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Proteinuria and renal glomerular damage; focal glomerulonephritis

Endpoint Browser

N14_PROTEINURIA_AND_RENAL_GLOMERULAR_DAMAGE_FOCAL_GLOMERULONEPHRITIS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N06.1#
  • Cause of death: ICD-10 — N06.1#

2 out of 7 registries used, show all original rules.

42

4. Check minimum number of events

None

42

5. Include endpoints

None

42

6. Filter based on genotype QC (FinnGen only)

40

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: unknown.

No upset table: unknown.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 40 21 19
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 55.68 56.36 54.92

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
33
49
27.39
19.35
22.8
6.0
1.15
1.05
mmol/l
0.90
33
44
10
0
+∞
10.88
1.7
0.0
—
—
—
0
0
20
44
7.77
9.84
8.5
2.5
23.75
21.51
%
0.34
20
37
32
116
8.39
9.41
10.7
3.1
6.77
7.95
mmol/l
1.10
32
96
15
14
15.88
9.23
13.1
2.2
23.57
24.20
mmol/l
0.24
15
14
17
24
11.10
8.61
7.2
2.5
5.62
4.57
kpa
0.87
17
24
18
33
8.72
7.80
10.4
2.6
5.84
5.57
kpa
0.59
18
33
26
90
5.96
7.62
5.8
3.3
380.12
4482.59
umol/l
0.49
26
78
20
55
6.03
7.58
8.2
2.3
12.31
12.65
umol/l
0.08
20
50
7
0
+∞
7.50
8.7
0.0
—
—
—
0
0
27
102
5.61
7.01
10.9
2.8
—
—
—
0
0
10
7
18.16
6.79
5.8
2.7
—
—
—
0
0
10
7
18.16
6.79
12.1
3.4
—
—
—
0
0
10
8
15.87
6.47
3.6
1.3
—
—
—
0
0
6
0
+∞
6.40
1.0
0.0
—
—
—
0
0
6
0
+∞
6.40
1.0
0.0
—
—
—
0
0
32
148
5.88
6.29
21.4
6.5
1.22
1.22
mmol/l
0.18
32
136
27
110
5.07
6.19
21.5
5.7
7.39
7.40
ph
—
10
22
10
9
14.08
6.17
5.8
2.7
9.52
7.93
kpa
—
10
9
10
10
12.66
5.90
10.7
4.4
—
—
—
0
0
9
8
13.86
5.59
3.4
3.0
23.97
24.50
mmol/l
—
9
8
32
161
5.15
5.33
16.3
5.0
33.89
35.50
g/l
1.21
32
153
10
13
9.68
5.20
1.6
1.4
—
—
—
0
0
12
24
6.55
4.77
14.6
4.1
—
—
—
0
0
14
43
4.38
4.37
5.1
1.5
—
—
—
0
0
16
57
3.92
4.08
4.3
1.7
—
—
—
0
0
37
244
5.32
4.04
14.4
4.3
—
—
—
0
0
30
169
3.71
3.72
15.6
4.7
0.00
0.00
estimate
-0.00
12
38
6
6
11.37
3.61
2.0
3.2
—
—
—
0
0
6
6
11.37
3.61
1.8
4.0
—
—
—
0
0
6
6
11.37
3.61
1.8
3.3
1.28
1.43
mmol/l
—
6
6
30
172
3.60
3.55
12.1
3.5
0.00
0.00
estimate
-0.00
12
38
30
173
3.57
3.50
12.1
3.5
0.00
0.00
estimate
—
10
36
21
98
3.29
3.47
8.8
4.9
—
—
—
0
0
26
140
3.25
3.35
10.2
3.2
—
5.89
—
0
9
9
20
5.42
3.33
5.4
2.7
113.67
129.35
g/l
—
9
20
11
33
4.14
3.10
1.5
1.3
—
—
—
0
0
6
9
7.55
2.97
5.5
1.4
—
—
—
0
0
9
25
4.29
2.77
4.3
1.6
—
—
—
0
0
7
15
5.37
2.72
6.1
2.9
1.71
1.62
%
—
7
15
7
15
5.37
2.72
6.1
2.9
0.81
0.69
%
—
7
15
28
170
2.94
2.72
15.9
7.9
—
—
—
0
0
29
181
2.95
2.65
16.2
6.8
0.05
0.04
e9/l
0.88
29
160
6
11
6.15
2.64
13.0
3.1
—
—
—
0
0
21
111
2.78
2.63
4.0
3.0
—
—
—
0
0
9
27
3.95
2.57
6.4
3.7
1.07
1.51
mmol/l
—
9
27
6
13
5.19
2.36
3.3
3.8
—
—
—
0
0
32
218
2.97
2.36
17.6
11.4
4.74
4.38
e9/l
0.31
32
190
5
9
6.13
2.28
3.0
2.8
0.86
1.40
mmol/l
—
5
9
5
9
6.13
2.28
2.8
2.8
5.64
6.81
mmol/l
—
5
9
7
19
4.20
2.26
4.9
2.9
26.44
24.24
mmol/l
—
7
19
28
182
2.62
2.20
16.8
6.7
0.60
0.57
e9/l
0.40
28
161
15
72
2.69
2.20
4.7
1.7
—
—
—
0
0
28
184
2.57
2.12
16.8
6.8
1.80
1.83
e9/l
0.04
28
170
23
140
2.42
2.03
7.7
2.7
202.43
106.97
ug/l
1.13
23
131
5
11
4.99
2.00
13.0
4.5
9.66
7.96
kpa
—
5
11
5
11
4.99
2.00
13.0
4.5
4.74
5.03
kpa
—
5
11
16
83
2.50
1.98
5.7
3.9
107.75
90.07
%
2.35
16
83
18
99
2.43
1.97
10.3
3.2
—
—
—
0
0
11
47
2.82
1.97
2.7
2.1
—
—
—
0
0
26
169
2.41
1.96
18.3
6.6
0.63
0.66
%
0.09
26
155
26
172
2.34
1.85
18.4
6.7
3.02
2.81
%
0.18
26
159
18
102
2.34
1.82
13.4
8.0
—
—
—
0
0
26
173
2.32
1.81
18.5
6.9
9.00
8.08
%
1.27
26
161
26
174
2.30
1.77
17.3
6.4
59.95
58.72
%
0.21
26
162
10
43
2.73
1.74
6.2
6.2
100.20
104.16
mmol/l
—
10
43
26
175
2.27
1.74
18.5
6.8
25.77
26.76
%
0.18
26
164
6
19
3.50
1.73
15.8
4.5
22.48
24.21
mmol/l
—
6
19
5
14
3.90
1.66
2.4
9.4
0.66
0.86
%
—
5
14
24
160
2.17
1.60
12.8
11.8
1.35
1.22
inr
0.26
11
55
17
99
2.20
1.58
11.4
3.9
0.00
0.00
estimate
—
5
37
5
15
3.63
1.57
15.0
2.4
—
—
—
0
0
32
242
2.35
1.52
8.8
4.4
—
596.83
—
0
6
17
101
2.15
1.49
2.4
2.5
—
—
—
0
0
19
118
2.11
1.49
2.3
2.9
65.37
54.42
u/l
0.66
19
108
7
29
2.69
1.46
1.1
3.5
—
—
—
0
0
13
70
2.24
1.43
12.3
3.8
—
—
—
0
0
9
44
2.33
1.37
2.2
1.3
—
—
—
0
0
15
88
2.10
1.34
2.5
2.2
2.63
2.93
mg/l
0.24
15
80
8
36
2.50
1.33
2.0
1.4
—
—
—
0
0
6
26
2.52
1.23
11.2
3.4
—
—
—
0
0
7
31
2.50
1.17
2.1
1.2
—
—
—
0
0
5
21
2.56
1.12
5.2
2.1
—
—
—
0
0
5
22
2.44
1.06
10.0
3.9
0.10
0.20
e6/l
—
5
22
16
105
1.85
1.01
1.6
1.4
—
—
—
0
0
19
138
1.69
0.83
1.7
2.0
113.10
94.51
pmol/l
—
10
69
7
38
2.01
0.78
1.0
1.6
—
—
—
0
0
7
41
1.85
0.74
4.1
4.5
1.94
1.66
%
—
7
36
30
254
1.63
0.66
4.2
3.9
—
—
—
0
0
0
23
0.00
0.60
0.0
1.3
—
6.86
—
0
18
18
138
1.53
0.59
2.1
1.9
—
—
—
0
0
35
315
1.67
0.58
46.1
18.2
15.50
14.65
%
0.35
35
307
12
84
1.60
0.57
1.9
1.9
724.67
460.07
pmol/l
0.81
12
71
6
38
1.67
0.57
14.7
3.9
—
—
—
0
0
13
94
1.55
0.54
1.5
1.6
25.25
22.14
nmol/l
0.17
13
78
5
34
1.53
0.42
1.4
1.4
—
—
—
0
0
0
18
0.00
0.41
0.0
1.1
—
127.64
—
0
5
16
129
1.39
0.38
6.5
3.1
2.30
2.34
mmol/l
0.60
16
114
11
84
1.42
0.34
1.2
1.7
3.09
2.88
g/l
—
6
46
7
51
1.45
0.34
2.3
2.3
384.86
200.63
ug/g
—
7
42
10
123
0.75
0.24
5.1
4.8
2.79
2.05
ug/l
—
10
109
5
39
1.32
0.24
1.0
1.8
—
—
—
0
0
5
41
1.25
0.23
1.6
1.4
—
—
—
0
0
12
99
1.30
0.23
6.6
3.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
5
69
0.69
0.18
1.6
3.1
2.44
2.46
mmol/l
—
5
56
6
76
0.75
0.17
3.3
2.7
1.11
0.82
ug/l
—
6
52
7
84
0.80
0.16
1.4
1.7
2.41
1.65
mg/l
—
7
69
5
47
1.07
0.10
1.0
1.4
—
336.00
—
0
10
11
122
0.87
0.08
5.6
3.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
7.1
—
9.29
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
11.3
—
40.29
—
0
7
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
6.52
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
56.83
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
7.1
—
105.71
—
0
7
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.3
—
286.83
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
8.14
—
0
7

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: N14_PROTEINURIA_AND_RENAL_GLOMERULAR_DAMAGE_FOCAL_GLOMERULONEPHRITIS – Proteinuria and renal glomerular damage; focal glomerulonephritis

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).