Ovarian dysfunction, other/unspecified

E4_OVARDYSNAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E28.8, E28.9
  • Hospital discharge: ICD-9 256[8-9]
  • Hospital discharge: ICD-8 2569
  • Hospital discharge: excluded ICD-8 25690
  • Cause of death: ICD-10 E28.8, E28.9
  • Cause of death: ICD-9 256[8-9]
  • Cause of death: ICD-8 2569
  • Cause of death: excluded ICD-8 25690

2 out of 7 registries used, show all original rules.

269

4. Check minimum number of events

None

269

5. Include endpoints

None

269

6. Filter based on genotype QC (FinnGen only)

224

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1225 1225 -
Only index persons 1157 1157 -
Unadjusted period prevalence (%)
Whole population 0.04 0.04 -
Only index persons 0.04 0.04 -
Median age at first event (years)
Whole population - 32.36 -
Only index persons - 31.95 -

-FinnGen-

Key figures

All Female Male
Number of individuals 224 224 -
Unadjusted period prevalence (%) 0.08 0.08 -
Median age at first event (years) 33.79 33.79 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
234
Matched controls
2340
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E28.8
ICD-10 Finland
Other ovarian dysfunction
+∞
130.9
113
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
63.3
123.9
71
16
E28.9
ICD-10 Finland
Ovarian dysfunction, unspecified
+∞
65.8
60
*
G03FB08
ATC
dydrogesterone and estrogen; systemic
10.4
47.1
60
75
E28.3
ICD-10 Finland
Primary ovarian failure
504.4
43.7
42
*
N91.1
ICD-10 Finland
Secondary amenorrhoea
13.1
32.5
33
29
25691, ,
ICD-8 Finland
+∞
23.3
22
*
25699
ICD-8 Finland
Ovarian dysfunction, Other and unspecified
+∞
20.1
19
*
25698
ICD-8 Finland
Ovarian dysfunction, Alia definita
+∞
19.0
18
*
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
3.4
17.8
159
892
N97.8
ICD-10 Finland
Female infertility of other origin
8.1
17.7
25
34
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.9
14.4
140
790
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
26.0
12.7
17
7
H02AB09
ATC
hydrocortisone; systemic
14.9
11.2
18
13
E89.4
ICD-10 Finland
Postprocedural ovarian failure
115.0
10.5
11
*
G03DB01
ATC
dydrogesterone; oral
2.9
10.4
61
256
62800
ICD-8 Finland
Sterility, female, Sterilitas primaria
19.9
10.4
15
8
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
9.7
90
473
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
18.5
9.5
14
8
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
9.4
9
*
H01CA02
ATC
nafarelin; nasal
4.6
8.6
21
49
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
8.4
8.5
18
23
G03GA02
ATC
human menopausal gonadotrophin; parenteral
4.6
8.1
20
47
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.1
7.7
22
58
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
7.3
7
*
A02BC05
ATC
esomeprazole; systemic
2.1
7.0
103
637
N97.9
ICD-10 Finland
Female infertility, unspecified
3.0
6.9
32
117
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
17.3
6.8
10
6
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
41.3
6.8
8
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
6.6
53
255
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.5
6.6
24
75
N97.0
ICD-10 Finland
Female infertility associated with anovulation
6.5
6.6
16
26
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
6.5
38
157
G03FA14
ATC
dydrogesterone and estrogen; systemic
3.2
6.5
27
92
H02AA02
ATC
fludrocortisone; oral
71.7
6.5
7
*
G03DA02
ATC
medroxyprogesterone; systemic
2.8
6.4
33
128
XW000
NOMESCO Finland
Bone marrow biopsy
7.4
6.3
14
20
9663/3-C77.9
ICD-O-3
Hodgkin lymphoma, nodular sclerosis, NOS, of lymph node, NOS
+∞
6.3
6
*
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
6.3
6
*
2568X
ICD-9 Finland
Ovarian dysfunction, Other ovarian dysfunction
+∞
6.3
6
*
H01AC01
ATC
somatropin; parenteral
+∞
6.3
6
*
W12
ICPC
Contraception intrauterine
0.2
6.3
9
338
N91.2
ICD-10 Finland
Amenorrhoea, unspecified
13.0
6.1
10
8
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
4.1
6.1
17
44
H02AB06
ATC
prednisolone; systemic
2.0
6.1
114
760
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.0
6.0
28
102

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
57
75
9.73
42.79
1.5
1.2
19.91
8.99
u/l
4.20
46
64
50
77
7.99
32.53
1.6
1.2
2.22
2.65
ug/l
0.30
30
71
44
66
7.98
29.16
1.5
1.4
0.27
0.48
nmol/l
1.45
30
55
62
220
3.47
14.46
2.1
1.3
31.68
20.17
iu/l
1.62
54
191
18
13
14.88
11.17
1.0
1.0
—
—
—
0
0
94
552
2.17
7.42
6.1
3.3
7.39
7.40
ph
0.37
73
373
89
522
2.14
6.96
3.6
3.0
0.22
0.38
e6/l
0.77
64
363
74
404
2.22
6.93
7.5
3.6
—
—
—
0
0
65
343
2.24
6.57
3.9
2.7
504.52
515.12
mosm/kgh2o
0.16
60
297
47
216
2.47
6.50
1.4
1.4
—
—
—
0
0
21
61
3.68
6.45
1.9
1.4
30.51
20.02
u/l
0.87
21
51
47
217
2.46
6.43
2.3
1.5
—
—
—
0
0
110
714
2.02
6.43
7.0
7.6
1.09
1.09
inr
0.01
88
572
104
674
1.98
6.00
8.8
5.3
—
—
—
0
0
139
996
1.97
5.97
9.3
5.4
2.61
2.70
%
0.20
133
927
115
775
1.95
5.89
6.3
4.0
35.75
37.02
g/l
1.25
109
733
138
994
1.95
5.75
9.4
5.4
0.69
0.68
%
0.05
132
921
138
999
1.93
5.61
9.5
5.5
8.35
8.20
%
0.27
132
934
17
47
3.82
5.59
3.4
3.0
54.65
60.49
%
0.98
17
47
136
983
1.92
5.52
13.2
9.2
0.00
0.00
e9/l
0.75
113
793
114
782
1.89
5.40
7.7
5.0
1.21
1.22
mmol/l
1.10
109
723
158
1208
1.95
5.33
14.3
8.8
3.82
3.91
e9/l
0.17
137
1046
94
608
1.91
5.31
3.9
3.1
33.28
58.17
e6/l
0.68
69
435
28
110
2.76
5.27
3.9
3.1
61.29
73.71
e9/l
0.81
19
74
145
1086
1.88
5.11
9.4
5.6
0.04
0.04
e9/l
0.37
130
931
91
589
1.89
5.09
2.4
3.0
12.52
20.78
ng/l
1.73
44
307
138
1021
1.86
5.02
8.8
5.4
56.77
56.82
%
0.01
133
970
150
1142
1.87
4.95
9.8
5.9
0.17
0.17
e9/l
0.15
138
991
144
1084
1.85
4.91
9.5
5.6
0.50
0.52
e9/l
0.42
129
932
145
1096
1.85
4.86
5.5
4.0
6.44
6.26
mmol/l
0.51
138
984
138
1031
1.83
4.77
9.5
5.4
29.21
29.43
%
0.08
133
979
109
760
1.81
4.72
4.9
3.8
23.88
46.80
e6/l
1.55
71
477
147
1122
1.83
4.71
9.5
5.5
1.83
2.03
e9/l
1.06
135
991
15
43
3.66
4.70
2.0
1.3
462.00
330.97
mu/l
0.26
15
32
121
875
1.79
4.61
8.4
5.4
1.21
1.22
mmol/l
0.70
105
757
25
100
2.68
4.55
3.9
5.8
24.53
24.89
mmol/l
0.16
25
100
208
1799
2.41
4.47
6.4
4.8
14.54
14.37
pmol/l
0.50
197
1675
60
351
1.95
4.47
1.7
1.5
504.00
576.71
titre
—
10
79
34
160
2.32
4.42
3.3
3.0
1.79
1.86
%
0.13
34
139
45
239
2.09
4.36
2.6
2.0
—
—
—
0
0
14
34
4.31
4.29
3.8
3.1
3.62
4.83
e9/l
1.15
14
34
15
39
4.04
4.28
3.5
2.4
7.40
7.43
ph
1.02
15
39
12
25
5.00
4.25
2.3
1.6
—
—
—
0
0
12
25
5.00
4.25
2.3
1.6
—
—
—
0
0
12
25
5.00
4.25
2.3
1.6
—
—
—
0
0
12
25
5.00
4.25
2.3
1.6
—
—
—
0
0
83
548
1.80
4.21
6.8
4.1
—
—
—
0
0
90
612
1.76
4.11
8.4
6.2
—
—
—
0
0
31
145
2.31
4.09
3.8
4.6
1.00
0.63
%
—
8
35
31
148
2.26
3.90
4.3
4.8
0.94
0.65
%
—
9
37
9
15
6.19
3.85
1.4
1.3
—
—
nmol/l
—
0
0
30
142
2.28
3.85
4.1
4.9
0.25
0.10
%
—
8
30
94
658
1.72
3.82
4.0
2.9
2.35
2.35
mmol/l
0.07
82
601
51
300
1.90
3.69
3.0
2.9
4.49
4.58
e6/l
0.02
17
124
56
344
1.83
3.53
1.7
1.5
—
—
—
0
0
10
22
4.70
3.47
1.5
1.0
—
—
—
0
0
7
10
7.18
3.38
2.4
3.2
1606.71
512.60
u/ml
—
7
10
119
908
1.63
3.36
2.3
2.0
—
—
—
0
0
6
7
8.76
3.28
1.2
1.3
2.82
2.47
mg/l
—
6
7
28
138
2.17
3.27
1.3
1.1
—
—
—
0
0
26
126
2.20
3.17
4.2
7.4
—
—
—
0
0
14
50
2.91
3.14
1.4
1.4
—
—
—
0
0
11
30
3.79
3.13
1.4
1.4
—
—
—
0
0
29
148
2.10
3.11
3.6
5.3
0.00
0.17
%
—
6
30
96
708
1.60
3.04
3.8
2.0
—
—
—
0
0
111
848
1.59
3.03
2.0
1.9
87.47
97.47
pmol/l
1.14
51
450
120
935
1.58
3.00
4.4
3.2
6.42
6.25
ph
0.94
70
516
33
181
1.96
2.92
3.9
3.7
—
—
—
0
0
9
22
4.21
2.91
2.2
2.0
—
—
—
0
0
39
229
1.84
2.82
3.7
2.4
4.50
5.29
umol/l
0.46
34
193
127
1012
1.56
2.81
3.6
2.4
76.03
75.96
nmol/l
0.01
121
933
9
23
4.03
2.80
1.4
1.3
—
—
—
0
0
220
2029
2.41
2.72
7.4
5.8
1.69
1.73
mu/l
0.25
212
1928
14
55
2.64
2.67
1.9
1.1
2.33
15.53
e6/l
—
9
38
32
180
1.90
2.64
1.8
1.3
217.15
244.62
u/ml
0.06
32
167
29
158
1.95
2.62
3.1
4.5
16.96
9.36
ug/l
0.21
18
125
28
151
1.97
2.61
1.8
2.9
7.39
7.39
ph
0.16
18
80
6
11
5.56
2.56
2.0
2.1
170.00
212.09
e6/l
—
6
11
40
245
1.76
2.53
1.4
1.3
125.26
187.26
u/ml
0.52
13
110
140
1158
1.52
2.50
4.8
3.6
0.00
0.00
estimate
0.50
32
242
24
125
2.03
2.46
4.8
3.5
1.23
1.23
mmol/l
0.07
24
108
9
27
3.42
2.42
2.3
2.3
9.68
9.43
kpa
—
9
27
9
27
3.42
2.42
2.4
2.3
4.96
4.90
kpa
—
9
27
5
8
6.36
2.38
1.2
1.8
14.18
13.00
umol/l
—
5
8
7
17
4.21
2.38
1.4
1.5
92.19
91.44
%
—
7
17
6
13
4.71
2.28
1.2
1.7
39.50
21.62
ng/l
—
6
13
140
1173
1.48
2.24
4.8
3.6
39.41
12.73
estimate
0.29
34
246
109
871
1.47
2.21
4.5
3.4
0.10
0.05
estimate
0.22
30
200
7
19
3.76
2.17
1.4
6.7
—
—
—
0
0
140
1179
1.47
2.14
5.0
3.7
0.00
0.01
estimate
0.50
32
234
12
49
2.53
2.14
1.8
2.2
2.43
1.36
index
—
7
25
38
241
1.69
2.13
3.1
1.8
29.06
28.85
s
0.07
38
236
47
316
1.61
2.11
3.5
3.1
92.19
192.04
ng/l
0.51
31
183
28
163
1.82
2.10
1.5
1.3
—
—
—
0
0
5
10
5.08
2.08
1.0
1.0
—
—
—
0
0
17
83
2.13
2.07
1.9
2.2
—
—
—
0
0
12
50
2.48
2.06
1.7
1.2
—
—
—
0
0
43
285
1.62
2.04
1.3
1.2
—
—
—
0
0
18
91
2.06
2.01
1.4
1.7
—
—
—
0
0
212
1966
1.83
1.99
4.5
4.2
1.55
1.55
mmol/l
0.03
205
1858
64
468
1.51
1.98
1.4
1.3
16.42
8.23
u/ml
0.32
19
176
72
540
1.48
1.97
1.6
1.6
18.35
22.54
nmol/l
1.63
67
472
201
1841
1.65
1.93
4.1
3.6
1.33
1.17
mmol/l
2.27
195
1729
226
2157
2.40
1.91
16.1
10.6
—
—
—
0
0
212
1972
1.80
1.88
4.7
4.2
4.79
4.76
mmol/l
0.14
205
1875
73
556
1.45
1.84
3.2
2.1
2.38
2.57
mg/l
0.37
65
477
221
2086
2.07
1.81
22.5
12.1
22.77
18.96
mg/l
0.98
190
1646
8
29
2.82
1.81
1.3
1.2
—
—
—
0
0
8
29
2.82
1.81
1.1
1.0
—
—
—
0
0
37
244
1.61
1.80
2.4
2.3
1708.99
6603.49
u/l
1.16
15
108
19
103
1.92
1.77
1.3
1.3
—
—
—
0
0
14
68
2.13
1.74
1.7
2.7
1.78
1.36
g/l
0.57
14
63
8
30
2.72
1.74
1.3
1.0
—
—
—
0
0
8
30
2.72
1.74
1.3
1.2
—
—
—
0
0
8
30
2.72
1.74
3.8
1.7
—
—
—
0
0
7
24
2.97
1.73
2.1
1.3
—
—
—
0
0
7
24
2.97
1.73
1.9
2.0
16.64
16.58
%
—
7
24
17
91
1.94
1.65
5.9
8.3
96.22
94.89
%
1.02
17
91
5
14
3.62
1.62
3.0
1.7
35.34
48.39
%
—
5
14
5
14
3.62
1.62
2.4
1.6
0.81
0.87
e9/l
—
5
14
66
505
1.43
1.60
3.4
3.4
1.01
1.02
kg/l
0.93
44
328
7
26
2.74
1.59
1.9
1.2
—
—
—
0
0
24
146
1.72
1.58
8.3
7.1
7.45
7.41
ph
—
10
83
17
93
1.89
1.56
1.5
2.9
24.84
24.57
mmol/l
0.14
17
93
66
508
1.42
1.55
1.4
1.4
29.23
15.17
iu/ml
0.87
15
143
66
509
1.41
1.53
2.5
1.8
1.11
1.00
mg/l
0.09
49
385
205
1912
1.58
1.51
5.0
4.1
5.61
5.61
mmol/l
0.02
196
1784
6
21
2.90
1.51
1.0
2.0
—
—
—
0
0
103
860
1.35
1.47
1.7
1.8
1.59
1.28
mmol/l
1.35
89
757
27
174
1.62
1.45
2.3
1.9
—
—
—
0
0
7
29
2.46
1.40
2.1
2.0
5.56
6.00
pmol/l
—
7
29
49
365
1.43
1.37
3.0
2.2
2.45
2.42
mmol/l
0.90
40
324
7
149
0.45
1.37
1.0
1.5
—
—
—
0
0
50
376
1.42
1.33
2.0
2.3
159.78
71.31
ug/g
1.02
39
290
40
289
1.46
1.31
1.2
1.2
—
—
—
0
0
11
55
2.05
1.29
4.4
3.6
1.08
1.21
mg/l
0.40
11
47
5
118
0.41
1.28
1.6
1.9
—
—
—
0
0
123
1073
1.31
1.23
4.0
2.6
—
—
estimate
—
0
0
24
352
0.65
1.22
1.5
1.6
1086.86
990.26
mu/l
0.15
15
291
210
1990
1.54
1.19
5.4
4.7
2.81
2.80
mmol/l
0.07
203
1884
11
57
1.98
1.19
4.6
3.3
36.95
36.91
°c
0.10
11
57
11
57
1.98
1.19
1.0
1.2
—
—
—
0
0
13
72
1.85
1.17
1.2
1.2
—
—
—
0
0
5
20
2.53
1.15
1.2
1.1
40.38
27.78
mg/l
—
5
15
74
607
1.32
1.15
4.2
3.8
0.03
0.01
estimate
0.33
30
233
81
673
1.31
1.14
2.8
2.7
—
—
—
0
0
59
468
1.35
1.14
3.0
3.2
36.98
57.63
mg/l
0.37
39
278
9
163
0.53
1.13
1.0
1.5
—
—
—
0
0
30
211
1.48
1.13
1.5
1.4
—
—
—
0
0
7
30
2.37
1.13
1.6
1.9
—
—
—
0
0
7
31
2.30
1.11
1.7
1.2
—
—
—
0
0
34
247
1.44
1.10
2.6
1.3
—
—
—
0
0
60
481
1.33
1.08
3.9
3.7
7.47
9.90
mg/mmol
0.20
35
265
14
82
1.75
1.07
2.1
2.2
0.75
0.56
%
1.41
14
82
20
130
1.59
1.06
3.9
2.2
1.80
0.18
e6/l
0.54
20
124
14
83
1.73
1.04
2.1
2.3
0.92
1.22
%
0.94
14
83
7
133
0.51
1.02
1.0
1.5
—
—
—
0
0
35
260
1.41
1.01
2.3
1.6
1373.32
1088.29
nmol/l
0.94
28
192
143
1295
1.27
0.98
4.0
3.2
80.01
63.05
ug/l
0.59
133
1227
5
23
2.20
0.98
1.2
1.0
—
—
—
0
0
9
51
1.79
0.95
1.2
2.5
—
—
—
0
0
7
37
1.92
0.95
8.1
5.8
1.30
1.06
mmol/l
—
7
31
6
28
2.17
0.92
1.2
1.2
—
—
—
0
0
14
87
1.65
0.90
1.4
2.0
2.70
4.30
ug/l
0.81
14
76
70
589
1.27
0.88
1.6
1.3
1.79
1.98
g/l
0.67
41
359
22
154
1.47
0.87
1.1
1.1
—
—
—
0
0
190
1795
1.31
0.85
5.9
4.9
38.62
37.13
mmol/mol
1.18
179
1703
10
164
0.59
0.83
1.0
1.5
—
—
—
0
0
10
163
0.60
0.82
1.0
1.5
—
—
—
0
0
10
58
1.76
0.81
2.2
1.2
4.27
3.59
mmol/l
—
10
51
10
162
0.60
0.80
1.0
1.5
—
—
—
0
0
92
807
1.23
0.80
1.7
1.8
—
—
—
0
0
13
83
1.60
0.76
1.4
1.9
—
—
—
0
0
7
39
1.82
0.73
5.7
3.7
—
—
—
0
0
5
25
2.02
0.73
1.4
1.3
—
—
—
0
0
31
240
1.34
0.72
1.6
1.3
—
—
—
0
0
24
178
1.39
0.72
2.9
2.4
31.92
16.92
au/ml
—
5
15
5
26
1.94
0.71
2.0
1.2
—
—
—
0
0
9
58
1.57
0.70
1.4
1.2
—
80.00
—
0
5
10
156
0.63
0.70
1.4
1.5
—
—
—
0
0
13
86
1.54
0.67
1.1
1.2
—
—
—
0
0
76
665
1.21
0.66
1.5
1.3
0.56
1.21
u/ml
1.45
25
168
11
162
0.66
0.61
1.4
1.6
—
—
—
0
0
30
238
1.30
0.60
1.2
1.1
—
—
—
0
0
6
38
1.59
0.54
1.0
1.2
—
—
—
0
0
65
571
1.19
0.54
2.9
2.9
6.97
7.88
mmol/l
0.85
53
484
155
1469
1.16
0.48
3.0
3.0
34.11
31.10
u/l
0.36
147
1409
19
147
1.32
0.47
1.1
1.1
—
—
—
0
0
76
685
1.16
0.47
4.6
2.9
0.10
0.03
estimate
0.30
30
195
49
559
0.84
0.45
1.8
1.8
—
—
—
0
0
9
130
0.68
0.44
1.1
1.1
—
—
—
0
0
18
228
0.77
0.43
1.5
1.7
3.44
3.32
mmol/l
0.21
12
153
6
95
0.62
0.43
1.2
1.4
—
0.21
—
0
37
10
70
1.45
0.42
1.3
1.1
—
—
—
0
0
5
33
1.53
0.41
1.4
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.3
—
122.34
—
0
17
8
61
1.32
0.40
2.3
3.9
—
—
—
0
0
9
68
1.34
0.38
1.2
1.2
—
—
—
0
0
36
414
0.85
0.37
1.4
1.6
—
—
—
0
0
37
321
1.18
0.36
1.8
2.0
—
—
—
0
0
189
1833
1.16
0.36
27.9
15.5
330.75
331.58
g/l
0.62
189
1825
6
43
1.41
0.35
1.2
1.0
—
—
—
0
0
80
739
1.13
0.34
2.2
2.2
—
—
—
0
0
7
56
1.26
0.29
3.6
3.5
27.21
32.76
u/ml
—
7
56
68
628
1.12
0.29
2.0
1.8
—
—
—
0
0
5
39
1.29
0.23
1.2
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
0.00
—
0
12
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
5
43
1.17
0.21
1.4
1.1
—
—
—
0
0
6
48
1.26
0.20
1.7
1.4
42.33
222.80
ug/l
—
6
41
6
50
1.21
0.20
2.8
1.5
0.30
1.87
ug/l
—
6
43
6
51
1.18
0.19
5.0
7.0
—
—
—
0
0
17
148
1.16
0.17
1.4
1.3
285.50
249.41
miu/ml
—
8
76
24
266
0.89
0.16
1.1
1.3
—
—
—
0
0
10
86
1.17
0.11
1.8
2.2
—
—
—
0
0
11
97
1.14
0.09
1.5
1.3
—
—
—
0
0
5
64
0.78
0.08
5.2
3.9
—
—
—
0
0
10
99
1.01
0.00
1.1
1.0
1.69
1.61
g/l
—
10
99
10
97
1.03
0.00
1.1
1.0
—
0.52
—
0
7
18
176
1.02
0.00
1.2
1.2
—
—
—
0
0
15
154
0.97
0.00
1.7
1.2
—
—
—
0
0
86
855
1.01
0.00
2.8
2.6
—
—
—
0
0
19
195
0.97
0.00
1.3
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
10.94
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
16.90
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
58
0.86
-0.00
1.2
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
6.50
—
0
8
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
0.02
—
0
8
0
8
0.00
-0.00
0.0
1.1
—
462.63
—
0
8
5
58
0.86
-0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
10
100
1.00
-0.00
1.1
1.0
0.85
0.85
g/l
—
10
100

Mortality – FinRegistry

Association

Association between endpoint E4_OVARDYSNAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_OVARDYSNAS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: E4_OVARDYSNAS – Ovarian dysfunction, other/unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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