Isolated proteinuria with specified morphological lesion

N14_ISOLPROTEINURIA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N06#
  • Cause of death: ICD-10 N06#

2 out of 7 registries used, show all original rules.

458

4. Check minimum number of events

None

458

5. Include endpoints

None

458

6. Filter based on genotype QC (FinnGen only)

408

Control definitions (FinnGen only)

Control exclude
N14_GLOMERULAR

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N00-N08
Name in latin
Proteinuria isolata cum laesione morphologica specificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2409 1167 1221
Only index persons 2118 1030 1088
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.03
Only index persons 0.04 0.04 0.04
Median age at first event (years)
Whole population 57.83 56.49 59.16
Only index persons 55.61 53.58 57.53

-FinnGen-

Key figures

All Female Male
Number of individuals 408 201 207
Unadjusted period prevalence (%) 0.08 0.07 0.09
Median age at first event (years) 57.50 53.60 61.28

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
429
Matched controls
4290
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N06.9
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, unspecified
+∞
270.4
230
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
114.1
202.2
104
12
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
73.4
176.8
97
17
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
89.8
173.4
92
13
N18.8
ICD-10 Finland
Other chronic renal failure
50.5
138.9
82
20
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
16.6
138.2
133
113
A11CC03
ATC
alfacalcidol; systemic
35.4
124.4
81
28
A12AA04
ATC
calcium carbonate; oral
60.2
109.7
62
12
L04AA06
ATC
mycophenolic acid; systemic
38.1
102.9
65
20
127
Kela drug reimbursment
Transplant complication
53.5
96.8
56
12
TK800
NOMESCO Finland
Hemodialysis
36.1
96.7
62
20
B03XA02
ATC
darbepoetin alfa; parenteral
31.5
89.7
60
22
N06.0
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, minor glomerular abnormality
+∞
84.2
78
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
47.0
84.0
50
12
R80
ICD-10 Finland
Isolated proteinuria
142.2
78.0
81
7
L04AA01
ATC
[U] ciclosporin
36.7
67.8
43
13
L04AD01
ATC
ciclosporin; systemic
25.6
67.0
48
21
C03CA01
ATC
furosemide; systemic
5.2
63.6
243
865
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
150.0
61.7
64
5
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
8.7
61.3
87
122
KA1AE
NOMESCO Finland
Kidney ultrasound examination
14.7
54.6
51
39
Z94.0
ICD-10 Finland
Kidney transplant status
205.3
53.3
54
*
205
Kela drug reimbursment
Chronic hypertension
4.6
52.8
200
687
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
+∞
52.2
49
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.2
50.5
133
341
Z49.0
ICD-10 Finland
Preparatory care for dialysis
115.5
47.9
51
5
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
183.8
47.9
49
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
82.2
46.1
51
7
N06.1
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, focal and segmental glomerular lesions
+∞
45.6
43
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
238.3
42.7
43
*
C08CA01
ATC
amlodipine; oral
3.9
42.3
257
1188
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
73.3
41.0
46
7
C09AA02
ATC
enalapril; systemic
4.1
40.4
151
499
137
Kela drug reimbursment
Uraemia requiring dialysis
146.6
38.4
40
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
+∞
38.1
36
*
M04AA01
ATC
allopurinol; systemic
4.5
37.9
115
324
L04AD02
ATC
tacrolimus; systemic
90.5
37.5
41
5
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
+∞
37.0
35
*
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
+∞
37.0
35
*
V03AE01
ATC
polystyrene sulfonate; oral
75.2
36.7
41
6
N18.0
ICD-10 Finland
End-stage renal disease
138.6
36.3
38
*
B05DB
ATC
Hypertonic solutions
195.9
35.3
36
*
B05DA
ATC
Isotonic solutions
134.6
35.3
37
*
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
101.0
34.3
37
*
N06.2
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, diffuse membranous glomerulonephritis
+∞
32.7
31
*
WW200
NOMESCO Finland
Immunization
11.8
32.4
34
31
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
178.3
32.2
33
*
Z49.2
ICD-10 Finland
Other dialysis
122.8
32.2
34
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.0
32.1
62
118
N06.8
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, other
+∞
31.7
30
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.3
31.0
95
267
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
55.9
30.8
36
7
H02AB04
ATC
methylprednisolone; systemic
3.9
30.2
111
355
C08CA02
ATC
felodipine; oral
4.6
29.6
81
208
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.1
29.1
206
984
N04.0
ICD-10 Finland
Nephrotic syndrome, minor glomerular abnormality
+∞
28.4
27
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
7.0
27.9
45
71
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
27.4
26
*
C02AC05
ATC
moxonidine; oral
6.0
27.4
52
97
L01BA01
ATC
methotrexate; systemic
8.1
27.2
38
51
N19
ICD-10 Finland
Unspecified kidney failure
6.8
26.7
44
71
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.4
26.1
56
117
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
276.4
26.0
26
*
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
9.0
25.2
32
38
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
8.0
25.0
35
47
N03.1
ICD-10 Finland
Chronic nephritic syndrome, focal and segmental glomerular lesions
+∞
24.2
23
*
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
44.3
23.9
29
7
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
253.6
23.9
24
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.9
23.2
33
45
N04.2
ICD-10 Finland
Nephrotic syndrome, diffuse membranous glomerulonephritis
+∞
23.1
22
*
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
88.4
22.9
25
*
M10.9
ICD-10 Finland
Gout, unspecified
4.5
22.6
61
154
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
22.1
264
1590
P01BA02
ATC
hydroxychloroquine; oral
4.2
22.1
66
180
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
121.2
21.8
23
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
7.0
21.6
34
52
C10AA05
ATC
atorvastatin; oral
2.6
21.5
234
1341
3025
Kela drug reimbursment
Calcium carbonate
63.4
21.1
24
*
V03AE02
ATC
sevelamer; oral
220.3
20.8
21
*
ZX120
NOMESCO Finland
Intravenous
3.7
20.6
73
224
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.7
20.5
50
116
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
+∞
19.9
19
*
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
19.9
19
*
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
+∞
19.9
19
*
N03.2
ICD-10 Finland
Chronic nephritic syndrome, diffuse membranous glomerulonephritis
+∞
19.9
19
*
V03AE03
ATC
lanthanum carbonate; oral
110.2
19.7
21
*
196
Kela drug reimbursment
Paricalcitol and cinacalcet
110.2
19.7
21
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.4
19.4
40
80
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
6.2
19.1
34
59
H05BX01
ATC
cinacalcet; oral
36.2
19.1
24
7
C09CA01
ATC
losartan; oral
2.6
18.9
155
764
N03.0
ICD-10 Finland
Chronic nephritic syndrome, minor glomerular abnormality
+∞
18.9
18
*
N06.3
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, diffuse mesangial proliferative glomerulonephritis
+∞
18.9
18
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.1
18.9
42
90
C08CA13
ATC
lercanidipine; oral
3.0
18.8
100
394
TK820
NOMESCO Finland
Peritoneal dialysis
198.3
18.7
19
*
L04AX01
ATC
azathioprine; systemic
5.7
18.1
35
66
I10
ICD-10 Finland
Essential (primary) hypertension
2.6
17.9
305
2088
321
Kela drug reimbursment
Paricalcitol and cinacalcet
33.0
17.2
22
7
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
23.0
17.0
24
11
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
93.8
16.7
18
*
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
34.8
15.9
20
6
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.8
15.6
51
147
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
15.2
150
793
A10BK01
ATC
dapagliflozin; oral
3.5
15.1
57
181
C10AA01
ATC
simvastatin; oral
2.2
15.0
207
1259
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
14.9
69
249
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
+∞
14.7
14
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.7
14.6
50
149
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.7
14.5
35
80
B03XA01
ATC
erythropoietin; parenteral
17.8
14.4
22
13
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.1
13.7
62
220
H02AB06
ATC
prednisolone; systemic
2.2
13.6
237
1560
N03.5
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangiocapillary glomerulonephritis
+∞
13.6
13
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.2
13.5
152
842
RD210, ,
NOMESCO Finland
12.0
13.5
24
21
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
13.4
99
455
C07AG02
ATC
carvedilol; oral
3.7
13.4
45
132
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.7
13.3
45
133
J01MA14
ATC
moxifloxacin; systemic
3.1
13.2
62
225
L04AA13
ATC
[U] leflunomide
9.8
13.2
26
28
R4190
NOMESCO Finland
Nutritional therapy
4.6
13.1
32
74
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
13.0
133
706
B01AA03
ATC
warfarin; systemic
2.5
13.0
99
462
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
12.8
12.7
22
18
KBV00
NOMESCO Finland
Insertion of stent into ureter
33.1
12.7
16
5
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
12.7
119
609
E66.00
ICD-10 Finland
Metabolic syndrome
3.8
12.6
40
113
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
+∞
12.6
12
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
133.8
12.5
13
*
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
133.8
12.5
13
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.6
12.3
78
332
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
12.3
68
270
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
5.7
12.2
23
42
A07EC01
ATC
sulfasalazine; oral, rectal
3.2
12.0
50
169
K65.0
ICD-10 Finland
Acute peritonitis
13.0
11.7
20
16
E66.8
ICD-10 Finland
Other obesity
3.9
11.6
35
95
Z3231
NOMESCO Finland
Registered nurse
2.1
11.6
140
789
N06.4
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, diffuse endocapillary proliferative glomerulonephritis
+∞
11.5
11
*
N05.9
ICD-10 Finland
Unspecified nephritic syndrome, unspecified
+∞
11.5
11
*
R50.9
ICD-10 Finland
Fever, unspecified
2.5
11.4
85
390
M01CB01
ATC
sodium aurothiomalate; parenteral
12.3
11.4
20
17
WX202
NOMESCO Finland
Supraclavicular plexus blockade
10.5
11.1
21
21
A46
ICD-10 Finland
Erysipelas
2.4
11.1
86
402
U14
ICPC
Kidney symptom/complaint
9.2
10.9
22
25
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
10.8
97
484
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
5.5
10.7
21
40
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
10.5
146
864
N06.5
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, diffuse mesangiocapillary glomerulonephritis
+∞
10.5
10
*
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
+∞
10.5
10
*
N04.5
ICD-10 Finland
Nephrotic syndrome, diffuse mesangiocapillary glomerulonephritis
+∞
10.5
10
*
7910X
ICD-9 Finland
Nonspecific findings on examination of urine, Proteinuria[PROTEINURIA NUD]
+∞
10.5
10
*
58209
ICD-8 Finland
Chronic nephritis, Unspecified
+∞
10.5
10
*
J01MA12
ATC
levofloxacin; systemic
2.2
10.4
99
505
JN4AD
NOMESCO Finland
Body CT examination
2.5
10.2
68
296
C07AB07
ATC
bisoprolol; oral
1.9
10.1
232
1623
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
10.1
96
489
N02AX02
ATC
tramadol; systemic, rectal
1.9
10.0
205
1382
WZC30
NOMESCO Finland
Teaching
2.3
9.9
91
457
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
9.7
124
708
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.2
9.7
39
129
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.5
9.6
63
272
ZXD05
NOMESCO Finland
Urgent procedure
2.0
9.6
146
887
WW500
NOMESCO Finland
Blood transfusion
3.7
9.5
31
89
N18.2
ICD-10 Finland
Chronic kidney disease, stage 2
30.8
9.4
12
*
L04AX03
ATC
methotrexate; systemic
2.6
9.4
57
236
B01AB05
ATC
enoxaparin; parenteral
2.0
9.4
152
941
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
+∞
9.4
9
*
N04.3
ICD-10 Finland
Nephrotic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
9.4
9
*
C07FB02
ATC
metoprolol and felodipine; systemic
4.9
9.4
21
45
C02EA02, ,
ATC
3.9
9.3
28
76
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.7
9.2
54
220
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
9.1
132
785
J01MA02
ATC
ciprofloxacin; systemic
1.9
9.0
181
1199
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
9.0
94
496
M13.9
ICD-10 Finland
Arthritis, unspecified
2.9
9.0
45
169
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.4
9.0
33
103
O12.1
ICD-10 Finland
Gestational proteinuria
24.6
9.0
12
5
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
8.9
108
602
TQW80
NOMESCO Finland
Local dermatologic skincare
5.1
8.9
19
39
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.5
8.8
61
270
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.0
8.8
41
148
C02CA01
ATC
prazosin; oral
7.9
8.7
19
25
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.4
8.7
62
278
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
8.6
73
353
I50.9
ICD-10 Finland
Heart failure, unspecified
2.3
8.6
74
360
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
9.3
8.6
17
19
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.1
8.5
98
535
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
20.5
8.5
12
6
R4110
NOMESCO Finland
Physiotherapy
1.9
8.5
133
810
M01AE01
ATC
ibuprofen; systemic, rectal
0.5
8.5
296
3480
ZXE00
NOMESCO Finland
One hour or less
1.9
8.5
173
1147
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
8.5
120
706
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.9
8.5
41
151
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
91.8
8.4
9
*
U88
ICPC
Glomerulonephritis/nephrosis
91.8
8.4
9
*
A12AA12
ATC
[U] calcium acetate
+∞
8.4
8
*
N06
ICD-10 Finland
Isolated proteinuria with specified morphological lesion
+∞
8.4
8
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.5
8.2
28
83
TK810
NOMESCO Finland
Hemofiltration
34.0
8.1
10
*
306
Kela drug reimbursment
Erythropoietin and darbepoetin
34.0
8.1
10
*
A10AC01
ATC
insulin (human); parenteral
2.7
8.0
46
185
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
4.6
8.0
19
43
C10AX09
ATC
ezetimibe; oral
2.1
8.0
89
480
R4180
NOMESCO Finland
Podiatric therapy
8.0
7.9
17
22
C03AA03
ATC
hydrochlorothiazide; oral
2.6
7.9
47
193
RS221, ,
NOMESCO Finland
8.7
7.9
16
19
C09CA06
ATC
candesartan; oral
1.9
7.8
116
691
XW000
NOMESCO Finland
Bone marrow biopsy
3.3
7.8
29
91
B01AB10
ATC
tinzaparin; parenteral
2.3
7.8
60
278
WX892
NOMESCO Finland
Monitored bed care
2.7
7.8
43
170
E66.01
ICD-10 Finland
Obesity due to excess calories
2.5
7.8
49
207
L88
ICPC
Rheumatoid/seropositive arthritis
3.5
7.6
26
77
A10AB05
ATC
insulin aspart; parenteral
2.6
7.6
46
190
UJF32
NOMESCO Finland
Coloscopy
1.9
7.6
122
745
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.8
7.6
39
148
XPX08
NOMESCO Finland
Intraoperative flow measurement
10.3
7.6
14
14
SPAT1262
SPAT
Handing over of treatment supplies
2.1
7.6
83
444
J01DB01
ATC
cefalexin; oral
2.1
7.6
358
3031
SPAT1255
SPAT
Intravenous administration of medicine
2.9
7.6
37
137
A10BH05
ATC
linagliptin; oral
3.1
7.6
32
109
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.9
7.5
115
691
WX204
NOMESCO Finland
Axillary plexus blockaced
3.5
7.5
26
78
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
7.5
59
276
C07AB02
ATC
metoprolol; systemic
2.0
7.4
95
537
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.1
7.4
20
50
R2110
NOMESCO Finland
Giving the first information
3.1
7.4
31
105
N18
ICD-10 Finland
Chronic kidney disease
9.6
7.3
14
15
N00.0
ICD-10 Finland
Acute nephritic syndrome, Minor glomerular abnormality
+∞
7.3
7
*
TK824
NOMESCO Finland
Replacement of peritoneal dialysis catheter extension tube
+∞
7.3
7
*
N05.8
ICD-10 Finland
Unspecified nephritic syndrome, other
+∞
7.3
7
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.0
7.3
33
117
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.7
7.2
23
65
J01FF01
ATC
clindamycin; systemic
1.8
7.2
128
805
D64.9
ICD-10 Finland
Anaemia, unspecified
2.3
7.2
56
260
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.6
7.2
24
70
L01AA01
ATC
cyclophosphamide; systemic
30.6
7.2
9
*
UKC02
NOMESCO Finland
Cystoscopy
2.0
7.2
81
438
212
Kela drug reimbursment
Gout
6.2
7.1
18
30
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.4
7.1
53
242
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.3
7.1
18
43
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
7.0
47
204
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.5
7.0
45
192
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
6.9
158
1071
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
3.2
6.9
27
88
C08CA05
ATC
nifedipine; systemic
2.8
6.8
35
133
B07.9
ICD-10 Finland
Verruca simplex
3.6
6.8
22
63
M10.3
ICD-10 Finland
Gout due to impairment of renal function
17.0
6.8
10
6
C03DA01
ATC
spironolactone; oral
2.2
6.8
61
302
H02AB07
ATC
prednisone; oral
2.1
6.7
67
345
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
12.5
6.6
11
9
H26.3
ICD-10 Finland
Drug-induced cataract
12.5
6.6
11
9
TQW99
NOMESCO Finland
Other minor procedure on skin
2.8
6.6
32
118
AA1AD
NOMESCO Finland
CT of head and brain
1.8
6.6
133
868
A12BA01
ATC
potassium chloride; oral
3.3
6.5
25
80
J01CF02
ATC
cloxacillin; systemic
5.5
6.5
18
34
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
6.5
86
490
N25.0
ICD-10 Finland
Renal osteodystrophy
70.9
6.4
7
*
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
70.9
6.4
7
*
R06.0
ICD-10 Finland
Dyspnoea
1.8
6.4
129
841
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
6.4
65
338
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
6.3
56
275
E78.29
ICD-10 Finland
Other mixed hyperlipidaemia
11.3
6.3
11
10
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
18.3
6.3
9
5
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
18.3
6.3
9
5
R31
ICD-10 Finland
Unspecified haematuria
2.2
6.3
54
262
N04.4
ICD-10 Finland
Nephrotic syndrome, diffuse endocapillary proliferative glomerulonephritis
+∞
6.3
6
*
N04.89
ICD-10 Finland
Nephrotic syndrome, other
+∞
6.3
6
*
V03AE04
ATC
calcium acetate and magnesium carbonate; systemic
+∞
6.3
6
*
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
27.1
6.2
8
*
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
27.1
6.2
8
*
A02BC01
ATC
omeprazole; systemic
1.8
6.2
121
778
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.6
6.2
20
57
Z2446
NOMESCO Finland
Social worker
2.6
6.2
35
140
RF210, ,
NOMESCO Finland
3.9
6.1
18
48
N02BE01
ATC
paracetamol; systemic, rectal
2.2
6.1
385
3422
C10AA03
ATC
pravastatin; oral
2.5
6.1
38
160
OAB50, ,
SPAT
2.4
6.0
42
186
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
6.0
91
542

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
132
34
55.63
223.91
4.0
2.5
2.44
0.76
g/24h
8.07
106
23
278
494
14.15
176.45
20.1
4.3
1.14
1.02
mmol/l
9.11
272
456
194
277
11.96
142.21
9.9
3.1
149.82
75.93
ng/l
7.52
182
243
125
124
13.81
117.05
3.8
4.0
69.86
83.87
mg/l
0.11
94
107
125
124
13.81
117.05
3.8
4.0
47.07
42.56
mg/l
0.11
95
107
119
113
14.19
114.47
3.8
3.6
2.47
2.03
ratio
0.25
66
66
75
33
27.33
105.61
1.9
2.5
—
—
—
0
0
144
254
8.03
84.43
3.4
2.7
—
—
—
0
0
218
582
6.58
84.28
7.7
2.2
2.15
2.33
g/l
4.11
211
539
79
5
192.96
77.99
1.6
1.2
—
—
—
0
0
259
878
5.92
74.63
8.0
2.6
3.66
4.91
e6/l
1.10
251
799
71
66
12.69
67.89
10.3
2.7
15.20
8.60
pmol/l
2.46
71
66
306
1276
5.88
66.65
13.7
3.9
74.67
6.01
mg/mmol
23.18
288
791
302
1246
5.81
66.63
11.3
3.3
403.32
37.72
mg/l
23.22
283
800
56
37
17.26
65.12
1.0
1.1
—
—
u/ml
—
0
0
308
1318
5.74
64.19
11.5
3.2
6.47
7.88
mmol/l
8.20
298
1108
296
1261
5.35
61.01
10.3
3.3
20.52
105.87
e6/l
0.99
273
966
152
381
5.63
60.33
10.4
3.0
7.36
7.39
ph
9.58
112
211
218
743
4.93
59.46
8.2
2.8
478.76
541.65
mosm/kgh2o
5.25
205
650
146
369
5.48
57.07
11.4
3.0
1.27
1.98
mmol/l
1.61
129
319
251
984
4.74
56.36
6.5
2.8
384.57
345.73
umol/l
6.36
242
862
186
595
4.75
54.15
2.7
2.0
29.55
29.46
s
0.06
186
578
64
71
10.42
53.87
8.3
3.0
—
—
—
0
0
95
172
6.81
52.73
2.6
2.1
1.67
1.57
g/l
0.33
88
157
258
1088
4.44
51.15
9.8
3.1
0.31
0.43
e6/l
0.52
235
796
301
1438
4.66
49.80
12.4
3.9
93.53
100.21
e6/l
0.05
279
1015
245
1024
4.25
48.50
8.8
3.1
—
0.00
estimate
—
0
6
264
1169
4.27
48.00
17.0
3.9
7.39
7.40
ph
4.38
234
829
350
1905
5.55
47.86
27.0
6.7
1.22
1.21
mmol/l
0.85
321
1653
103
249
5.13
41.32
7.7
3.2
7.40
7.42
ph
5.01
96
207
120
329
4.68
41.27
13.0
8.3
—
—
—
0
0
56
75
8.44
40.43
1.7
1.8
—
—
—
0
0
172
647
3.77
37.77
5.2
3.1
0.81
0.82
mmol/l
0.41
166
623
70
132
6.14
36.74
1.3
1.2
—
—
—
0
0
304
1666
3.83
36.64
4.8
2.4
71.40
76.85
nmol/l
2.67
298
1488
117
347
4.26
35.89
4.9
2.8
73.13
71.57
e9/l
0.18
89
257
142
489
3.85
35.22
3.1
1.5
—
—
—
0
0
53
78
7.61
35.19
3.2
1.2
176.04
154.15
au/ml
0.60
16
23
253
1268
3.43
34.45
10.5
6.1
—
—
—
0
0
66
130
5.82
32.98
7.5
3.8
955.38
207.80
mg/l
3.01
53
49
54
88
6.88
32.61
3.1
1.3
—
—
—
0
0
310
1799
3.61
32.42
12.9
6.4
8.63
8.86
%
0.81
302
1689
38
41
10.07
32.27
1.1
1.3
—
—
—
0
0
309
1796
3.58
32.10
12.8
6.3
2.90
2.77
%
0.53
302
1681
308
1790
3.56
31.92
12.9
6.3
0.71
0.68
%
0.33
300
1668
108
332
4.01
31.18
3.5
2.4
9.15
10.84
g/l
3.45
103
308
159
634
3.40
30.91
3.0
1.6
—
—
—
0
0
307
1805
3.46
30.69
12.6
6.3
59.13
57.81
%
1.15
302
1716
145
553
3.45
30.18
1.5
1.4
536.92
518.08
titre
0.03
26
125
308
1828
3.43
30.02
13.1
6.4
25.87
27.29
%
1.50
303
1736
320
1949
3.53
29.76
12.5
6.3
0.05
0.04
e9/l
1.64
294
1674
319
1944
3.50
29.53
12.5
6.3
0.62
0.59
e9/l
1.50
293
1669
37
12
33.58
28.64
28.7
49.1
84.41
132.08
ug/l
1.59
32
12
324
2015
3.48
28.53
12.8
6.4
0.20
0.19
e9/l
0.47
299
1756
33
7
50.85
27.86
7.2
1.3
—
—
—
0
0
336
2167
3.54
27.19
15.6
10.0
4.49
4.15
e9/l
2.05
311
1893
152
635
3.16
26.75
7.0
3.0
1.46
2.01
e6/l
0.68
101
309
315
1966
3.27
26.73
9.3
3.9
0.00
0.00
estimate
-0.00
108
413
316
1977
3.27
26.68
12.9
6.3
2.28
1.92
e9/l
0.40
296
1749
47
82
6.31
26.46
1.9
1.2
219.90
255.11
u/ml
0.30
30
45
318
2003
3.27
26.40
9.4
3.9
0.08
0.78
estimate
0.44
100
391
315
1983
3.21
25.98
9.5
3.9
0.00
8.32
estimate
0.80
110
421
70
177
4.53
25.98
2.6
1.9
11.21
8.69
iu/ml
0.23
15
44
366
2542
3.99
25.21
13.0
4.4
—
1.51
—
0
6
156
681
3.03
25.19
6.6
2.9
0.67
0.90
e6/l
0.78
106
355
209
1085
2.81
24.21
7.1
4.3
—
—
—
0
0
54
120
5.00
23.37
1.7
1.2
—
—
—
0
0
87
278
3.67
23.29
2.0
1.5
1.54
1.47
g/l
0.06
79
257
32
16
21.51
22.04
1.9
1.4
—
—
—
0
0
93
322
3.41
21.92
8.2
5.4
0.17
0.14
%
0.11
36
94
282
1773
2.72
21.39
20.4
12.7
1.24
1.23
inr
0.11
252
1463
259
1569
2.64
21.08
7.7
3.5
6.29
6.20
ph
0.54
150
876
151
706
2.76
20.82
3.3
1.9
—
—
—
0
0
94
342
3.24
20.34
8.3
5.2
1.11
0.83
%
0.39
37
115
91
327
3.26
20.08
7.6
5.1
0.53
0.40
%
0.33
34
103
276
1751
2.62
19.98
7.9
2.9
209.38
129.16
ug/l
4.37
268
1635
92
340
3.17
19.33
8.0
5.7
0.15
0.18
%
0.09
34
95
36
66
5.86
19.17
8.7
3.2
2.39
2.41
mmol/l
0.01
23
44
200
1108
2.51
19.11
4.5
3.1
—
—
—
0
0
266
1687
2.52
18.82
28.7
11.9
0.00
0.00
e9/l
0.06
232
1390
126
572
2.70
18.06
2.8
1.9
—
—
—
0
0
180
982
2.44
17.41
3.2
2.1
2.88
2.94
mg/l
0.15
168
852
24
12
21.10
16.61
2.6
1.9
0.60
0.60
mmol/l
0.05
24
12
28
22
13.53
16.39
2.6
2.0
743.95
430.17
ml
2.54
22
12
336
2466
2.67
16.08
8.8
4.6
254.67
914.18
e6/l
—
9
38
189
1082
2.33
16.08
8.0
3.2
0.02
0.08
estimate
0.39
99
336
39
91
4.61
15.82
3.4
2.2
393.48
80.31
ug/min
2.21
29
55
90
366
2.85
15.74
7.5
7.2
1.27
1.31
mmol/l
0.11
90
358
292
2040
2.35
15.09
8.4
6.8
10.91
11.49
umol/l
0.26
286
1952
314
2269
2.43
14.92
10.6
4.8
6.81
6.66
mmol/l
0.75
306
2143
201
1211
2.24
14.82
3.0
2.1
144.20
204.45
u/l
1.45
193
1145
18
5
37.46
14.55
1.0
1.0
—
—
—
0
0
85
349
2.79
14.53
4.2
2.0
0.00
0.04
estimate
0.49
25
77
26
46
5.95
14.31
1.4
1.2
—
—
—
0
0
79
319
2.81
13.90
2.3
1.5
—
—
—
0
0
183
1105
2.14
12.98
9.7
3.9
0.14
0.00
estimate
1.48
77
386
228
1504
2.10
12.73
8.8
3.8
0.03
0.01
estimate
0.26
100
344
17
7
25.19
12.55
1.0
1.0
—
—
—
0
0
17
7
25.19
12.55
1.0
1.1
—
—
—
0
0
194
1232
2.05
11.72
3.8
2.5
63.49
65.54
u/l
0.14
187
1155
59
223
2.91
11.66
6.4
2.4
0.69
0.62
%
1.10
59
223
25
52
5.04
11.57
3.2
2.2
33.36
32.98
pg
0.22
25
52
85
389
2.48
11.52
2.1
2.0
336.22
382.55
nmol/l
1.16
79
363
118
628
2.21
11.27
2.3
1.7
1264.83
1172.78
nmol/l
0.40
102
478
53
193
2.99
11.18
4.3
2.1
0.00
0.02
estimate
0.49
22
65
50
177
3.07
11.07
8.8
3.3
—
—
—
0
0
21
39
5.61
10.98
4.9
1.6
10.24
10.72
%
0.21
21
39
69
292
2.62
10.97
11.2
3.4
—
—
—
0
0
181
1146
2.00
10.81
2.2
1.7
19.85
20.97
nmol/l
0.44
171
969
35
102
3.65
10.53
1.7
1.2
—
—
—
0
0
197
1295
1.96
10.47
7.5
3.3
2.32
2.36
mmol/l
2.34
190
1167
44
150
3.15
10.38
3.1
2.8
—
—
—
0
0
91
451
2.29
10.23
6.7
7.5
7.41
7.42
ph
0.41
53
267
147
879
2.02
10.19
9.2
5.1
—
—
—
0
0
34
100
3.61
10.09
4.5
3.1
2.39
2.59
index
0.08
23
54
91
455
2.27
10.01
6.7
7.4
10.86
11.98
kpa
1.59
86
439
18
17
11.00
9.87
3.1
1.7
202.31
75.44
ng/l
1.38
18
17
191
1265
1.92
9.73
3.7
2.4
—
—
—
0
0
72
329
2.43
9.71
1.7
1.4
—
—
—
0
0
17
16
11.01
9.36
1.6
1.5
3.82
0.78
u/field
—
11
9
18
20
9.34
9.11
1.6
1.9
—
—
—
0
0
86
439
2.20
8.93
2.5
1.7
—
—
—
0
0
87
449
2.18
8.78
6.8
7.5
0.59
0.87
mmol/l
0.29
72
373
175
1177
1.82
8.12
4.5
3.3
5094.06
1185.90
ng/l
4.53
163
1000
231
1688
1.80
8.12
2.6
2.1
100.27
95.11
pmol/l
1.05
145
898
16
18
9.19
8.10
1.3
1.3
174.00
167.26
mmol/24h
0.07
16
18
171
1145
1.82
8.03
11.2
6.4
—
—
—
0
0
43
168
2.73
7.96
5.8
4.1
1.60
1.54
%
0.20
43
156
135
843
1.88
7.91
2.0
1.4
2.75
2.52
g/l
0.51
100
519
25
75
3.48
7.22
1.3
2.0
—
—
—
0
0
236
1790
1.71
6.82
3.9
2.8
—
—
estimate
—
0
0
17
41
4.28
6.61
1.2
1.1
—
—
—
0
0
204
1499
1.69
6.54
6.3
3.9
43.00
73.59
ng/l
0.39
169
1093
71
380
2.04
6.43
7.5
8.0
113.86
121.59
g/l
2.09
71
372
120
775
1.76
6.08
1.9
1.8
464.36
24080196.64
pmol/l
0.69
105
652
30
114
2.75
5.87
1.7
1.4
223.22
298.39
ug/g
1.20
25
67
36
151
2.51
5.80
6.5
4.4
0.89
0.87
%
0.14
36
139
181
1319
1.64
5.80
4.1
3.2
47.19
32.98
u/l
0.50
171
1256
16
41
4.01
5.76
1.8
1.4
—
—
nmol/l
—
0
0
12
17
7.23
5.47
1.3
1.0
52.08
84.00
mg/l
0.97
12
12
16
43
3.83
5.41
3.0
2.2
89.69
90.40
%
0.17
16
43
16
34
4.85
5.35
1.1
1.1
—
—
—
0
0
46
225
2.17
5.25
5.2
3.9
—
—
—
0
0
42
200
2.22
5.12
1.3
1.3
—
—
—
0
0
381
3422
2.01
5.07
6.8
4.3
1.65
1.29
mmol/l
3.27
367
3146
15
41
3.75
4.97
1.3
1.4
0.27
0.19
nmol/l
—
10
30
17
51
3.43
4.93
1.1
1.3
—
—
—
0
0
16
38
4.33
4.87
1.3
1.2
—
—
—
0
0
30
126
2.48
4.84
1.2
1.2
—
97.50
—
0
12
25
96
2.70
4.82
6.9
4.6
—
—
—
0
0
16
47
3.50
4.79
1.2
1.2
—
—
—
0
0
82
506
1.77
4.77
2.4
2.3
188.12
117.84
ug/g
0.70
73
410
77
467
1.79
4.74
2.9
2.9
7.04
7.24
umol/l
0.07
64
418
17
53
3.30
4.66
2.8
2.7
1.18
1.19
mmol/l
0.21
17
53
17
53
3.30
4.66
2.8
2.7
105.12
105.64
mmol/l
0.13
17
53
17
53
3.30
4.66
2.8
2.7
3.84
3.98
mmol/l
0.68
17
53
11
18
6.24
4.63
1.0
2.5
1021.18
805.72
u/ml
0.22
11
18
7
5
14.20
4.59
1.0
1.2
—
—
—
0
0
12
23
5.34
4.49
2.3
4.3
16.10
16.11
%
0.00
12
23
63
369
1.83
4.34
2.4
1.7
—
—
—
0
0
18
61
3.04
4.33
1.7
1.3
—
—
—
0
0
36
175
2.15
4.19
2.4
2.3
—
—
—
0
0
398
3680
2.13
4.12
50.9
18.6
139.46
139.67
mmol/l
1.05
398
3615
342
3028
1.64
4.08
51.1
20.1
14.11
13.63
%
7.90
342
3003
8
10
8.13
4.07
1.4
1.4
—
—
—
0
0
23
93
2.56
4.03
2.7
1.4
7006.28
14102.47
e6/l
0.53
18
68
7
7
10.14
4.02
1.0
1.0
—
—
—
0
0
9
14
6.54
4.00
1.4
2.8
38.31
41.97
g/l
—
9
14
393
3624
2.01
3.99
44.2
16.0
17.47
24.16
mg/l
7.11
363
2977
17
59
2.96
3.94
9.4
5.4
14.24
11.08
mg/l
2.15
17
54
19
71
2.75
3.87
2.3
1.4
0.55
0.63
g/l
0.25
14
61
146
1090
1.51
3.87
1.7
1.4
—
—
—
0
0
12
28
4.38
3.84
1.9
2.4
2.00
1.86
u/field
—
7
14
14
38
3.77
3.83
1.1
1.4
277.44
276.46
mosm/kgh2o
—
9
26
301
2616
1.50
3.63
5.6
4.2
—
14431.14
—
0
7
103
727
1.55
3.49
6.2
3.7
95.09
274.60
ng/l
1.61
88
571
11
27
4.15
3.41
1.6
1.8
41.14
36.78
%
0.33
11
27
119
874
1.50
3.34
2.2
1.8
1.67
1.27
mg/l
0.35
100
690
124
923
1.48
3.25
1.5
1.3
1.93
1.50
u/ml
0.28
45
247
18
72
2.57
3.25
1.1
1.1
—
—
—
0
0
19
80
2.44
3.10
1.1
1.1
—
—
—
0
0
71
475
1.59
3.02
1.3
1.3
—
—
—
0
0
15
57
2.69
2.99
1.5
2.6
—
—
—
0
0
16
63
2.60
2.99
2.6
1.4
—
—
—
0
0
384
3572
1.72
2.99
8.0
5.1
1.38
1.44
mmol/l
1.91
373
3305
59
378
1.65
2.98
3.8
2.6
36.00
35.39
u/l
0.04
53
316
8
17
4.77
2.93
1.3
1.2
—
—
—
0
0
50
308
1.71
2.93
3.7
2.4
6.17
6.04
ph
0.42
41
202
9
22
4.16
2.89
4.8
2.9
0.78
0.95
index
—
9
22
8
18
4.51
2.80
2.0
1.0
1356.00
1425.22
miu/ml
—
8
18
384
3584
1.68
2.79
8.1
5.2
4.46
4.60
mmol/l
1.90
374
3333
371
3436
1.59
2.76
11.3
6.4
40.72
39.35
mmol/mol
1.77
361
3229
5
6
8.41
2.75
1.8
1.3
—
—
—
0
0
6
10
6.07
2.70
4.2
5.1
57.50
51.90
%
—
6
10
6
10
6.07
2.70
1.0
1.5
182.33
53.40
nmol/24h
—
6
10
8
19
4.27
2.69
3.9
1.5
—
—
—
0
0
11
36
3.11
2.58
3.1
1.4
0.39
0.37
g/l
—
6
29
11
36
3.11
2.58
3.1
1.4
5.95
6.40
g/l
—
6
30
11
36
3.11
2.58
3.1
1.4
3.08
2.89
g/l
—
6
30
15
62
2.47
2.57
1.4
1.5
—
—
—
0
0
15
62
2.47
2.57
1.4
1.5
—
—
—
0
0
15
62
2.47
2.57
1.4
1.5
—
—
—
0
0
15
62
2.47
2.57
1.4
1.5
—
—
—
0
0
313
2818
1.41
2.55
4.9
4.3
14.84
14.86
pmol/l
0.04
297
2578
67
461
1.54
2.53
1.4
1.3
—
—
—
0
0
387
3636
1.66
2.52
8.6
5.9
2.48
2.70
mmol/l
5.21
377
3374
32
181
1.83
2.51
1.2
1.3
—
—
—
0
0
24
123
2.01
2.50
1.2
1.3
455.75
233.59
miu/ml
—
5
55
12
45
2.71
2.47
1.0
1.2
—
—
—
0
0
11
38
2.94
2.43
3.1
1.4
—
—
—
0
0
10
34
2.99
2.29
1.5
1.1
—
—
—
0
0
12
47
2.60
2.29
2.9
4.2
—
—
—
0
0
401
3821
1.76
2.23
54.9
20.9
138.27
77.52
umol/l
20.55
401
3784
18
337
0.51
2.09
1.2
1.4
—
—
—
0
0
14
63
2.26
2.03
1.7
1.3
2.13
3.42
u/ml
—
8
26
21
112
1.92
2.00
2.6
2.1
3703.17
5995.32
u/l
—
6
41
72
530
1.43
1.96
1.3
1.3
—
—
—
0
0
10
39
2.60
1.95
1.2
1.6
—
—
—
0
0
8
27
3.00
1.94
1.1
1.1
—
—
—
0
0
6
16
3.79
1.94
1.2
1.3
—
—
—
0
0
16
78
2.09
1.93
1.2
1.2
19.61
20.04
u/l
0.03
16
66
46
311
1.54
1.90
2.6
2.6
14.40
6.64
ug/l
0.50
41
278
19
100
1.94
1.88
1.2
1.2
—
—
—
0
0
8
28
2.89
1.87
1.9
1.9
1018.38
1050.13
e6/l
—
8
23
188
1615
1.29
1.86
2.4
1.9
1.68
1.38
mmol/l
1.33
165
1345
175
1490
1.29
1.85
2.3
2.1
—
—
—
0
0
16
81
2.01
1.77
2.1
2.0
3.94
4.88
mmol/24h
0.64
16
74
13
61
2.17
1.73
1.9
1.5
—
—
—
0
0
12
55
2.22
1.69
2.2
3.2
—
—
—
0
0
13
63
2.10
1.61
5.2
3.0
4.40
4.26
e9/l
0.07
13
63
8
32
2.53
1.60
1.1
1.1
—
—
—
0
0
5
126
0.39
1.52
2.0
1.1
0.88
0.91
g/l
—
5
126
356
3363
1.34
1.51
6.1
5.3
2.01
1.92
mu/l
0.67
343
3098
388
3720
1.45
1.47
37.7
14.1
—
—
—
0
0
26
165
1.61
1.44
2.5
1.9
—
—
—
0
0
7
29
2.44
1.39
2.1
1.3
—
—
—
0
0
64
491
1.36
1.39
1.8
1.4
—
—
—
0
0
10
47
2.15
1.34
3.2
2.3
—
—
—
0
0
9
43
2.12
1.31
1.2
1.2
—
—
—
0
0
16
91
1.79
1.30
5.8
2.7
60.12
58.78
%
0.17
16
91
10
48
2.11
1.28
2.6
3.2
14.05
3.67
nmol/l
—
10
48
8
35
2.31
1.27
2.3
2.3
—
—
—
0
0
6
25
2.42
1.24
2.2
4.1
6.82
8.08
mmol/l
—
6
25
16
93
1.75
1.23
4.0
1.6
—
—
—
0
0
28
189
1.52
1.22
1.8
1.6
0.29
0.34
mg/l
0.24
11
82
5
19
2.65
1.22
1.0
1.4
184.40
152.05
nmol/l
—
5
19
8
40
2.02
1.12
1.0
1.2
—
—
—
0
0
50
384
1.34
1.11
1.4
1.5
—
—
—
0
0
8
41
1.97
1.09
1.1
2.0
—
—
—
0
0
7
32
2.21
1.08
1.3
1.1
98.71
112.34
pmol/l
—
7
32
7
33
2.14
1.06
1.1
1.1
—
—
—
0
0
7
33
2.14
1.06
2.3
1.6
40.43
33.65
ng/l
—
7
33
54
425
1.31
1.02
1.7
1.7
—
—
—
0
0
80
663
1.25
1.02
1.3
1.3
37.22
13.74
u/ml
0.59
25
250
7
36
1.96
0.97
1.3
1.5
—
—
—
0
0
9
50
1.82
0.97
1.0
1.1
—
—
—
0
0
401
3911
1.39
0.90
61.4
24.4
92.13
91.27
fl
2.79
401
3879
401
3914
1.38
0.86
61.6
24.4
4.29
4.50
e12/l
9.16
396
3844
401
3914
1.38
0.86
61.3
24.3
30.34
30.42
pg
0.34
401
3881
40
316
1.29
0.77
1.4
1.2
—
—
—
0
0
10
159
0.62
0.73
2.0
1.8
—
—
—
0
0
7
41
1.72
0.70
1.1
1.2
—
—
—
0
0
7
43
1.64
0.67
1.3
1.5
—
—
—
0
0
99
880
1.16
0.63
9.1
4.0
1.02
1.02
kg/l
0.17
79
582
8
51
1.58
0.60
3.1
2.0
10.57
10.60
mmol/l
—
8
51
81
714
1.17
0.58
1.3
1.3
90.13
32.17
iu/ml
0.75
24
221
15
107
1.42
0.56
2.1
1.4
—
—
—
0
0
14
193
0.72
0.54
1.3
1.1
—
—
—
0
0
18
136
1.34
0.50
3.6
1.4
—
—
—
0
0
18
136
1.34
0.50
3.6
1.4
—
—
—
0
0
148
1374
1.12
0.49
4.6
5.5
2.14
2.48
ug/l
0.45
137
1250
18
137
1.33
0.48
3.6
1.4
—
—
—
0
0
31
374
0.82
0.47
1.4
1.5
—
—
—
0
0
17
129
1.33
0.46
3.6
1.4
—
—
—
0
0
8
57
1.41
0.42
2.1
1.9
—
—
—
0
0
5
33
1.52
0.41
1.6
1.4
—
—
—
0
0
17
133
1.29
0.39
3.7
1.4
—
—
—
0
0
264
2552
1.09
0.36
5.2
3.4
67.19
51.15
u/l
1.17
252
2416
15
118
1.28
0.34
1.3
1.2
—
—
—
0
0
6
87
0.69
0.33
1.2
1.1
—
—
—
0
0
7
54
1.30
0.30
1.3
1.3
—
—
—
0
0
8
106
0.75
0.29
16.8
10.0
—
—
—
0
0
82
763
1.09
0.27
3.6
3.0
2.49
2.45
mmol/l
1.52
74
697
44
398
1.12
0.25
3.1
4.4
4.50
35.60
ug/l
0.94
33
335
5
38
1.32
0.23
1.4
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
18.42
—
0
11
0
11
0.00
0.21
0.0
1.3
—
5543.40
—
0
5
0
10
0.00
0.21
0.0
1.0
—
57.60
—
0
10
0
12
0.00
0.21
0.0
2.7
—
5.82
—
0
12
5
43
1.16
0.21
1.8
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
13.84
—
0
9
15
128
1.18
0.18
1.6
1.9
158.93
224.15
pmol/l
2.23
15
119
22
247
0.88
0.17
1.1
1.2
93.50
142.83
u/ml
—
8
103
7
61
1.15
0.17
1.6
1.1
—
—
—
0
0
7
61
1.15
0.17
1.6
1.1
—
—
—
0
0
7
62
1.13
0.17
1.4
1.3
—
—
—
0
0
303
2983
1.05
0.17
48.2
20.9
329.83
332.59
g/l
6.03
303
2974
9
82
1.10
0.15
1.9
1.8
—
—
—
0
0
17
151
1.13
0.13
1.0
1.1
—
—
—
0
0
22
242
0.90
0.13
1.2
1.2
—
—
—
0
0
86
832
1.04
0.10
3.8
3.2
1.18
0.78
ug/l
0.92
67
535
141
1441
0.97
0.09
5.4
3.1
—
—
—
0
0
5
64
0.78
0.08
6.4
3.5
10.80
30.20
u/ml
—
5
64
10
88
1.14
0.08
1.2
1.3
3.80
23.49
e6/l
—
5
65
10
90
1.11
0.05
1.2
1.4
387.80
1437.44
e6/l
—
5
68
17
162
1.05
0.02
1.6
1.9
41.06
39.43
nmol/l
0.09
17
155
351
3503
1.01
0.01
7.4
5.2
6.15
5.96
mmol/l
1.59
331
3219
10
102
0.98
0.00
1.1
1.1
—
—
—
0
0
5
58
0.86
-0.00
1.2
5.3
269.20
356.17
umol/l
—
5
52
0
7
0.00
-0.00
0.0
1.4
—
42.71
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.6
—
7.15
—
0
9
0
7
0.00
-0.00
0.0
1.4
—
1.89
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
61
0.98
-0.00
1.0
1.1
—
—
—
0
0
8
80
1.00
-0.00
1.3
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
8.08
—
0
5
0
7
0.00
-0.00
0.0
1.7
—
59.29
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
17.97
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_ISOLPROTEINURIA and mortality.

Females

Parameter HR [95% CI] p-value
N14_ISOLPROTEINURIA 2.374 [1.89, 2.99] < 0.001
Birth year 0.997 [0.99, 1.01] 0.498

During the follow-up period (1.1.1998 — 31.12.2019), 298 out of 1035 females with N14_ISOLPROTEINURIA died.

Males

Parameter HR [95% CI] p-value
N14_ISOLPROTEINURIA 2.47 [2.05, 2.98] < 0.001
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 335 out of 1068 males with N14_ISOLPROTEINURIA died.

Mortality risk

Mortality risk for people of age

years, who have N14_ISOLPROTEINURIA.

N-year risk Females Males
1 0.206% 0.406%
5 1.226% 2.37%
10 3.842% 6.592%
15 7.307% 12.895%
20 13.146% 21.264%

Relationships between endpoints

Index endpoint: N14_ISOLPROTEINURIA – Isolated proteinuria with specified morphological lesion

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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