e9/l
0.63
1352
8618
1174
7080
2.16
79.99
4.1
2.6
58.69
58.74
u/l
0.01
1117
6611
1677
11662
2.14
77.65
7.1
6.3
10.75
11.19
umol/l
0.78
1626
11133
917
5104
2.20
75.75
1.7
1.7
—
—
—
0
0
209
527
4.21
74.73
1.2
1.3
251.07
252.99
u/ml
0.03
135
327
235
646
3.89
74.62
1.4
1.2
78.26
100.96
titre
0.61
23
73
1381
9280
1.99
66.00
2.5
2.0
—
—
—
0
0
2663
23451
6.61
65.71
26.5
13.4
17.19
22.78
mg/l
22.91
2381
19009
158
374
4.42
61.21
4.2
3.3
3.68
4.11
e9/l
1.92
158
374
257
863
3.18
59.62
1.7
1.7
—
—
—
0
0
265
965
2.93
53.21
1.2
1.2
—
—
—
0
0
173
485
3.74
53.13
4.4
3.1
55.37
57.94
%
1.65
173
485
858
5267
1.92
50.00
1.6
1.4
2.36
2.32
g/l
0.21
577
3419
641
3559
2.05
49.95
1.5
1.4
518.34
490.14
titre
0.16
145
714
147
400
3.83
47.08
1.1
1.2
—
—
—
0
0
325
1411
2.48
45.89
1.9
1.9
1.21
1.36
g/l
0.95
306
1320
1039
6939
1.80
45.26
8.5
6.0
—
—
—
0
0
388
1843
2.29
44.64
2.4
2.9
10.94
10.53
g/l
1.34
366
1716
1434
10635
1.73
42.42
7.5
7.1
1.22
1.21
mmol/l
2.56
1266
9231
920
6071
1.78
40.73
1.4
1.3
1.01
1.67
u/ml
1.62
219
1743
947
6302
1.77
40.73
2.0
2.1
—
—
—
0
0
1297
9473
1.70
39.55
2.2
2.0
97.39
96.74
pmol/l
0.20
740
5198
178
614
3.03
39.15
1.4
1.1
—
—
—
0
0
395
1991
2.15
38.95
3.1
2.2
0.23
0.22
g/l
4.76
369
1862
545
3139
1.92
36.92
2.0
1.6
1062.14
1189.20
nmol/l
2.56
384
2460
1287
9497
1.67
36.84
13.1
12.3
1.16
1.19
inr
1.88
1098
7878
2678
24897
5.05
35.29
30.1
16.6
75.30
74.89
umol/l
0.34
2669
24640
2564
23280
2.68
34.69
21.2
15.3
139.60
139.67
mmol/l
0.78
2524
22837
842
5630
1.72
34.36
4.6
4.2
—
—
—
0
0
1597
12600
1.64
34.04
4.2
3.6
0.01
0.13
estimate
0.50
359
2451
1270
9482
1.63
33.66
6.6
6.5
1.21
1.21
mmol/l
1.65
1195
8821
2668
24817
4.36
33.48
22.1
10.6
26.02
26.93
u/l
1.89
2655
24259
1588
12547
1.64
33.33
4.1
3.5
12.88
5.98
estimate
0.52
370
2618
2563
23347
2.61
32.94
21.4
15.4
3.92
3.95
mmol/l
8.35
2520
22851
1318
10051
1.60
31.17
3.6
3.2
6.09
6.20
ph
4.02
796
5803
1559
12413
1.60
30.41
4.1
3.5
0.00
0.00
estimate
0.80
356
2585
898
6320
1.63
29.06
4.3
4.2
7.39
7.40
ph
0.46
685
4472
452
2644
1.85
28.51
3.1
2.8
5.76
7.41
umol/l
1.92
404
2320
73
172
4.33
28.43
1.2
1.1
161.82
144.62
titre
0.09
22
26
667
4385
1.69
28.00
2.2
1.6
101320549.43
42175490.71
pmol/l
0.90
606
3770
1804
15047
1.59
27.36
5.2
4.2
2446.52
1421.15
e6/l
0.17
25
202
119
400
3.07
27.35
1.8
1.6
0.64
0.83
g/l
1.36
93
316
2286
20273
1.79
26.95
28.7
16.6
13.54
13.44
%
3.39
2279
20020
840
5909
1.61
26.78
1.7
1.6
20.41
20.06
nmol/l
0.30
754
5161
497
3059
1.76
26.29
1.2
1.2
—
—
—
0
0
172
723
2.47
25.71
1.2
1.3
—
—
—
0
0
1619
13292
1.54
25.33
5.4
5.0
6.47
6.57
mmol/l
1.23
1521
12475
399
2333
1.83
24.97
1.5
1.5
—
—
—
0
0
383
2220
1.84
24.63
3.0
2.4
52.38
59.62
u/l
0.12
337
1872
808
5770
1.57
23.56
4.8
4.0
93.56
92.23
%
0.84
785
5665
91
301
3.09
21.53
4.0
3.7
0.91
1.48
%
1.46
81
281
1203
9564
1.46
20.11
4.1
3.4
0.02
0.04
estimate
0.61
314
2157
626
4377
1.56
19.43
1.3
1.3
3.85
10.56
u/ml
4.51
226
1814
824
6132
1.49
19.02
3.1
2.8
—
—
—
0
0
206
1063
2.01
18.62
1.1
1.1
—
—
—
0
0
928
7102
1.46
18.48
3.5
3.0
0.02
0.06
estimate
0.90
323
2084
753
5533
1.50
18.38
3.9
3.6
1.02
1.58
kg/l
0.80
506
3617
184
920
2.07
18.13
1.5
1.6
6.68
18.71
iu/ml
0.85
11
23
342
2104
1.72
17.64
1.2
1.2
—
—
—
0
0
661
4766
1.51
17.55
1.3
1.3
18.71
26.31
iu/ml
2.03
195
1408
162
788
2.12
17.16
1.4
1.2
—
—
—
0
0
90
337
2.73
17.07
1.1
1.1
1.50
1.48
g/l
0.28
84
306
357
2245
1.68
16.95
2.6
2.8
1.72
1.77
%
0.39
323
2029
60
184
3.31
16.14
3.8
3.3
52.92
55.83
%
0.48
52
167
125
565
2.27
15.89
3.0
2.9
1.75
1.92
index
0.13
73
311
2689
25928
3.53
15.89
37.1
20.7
6.75
6.72
e9/l
0.22
2675
25441
895
6963
1.42
15.72
3.0
2.7
0.10
0.02
—
10
107
2688
25923
3.46
15.67
37.1
20.6
4.50
4.56
e12/l
7.43
2675
25445
2687
25908
3.41
15.66
37.2
20.7
266.24
254.78
e9/l
16.03
2677
25491
363
2383
1.60
14.42
2.4
2.1
343.41
382.06
nmol/l
3.26
336
2229
1312
11036
1.36
13.90
3.2
2.7
—
—
estimate
—
0
0
51
158
3.27
13.55
1.1
1.1
1490.08
1541.31
miu/ml
0.11
51
158
852
6725
1.39
13.26
4.3
3.7
0.00
0.00
estimate
1.94
355
2431
454
3199
1.50
13.05
2.0
2.1
—
—
—
0
0
1041
8522
1.36
12.78
4.3
3.7
76.01
83.74
e6/l
0.12
774
5804
901
7229
1.37
12.52
3.6
3.2
38.08
77.36
e6/l
1.67
723
5421
267
1681
1.65
12.50
2.6
2.8
70.77
71.34
e9/l
0.09
201
1219
296
1913
1.61
12.48
3.3
4.3
16.00
21.17
ug/l
0.20
212
1524
135
699
1.98
12.12
3.7
3.5
72.38
2231.18
u/ml
0.88
118
602
549
4099
1.42
11.56
3.7
3.6
540.95
466.60
ng/l
0.13
359
2854
1927
17440
1.36
11.47
4.1
3.2
44.25
42.94
u/l
0.29
1850
16680
111
549
2.07
11.33
1.3
1.5
—
—
—
0
0
411
2923
1.48
11.17
1.5
1.5
—
—
—
0
0
781
6221
1.36
11.08
3.5
3.1
0.31
0.39
e6/l
0.47
602
4458
156
876
1.83
10.97
1.5
1.9
1.57
1.48
g/l
0.56
138
767
288
1910
1.57
10.85
4.4
3.6
—
—
—
0
0
37
108
3.46
10.84
1.4
1.7
3736.00
3520.00
titre
0.06
15
13
386
2747
1.47
10.42
1.8
1.7
—
—
—
0
0
631
4908
1.37
10.30
2.8
2.6
4.82
6.23
e6/l
2.81
586
4444
50
182
2.78
10.13
1.0
1.1
—
—
—
0
0
299
2032
1.53
10.08
4.1
3.8
1.90
1.80
mmol/l
0.15
253
1754
686
5424
1.35
10.05
1.9
1.8
1.01
1.02
mg/l
0.05
547
4078
307
2104
1.52
9.95
4.3
3.7
7.37
7.38
ph
1.39
177
1208
118
630
1.91
9.74
4.8
5.5
1.27
1.29
mmol/l
0.05
111
549
963
8051
1.30
9.43
3.7
3.3
58.27
56.52
ng/l
0.03
574
4980
303
2098
1.50
9.34
4.1
3.7
5.90
5.83
kpa
0.78
294
2035
2327
21924
1.42
9.28
5.6
5.2
1.66
1.83
mu/l
13.86
2226
20670
112
598
1.91
9.26
1.5
1.4
289.03
296.88
ug/g
0.14
66
344
233
1537
1.56
8.98
4.1
4.1
83.68
85.67
ng/l
0.12
210
1382
543
4205
1.36
8.97
3.0
2.8
533.29
540.37
mosm/kgh2o
0.31
488
3673
59
252
2.37
8.69
1.4
1.3
—
—
—
0
0
47
181
2.62
8.60
4.7
4.0
—
—
—
0
0
97
507
1.95
8.56
1.4
1.5
161.01
155.17
au/ml
0.14
19
140
59
254
2.35
8.54
1.4
1.3
2.86
3.03
g/l
0.37
43
188
59
254
2.35
8.54
1.4
1.3
0.31
0.38
g/l
1.45
42
186
897
7507
1.29
8.51
3.3
3.3
2.35
2.35
mmol/l
0.24
817
6938
59
255
2.34
8.47
1.4
1.3
7.00
6.62
g/l
0.34
43
188
499
3849
1.36
8.41
3.2
2.7
0.77
1.08
e6/l
1.21
283
1962
903
7576
1.29
8.37
2.7
2.3
—
—
—
0
0
476
3655
1.37
8.24
4.3
3.6
0.80
0.82
mmol/l
3.50
439
3479
464
3564
1.36
8.00
3.4
2.9
2.76
2.56
e6/l
0.18
246
1682
261
1811
1.49
7.96
1.4
1.3
162.18
200.66
u/ml
0.39
245
1679
120
692
1.77
7.80
1.1
1.1
1.13
4.44
eliau/ml
—
9
109
381
2847
1.39
7.77
5.9
6.3
1.02
1.04
mmol/l
0.70
360
2656
688
5682
1.28
6.99
2.7
2.3
—
—
—
0
0
17
28
6.10
6.76
2.1
2.1
—
—
—
0
0
151
976
1.58
6.41
2.6
2.3
—
—
—
0
0
119
725
1.67
6.41
2.9
3.8
1.31
1.43
mg/l
1.17
110
675
38
154
2.49
6.35
1.8
1.6
—
—
—
0
0
80
437
1.86
6.28
1.0
1.1
—
—
—
0
0
203
1411
1.47
6.16
3.1
2.8
214.20
168.08
ng/l
0.52
181
1278
125
781
1.63
6.12
1.7
1.8
1.19
1.19
g/l
0.01
118
742
1999
18743
1.25
6.03
4.7
4.4
14.66
14.56
pmol/l
1.12
1897
17517
80
443
1.83
6.03
1.0
1.1
—
—
—
0
0
259
1892
1.41
6.02
4.2
3.9
7.36
7.35
ph
0.29
207
1380
158
1055
1.53
5.83
1.9
2.0
6.65
7.32
iu/ml
0.14
42
269
242
1757
1.41
5.83
3.5
3.1
4.46
4.68
kpa
0.65
232
1702
155
1031
1.53
5.82
1.3
1.3
0.22
0.98
u/ml
—
9
81
143
937
1.56
5.75
1.3
1.2
—
—
—
0
0
145
962
1.54
5.53
1.6
1.7
6.38
13.18
u/ml
1.88
27
258
12
17
7.08
5.43
1.1
1.0
—
—
—
0
0
250
1849
1.39
5.42
9.1
10.0
—
—
—
0
0
109
681
1.63
5.38
2.5
2.5
—
—
—
0
0
118
756
1.59
5.26
1.7
1.9
0.23
0.23
g/l
0.56
111
717
280
2126
1.35
5.15
1.9
2.0
0.04
0.02
estimate
0.22
57
494
61
327
1.89
5.14
1.8
1.4
63.82
64.71
mmol/l
0.05
39
275
245
1824
1.38
5.11
2.8
2.2
5.94
6.11
ph
2.12
160
1180
57
301
1.91
5.03
3.5
2.6
6.45
97.11
u/ml
0.98
57
296
118
765
1.57
5.01
1.4
2.3
3.78
3.72
g/l
0.15
109
709
37
166
2.25
5.01
2.1
2.8
245.90
216.94
e6/l
0.27
29
145
118
766
1.56
4.99
1.4
2.2
4.28
4.24
g/l
0.19
109
708
27
105
2.59
4.97
1.7
3.1
125.13
146.89
umol/l
0.15
16
57
13
24
5.44
4.91
1.8
1.5
—
—
—
0
0
258
1963
1.35
4.70
7.7
8.4
1.28
1.34
mmol/l
0.41
252
1918
24
92
2.62
4.56
1.2
5.3
87.78
66.96
mg/l
0.59
18
68
765
6655
1.21
4.55
2.3
2.2
254.06
216.87
u/l
0.15
732
6357
307
2407
1.31
4.54
7.9
8.7
5.04
5.12
kpa
0.70
296
2317
41
200
2.07
4.54
2.1
2.3
41.63
38.26
%
0.65
41
200
307
2408
1.31
4.53
7.8
8.7
12.71
12.64
kpa
0.08
296
2319
8
8
10.02
4.52
1.1
1.0
—
—
—
0
0
103
664
1.57
4.52
1.3
2.3
10.60
10.51
g/l
0.05
92
603
304
2402
1.30
4.26
8.1
8.7
7.41
7.41
ph
0.10
176
1309
28
120
2.35
4.25
2.8
3.2
0.79
0.79
index
0.02
28
120
20
73
2.75
4.18
3.6
3.0
0.61
0.62
mmol/l
0.46
20
73
301
2384
1.30
4.14
7.9
8.6
0.72
0.92
mmol/l
0.38
252
1955
273
2138
1.31
4.09
8.5
9.1
96.06
95.76
%
0.34
267
2071
485
4076
1.23
4.03
2.6
2.7
2.44
2.43
mmol/l
0.11
418
3662
7
7
10.02
4.01
1.3
1.6
—
—
—
0
0
7
7
10.02
4.01
1.0
1.0
229.14
307.86
u/ml
—
7
7
107
720
1.51
3.91
1.3
1.3
19.01
8.74
u/ml
0.63
15
106
245
1908
1.31
3.83
7.8
8.2
9.23
8.92
mmol/l
0.29
235
1847
33
159
2.09
3.82
2.5
2.7
488.52
529.39
e6/l
0.17
25
131
40
207
1.95
3.82
1.3
1.1
—
—
—
0
0
106
716
1.50
3.81
1.3
1.3
3.65
7.01
u/ml
0.31
11
65
37
187
1.99
3.78
1.2
1.3
327911.00
92791.02
e6/l
0.43
21
129
237
1842
1.31
3.76
1.4
1.4
—
—
—
0
0
226
1746
1.32
3.75
2.5
2.5
0.20
0.42
e6/l
1.96
217
1658
686
6010
1.19
3.67
2.7
2.6
330.92
335.51
umol/l
0.59
617
5420
26
118
2.21
3.51
1.3
1.2
26.28
36.81
mmol/l
2.95
19
110
194
1484
1.33
3.46
2.3
2.3
5240.43
6679.35
u/l
0.26
80
609
10
22
4.56
3.43
1.1
1.1
—
—
—
0
0
40
216
1.86
3.40
2.4
2.6
1318.91
1228.79
e6/l
0.28
32
192
148
1093
1.37
3.33
3.2
2.8
1.17
1.29
%
0.76
148
1086
788
7035
1.17
3.32
3.5
3.2
0.60
0.73
—
5
22
7
225
0.31
3.31
7.4
21.2
1557.71
1432.53
nmol/l
—
7
219
34
176
1.94
3.29
3.1
3.1
13.11
13.38
index
0.07
28
120
1678
15845
1.15
3.24
3.9
3.6
0.50
13291.74
—
6
31
89
603
1.49
3.21
1.2
1.2
20.90
48.46
u/ml
—
7
57
36
192
1.89
3.20
1.4
1.1
—
—
—
0
0
7
219
0.32
3.18
6.7
16.0
941.14
821.00
nmol/l
—
7
212
33
172
1.93
3.14
1.2
1.1
377.11
410.94
nmol/l
0.41
27
160
107
757
1.43
3.10
1.5
1.3
—
—
—
0
0
145
1081
1.36
3.10
3.2
2.8
0.68
0.62
%
1.43
145
1076
132
970
1.38
3.08
2.0
1.8
—
—
—
0
0
28
139
2.02
3.05
2.1
2.7
534.82
958.56
u/ml
1.08
28
139
31
160
1.95
3.04
1.1
1.5
4.60
8.72
ug/l
1.93
25
139
135
1001
1.37
2.99
3.2
3.1
1.02
1.02
ratio
0.21
122
903
67
434
1.56
2.99
2.6
3.8
2.55
2.39
mmol/l
0.22
42
272
625
5520
1.17
2.98
3.1
3.1
1544.92
1110.73
ng/l
1.04
534
4641
732
6548
1.16
2.96
5.5
5.0
3.26
2.11
ug/l
0.47
672
5964
48
287
1.68
2.95
1.4
1.3
—
—
—
0
0
36
198
1.83
2.93
1.1
1.2
—
—
—
0
0
2245
21731
1.19
2.93
6.0
5.6
38.23
38.38
mmol/mol
0.31
2141
20687
39
221
1.78
2.89
1.6
1.6
54.43
54.66
%
0.01
21
141
36
199
1.82
2.89
1.0
1.1
9.58
10.26
iu/ml
—
10
62
2402
23403
1.22
2.88
4.8
4.7
4.64
4.69
mmol/l
1.72
2310
22301
391
3330
1.20
2.83
2.5
2.2
29.17
29.47
s
0.49
379
3237
147
1118
1.33
2.78
1.9
2.1
0.02
0.66
estimate
0.49
48
385
21
97
2.17
2.77
3.1
2.5
—
—
—
0
0
78
534
1.47
2.72
1.6
1.7
8742.32
12757.48
e6/l
0.77
56
375
2283
22170
1.18
2.67
4.8
4.5
5.78
5.82
mmol/l
0.81
2154
20754
28
147
1.91
2.65
1.5
1.3
5.57
7.12
u/l
0.63
23
126
2419
23622
1.21
2.61
5.3
5.2
2.72
2.79
mmol/l
3.56
2305
22412
86
609
1.43
2.54
2.5
3.7
41.11
44.47
mg/l
0.14
78
517
86
609
1.43
2.54
2.5
3.7
41.62
58.16
mg/l
0.84
78
518
749
6781
1.14
2.51
4.2
4.3
9.19
8.80
mg/mmol
0.07
491
4397
738
6680
1.14
2.48
3.6
3.6
45.79
49.84
mg/l
0.20
488
4405
836
7633
1.14
2.46
3.4
3.5
7.87
8.04
mmol/l
0.46
737
6639
93
673
1.40
2.44
1.9
2.1
11.69
11.14
mg/l
0.29
88
636
67
457
1.48
2.42
2.8
2.3
6.94
6.72
umol/l
0.04
51
333
96
700
1.38
2.42
1.1
1.1
—
—
—
0
0
18
83
2.18
2.41
2.7
2.7
—
—
—
0
0
203
1646
1.25
2.39
2.2
2.7
67.35
66.87
g/l
0.38
190
1532
158
1244
1.29
2.37
1.4
1.8
0.27
0.30
mg/l
0.34
70
606
2387
23316
1.19
2.36
4.7
4.6
1.46
1.44
mmol/l
0.94
2282
22095
210
1713
1.24
2.35
1.5
1.4
24.99
24.03
iu/l
0.15
178
1458
830
7596
1.13
2.34
1.6
1.6
—
—
—
0
0
41
252
1.64
2.33
1.4
1.6
273.45
281.97
mosm/kgh2o
1.58
31
189
428
3742
1.17
2.31
1.6
1.5
—
—
—
0
0
16
73
2.20
2.21
1.8
2.2
0.37
0.14
e9/l
—
7
35
60
410
1.47
2.18
1.4
1.3
3.50
4.55
u/ml
0.39
28
193
70
493
1.43
2.17
2.1
2.4
133.61
131.50
g/l
0.31
56
395
31
182
1.71
2.11
1.4
1.5
26.51
35.60
%
0.45
13
119
194
1592
1.24
2.08
2.1
2.2
4.55
7.93
ug/l
4.47
167
1447
170
1375
1.25
2.08
3.0
3.6
5.04
5.16
kpa
1.35
164
1327
75
540
1.40
2.07
2.5
3.5
1.73
3.15
ratio
0.84
51
296
1070
10008
1.11
2.03
1.9
1.9
1.37
1.38
mmol/l
0.06
928
8689
99
750
1.33
2.01
1.9
1.9
205.88
207.08
pmol/l
0.03
99
708
29
170
1.71
2.00
2.6
2.7
0.80
0.67
e9/l
0.77
29
165
160
1292
1.25
2.00
1.9
2.4
—
—
—
0
0
87
647
1.36
1.99
1.1
1.1
—
—
—
0
0
58
402
1.45
1.98
2.1
1.6
—
—
—
0
0
106
815
1.31
1.95
1.9
2.0
17.96
1.67
ug/l
0.60
91
730
352
3073
1.17
1.95
1.4
1.3
—
—
—
0
0
19
98
1.95
1.95
1.1
1.1
—
—
—
0
0
200
1660
1.22
1.95
3.6
3.6
1.23
1.23
mmol/l
0.10
184
1437
28
164
1.71
1.94
1.4
1.2
—
77.42
—
0
10
30
181
1.66
1.88
1.1
1.1
—
—
—
0
0
120
949
1.28
1.81
2.1
2.1
21.50
20.73
s
0.30
102
841
38
247
1.55
1.78
1.1
1.1
—
—
—
0
0
58
412
1.42
1.77
1.2
1.2
—
—
—
0
0
15
74
2.03
1.75
2.8
2.0
35.99
57.99
ug/l
1.84
15
74
271
3126
0.85
1.74
1.3
1.3
—
—
—
0
0
269
2321
1.18
1.74
2.5
2.3
12.63
13.10
nmol/l
0.40
247
2126
5
13
3.85
1.71
2.4
1.8
—
—
—
0
0
27
163
1.66
1.71
1.1
1.1
1.06
1.05
ratio
0.22
18
131
21
118
1.79
1.70
1.1
1.1
16.35
12.91
u/ml
0.22
12
82
43
291
1.49
1.70
2.3
2.4
—
—
—
0
0
28
174
1.62
1.60
1.3
1.2
—
—
—
0
0
161
1337
1.22
1.60
3.0
3.6
7.42
7.41
ph
0.81
142
1134
63
465
1.36
1.57
3.0
3.7
—
—
—
0
0
197
1674
1.19
1.55
1.3
1.2
—
—
—
0
0
76
579
1.32
1.55
1.1
1.1
—
—
—
0
0
5
15
3.34
1.52
2.4
2.1
—
—
—
0
0
5
15
3.34
1.52
1.4
1.2
—
—
—
0
0
53
383
1.39
1.51
1.4
1.3
—
8.28
—
0
8
138
1138
1.22
1.49
1.3
1.3
208.83
224.69
miu/ml
0.17
54
551
35
235
1.50
1.47
1.2
1.1
17.66
15.15
u/ml
0.19
16
103
54
395
1.37
1.44
1.0
1.1
1.09
2.80
eliau/ml
2.87
20
197
25
156
1.61
1.43
2.0
2.8
36.84
42.89
%
0.79
12
79
13
66
1.97
1.43
1.6
1.6
—
—
—
0
0
75
580
1.30
1.40
1.1
1.1
—
—
—
0
0
68
522
1.31
1.35
3.0
3.1
8.50
8.36
kpa
0.27
68
511
9
42
2.15
1.33
5.3
2.9
4.56
5.35
ug/l
—
9
42
64
489
1.32
1.32
2.1
1.9
—
—
—
0
0
26
168
1.55
1.31
1.0
1.0
—
—
—
0
0
18
106
1.70
1.29
2.7
1.7
137.68
105.94
ng/l
0.42
18
106
16
93
1.72
1.21
4.9
5.1
—
—
—
0
0
43
316
1.37
1.16
1.7
1.6
—
—
—
0
0
1008
10571
0.93
1.16
2.8
2.8
—
—
—
0
0
6
128
0.47
1.16
2.5
2.2
141.67
148.37
nmol/l
—
6
115
56
429
1.31
1.16
1.2
1.2
—
—
—
0
0
420
3847
1.11
1.16
1.9
1.8
—
—
—
0
0
35
249
1.41
1.14
2.7
2.6
—
—
—
0
0
41
300
1.37
1.14
2.7
2.3
—
—
—
0
0
37
268
1.39
1.10
1.2
1.4
—
—
nmol/l
—
0
0
186
1633
1.15
1.04
3.8
3.7
4.54
4.58
pmol/l
0.21
170
1479
109
1291
0.84
1.04
1.1
1.1
1.48
1.52
g/l
1.04
109
1291
15
90
1.67
1.04
1.1
1.5
72.47
97.96
nmol/24h
0.84
15
90
42
316
1.33
1.01
1.7
1.6
—
—
—
0
0
42
316
1.33
1.01
1.7
1.6
—
—
—
0
0
42
316
1.33
1.01
1.7
1.6
—
—
—
0
0
37
273
1.36
1.01
4.0
3.4
0.77
0.83
nmol/l
0.26
31
223
22
147
1.50
1.00
1.8
2.2
1.82
1.60
u/field
0.12
11
91
9
48
1.88
1.00
1.2
1.2
—
—
—
0
0
2248
22124
1.09
0.99
4.0
4.0
1.27
1.29
mmol/l
0.32
2141
20832
0
29
0.00
0.97
0.0
1.2
—
742.29
—
0
7
0
29
0.00
0.97
0.0
1.0
—
83.86
—
0
29
7
36
1.95
0.97
1.6
2.0
—
—
—
0
0
56
444
1.27
0.94
1.3
1.2
—
—
—
0
0
14
85
1.65
0.94
1.1
1.0
—
—
—
0
0
16
101
1.59
0.93
1.6
1.7
—
—
—
0
0
27
192
1.41
0.92
1.4
1.3
152.90
213.64
pmol/l
0.59
27
192
105
1228
0.85
0.90
1.1
1.1
0.66
0.64
ratio
0.13
13
128
97
1142
0.84
0.90
1.5
1.5
56.44
59.26
ug/l
0.24
75
949
11
63
1.75
0.90
1.0
1.1
23.35
41.85
iu/ml
0.74
11
63
74
891
0.83
0.88
1.5
1.5
—
—
—
0
0
6
30
2.00
0.87
5.5
7.0
0.13
0.19
%
—
6
30
21
299
0.70
0.86
1.0
1.3
—
—
—
0
0
109
936
1.17
0.86
2.6
3.7
—
—
—
0
0
152
1339
1.14
0.85
11.0
11.5
0.59
0.64
%
0.91
152
1331
43
335
1.29
0.84
1.3
1.7
—
—
—
0
0
6
32
1.88
0.81
1.0
1.1
0.02
0.02
u/ml
—
6
32
6
32
1.88
0.81
1.8
1.7
—
—
—
0
0
15
97
1.55
0.81
1.1
1.1
18.57
268.00
ng/l
—
7
21
26
189
1.38
0.81
1.5
2.4
—
—
—
0
0
236
2592
0.90
0.80
1.4
1.7
3.40
3.50
mmol/l
0.63
146
1736
62
510
1.22
0.79
1.1
1.1
24.93
14.83
au/ml
0.42
26
147
32
242
1.33
0.78
4.4
5.4
72.51
72.17
u/ml
—
10
78
74
879
0.84
0.78
1.5
1.5
1.22
1.27
mm
0.61
52
621
14
90
1.56
0.78
1.4
1.2
29.71
29.02
s
0.13
14
90
57
466
1.23
0.77
1.3
1.4
24.16
22.71
u/l
0.12
49
390
18
124
1.45
0.75
1.2
1.1
—
—
—
0
0
54
441
1.23
0.74
4.8
3.4
25.32
25.85
mg/l
0.04
40
298
21
150
1.40
0.73
1.3
1.2
—
—
—
0
0
52
426
1.22
0.71
3.4
3.0
90.51
90.29
%
0.10
52
412
5
26
1.92
0.70
2.6
2.7
0.40
0.85
u/field
—
5
26
16
110
1.46
0.68
1.5
1.6
—
—
—
0
0
16
226
0.71
0.66
1.4
1.1
—
—
—
0
0
18
128
1.41
0.65
1.2
1.6
0.49
0.51
e9/l
0.08
18
128
10
62
1.62
0.65
1.1
1.0
—
—
—
0
0
15
103
1.46
0.65
4.7
3.3
—
—
—
0
0
15
103
1.46
0.65
1.3
1.1
—
—
—
0
0
16
112
1.43
0.63
1.6
1.8
1.82
4.92
u/field
0.95
11
87
79
912
0.86
0.63
1.6
1.5
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.5
—
30.06
—
0
20
8
51
1.57
0.60
1.9
1.4
3.14
3.17
mmol/l
—
8
44
11
72
1.53
0.59
1.3
1.3
—
—
—
0
0
113
1008
1.13
0.58
2.0
1.9
—
—
—
0
0
52
437
1.19
0.58
4.2
4.0
—
—
—
0
0
24
184
1.31
0.57
1.3
1.2
—
—
—
0
0
6
35
1.72
0.57
2.5
3.3
—
—
—
0
0
26
202
1.29
0.57
1.1
1.2
0.56
0.63
ratio
0.75
17
121
33
267
1.24
0.54
4.3
2.2
1.16
0.89
%
1.15
27
177
29
231
1.26
0.53
1.4
1.3
2.21
1.00
u/ml
0.25
18
123
6
39
1.54
0.53
1.5
1.1
—
—
—
0
0
139
1264
1.11
0.53
11.6
11.2
23.69
24.35
mmol/l
1.49
133
1243
87
770
1.13
0.52
2.1
2.4
201.11
297.81
ug/l
1.57
82
728
25
197
1.27
0.51
1.2
1.2
—
—
—
0
0
36
297
1.21
0.50
2.4
2.2
—
—
—
0
0
50
426
1.18
0.50
1.3
1.6
336.71
357.63
mu/l
0.25
41
346
12
84
1.43
0.49
1.8
2.3
26.75
30.25
%
0.48
12
84
12
84
1.43
0.49
1.1
1.1
—
—
—
0
0
194
1800
1.08
0.49
2.3
2.4
23.74
20.80
au/ml
0.15
22
220
7
45
1.56
0.49
1.1
2.6
—
—
—
0
0
327
3451
0.94
0.48
1.7
1.9
3.48
3.53
ratio
0.25
236
2585
84
749
1.13
0.47
2.8
3.7
24.80
24.80
mmol/l
0.00
78
693
7
48
1.46
0.46
1.1
1.1
—
—
—
0
0
110
997
1.11
0.46
1.4
1.4
8.64
8.99
u/l
0.14
88
812
5
84
0.59
0.45
1.4
1.6
12.10
15.19
pmol/l
—
5
73
44
375
1.18
0.45
1.2
1.2
—
—
—
0
0
122
1118
1.10
0.42
1.8
3.0
—
—
—
0
0
8
56
1.43
0.42
1.3
1.1
—
—
—
0
0
23
284
0.81
0.42
1.1
1.5
—
—
—
0
0
5
33
1.52
0.41
2.2
3.2
—
—
—
0
0
32
268
1.20
0.41
1.3
1.4
0.16
0.24
nmol/l
0.55
27
207
0
17
0.00
0.40
0.0
8.1
—
180.18
—
0
11
24
195
1.23
0.40
1.0
1.0
11.14
1.98
u/ml
—
8
61
23
188
1.23
0.37
1.1
1.0
—
—
—
0
0
55
620
0.88
0.37
1.1
1.2
3.72
3.73
mmol/l
0.03
50
587
51
449
1.14
0.37
1.2
1.1
38.33
1251.89
iu/ml
—
9
108
31
262
1.19
0.37
1.2
1.1
—
—
—
0
0
9
70
1.29
0.36
1.4
1.1
—
—
—
0
0
154
1439
1.07
0.36
1.1
1.1
—
—
—
0
0
6
43
1.40
0.35
1.0
1.2
—
—
—
0
0
6
43
1.40
0.35
1.0
1.2
—
—
—
0
0
6
43
1.40
0.35
1.0
1.2
—
—
—
0
0
141
1316
1.08
0.34
1.8
1.7
283.92
291.67
mu/l
0.13
131
1199
14
178
0.79
0.34
1.3
1.4
4296.00
68017.99
e6/l
—
5
102
15
118
1.27
0.33
1.2
1.1
255.16
183.04
iu/ml
0.27
15
118
416
4014
1.04
0.33
3.1
3.1
0.67
0.72
ug/l
0.63
269
2402
15
119
1.26
0.31
1.3
1.2
—
—
—
0
0
7
99
0.71
0.30
3.3
3.1
47.43
45.95
%
—
7
99
7
99
0.71
0.30
6.6
6.2
9.57
8.23
%
—
7
99
132
1237
1.07
0.30
1.6
2.1
—
—
—
0
0
29
249
1.17
0.30
1.1
1.4
—
—
—
0
0
15
184
0.81
0.28
1.4
1.5
—
—
—
0
0
176
1671
1.06
0.28
1.3
1.3
70.73
49.83
au/ml
0.62
11
111
84
778
1.08
0.27
3.8
3.4
377.53
365.54
mg/l
0.03
38
351
8
65
1.23
0.27
2.1
1.5
8.15
10.04
mmol/l
—
8
65
13
104
1.25
0.26
1.2
1.1
—
0.07
g/l
—
0
7
8
67
1.19
0.26
1.4
1.1
—
—
—
0
0
51
560
0.91
0.25
1.4
1.3
—
—
—
0
0
32
283
1.13
0.24
1.4
1.6
7.76
7.58
mmol/l
0.19
32
271
16
191
0.84
0.24
1.0
1.0
0.50
2.33
u/ml
—
5
37
16
133
1.20
0.24
1.0
1.0
732.60
739.57
ng/l
—
10
89
14
168
0.83
0.22
1.1
1.1
—
—
—
0
0
58
627
0.92
0.21
1.2
1.4
348.53
1421.62
e6/l
1.22
49
493
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.01
—
0
5
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
16
135
1.19
0.21
1.0
1.0
223.36
273.24
ng/l
0.71
11
92
29
258
1.13
0.21
2.4
2.3
31.69
32.41
pg
0.25
29
258
57
527
1.08
0.21
1.4
2.5
0.87
0.89
nmol/l
0.05
50
456
22
192
1.15
0.20
1.3
1.1
—
—
—
0
0
57
615
0.93
0.20
1.1
1.3
185.48
34.26
e6/l
0.38
48
458
10
123
0.81
0.20
3.4
2.2
10.27
8.18
mmol/l
—
10
123
13
108
1.20
0.20
1.5
1.7
—
—
—
0
0
6
50
1.20
0.19
1.2
1.2
0.02
0.41
u/ml
—
6
50
15
175
0.86
0.18
1.3
1.4
—
—
—
0
0
59
551
1.07
0.18
1.1
1.1
1.62
3.92
u/ml
2.38
27
267
69
733
0.94
0.17
2.8
2.2
2.70
3.81
iu/l
1.77
32
328
192
1985
0.96
0.17
1.6
1.6
1090.78
1014.62
mu/l
0.47
156
1646
19
167
1.14
0.16
1.9
1.4
87.16
76.83
umol/l
0.46
19
167
44
473
0.93
0.16
2.6
2.6
103.38
127.25
ug/min
0.13
22
298
13
111
1.17
0.15
2.1
2.5
27.33
297.28
ug/l
0.66
13
101
40
371
1.08
0.15
1.3
1.4
7.03
7.12
mmol/l
0.07
32
332
62
654
0.95
0.13
1.7
2.8
—
—
—
0
0
54
511
1.06
0.12
1.0
1.1
5.99
4.64
u/ml
0.13
20
222
10
116
0.86
0.12
1.4
1.1
—
—
—
0
0
65
621
1.05
0.11
1.1
1.1
1.25
1.72
u/ml
0.29
32
295
159
1550
1.03
0.10
1.6
2.1
—
—
—
0
0
161
1572
1.03
0.10
1.6
2.1
—
—
—
0
0
5
44
1.14
0.10
7.4
6.0
5.54
5.41
kpa
—
5
44
55
574
0.96
0.09
1.1
1.3
—
—
—
0
0
75
724
1.04
0.09
1.1
1.1
1.82
2.20
u/ml
0.22
37
376
18
196
0.92
0.09
1.7
2.4
50.44
31.36
mg/l
0.78
13
135
133
1298
1.03
0.09
1.5
1.5
—
—
—
0
0
166
1626
1.02
0.08
1.6
1.7
—
—
—
0
0
19
175
1.09
0.08
1.4
1.9
5.74
6.33
mmol/l
1.16
12
122
13
144
0.90
0.08
1.2
1.4
138.38
134.41
nmol/l
0.28
13
144
149
1458
1.02
0.08
1.6
2.2
—
—
—
0
0
11
123
0.89
0.08
1.5
2.6
1716.82
2054.74
ml
1.25
11
111
17
156
1.09
0.08
1.1
1.3
8.18
8.99
mm/h
0.13
17
156
8
74
1.08
0.07
1.5
1.9
41.74
40.86
g/l
—
8
74
161
1580
1.02
0.07
1.6
2.1
—
—
—
0
0
8
76
1.05
0.07
1.5
2.2
18.70
16.22
umol/l
—
8
76
7
85
0.82
0.07
1.3
1.6
0.00
0.04
estimate
—
7
85
9
86
1.05
0.07
1.3
1.5
—
—
—
0
0
20
214
0.93
0.07
1.4
1.4
3868.79
1765.76
e6/l
0.74
14
148
8
92
0.87
0.06
2.1
1.7
—
—
—
0
0
21
197
1.07
0.06
1.2
1.1
120.10
111.06
pmol/l
0.30
21
197
54
557
0.97
0.05
1.4
1.5
76.91
152.10
pmol/l
1.31
54
545
159
1566
1.02
0.05
1.6
2.1
—
—
—
0
0
16
149
1.07
0.05
2.3
2.6
658.67
624.37
ml
—
9
102
47
484
0.97
0.04
1.0
1.0
0.39
0.28
u/ml
0.15
15
149
22
209
1.05
0.04
2.8
2.6
—
—
—
0
0
24
250
0.96
0.03
3.1
2.5
1.90
1.50
g/24h
0.32
17
151
61
622
0.98
0.03
1.1
1.1
0.61
1.30
u/ml
0.79
26
260
64
651
0.98
0.02
1.1
1.1
8.04
5.16
u/ml
0.52
30
351
254
2525
1.01
0.02
4.5
4.4
32.24
31.71
%
0.32
175
1776
18
172
1.05
0.02
1.3
1.8
3.96
3.90
mg/l
0.02
18
167
22
213
1.03
0.01
1.2
1.2
—
—
—
0
0
71
702
1.01
0.01
11.8
8.6
—
—
—
0
0
11
115
0.96
0.00
1.2
1.4
133.55
168.46
mmol/24h
1.27
11
115
11
115
0.96
0.00
4.2
2.5
13.76
16.36
%
1.30
11
115
58
575
1.01
0.00
1.4
1.5
0.38
0.42
nmol/l
0.19
48
463
19
194
0.98
0.00
1.0
1.0
0.44
0.84
u/ml
—
7
40
14
142
0.99
0.00
1.3
1.8
—
—
—
0
0
29
287
1.01
0.00
7.0
6.4
11.32
11.18
mg/l
0.06
29
269
8
80
1.00
-0.00
2.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.02
—
0
6
203
2030
1.00
-0.00
1.3
1.2
69.78
147.04
u/ml
5.69
74
787
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
2.92
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
70.60
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
118.60
—
0
5
5
49
1.02
-0.00
1.0
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
8525.20
—
0
5
18
180
1.00
-0.00
1.4
1.6
—
—
—
0
0
6
69
0.87
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
72.60
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
3.37
—
0
6
6
69
0.87
-0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
1.6
1.3
62.28
66.35
mu/l
—
5
38
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
74
0.95
-0.00
1.6
2.5
—
—
—
0
0
6
69
0.87
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
2280.00
—
0
5

Mortality – FinRegistry

Association

Association between endpoint ULCERPROCT and mortality.

Females

Parameter HR [95% CI] p-value
ULCERPROCT 1.073 [0.94, 1.23] 0.305
Birth year 0.992 [0.98, 1.0] 0.067

During the follow-up period (1.1.1998 — 31.12.2019), 443 out of 6386 females with ULCERPROCT died.

Males

Parameter HR [95% CI] p-value
ULCERPROCT 1.054 [0.94, 1.18] 0.354
Birth year 0.987 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 674 out of 5681 males with ULCERPROCT died.

Mortality risk

Mortality risk for people of age

years, who have ULCERPROCT.

N-year risk Females Males
1 0.095% 0.217%
5 0.556% 1.228%
10 1.432% 3.08%
15 2.668% 5.909%
20 4.512% 9.884%

Relationships between endpoints

Index endpoint: ULCERPROCT – Ulcerative proctitis

GWS hits: 10

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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