ovarian dysfunction: The inability of the ovaries to function.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly females |
313377 |
2. Check conditionsNone |
313377 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
3345 |
4. Check minimum number of eventsNone |
3345 |
5. Include endpoints |
3978 |
6. Filter based on genotype QC (FinnGen only) |
3430 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E20-E35
- Name in latin
- Dysfunctio ovarialis
Similar endpoints
↥List of similar endpoints to
Ovarian dysfunction
based on the number of shared cases.
Similar with more cases:
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 17415 | 17415 | - |
| Only index persons | 16983 | 16983 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.50 | 0.50 | - |
| Only index persons | 0.62 | 0.62 | - |
| Median age at first event (years) | |||
| Whole population | - | 28.41 | - |
| Only index persons | - | 28.30 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3430 | 3430 | - |
| Unadjusted period prevalence (%) | 1.22 | 1.22 | - |
| Median age at first event (years) | 29.98 | 29.98 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3681
- Matched controls
- 36810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
336.9
307.7
2538
241
N97.0
ICD-10 Finland
Female infertility associated with anovulation
20.1
307.7
1011
680
A10BA02
ATC
metformin; oral
6.0
307.7
1385
3344
G03DB01
ATC
dydrogesterone; oral
6.2
307.7
1602
4051
E28.3
ICD-10 Finland
Primary ovarian failure
245.2
307.7
433
20
N91.1
ICD-10 Finland
Secondary amenorrhoea
9.3
307.7
589
740
121
Kela drug reimbursment
Severe hypofunction of sexual glands
31.7
307.7
560
207
L68.0
ICD-10 Finland
Hirsutism
15.6
300.4
266
183
L02BG04
ATC
letrozole; oral
4.4
233.8
691
1854
N97.9
ICD-10 Finland
Female infertility, unspecified
3.9
230.5
825
2541
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
4.7
169.4
430
1014
G03GA01
ATC
chorionic gonadotrophin; parenteral
4.0
160.2
507
1411
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
11.5
157.6
166
151
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.5
153.9
2146
13269
E66.01
ICD-10 Finland
Obesity due to excess calories
3.0
152.4
812
3138
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
4.2
147.5
424
1097
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.7
137.6
950
4191
2564A
ICD-9 Finland
Ovarian dysfunction, Polycystic ovaries
+∞
123.6
118
*
G03FB08
ATC
dydrogesterone and estrogen; systemic
4.1
120.9
356
934
G03GB02
ATC
clomifene; oral
6.1
117.6
209
357
E28.8
ICD-10 Finland
Other ovarian dysfunction
171.0
111.0
116
7
E22.1
ICD-10 Finland
Hyperprolactinaemia
35.9
106.9
67
19
C03DA01
ATC
spironolactone; oral
3.6
98.7
351
1046
N91.2
ICD-10 Finland
Amenorrhoea, unspecified
6.9
93.9
148
223
E66.8
ICD-10 Finland
Other obesity
3.1
92.5
436
1544
G03GA05
ATC
follitropin alfa; parenteral
3.1
91.6
411
1414
G03DA02
ATC
medroxyprogesterone; systemic
3.3
88.5
353
1130
G03GA06
ATC
follitropin beta; parenteral
4.0
86.6
263
702
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
2.8
84.4
488
1928
G03GA02
ATC
human menopausal gonadotrophin; parenteral
3.5
83.2
305
925
TLW00
NOMESCO Finland
Insemination
3.8
82.1
269
757
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.9
80.1
1532
9866
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
3.3
79.0
320
1033
G03FB06
ATC
medroxyprogesterone and estrogen; systemic
4.0
78.8
232
605
G03DA04
ATC
progesterone; systemic, rectal, vaginal
4.0
77.0
232
615
X05
ICPC
Menstruation absent/scanty
4.1
76.9
223
575
N91.5
ICD-10 Finland
Oligomenorrhoea, unspecified
6.9
76.4
120
180
N91.3
ICD-10 Finland
Primary oligomenorrhoea
16.0
73.6
63
40
T90
ICPC
Diabetes non-insulin dependent
2.5
72.6
506
2184
G03HB01
ATC
cyproterone and estrogen; oral
2.1
70.9
877
4808
25690
ICD-8 Finland
Ovarian dysfunction, Syndroma Stein-Leventhal
+∞
70.0
67
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.6
68.8
451
1888
E66.00
ICD-10 Finland
Metabolic syndrome
3.5
68.1
246
737
25610
ICD-8 Finland
Ovarian dysfunction, Hypofunction
+∞
65.8
63
*
Z31.2
ICD-10 Finland
In vitrofertilization
5.4
64.6
130
249
E28.9
ICD-10 Finland
Ovarian dysfunction, unspecified
134.4
62.0
66
5
N91.0
ICD-10 Finland
Primary amenorrhoea
12.1
60.9
61
51
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.3
59.8
541
2608
103
Kela drug reimbursment
Diabetes, insulin-treated
2.2
59.5
545
2640
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.2
59.1
619
3163
E66.9
ICD-10 Finland
Obesity, unspecified
3.0
58.7
268
925
N97.8
ICD-10 Finland
Female infertility of other origin
3.2
58.5
248
820
H01CC01
ATC
ganirelix; parenteral
2.8
58.3
321
1228
H02AB09
ATC
hydrocortisone; systemic
5.5
57.8
112
207
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
2.2
54.3
502
2436
E28.1
ICD-10 Finland
Ovarian dysfunction: Androgen excess
535.7
53.7
53
*
TLW12
NOMESCO Finland
Insertion of frozen embryo
3.3
51.9
209
669
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.4
51.7
197
610
LCA06
NOMESCO Finland
Biopsy of endometrium
2.0
48.7
582
3108
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.4
48.6
184
567
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.8
47.6
860
5263
T82
ICPC
Obesity
2.6
45.4
285
1161
E28.0
ICD-10 Finland
Ovarian dysfunction: Estrogen excess
+∞
44.9
43
*
N98.1
ICD-10 Finland
Hyperstimulation of ovaries
5.5
44.6
87
162
H03AA01
ATC
levothyroxine sodium; systemic
1.8
43.4
904
5749
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
43.2
794
4866
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.0
43.1
561
3077
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
3.7
43.1
138
381
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
41.7
40
*
A10BK03
ATC
empagliflozin; oral
2.8
41.2
213
786
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
41.0
791
4911
G47.3
ICD-10 Finland
Sleep apnoea
1.9
40.2
561
3145
A10BJ06
ATC
semaglutide; parenteral
3.1
39.9
174
584
Z31.1
ICD-10 Finland
Artificial insemination
5.1
39.5
84
169
N97.4
ICD-10 Finland
Female infertility associated with male factors
2.9
38.8
194
703
G03DC02
ATC
norethisterone; oral
2.2
38.5
346
1649
E66
ICD-10 Finland
Obesity
2.2
38.5
339
1603
1413
FHL
Laparoscopy and other therapeutic procedure
4.1
38.2
105
260
LA2HE
NOMESCO Finland
Repeated measurement of ovarian cyst
4.1
36.9
101
249
N02AX02
ATC
tramadol; systemic, rectal
1.6
35.6
1172
8323
H01AC01
ATC
somatropin; parenteral
+∞
35.5
34
*
G03GA04
ATC
urofollitropin; parenteral
6.0
35.1
62
105
Z31.3
ICD-10 Finland
Other assisted fertilization methods
5.4
34.9
69
130
JAH01
NOMESCO Finland
Laparoscopy
2.4
34.5
251
1093
A02BC02
ATC
pantoprazole; systemic
1.5
34.4
2141
17471
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
34.4
1404
10454
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.3
33.6
278
1280
H02AA02
ATC
fludrocortisone; oral
11.8
33.4
34
29
G03FB05
ATC
norethisterone and estrogen; systemic
2.3
33.4
269
1224
L02AE01
ATC
buserelin; implant, nasal, parenteral
4.0
32.6
94
241
8201
FHL
Ovarian preservation exploration and related procedures, eg resection, enucleation or ovariolysis
5.5
32.2
62
114
XLA10, ,
NOMESCO Finland
2.5
32.2
208
857
LBF00
NOMESCO Finland
Perfusion of Fallopian tube
6.4
32.0
53
84
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
2.1
31.7
307
1504
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
31.6
216
914
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
31.3
30
*
B01AB05
ATC
enoxaparin; parenteral
1.6
30.7
838
5651
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.7
30.2
710
4609
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
30.2
471
2722
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.6
30.1
942
6562
R4190
NOMESCO Finland
Nutritional therapy
2.6
30.1
184
739
W15
ICPC
Infertility/subfertility female
3.3
30.0
113
347
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.9
29.3
430
2437
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
29.2
28
*
E89.4
ICD-10 Finland
Postprocedural ovarian failure
11.6
29.1
30
26
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
29.1
621
3925
C07AB07
ATC
bisoprolol; oral
1.6
28.1
891
6209
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
27.6
948
6722
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
27.5
754
5075
SPAT1262
SPAT
Handing over of treatment supplies
1.9
27.3
394
2218
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
273.0
26.7
27
*
N06AX16
ATC
venlafaxine; oral
1.6
26.4
658
4320
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.7
26.4
554
3479
UJF32
NOMESCO Finland
Coloscopy
1.7
26.4
585
3728
J02AC01
ATC
fluconazole; systemic
1.5
26.3
1816
14786
TLW20
NOMESCO Finland
Medical ovulation induction
7.2
26.3
39
55
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.7
25.5
484
2954
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
25.5
1592
12695
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
5.9
25.2
45
77
E28
ICD-10 Finland
Ovarian dysfunction
35.9
25.2
32
9
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
7.4
25.0
36
49
1410
FHL
Laparoscopy
3.3
25.0
94
289
LA2JE
NOMESCO Finland
Follow-up of menstrual cycle with repeated measurement of ovarian cyst
4.4
24.8
61
139
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.7
24.7
474
2902
62800
ICD-8 Finland
Sterility, female, Sterilitas primaria
6.8
24.6
38
56
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.4
24.5
170
724
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.6
24.5
673
4518
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.4
24.2
172
740
A10BJ02
ATC
liraglutide; parenteral
3.0
24.2
105
352
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
8.1
23.9
32
40
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
23.8
581
3785
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
23.8
1067
7955
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
3.0
23.4
104
353
Z31.6
ICD-10 Finland
General counselling and advice on procreation
2.9
23.4
108
375
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
23.3
223
1087
N06AX21
ATC
duloxetine; oral
1.7
23.3
466
2884
M79.7
ICD-10 Finland
Fibromyalgia
2.2
23.1
190
872
25691, ,
ICD-8 Finland
+∞
22.9
22
*
R51.80
ICD-10 Finland
Headache
1.5
22.7
800
5667
N05AH04
ATC
quetiapine; oral
1.5
22.6
763
5357
SPAT1301
SPAT
No procedures
1.5
22.4
1058
7954
N03AX12
ATC
[U] gabapentin; oral
1.7
21.9
438
2707
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
21.9
398
2396
A02BC05
ATC
esomeprazole; systemic
1.4
21.8
1178
9071
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
221.3
21.6
22
*
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
3.8
21.3
65
174
H01CA02
ATC
nafarelin; nasal
2.1
21.3
198
954
G03FB09
ATC
levonorgestrel and estrogen; systemic
4.2
21.1
55
131
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.5
21.0
694
4842
SPAT1263
SPAT
Sampling
1.4
20.9
1617
13236
OAB50, ,
SPAT
2.1
20.4
204
1010
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.7
20.3
364
2182
H02AB06
ATC
prednisolone; systemic
1.4
20.2
1428
11492
N06AB04
ATC
citalopram; systemic
1.5
20.2
679
4751
G03FA01
ATC
norethisterone and estrogen; systemic
1.8
20.1
305
1739
B02AA02
ATC
tranexamic acid; systemic
1.5
20.1
670
4678
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.8
20.0
349
2074
L17
ICPC
Foot/toe symptom/complaint
1.4
20.0
1007
7630
C08CA01
ATC
amlodipine; oral
1.6
20.0
517
3407
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
+∞
19.8
19
*
25699
ICD-8 Finland
Ovarian dysfunction, Other and unspecified
+∞
19.8
19
*
A10AC01
ATC
insulin (human); parenteral
2.0
19.7
235
1240
N91
ICD-10 Finland
Absent, scanty and rare menstruation
4.7
19.6
45
97
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.9
19.6
258
1408
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
19.6
300
1717
6280A
ICD-9 Finland
Infertility, female, Associated with anovulation[STERILITAS ET INFERTILITAS ANOVULATORIA PRIM]
19.5
19.5
29
15
R03AC02
ATC
salbutamol; inhalant
1.4
19.1
2090
17991
OAB72
NOMESCO Finland
Weight control and weight loss guidance
3.3
19.1
73
227
M54.5
ICD-10 Finland
Low back pain
1.4
19.0
1389
11205
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.9
19.0
240
1291
X07
ICPC
Menstruation irregular/frequent
2.2
18.8
165
777
C03CA01
ATC
furosemide; systemic
1.8
18.8
312
1828
SPAT1310
SPAT
Counselling related to known health issue
1.4
18.8
1179
9270
25698
ICD-8 Finland
Ovarian dysfunction, Alia definita
+∞
18.8
18
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
18.8
1347
10830
E03.89
ICD-10 Finland
Other specified hypothyroidism
2.3
18.6
147
663
N03AX16
ATC
[U] pregabalin
1.5
18.4
571
3920
205
Kela drug reimbursment
Chronic hypertension
1.9
18.3
234
1265
A10BH01
ATC
sitagliptin; oral
2.3
18.2
133
580
A02BC03
ATC
lansoprazole; oral
1.5
18.2
657
4657
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
18.1
709
5107
C09CA06
ATC
candesartan; oral
1.5
18.1
644
4551
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
18.1
214
1127
E66.0
ICD-10 Finland
Obesity due to excess calories
4.8
18.0
40
84
E, ,
ICD-9 Finland
7.6
17.8
25
33
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
17.8
274
1569
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
17.8
327
1972
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
17.6
703
5078
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.7
17.5
355
2199
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
17.3
2795
25415
TLW10
NOMESCO Finland
Transfer of fresh embryo
2.2
17.3
144
665
J01DB01
ATC
cefalexin; oral
1.5
17.2
3023
27888
A10BK01
ATC
dapagliflozin; oral
2.3
17.2
133
595
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
17.0
903
6876
N97.1
ICD-10 Finland
Female infertility of tubal origin
2.9
16.9
78
271
B03BA03
ATC
hydroxocobalamin; parenteral
2.4
16.8
111
463
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.7
16.6
1179
14417
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
16.6
777
5781
SPAT1153
SPAT
Removal of sutures
1.4
16.5
748
5529
N02BE01
ATC
paracetamol; systemic, rectal
1.5
16.5
3130
29133
LCA30
NOMESCO Finland
Transfer of oocyte or embryo to uterus in assisted fertilisation
5.1
16.5
34
67
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
16.4
1272
10294
L03
ICPC
Low back symptom/complaint
1.4
16.4
1154
9199
R02
ICPC
Shortness of breath/dyspnoea
1.6
16.3
405
2636
WX725
NOMESCO Finland
Noninvasive ventilation
2.0
16.3
174
883
R53
ICD-10 Finland
Malaise and fatigue
1.4
16.3
1010
7887
J01MA02
ATC
ciprofloxacin; systemic
1.4
16.2
961
7445
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
2.8
16.2
82
300
A12AA04
ATC
calcium carbonate; oral
6.5
16.2
26
40
G03DB02
ATC
megestrol; oral
2.9
16.2
75
262
A02BC01
ATC
omeprazole; systemic
1.4
16.1
804
6046
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
16.1
397
2581
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
16.0
677
4940
R06.0
ICD-10 Finland
Dyspnoea
1.4
15.8
707
5212
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.2
15.7
126
573
P01AB01
ATC
metronidazole; oral, rectal
1.3
15.6
1465
12176
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
15.6
733
5447
WX704
NOMESCO Finland
Intubation
1.8
15.5
259
1519
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.6
15.5
425
2832
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
15.3
1249
10159
M79.6
ICD-10 Finland
Pain in limb
1.3
15.3
1521
12737
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
3.3
15.3
57
175
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
0.6
15.3
279
4451
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.7
15.1
324
2033
N06AX12
ATC
bupropion; oral
1.6
15.1
407
2700
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
15.1
699
5180
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
15.1
312
1941
N85.0
ICD-10 Finland
Endometrial glandular hyperplasia
3.0
15.0
66
224
8113
FHL
Fractional scraping
2.6
15.0
87
342
N02AA05
ATC
oxycodone; systemic
1.7
15.0
257
1520
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
14.9
615
4458
C10AA07
ATC
rosuvastatin; oral
1.5
14.9
573
4099
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.7
14.7
255
1511
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
14.7
1568
13240
T83
ICPC
Overweight
2.2
14.5
125
585
N06AX11
ATC
mirtazapine; oral
1.3
14.4
1123
9053
A10AE04
ATC
insulin glargine; parenteral
1.8
14.4
202
1125
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.7
14.3
291
1802
N06AB10
ATC
escitalopram; oral
1.4
14.3
985
7793
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
14.3
2005
17557
B81
ICPC
Anaemia vit B12/folate deficiency
2.7
14.2
74
275
N06AB06
ATC
sertraline; oral
1.5
14.2
524
3713
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
14.1
461
3190
C10AA05
ATC
atorvastatin; oral
1.5
14.0
524
3727
UKC02
NOMESCO Finland
Cystoscopy
1.8
13.9
218
1255
A10BG03
ATC
pioglitazone; oral
4.1
13.9
37
90
H01
ICPC
Ear pain/earache
1.4
13.9
586
4264
LAA97
NOMESCO Finland
Other laparoscopic puncture of ovary
53.5
13.8
16
*
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
53.5
13.8
16
*
E21.0
ICD-10 Finland
Primary hyperparathyroidism
23.8
13.8
19
8
C08CA05
ATC
nifedipine; systemic
2.1
13.8
129
625
SPAT1260
SPAT
Consultation of another employee
1.5
13.7
561
4058
J01FF01
ATC
clindamycin; systemic
1.4
13.6
777
5956
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.4
13.6
93
395
N05BA04
ATC
oxazepam; oral
1.4
13.6
895
7021
G02CB03
ATC
cabergoline; oral
3.8
13.6
40
105
P06
ICPC
Sleep disturbance
1.5
13.6
553
3996
106
Kela drug reimbursment
Hypoparathyroidism
+∞
13.5
13
*
301
Kela drug reimbursment
Growth hormone
+∞
13.5
13
*
L02AE02
ATC
leuprorelin; implant, parenteral
2.3
13.5
106
478
E34.35
ICD-10 Finland
Abnormal growth retardation
140.5
13.5
14
*
M01AE02
ATC
naproxen; oral, rectal
1.3
13.4
2158
19168
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.2
13.4
107
486
N06AB03
ATC
fluoxetine; oral
1.5
13.4
429
2953
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
2.9
13.4
60
206
6289A
ICD-9 Finland
Infertility, female, Of unspecified origin[STERILITAS ET INFERTILITAS MULIERIS NUD PRIM]
4.3
13.4
34
80
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
2.1
13.3
121
579
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.5
13.3
459
3208
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
13.3
795
6138
N03AE01
ATC
clonazepam; systemic
2.0
13.2
141
717
C07AB02
ATC
metoprolol; systemic
1.6
13.1
311
2000
P76
ICPC
Depressive disorder
1.5
13.1
387
2617
G03FA12
ATC
medroxyprogesterone and estrogen; systemic
2.2
13.1
109
504
SPAT1283
SPAT
Restricted health certificate
1.3
13.1
1113
9064
S18
ICPC
Laceration/cut
1.3
13.1
1236
10217
LAC21
NOMESCO Finland
Laparoscopic destruction of lesion of ovary
2.6
13.0
74
288
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
13.0
1156
9468
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
13.0
645
4824
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.9
12.9
151
793
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
12.9
361
2415
M79.1
ICD-10 Finland
Myalgia
1.4
12.8
626
4671
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
2.0
12.8
144
746
L02AE03
ATC
goserelin; implant
3.3
12.7
48
149
WX002
NOMESCO Finland
Sedation and analgesia
1.5
12.6
410
2831
G03HA01
ATC
cyproterone; systemic
12.3
12.6
22
18
E27.2
ICD-10 Finland
Addisonian crisis
+∞
12.5
12
*
E27.0
ICD-10 Finland
Other adrenocortical overactivity
+∞
12.5
12
*
L15
ICPC
Knee symptom/complaint
1.4
12.5
755
5833
Q96.0
ICD-10 Finland
Karyotype 45,X
130.4
12.4
13
*
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.6
12.4
276
1747
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
12.4
543
3974
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
12.3
304
1974
L68.9
ICD-10 Finland
Hypertrichosis, unspecified
11.6
12.3
22
19
ACC51
NOMESCO Finland
Release of median nerve
1.7
12.3
216
1286
C09CA01
ATC
losartan; oral
1.5
12.3
362
2447
A10AB05
ATC
insulin aspart; parenteral
1.8
12.3
181
1024
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
12.3
152
814
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
12.2
201
1176
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
12.2
454
3222
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.3
12.1
90
397
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
12.1
275
1750
M02AA07
ATC
piroxicam; topical
1.4
12.1
743
5753
G43.9
ICD-10 Finland
Migraine, unspecified
1.5
12.1
413
2881
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
12.0
181
1031
D01
ICPC
Abdominal pain/cramps general
1.4
12.0
586
4369
SFA20
NOMESCO Finland
Two-surface restoration
1.3
12.0
2229
20031
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
12.0
157
857
J01FA06
ATC
roxithromycin; oral
1.3
12.0
1155
9548
C09AA05
ATC
ramipril; oral
1.6
11.9
250
1560
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
11.9
1402
11892
D07AC01
ATC
betamethasone; topical
1.3
11.9
1095
8994
W12
ICPC
Contraception intrauterine
0.7
11.9
524
6999
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
11.8
585
4368
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.8
11.8
186
1073
N04BC06
ATC
cabergoline; oral
5.9
11.8
21
36
G44.2
ICD-10 Finland
Tension-type headache
1.4
11.8
599
4496
LCD00
NOMESCO Finland
Hysterectomy
2.1
11.7
104
494
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.5
11.7
424
2990
N83.1
ICD-10 Finland
Corpus luteum cyst
2.3
11.7
86
378
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
1.7
11.7
229
1405
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
3.2
11.6
46
147
LAE10
NOMESCO Finland
Unilateral oophorectomy
5.5
11.6
22
40
R11
ICD-10 Finland
Nausea and vomiting
1.5
11.6
349
2368
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
11.6
1275
10713
WVA20, ,
SPAT
2.1
11.5
108
525
EBA00
NOMESCO Finland
Extraction of tooth
1.3
11.5
1358
11512
6146A
ICD-9 Finland
Inflammatory disease of ovary, Fallopian tube, pelvic cellular tissue and peritoneum, Pelvic peritoneal adhesions, female
4.3
11.5
29
68
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.3
11.5
827
6555
E23.03
ICD-10 Finland
Lack of ACTH
120.4
11.4
12
*
102
Kela drug reimbursment
Diabetes insipidus
120.4
11.4
12
*
M25.5
ICD-10 Finland
Pain in joint
1.3
11.4
1170
9734
R42
ICD-10 Finland
Dizziness and giddiness
1.4
11.4
611
4623
R52.9
ICD-10 Finland
Pain, unspecified
1.5
11.3
333
2251
SGB10
NOMESCO Finland
Root filling of tooth with one root canal
1.5
11.3
356
2441
N03AX09
ATC
lamotrigine; oral
1.6
11.3
247
1559
A01
ICPC
Pain general/multiple sites
1.5
11.3
308
2048
W85
ICPC
Gestational diabetes
1.5
11.2
389
2719
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
4.3
11.2
28
65
IHZ05, ,
SPAT
1.5
11.2
315
2107
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
11.2
154
854
SGA01
NOMESCO Finland
Emergency treatment
1.4
11.2
657
5046
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
11.1
2528
23176
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.5
11.1
304
2021
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.5
11.1
336
2283
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
1.9
11.1
134
712
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
8.0
11.1
24
30
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
11.1
464
3364
WZC00, ,
SPAT
1.4
11.0
558
4180
SPAT1240
SPAT
Therapeutic discussion
1.4
11.0
582
4392
N06AB05
ATC
paroxetine; oral
1.7
11.0
204
1234
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.6
11.0
230
1436
R96
ICPC
Asthma
1.5
10.9
306
2046
R05
ICPC
Cough
1.3
10.9
941
7644
C09AA02
ATC
enalapril; systemic
1.7
10.9
218
1345
A10BD07
ATC
metformin and sitagliptin; systemic
2.8
10.9
54
197
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
2.0
10.8
113
571
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.0
10.8
108
537
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
2.3
10.8
83
372
C10AA01
ATC
simvastatin; oral
1.5
10.8
349
2404
N92.5
ICD-10 Finland
Other specified irregular menstruation
1.5
10.8
312
2099
TPH04, ,
SPAT
3.4
10.8
38
113
ULC02
NOMESCO Finland
Hysteroscopy
1.7
10.8
182
1072
M01AH05
ATC
etoricoxib; oral
1.3
10.8
1945
17306
OAB72, ,
SPAT
2.2
10.8
90
418
E23.05
ICD-10 Finland
Lack of TSH
12.9
10.6
18
14
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
60.2
10.6
12
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.5
10.6
309
2083
Z31.4
ICD-10 Finland
Procreative investigation and testing
2.3
10.6
82
369
R03DC03
ATC
montelukast; oral
1.4
10.6
594
4524
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
3.5
10.6
35
100
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
1.7
10.6
185
1101
J01CA08
ATC
pivmecillinam; oral
1.3
10.5
1894
16824
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
10.5
258
1673
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.3
10.5
39
120
A07AA02
ATC
nystatin; oral
1.9
10.5
124
655
J01FA10
ATC
azithromycin; systemic
1.3
10.5
2307
20981
N05BA01
ATC
diazepam; systemic, rectal
1.5
10.4
309
2090
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.9
10.4
133
720
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
110.3
10.4
11
*
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
110.3
10.4
11
*
E30.1
ICD-10 Finland
Precocious puberty
+∞
10.4
10
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
10.4
10
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
10.4
89
418
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
0.7
10.4
699
8771
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
10.3
755
5985
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
2.0
10.3
106
533
L04AA01
ATC
[U] ciclosporin
3.5
10.3
34
97
M03BX02
ATC
tizanidine; oral
1.3
10.3
2088
18786
WX720
NOMESCO Finland
Own respiration
1.9
10.3
128
688
L28
ICPC
Limited function/disability (L)
1.5
10.3
338
2338
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
10.2
2876
26919
D06
ICPC
Abdominal pain localized other
1.4
10.2
409
2939
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
10.1
1734
15290
SPAT1139
SPAT
Nutrition survey
2.1
10.1
97
476
L12
ICPC
Hand/finger symptom/complaint
1.4
10.0
633
4907
K02.1
ICD-10 Finland
Caries of dentine
1.3
10.0
2384
21812
M01AH02
ATC
rofecoxib; oral
1.7
10.0
192
1171
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
1.8
10.0
148
840
62400
ICD-8 Finland
Malposition of uterus, Retroversion and retroflexion
14.6
10.0
16
11
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
3.0
10.0
43
145
Z3231
NOMESCO Finland
Registered nurse
1.3
10.0
710
5604
AA1AD
NOMESCO Finland
CT of head and brain
1.4
10.0
497
3711
J01AA02
ATC
doxycycline; systemic
1.3
9.9
2348
21455
R73.0
ICD-10 Finland
Abnormal glucose tolerance test
2.5
9.9
58
230
WX702
NOMESCO Finland
Supraglottic ventilation device
1.7
9.9
163
954
N84.0
ICD-10 Finland
Polyp of corpus uteri
1.6
9.9
218
1378
Z3226
NOMESCO Finland
Physiotherapist
1.4
9.9
442
3238
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
9.9
253
1657
G03DC03
ATC
lynestrenol; oral
1.9
9.9
123
661
A03
ICPC
Fever
1.3
9.8
839
6792
J01MA12
ATC
levofloxacin; systemic
1.5
9.8
353
2485
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.4
9.8
405
2926
E66.1
ICD-10 Finland
Drug-induced obesity
4.9
9.8
21
43
SPAT1229
SPAT
Assessment of need for aid
1.9
9.8
119
635
XLD10
NOMESCO Finland
Gynaecological examination
2.4
9.8
64
268
SPAT1312
SPAT
General health counselling
1.3
9.8
1265
10787
6171A
ICD-9 Finland
Endometriosis of ovary
3.7
9.7
30
82
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
9.6
579
4453
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.4
9.6
64
270
Z30.4
ICD-10 Finland
Surveillance of contraceptive drugs
0.7
9.6
391
5317
SPAT1254
SPAT
Administration of medicine
1.4
9.6
437
3212
K04.0
ICD-10 Finland
Pulpitis
1.4
9.6
391
2818
S10
ICPC
Boil/carbuncle
1.7
9.6
187
1147
N06AX26
ATC
vortioxetine; oral
1.5
9.6
362
2573
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.3
9.6
788
6345
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
9.5
321
2230
LAF00
NOMESCO Finland
Unilateral salpingo-oophorectomy
2.8
9.5
47
171
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
2.1
9.5
87
419
LAF10
NOMESCO Finland
Bilateral salpingo-oophorectomy
2.5
9.5
58
235
WW409
NOMESCO Finland
Other aferesis
15.0
9.5
15
10
N02BF01
ATC
gabapentin; oral
1.5
9.5
284
1926
A10BJ05
ATC
dulaglutide; parenteral
2.9
9.5
44
155
SPAT1097
SPAT
Recording of ECG
1.6
9.5
247
1626
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.5
9.4
276
1863
XKD00
NOMESCO Finland
Uroflowmetry
2.0
9.4
106
551
N05CF01
ATC
zopiclone; oral
1.3
9.4
732
5845
E30.09
ICD-10 Finland
Delayed puberty NOS
100.3
9.4
10
*
N95.0
ICD-10 Finland
Postmenopausal bleeding
1.7
9.4
169
1014
EB1VA, ,
NOMESCO Finland
1.3
9.4
612
4764
B01AC04
ATC
clopidogrel; oral
1.9
9.4
116
623
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
9.3
547
4191
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.4
9.3
370
2655
D11
ICPC
Diarrhoea
1.4
9.2
554
4260
N03AX11
ATC
topiramate; oral
1.8
9.2
123
677
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
9.2
255
1703
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
9.1
689
5477
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
9.1
166
1001
R50.9
ICD-10 Finland
Fever, unspecified
1.4
9.1
467
3503
A02BA02
ATC
ranitidine; systemic
1.5
9.1
338
2395
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.4
9.1
61
259
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
9.0
1924
17289
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
3.4
9.0
31
91
127
Kela drug reimbursment
Transplant complication
3.3
9.0
33
101
XF404
NOMESCO Finland
Ambulatory ECG
1.7
9.0
146
852
QBJ30
NOMESCO Finland
Correction of abdominal apron
2.6
9.0
51
200
N02BF02
ATC
pregabalin; oral
1.6
9.0
203
1293
-1, ,
ICPC
1.9
9.0
104
547
K10.3
ICD-10 Finland
Alveolitis of jaws
1.6
8.9
224
1461
Z71.8
ICD-10 Finland
Other specified counselling
1.2
8.9
1399
12159
G02CB01
ATC
bromocriptine; systemic
2.2
8.9
73
338
6173A
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS SEROSAE PELVIS]
3.9
8.9
25
64
P03
ICPC
Feeling depressed
1.3
8.8
610
4787
WX290
NOMESCO Finland
Other blockage of nerve
1.2
8.8
2097
19044
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
8.8
199
1267
F32.1
ICD-10 Finland
Moderate depressive episode
1.4
8.8
346
2477
F43.1
ICD-10 Finland
Post-traumatic stress disorder
1.6
8.7
191
1206
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.3
8.7
539
4159
P01
ICPC
Feeling anxious/nervous/tense
1.3
8.7
903
7478
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
50.1
8.7
10
*
E23.2
ICD-10 Finland
Diabetes insipidus
50.1
8.7
10
*
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
2.0
8.6
91
463
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
8.6
170
1046
J01DA01
ATC
[U] cefalexin
1.2
8.6
1989
17986
6202X
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Other and unspecified ovarian cyst
3.3
8.6
32
99
R60.0
ICD-10 Finland
Localized oedema
1.5
8.6
255
1726
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
8.6
203
1306
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.6
8.6
204
1314
B01AB10
ATC
tinzaparin; parenteral
1.5
8.6
262
1784
SPAT1307
SPAT
Psychosocial counselling and guidance
1.4
8.6
409
3029
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.8
8.6
134
774
UDC00
NOMESCO Finland
Ear microscopy
1.6
8.5
202
1300
OAB42, ,
SPAT
1.4
8.5
499
3818
J01EA01
ATC
trimethoprim; systemic
1.3
8.5
934
7782
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
1.7
8.5
147
873
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.5
8.5
297
2078
SFA30
NOMESCO Finland
Three-surface restoration
1.2
8.5
1210
10392
N85.1
ICD-10 Finland
Endometrial adenomatous hyperplasia
3.4
8.5
30
90
SFA10
NOMESCO Finland
One-surface restoration
1.2
8.4
2126
19380
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.7
8.4
148
883
N83.0
ICD-10 Finland
Follicular cyst of ovary
2.1
8.4
76
365
RD210, ,
NOMESCO Finland
2.3
8.4
61
268
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.8
8.4
118
660
G03FB01
ATC
norgestrel and estrogen; systemic
3.6
8.4
27
76
N05CF02
ATC
zolpidem; oral
1.3
8.4
503
3865
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
1.5
8.4
285
1985
104
Kela drug reimbursment
Thyroid insufficiency
1.7
8.4
158
962
H02AB04
ATC
methylprednisolone; systemic
1.4
8.3
344
2484
E03
ICD-10 Finland
Other hypothyroidism
1.6
8.3
210
1372
2561A
ICD-9 Finland
Ovarian dysfunction, Other ovarian hyperfunction
+∞
8.3
8
*
E30.9
ICD-10 Finland
Disorder of puberty, unspecified
+∞
8.3
8
*
D39.10
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary without histology
2.0
8.3
84
421
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
8.3
1103
9393
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
8.3
209
1365
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
1.9
8.3
93
484
G04CA02
ATC
tamsulosin; oral
2.2
8.3
64
289
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
8.3
498
3827
A46
ICD-10 Finland
Erysipelas
1.6
8.2
207
1352
LAC01
NOMESCO Finland
Laparoscopic excision of ovarian cyst
2.0
8.2
84
423
LCH11
NOMESCO Finland
Pharmacologic abortion
0.6
8.2
143
2320
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.5
8.2
50
203
N99.4
ICD-10 Finland
Postprocedural pelvic peritoneal adhesions
3.3
8.2
30
92
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.4
8.2
390
2888
J20
ICD-10 Finland
Acute bronchitis
1.4
8.2
344
2493
C08CA13
ATC
lercanidipine; oral
1.6
8.1
166
1031
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.4
8.1
352
2566
WX402
NOMESCO Finland
General anaesthesia
1.3
8.1
690
5569
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
8.1
220
1463
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.4
8.0
433
3271
L01
ICPC
Neck symptom/complaint
1.3
8.0
645
5164
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
1.9
8.0
89
462
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.5
8.0
286
2011
R09
ICPC
Sinus symptom/complaint
1.4
8.0
417
3136
KH1AD
NOMESCO Finland
CT of urinary organs
2.0
7.9
80
401
N97
ICD-10 Finland
Female infertility
2.1
7.9
70
334
SPAT1216
SPAT
Assessment of functional ability
1.5
7.9
256
1765
JDF01
NOMESCO Finland
Laparoscopic gastroplasty
3.0
7.9
33
110
S29
ICPC
Skin symptom/complaint other
1.3
7.9
618
4932
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.4
7.9
301
2144
M04AA01
ATC
allopurinol; systemic
1.9
7.9
89
465
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.6
7.8
201
1319
TLC00, ,
SPAT
0.6
7.8
98
1735
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
6.1
7.8
20
33
B37.08
ICD-10 Finland
Other candidal stomatitis
3.5
7.8
26
75
F34.1
ICD-10 Finland
Dysthymia
1.7
7.8
150
918
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
7.8
1486
13129
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
1.7
7.8
149
911
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.8
7.7
111
626
L73.2
ICD-10 Finland
Hidradenitis suppurativa
2.1
7.7
66
311
L16
ICPC
Ankle symptom/complaint
1.4
7.7
438
3335
WW300
NOMESCO Finland
Transfer of autologic stem cells
15.0
7.7
12
8
N80.1
ICD-10 Finland
Endometriosis of ovary
1.6
7.7
160
999
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
1.9
7.6
97
527
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
7.6
802
6640
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
1.8
7.6
119
689
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.3
7.6
54
236
Q96.9
ICD-10 Finland
Turner syndrome, unspecified
25.1
7.6
10
*
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
1.8
7.5
105
587
Z31.5
ICD-10 Finland
Genetic counselling
1.5
7.5
254
1766
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.5
7.5
227
1543
H66.9
ICD-10 Finland
Otitis media, unspecified
1.4
7.5
334
2443
G02BA03
ATC
plastic IUD with progestogen
0.7
7.5
402
5245
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.5
7.5
46
188
N96
ICD-10 Finland
Habitual aborter
2.3
7.5
52
225
K08.80
ICD-10 Finland
Toothache NOS
1.4
7.4
378
2829
Q96.8
ICD-10 Finland
Other variants of Turner syndrome
80.3
7.4
8
*
E26.0
ICD-10 Finland
Primary hyperaldosteronism
80.3
7.4
8
*
SPAT1050
SPAT
Extensive neurological examination
2.1
7.4
63
297
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
1.7
7.4
130
778
62600
ICD-8 Finland
Disorders of menstruation, Absent
13.4
7.4
12
9
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.5
7.3
255
1784
W84
ICPC
Pregnancy high risk
1.4
7.3
311
2257
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
1.6
7.3
153
957
J01FA09
ATC
clarithromycin; systemic
1.2
7.3
993
8455
A11CC03
ATC
alfacalcidol; systemic
2.9
7.3
33
115
TLW14
NOMESCO Finland
ICSI
2.2
7.3
59
272
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
7.3
234
1611
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.5
7.3
203
1357
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.6
7.3
159
1005
25899
ICD-8 Finland
Polyglandular dysfunction and other diseases of endocrine glands, Other and unspecified diseases of endocrine system
+∞
7.3
7
*
25600
ICD-8 Finland
Ovarian dysfunction, Hyperfunction
+∞
7.3
7
*
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
+∞
7.3
7
*
N30.9
ICD-10 Finland
Cystitis, unspecified
1.5
7.3
241
1670
C10AB05
ATC
fenofibrate; oral
3.2
7.3
28
89
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
2.1
7.2
64
306
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.3
7.2
691
5650
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
7.2
126
752
A11CC02
ATC
dihydrotachysterol; oral
15.8
7.2
11
7
R33
ICD-10 Finland
Retention of urine
2.0
7.2
74
374
L08
ICPC
Shoulder symptom/complaint
1.3
7.2
594
4767
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.3
7.2
826
6901
62650
ICD-8 Finland
Disorders of menstruation, Irregular
5.8
7.2
19
33
B82
ICPC
Anaemia other/unspecified
2.0
7.2
70
347
N06AA09
ATC
amitriptyline; systemic
1.6
7.2
169
1088
A10BH05
ATC
linagliptin; oral
2.4
7.2
45
186
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
1.8
7.2
103
582
HAMTE, ,
NOMESCO Finland
2.8
7.2
34
122
K04.1
ICD-10 Finland
Necrosis of pulp
1.4
7.1
356
2655
R4110, ,
SPAT
1.4
7.1
313
2285
B01AB04
ATC
dalteparin; parenteral
1.7
7.1
123
732
C07AA05
ATC
propranolol; systemic
1.3
7.1
760
6299
XG410
NOMESCO Finland
Flow-volume spirometry
1.9
7.1
78
405
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.7
7.1
37
140
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
1.4
7.0
374
2818
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.4
7.0
45
188
6200A
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Follicular cyst of ovary
4.2
7.0
18
43
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
1.5
7.0
206
1394
Z3229
NOMESCO Finland
Other healthcare associate professional
1.6
7.0
161
1032
UJD02
NOMESCO Finland
Gastroscopy
1.8
7.0
91
499
P99
ICPC
Psychological disorders other
1.6
6.9
148
932
R03BA01
ATC
beclometasone; inhalant
1.4
6.9
364
2739
Z2446
NOMESCO Finland
Social worker
1.5
6.9
192
1284
P29
ICPC
Psychological sympt/compl other
1.3
6.9
433
3349
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
6.8
557
4461
R13
ICD-10 Finland
Dysphagia
1.6
6.8
146
919
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.3
6.8
644
5255
ZXF99
NOMESCO Finland
Other r3eason to interrupt procedure
6.7
6.8
16
24
61520
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Cysta (cystis) follicularis ovarii (retentio)
3.8
6.8
20
53
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
1.8
6.8
93
518
N03AG01
ATC
valproic acid; systemic, rectal
1.6
6.8
169
1103
JAL96
NOMESCO Finland
Other excision of lesion of peritoneum
10.9
6.8
12
11
Z02.7
ICD-10 Finland
Issue of medical certificate
1.5
6.8
215
1478
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
9.3
6.8
13
14
SPAT1255
SPAT
Intravenous administration of medicine
1.6
6.8
137
851
SGC00
NOMESCO Finland
Medication, disinfection of root canals
1.4
6.8
380
2888
S06.0
ICD-10 Finland
Concussion
1.4
6.8
336
2505
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
40.1
6.8
8
*
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
16.7
6.7
10
6
K30
ICD-10 Finland
Functional dyspepsia
1.4
6.7
378
2873
G03FA14
ATC
dydrogesterone and estrogen; systemic
1.6
6.7
147
931
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.5
6.7
238
1672
C10AX09
ATC
ezetimibe; oral
1.5
6.7
182
1211
A10BX07
ATC
[U] liraglutide
3.5
6.7
22
63
XF600, ,
SPAT
2.0
6.7
68
343
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.5
6.7
184
1228
R44
ICPC
Respiratory, Preventive immunization/medic
3.2
6.7
25
78
R12
ICD-10 Finland
Heartburn
1.4
6.7
280
2029
62611
ICD-8 Finland
Disorders of menstruation, Oligomenorrhoea
22.5
6.7
9
*
N20.1
ICD-10 Finland
Calculus of ureter
2.1
6.6
60
290
160
Kela drug reimbursment
exenatide
2.9
6.6
30
105
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
1.8
6.6
91
508
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.0
6.6
27
89
R01AD09
ATC
mometasone; nasal
1.2
6.6
1732
15690
M01AG02
ATC
tolfenamic acid; oral, rectal
1.3
6.6
538
4312
A10AE05
ATC
insulin detemir; parenteral
1.7
6.6
116
696
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.1
6.6
58
278
M01AC06
ATC
meloxicam; systemic, rectal
1.2
6.5
812
6838
A01AB04
ATC
amphotericin B; local oral
2.0
6.5
67
340
Z30.5
ICD-10 Finland
Surveillance of (intrauterine) contraceptive device
0.7
6.5
283
3816
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.2
6.5
50
227
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
1.7
6.4
112
669
C03AA03
ATC
hydrochlorothiazide; oral
1.8
6.4
87
483
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.4
6.4
301
2222
A03CA02
ATC
clidinium and psycholeptics; oral
1.9
6.4
74
390
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
70.0
6.4
7
*
E27.9
ICD-10 Finland
Disorder of adrenal gland, unspecified
70.0
6.4
7
*
G93.2
ICD-10 Finland
Benign intracranial hypertension
3.3
6.4
23
70
SPAT1360
SPAT
Extensive global examination
1.5
6.4
163
1070
W11
ICPC
Contraception oral
0.8
6.4
649
7807
UJF92
NOMESCO Finland
Capsular endoscopy
1.9
6.4
72
377
3055, ,
Kela drug reimbursment
2.4
6.4
43
184
G03DC05
ATC
[U] tibolone
2.3
6.4
46
203
M01AB05
ATC
diclofenac; systemic, rectal
1.2
6.4
1956
17947
XG466
NOMESCO Finland
Sleep oxymetry
2.3
6.3
45
197
J35.0
ICD-10 Finland
Chronic tonsillitis
1.4
6.3
313
2332
UJF30
NOMESCO Finland
Ileoscopy through colon
1.4
6.3
257
1852
JAH00
NOMESCO Finland
Laparotomy
2.3
6.3
47
210
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
8.1
6.3
13
16
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
1.7
6.3
98
568
SPAT1234
SPAT
Support of social functional capacity
1.8
6.3
93
531
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.4
6.3
41
173
A03FA02
ATC
cisapride; oral, rectal
1.6
6.3
133
837
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
6.3
39
161
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.7
6.3
111
667
D64.9
ICD-10 Finland
Anaemia, unspecified
1.6
6.3
142
908
T89
ICPC
Diabetes insulin dependent
1.7
6.3
117
713
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
1.4
6.3
279
2044
Q96
ICD-10 Finland
Turner syndrome
+∞
6.2
6
*
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
6.2
6
*
2568X
ICD-9 Finland
Ovarian dysfunction, Other ovarian dysfunction
+∞
6.2
6
*
318
Kela drug reimbursment
Teriparatide
+∞
6.2
6
*
E30.8
ICD-10 Finland
Other disorders of puberty
+∞
6.2
6
*
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
1.9
6.2
72
380
R51.81
ICD-10 Finland
Facial pain NOS
1.8
6.2
84
466
B01AA03
ATC
warfarin; systemic
1.6
6.2
136
862
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.5
6.2
159
1045
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
6.2
515
4133
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
6.2
80
438
F51.0
ICD-10 Finland
Nonorganic insomnia
1.2
6.2
784
6609
N71.1
ICD-10 Finland
Chronic inflammatory disease of uterus
3.7
6.2
19
52
M01AX17
ATC
nimesulide; oral
1.3
6.2
361
2760
K92.1
ICD-10 Finland
Melaena
1.9
6.2
75
403
N80.0
ICD-10 Finland
Endometriosis of uterus
1.7
6.2
103
609
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
1.8
6.2
84
468
WVA20
NOMESCO Finland
Medicine administration
1.9
6.2
69
361
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
6.2
1523
13696
WX780
NOMESCO Finland
Remote monitoring CPAP
1.8
6.1
88
498
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.5
6.1
181
1227
F45.8
ICD-10 Finland
Other somatoform disorders
1.3
6.1
370
2843
D70.82
ICD-10 Finland
Drug-induced neutropenia
2.6
6.1
33
127
O20.0
ICD-10 Finland
Threatened abortion
1.6
6.1
133
842
R03AK08
ATC
formoterol and beclometasone; inhalant
1.6
6.1
127
795
Z2221
NOMESCO Finland
Medical doctor
1.2
6.1
877
7491
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
6.1
936
8049
XKC03
NOMESCO Finland
Water cystometry
2.1
6.1
56
273
EMB10
NOMESCO Finland
Tonsillectomy
1.4
6.1
333
2523
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.6
6.0
130
821
R74
ICPC
Upper respiratory infection acute
1.2
6.0
1706
15509
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
6.0
269
1970
Z34
ICD-10 Finland
Supervision of normal pregnancy
0.7
6.0
191
2722
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.3
6.0
43
189
T29
ICPC
Endocr/metab/nutr sympt/compl other
2.4
6.0
38
158
N02AC04
ATC
dextropropoxyphene; oral
2.5
6.0
36
146
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
1.9
6.0
76
414
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
735
770
11.68
307.65
1.5
1.3
1.59
1.60
nmol/l
0.04
674
661
476
409
13.22
307.65
1.3
1.1
6.88
6.30
umol/l
1.76
454
367
1006
1714
7.70
307.65
1.5
1.2
13.01
9.10
u/l
8.79
837
1401
259
121
22.95
307.65
1.3
1.1
7.62
5.21
nmol/l
9.91
250
113
1011
3133
4.07
285.37
1.8
1.3
280.11
296.39
mu/l
0.91
949
2761
730
1937
4.45
251.81
1.3
1.3
7.54
3.13
ug/l
15.22
634
1855
199
148
14.16
214.48
1.4
1.2
23.58
17.55
pmol/l
2.27
185
132
1057
4135
3.18
199.90
1.6
1.3
16.78
20.11
iu/l
3.14
899
3548
539
1349
4.51
198.04
1.8
1.4
0.43
0.53
nmol/l
0.92
463
1128
221
328
7.10
142.70
2.3
3.6
29.34
29.66
mu/l
0.04
216
308
409
1077
4.15
138.71
1.6
1.3
14.34
19.43
u/l
3.45
374
894
373
977
4.14
127.09
1.8
1.4
356.91
373.09
mu/l
0.31
350
780
71
25
28.94
106.13
1.0
1.0
—
—
—
0
0
673
3126
2.41
83.07
2.4
1.8
358.98
395.72
nmol/l
5.05
634
2893
278
819
3.59
79.18
1.5
1.5
34.16
36.67
nmol/l
0.34
259
751
3296
28447
2.52
65.67
6.3
4.7
14.33
14.20
pmol/l
2.89
3167
26877
2187
16596
1.78
61.18
4.6
3.9
6.29
6.09
mmol/l
5.17
1974
14694
3144
26847
2.17
60.08
5.7
4.1
37.30
36.19
mmol/mol
11.91
3027
25737
3493
31523
3.12
54.36
7.5
5.6
1.66
1.70
mu/l
0.95
3410
30357
911
5485
1.88
54.11
4.3
4.2
9.06
11.30
mg/mmol
0.69
593
3499
1542
10906
1.71
52.48
4.7
4.0
36.77
37.32
g/l
3.85
1469
10278
3265
28657
2.23
52.39
4.7
3.5
5.64
5.48
mmol/l
13.35
3134
27167
1616
11705
1.68
49.37
6.4
4.8
1.22
1.21
mmol/l
0.60
1410
10165
1850
13932
1.66
48.20
5.5
4.9
9.08
9.37
umol/l
0.96
1747
13132
2616
21621
1.73
47.13
7.7
6.5
72.98
70.45
u/l
3.63
2507
20539
484
2441
2.13
47.10
4.6
4.4
1.07
1.05
mmol/l
0.94
461
2243
1291
8912
1.69
46.61
2.6
2.4
59.33
55.69
u/l
0.30
1215
8295
1134
7643
1.70
44.29
3.4
3.3
8.09
7.88
mmol/l
0.64
988
6808
1420
10215
1.64
42.71
5.8
4.4
1.22
1.21
mmol/l
0.54
1334
9494
3364
30393
2.24
41.88
13.9
9.4
3.89
3.88
mmol/l
2.58
3298
29574
3359
30365
2.21
41.17
13.8
9.4
139.45
139.45
mmol/l
0.02
3301
29636
1905
14809
1.59
40.92
2.9
2.3
70.52
72.69
nmol/l
3.34
1812
14024
710
4313
1.80
39.41
1.3
1.3
124.90
147.45
u/ml
0.70
261
1707
1526
11338
1.59
39.17
2.2
1.8
95.84
98.79
pmol/l
1.90
872
6344
97
222
4.46
39.05
1.4
1.2
369.00
387.28
mu/l
0.14
97
209
1302
9332
1.61
38.77
6.9
6.1
1.06
1.06
inr
0.44
1086
7711
98
231
4.33
38.00
1.4
1.2
70.76
73.06
%
0.68
98
218
114
306
3.81
37.07
2.1
1.3
51.96
21.80
ng/l
1.89
114
306
1021
6979
1.64
36.40
1.8
1.5
19.77
20.44
nmol/l
0.90
919
6260
1522
11503
1.55
35.05
1.9
1.7
1.47
1.26
mmol/l
15.45
1345
10268
1443
10792
1.55
34.75
3.3
2.9
28.42
26.89
u/l
0.83
1368
10306
165
603
2.82
32.44
1.2
1.2
9.44
2918.06
iu/ml
0.96
32
164
77
171
4.58
32.21
1.9
1.4
1.10
2.56
nmol/l
0.99
64
121
580
3533
1.76
31.23
3.4
2.9
0.82
0.83
mmol/l
0.58
554
3342
916
6298
1.60
31.06
2.3
2.1
310.36
291.72
umol/l
8.44
844
5750
1169
8603
1.53
28.97
2.5
2.1
2.51
2.51
mg/l
0.02
1049
7483
1203
8916
1.52
28.80
3.0
2.8
2.34
2.34
mmol/l
0.73
1117
8293
3301
30343
1.85
28.19
4.8
3.8
2.83
2.81
mmol/l
0.72
3176
29125
827
5661
1.59
28.16
2.9
2.3
6210.73
7085.52
u/l
0.39
366
2324
2056
17111
1.46
26.65
6.4
6.1
0.18
0.18
e9/l
0.42
1883
15389
2658
23282
1.51
26.39
4.6
3.9
10.11
8.79
mm/h
9.21
2545
22074
1992
16499
1.45
26.35
6.2
6.0
0.04
0.04
e9/l
1.28
1786
14615
1989
16481
1.45
26.17
6.2
6.0
0.53
0.52
e9/l
2.55
1786
14612
621
4036
1.65
25.91
2.2
2.1
2.60
2.52
g/l
3.08
569
3729
337
1837
1.92
25.76
1.5
1.4
—
—
—
0
0
2662
23370
1.50
25.72
5.1
4.1
1873.40
2249.21
e6/l
0.09
42
257
470
2845
1.75
25.53
3.5
3.5
4.59
4.59
pmol/l
0.05
425
2593
1411
11006
1.46
25.34
1.5
1.4
1.39
1.52
u/ml
0.14
416
3320
3265
30084
1.75
25.33
4.5
3.5
1.43
1.54
mmol/l
40.47
3152
28908
3089
28070
1.62
25.08
3.8
3.1
1.35
1.13
mmol/l
39.41
2974
26910
3272
30200
1.75
24.78
4.6
3.6
4.70
4.73
mmol/l
1.13
3166
29116
2226
18947
1.44
24.64
3.9
3.5
0.02
0.01
estimate
0.22
453
4066
1085
8087
1.48
24.39
2.6
2.4
16.44
36.77
ng/l
0.84
427
2963
2036
17066
1.43
24.39
6.2
5.9
2.10
2.00
e9/l
5.20
1868
15495
2549
22293
1.47
24.15
3.9
3.4
58.85
56.89
ug/l
0.53
2452
21342
2197
18691
1.44
24.12
3.8
3.4
0.00
0.00
estimate
0.00
463
4141
669
4509
1.59
23.87
2.3
2.1
13.78
14.94
umol/l
4.02
624
4217
2210
18868
1.43
23.48
3.9
3.4
2.89
3.79
estimate
0.11
464
4141
2148
18293
1.42
22.82
8.7
8.2
4.14
3.99
e9/l
2.78
1923
16108
587
3906
1.60
21.95
2.4
2.6
503.32
502.27
ng/l
0.00
465
3086
1868
15597
1.40
21.80
6.1
5.7
56.25
56.33
%
0.11
1798
14981
515
3330
1.64
21.64
1.9
1.6
1210.47
1169.14
nmol/l
0.52
428
2582
260
1376
1.96
21.63
3.2
2.7
85.50
65.04
ng/l
0.87
231
1242
541
3550
1.61
21.39
2.3
2.2
21.89
24.07
%
3.57
490
3301
224
1129
2.05
21.38
3.7
2.6
5.08
5.08
kpa
0.07
210
1088
1889
15833
1.40
21.38
6.2
5.8
30.25
30.06
%
0.38
1807
15090
55
130
4.28
21.35
1.8
1.5
128.56
127.43
nmol/l
0.07
55
130
1008
7576
1.46
21.13
2.0
1.8
0.81
0.92
mg/l
1.03
747
5594
3501
33244
2.09
20.88
15.8
11.1
65.22
64.84
umol/l
0.48
3467
32871
3174
29347
1.59
20.41
11.6
8.6
97.67
96.97
ml/min/173m2
1.20
2853
26144
542
3605
1.59
20.18
1.9
1.7
—
—
—
0
0
745
5320
1.50
20.08
1.8
1.6
15988335.29
34606778.42
pmol/l
0.73
663
4687
485
3179
1.61
19.14
2.6
2.3
5.12
5.39
umol/l
0.29
406
2659
1990
17029
1.37
18.74
2.9
2.6
—
—
estimate
—
0
0
331
1989
1.73
18.23
2.2
2.2
0.23
0.23
g/l
1.14
310
1882
54
142
3.84
18.20
1.8
1.2
87.69
72.48
nmol/24h
0.89
54
142
191
966
2.03
18.07
3.5
2.5
1.15
1.19
mmol/l
0.06
133
665
3440
32694
1.80
17.19
14.6
10.6
18.07
18.78
mg/l
0.74
2984
26081
3499
33452
1.93
16.82
11.5
8.9
26.65
22.90
u/l
22.66
3446
32714
553
3855
1.51
16.44
3.1
2.8
169.45
267.45
ng/l
0.58
272
1731
378
2429
1.62
16.07
1.7
1.6
—
—
—
0
0
963
7495
1.39
15.74
1.4
1.4
25.26
20.60
iu/ml
0.63
273
2102
357
2280
1.63
15.55
4.0
3.9
223.64
226.94
u/l
0.18
339
2172
1144
9195
1.35
15.16
1.6
1.4
1.99
2.04
g/l
0.71
726
6135
372
2423
1.60
14.93
2.6
2.4
25.38
41.30
u/ml
1.98
360
2353
126
588
2.18
14.76
3.9
2.7
24.57
24.47
mmol/l
0.19
117
555
881
6869
1.37
13.97
1.4
1.3
9.50
8.28
u/ml
0.26
344
2959
867
6743
1.37
13.97
2.2
2.0
189.95
125.45
u/l
0.43
841
6445
76
291
2.65
13.82
1.3
1.4
—
—
titre
—
0
0
1043
8362
1.35
13.78
3.6
3.3
1.02
1.58
kg/l
1.08
681
5382
1678
14390
1.31
13.73
3.7
3.2
0.06
0.21
estimate
0.52
392
3468
334
2167
1.60
13.60
1.2
1.1
0.76
2.26
u/ml
—
5
19
357
2354
1.57
13.57
1.8
1.6
—
—
—
0
0
43
123
3.53
12.92
2.8
2.2
1.98
1.39
nmol/l
1.72
36
99
411
2831
1.51
12.78
4.0
3.2
31.02
33.37
%
4.27
334
2147
268
1673
1.65
12.76
1.8
1.6
—
—
—
0
0
1085
8829
1.32
12.76
3.2
2.7
24.28
76.69
e6/l
2.46
806
6397
243
1481
1.69
12.68
6.5
7.6
124.43
120.38
g/l
2.85
237
1448
768
5939
1.37
12.66
2.7
2.3
10.73
9.56
e6/l
0.89
693
5300
1374
11627
1.29
11.88
3.8
3.3
60.00
67.69
e6/l
0.22
889
7216
248
1547
1.65
11.85
6.4
7.3
96.16
96.68
%
0.64
239
1493
592
4436
1.40
11.73
2.3
2.2
2.41
2.40
mmol/l
0.85
518
3942
171
971
1.80
11.48
2.6
2.5
72.14
92.20
ng/l
0.90
155
862
107
522
2.08
11.27
1.5
1.2
—
—
—
0
0
89
407
2.22
11.05
3.0
4.4
261.37
99.82
u/ml
0.49
27
137
278
1814
1.58
11.04
6.4
6.9
13.13
14.08
kpa
2.28
266
1744
219
1348
1.66
11.03
1.1
1.1
1.97
5.07
eliau/ml
2.19
29
224
92
427
2.18
11.01
2.3
1.9
6.62
5.93
pmol/l
0.52
92
427
277
1813
1.57
10.86
6.4
6.9
4.92
4.99
kpa
0.75
267
1746
1197
10053
1.28
10.70
4.0
3.4
0.01
0.00
estimate
0.29
458
3995
164
944
1.77
10.54
6.4
5.9
23.94
24.02
mmol/l
0.10
156
898
128
682
1.91
10.53
5.1
3.9
1.65
1.72
%
0.28
121
640
462
3379
1.42
10.46
2.4
2.0
28.60
28.89
s
0.69
454
3261
350
2433
1.48
10.37
3.1
2.6
10.19
10.49
g/l
0.95
324
2276
936
7644
1.30
10.32
3.1
2.6
0.24
0.27
e6/l
0.18
665
5302
271
1791
1.55
10.18
6.3
6.9
0.48
0.52
mmol/l
0.05
221
1385
94
456
2.09
10.08
2.0
3.0
1.06
0.88
nmol/l
1.11
74
396
222
1404
1.62
10.06
2.9
2.5
77.91
70.62
e9/l
1.89
167
980
2597
24019
1.28
9.93
3.5
2.8
33.89
28.87
u/l
6.14
2507
23170
255
1675
1.56
9.85
3.1
3.3
1.63
1.49
mmol/l
0.31
219
1446
153
882
1.77
9.80
7.4
8.2
16.72
16.05
%
2.61
145
842
999
8279
1.28
9.74
2.2
1.9
—
—
—
0
0
55
216
2.57
9.61
2.7
1.5
285.25
283.40
mosm/kgh2o
0.22
44
174
775
6236
1.31
9.43
2.4
2.6
108.12
93.69
ug/g
0.65
596
4863
151
879
1.75
9.37
1.4
1.3
—
—
—
0
0
58
240
2.44
9.11
1.2
1.1
10.86
19.30
u/ml
—
7
30
281
1927
1.50
8.90
1.5
1.4
—
—
—
0
0
245
1637
1.53
8.78
1.4
1.3
1.69
1.18
u/ml
0.14
14
113
271
1853
1.50
8.71
2.1
1.9
1.32
1.38
g/l
0.22
256
1741
21
32
6.59
8.64
1.2
1.0
13.70
12.10
pmol/l
0.27
21
32
191
1210
1.61
8.63
1.7
2.1
43.41
39.29
u/l
1.96
181
1149
102
540
1.91
8.62
4.1
4.7
158.22
587.87
iu/ml
—
9
47
111
605
1.86
8.59
2.5
2.2
24.31
24.30
mmol/l
0.01
106
596
341
2452
1.43
8.46
4.6
4.0
—
—
—
0
0
825
6795
1.28
8.25
4.0
3.2
98.04
97.69
%
0.18
801
6609
65
299
2.20
8.06
1.5
1.3
517.25
413.23
pmol/l
0.64
56
264
249
1713
1.49
7.79
3.7
2.4
1.22
1.23
mmol/l
0.62
219
1439
179
1154
1.58
7.55
2.4
2.3
3.79
3.61
g/l
0.89
174
1079
1282
11191
1.22
7.49
3.2
2.7
0.02
0.12
estimate
0.72
392
3462
67
322
2.10
7.46
7.0
5.6
106.02
106.02
mmol/l
0.00
62
290
367
2733
1.38
7.43
2.6
2.3
39.09
34.13
u/l
0.37
303
2288
77
392
1.98
7.35
3.1
2.5
—
—
—
0
0
209
1404
1.52
7.34
6.4
5.9
6.88
6.28
mmol/l
0.96
202
1358
67
325
2.08
7.30
1.1
1.1
1.05
1.05
ratio
0.11
60
268
187
1230
1.55
7.24
1.4
1.3
36.86
36.08
u/ml
0.01
17
84
110
632
1.76
7.22
5.5
4.0
0.89
0.92
%
0.22
104
593
48
204
2.37
7.19
1.0
1.0
91.98
86.51
%
0.74
42
163
174
1137
1.56
6.95
1.4
1.4
1.97
13.50
u/ml
4.24
21
179
25
78
3.22
6.69
1.8
1.2
0.19
0.43
nmol/l
1.80
20
57
226
1576
1.46
6.63
2.0
1.8
0.01
0.04
estimate
0.91
81
635
197
1337
1.50
6.62
2.2
2.3
3.93
3.74
iu/l
0.10
88
626
172
1141
1.53
6.44
1.4
1.4
3.17
5.20
u/ml
0.47
15
109
1614
14565
1.19
6.32
10.2
8.8
0.00
0.00
e9/l
0.77
1328
12004
235
1670
1.43
6.26
5.2
6.1
1.29
1.21
mmol/l
0.80
230
1635
46
207
2.24
6.10
2.2
1.5
—
—
—
0
0
104
625
1.68
5.89
1.1
1.1
119.55
115.85
%
0.70
98
562
42
185
2.28
5.87
2.5
2.5
57.94
52.72
%
1.00
36
162
3071
29488
1.25
5.84
16.9
12.8
13.41
13.25
%
12.24
3041
29122
56
278
2.03
5.81
2.5
3.0
1.59
1.57
%
0.01
49
256
1029
8984
1.20
5.66
2.2
2.1
—
—
—
0
0
104
634
1.66
5.60
1.4
1.3
—
—
—
0
0
100
606
1.67
5.51
1.9
1.5
—
—
—
0
0
3641
35981
2.10
5.36
23.0
16.6
89.33
89.84
fl
10.81
3630
35786
67
365
1.85
5.34
1.5
1.4
—
—
—
0
0
242
1780
1.38
5.33
2.2
2.3
4.35
5.16
umol/l
1.33
177
1302
3641
35984
2.09
5.31
23.2
16.8
40.04
40.18
%
0.27
3626
35767
3642
35998
2.11
5.30
23.2
16.8
133.23
132.67
g/l
2.53
3630
35802
50
247
2.04
5.29
2.1
1.5
—
—
—
0
0
3641
35986
2.08
5.27
23.0
16.7
4.51
4.46
e12/l
15.63
3598
35458
3640
35974
2.06
5.25
23.1
16.7
275.37
269.64
e9/l
6.85
3601
35492
118
755
1.58
5.25
1.8
2.3
10.31
10.70
mg/l
0.23
111
731
3641
35991
2.07
5.19
23.1
16.7
7.10
6.83
e9/l
10.02
3596
35436
66
362
1.84
5.16
1.5
1.4
—
—
—
0
0
136
903
1.53
5.14
1.4
1.3
2.97
3.61
u/ml
—
9
63
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
63
342
1.86
5.09
3.8
4.0
0.38
0.37
iu/ml
0.07
41
174
27
104
2.61
5.05
1.4
1.3
—
—
—
0
0
67
372
1.82
5.04
1.5
1.4
—
—
—
0
0
86
516
1.68
4.96
2.2
1.8
0.88
1.91
ug/l
0.91
78
460
63
346
1.84
4.92
1.5
1.4
—
—
—
0
0
179
1268
1.43
4.91
2.3
2.2
67.15
67.74
g/l
0.47
171
1199
62
339
1.84
4.91
1.2
1.2
—
0.44
nmol/l
—
0
5
48
241
2.00
4.88
2.5
2.3
10.67
13.24
%
1.44
48
235
110
705
1.58
4.88
1.5
1.3
316.28
320.75
ug/g
0.06
55
321
27
106
2.56
4.87
1.4
1.3
—
—
—
0
0
50
255
1.97
4.87
3.2
2.6
229.39
208.86
e6/l
0.31
41
210
63
348
1.82
4.84
1.5
1.4
—
—
—
0
0
37
169
2.20
4.80
2.1
1.4
—
—
—
0
0
37
169
2.20
4.80
2.1
1.4
—
—
—
0
0
37
169
2.20
4.80
2.1
1.4
—
—
—
0
0
63
349
1.82
4.80
1.5
1.4
—
—
—
0
0
59
325
1.83
4.59
1.2
1.2
—
—
—
0
0
227
1697
1.36
4.56
2.2
2.2
7.13
7.10
iu/ml
0.00
57
435
37
173
2.15
4.55
2.4
1.6
0.56
0.39
mmol/l
0.10
37
161
59
326
1.82
4.55
1.2
1.2
—
—
—
0
0
72
424
1.71
4.48
1.3
1.2
—
—
—
0
0
72
424
1.71
4.48
1.3
1.2
—
—
—
0
0
52
278
1.88
4.45
1.1
1.1
0.15
0.22
nmol/l
0.43
30
191
59
329
1.81
4.42
2.7
2.7
32.60
106.81
ug/min
1.83
39
227
89
559
1.61
4.34
1.9
1.5
—
—
—
0
0
136
938
1.47
4.33
1.3
1.3
400.52
440.03
mg/l
0.74
130
897
37
177
2.10
4.32
1.1
1.2
—
—
—
0
0
249
1908
1.33
4.26
2.5
2.1
0.40
0.29
e6/l
0.33
235
1778
91
579
1.59
4.22
1.5
1.4
—
—
—
0
0
143
1003
1.44
4.19
2.3
2.0
—
—
—
0
0
120
815
1.49
4.14
1.3
1.4
347.40
5626.31
e6/l
0.59
99
636
376
3053
1.26
4.12
1.4
1.3
120.17
177.09
u/ml
1.92
349
2858
154
1100
1.42
4.09
1.7
1.5
—
—
—
0
0
142
1000
1.44
4.08
7.1
8.9
94.18
94.69
%
0.43
142
995
118
802
1.49
4.07
1.3
1.4
2.92
21.72
e6/l
5.06
87
593
45
238
1.90
4.01
2.5
2.5
—
—
—
0
0
1349
12314
1.15
4.00
2.5
2.4
—
—
—
0
0
16
53
3.03
3.96
2.8
4.7
1.53
1.26
%
0.19
16
53
134
942
1.44
3.90
1.2
1.2
228.62
242.48
u/ml
0.27
78
621
1392
12771
1.14
3.78
2.0
1.9
—
—
—
0
0
103
694
1.50
3.73
3.9
3.4
1.35
1.19
mg/l
1.63
98
641
212
1621
1.33
3.72
1.7
1.7
13.84
9.32
u/ml
0.75
47
469
137
977
1.42
3.71
7.1
9.0
0.64
0.68
%
0.47
137
970
837
7411
1.17
3.70
2.0
2.0
—
—
—
0
0
574
4925
1.20
3.69
1.6
1.6
1.39
1.32
%
3.24
524
4453
1237
11278
1.15
3.66
2.3
2.3
—
—
—
0
0
140
1005
1.41
3.65
7.2
8.8
1.32
1.32
%
0.00
140
997
119
831
1.45
3.62
1.3
1.3
150.59
147.17
au/ml
0.09
24
215
79
506
1.57
3.61
1.4
1.3
—
—
—
0
0
29
136
2.14
3.60
1.1
1.4
140.21
143.51
mmol/24h
0.10
29
136
183
1378
1.35
3.57
1.6
1.5
—
—
—
0
0
44
241
1.84
3.56
2.7
2.6
664.09
512.31
e6/l
1.91
35
190
20
80
2.51
3.54
1.5
1.3
—
—
—
0
0
20
80
2.51
3.54
1.5
1.3
—
—
—
0
0
87
574
1.53
3.50
2.5
2.0
206.41
262.47
ug/l
0.23
69
512
153
1124
1.38
3.50
2.6
2.4
176.06
164.38
%
0.95
144
1062
55
325
1.70
3.46
3.6
3.2
33.72
44.22
mg/l
0.36
50
288
127
910
1.41
3.38
2.1
1.9
—
—
—
0
0
41
224
1.84
3.36
1.0
1.1
—
0.64
—
0
5
67
421
1.60
3.34
1.1
1.1
190.70
197.14
mg/l
0.23
61
373
118
837
1.42
3.32
2.3
2.2
1.49
1.26
g/l
1.66
108
728
63
392
1.62
3.28
2.3
1.8
17.01
16.95
%
0.07
63
386
195
1505
1.31
3.24
3.1
3.8
7.49
35.92
ug/l
0.60
136
1065
530
4568
1.19
3.24
2.6
2.4
0.87
1.18
e6/l
1.23
248
2223
69
445
1.56
3.11
1.5
1.4
—
—
—
0
0
239
1906
1.27
3.10
2.8
2.2
78.20
83.28
ml/min/173m2
1.16
101
754
45
261
1.73
3.06
5.8
4.8
9.43
6.41
mmol/l
0.51
39
214
79
528
1.51
3.04
2.5
1.9
132.15
131.33
g/l
0.17
71
436
135
997
1.37
3.03
1.4
1.3
21.35
43.37
u/ml
1.52
14
86
55
338
1.64
3.03
2.1
1.5
—
—
—
0
0
67
435
1.55
2.95
1.1
1.1
34.21
35.59
mg/l
0.17
58
364
47
281
1.68
2.89
3.2
3.2
1.21
1.98
ratio
1.45
30
159
348
2921
1.21
2.85
1.1
1.1
—
—
—
0
0
51
315
1.63
2.78
1.5
1.3
—
—
—
0
0
269
2207
1.24
2.76
2.8
2.3
—
—
—
0
0
50
309
1.63
2.73
1.3
1.2
—
—
—
0
0
7
14
5.01
2.72
1.0
1.1
—
—
—
0
0
19
85
2.24
2.70
1.9
2.3
—
—
—
0
0
61
397
1.55
2.69
1.1
1.1
—
—
—
0
0
32
176
1.83
2.63
2.5
2.6
14.60
14.89
index
0.06
15
118
237
1930
1.24
2.62
1.6
1.7
4.63
4.16
mg/l
0.39
192
1356
313
2628
1.21
2.58
2.5
2.4
16.79
18.78
au/ml
0.26
44
377
51
322
1.59
2.57
1.4
1.6
—
—
—
0
0
484
4237
1.16
2.46
2.9
2.5
5.30
5.24
e6/l
0.03
202
1876
45
279
1.62
2.45
1.1
1.2
132.38
117.80
pmol/l
1.20
45
279
294
2467
1.21
2.45
1.3
1.3
47.45
35.15
au/ml
0.43
17
127
7
17
4.12
2.36
1.3
2.3
—
—
—
0
0
95
697
1.37
2.30
1.2
1.2
2.78
3.59
u/ml
0.64
37
314
103
766
1.35
2.30
1.1
1.1
2.92
2.79
eliau/ml
0.05
50
431
8
23
3.48
2.27
2.3
1.6
—
—
—
0
0
33
193
1.72
2.26
1.9
2.9
1684.00
717.09
u/ml
1.16
33
193
28
156
1.80
2.25
2.0
2.3
33.11
28.03
%
1.40
28
151
156
1234
1.28
2.25
2.3
2.1
0.24
0.22
g/l
2.24
149
1179
17
79
2.16
2.24
1.8
1.2
—
—
—
0
0
38
232
1.64
2.23
2.4
3.9
24.80
1283.59
u/ml
0.63
31
215
18
86
2.10
2.22
1.0
1.1
—
—
—
0
0
51
335
1.53
2.21
1.1
1.1
1442.38
1477.93
miu/ml
0.08
51
335
80
575
1.40
2.20
1.2
1.1
—
—
—
0
0
33
195
1.70
2.18
3.3
3.1
0.93
0.81
e9/l
0.52
33
189
8
24
3.34
2.18
1.1
1.2
1.27
1.38
umol/24h
—
8
24
79
569
1.40
2.16
3.6
3.2
16.32
22.62
mg/l
0.92
49
365
14
61
2.30
2.14
3.0
2.2
0.62
0.62
mmol/l
0.00
14
61
12
49
2.45
2.10
2.1
1.5
1.39
1.28
umol/l
1.01
12
32
137
1077
1.28
2.09
2.1
1.9
6.15
4.67
ug/l
0.32
122
933
5
10
5.01
2.07
1.0
1.2
—
—
—
0
0
5
10
5.01
2.07
1.0
1.0
—
—
—
0
0
26
146
1.79
2.06
1.0
1.3
—
—
—
0
0
8
26
3.08
2.01
1.9
2.1
—
—
—
0
0
31
185
1.68
2.00
2.1
1.5
4.84
5.07
u/l
0.12
23
159
46
303
1.52
2.00
1.0
1.1
1.32
1.01
u/l
0.54
21
105
29
170
1.71
2.00
3.8
2.2
—
—
—
0
0
158
1273
1.25
1.99
2.3
2.1
1.25
1.17
g/l
2.50
151
1217
40
256
1.57
1.97
1.1
1.1
—
—
—
0
0
16
77
2.08
1.96
3.1
1.6
—
—
—
0
0
16
77
2.08
1.96
3.1
1.6
—
—
—
0
0
16
77
2.08
1.96
3.1
1.6
—
—
—
0
0
20
105
1.91
1.95
1.5
1.5
3.19
6.69
u/l
1.22
14
90
18
91
1.98
1.95
2.8
3.3
63.04
99.45
ng/l
0.36
12
54
9
34
2.65
1.86
1.2
1.1
85.33
91.29
titre
—
9
34
5
12
4.17
1.82
1.0
1.1
4.20
29.25
u/l
—
5
12
59
419
1.41
1.79
3.4
4.1
3.73
3.74
mmol/l
0.03
59
414
87
659
1.33
1.79
2.8
2.4
1.56
1.79
index
0.14
43
350
89
679
1.32
1.75
1.1
1.1
—
—
—
0
0
11
48
2.30
1.70
1.1
1.4
—
—
—
0
0
20
111
1.81
1.68
2.8
1.5
—
—
—
0
0
20
111
1.81
1.68
2.8
1.5
—
—
—
0
0
20
111
1.81
1.68
2.8
1.5
—
—
—
0
0
20
111
1.81
1.68
2.8
1.5
—
—
—
0
0
31
195
1.59
1.68
1.1
1.2
107.29
96.18
%
1.11
14
78
101
795
1.28
1.60
1.7
1.6
7.22
6.59
mmol/l
1.28
94
734
6
20
3.00
1.58
1.0
1.5
—
—
—
0
0
95
744
1.28
1.57
1.2
1.2
3.06
3.13
u/ml
0.01
33
296
11
50
2.20
1.57
1.4
1.2
—
—
—
0
0
19
324
0.58
1.56
1.1
1.2
52.95
67.97
ug/l
0.88
19
324
17
92
1.85
1.55
1.1
1.1
—
—
—
0
0
31
200
1.55
1.53
1.2
1.1
101.92
94.96
%
0.82
13
77
32
209
1.54
1.51
1.3
1.2
110.00
201.46
titre
—
5
41
15
79
1.90
1.49
1.0
1.0
0.01
0.09
u/ml
—
6
35
49
351
1.40
1.47
1.2
1.2
0.60
0.69
ratio
0.81
30
212
346
3082
1.14
1.45
1.5
1.5
57.05
59.94
ug/l
0.54
346
3082
596
5478
1.10
1.44
1.4
1.5
—
—
—
0
0
25
157
1.60
1.40
1.4
1.2
—
—
—
0
0
63
475
1.33
1.40
1.4
1.5
—
—
—
0
0
100
803
1.25
1.38
2.4
2.2
13.21
13.07
%
0.65
100
796
153
1285
1.20
1.38
1.5
1.6
18.57
0.43
iu/ml
0.47
19
191
24
150
1.60
1.37
1.8
2.4
15.62
14.72
umol/l
0.13
24
150
38
264
1.44
1.36
1.0
1.1
—
—
—
0
0
395
3575
1.12
1.29
2.1
1.8
—
—
—
0
0
5
18
2.78
1.28
1.0
1.1
—
—
—
0
0
19
114
1.67
1.28
2.3
1.6
—
—
—
0
0
184
1587
1.17
1.24
1.7
1.6
—
—
—
0
0
6
25
2.40
1.24
1.2
1.6
539.90
544.86
nmol/l
—
6
25
28
410
0.68
1.23
1.0
1.1
10.74
12.85
u/ml
0.19
12
198
8
37
2.16
1.21
2.8
1.6
—
—
—
0
0
66
514
1.29
1.20
2.5
3.4
495.82
406.20
u/ml
0.06
60
437
45
332
1.36
1.18
1.1
1.2
1.62
1.54
u/ml
0.03
28
155
18
110
1.64
1.15
1.0
1.0
—
—
—
0
0
116
969
1.20
1.15
1.1
1.1
—
—
—
0
0
14
80
1.75
1.12
1.0
1.0
0.01
0.02
u/ml
—
7
37
11
58
1.90
1.12
6.0
3.3
4.49
4.44
kpa
0.05
11
58
11
58
1.90
1.12
6.0
3.3
10.78
11.65
kpa
0.43
11
58
51
388
1.32
1.11
1.2
1.1
11.64
7.01
iu/ml
0.55
18
110
20
127
1.58
1.11
1.1
1.1
—
0.10
—
0
5
90
736
1.23
1.11
2.7
2.8
23.83
28.36
iu/ml
—
6
28
156
1343
1.17
1.11
2.9
2.5
1.02
1.02
ratio
0.43
128
1144
78
629
1.25
1.09
1.5
1.4
—
3613.33
—
0
6
36
260
1.39
1.09
2.0
1.7
19.42
23.16
mg/l
0.26
12
99
63
496
1.27
1.08
2.1
1.9
0.42
0.31
g/l
0.13
56
449
172
1500
1.15
1.04
1.4
1.3
—
—
—
0
0
58
456
1.28
1.02
1.6
1.7
5091.98
8346.13
e6/l
0.94
40
334
15
91
1.65
1.00
1.2
1.1
—
—
—
0
0
44
334
1.32
1.00
1.6
1.6
—
—
—
0
0
25
172
1.46
0.99
1.2
1.2
110.68
108.14
%
0.22
25
152
114
967
1.18
0.99
1.1
1.1
—
—
—
0
0
167
1903
0.87
0.98
1.1
1.1
0.66
0.57
ratio
1.07
14
176
57
450
1.27
0.98
1.6
1.7
0.00
0.00
g/l
0.50
51
417
48
371
1.30
0.97
5.4
6.0
338.97
369.59
umol/l
0.60
42
319
9
50
1.80
0.96
2.1
1.4
—
—
—
0
0
56
443
1.27
0.95
1.0
1.0
—
—
—
0
0
279
2529
1.11
0.94
1.7
1.5
—
—
—
0
0
36
268
1.35
0.94
2.0
2.3
22.54
24.75
mg/l
0.16
26
182
13
78
1.67
0.91
1.1
1.1
—
—
—
0
0
13
78
1.67
0.91
1.0
1.1
0.02
0.59
u/ml
—
6
40
71
581
1.23
0.91
1.3
1.2
—
—
—
0
0
3013
29740
1.07
0.91
17.9
13.2
331.85
332.22
g/l
1.52
2999
29580
182
1617
1.13
0.88
1.8
1.6
0.28
0.24
mg/l
0.39
60
617
7
127
0.55
0.88
1.6
2.3
128.29
164.42
nmol/l
—
7
114
8
43
1.86
0.87
1.8
1.7
—
—
—
0
0
20
136
1.47
0.86
1.4
1.7
2.66
2.47
mg/l
0.27
20
130
54
432
1.25
0.86
1.6
1.7
0.00
0.00
g/l
-0.00
48
389
16
104
1.54
0.84
2.1
6.2
—
381.14
—
0
14
69
572
1.21
0.81
1.6
1.5
—
—
—
0
0
8
47
1.70
0.80
1.9
1.6
—
—
—
0
0
32
241
1.33
0.80
1.1
1.1
4.73
15.15
u/ml
4.65
17
171
26
190
1.37
0.78
7.0
7.7
14.99
101.10
ug/l
0.49
19
125
19
131
1.45
0.78
1.0
1.2
116.84
103.26
%
1.46
19
126
26
191
1.36
0.77
1.5
1.5
—
—
—
0
0
24
174
1.38
0.76
1.6
2.4
8.35
9.77
mg/l
0.63
18
151
33
252
1.31
0.76
18.7
16.5
833.76
5938.21
nmol/l
0.50
33
244
34
261
1.31
0.76
1.5
1.5
—
—
—
0
0
176
1955
0.90
0.74
1.1
1.1
1.51
1.58
g/l
3.25
176
1955
7
38
1.84
0.73
1.1
1.0
—
—
—
0
0
9
55
1.64
0.73
1.6
1.1
—
—
—
0
0
51
415
1.23
0.73
1.2
1.2
—
—
—
0
0
15
100
1.50
0.72
1.0
1.1
3.71
6.71
u/ml
0.64
15
100
30
228
1.32
0.72
1.2
1.2
—
—
—
0
0
33
255
1.30
0.71
1.5
1.4
—
—
—
0
0
7
40
1.75
0.71
1.0
1.1
—
—
—
0
0
22
160
1.38
0.70
1.5
1.5
7247.27
74173.07
e6/l
0.83
15
98
15
101
1.49
0.70
1.5
1.4
30287.40
2213.45
e6/l
—
10
64
7
41
1.71
0.70
1.0
1.0
—
—
—
0
0
7
41
1.71
0.70
1.3
1.1
419.86
341.03
pmol/l
—
7
29
23
169
1.36
0.69
4.4
4.2
300.62
179.84
umol/l
0.70
13
92
13
85
1.53
0.69
1.1
1.1
—
—
—
0
0
45
367
1.23
0.65
1.2
1.2
—
—
—
0
0
44
359
1.23
0.63
1.2
1.2
—
—
—
0
0
12
79
1.52
0.62
1.0
1.1
—
—
—
0
0
44
360
1.22
0.62
1.2
1.2
—
—
—
0
0
8
50
1.60
0.61
4.2
4.1
—
—
—
0
0
19
139
1.37
0.60
1.0
1.0
—
—
—
0
0
8
52
1.54
0.59
1.0
1.0
17.42
21.59
u/ml
—
8
41
36
290
1.24
0.59
1.2
1.6
—
—
—
0
0
2993
29641
1.05
0.59
4.4
4.1
—
—
—
0
0
33
266
1.24
0.55
25.9
22.4
1546.15
5031.82
nmol/l
0.48
33
256
42
348
1.21
0.55
1.1
1.2
—
—
—
0
0
80
910
0.88
0.54
1.1
1.1
0.10
0.22
u/ml
1.05
25
249
34
276
1.23
0.54
1.8
1.6
—
—
—
0
0
32
258
1.24
0.53
1.4
1.2
9.75
8.48
mm/h
0.30
32
258
6
39
1.54
0.53
1.0
1.2
—
—
—
0
0
9
134
0.67
0.51
1.0
1.1
0.87
1.26
mom
—
9
134
859
8315
1.04
0.51
1.5
1.6
897.70
1006.50
mu/l
3.65
744
7134
159
1461
1.09
0.49
1.1
1.1
1.99
2.50
u/ml
0.41
88
764
7
46
1.52
0.48
1.1
1.0
—
—
—
0
0
24
190
1.26
0.48
1.3
1.3
0.32
0.28
g/l
1.00
19
154
16
120
1.33
0.46
4.9
4.1
—
—
—
0
0
58
663
0.87
0.45
1.2
1.2
247.17
2043.02
pmol/l
—
6
61
7
50
1.40
0.45
1.0
1.0
0.00
0.08
u/ml
—
7
50
24
192
1.25
0.44
1.4
1.7
144.42
130.51
%
0.36
24
180
16
121
1.32
0.44
1.1
1.0
53.09
32.53
iu/ml
0.36
16
121
13
95
1.37
0.43
1.8
1.3
5.92
5.39
mmol/l
0.73
13
95
277
2620
1.06
0.42
1.5
1.5
—
—
—
0
0
8
61
1.31
0.39
1.5
1.8
—
112.06
—
0
18
17
133
1.28
0.38
1.0
1.1
0.44
1.47
u/ml
—
9
85
10
136
0.73
0.37
2.8
2.7
—
—
—
0
0
119
1098
1.09
0.37
1.1
1.1
4.61
5.49
u/ml
0.21
68
554
40
346
1.16
0.36
1.2
1.2
—
—
—
0
0
9
70
1.29
0.36
1.0
1.0
—
—
—
0
0
82
901
0.91
0.36
1.2
1.1
27.29
14.33
au/ml
0.74
28
266
28
236
1.19
0.34
1.4
1.3
—
—
—
0
0
540
5575
0.96
0.34
1.6
1.6
3.47
3.20
ratio
5.54
373
3918
420
4358
0.96
0.34
1.4
1.5
3.47
3.34
mmol/l
1.49
263
2797
26
218
1.19
0.34
1.2
1.7
—
2048617.55
—
0
22
33
284
1.16
0.33
2.4
2.3
6.83
6.97
mmol/l
0.13
33
279
27
230
1.18
0.31
1.7
1.7
47.00
46.28
%
0.03
17
136
21
175
1.20
0.30
1.0
1.1
—
—
—
0
0
7
55
1.27
0.30
1.0
1.1
—
—
—
0
0
20
166
1.21
0.29
1.5
1.7
43.69
46.02
%
0.09
14
97
32
278
1.15
0.29
1.4
1.5
—
—
—
0
0
10
76
1.32
0.28
1.0
1.2
—
—
—
0
0
8
65
1.23
0.27
1.0
1.1
—
—
—
0
0
13
160
0.81
0.26
1.4
1.1
—
—
—
0
0
402
3902
1.03
0.25
1.6
1.6
—
—
—
0
0
18
151
1.19
0.25
1.2
1.2
—
—
—
0
0
9
75
1.20
0.25
1.0
1.1
—
—
—
0
0
12
148
0.81
0.24
1.2
1.5
3.67
3.28
u/field
—
6
106
59
543
1.09
0.23
1.5
1.9
—
—
—
0
0
5
38
1.32
0.23
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
12
145
0.83
0.21
1.7
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
21
183
1.15
0.20
1.8
1.2
67.76
66.29
umol/l
0.08
21
183
6
49
1.22
0.20
1.0
1.9
43.07
42.30
g/l
—
6
49
130
1240
1.05
0.20
1.1
1.1
1.05
1.95
u/ml
1.67
77
626
288
2795
1.03
0.20
1.4
1.4
—
—
—
0
0
6
50
1.20
0.19
1.2
1.1
—
—
—
0
0
44
479
0.92
0.19
1.8
1.5
0.52
0.49
e9/l
0.22
44
479
305
2970
1.03
0.18
1.4
1.4
216.97
239.52
miu/ml
0.58
155
1569
7
60
1.17
0.17
1.0
1.0
0.04
0.51
u/ml
—
7
47
7
61
1.15
0.17
1.7
1.2
1.21
1.19
mmol/l
—
7
61
12
142
0.84
0.17
1.2
1.4
—
—
—
0
0
98
1029
0.95
0.17
1.1
1.1
3.56
5.99
u/ml
1.35
48
465
8
69
1.16
0.16
1.3
1.3
—
—
—
0
0
111
1062
1.05
0.16
1.4
1.3
—
—
—
0
0
16
139
1.15
0.16
1.2
1.1
—
—
—
0
0
446
4374
1.02
0.16
1.5
1.5
1.14
1.15
ratio
0.12
264
2648
6
77
0.78
0.15
1.3
1.6
—
—
—
0
0
6
77
0.78
0.15
1.3
1.6
—
—
—
0
0
29
317
0.91
0.15
2.0
2.0
—
—
—
0
0
11
129
0.85
0.14
1.2
1.3
—
—
—
0
0
7
90
0.78
0.14
1.6
1.6
61.09
75.36
ng/l
—
7
90
10
84
1.19
0.14
1.0
1.1
—
—
—
0
0
39
363
1.08
0.13
1.2
1.4
—
—
—
0
0
241
2468
0.97
0.13
1.2
1.3
—
—
—
0
0
446
4391
1.02
0.12
1.5
1.5
1.15
1.19
ratio
0.55
266
2683
446
4391
1.02
0.12
1.5
1.5
1.02
0.95
ratio
1.77
264
2665
131
1269
1.03
0.12
1.1
1.1
2.62
6.22
u/ml
5.41
66
709
459
4659
0.98
0.12
1.5
1.5
60.11
61.96
ug/l
0.32
383
3957
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
18
162
1.11
0.11
1.0
1.1
—
—
—
0
0
122
1182
1.03
0.11
1.3
1.2
5.39
4.60
0.21
14
195
11
126
0.87
0.11
1.2
1.3
—
—
—
0
0
26
240
1.08
0.11
1.2
1.2
—
—
—
0
0
10
86
1.16
0.11
1.1
1.2
—
—
—
0
0
10
115
0.87
0.10
1.2
1.1
—
—
—
0
0
178
1819
0.98
0.09
2.2
2.2
—
—
—
0
0
5
48
1.04
0.09
1.0
1.0
—
—
—
0
0
16
146
1.10
0.08
1.8
1.9
3.74
3.90
mmol/l
1.22
16
146
16
146
1.10
0.08
1.8
1.9
105.38
106.15
mmol/l
0.20
16
146
13
143
0.91
0.07
1.2
1.7
—
—
—
0
0
9
84
1.07
0.07
1.0
1.1
—
—
—
0
0
9
86
1.05
0.07
1.0
1.1
—
—
—
0
0
50
514
0.97
0.04
1.5
2.2
—
—
—
0
0
433
4304
1.01
0.04
1.5
1.5
—
—
—
0
0
112
1136
0.99
0.03
1.4
1.6
—
—
—
0
0
18
171
1.05
0.03
1.5
2.7
20.56
179.05
ug/l
0.73
18
161
11
118
0.93
0.02
1.2
1.3
—
—
—
0
0
11
117
0.94
0.01
1.2
1.1
100.09
94.05
%
0.52
11
117
69
682
1.01
0.01
1.2
1.2
—
—
—
0
0
17
176
0.97
0.00
1.3
1.8
1.17
2.20
u/field
—
6
103
14
142
0.99
0.00
1.2
1.1
—
—
—
0
0
88
882
1.00
0.00
1.9
1.9
—
—
—
0
0
121
1205
1.00
0.00
1.1
1.1
0.49
1.17
u/ml
2.02
46
526
11
111
0.99
0.00
1.2
1.1
5.20
4.92
mg/g
0.16
11
111
12
119
1.01
0.00
1.1
1.1
—
—
—
0
0
14
141
0.99
0.00
1.9
1.9
1.21
1.20
mmol/l
0.35
14
141
0
8
0.00
0.00
0.0
1.0
—
32.89
—
0
8
0
8
0.00
0.00
0.0
1.0
—
21.24
—
0
8
8
82
0.98
0.00
1.8
1.6
9.28
8.15
ug/l
—
8
82
0
8
0.00
0.00
0.0
1.0
—
9.61
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
31
310
1.00
-0.00
1.4
1.8
8.42
1.86
u/ml
—
7
94
0
7
0.00
-0.00
0.0
1.0
—
4.43
—
0
7
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
59
0.85
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_OVARDYS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_OVARDYS | 1.99 [1.65, 2.4] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.284 |
During the follow-up period (1.1.1998 — 31.12.2019), 243 out of 12980 females with E4_OVARDYS died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have E4_OVARDYS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.18% | No data |
| 5 | 1.088% | No data |
| 10 | 2.691% | No data |
| 15 | 5.534% | No data |
| 20 | 10.04% | No data |
Relationships between endpoints
↥Index endpoint: E4_OVARDYS – Ovarian dysfunction
GWS hits: 8
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data