primary ovarian insufficiency: Absent or premature cessation of ovarian function due to a pathologic process originating within the ovaries.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly females |
313377 |
2. Check conditionsNone |
313377 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
890 |
4. Check minimum number of eventsNone |
890 |
5. Include endpointsNone |
890 |
6. Filter based on genotype QC (FinnGen only) |
708 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E28
- Name in latin
- Insufficientia ovariorum primaria
Similar endpoints
↥List of similar endpoints to
Primary ovarian failure
based on the number of shared cases.
Similar with more cases:
- Ovarian dysfunction
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2798 | 2798 | - |
| Only index persons | 2690 | 2690 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | - |
| Only index persons | 0.10 | 0.10 | - |
| Median age at first event (years) | |||
| Whole population | - | 36.22 | - |
| Only index persons | - | 36.17 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 708 | 708 | - |
| Unadjusted period prevalence (%) | 0.25 | 0.25 | - |
| Median age at first event (years) | 38.00 | 38.00 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 782
- Matched controls
- 7820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
121
Kela drug reimbursment
Severe hypofunction of sexual glands
307.6
307.7
516
49
E28.3
ICD-10 Finland
Primary ovarian failure
2397.4
307.7
433
*
G03FB08
ATC
dydrogesterone and estrogen; systemic
10.9
200.8
263
346
N91.1
ICD-10 Finland
Secondary amenorrhoea
15.4
131.8
122
93
G03FB06
ATC
medroxyprogesterone and estrogen; systemic
10.0
122.7
156
191
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
6.3
105.7
633
3136
G03FB05
ATC
norethisterone and estrogen; systemic
5.4
84.3
202
473
25610
ICD-8 Finland
Ovarian dysfunction, Hypofunction
+∞
66.6
63
*
N97.8
ICD-10 Finland
Female infertility of other origin
7.6
60.2
91
134
G03DB01
ATC
dydrogesterone; oral
3.6
57.6
269
1006
G03FA01
ATC
norethisterone and estrogen; systemic
3.7
50.6
200
665
E28.8
ICD-10 Finland
Other ovarian dysfunction
451.7
43.6
43
*
H02AB09
ATC
hydrocortisone; systemic
11.0
42.3
46
44
G03FA12
ATC
medroxyprogesterone and estrogen; systemic
4.5
32.9
85
205
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
32.5
286
1443
E28.9
ICD-10 Finland
Ovarian dysfunction, unspecified
+∞
31.5
30
*
G03DA02
ATC
medroxyprogesterone; systemic
3.6
31.1
115
359
G03GA02
ATC
human menopausal gonadotrophin; parenteral
4.3
29.0
79
198
H01AC01
ATC
somatropin; parenteral
+∞
27.2
26
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.0
27.1
82
222
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
26.2
25
*
N97.0
ICD-10 Finland
Female infertility associated with anovulation
5.4
25.8
52
101
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.2
25.4
427
2766
G03FB09
ATC
levonorgestrel and estrogen; systemic
7.7
24.8
35
47
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
22.4
129
518
L04AA01
ATC
[U] ciclosporin
9.3
22.2
27
30
N91.0
ICD-10 Finland
Primary amenorrhoea
51.5
21.2
25
5
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.3
20.5
186
925
N80.1
ICD-10 Finland
Endometriosis of ovary
3.5
19.5
69
208
G03FA14
ATC
dydrogesterone and estrogen; systemic
2.9
19.4
98
366
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
6.7
19.3
31
48
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
18.8
18
*
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
14.1
17.9
30
22
H03AA01
ATC
levothyroxine sodium; systemic
2.0
17.5
242
1408
H02AA02
ATC
fludrocortisone; oral
51.2
17.1
20
*
LAF10
NOMESCO Finland
Bilateral salpingo-oophorectomy
4.8
17.0
39
85
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
14.5
16.9
28
20
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
16.7
16
*
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
+∞
16.7
16
*
E89.4
ICD-10 Finland
Postprocedural ovarian failure
48.6
16.1
19
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
16.1
308
1994
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
5.0
15.3
33
68
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
3.2
15.2
63
209
N80.4
ICD-10 Finland
Endometriosis of rectovaginal septum and vagina
4.4
14.9
38
90
LCD00
NOMESCO Finland
Hysterectomy
3.3
14.6
58
188
G03GA01
ATC
chorionic gonadotrophin; parenteral
2.7
14.1
78
305
LAF00
NOMESCO Finland
Unilateral salpingo-oophorectomy
5.6
13.6
26
48
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
13.4
210
1261
Z31.6
ICD-10 Finland
General counselling and advice on procreation
5.7
13.0
24
43
G03DA04
ATC
progesterone; systemic, rectal, vaginal
2.9
13.0
62
224
Q96.0
ICD-10 Finland
Karyotype 45,X
132.0
12.5
13
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.3
11.7
97
457
G03DC05
ATC
[U] tibolone
4.6
11.7
28
63
Z31.5
ICD-10 Finland
Genetic counselling
2.4
11.7
86
385
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.5
11.5
175
2722
N95.1
ICD-10 Finland
Menopausal and female climacteric states
1.8
11.4
193
1178
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
2.9
11.4
56
205
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
11.4
92
429
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.5
11.3
72
302
E, ,
ICD-9 Finland
25.4
11.2
15
6
C03CA01
ATC
furosemide; systemic
2.1
11.0
113
581
JAH01
NOMESCO Finland
Laparoscopy
2.6
11.0
63
251
B01AB05
ATC
enoxaparin; parenteral
1.8
10.9
221
1422
N91.2
ICD-10 Finland
Amenorrhoea, unspecified
8.4
10.9
23
28
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.9
10.5
161
950
N02AX02
ATC
tramadol; systemic, rectal
1.7
10.4
296
2086
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
+∞
10.4
10
*
127
Kela drug reimbursment
Transplant complication
8.4
10.4
22
27
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
33.0
10.4
13
*
UJF32
NOMESCO Finland
Coloscopy
1.8
10.2
165
991
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.8
10.1
162
970
N97.9
ICD-10 Finland
Female infertility, unspecified
2.2
10.1
92
451
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.2
10.1
85
404
N95.0
ICD-10 Finland
Postmenopausal bleeding
2.2
10.0
84
398
E22.1
ICD-10 Finland
Hyperprolactinaemia
40.6
10.0
12
*
A02BC05
ATC
esomeprazole; systemic
1.6
10.0
316
2285
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
9.8
76
348
L03AA02
ATC
filgrastim; parenteral
3.9
9.7
28
73
-, ,
ICD-10 Finland
4.5
9.6
23
52
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
4.5
9.6
23
52
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.8
9.5
29
79
Q96.9
ICD-10 Finland
Turner syndrome, unspecified
101.2
9.4
10
*
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
3.4
9.4
34
104
H01CC01
ATC
ganirelix; parenteral
2.7
9.3
50
193
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
0.5
9.2
70
1385
Z31.2
ICD-10 Finland
In vitrofertilization
5.1
9.1
19
38
J01MA12
ATC
levofloxacin; systemic
2.0
9.1
112
614
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.2
9.1
21
30
8113
FHL
Fractional scraping
3.0
9.0
39
133
A02BC02
ATC
pantoprazole; systemic
1.6
9.0
506
4160
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
9.0
79
381
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.9
8.9
128
738
1413
FHL
Laparoscopy and other therapeutic procedure
3.4
8.8
31
93
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
8.8
186
1204
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.2
8.8
23
56
A07AA02
ATC
nystatin; oral
2.7
8.8
47
181
G03GA06
ATC
follitropin beta; parenteral
2.7
8.7
47
182
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
3.7
8.6
27
75
H02AB06
ATC
prednisolone; systemic
1.6
8.6
352
2679
H01CA02
ATC
nafarelin; nasal
2.5
8.6
53
219
X11
ICPC
Menopausal symptom/complaint
3.3
8.6
32
100
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
10.2
8.6
16
16
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
0.5
8.5
86
1545
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
8.4
84
426
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
6.8
8.4
20
30
G02BA03
ATC
plastic IUD with progestogen
0.5
8.4
61
1232
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
8.4
307
2274
L02AE03
ATC
goserelin; implant
4.7
8.4
19
41
301
Kela drug reimbursment
Growth hormone
+∞
8.3
8
*
106
Kela drug reimbursment
Hypoparathyroidism
+∞
8.3
8
*
N70.1
ICD-10 Finland
Chronic salpingitis and oophoritis
4.2
8.3
22
54
6202X
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Other and unspecified ovarian cyst
4.6
8.2
19
42
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.6
8.1
46
182
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.1
8.1
22
55
A12AA04
ATC
calcium carbonate; oral
11.9
8.1
14
12
62400
ICD-8 Finland
Malposition of uterus, Retroversion and retroflexion
33.7
8.1
10
*
R4110
NOMESCO Finland
Physiotherapy
1.7
8.1
197
1320
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.6
8.1
48
195
N80.81
ICD-10 Finland
Endometriosis in sacrouteral ligament
10.2
8.1
15
15
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
2.2
8.0
69
331
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.8
8.0
133
802
XLA10, ,
NOMESCO Finland
2.3
7.8
59
267
JAH00
NOMESCO Finland
Laparotomy
3.9
7.7
22
57
L04AD01
ATC
ciclosporin; systemic
3.9
7.7
22
57
UKC02
NOMESCO Finland
Cystoscopy
2.2
7.7
67
323
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.0
7.7
21
53
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
7.6
118
695
A11CC02
ATC
dihydrotachysterol; oral
25.3
7.6
10
*
6171A
ICD-9 Finland
Endometriosis of ovary
6.3
7.6
19
31
G03DC03
ATC
lynestrenol; oral
2.9
7.5
35
125
TLW12
NOMESCO Finland
Insertion of frozen embryo
3.1
7.5
30
98
G03DC02
ATC
norethisterone; oral
1.9
7.5
99
555
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.0
7.5
21
54
XW000
NOMESCO Finland
Bone marrow biopsy
3.6
7.5
24
68
W12
ICPC
Contraception intrauterine
0.5
7.5
54
1096
102
Kela drug reimbursment
Diabetes insipidus
80.8
7.4
8
*
WW500
NOMESCO Finland
Blood transfusion
3.1
7.4
31
104
L02AE02
ATC
leuprorelin; implant, parenteral
3.1
7.4
30
99
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.9
7.4
34
121
X05
ICPC
Menstruation absent/scanty
3.6
7.3
24
69
62650
ICD-8 Finland
Disorders of menstruation, Irregular
11.0
7.3
13
12
E27.2
ICD-10 Finland
Addisonian crisis
+∞
7.3
7
*
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
+∞
7.3
7
*
E30.09
ICD-10 Finland
Delayed puberty NOS
+∞
7.3
7
*
Z3226
NOMESCO Finland
Physiotherapist
1.7
7.2
133
826
L04AA06
ATC
mycophenolic acid; systemic
4.1
7.1
19
47
Z3231
NOMESCO Finland
Registered nurse
1.6
7.0
190
1301
J01MA02
ATC
ciprofloxacin; systemic
1.5
7.0
244
1772
P01BA02
ATC
hydroxychloroquine; oral
2.0
7.0
76
399
JN4BD
NOMESCO Finland
Extensive body CT
2.3
6.9
53
242
D39.10
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary without histology
3.0
6.9
30
103
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.2
6.9
60
289
N91.5
ICD-10 Finland
Oligomenorrhoea, unspecified
8.4
6.8
14
17
N02AA05
ATC
oxycodone; systemic
1.9
6.8
84
461
ZXE90
NOMESCO Finland
More than 22 hours
40.4
6.8
8
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.6
6.7
38
151
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
2.7
6.7
34
128
G03GB02
ATC
clomifene; oral
2.8
6.6
32
117
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
6.6
57
274
KBV10
NOMESCO Finland
Removal of stent from ureter
6.9
6.5
15
22
A06AD11
ATC
lactulose; oral
2.0
6.5
67
344
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
3.7
6.5
20
55
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
6.5
53
249
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.8
6.4
31
113
H02AB07
ATC
prednisone; oral
1.8
6.4
93
536
ZXE80
NOMESCO Finland
More than 18 and less than 21 hours
70.4
6.4
7
*
E34.35
ICD-10 Finland
Abnormal growth retardation
70.4
6.4
7
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
70.4
6.4
7
*
Q96.8
ICD-10 Finland
Other variants of Turner syndrome
70.4
6.4
7
*
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
2.5
6.4
39
161
N80.8
ICD-10 Finland
Other endometriosis
11.1
6.3
11
10
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.2
6.3
50
232
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.2
6.3
50
232
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.3
6.3
48
219
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
6.3
180
1247
Z50.1
ICD-10 Finland
Other physical therapy
2.5
6.3
37
150
JAL96
NOMESCO Finland
Other excision of lesion of peritoneum
18.2
6.3
9
5
A12AA06
ATC
calcium lactate gluconate; oral
+∞
6.3
6
*
Q96
ICD-10 Finland
Turner syndrome
+∞
6.3
6
*
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
+∞
6.3
6
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
6.3
6
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.3
6.2
48
220
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
6.2
243
1802
G03FB01
ATC
norgestrel and estrogen; systemic
5.8
6.2
16
28
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
6.1
59
296
N99.4
ICD-10 Finland
Postprocedural pelvic peritoneal adhesions
5.6
6.0
16
29
LAC01
NOMESCO Finland
Laparoscopic excision of ovarian cyst
3.0
6.0
25
84
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
165
259
7.81
104.85
1.7
1.2
29.15
12.78
u/l
6.00
129
205
157
248
7.67
98.94
1.9
1.3
0.24
0.51
nmol/l
3.18
124
208
141
254
6.55
77.64
1.5
1.5
1.06
2.87
ug/l
3.26
64
234
70
5
153.50
67.11
1.0
1.0
—
—
—
0
0
204
867
2.83
32.75
2.2
1.3
46.20
26.32
iu/l
8.81
170
747
130
493
2.96
25.26
1.5
1.3
248.27
290.05
mu/l
1.60
124
439
39
58
7.02
25.26
1.3
1.3
—
—
—
0
0
177
839
2.43
21.85
1.4
1.2
135.55
148.17
u/ml
0.12
55
350
136
595
2.56
19.80
5.9
4.8
1.08
1.06
mmol/l
0.38
131
545
69
206
3.58
19.75
2.1
1.3
42.22
24.54
u/l
4.01
69
174
43
90
5.00
19.62
1.9
4.8
454.57
82.82
u/ml
—
9
31
51
127
4.23
18.81
1.1
1.2
3.00
4258.28
iu/ml
—
5
30
32
57
5.81
17.39
2.1
1.4
86.17
23.03
ng/l
1.02
32
57
146
700
2.33
17.25
2.7
1.8
353.57
378.01
nmol/l
0.68
138
655
365
2485
1.88
16.35
8.6
4.8
1.21
1.22
mmol/l
0.64
349
2320
401
2850
1.84
15.33
9.7
5.2
1.21
1.22
mmol/l
0.65
359
2476
512
4031
1.78
12.87
11.4
8.7
3.87
3.94
e9/l
0.33
459
3535
606
5062
1.88
12.02
10.1
6.9
74.81
73.94
u/l
0.25
579
4814
356
2568
1.71
11.91
6.1
4.2
36.38
37.12
g/l
1.81
336
2427
154
865
1.97
11.79
4.2
3.2
0.80
0.82
mmol/l
1.29
149
829
113
577
2.12
11.20
8.5
6.3
104.88
104.85
mmol/l
0.02
113
577
149
847
1.94
10.96
1.9
1.8
—
—
—
0
0
428
3288
1.67
10.95
3.1
2.4
76.40
75.31
nmol/l
0.35
404
3089
307
2181
1.67
10.51
4.2
3.1
2.35
2.35
mmol/l
0.24
281
2035
81
372
2.31
10.39
3.5
3.0
118.27
65.74
ng/l
0.67
73
334
29
77
3.87
9.85
2.9
1.8
4.62
5.03
mmol/24h
0.34
29
69
21
43
4.99
9.83
2.8
2.2
—
—
—
0
0
22
47
4.79
9.82
1.8
1.2
4.51
5.96
umol/l
1.23
22
42
80
375
2.26
9.78
1.7
1.7
—
—
—
0
0
424
3311
1.61
9.67
7.7
5.5
8.97
9.72
umol/l
1.58
402
3152
110
588
2.01
9.60
1.7
1.6
—
—
—
0
0
109
583
2.01
9.49
3.8
3.6
4.54
4.62
pmol/l
0.32
96
527
683
6079
1.98
9.24
6.7
4.8
14.66
14.25
pmol/l
4.65
666
5767
271
1936
1.61
8.70
3.5
2.8
26.38
64.38
e6/l
1.31
191
1421
445
3568
1.57
8.68
5.6
4.0
6.28
6.24
mmol/l
0.20
418
3252
239
1663
1.63
8.51
3.3
2.6
0.23
0.34
e6/l
0.61
154
1168
104
573
1.94
8.29
1.8
1.7
—
—
—
0
0
158
997
1.73
8.11
2.5
2.3
1.22
0.96
e6/l
0.42
75
487
158
1007
1.71
7.81
3.3
2.8
29.33
164.72
ng/l
3.01
103
532
83
433
2.03
7.72
3.3
3.2
1.81
1.87
mmol/l
0.06
73
366
734
6800
2.29
7.49
18.2
11.1
3.90
3.90
mmol/l
0.07
721
6648
324
2477
1.53
7.45
3.8
2.9
27.15
27.61
u/l
0.12
314
2361
37
138
2.76
7.35
1.5
1.2
—
—
—
0
0
731
6781
2.20
7.09
18.2
11.0
139.72
139.66
mmol/l
0.32
718
6646
270
2010
1.52
6.91
2.5
2.4
78.71
58.82
u/l
0.41
251
1881
541
4649
1.53
6.85
4.9
4.1
93.63
1041.78
e6/l
—
8
54
590
5168
1.58
6.85
5.9
4.1
11.05
9.59
mm/h
2.52
568
4903
141
904
1.68
6.76
2.9
2.4
3.27
4.51
e6/l
0.84
57
395
124
773
1.72
6.58
2.6
2.3
22.39
24.12
%
0.71
116
714
165
1110
1.62
6.54
2.6
2.9
627.88
540.90
ng/l
0.16
144
909
52
242
2.23
6.50
4.8
2.8
1.05
1.42
mmol/l
0.39
38
176
329
2588
1.47
6.28
2.3
1.9
92.50
99.26
pmol/l
1.99
184
1390
454
3808
1.46
6.14
4.0
3.4
0.00
0.00
estimate
0.50
85
771
30
111
2.77
6.08
2.9
2.4
—
—
—
0
0
460
3872
1.46
6.08
4.0
3.5
0.05
0.01
estimate
0.45
85
758
135
881
1.64
6.01
2.4
2.2
2.50
2.45
g/l
0.41
124
810
80
453
1.85
5.86
10.0
7.6
0.38
0.92
mmol/l
0.50
75
361
118
749
1.68
5.84
3.1
2.4
5.08
5.51
umol/l
0.28
99
634
161
1115
1.56
5.58
3.0
2.2
2.43
2.42
mmol/l
0.38
141
1004
104
646
1.70
5.57
2.3
2.3
59.20
37.55
u/l
0.54
88
533
204
1491
1.50
5.50
3.0
2.3
305.55
297.35
umol/l
0.64
188
1349
724
6786
1.90
5.36
7.8
5.7
1.70
1.73
mu/l
0.40
707
6513
453
3851
1.42
5.36
4.1
3.4
0.00
3.75
estimate
0.80
85
777
705
6556
1.77
5.36
15.3
9.9
90.96
91.16
ml/min/173m2
0.10
643
5956
240
1828
1.45
5.21
4.0
3.2
7.01
7.72
mmol/l
1.55
208
1592
17
49
3.52
5.19
3.3
2.9
529.17
449.87
e6/l
0.38
12
39
179
1292
1.50
5.09
3.1
2.4
8.05
9.05
e6/l
0.31
155
1174
141
971
1.55
4.98
2.5
2.2
13.48
14.73
umol/l
1.45
134
903
17
51
3.39
4.91
3.8
2.8
190.75
206.09
e6/l
0.11
12
43
214
1615
1.45
4.82
1.3
1.3
16.75
11.22
u/ml
0.47
83
672
24
90
2.72
4.78
3.6
1.9
10.46
6.31
pmol/l
1.20
24
90
224
1711
1.43
4.72
2.2
2.1
137.12
130.97
u/l
0.12
216
1640
211
1597
1.44
4.66
1.9
1.5
19.69
21.06
nmol/l
0.84
189
1416
26
104
2.55
4.59
1.6
1.2
—
—
—
0
0
26
104
2.55
4.59
1.6
1.2
—
—
—
0
0
41
202
2.09
4.51
1.4
1.3
—
—
—
0
0
251
1970
1.40
4.51
2.5
2.7
13.19
67.88
ng/l
0.70
126
947
10
15
6.74
4.47
3.0
2.1
61.81
91.53
ug/l
—
10
15
215
1644
1.42
4.47
2.4
2.0
—
—
—
0
0
49
259
1.95
4.46
1.4
1.6
—
—
—
0
0
13
28
4.70
4.38
1.8
1.3
67.18
70.46
nmol/24h
0.09
13
28
223
1747
1.39
3.97
1.4
1.3
23.08
24.28
iu/ml
0.07
75
526
266
2150
1.36
3.89
1.4
1.4
1.38
1.71
u/ml
0.20
71
630
200
1544
1.40
3.88
4.9
3.9
13.49
9.56
mg/mmol
0.26
112
918
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
23
95
2.46
3.83
3.2
5.7
0.27
0.39
iu/ml
1.14
14
54
16
55
2.95
3.75
1.8
1.3
21.71
23.33
umol/l
0.07
16
50
23
98
2.39
3.60
1.0
1.1
—
—
—
0
0
107
747
1.50
3.53
1.6
1.6
1163.65
1163.34
nmol/l
0.00
89
575
77
500
1.60
3.51
2.5
2.2
0.23
0.23
g/l
0.25
77
478
229
1837
1.35
3.45
1.9
1.4
2.05
2.14
g/l
0.37
130
1212
51
301
1.74
3.34
1.4
1.4
—
—
—
0
0
19
77
2.50
3.31
1.5
1.2
—
60.33
—
0
6
72
470
1.59
3.22
3.6
4.3
6.75
19.10
ug/l
0.58
50
348
31
158
2.00
3.18
3.5
2.7
0.50
1.95
index
1.37
12
75
69
448
1.59
3.16
1.6
1.4
—
—
—
0
0
248
2036
1.32
3.15
4.3
3.5
0.01
0.00
estimate
0.29
85
754
86
588
1.52
3.14
5.2
4.6
—
—
—
0
0
48
286
1.72
3.06
3.2
1.8
1.19
1.19
g/l
0.05
48
270
155
1192
1.37
3.03
2.4
2.5
144.80
94.53
ug/g
0.99
128
944
5
5
10.05
2.98
2.4
1.2
—
—
—
0
0
215
1743
1.32
2.96
2.4
2.1
2.65
2.52
mg/l
0.40
193
1532
83
572
1.50
2.93
2.6
2.4
10.52
21.39
au/ml
1.86
11
70
683
6470
1.44
2.91
4.8
4.0
5.56
5.61
mmol/l
0.56
659
6128
7
13
5.42
2.87
2.9
2.8
0.94
1.87
ratio
—
7
13
103
745
1.44
2.86
2.0
2.1
1880.48
7499.29
u/l
3.36
45
324
48
292
1.69
2.85
1.6
1.4
68.29
135.70
pmol/l
0.90
48
284
76
522
1.51
2.74
1.3
1.3
65.25
36.14
au/ml
—
6
30
19
85
2.27
2.72
1.5
1.3
—
—
—
0
0
42
251
1.71
2.67
1.5
1.5
0.30
0.31
iu/ml
—
9
35
40
236
1.73
2.66
2.5
2.1
96.57
96.96
%
0.04
40
227
58
379
1.57
2.62
3.1
2.0
12.32
6.14
iu/ml
0.53
24
85
55
355
1.59
2.62
1.7
1.8
—
—
—
0
0
751
7286
1.78
2.58
20.6
13.0
67.23
65.86
umol/l
1.10
744
7215
37
216
1.75
2.56
2.4
2.0
—
—
—
0
0
329
2860
1.26
2.56
2.2
1.8
1.48
1.33
mmol/l
2.26
303
2535
12
44
2.75
2.55
2.0
1.3
—
—
—
0
0
13
50
2.63
2.54
2.8
1.4
25.00
17.17
mg/l
—
5
25
73
509
1.48
2.46
4.7
2.2
67.77
79.91
ml/min/173m2
1.42
33
199
16
70
2.31
2.42
1.3
1.4
—
—
—
0
0
11
38
2.92
2.42
3.7
1.4
2.00
2.08
umol/l
0.16
11
32
19
90
2.14
2.40
1.3
1.5
—
—
—
0
0
725
6989
1.51
2.38
18.1
11.5
19.38
19.04
mg/l
0.11
624
5570
10
33
3.06
2.36
1.2
1.3
—
—
—
0
0
7
18
3.91
2.25
3.1
3.1
1.57
1.78
%
—
7
18
28
157
1.81
2.24
2.1
1.6
—
—
—
0
0
33
197
1.70
2.15
1.9
1.9
—
—
—
0
0
38
590
0.63
2.13
1.4
1.5
55.05
59.98
ug/l
0.36
27
492
202
1693
1.26
2.09
2.0
1.8
0.83
0.82
mg/l
0.03
150
1293
29
170
1.73
2.03
1.2
1.4
269.94
231.82
u/ml
0.25
17
117
378
3398
1.22
2.01
3.0
2.6
—
—
estimate
—
0
0
10
38
2.65
2.01
1.0
1.0
—
—
—
0
0
76
1016
0.72
1.99
1.5
1.6
1080.09
1011.23
mu/l
0.25
60
841
46
306
1.53
1.97
1.4
1.3
33.29
17.61
u/ml
—
7
15
9
34
2.67
1.87
4.7
1.4
26.78
29.38
umol/l
—
9
29
43
286
1.53
1.86
1.4
1.3
3.47
2.16
u/ml
—
7
27
748
7297
1.58
1.86
14.3
9.9
25.16
23.60
u/l
1.30
741
7142
43
287
1.53
1.83
1.4
1.3
2.14
15.17
u/ml
—
8
52
25
145
1.75
1.83
2.2
1.6
—
—
—
0
0
8
29
2.78
1.79
1.0
1.3
—
—
—
0
0
552
5183
1.22
1.78
3.3
3.0
36.86
33.81
u/l
0.52
534
5007
7
24
2.93
1.72
1.9
1.5
9.40
7.79
ug/l
—
7
24
86
661
1.34
1.72
4.0
3.7
34.68
32.48
%
1.01
74
482
15
280
0.53
1.71
1.1
1.3
—
—
—
0
0
6
19
3.17
1.66
1.2
1.1
—
—
—
0
0
29
181
1.63
1.65
1.3
1.3
—
61.73
—
0
6
459
4259
1.19
1.59
3.5
3.2
74.27
65.63
ug/l
0.88
439
4078
328
2959
1.19
1.57
3.8
3.2
0.04
0.03
estimate
0.08
69
643
57
418
1.39
1.54
7.5
2.7
1.22
1.23
mmol/l
0.74
52
351
5
15
3.35
1.52
1.4
1.1
8.80
14.40
u/l
—
5
15
14
72
1.96
1.49
1.6
1.5
—
—
—
0
0
51
691
0.72
1.48
1.4
1.4
—
—
—
0
0
14
73
1.93
1.44
1.6
1.5
—
—
—
0
0
14
73
1.93
1.44
1.6
1.5
—
—
—
0
0
5
16
3.14
1.44
1.0
1.1
—
—
—
0
0
664
6400
1.25
1.43
4.2
3.6
1.29
1.19
mmol/l
2.70
641
6096
15
81
1.87
1.41
5.2
4.0
0.96
1.57
ratio
—
8
45
7
29
2.43
1.39
1.0
1.2
—
—
—
0
0
93
1144
0.79
1.37
1.6
1.8
3.17
3.25
ratio
0.28
64
849
17
97
1.77
1.35
1.1
1.1
—
0.42
—
0
6
193
1681
1.20
1.35
4.1
3.4
1.02
2.85
kg/l
0.80
121
1103
70
891
0.76
1.35
1.3
1.7
3.55
3.42
mmol/l
0.30
41
601
42
300
1.42
1.34
2.4
2.3
1.02
1.02
ratio
0.31
30
276
39
275
1.44
1.33
1.8
1.5
—
—
—
0
0
9
43
2.11
1.30
3.0
1.7
—
—
—
0
0
9
43
2.11
1.30
3.0
1.7
—
—
—
0
0
9
43
2.11
1.30
3.0
1.7
—
—
—
0
0
13
69
1.90
1.29
1.7
1.5
—
—
—
0
0
13
69
1.90
1.29
1.2
1.2
—
—
—
0
0
13
69
1.90
1.29
1.7
1.5
—
—
—
0
0
13
69
1.90
1.29
1.7
1.5
—
—
—
0
0
5
18
2.79
1.28
1.6
1.4
—
—
—
0
0
8
35
2.30
1.27
1.6
1.5
—
—
—
0
0
29
420
0.68
1.25
1.3
1.7
3.36
3.25
mg/l
0.05
23
294
8
36
2.23
1.24
3.1
1.4
1.74
2.14
nmol/l
—
8
28
13
70
1.87
1.24
1.2
1.2
—
—
—
0
0
9
45
2.01
1.23
1.0
1.1
919.59
1651.18
miu/ml
—
9
45
40
544
0.72
1.22
1.5
1.4
—
—
—
0
0
40
289
1.40
1.22
1.9
2.2
4.70
4.03
iu/l
0.18
15
130
23
148
1.57
1.21
3.6
2.0
460.68
163.47
ug/l
0.58
18
134
6
26
2.32
1.19
2.8
1.6
15.66
34.81
ug/l
—
6
26
15
87
1.74
1.15
1.1
1.3
—
—
—
0
0
599
5751
1.18
1.15
3.9
3.8
—
—
—
0
0
20
126
1.60
1.15
1.8
1.4
—
—
—
0
0
5
20
2.51
1.15
1.6
1.4
—
—
—
0
0
137
1178
1.20
1.11
1.8
1.6
407.83
53588945.55
pmol/l
2.30
121
1045
30
421
0.70
1.11
1.7
1.8
—
—
—
0
0
61
480
1.29
1.09
1.3
1.3
235.18
231.85
miu/ml
0.03
22
250
8
41
1.96
1.09
1.9
2.2
—
—
—
0
0
29
202
1.45
1.09
1.2
1.2
—
—
—
0
0
33
236
1.42
1.08
1.5
1.5
—
—
—
0
0
15
89
1.70
1.08
2.5
1.7
—
—
—
0
0
10
52
1.94
1.06
2.8
1.8
—
—
—
0
0
37
495
0.73
1.04
1.5
1.6
—
—
—
0
0
17
106
1.62
1.03
1.8
1.4
—
—
—
0
0
13
75
1.75
1.03
1.3
1.4
—
—
—
0
0
11
60
1.85
1.03
2.6
1.7
—
—
—
0
0
11
60
1.85
1.03
1.0
1.1
135.27
107.83
pmol/l
0.82
11
60
18
116
1.56
0.97
1.7
1.4
—
—
—
0
0
10
54
1.86
0.97
1.3
1.1
—
—
—
0
0
10
54
1.86
0.97
1.3
1.2
—
—
—
0
0
62
499
1.26
0.96
1.4
1.5
—
—
—
0
0
79
654
1.23
0.95
1.4
1.3
83.61
181.35
u/ml
1.16
73
611
33
243
1.37
0.94
1.0
1.1
3.96
7.73
eliau/ml
—
5
40
8
144
0.55
0.94
1.4
1.9
—
—
—
0
0
25
349
0.71
0.93
1.6
2.0
—
—
—
0
0
43
551
0.77
0.92
1.4
1.5
1.19
1.20
ratio
0.01
24
342
43
551
0.77
0.92
1.4
1.5
1.21
0.95
ratio
0.52
24
341
43
550
0.77
0.91
1.4
1.5
1.08
1.15
ratio
0.25
24
340
16
102
1.58
0.91
2.3
1.3
—
—
—
0
0
239
2185
1.14
0.88
1.7
1.7
—
—
—
0
0
12
72
1.68
0.85
3.7
1.5
8.72
7.78
u/ml
0.09
12
72
643
6253
1.16
0.85
5.9
4.7
37.45
37.23
mmol/mol
0.30
614
5972
28
205
1.38
0.84
1.2
1.2
—
—
—
0
0
6
33
1.82
0.79
1.0
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.6
—
88.26
—
0
26
62
514
1.22
0.77
1.6
1.5
—
—
—
0
0
64
534
1.22
0.75
1.1
1.1
—
—
—
0
0
7
39
1.80
0.72
2.3
3.1
4149.43
549.67
u/ml
—
7
39
13
84
1.56
0.72
1.5
1.9
—
—
—
0
0
7
40
1.76
0.71
1.0
1.1
98.86
84.00
%
—
7
31
7
40
1.76
0.71
1.0
1.1
—
—
—
0
0
5
26
1.93
0.70
1.0
1.0
—
—
—
0
0
27
352
0.76
0.69
2.3
1.5
0.26
0.28
mg/l
—
10
144
12
77
1.57
0.69
1.9
1.4
—
—
—
0
0
7
43
1.63
0.67
1.7
1.7
—
70.50
%
—
0
6
29
371
0.77
0.65
1.4
1.5
63.95
56.20
ug/l
0.31
29
371
145
1599
0.89
0.65
2.1
2.1
—
—
—
0
0
7
44
1.60
0.65
4.1
2.3
1498.29
1179.43
mg
—
7
44
12
79
1.53
0.63
2.8
2.4
8.71
207.29
ug/min
—
7
52
11
71
1.56
0.62
1.2
1.1
—
—
—
0
0
19
139
1.38
0.61
1.2
1.1
—
—
—
0
0
26
201
1.30
0.59
1.5
1.4
319.75
329.64
ug/g
0.07
16
106
60
512
1.19
0.59
3.3
2.6
—
—
—
0
0
10
64
1.57
0.58
1.0
1.1
1.07
1.04
ratio
—
10
51
700
6889
1.15
0.58
5.4
4.6
2.87
2.88
mmol/l
0.11
672
6601
14
98
1.44
0.56
1.1
1.1
—
—
—
0
0
13
90
1.45
0.55
1.0
1.3
3.08
0.29
u/ml
—
7
43
23
177
1.31
0.55
1.3
1.6
1.39
14.09
e6/l
1.58
18
132
91
1021
0.88
0.55
1.7
1.8
—
—
—
0
0
6
38
1.58
0.54
1.8
1.2
126.00
110.07
%
—
6
30
13
181
0.71
0.53
1.1
1.0
0.04
0.08
u/ml
—
5
48
34
411
0.82
0.50
1.1
1.1
1.62
1.61
g/l
0.12
34
411
10
67
1.50
0.50
1.1
1.1
1.14
1.04
u/l
—
5
29
215
2287
0.92
0.49
1.6
1.6
—
—
—
0
0
13
174
0.74
0.43
1.0
1.1
4.56
13.73
au/ml
—
5
58
18
140
1.29
0.42
1.1
1.1
—
—
—
0
0
8
57
1.41
0.42
1.1
1.3
—
—
—
0
0
14
105
1.34
0.41
1.1
1.1
—
—
—
0
0
10
71
1.41
0.39
1.6
1.4
—
—
—
0
0
14
106
1.33
0.39
1.3
1.2
—
—
—
0
0
5
37
1.35
0.37
1.6
1.4
—
—
—
0
0
30
254
1.19
0.36
1.2
1.2
6.80
55.68
u/ml
—
6
26
115
1237
0.92
0.35
2.0
2.0
—
—
—
0
0
19
233
0.81
0.35
1.8
2.3
5.15
4.75
umol/l
0.10
14
166
36
415
0.86
0.35
1.2
1.1
0.93
0.86
g/l
0.82
36
415
6
45
1.34
0.34
2.0
1.2
0.35
0.29
g/l
—
6
39
38
331
1.16
0.33
1.8
1.6
27.19
9.86
u/ml
—
7
87
7
52
1.35
0.31
2.4
1.4
84.00
67.90
umol/l
—
7
52
692
6848
1.09
0.31
5.2
4.2
4.92
4.85
mmol/l
0.97
673
6592
34
296
1.16
0.31
1.3
1.3
—
—
—
0
0
17
138
1.24
0.30
1.8
1.7
6450.58
9662.41
e6/l
0.28
12
102
12
93
1.29
0.30
1.3
1.1
—
—
—
0
0
20
167
1.20
0.28
1.1
1.2
—
—
—
0
0
18
150
1.20
0.26
1.2
1.2
9.00
3.85
u/ml
—
7
55
11
86
1.28
0.26
1.6
1.8
—
—
—
0
0
234
2258
1.05
0.25
3.4
2.7
0.04
0.02
estimate
0.26
69
652
9
76
1.19
0.24
1.1
1.1
—
—
—
0
0
11
136
0.81
0.23
2.2
1.6
—
—
—
0
0
11
88
1.25
0.22
1.2
1.1
—
—
—
0
0
5
40
1.25
0.22
1.0
1.1
328.20
133.16
iu/ml
—
5
40
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
17
145
1.18
0.20
1.2
1.2
5.00
3.59
u/ml
—
7
61
170
1764
0.95
0.20
2.2
2.2
—
—
—
0
0
688
6829
1.06
0.19
5.0
4.1
1.61
1.56
mmol/l
2.52
668
6535
11
90
1.23
0.19
1.4
1.1
—
—
—
0
0
14
164
0.85
0.18
1.3
1.3
—
—
—
0
0
12
100
1.20
0.18
1.1
1.1
—
—
—
0
0
15
129
1.17
0.17
3.3
3.4
17.67
22.26
mg/l
—
9
87
30
273
1.10
0.16
1.1
1.1
0.53
2.24
u/ml
2.32
15
135
11
92
1.20
0.16
1.2
1.1
—
—
—
0
0
11
92
1.20
0.16
1.4
1.1
—
—
—
0
0
11
92
1.20
0.16
1.4
1.1
—
—
—
0
0
10
83
1.21
0.15
1.2
1.8
—
—
—
0
0
8
99
0.81
0.13
1.0
1.2
—
1434.64
—
0
11
11
128
0.86
0.13
1.5
1.5
—
—
—
0
0
5
45
1.11
0.10
1.6
1.5
0.52
0.46
e9/l
—
5
45
5
62
0.81
0.08
1.0
1.0
—
—
—
0
0
18
190
0.95
0.04
1.1
1.4
3.88
3.68
mmol/l
0.24
18
177
767
7661
1.06
0.03
26.9
17.9
269.37
269.07
e9/l
0.05
756
7570
53
541
0.98
0.03
1.8
1.5
—
—
—
0
0
16
152
1.05
0.02
1.0
1.1
1.92
2.66
eliau/ml
—
6
76
15
143
1.05
0.01
1.3
1.4
—
—
—
0
0
767
7664
1.04
0.00
26.8
17.9
4.39
4.46
e12/l
4.85
756
7558
23
233
0.99
0.00
1.0
1.1
0.16
1.75
u/ml
4.08
15
105
25
247
1.01
0.00
1.0
1.1
0.54
3.78
u/ml
3.23
14
131
98
978
1.00
0.00
1.5
1.6
1.49
1.33
%
2.19
90
880
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
1.1
1.2
6.85
17.17
u/l
—
7
57
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
8
79
1.01
-0.00
5.7
3.8
18.19
67.40
u/ml
—
8
79
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.8
—
10.78
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.8
—
1.00
—
0
15
5
51
0.98
-0.00
1.8
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
1.48
—
0
9
0
7
0.00
-0.00
0.0
5.4
—
30.00
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
0.01
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
26.50
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_OVARFAIL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_OVARFAIL | 2.676 [2.14, 3.35] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.077 |
During the follow-up period (1.1.1998 — 31.12.2019), 93 out of 2006 females with E4_OVARFAIL died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have E4_OVARFAIL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.258% | No data |
| 5 | 1.402% | No data |
| 10 | 3.668% | No data |
| 15 | 7.081% | No data |
| 20 | 11.799% | No data |
Relationships between endpoints
↥Index endpoint: E4_OVARFAIL – Primary ovarian failure
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data