No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
942 |
4. Check minimum number of eventsNone |
942 |
5. Include endpointsNone |
942 |
6. Filter based on genotype QC (FinnGen only) |
942 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Overjet
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 40513 | 20206 | 20288 |
| Only index persons | 33183 | 16591 | 16592 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.57 | 0.58 | 0.57 |
| Only index persons | 0.62 | 0.61 | 0.63 |
| Median age at first event (years) | |||
| Whole population | 10.74 | 10.78 | 10.68 |
| Only index persons | 11.41 | 11.51 | 11.31 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 942 | 637 | 305 |
| Unadjusted period prevalence (%) | 0.19 | 0.22 | 0.13 |
| Median age at first event (years) | 17.64 | 19.64 | 13.48 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 812
- Matched controls
- 8081
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
+∞
323.0
812
*
K07.13
ICD-10 Finland
Retrognaty, mandibular
34.1
225.4
301
137
K07.23
ICD-10 Finland
Deep bite
14.1
208.8
413
551
SBB10
NOMESCO Finland
Teeth copy
8.4
166.8
522
1424
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
19.8
162.9
259
187
EB1MA
NOMESCO Finland
Cephalometry with X-ray
8.2
130.6
350
686
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
8.1
112.5
293
529
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
6.8
106.1
323
720
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
6.7
102.8
315
703
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
6.1
95.4
313
750
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
68.7
94.4
108
18
SXC05
NOMESCO Finland
Other oral or dental procedure
5.0
83.8
346
1050
SJC50
NOMESCO Finland
Removal of orthodontisk device with at least 7 brackets
6.1
82.3
259
572
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
6.5
80.4
237
479
SAA04
NOMESCO Finland
Special inverstigation of mouth
5.7
79.5
269
646
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
6.2
77.6
238
504
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
5.6
74.2
250
590
SJD30
NOMESCO Finland
Demanding attachment of arrow to fixed orthodontisk device
7.1
71.5
192
336
SJB60
NOMESCO Finland
External device grinding and adaptation
6.2
71.3
218
454
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
5.2
66.6
242
613
SAA03
NOMESCO Finland
Extended examination of mouth
4.1
66.5
639
3854
SJB10
NOMESCO Finland
Fitting of loose orthodontic device with user information, demanding
7.7
61.9
154
237
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
4.1
60.7
293
973
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
4.1
58.5
281
923
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.4
58.2
536
2952
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
4.6
57.3
231
640
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.3
56.3
472
2400
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
7.4
50.9
129
201
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
4.0
47.6
221
685
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
3.9
47.4
231
747
K07.24
ICD-10 Finland
Open bite
8.3
44.7
104
141
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
4.9
44.2
159
381
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
3.7
42.0
220
744
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
3.8
35.9
171
529
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
4.3
34.9
144
390
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
4.4
33.0
129
331
SJC40
NOMESCO Finland
Removal of orthodontisk device with at most 6 brackets
3.1
29.9
187
704
K07.60
ICD-10 Finland
Snapping jaw
4.9
28.2
98
222
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.4
28.1
152
512
SJX20
NOMESCO Finland
Check-up visit for orthodontisk therapy
3.3
27.8
156
538
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
6.8
26.9
70
111
SJB30
NOMESCO Finland
Extraoral device arrangement and user information
4.9
26.1
89
197
WZA90
NOMESCO Finland
Other doctors statement
2.3
25.5
323
1798
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
4.6
25.0
90
211
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
5.0
24.9
84
184
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
4.6
19.2
69
161
SJD50
NOMESCO Finland
Production and attachment of palatinal or lingual arrow
4.7
18.8
65
146
EBB15
NOMESCO Finland
Insertion of dental implant abutment
25.6
18.3
25
10
EBB10
NOMESCO Finland
Insertion of dental implant
14.7
18.2
30
21
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
16.3
17.1
27
17
OIKK
NOMESCO Finland
NA
2.4
16.4
161
764
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
10.3
16.0
31
31
SAA02
NOMESCO Finland
Basic examination of mouth
2.3
15.9
706
6032
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
32.2
14.8
19
6
K07.55
ICD-10 Finland
Malocclusion caused by tongue, lip and finger habits
13.6
14.2
24
18
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
2.2
14.2
158
795
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
13.9
235
1401
Z01.2
ICD-10 Finland
Dental examination
1.8
13.8
477
3604
EEC05
NOMESCO Finland
Le Fort I osteotomy
15.0
13.6
22
15
SDA02
NOMESCO Finland
Parodonthologic therapy
1.8
13.3
311
2071
SAA01
NOMESCO Finland
Simple examination of mouth
1.9
13.2
639
5346
EMAK
NOMESCO Finland
NA
4.9
13.2
43
92
SPC20
NOMESCO Finland
Attachment of crone of tooth to implant
22.9
12.9
18
8
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
12.6
407
2978
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
10.7
12.3
23
22
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.8
11.9
251
1602
K03.00
ICD-10 Finland
Approximal wear
3.3
11.6
59
188
SJX00
NOMESCO Finland
Reparation of orthodontiskt device by dentist
4.6
11.4
39
88
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.4
11.4
102
460
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
4.6
10.9
37
83
K07.33
ICD-10 Finland
Crowding of tooth or teeth
7.7
10.7
24
32
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
21.7
10.7
15
7
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.6
10.7
48
140
D82
ICPC
Teeth/gum disease
1.7
10.6
327
2325
OIKJA
NOMESCO Finland
NA
4.4
10.6
37
86
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
2.0
10.4
140
756
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
6.9
10.4
25
37
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
26.3
9.8
13
5
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
4.5
9.6
33
76
OIKAL
NOMESCO Finland
NA
2.6
9.5
71
292
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.8
9.2
182
1126
OIKH
NOMESCO Finland
NA
2.1
9.1
109
559
-1
NOMESCO Finland
NA
1.6
8.9
422
3304
XX1AW
NOMESCO Finland
Written report from X-ray examination without contrast peformed elsewhere
90.6
8.4
9
*
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
12.9
8.4
14
11
SPB10
NOMESCO Finland
Production of temporary crone to tooth
12.9
8.4
14
11
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
7.9
8.4
18
23
SPA20
NOMESCO Finland
Selection and insertion of implantdistans
33.6
8.1
10
*
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.1
8.0
91
456
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.5
8.0
512
4247
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
13.1
7.9
13
10
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
6.2
7.8
20
33
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
15.1
7.7
12
8
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.8
7.4
122
706
D19
ICPC
Teeth/gum symptom/complaint
1.6
7.3
249
1772
SDA12
NOMESCO Finland
Treatment of complicated periodontal disease
8.4
7.3
15
18
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
10.9
7.3
13
12
K07.61
ICD-10 Finland
Cracking jaw joint
3.4
7.3
33
99
EBA12
NOMESCO Finland
Complicated surgical removal of tooth
2.9
7.2
42
150
SXC03
NOMESCO Finland
Other oral or dental procedure
6.6
7.1
17
26
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
8.8
7.0
14
16
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
2.5
7.0
52
213
HAHOM
NOMESCO Finland
NA
4.0
6.7
25
64
K06.00
ICD-10 Finland
Local gingivore traction
5.2
6.6
19
37
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
4.1
6.6
24
60
K02.0
ICD-10 Finland
Caries limited to enamel
1.5
6.5
229
1635
EDC30
NOMESCO Finland
Genioplasty
70.1
6.4
7
*
SAALT
NOMESCO Finland
NA
2.6
6.3
42
164
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
18.1
6.3
9
5
K05.31
ICD-10 Finland
Periodontitis pronounced
2.7
6.2
40
153
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
12.6
6.1
10
8
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
99
516
2.02
9.00
5.1
4.5
—
—
—
0
0
18
36
5.05
8.58
7.4
8.3
—
—
—
0
0
94
512
1.92
7.53
3.8
3.1
34.11
32.67
%
0.59
61
375
213
1480
1.56
7.03
2.8
2.6
18.30
29.87
ng/l
0.84
107
647
19
49
3.92
6.68
15.5
8.8
—
—
—
0
0
55
269
2.10
5.98
1.4
1.3
—
—
—
0
0
17
44
3.90
5.96
7.8
6.5
—
—
—
0
0
17
44
3.90
5.96
7.8
6.2
—
—
—
0
0
101
623
1.69
5.37
1.8
1.6
1228.04
1145.66
nmol/l
0.37
71
485
130
856
1.59
5.34
1.5
1.5
471.60
8945696.65
pmol/l
0.50
102
749
365
2972
1.36
4.89
4.0
2.9
73.70
69.36
nmol/l
2.19
336
2769
129
868
1.55
4.83
2.6
2.4
352.28
371.13
nmol/l
0.51
117
823
22
80
2.78
4.59
1.2
1.1
—
—
—
0
0
35
160
2.22
4.55
3.4
4.0
3.45
3.78
e9/l
0.48
35
160
35
163
2.18
4.36
3.5
4.5
50.20
53.55
%
0.96
35
163
389
3250
1.33
4.23
4.7
3.1
0.00
0.00
estimate
0.00
81
602
388
3247
1.32
4.15
6.2
4.5
0.00
0.00
estimate
0.50
82
627
215
1651
1.38
4.04
5.6
3.4
0.00
0.00
estimate
0.80
80
609
390
3281
1.31
3.96
4.8
3.2
0.00
0.00
estimate
0.00
82
605
11
29
3.81
3.78
1.3
1.4
0.89
0.97
g/l
0.37
11
29
448
3859
1.30
3.76
3.7
3.1
69.67
65.53
ug/l
0.15
418
3649
294
2399
1.32
3.67
4.8
3.1
—
—
—
0
0
140
1014
1.44
3.66
4.2
2.6
13.68
14.42
umol/l
0.62
133
962
347
2903
1.30
3.59
4.1
4.0
—
—
—
0
0
563
5021
1.29
3.50
5.3
4.2
8.03
8.20
mm/h
0.15
513
4673
232
1848
1.33
3.39
3.1
2.9
2.38
2.38
mmol/l
0.09
196
1674
222
1777
1.32
3.12
4.8
3.7
8.40
8.76
mmol/l
0.43
203
1601
50
299
1.70
3.06
1.2
1.4
—
—
—
0
0
594
5381
1.27
3.03
8.0
7.9
99.40
98.96
ml/min/173m2
0.16
439
3886
785
7381
1.35
2.95
10.3
8.5
28.23
25.02
u/l
0.35
746
7161
178
1391
1.34
2.95
2.2
2.3
167.25
250.80
u/l
0.98
167
1332
61
395
1.57
2.76
2.1
1.8
—
—
—
0
0
122
912
1.38
2.68
4.4
2.7
2.61
2.53
g/l
0.60
115
858
14
54
2.60
2.68
1.6
1.7
31.14
32.83
pg
0.51
14
54
113
835
1.39
2.66
4.7
2.8
21.39
22.97
%
0.78
105
762
99
716
1.42
2.64
4.2
4.5
0.22
0.22
g/l
0.01
92
690
794
7513
1.33
2.58
12.3
10.2
19.42
21.38
mg/l
0.89
573
5252
80
559
1.46
2.56
2.0
2.1
6.27
6.93
u/l
0.27
59
407
642
5920
1.25
2.56
4.2
3.8
14.48
14.37
pmol/l
0.64
566
5413
28
149
1.90
2.54
1.5
1.5
20.57
17.43
u/l
0.19
21
129
511
4606
1.23
2.50
6.8
6.0
93.19
94.31
u/l
0.15
478
4326
138
1065
1.34
2.49
1.3
1.2
11.24
26.20
iu/ml
5.02
33
306
25
129
1.95
2.49
2.0
1.6
—
—
—
0
0
47
294
1.62
2.48
2.9
1.9
—
11.07
—
0
5
478
4291
1.22
2.39
4.6
3.6
37.80
32.48
u/l
0.27
435
4105
10
34
2.95
2.39
3.0
2.6
24.02
16.52
umol/l
—
10
34
188
1526
1.28
2.35
2.9
2.7
—
—
—
0
0
10
35
2.86
2.29
1.9
1.7
50.60
9.77
mg/l
—
5
12
8
23
3.48
2.26
3.9
2.5
—
—
—
0
0
176
1426
1.28
2.23
5.4
3.0
7.06
7.88
e6/l
0.26
158
1252
10
36
2.78
2.18
1.3
1.2
—
92.17
—
0
6
11
42
2.62
2.17
1.7
1.7
45.50
45.07
%
—
6
30
24
129
1.87
2.15
4.2
3.3
20.23
25.51
mg/l
0.31
14
83
114
876
1.34
2.13
3.2
4.3
704.79
635.84
ng/l
0.08
92
726
68
480
1.44
2.11
5.4
3.8
1.59
1.62
ug/l
0.05
56
433
45
292
1.56
2.08
3.0
2.0
82.33
107.18
u/ml
—
6
31
218
1827
1.24
2.07
3.1
3.0
2.84
2.66
mg/l
0.53
191
1621
132
1041
1.30
2.06
1.3
1.2
10.06
10.72
u/ml
0.03
52
375
18
89
2.03
2.04
1.4
1.2
—
—
—
0
0
69
493
1.42
2.01
2.1
2.2
9.97
10.02
nmol/l
0.01
56
426
41
263
1.58
2.00
1.9
1.5
0.02
0.02
iu/ml
—
5
54
484
4408
1.19
1.92
5.7
3.8
520.54
403.83
e6/l
0.08
13
54
60
422
1.44
1.91
3.0
2.5
—
—
—
0
0
16
78
2.06
1.89
2.3
3.0
1.47
2.29
mmol/l
0.66
11
63
23
129
1.79
1.84
2.1
3.2
—
—
—
0
0
16
79
2.03
1.83
1.0
1.1
—
—
—
0
0
66
478
1.40
1.81
1.2
1.2
—
25.07
—
0
18
83
626
1.35
1.78
2.0
2.0
14.57
14.31
iu/l
0.03
65
478
34
215
1.59
1.78
13.3
9.4
117.20
386.93
iu/ml
—
5
29
67
893
0.73
1.75
2.6
3.3
775.42
973.20
ng/l
0.15
31
503
734
6967
1.22
1.75
14.1
10.8
3.92
3.90
mmol/l
0.86
703
6737
6
18
3.33
1.74
2.3
2.0
—
—
—
0
0
223
1909
1.21
1.72
1.8
1.7
102.60
98.34
pmol/l
0.65
124
997
668
6977
0.84
1.69
15.4
13.3
13.12
13.22
%
1.48
645
6847
169
1411
1.23
1.66
3.9
3.2
178.87
105.87
ug/g
0.87
127
1105
732
6957
1.21
1.66
14.1
10.8
139.69
139.60
mmol/l
0.59
706
6758
885
8600
1.39
1.66
18.2
15.0
263.60
266.17
e9/l
0.61
846
8301
182
1534
1.22
1.64
5.1
2.9
1.02
1.02
kg/l
0.24
16
228
5
14
3.57
1.61
1.0
1.6
—
—
—
0
0
5
14
3.57
1.61
1.0
1.6
—
—
—
0
0
314
2792
1.18
1.58
6.2
6.3
10.05
10.39
umol/l
0.23
286
2595
885
8609
1.38
1.55
18.1
14.9
4.57
4.59
e12/l
0.43
844
8291
0
43
0.00
1.52
0.0
1.5
—
—
—
0
0
708
6730
1.19
1.50
4.8
4.3
1.86
2.05
mu/l
0.53
650
6339
885
8615
1.36
1.49
18.4
15.0
134.55
134.79
g/l
0.23
865
8495
198
1701
1.20
1.47
2.4
2.6
58.12
56.45
u/l
0.09
182
1583
158
1328
1.22
1.47
3.1
2.9
1.02
1.05
mg/l
0.04
115
936
118
961
1.25
1.46
12.8
8.6
0.80
0.81
mmol/l
0.52
110
917
592
5552
1.16
1.46
3.4
3.0
5.52
5.54
mmol/l
0.09
533
5161
36
245
1.48
1.41
4.2
3.8
6.16
7.66
umol/l
0.43
27
201
490
4543
1.15
1.38
11.2
9.6
3.52
3.66
e9/l
0.90
432
3879
6
23
2.61
1.36
2.7
3.9
—
—
—
0
0
51
374
1.38
1.35
3.8
3.8
25.29
22.98
%
0.21
18
145
5
17
2.94
1.35
1.0
1.5
—
—
—
0
0
5
17
2.94
1.35
1.0
1.5
—
—
—
0
0
0
37
0.00
1.34
0.0
6.5
—
—
—
0
0
445
4104
1.15
1.34
9.6
7.6
33.15
32.45
%
0.73
417
3889
95
764
1.26
1.33
1.3
1.4
345.12
279.40
u/ml
0.27
85
705
131
1093
1.22
1.32
1.7
1.4
20.44
19.42
nmol/l
0.31
111
953
259
2298
1.17
1.32
8.0
6.2
37.32
37.94
g/l
1.18
239
2174
317
2858
1.16
1.30
1.6
1.7
2.83
2.22
u/ml
0.19
79
631
9
43
2.09
1.29
1.0
1.1
1347.00
1382.65
miu/ml
—
9
43
131
1096
1.22
1.29
4.6
3.5
2797.81
4882.25
umol/l
0.34
118
986
438
4044
1.14
1.28
9.4
7.4
52.41
52.99
%
0.50
409
3840
27
179
1.52
1.22
1.5
1.8
—
—
—
0
0
112
928
1.23
1.22
14.2
6.6
0.68
1.17
mmol/l
1.14
85
664
287
2582
1.15
1.21
1.5
1.6
1.78
1.81
g/l
0.14
168
1419
5
19
2.63
1.21
1.8
2.5
220.60
200.11
u/l
—
5
19
245
2180
1.16
1.20
2.6
2.4
—
—
—
0
0
14
78
1.80
1.19
1.2
1.4
—
—
—
0
0
520
4873
1.14
1.19
4.5
4.0
36.92
37.45
mmol/mol
0.53
466
4622
8
38
2.10
1.18
1.0
1.0
—
—
—
0
0
49
367
1.35
1.17
10.6
4.5
1.24
1.23
mmol/l
0.77
44
322
28
193
1.46
1.07
20.1
9.2
54.67
650.63
u/ml
—
6
19
12
66
1.82
1.07
5.0
6.6
—
40.44
—
0
9
15
240
0.62
1.06
1.1
1.1
—
—
—
0
0
16
97
1.65
1.05
2.5
2.1
—
—
—
0
0
256
2307
1.14
1.04
6.5
3.7
—
—
—
0
0
24
345
0.68
1.04
2.1
1.9
—
—
—
0
0
340
3124
1.13
1.03
12.3
8.6
1.22
1.22
mmol/l
1.41
299
2772
16
98
1.64
1.02
1.1
1.1
—
—
—
0
0
15
236
0.63
1.00
1.1
1.1
—
—
—
0
0
18
115
1.57
0.98
3.1
3.3
17.21
17.94
%
—
9
75
317
2908
1.13
0.98
14.6
8.7
1.23
1.22
mmol/l
1.21
291
2717
51
397
1.29
0.97
2.9
1.8
152.30
189.03
u/ml
0.50
20
202
781
7563
1.16
0.96
12.6
12.1
39.45
39.93
%
1.15
621
6441
16
100
1.60
0.95
5.8
3.7
26.63
24.46
umol/l
0.45
16
100
17
108
1.58
0.95
1.1
1.8
—
—
—
0
0
31
226
1.38
0.91
14.9
5.1
24.34
24.68
mmol/l
0.39
31
213
52
411
1.27
0.89
2.9
1.7
—
—
—
0
0
16
102
1.57
0.89
1.1
1.0
—
—
—
0
0
20
136
1.47
0.85
2.2
2.2
—
—
—
0
0
19
128
1.49
0.84
2.2
1.4
4.37
5.38
umol/l
0.58
19
119
18
120
1.50
0.84
1.9
1.9
0.56
3.89
ug/l
0.83
13
109
8
45
1.78
0.84
2.6
2.4
106.38
105.89
mmol/l
—
8
45
8
45
1.78
0.84
1.0
1.2
—
—
—
0
0
14
88
1.59
0.83
3.4
2.2
—
—
—
0
0
11
65
1.69
0.81
1.3
1.4
—
—
—
0
0
27
197
1.37
0.81
1.5
2.1
—
—
—
0
0
122
1064
1.16
0.80
3.6
4.3
4.78
8.84
mg/mmol
1.11
81
747
34
438
0.76
0.80
1.4
1.4
—
—
—
0
0
224
2038
1.12
0.79
2.5
2.3
—
—
—
0
0
0
25
0.00
0.79
0.0
2.2
—
7.06
—
0
18
0
25
0.00
0.79
0.0
2.2
—
4.11
—
0
20
0
25
0.00
0.79
0.0
2.2
—
1.34
—
0
20
0
25
0.00
0.79
0.0
2.2
—
4.12
—
0
14
0
25
0.00
0.79
0.0
2.2
—
1.61
—
0
18
0
25
0.00
0.79
0.0
2.2
—
3.08
—
0
20
0
25
0.00
0.79
0.0
2.2
—
1.23
—
0
19
395
3706
1.10
0.79
6.8
5.3
6.08
6.21
mmol/l
0.58
371
3420
6
33
1.81
0.78
1.7
1.1
—
—
—
0
0
11
66
1.67
0.77
1.3
1.4
—
—
—
0
0
0
27
0.00
0.77
0.0
2.2
—
0.63
—
0
18
6
34
1.76
0.76
4.8
5.4
—
—
—
0
0
747
7248
1.12
0.74
3.7
3.8
—
—
—
0
0
11
67
1.64
0.74
1.3
1.4
—
—
—
0
0
11
67
1.64
0.74
1.1
3.0
—
—
—
0
0
19
133
1.43
0.72
2.3
1.9
—
—
—
0
0
20
142
1.41
0.71
2.5
1.5
—
—
—
0
0
23
307
0.74
0.71
1.3
1.5
—
—
—
0
0
5
26
1.92
0.70
1.6
1.2
—
—
—
0
0
50
603
0.82
0.70
1.6
2.5
49.33
30.23
u/l
0.68
42
499
9
58
1.55
0.69
1.6
1.4
—
—
—
0
0
59
697
0.83
0.68
1.3
1.3
—
—
—
0
0
10
61
1.64
0.67
7.0
5.4
—
—
—
0
0
11
69
1.59
0.67
1.4
1.1
—
—
—
0
0
56
465
1.21
0.66
1.2
1.1
8.80
7.77
u/ml
0.18
41
320
7
43
1.62
0.66
2.1
2.6
—
1122.00
—
0
6
15
102
1.47
0.66
1.3
1.2
—
—
—
0
0
547
5242
1.09
0.66
3.7
3.1
1.12
1.18
mmol/l
1.11
495
4956
30
232
1.30
0.65
1.4
2.0
—
—
—
0
0
30
232
1.30
0.65
1.1
1.1
—
—
—
0
0
12
78
1.54
0.64
1.2
1.1
—
—
—
0
0
11
70
1.57
0.64
1.4
1.2
—
—
—
0
0
569
5469
1.09
0.62
3.9
3.3
1.48
1.46
mmol/l
0.41
515
5174
19
255
0.74
0.62
21.6
12.1
23.93
24.04
mmol/l
0.05
19
246
24
181
1.33
0.62
1.8
1.4
—
—
—
0
0
24
181
1.33
0.62
1.8
1.4
—
—
—
0
0
16
113
1.42
0.60
1.4
1.4
—
—
—
0
0
35
281
1.25
0.58
3.1
2.6
0.65
0.73
ug/l
0.37
17
157
19
140
1.36
0.57
1.3
1.2
—
—
—
0
0
6
36
1.66
0.56
1.5
1.9
4.47
1.62
nmol/l
—
6
26
129
1162
1.12
0.56
15.5
9.5
1.23
1.23
mmol/l
0.09
119
1103
9
59
1.52
0.54
3.1
4.7
—
—
—
0
0
9
59
1.52
0.54
3.1
4.7
—
—
—
0
0
10
65
1.54
0.54
1.3
1.4
—
—
—
0
0
9
61
1.47
0.53
1.2
1.4
—
—
—
0
0
573
5531
1.08
0.53
4.0
3.5
2.77
2.76
mmol/l
0.10
516
5211
40
331
1.21
0.52
1.4
1.6
2.25
3.28
mg/l
1.03
26
216
105
1158
0.89
0.52
4.9
3.1
3.58
3.85
e6/l
0.10
59
619
53
451
1.18
0.52
1.2
1.2
3.28
1.06
u/ml
0.66
36
281
10
66
1.51
0.51
1.3
1.4
—
—
—
0
0
10
66
1.51
0.51
1.3
1.4
—
—
—
0
0
12
83
1.44
0.51
1.2
1.2
—
—
—
0
0
12
83
1.44
0.51
1.2
1.2
—
—
—
0
0
135
1229
1.11
0.50
1.6
1.4
—
—
—
0
0
96
857
1.13
0.50
1.1
1.1
—
—
—
0
0
573
5541
1.07
0.49
4.0
3.4
4.60
4.58
mmol/l
0.20
520
5273
7
45
1.55
0.49
1.0
1.0
—
—
—
0
0
39
325
1.20
0.48
1.1
1.1
4.26
7.29
u/ml
—
8
48
12
84
1.43
0.48
1.2
1.2
—
—
—
0
0
26
207
1.26
0.48
1.2
1.1
3.97
4.53
u/ml
0.08
12
77
96
860
1.12
0.48
1.7
1.9
—
—
—
0
0
5
82
0.60
0.46
1.0
1.2
0.42
0.44
nmol/l
—
5
77
46
392
1.18
0.45
1.3
1.3
—
—
—
0
0
11
77
1.43
0.44
1.5
1.5
484.17
379.82
pmol/l
—
6
67
22
174
1.26
0.43
1.2
1.2
—
—
—
0
0
24
192
1.25
0.43
2.2
2.2
—
—
—
0
0
10
69
1.45
0.43
1.0
1.2
—
—
—
0
0
5
32
1.56
0.42
1.8
1.3
—
—
—
0
0
8
57
1.40
0.42
1.4
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
27
221
1.22
0.41
1.4
1.7
0.24
0.30
nmol/l
0.80
21
188
26
212
1.23
0.41
1.2
1.3
—
—
—
0
0
332
3168
1.07
0.41
1.8
1.9
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
402.43
—
0
18
38
440
0.85
0.40
12.7
10.3
0.39
0.44
mmol/l
0.02
29
342
15
114
1.31
0.39
2.6
2.1
—
—
—
0
0
37
429
0.85
0.39
1.5
1.9
—
—
—
0
0
54
608
0.88
0.39
2.1
1.9
—
—
—
0
0
8
61
1.31
0.39
1.0
1.2
—
—
—
0
0
20
159
1.26
0.39
1.3
1.6
—
—
—
0
0
38
438
0.86
0.38
12.7
10.3
5.34
5.11
kpa
0.90
38
416
5
36
1.38
0.38
1.0
1.2
—
—
—
0
0
38
437
0.86
0.37
12.6
10.3
14.12
14.77
kpa
0.38
38
417
8
114
0.70
0.37
1.0
1.8
—
—
—
0
0
8
115
0.69
0.37
1.1
1.1
110.50
118.79
%
—
8
107
6
41
1.46
0.36
1.7
1.2
—
—
—
0
0
6
41
1.46
0.36
4.2
2.4
20.49
26.68
ug/l
—
6
41
9
71
1.26
0.36
1.1
1.8
—
—
—
0
0
5
80
0.62
0.35
1.8
3.0
57.60
57.47
umol/l
—
5
73
207
2167
0.94
0.35
4.5
3.7
61.35
29.89
u/l
0.56
198
2073
6
43
1.39
0.35
1.5
1.9
—
—
—
0
0
27
226
1.19
0.34
1.1
1.1
—
—
—
0
0
26
305
0.84
0.33
1.6
1.3
—
—
—
0
0
52
462
1.13
0.32
1.5
1.4
—
—
—
0
0
28
325
0.85
0.32
1.7
1.7
—
—
—
0
0
11
83
1.32
0.31
1.3
1.2
—
—
—
0
0
11
83
1.32
0.31
1.3
1.2
—
—
—
0
0
11
141
0.77
0.30
1.0
1.1
—
—
—
0
0
159
1497
1.07
0.30
1.7
1.7
1.18
1.31
mmol/l
1.89
134
1341
33
376
0.87
0.30
1.2
1.3
214.33
247.04
miu/ml
0.23
18
179
7
54
1.29
0.30
1.1
2.3
19.57
21.82
ug/l
—
7
47
37
325
1.14
0.28
16.1
7.3
126.05
129.38
g/l
0.48
37
315
55
497
1.11
0.27
1.4
1.2
5.71
2.95
u/ml
0.39
37
285
10
76
1.31
0.27
1.6
1.5
—
—
—
0
0
120
1124
1.07
0.27
15.1
8.0
1.32
1.40
mmol/l
0.11
103
902
17
203
0.83
0.27
2.2
1.9
3.28
5.91
iu/l
—
5
69
8
66
1.21
0.26
1.4
3.9
—
3.45
—
0
7
8
66
1.21
0.26
1.0
1.1
—
—
—
0
0
21
178
1.18
0.25
1.6
1.5
—
—
—
0
0
21
243
0.86
0.24
1.0
1.1
0.06
0.49
u/ml
—
9
83
6
82
0.73
0.24
1.2
1.5
—
—
—
0
0
41
368
1.11
0.24
2.8
1.7
—
—
—
0
0
12
96
1.25
0.23
1.2
1.5
—
—
—
0
0
20
170
1.17
0.23
1.3
1.4
388.50
343.36
ug/g
—
6
86
5
37
1.35
0.23
2.0
2.2
—
—
—
0
0
68
728
0.92
0.23
1.4
1.5
—
—
—
0
0
26
294
0.88
0.23
1.1
1.1
12.11
5.50
u/ml
0.60
17
140
32
284
1.13
0.22
1.3
1.7
—
—
—
0
0
39
351
1.11
0.22
15.8
12.4
1.09
1.21
inr
—
8
58
5
41
1.21
0.22
1.0
1.1
—
—
—
0
0
5
41
1.21
0.22
1.0
1.1
—
—
—
0
0
5
42
1.19
0.21
1.8
2.3
4.78
3.03
nmol/l
—
5
42
67
621
1.08
0.21
1.6
1.8
—
—
—
0
0
22
191
1.15
0.21
2.1
2.1
—
—
—
0
0
48
439
1.09
0.20
1.1
1.2
2.77
3.44
u/ml
0.16
14
127
11
133
0.82
0.20
5.6
3.5
—
—
—
0
0
6
49
1.22
0.20
1.2
1.2
—
—
—
0
0
128
1217
1.05
0.20
2.4
2.0
—
—
—
0
0
82
770
1.07
0.19
2.4
2.3
9470.59
6518.99
u/l
0.20
24
264
72
761
0.94
0.18
2.1
2.2
2.41
2.42
mmol/l
0.43
67
649
85
800
1.06
0.18
7.8
5.0
4.92
6.37
umol/l
1.38
68
676
10
81
1.23
0.18
1.2
2.0
—
—
—
0
0
7
60
1.16
0.17
1.0
1.9
118.71
120.82
%
—
7
60
12
100
1.20
0.17
1.4
1.2
—
—
—
0
0
12
100
1.20
0.17
1.1
1.2
—
—
—
0
0
7
62
1.12
0.17
1.1
1.0
—
—
—
0
0
16
183
0.87
0.17
2.6
2.7
134.00
134.80
g/l
0.06
11
148
37
339
1.09
0.16
1.4
1.4
—
—
—
0
0
15
129
1.16
0.16
4.3
8.3
1.33
1.53
%
0.49
15
115
15
129
1.16
0.16
3.5
2.9
677.13
697.83
e6/l
—
8
23
34
368
0.92
0.16
1.4
1.6
—
—
—
0
0
37
340
1.09
0.15
1.4
1.4
—
—
—
0
0
37
340
1.09
0.15
1.4
1.4
—
—
—
0
0
37
341
1.08
0.14
1.4
1.4
—
—
—
0
0
29
264
1.10
0.14
3.2
3.8
22.40
6.66
ug/l
0.36
21
193
109
1044
1.04
0.14
1.8
1.5
1.39
1.37
%
0.15
97
953
10
84
1.19
0.13
1.1
1.6
—
—
—
0
0
19
210
0.90
0.13
1.7
1.5
—
—
—
0
0
11
94
1.17
0.12
3.6
3.7
3.86
3.75
mmol/l
0.50
11
79
14
123
1.13
0.11
1.1
1.6
—
—
—
0
0
66
629
1.05
0.11
1.7
1.4
—
—
—
0
0
5
43
1.16
0.10
1.0
1.1
—
—
—
0
0
5
43
1.16
0.10
1.0
1.1
—
—
—
0
0
5
44
1.13
0.10
1.2
2.0
—
—
—
0
0
5
44
1.13
0.10
1.2
2.0
—
—
—
0
0
5
44
1.13
0.10
1.2
2.0
—
—
—
0
0
5
45
1.11
0.09
1.0
1.1
—
—
—
0
0
5
45
1.11
0.09
1.0
1.1
—
—
—
0
0
11
96
1.14
0.09
4.1
5.4
1.84
1.82
ug/l
0.01
11
96
5
48
1.04
0.09
1.2
2.8
1459.40
948.92
u/ml
—
5
48
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
147
1430
1.03
0.09
2.7
2.2
—
—
—
0
0
6
53
1.13
0.09
1.0
1.0
—
—
—
0
0
15
135
1.11
0.09
1.1
1.1
—
—
—
0
0
10
87
1.15
0.09
1.1
1.7
—
—
—
0
0
6
55
1.09
0.08
1.0
1.2
—
—
—
0
0
171
1734
0.98
0.08
7.3
5.6
90.33
90.68
%
0.07
164
1705
5
63
0.79
0.08
1.0
1.7
—
0.71
u/ml
—
0
21
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
68
1.02
0.07
1.0
1.2
—
—
—
0
0
193
1951
0.98
0.07
6.0
3.6
0.50
0.26
e6/l
0.32
158
1445
39
372
1.04
0.06
2.6
2.8
81.63
78.94
ml/min/173m2
0.17
16
141
12
109
1.10
0.05
2.1
2.2
—
—
—
0
0
22
207
1.06
0.05
1.6
1.5
—
—
—
0
0
37
382
0.96
0.05
1.4
1.5
—
—
—
0
0
57
553
1.03
0.04
1.4
1.5
292.59
357.02
mu/l
1.66
49
510
41
420
0.97
0.04
7.2
7.1
92.88
95.71
%
0.37
41
406
214
2111
1.01
0.03
6.7
3.6
26.04
69.12
e6/l
0.74
178
1591
34
349
0.97
0.03
11.7
10.6
118.62
122.88
g/l
0.72
34
337
12
128
0.93
0.03
2.7
4.4
3.24
9.62
u/ml
0.64
12
119
60
609
0.98
0.03
15.7
8.1
106.97
105.02
mmol/l
1.32
60
596
13
138
0.94
0.03
5.0
3.4
10.13
9.13
%
—
8
118
20
190
1.05
0.03
5.6
9.0
23.52
24.07
mmol/l
0.33
20
175
13
137
0.94
0.02
28.5
10.8
73.14
65.86
%
1.70
13
137
76
746
1.01
0.02
1.1
1.3
50.09
180.68
iu/ml
6.43
20
272
119
1174
1.01
0.01
4.6
3.0
0.81
0.94
e6/l
0.30
75
636
21
202
1.04
0.01
41.0
4.8
23.29
23.45
mmol/l
0.13
21
185
42
411
1.02
0.01
1.2
1.2
—
—
—
0
0
23
228
1.00
0.00
4.2
2.9
3.83
11.03
e6/l
0.79
18
180
63
625
1.00
0.00
1.7
1.9
—
—
—
0
0
26
261
0.99
0.00
1.1
1.1
7.79
9.55
u/ml
0.22
15
139
13
127
1.02
0.00
1.2
1.3
—
—
—
0
0
7
79
0.88
0.00
2.4
1.8
12.57
13.10
%
—
7
79
0
9
0.00
0.00
0.0
1.2
—
10.33
—
0
9
0
5
0.00
0.00
0.0
7.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
24.20
—
0
6
0
7
0.00
0.00
0.0
4.1
—
0.43
—
0
7
7
77
0.90
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
29.40
—
0
5
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.8
—
0.25
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.0
—
8.54
—
0
8
Mortality – FinRegistry
↥Association
Association between endpoint K11_OVERJET and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have K11_OVERJET.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: K11_OVERJET – Overjet
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data