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Proteinuria and renal glomerular damage; focal glomerulonephritis

Endpoint Browser

N14_PROTEINURIA_AND_RENAL_GLOMERULAR_DAMAGE_FOCAL_GLOMERULONEPHRITIS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N06.1#
  • Cause of death: ICD-10 — N06.1#

2 out of 7 registries used, show all original rules.

49

4. Check minimum number of events

None

49

5. Include endpoints

None

49

6. Filter based on genotype QC (FinnGen only)

41

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 41 21 20
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 56.15 57.00 55.26

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
34
60
23.04
18.11
27.7
6.0
1.15
1.04
mmol/l
1.17
34
55
13
0
+∞
14.34
1.9
0.0
—
—
—
0
0
20
43
7.83
10.05
14.8
2.6
1.31
2.28
mmol/l
0.58
20
33
35
142
8.83
8.89
12.9
3.4
6.67
8.19
mmol/l
1.68
35
120
16
22
10.88
8.15
16.1
2.2
23.31
24.58
mmol/l
0.85
16
22
7
0
+∞
7.49
8.7
0.0
—
—
—
0
0
28
107
5.63
7.16
6.9
3.3
401.04
334.40
umol/l
2.06
28
95
12
12
13.32
7.08
3.4
1.2
—
—
—
0
0
29
116
5.61
6.97
12.5
3.0
—
—
estimate
—
0
0
10
8
15.77
6.46
15.4
4.3
20.68
19.70
pmol/l
—
10
8
6
0
+∞
6.39
1.0
0.0
—
—
—
0
0
6
0
+∞
6.39
1.0
0.0
—
—
—
0
0
15
32
6.62
5.70
14.5
4.7
—
—
—
0
0
11
16
8.81
5.36
5.2
2.2
23.08
25.01
mmol/l
0.63
11
16
10
13
9.62
5.19
12.2
3.9
—
—
—
0
0
33
171
5.00
5.18
28.5
7.0
1.22
1.21
mmol/l
0.29
33
161
34
185
4.99
5.12
19.7
5.3
34.65
35.54
g/l
0.54
34
174
17
55
4.46
5.03
12.1
3.4
1.95
3.83
e6/l
0.38
11
28
10
14
8.92
4.98
7.6
2.1
94.03
89.73
%
—
10
14
10
15
8.31
4.79
2.1
1.3
—
—
—
0
0
16
52
4.31
4.67
5.1
1.6
—
—
—
0
0
10
16
7.77
4.61
7.7
2.2
9.44
7.99
kpa
—
10
16
7
6
13.57
4.44
8.0
1.3
71.49
59.88
%
—
7
6
8
10
9.50
4.27
7.9
4.0
16.92
15.57
%
—
8
10
13
34
5.02
4.14
17.1
7.1
1.22
1.22
mmol/l
0.02
13
28
24
113
3.54
4.01
9.6
5.0
—
—
—
0
0
6
5
13.61
3.88
3.2
9.6
1943.33
808.60
mg
—
6
5
30
171
3.50
3.55
12.0
3.3
6.47
6.19
ph
0.51
17
87
10
24
5.10
3.46
12.2
5.7
23.29
24.68
mmol/l
—
10
24
38
265
4.72
3.46
17.3
4.6
—
—
—
0
0
12
35
4.35
3.45
6.8
4.2
0.99
1.38
mmol/l
0.81
12
35
17
70
3.36
3.41
4.8
1.8
—
—
—
0
0
33
206
3.59
3.25
14.8
3.7
0.00
0.00
estimate
-0.00
13
47
9
21
5.12
3.20
8.0
2.9
0.83
0.65
%
—
9
21
12
39
3.86
3.09
1.8
1.3
—
—
—
0
0
9
22
4.88
3.09
8.0
2.8
1.54
1.90
%
—
9
22
33
211
3.43
3.02
15.5
3.8
0.00
0.00
estimate
-0.00
13
46
7
13
6.19
3.00
3.3
4.1
—
—
—
0
0
33
213
3.36
2.93
15.5
3.7
0.00
0.00
estimate
—
10
44
10
30
4.02
2.83
4.6
1.6
—
—
—
0
0
6
10
6.76
2.80
1.8
2.7
1.28
1.32
mmol/l
—
6
10
10
31
3.88
2.74
11.3
3.6
0.49
0.22
e6/l
—
10
31
10
32
3.75
2.65
1.2
3.8
—
—
—
0
0
22
121
2.68
2.51
4.8
3.2
—
—
—
0
0
10
34
3.52
2.48
1.5
4.1
64.65
64.99
g/l
—
10
34
5
8
6.89
2.44
1.0
5.9
—
—
—
0
0
5
8
6.89
2.44
1.0
1.3
—
—
—
0
0
24
140
2.62
2.41
14.1
6.6
—
—
—
0
0
5
10
5.49
2.13
1.2
1.3
—
—
—
0
0
12
52
2.81
2.10
8.9
6.3
102.17
104.52
mmol/l
1.29
12
52
16
82
2.51
2.03
5.1
2.0
—
—
—
0
0
12
53
2.75
2.03
3.2
2.2
—
—
—
0
0
6
16
4.18
2.01
12.5
5.6
7.39
7.41
ph
—
6
16
18
99
2.41
1.96
6.7
4.1
106.06
90.04
%
2.35
18
99
6
18
3.70
1.81
16.2
2.3
—
—
—
0
0
5
13
4.20
1.76
13.0
4.7
4.74
4.92
kpa
—
5
13
5
13
4.20
1.76
13.0
4.7
9.66
8.32
kpa
—
5
13
6
19
3.49
1.73
2.7
5.3
22.05
25.36
mmol/l
—
6
19
34
260
2.47
1.70
11.3
4.8
—
601.33
—
0
6
20
122
2.20
1.67
3.1
2.4
—
—
—
0
0
5
14
3.89
1.66
1.2
4.8
—
—
—
0
0
18
107
2.17
1.58
3.4
2.2
2.52
2.67
mg/l
0.13
18
97
26
179
2.14
1.57
9.7
3.0
211.53
111.40
ug/l
1.48
26
171
28
199
2.17
1.55
19.6
6.5
60.00
59.39
%
0.10
28
190
19
117
2.12
1.52
14.2
4.0
0.00
0.00
estimate
—
7
44
5
16
3.39
1.48
1.0
1.1
—
—
—
0
0
19
120
2.05
1.40
1.6
1.5
—
—
—
0
0
27
198
1.98
1.28
21.3
6.9
0.64
0.67
%
0.11
27
184
22
151
1.94
1.26
2.3
1.9
—
—
—
0
0
27
199
1.96
1.25
21.3
6.9
2.94
2.66
%
0.27
27
186
20
134
1.92
1.22
2.6
3.0
64.20
57.25
u/l
0.37
20
122
27
200
1.94
1.22
21.4
6.9
8.98
8.21
%
0.99
27
188
27
202
1.90
1.16
21.4
6.9
26.42
26.12
%
0.05
27
192
18
119
1.88
1.12
11.8
3.2
0.00
0.00
estimate
-0.00
13
38
9
49
2.05
1.07
3.3
1.3
—
—
—
0
0
7
37
2.06
0.99
2.3
1.2
—
—
—
0
0
19
133
1.77
0.96
16.4
7.5
—
—
—
0
0
6
28
2.32
0.96
11.2
3.2
—
—
—
0
0
24
181
1.74
0.93
2.1
2.1
112.77
96.10
pmol/l
1.26
13
86
8
46
1.90
0.88
2.6
1.5
—
—
—
0
0
8
46
1.90
0.88
1.1
1.7
—
—
—
0
0
21
155
1.69
0.86
13.8
3.6
0.00
0.00
estimate
-0.00
12
40
9
53
1.88
0.82
4.3
4.9
1.93
1.77
%
—
9
47
7
38
2.00
0.78
1.7
1.5
—
—
—
0
0
9
60
1.63
0.59
2.6
2.4
324.00
170.01
ug/g
—
9
46
13
94
1.55
0.54
1.9
2.0
688.54
468.41
pmol/l
0.69
13
81
7
47
1.58
0.51
5.7
1.8
5.03
5.08
e9/l
—
7
42
17
133
1.46
0.49
2.5
1.7
24.62
20.38
nmol/l
0.32
17
108
6
90
0.61
0.49
1.5
2.8
2.41
2.46
mmol/l
—
6
77
0
16
0.00
0.42
0.0
1.0
—
1.47
—
0
16
0
17
0.00
0.41
0.0
1.1
—
0.96
—
0
17
16
128
1.40
0.40
6.4
3.6
—
—
—
0
0
6
85
0.66
0.37
4.3
2.8
1.08
0.82
ug/l
—
6
55
6
42
1.50
0.37
2.3
7.1
101.33
121.24
g/l
—
6
42
6
43
1.46
0.37
16.8
3.8
—
—
—
0
0
6
43
1.46
0.37
2.5
7.1
90.65
95.93
%
—
6
43
6
45
1.39
0.35
1.5
1.5
—
—
—
0
0
13
103
1.38
0.33
1.2
1.7
2.99
2.78
g/l
—
8
57
13
104
1.36
0.31
14.8
6.6
—
—
—
0
0
8
61
1.38
0.31
1.5
1.4
—
430.77
—
0
13
18
155
1.28
0.25
7.0
3.0
2.31
2.35
mmol/l
0.45
18
141
11
134
0.76
0.25
5.9
5.4
2.32
1.86
ug/l
0.23
11
118
21
186
1.25
0.23
3.5
2.9
—
—
estimate
—
0
0
5
42
1.21
0.22
1.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
2.77
—
0
6
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
8
96
0.80
0.15
1.4
1.7
2.14
2.11
mg/l
—
8
79
6
57
1.06
0.09
1.3
1.2
—
—
—
0
0
36
349
1.19
0.08
13.2
6.8
42.13
40.21
mmol/mol
0.52
36
331
14
145
0.95
0.00
5.8
3.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
11.3
—
40.29
—
0
7
0
7
0.00
0.00
0.0
5.9
—
267.29
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
48
1.05
-0.00
1.6
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
6.52
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
6.4
—
105.25
—
0
8
0
8
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
63.78
—
0
9
0
8
0.00
-0.00
0.0
6.4
—
9.75
—
0
8

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: N14_PROTEINURIA_AND_RENAL_GLOMERULAR_DAMAGE_FOCAL_GLOMERULONEPHRITIS – Proteinuria and renal glomerular damage; focal glomerulonephritis

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).