Panhypopituitarism

E4_PANHYPOPITUITARISM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E23.00
  • Hospital discharge: ICD-9 2532A
  • Cause of death: ICD-10 E23.00
  • Cause of death: ICD-9 2532A|2532B

2 out of 7 registries used, show all original rules.

734

4. Check minimum number of events

None

734

5. Include endpoints

None

734

6. Filter based on genotype QC (FinnGen only)

663

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 663 271 392
Unadjusted period prevalence (%) 0.15 0.10 0.18
Median age at first event (years) 54.39 48.92 58.18

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
680
Matched controls
6800
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
365.5
307.7
280
13
H03AA01
ATC
levothyroxine sodium; systemic
46.9
307.7
591
843
H02AB09
ATC
hydrocortisone; systemic
478.8
307.7
549
59
101
Kela drug reimbursment
Anterior pituitary hypofunction
1034.2
307.7
463
14
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
307.7
671
*
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
695.2
307.7
344
10
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
25.3
307.7
320
231
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
37.6
277.8
181
65
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
678.9
246.3
229
5
H53.4
ICD-10 Finland
Visual field defects
24.0
157.9
118
59
102
Kela drug reimbursment
Diabetes insipidus
624.2
155.4
148
*
XCK00
NOMESCO Finland
Perimetry
12.1
149.0
170
183
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
16.2
122.2
110
80
H01AC01
ATC
somatropin; parenteral
185.4
119.7
122
8
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
22.2
92.6
70
35
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
351.8
92.2
91
*
E23.2
ICD-10 Finland
Diabetes insipidus
494.2
89.4
87
*
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
10.5
89.0
106
118
301
Kela drug reimbursment
Growth hormone
245.6
85.5
86
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
28.7
85.1
58
22
E23.05
ICD-10 Finland
Lack of TSH
310.7
82.5
82
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.3
81.3
160
315
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
442.3
80.7
79
*
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
272.1
72.9
73
*
G02CB01
ATC
bromocriptine; systemic
22.4
69.6
52
25
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.1
63.2
236
776
D35.30
ICD-10 Finland
Craniopharyngoma
+∞
61.4
58
*
ZXC86
NOMESCO Finland
Use of endoscopic device
92.8
61.2
67
8
E23.03
ICD-10 Finland
Lack of ACTH
173.2
61.0
63
*
N04BC06
ATC
cabergoline; oral
117.5
60.0
64
6
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
20.4
56.7
44
23
121
Kela drug reimbursment
Severe hypofunction of sexual glands
13.2
56.2
55
45
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
9.0
56.1
73
90
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
17.3
56.0
47
29
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
8.9
55.6
73
91
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
571.4
54.3
53
*
E22.1
ICD-10 Finland
Hyperprolactinaemia
99.6
50.6
55
6
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
143.4
50.6
53
*
E23.0
ICD-10 Finland
Hypopituitarism
513.0
49.0
48
*
T99
ICPC
Endocr/metab/nutrit disease other
11.4
47.6
51
48
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
489.9
46.9
46
*
E89.30
ICD-10 Finland
Postprocedural hypopituitarism
+∞
45.3
43
*
E23
ICD-10 Finland
Hypofunction and other disorders of pituitary gland
466.9
44.8
44
*
2273A
ICD-9 Finland
Benign neoplasm of other endocrine glands and related structures, Pituitary gland and craniopharyngeal duct (pouch)
+∞
44.2
42
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.5
41.8
187
672
ZXC95
NOMESCO Finland
Use of surgical navigator
12.9
39.6
39
32
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
410.1
39.5
39
*
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.8
38.4
139
433
E23.08
ICD-10 Finland
Hypopituitarism
+∞
37.9
36
*
AA1AD
NOMESCO Finland
CT of head and brain
2.9
37.8
281
1342
N91.1
ICD-10 Finland
Secondary amenorrhoea
13.1
36.0
35
28
Y28
ICPC
Limited function/disability (Y)
54.4
34.8
41
8
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
60.6
34.6
40
7
H47.2
ICD-10 Finland
Optic atrophy
53.0
33.8
40
8
9350/1-C75.2
ICD-O-3
Craniopharyngioma, NOS, of craniopharyngeal duct
+∞
33.6
32
*
2532A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Panhypopituitarism[PANHYPOPITUITARISMUS]
+∞
32.6
31
*
2542
FHL
Transasal hypophysectomy
+∞
31.5
30
*
E23.6
ICD-10 Finland
Other disorders of pituitary gland
327.2
31.1
31
*
WVA30, ,
SPAT
4.4
30.6
84
213
A55
ICPC
General and Unspecified, Local injection/infiltration
10.8
30.0
33
32
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
28.4
236
1161
T28
ICPC
Limited function/disability (T)
10.8
26.4
29
28
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
38.4
26.4
33
9
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.7
26.0
180
805
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
25.8
124
455
TAB00
NOMESCO Finland
Lumbar puncture
4.5
25.0
64
153
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
7.1
24.0
37
55
2370A
ICD-9 Finland
Neoplasm of uncertain behaviour of endocrine glands and nervous system, Pituitary gland and craniopharyngeal duct
+∞
23.0
22
*
22620
ICD-8 Finland
Benign neoplasm of endocrine glands, Pituitary gland and craniopharyngeal duct (pouch)
+∞
23.0
22
*
R51.80
ICD-10 Finland
Headache
2.7
22.8
150
650
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.2
22.7
101
353
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
22.5
278
1598
D35.31
ICD-10 Finland
Cyst in Rathke's pocket
118.9
21.7
23
*
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
118.9
21.7
23
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.7
21.3
72
211
E23.06
ICD-10 Finland
Empty sella
79.4
20.8
23
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.1
20.2
313
1946
E27.2
ICD-10 Finland
Addisonian crisis
+∞
19.9
19
*
WX882
NOMESCO Finland
High dependency care
5.1
19.0
41
85
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
5.8
18.9
35
63
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
7.6
18.8
27
37
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
14.7
18.7
31
22
105
Kela drug reimbursment
Adrenal cortical hypofunction
195.2
18.6
19
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
18.5
242
1400
E03.89
ICD-10 Finland
Other specified hypothyroidism
4.9
18.5
42
91
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
18.4
161
790
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
5.9
18.2
33
58
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.8
18.2
98
380
E23.7
ICD-10 Finland
Disorder of pituitary gland, unspecified
+∞
17.8
17
*
CS494
NOMESCO Finland
Other visual field testing
5.6
17.8
34
63
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
17.7
223
1268
R50.9
ICD-10 Finland
Fever, unspecified
2.4
17.7
143
677
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
17.4
124
554
G03FB08
ATC
dydrogesterone and estrogen; systemic
4.3
17.3
46
113
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.8
17.0
97
387
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
6.1
16.6
29
49
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
92.4
16.6
18
*
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
23.7
16.5
23
10
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
12.6
16.5
29
24
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
13.2
16.3
28
22
H02AA02
ATC
fludrocortisone; oral
17.2
16.2
25
15
N03AX14
ATC
levetiracetam; systemic
4.9
15.8
35
74
G02CB03
ATC
cabergoline; oral
34.3
15.8
20
6
25310
ICD-8 Finland
Diseases of pituitary gland, Panhypopituitarismus
+∞
15.7
15
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.5
15.6
111
494
Z3231
NOMESCO Finland
Registered nurse
2.0
15.4
219
1292
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
29.4
15.3
20
7
ZXA10
NOMESCO Finland
Bilateral
2.2
15.2
146
740
AA1BD
NOMESCO Finland
Extensive CT of head and brain
5.3
15.2
31
61
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
14.8
146
747
-50
ICPC
Medication/prescr/renewal
3.8
14.7
47
132
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
5.3
14.7
30
59
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
14.3
354
2495
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
4.1
14.1
39
99
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
54.5
13.9
16
*
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
12.4
13.7
24
20
D35.3
ICD-10 Finland
Benign neoplasm: Craniopharyngeal duct
+∞
13.6
13
*
25320
ICD-8 Finland
Diseases of pituitary gland, Chromophobe adenoma, pituitary
+∞
13.6
13
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
13.5
77
307
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
13.2
203
1220
ZXD05
NOMESCO Finland
Urgent procedure
1.9
13.1
219
1351
E66.8
ICD-10 Finland
Other obesity
3.4
13.1
49
153
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
13.1
151
819
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.0
13.1
61
218
T73
ICPC
Neoplasm endocrine other/unspecified
71.2
12.6
14
*
A50
ICPC
General and Unspecified, Medication/prescr/renewal
3.6
12.6
42
122
E23.3
ICD-10 Finland
Hypothalamic dysfunction, not elsewhere classified
+∞
12.5
12
*
N75
ICPC
Benign neoplasm nervous system
+∞
12.5
12
*
G03GA01
ATC
chorionic gonadotrophin; parenteral
5.2
12.5
26
52
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.1
12.4
53
180
XA800
NOMESCO Finland
Neuropsychological investigation
3.3
12.0
47
151
104
Kela drug reimbursment
Thyroid insufficiency
3.0
12.0
54
189
E87.0
ICD-10 Finland
Hyperosmolality and hypernatraemia
19.3
11.6
17
9
2530A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Acromegaly and gigantism[ACROMEGALIA]
+∞
11.5
11
*
E89.39
ICD-10 Finland
Postprocedural hypopituitarism, other or several procedures
+∞
11.5
11
*
H53.2
ICD-10 Finland
Diplopia
3.7
11.5
36
100
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.3
11.3
89
412
T29
ICPC
Endocr/metab/nutr sympt/compl other
5.0
11.3
24
49
G03FB06
ATC
medroxyprogesterone and estrogen; systemic
3.1
11.2
47
158
SPAT1254
SPAT
Administration of medicine
2.1
11.1
116
604
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
44.1
10.9
13
*
R53
ICD-10 Finland
Malaise and fatigue
1.9
10.9
190
1178
R11
ICD-10 Finland
Nausea and vomiting
2.4
10.8
78
348
A41.9
ICD-10 Finland
Sepsis, unspecified
3.4
10.7
39
120
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
5.1
10.6
22
44
G03DB01
ATC
dydrogesterone; oral
2.5
10.5
70
300
D35.9
ICD-10 Finland
Benign neoplasm: Endocrine gland, unspecified
+∞
10.4
10
*
E23.1
ICD-10 Finland
Drug-induced hypopituitarism
+∞
10.4
10
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
10.8
10.3
19
18
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.0
10.3
22
45
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
19.1
10.3
15
8
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
10.3
69
297
G03GA02
ATC
human menopausal gonadotrophin; parenteral
5.4
10.2
20
38
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.9
10.0
47
169
Z2446
NOMESCO Finland
Social worker
2.6
9.7
60
248
N29
ICPC
Neurological sympt/complt other
5.1
9.6
20
40
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
101.4
9.4
10
*
E22.9
ICD-10 Finland
Hyperfunction of pituitary gland, unspecified
+∞
9.4
9
*
H47.4
ICD-10 Finland
Disorders of optic chiasm
+∞
9.4
9
*
9350/1-C75.1
ICD-O-3
Craniopharyngioma, NOS, of pituitary gland
+∞
9.4
9
*
E22.80
ICD-10 Finland
Central precocious puberty
+∞
9.4
9
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.1
9.3
40
136
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
9.3
74
344
R55
ICD-10 Finland
Syncope and collapse
2.2
9.2
87
434
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
9.1
245
1705
ZX114
NOMESCO Finland
Intramuscular
4.9
9.1
20
42
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
10.2
9.1
17
17
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
37.2
9.0
11
*
D33.2
ICD-10 Finland
Benign neoplasm: Brain, unspecified
37.2
9.0
11
*
2152
FHL
Extraction, big brain
37.2
9.0
11
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.3
9.0
72
335
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
18.9
9.0
13
7
WX402
NOMESCO Finland
General anaesthesia
1.8
8.7
157
975
WF099
NOMESCO Finland
Other radiotherapy
11.8
8.6
15
13
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
8.6
103
561
XX1ZW
NOMESCO Finland
Very extensive written report from radiologist
16.5
8.6
13
8
E28.3
ICD-10 Finland
Primary ovarian failure
20.3
8.5
12
6
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
8.5
154
959
E89.6
ICD-10 Finland
Postprocedural adrenocortical(-medullary) hypofunction
91.1
8.4
9
*
S50
ICPC
Skin, Medication/prescr/renewal
13.0
8.4
14
11
E2300, D352,
ICD-10 Finland
+∞
8.3
8
*
C75.1
ICD-10 Finland
Malignant neoplasm: Pituitary gland
+∞
8.3
8
*
UDM02
NOMESCO Finland
Sinoscopy
3.8
8.2
25
68
A02BC02
ATC
pantoprazole; systemic
1.6
8.2
447
3673
Z2445
NOMESCO Finland
Psychologist
2.9
8.0
38
137
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
22.3
8.0
11
5
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.4
8.0
28
84
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.6
7.8
47
192
R51
ICD-10 Finland
Headache
2.6
7.7
43
169
2151
FHL
Resection, big brain
45.5
7.7
9
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
7.7
83
435
R5140
NOMESCO Finland
Monitoring the use of the aid
2.0
7.7
90
486
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
7.7
99
553
D35.1
ICD-10 Finland
Benign neoplasm: Parathyroid gland
18.6
7.6
11
6
G47.3
ICD-10 Finland
Sleep apnoea
1.7
7.6
169
1110
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
12.0
7.6
13
11
Y99
ICPC
Genital disease male other
12.0
7.6
13
11
N76
ICPC
Neoplasm nervous system unspecified
25.3
7.6
10
*
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
10.2
7.6
14
14
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.5
7.5
25
73
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
7.4
31
104
2159
FHL
Other measure in this category
80.9
7.4
8
*
N04BC01
ATC
bromocriptine; oral
80.9
7.4
8
*
W11
ICPC
Contraception oral
0.1
7.3
*
263
N97.0
ICD-10 Finland
Female infertility associated with anovulation
6.9
7.3
17
25
25300
ICD-8 Finland
Diseases of pituitary gland, Aeromegalia
+∞
7.3
7
*
E89.31
ICD-10 Finland
Postirradiation hypopituitarism
+∞
7.3
7
*
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.9
7.2
34
123
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
12.2
7.1
12
10
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
7.1
75
391
L28
ICPC
Limited function/disability (L)
1.8
7.0
121
739
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.6
7.0
39
154
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
6.4
7.0
17
27
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
7.0
92
517
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.8
7.0
34
125
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.8
7.0
21
57
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.1
6.8
28
93
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
6.8
79
425
N28
ICPC
Limited function/disability (N)
4.3
6.8
17
40
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.1
6.7
62
306
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
22.8
6.7
9
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
6.7
93
532
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
6.5
6.7
16
25
E34.35
ICD-10 Finland
Abnormal growth retardation
12.4
6.6
11
9
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
6.6
241
1779
WF002
NOMESCO Finland
Radical radiotherapy
2.4
6.5
46
203
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.7
6.5
20
55
SPAT1262
SPAT
Handing over of treatment supplies
1.8
6.5
114
700
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.7
6.5
35
136
AA4AD
NOMESCO Finland
CT of sella turcica
70.5
6.4
7
*
2535A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Diabetes insipidus
70.5
6.4
7
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
6.3
247
1847
G91.1
ICD-10 Finland
Obstructive hydrocephalus
9.4
6.3
12
13
G44.2
ICD-10 Finland
Tension-type headache
1.8
6.3
90
519
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
6.3
470
4022
AAK40
NOMESCO Finland
Closure of cerebrospinal fluid fistula
18.2
6.3
9
5
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
18.2
6.3
9
5
25319
ICD-8 Finland
Diseases of pituitary gland, Hypopituitarismus alia sive NUD
+∞
6.3
6
*
Y55
ICPC
Male Genital, Local injection/infiltration
+∞
6.3
6
*
D35.50
ICD-10 Finland
Carotid body
+∞
6.3
6
*
E89.3
ICD-10 Finland
Postprocedural hypopituitarism
+∞
6.3
6
*
D33.05
ICD-10 Finland
Other lateral benign tumor in temporal lobe
+∞
6.3
6
*
D44.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Craniopharyngeal duct
+∞
6.3
6
*
G02CB04
ATC
quinagolide; oral
+∞
6.3
6
*
D352, E2300,
ICD-10 Finland
+∞
6.3
6
*
E23.02
ICD-10 Finland
Neurosecretory dysfunction of the growth hormone
26.9
6.2
8
*
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
3.7
6.2
19
52
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
6.2
106
645
R06.0
ICD-10 Finland
Dyspnoea
1.6
6.2
181
1267
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
2.9
6.2
28
99
SPAT1301
SPAT
No procedures
1.6
6.1
198
1420
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
6.1
101
610
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
10.1
6.0
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
493
603
27.09
307.65
7.1
1.9
241.76
380.74
nmol/l
12.63
463
561
333
56
115.57
307.65
4.4
2.0
13.37
24.29
nmol/l
8.17
325
50
360
204
36.38
307.65
4.9
1.5
396.74
267.66
mu/l
4.72
350
190
138
16
107.96
267.34
3.0
2.1
0.74
1.00
ug/l
0.28
131
16
171
64
35.36
258.38
2.3
1.3
42.34
28.67
ng/l
0.55
165
64
216
214
14.33
203.34
2.4
1.5
4.93
9.04
u/l
3.27
144
168
337
707
8.47
172.27
7.3
2.3
13.62
13.54
nmol/l
0.06
316
646
232
328
10.22
166.94
3.4
3.7
4.09
4.61
pmol/l
7.71
218
294
113
72
18.62
134.82
2.6
1.3
287.80
278.06
mosm/kgh2o
1.63
101
52
169
236
9.20
120.40
2.3
1.5
9.55
21.76
iu/l
6.39
120
196
93
61
17.50
108.79
4.6
1.3
389.43
259.80
mu/l
1.72
87
46
87
109
9.01
66.28
2.2
1.3
78.12
64.46
mmol/l
1.41
81
99
115
210
6.39
62.32
3.7
1.9
189.50
222.06
pmol/l
1.43
103
198
73
88
9.17
57.15
2.5
1.5
0.25
0.29
nmol/l
0.34
47
68
58
6
105.53
53.74
1.9
1.0
—
—
—
0
0
494
2972
3.42
46.22
11.4
8.1
1.20
1.21
mmol/l
0.87
416
2598
622
4373
5.95
45.63
11.6
4.0
15.29
14.78
pmol/l
4.92
613
3997
352
1764
3.06
45.10
4.9
4.3
7.39
7.40
ph
0.12
263
1272
268
1173
3.12
43.32
3.5
3.0
498.78
554.80
mosm/kgh2o
3.57
240
1025
454
2663
3.12
43.08
10.8
7.4
1.20
1.21
mmol/l
1.63
436
2477
70
132
5.80
36.16
1.9
1.6
786.97
1002.24
e6/l
0.09
62
101
68
129
5.75
34.88
1.9
1.6
39.24
47.91
e6/l
0.07
59
94
61
113
5.83
32.04
2.0
1.6
—
—
—
0
0
128
444
3.32
29.51
5.5
3.8
1.22
1.22
mmol/l
0.39
120
384
61
129
5.10
27.66
1.3
1.5
3.69
3.73
mmol/l
0.09
56
121
504
3554
2.62
26.78
8.8
5.6
6.38
6.74
mmol/l
4.10
492
3386
303
1721
2.37
26.12
5.8
4.6
—
—
—
0
0
38
54
7.39
25.68
2.4
1.9
—
—
—
0
0
169
740
2.71
25.38
11.6
9.7
7.41
7.41
ph
0.07
109
429
167
729
2.71
25.22
11.7
9.8
0.58
0.80
mmol/l
0.38
130
600
167
744
2.65
24.11
11.7
9.6
5.00
5.06
kpa
0.50
156
718
167
745
2.65
24.04
11.7
9.6
13.74
12.18
kpa
2.93
156
721
389
2529
2.26
23.53
3.8
2.5
77.95
74.99
nmol/l
1.44
368
2280
53
114
4.96
23.52
1.9
1.8
0.66
0.84
g/l
0.55
28
96
392
2563
2.25
23.29
5.8
5.5
35.06
35.75
g/l
1.59
376
2423
122
487
2.83
21.63
1.4
1.4
—
—
—
0
0
199
1030
2.32
20.34
4.4
3.9
0.84
0.82
mmol/l
2.27
189
984
53
130
4.34
20.00
3.2
3.6
—
—
—
0
0
310
1961
2.07
18.70
3.7
3.5
38.89
86.62
e6/l
0.70
252
1507
34
60
5.91
18.69
1.9
1.3
—
—
—
0
0
33
59
5.83
17.89
1.9
1.3
5.16
7.37
g/l
2.75
13
47
33
59
5.83
17.89
1.9
1.3
0.36
0.41
g/l
0.17
13
46
33
59
5.83
17.89
1.9
1.3
2.77
2.86
g/l
0.09
13
47
274
1681
2.06
17.74
3.7
3.4
0.50
0.45
e6/l
0.11
216
1233
431
3132
2.03
17.04
7.7
7.3
11.63
11.98
umol/l
0.16
417
2997
290
1836
2.01
17.03
2.8
2.2
229.34
308.31
u/l
0.67
273
1749
114
499
2.54
16.62
3.9
5.1
0.09
0.11
%
0.16
44
142
97
395
2.70
16.35
9.9
12.3
24.11
24.32
mmol/l
0.39
97
389
230
1363
2.04
16.05
3.0
2.8
4.42
4.67
e6/l
0.16
218
1242
162
847
2.20
15.67
6.2
6.7
0.99
1.04
mmol/l
1.68
155
788
378
2685
1.92
15.26
17.5
11.7
0.00
0.00
e9/l
0.40
321
2197
110
493
2.47
15.18
3.3
2.5
10.02
10.96
g/l
1.72
94
457
167
894
2.15
15.17
2.4
2.6
24.61
23.01
%
0.81
161
842
113
513
2.44
15.17
3.9
5.4
0.02
0.15
%
1.02
43
133
112
508
2.44
15.06
3.8
4.8
0.62
0.61
%
0.03
45
162
253
1583
1.95
14.90
2.4
2.3
2.86
2.91
mg/l
0.15
230
1382
145
741
2.22
14.77
2.2
2.8
1.86
1.78
%
0.37
126
679
307
2054
1.90
14.73
7.3
6.5
—
—
—
0
0
128
623
2.30
14.65
14.1
10.3
125.53
122.29
g/l
1.02
120
611
14
0
+∞
14.63
5.6
0.0
1.60
—
mu/l
—
14
0
325
2221
1.89
14.55
4.3
4.1
28.40
101.22
e6/l
2.74
257
1575
114
530
2.38
14.48
3.9
5.0
1.04
0.88
%
0.34
45
175
43
115
3.92
14.45
3.6
4.4
2.48
2.62
mmol/l
0.14
31
81
31
64
5.03
14.39
2.6
2.0
—
—
—
0
0
135
679
2.23
14.26
13.6
10.1
95.96
95.42
%
0.36
127
660
102
454
2.47
14.25
4.8
3.7
—
—
—
0
0
31
67
4.80
13.65
1.8
1.3
—
—
nmol/l
—
0
0
239
1505
1.91
13.55
4.6
4.4
89.97
88.64
%
0.36
233
1485
541
4425
2.09
13.47
11.1
8.7
79.95
79.88
u/l
0.01
535
4217
181
1040
2.01
13.41
2.5
2.7
13.20
13.16
umol/l
0.02
171
976
171
972
2.01
13.01
2.5
2.6
2.24
2.31
g/l
0.73
161
905
116
569
2.25
12.94
9.7
10.7
—
—
—
0
0
99
457
2.37
12.71
5.5
3.9
7.42
7.42
ph
0.29
88
385
378
2787
1.80
12.57
12.0
15.1
1.17
1.26
inr
3.07
337
2328
116
576
2.22
12.54
2.4
2.8
77.10
68.71
e9/l
1.24
78
425
374
2786
1.76
11.66
3.3
3.0
151.76
137.59
ug/l
0.65
359
2614
603
5229
2.35
11.65
8.8
5.0
0.93
1.92
mu/l
68.48
526
4843
410
3147
1.76
11.40
7.7
6.6
1.99
1.94
e9/l
0.36
366
2794
467
3737
1.80
11.09
5.4
4.5
3503.56
1285.26
e6/l
—
9
62
436
3423
1.76
11.03
10.7
10.0
4.50
4.13
e9/l
2.09
391
2998
127
685
2.05
11.01
5.1
4.2
7.37
7.38
ph
0.49
83
399
377
2855
1.72
10.72
8.0
6.7
8.37
8.99
%
4.86
364
2700
376
2846
1.72
10.71
8.0
6.6
2.85
2.91
%
0.18
364
2685
319
2310
1.72
10.67
4.8
3.9
27.39
43.33
ng/l
2.24
246
1668
401
3095
1.72
10.58
7.7
6.5
0.57
0.59
e9/l
1.06
353
2679
401
3099
1.72
10.49
7.6
6.5
0.04
0.04
e9/l
0.10
354
2683
273
1903
1.73
10.43
3.6
2.8
53.81
103.96
u/l
0.64
256
1786
374
2841
1.70
10.38
8.1
6.7
0.65
0.67
%
0.28
363
2678
28
70
4.13
10.32
1.8
1.3
0.18
0.19
nmol/l
0.04
23
51
381
2912
1.70
10.31
8.0
6.7
29.31
27.41
%
2.19
369
2783
407
3191
1.69
9.79
8.0
6.7
0.19
0.20
e9/l
0.51
358
2810
19
36
5.40
9.68
1.2
1.1
31.54
39.70
mg/l
0.60
14
28
33
98
3.49
9.56
3.7
3.3
4.13
4.54
e9/l
0.44
33
98
81
390
2.22
9.36
15.3
7.4
24.05
24.14
mmol/l
0.10
73
373
118
659
1.96
9.19
4.8
4.3
2.28
1.86
mmol/l
0.80
99
559
636
5766
2.59
9.05
37.5
19.8
139.90
139.64
mmol/l
1.53
636
5662
636
5773
2.57
8.89
36.8
20.0
3.89
3.98
mmol/l
18.27
636
5663
368
2864
1.62
8.66
7.6
6.6
55.77
57.40
%
1.48
361
2753
245
1726
1.66
8.61
4.8
3.8
0.00
0.01
estimate
0.96
120
593
68
317
2.27
8.48
1.4
1.2
—
—
—
0
0
59
259
2.40
8.44
2.7
1.9
4.49
2.70
ug/l
0.47
53
233
266
1927
1.62
8.29
2.7
2.5
—
—
—
0
0
598
5327
2.02
8.27
7.8
6.5
39.73
39.54
mmol/mol
0.18
579
5015
24
64
3.85
8.13
3.1
4.3
—
—
—
0
0
76
379
2.13
8.03
12.6
5.6
—
—
—
0
0
324
2492
1.57
7.68
6.8
5.4
1.67
2.46
ug/l
3.19
301
2243
102
584
1.88
7.31
10.6
9.8
1.49
1.38
mmol/l
0.30
102
573
388
3140
1.55
7.13
4.4
3.8
0.00
0.51
estimate
0.51
123
600
271
2039
1.55
6.86
3.4
3.5
44.72
33.90
u/l
0.62
260
1939
384
3121
1.53
6.77
4.6
3.8
0.00
8.04
estimate
1.08
128
653
601
5446
1.89
6.67
6.2
5.1
5.62
5.98
mmol/l
14.03
584
5010
466
3964
1.56
6.56
5.5
4.4
—
2.23
—
0
7
98
577
1.82
6.41
2.6
2.6
0.21
0.21
g/l
0.42
93
533
35
137
2.64
6.38
4.0
3.1
56.74
58.31
%
0.27
35
137
48
219
2.28
6.32
1.2
1.3
—
—
—
0
0
203
1454
1.56
6.29
2.5
2.6
—
—
—
0
0
9
5
18.21
6.27
1.1
1.0
—
—
titre
—
0
0
377
3090
1.49
6.12
4.6
3.7
0.00
0.00
estimate
-0.00
127
642
259
1983
1.49
5.80
4.8
3.7
2.33
2.35
mmol/l
2.15
247
1813
190
1364
1.55
5.76
5.5
4.9
—
—
—
0
0
16
31
5.26
5.73
1.6
1.2
0.44
0.49
ratio
—
7
18
300
2372
1.47
5.69
4.6
3.6
0.01
0.01
estimate
0.07
111
535
24
82
3.00
5.62
2.2
2.8
—
—
—
0
0
62
330
1.97
5.52
6.6
4.2
—
—
—
0
0
220
1644
1.50
5.49
3.5
3.2
—
—
—
0
0
31
125
2.55
5.36
1.3
1.6
—
—
—
0
0
614
5675
1.84
5.36
26.3
16.6
25.17
24.99
mg/l
0.05
563
4680
46
223
2.14
5.26
1.3
1.2
0.29
1.93
u/ml
—
7
15
70
397
1.85
5.16
2.1
2.8
—
—
—
0
0
28
111
2.59
5.02
3.9
3.5
6.80
9.56
pmol/l
1.36
28
111
22
77
2.92
4.96
1.6
1.9
33.77
32.86
pg
0.44
22
77
165
1184
1.52
4.92
1.9
1.8
442.19
21638439.96
pmol/l
0.94
139
989
111
727
1.63
4.92
2.6
1.8
—
—
—
0
0
225
1722
1.46
4.87
4.1
3.2
0.00
0.05
estimate
0.55
103
510
141
985
1.54
4.75
3.4
3.1
2.49
1.72
e6/l
0.61
70
497
25
571
0.42
4.69
1.3
1.4
—
—
—
0
0
16
48
3.39
4.63
1.3
1.2
121.94
98.96
pmol/l
0.64
16
48
7
5
14.12
4.58
2.0
1.0
—
—
—
0
0
333
2766
1.40
4.47
3.1
2.9
—
—
estimate
—
0
0
11
19
5.86
4.45
3.9
1.3
309.64
70.58
nmol/24h
0.79
11
19
113
762
1.58
4.43
1.3
1.3
—
—
—
0
0
624
5851
1.81
4.41
25.3
14.5
—
—
—
0
0
297
2429
1.40
4.32
2.2
2.0
1.59
1.37
mmol/l
3.94
265
2065
186
1404
1.45
4.25
1.5
1.3
0.76
1.57
u/ml
1.65
55
381
54
303
1.85
4.14
15.2
6.1
1.54
1.56
%
0.04
49
286
37
182
2.09
4.12
1.3
1.3
112.00
80.00
titre
—
5
18
636
6015
1.89
4.11
36.2
21.4
84.07
80.20
umol/l
3.07
636
5955
116
800
1.54
4.11
1.5
1.4
372.80
456.30
titre
0.33
25
184
48
262
1.90
4.01
7.5
4.6
25.46
24.81
mmol/l
1.08
48
250
269
2191
1.38
3.91
2.4
2.1
—
—
—
0
0
229
1818
1.39
3.88
3.2
3.4
1683.06
1376.69
ng/l
0.35
197
1560
145
1060
1.47
3.88
3.2
3.0
0.73
0.94
e6/l
0.55
75
569
6
221
0.27
3.84
1.2
1.1
1.47
1.52
g/l
—
6
221
133
958
1.48
3.83
2.0
1.7
1289.62
1165.23
nmol/l
0.84
104
730
15
49
3.11
3.82
2.5
1.8
41.59
38.10
%
0.32
15
49
20
449
0.43
3.62
1.4
1.8
3.30
3.48
mmol/l
0.45
12
332
571
5293
1.49
3.59
5.2
4.3
1.58
1.31
mmol/l
5.91
545
4902
48
273
1.82
3.56
16.3
6.5
0.80
0.85
%
0.51
43
255
16
57
2.85
3.54
1.3
1.1
—
—
—
0
0
34
173
2.02
3.50
8.3
9.7
—
—
—
0
0
49
284
1.78
3.42
1.4
2.0
1.40
1.45
g/l
0.13
43
259
12
32
3.80
3.40
2.1
2.5
502.57
502.60
min
—
7
20
306
2585
1.33
3.37
2.3
2.1
99.39
94.56
pmol/l
1.00
178
1384
219
1760
1.36
3.36
8.0
6.5
—
—
—
0
0
101
711
1.49
3.25
2.5
3.1
6.51
8.25
umol/l
0.96
90
642
163
1258
1.39
3.20
1.5
1.4
2.23
2.48
g/l
1.20
112
779
296
2509
1.32
3.12
3.8
3.4
6.17
6.19
ph
0.10
174
1439
8
231
0.34
3.10
1.3
1.1
0.89
0.89
g/l
—
8
231
5
5
10.06
2.98
1.0
1.0
—
—
—
0
0
5
5
10.06
2.98
1.2
1.0
5.18
7.59
mg/g
—
5
5
5
5
10.06
2.98
1.2
1.0
—
—
—
0
0
13
46
2.86
2.93
2.5
3.1
8.31
8.51
mmol/l
0.06
13
46
24
115
2.13
2.92
1.0
1.1
—
—
—
0
0
19
83
2.33
2.86
1.1
1.3
—
—
—
0
0
21
96
2.23
2.86
1.5
1.3
9.56
6.02
u/ml
—
9
47
146
1129
1.37
2.81
3.7
3.1
2.44
2.45
mmol/l
0.22
133
1021
15
59
2.58
2.80
2.8
2.8
—
—
—
0
0
18
80
2.28
2.62
2.5
2.4
0.47
1.46
g/24h
—
8
49
19
87
2.22
2.59
2.1
2.0
1.16
0.94
%
—
10
62
12
44
2.76
2.55
2.2
2.3
521.43
644.52
ml
—
7
25
12
44
2.76
2.55
1.5
1.5
37.51
184.88
pmol/l
10.64
12
44
5
7
7.19
2.55
1.6
1.3
—
—
—
0
0
22
108
2.07
2.54
1.1
1.1
1.56
93.70
iu/ml
—
9
21
32
180
1.82
2.52
22.4
8.6
1.27
1.29
mmol/l
0.05
23
159
7
16
4.41
2.48
3.4
1.6
28.00
36.13
%
—
7
16
64
435
1.52
2.46
3.8
4.5
77.97
86.82
ng/l
0.41
57
392
6
12
5.03
2.40
1.0
1.2
—
—
—
0
0
28
154
1.85
2.37
1.7
2.0
223.38
4.58
iu/l
0.47
14
63
144
1140
1.33
2.37
3.6
4.1
188.75
466.55
ng/l
1.50
103
895
587
5568
1.40
2.35
6.3
5.1
4.46
4.55
mmol/l
1.38
570
5222
594
5652
1.40
2.27
6.8
5.8
2.65
2.67
mmol/l
0.22
578
5269
584
5543
1.38
2.25
6.2
5.0
1.30
1.41
mmol/l
10.56
565
5160
181
1491
1.29
2.23
4.1
3.1
0.60
0.75
ug/l
3.71
143
930
11
41
2.71
2.21
1.2
1.3
—
—
—
0
0
206
1732
1.27
2.15
2.0
1.7
18.64
20.09
nmol/l
0.80
186
1472
164
1340
1.30
2.14
1.9
1.9
1.46
1.38
mg/l
0.07
122
1041
39
246
1.62
2.09
2.6
2.7
21.53
21.10
s
0.25
34
233
18
89
2.05
2.07
1.3
1.6
—
—
—
0
0
18
89
2.05
2.07
1.3
1.6
—
—
—
0
0
18
89
2.05
2.07
1.3
1.6
—
—
—
0
0
18
89
2.05
2.07
1.3
1.6
—
—
—
0
0
40
256
1.60
2.03
2.0
2.0
1.94
8.08
iu/ml
—
5
65
10
38
2.66
2.01
1.0
1.1
—
—
—
0
0
30
181
1.69
1.91
1.3
1.4
290.19
286.00
ug/g
0.03
15
110
12
52
2.33
1.88
2.1
3.1
311.17
1157.02
mg
2.81
12
52
639
6199
1.51
1.81
40.1
24.8
249.18
246.46
e9/l
0.50
634
6089
33
208
1.62
1.80
3.5
4.2
38.98
43.98
mg/l
0.11
28
179
639
6201
1.51
1.78
40.1
24.7
90.51
90.98
fl
1.86
639
6142
639
6203
1.50
1.76
40.2
24.8
4.57
4.54
e12/l
0.83
634
6076
639
6203
1.50
1.76
40.0
24.7
30.15
30.36
pg
2.22
639
6143
639
6203
1.50
1.76
41.3
25.5
40.94
40.72
%
0.56
639
6138
639
6204
1.50
1.74
40.3
24.8
7.24
6.79
e9/l
5.81
634
6074
9
36
2.52
1.74
2.2
1.7
89.33
79.56
umol/l
—
9
36
8
30
2.69
1.73
1.4
1.2
146.13
182.12
mmol/24h
—
8
30
7
24
2.94
1.72
4.9
1.4
0.00
0.13
estimate
—
7
24
30
187
1.63
1.72
3.5
4.0
1.66
2.47
ratio
0.61
16
110
24
141
1.73
1.70
1.4
1.4
—
—
—
0
0
51
361
1.45
1.67
1.3
1.2
71.35
138.57
u/ml
1.01
21
150
96
756
1.31
1.65
1.4
1.3
—
—
—
0
0
70
526
1.37
1.64
4.9
4.7
7.33
7.35
ph
0.20
63
385
64
474
1.39
1.64
1.4
1.5
—
—
—
0
0
112
902
1.29
1.63
2.7
2.2
—
—
—
0
0
15
271
0.54
1.56
1.5
1.6
—
—
—
0
0
8
33
2.44
1.54
1.5
1.6
—
—
—
0
0
96
764
1.30
1.54
1.7
1.5
—
—
—
0
0
96
765
1.30
1.52
4.5
3.2
4.37
5.36
e9/l
0.69
86
676
10
45
2.24
1.47
2.5
3.3
14.67
16.70
%
—
10
45
9
38
2.39
1.46
1.1
1.4
7.02
8.81
u/l
—
9
30
7
28
2.52
1.45
1.0
1.1
—
—
—
0
0
74
573
1.33
1.45
2.7
2.5
35.66
41.16
u/l
0.24
64
479
14
74
1.91
1.40
2.6
2.3
—
—
—
0
0
18
105
1.73
1.34
1.1
1.1
—
—
—
0
0
236
2105
1.19
1.31
3.3
3.5
7.83
8.12
mmol/l
0.43
210
1806
50
662
0.74
1.29
1.2
1.5
—
—
—
0
0
25
163
1.55
1.24
4.1
3.2
2.29
2.13
index
0.06
14
101
6
25
2.41
1.24
1.0
1.2
93.67
180.13
iu/ml
—
6
25
16
93
1.74
1.22
2.7
2.6
—
—
—
0
0
13
71
1.85
1.20
1.6
1.2
—
—
—
0
0
6
26
2.32
1.19
3.0
2.4
—
—
—
0
0
8
39
2.06
1.15
1.4
1.4
7.44
7.36
ph
—
8
27
57
443
1.31
1.12
3.4
3.1
135.12
203.50
ng/l
0.93
50
403
10
51
1.98
1.11
1.0
1.1
335.70
282.00
mg/l
—
10
46
39
286
1.39
1.11
2.2
2.3
—
—
—
0
0
24
160
1.52
1.10
1.1
1.2
—
—
—
0
0
7
31
2.27
1.10
1.0
1.5
31.29
28.00
umol/l
—
7
26
7
31
2.27
1.10
1.3
1.3
124.71
139.40
nmol/l
—
7
31
19
120
1.60
1.09
2.9
3.8
22.07
28.50
mg/l
0.65
13
84
161
1413
1.18
1.07
4.3
3.8
1.02
1.02
kg/l
0.09
116
945
68
546
1.27
1.06
2.6
2.2
0.14
0.03
estimate
0.37
21
117
9
49
1.85
0.99
1.6
1.2
—
—
—
0
0
20
132
1.53
0.98
1.5
1.4
120.29
154.55
au/ml
—
7
39
17
108
1.59
0.97
1.5
1.8
—
—
—
0
0
8
143
0.55
0.94
1.6
1.7
—
—
—
0
0
6
27
2.23
0.93
1.5
3.6
26.50
35.13
umol/l
—
6
19
21
142
1.49
0.93
1.3
1.2
—
—
—
0
0
214
1941
1.15
0.93
3.3
3.6
34.09
56.42
mg/l
1.45
135
1313
6
28
2.15
0.91
1.0
1.5
2.16
1.88
umol/l
—
6
22
12
71
1.70
0.89
1.2
1.1
1.91
1.64
nmol/l
0.35
12
64
17
111
1.55
0.88
1.1
1.1
—
—
—
0
0
17
112
1.53
0.85
1.1
1.1
—
—
—
0
0
129
1135
1.17
0.84
1.6
2.0
—
—
—
0
0
6
113
0.53
0.83
1.7
1.3
—
—
—
0
0
12
73
1.66
0.82
1.1
1.1
—
—
—
0
0
10
58
1.73
0.80
1.0
1.1
—
—
—
0
0
89
765
1.19
0.77
2.0
2.6
140.72
123.10
ug/g
0.15
73
611
21
150
1.41
0.74
4.4
4.8
—
—
—
0
0
47
576
0.80
0.74
1.4
1.8
—
—
—
0
0
10
60
1.68
0.72
1.2
1.1
—
—
—
0
0
30
229
1.32
0.72
1.3
1.3
—
—
—
0
0
24
177
1.37
0.71
1.2
1.2
—
—
—
0
0
419
4011
1.12
0.71
4.5
3.6
64.23
51.05
u/l
2.09
400
3806
5
26
1.93
0.70
1.4
1.0
916.80
1551.50
miu/ml
—
5
26
60
502
1.21
0.70
3.7
2.5
3.94
7.06
ug/l
2.48
52
454
22
161
1.38
0.69
2.9
2.4
36.23
106.92
ug/min
1.22
13
93
52
624
0.82
0.68
1.6
1.5
—
—
—
0
0
16
224
0.71
0.65
1.1
1.1
—
—
—
0
0
85
744
1.16
0.62
1.5
1.6
—
—
—
0
0
5
30
1.67
0.61
4.2
1.8
—
—
—
0
0
214
1990
1.11
0.61
4.3
4.3
5.22
9.40
mg/mmol
1.29
128
1309
58
492
1.20
0.61
1.3
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
4.1
—
5.80
—
0
21
20
152
1.33
0.52
1.0
1.1
—
—
—
0
0
11
75
1.47
0.51
1.5
1.3
—
—
—
0
0
55
634
0.86
0.49
1.2
1.6
—
—
—
0
0
7
106
0.66
0.49
2.1
1.4
—
—
—
0
0
115
1050
1.11
0.47
1.3
1.3
23.13
32.43
iu/ml
0.94
26
320
16
120
1.34
0.46
1.0
1.2
12.17
31.82
u/l
1.08
16
106
5
84
0.59
0.45
1.4
1.2
—
—
—
0
0
106
967
1.11
0.44
1.2
1.3
2.87
11.85
u/ml
2.77
40
383
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
7.53
—
0
5
0
16
0.00
0.41
0.0
1.1
—
26.77
—
0
16
8
59
1.36
0.41
2.3
2.2
—
—
—
0
0
16
123
1.31
0.40
1.8
2.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.9
—
36.35
—
0
17
0
18
0.00
0.40
0.0
1.0
—
10.53
—
0
12
239
2276
1.08
0.40
4.2
3.2
—
—
—
0
0
8
61
1.32
0.39
1.1
1.0
—
—
—
0
0
9
66
1.37
0.38
1.3
1.5
6.11
6.58
mmol/l
—
9
61
8
113
0.70
0.37
1.5
1.6
—
—
—
0
0
9
70
1.29
0.36
1.1
1.2
—
—
—
0
0
5
77
0.65
0.36
13.2
3.5
45.20
28.53
u/ml
—
5
77
25
297
0.84
0.34
1.0
1.1
—
—
—
0
0
6
44
1.37
0.34
4.7
4.0
0.50
0.86
index
—
6
44
29
247
1.18
0.33
2.8
2.8
—
—
—
0
0
34
297
1.15
0.30
1.7
1.6
0.34
0.33
mg/l
0.03
12
138
29
254
1.15
0.25
1.1
1.2
—
—
—
0
0
50
455
1.11
0.25
2.6
2.5
6.09
6.07
ph
0.05
33
310
9
75
1.20
0.25
2.2
2.4
—
59.76
—
0
7
41
371
1.11
0.23
1.2
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
3.3
—
1.10
—
0
10
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
34
306
1.12
0.21
3.1
2.4
0.23
2.54
estimate
0.44
13
99
5
43
1.16
0.21
1.0
1.0
299.80
268.41
ng/l
—
5
29
5
43
1.16
0.21
1.0
1.0
642.00
570.45
ng/l
—
5
29
0
14
0.00
0.20
0.0
2.0
—
3.79
—
0
14
0
14
0.00
0.20
0.0
1.1
—
0.73
—
0
6
0
14
0.00
0.20
0.0
3.0
—
5579.29
—
0
14
7
60
1.17
0.18
1.6
1.1
—
—
—
0
0
5
67
0.74
0.17
2.4
2.5
—
—
—
0
0
12
102
1.18
0.15
1.3
1.3
—
—
—
0
0
10
85
1.18
0.12
1.2
1.6
33.35
30.56
g/l
—
10
74
162
1579
1.03
0.12
3.0
3.0
357.23
353.26
umol/l
0.18
140
1402
25
230
1.09
0.11
3.4
4.1
181.69
241.67
mg/l
0.26
13
109
177
1730
1.03
0.11
1.5
1.4
—
—
—
0
0
26
280
0.93
0.10
1.8
1.8
—
—
—
0
0
5
48
1.04
0.09
1.0
1.4
—
—
—
0
0
71
685
1.04
0.09
1.3
1.4
—
—
—
0
0
57
593
0.96
0.09
4.1
4.7
83.80
32.82
ug/l
0.28
41
492
98
953
1.03
0.09
1.6
1.6
—
—
—
0
0
5
65
0.77
0.08
1.2
1.8
—
—
—
0
0
22
205
1.08
0.08
1.9
2.1
—
8053.09
u/l
—
0
77
23
215
1.07
0.07
1.6
1.6
24.13
8.10
u/ml
—
6
49
27
256
1.06
0.06
2.1
1.9
—
—
—
0
0
27
260
1.04
0.03
1.6
2.0
—
—
—
0
0
20
194
1.03
0.00
1.1
1.4
177.40
241.02
miu/ml
—
5
90
12
125
0.96
0.00
2.3
1.8
—
—
—
0
0
15
146
1.03
0.00
1.1
1.2
—
—
—
0
0
22
223
0.99
0.00
1.5
2.0
—
—
—
0
0
28
277
1.01
0.00
1.8
1.9
—
—
—
0
0
19
189
1.01
0.00
1.4
2.7
—
—
—
0
0
28
279
1.00
0.00
1.7
1.9
—
—
—
0
0
28
281
1.00
0.00
1.7
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
41.63
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
1.1
1.3
1023.14
1826.58
e6/l
—
7
48
6
64
0.94
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
2.94
—
0
9
8
87
0.92
-0.00
1.1
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
62.60
—
0
5
0
9
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
16.28
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
2.05
—
0
7
8
81
0.99
-0.00
1.5
1.2
—
98.12
—
0
6
6
66
0.91
-0.00
1.3
1.5
—
—
—
0
0
7
72
0.97
-0.00
2.3
1.8
—
—
—
0
0
7
70
1.00
-0.00
1.1
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
169.00
—
0
5

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: E4_PANHYPOPITUITARISM – Panhypopituitarism

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).