Benign neoplasm of breast

CD2_BENIGN_BREAST

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D24&
  • Hospital discharge: ICD-9 217
  • Hospital discharge: ICD-8 21799
  • Cause of death: ICD-10 D24&
  • Cause of death: ICD-9 217
  • Cause of death: ICD-8 21799

2 out of 7 registries used, show all original rules.

5485

4. Check minimum number of events

None

5485

5. Include endpoints

None

5485

6. Filter based on genotype QC (FinnGen only)

4929

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasma benignum mammae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 36691 36691 -
Only index persons 33454 33454 -
Unadjusted period prevalence (%)
Whole population 1.05 1.05 -
Only index persons 1.23 1.23 -
Median age at first event (years)
Whole population - 43.94 -
Only index persons - 42.89 -

-FinnGen-

Key figures

All Female Male
Number of individuals 4929 4929 -
Unadjusted period prevalence (%) 1.75 1.75 -
Median age at first event (years) 42.91 42.91 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5136
Matched controls
51360
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N63
ICD-10 Finland
Unspecified lump in breast
6.3
307.7
1358
2764
D24
ICD-10 Finland
Benign neoplasm of breast
2424.3
307.7
3493
45
21799
ICD-8 Finland
Benign neoplasm of breast
+∞
307.7
1019
*
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
36.4
307.7
1584
622
2170A
ICD-9 Finland
Benign neoplasm of breast[NEOPLASMA BENIGNUM MAMMAE]
+∞
307.7
689
*
HAB99
NOMESCO Finland
Other partial excision of mammary gland
7.8
307.7
583
834
9702
FHL
Breast exploration and possible tumor removal
20.0
307.7
591
332
N60.2
ICD-10 Finland
Fibroadenosis of breast
16.1
302.6
261
170
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
3.5
243.4
992
3282
HAA10
NOMESCO Finland
Biopsy of mammary gland
13.7
242.5
228
173
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
5.4
203.3
423
839
D48.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Breast
6.0
174.9
318
555
9703
FHL
Breast resection
9.0
163.5
204
234
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
4.4
158.1
417
1004
HAB40
NOMESCO Finland
Wedge excision of mammary gland
3.1
138.3
632
2199
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
3.5
135.4
495
1500
HA1AA
NOMESCO Finland
X-ray mammography
2.5
124.0
901
3986
N64.5
ICD-10 Finland
Other signs and symptoms in breast
4.0
112.8
332
864
N60.1
ICD-10 Finland
Diffuse cystic mastopathy
6.8
90.7
143
215
N64.9
ICD-10 Finland
Disorder of breast, unspecified
5.3
83.6
172
335
HA4GT
NOMESCO Finland
Labeling mammary gland pathology with galactographic guidance
18.3
81.1
65
36
HAB20
NOMESCO Finland
Excision of lactiferous duct
12.4
77.9
77
63
X19
ICPC
Breast lump/mass female
3.8
70.6
219
590
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
65.4
1241
7693
N60.8
ICD-10 Finland
Other benign mammary dysplasias
9.3
62.2
75
82
XX2AT
NOMESCO Finland
Other injection with ultrasound examination
4.2
61.4
165
400
R92
ICD-10 Finland
Abnormal findings on diagnostic imaging of breast
7.9
60.8
83
106
HA5CB
NOMESCO Finland
Galactography
12.8
58.9
57
45
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
3.3
58.2
224
695
HA3ST
NOMESCO Finland
Removal of lesion of breast with radiological guidance
7.6
57.2
81
108
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
3.6
55.0
182
512
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
2.3
52.9
449
2086
115
Kela drug reimbursment
Breast cancer
1.9
51.0
730
4110
C50.99
ICD-10 Finland
Breast, unspecified
2.7
49.7
288
1123
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
3.4
48.1
176
529
ZXE00
NOMESCO Finland
One hour or less
1.5
42.8
2015
15345
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
40.5
1955
14918
N60.0
ICD-10 Finland
Solitary cyst of breast
5.4
39.7
78
146
HAC20
NOMESCO Finland
Total mastectomy
2.2
39.1
353
1677
ZXA05
NOMESCO Finland
Left side
1.6
38.3
1243
8686
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
1.9
37.3
476
2568
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
3.4
35.3
130
393
PJA12
NOMESCO Finland
Sentinel node biopsy
1.8
34.4
607
3619
HA6BA
NOMESCO Finland
Breast tomosynthesis specimen
3.6
34.4
113
317
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
32.7
1236
8884
N64.8
ICD-10 Finland
Other specified disorders of breast
4.7
32.2
75
163
ZXA00
NOMESCO Finland
Right side
1.5
32.1
1303
9495
HA1AE, ,
SPAT
2.2
31.7
271
1258
X21
ICPC
Breast sympt/compl female other
2.5
30.3
195
800
N60.4
ICD-10 Finland
Mammary duct ectasia
9.1
29.5
36
40
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
3.1
29.1
121
394
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
2.5
29.0
192
798
N61
ICD-10 Finland
Inflammatory disorders of breast
2.5
29.0
188
774
WX402
NOMESCO Finland
General anaesthesia
1.5
28.5
1132
8184
HAE99
NOMESCO Finland
Other reconstruction of breast
3.9
28.0
83
217
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
2.5
27.9
181
745
N64.4
ICD-10 Finland
Mastodynia
2.1
27.8
263
1271
L02BA01
ATC
tamoxifen; oral
1.9
25.5
313
1662
Z2221
NOMESCO Finland
Medical doctor
1.4
25.3
1360
10375
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.9
24.7
341
1882
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
24.0
493
3052
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
2.0
24.0
283
1482
L02BG04
ATC
letrozole; oral
1.7
23.8
524
3305
61000
ICD-8 Finland
Chronic cystic disease of breast, Fibroadenomatosis mammae
3.9
23.6
69
179
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
2.6
23.3
132
509
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
2.0
23.1
261
1346
WX702
NOMESCO Finland
Supraglottic ventilation device
1.9
23.0
307
1675
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
2.7
22.9
123
462
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.9
22.5
301
1645
9719
FHL
Other measure in this category
7.7
20.8
29
38
D05.0
ICD-10 Finland
Lobular carcinoma in situ
6.2
20.6
35
57
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
3.3
20.6
77
236
THA00
NOMESCO Finland
Needle biopsy of mamilla
8.2
20.5
27
33
ZXD20
NOMESCO Finland
Day surgery
1.5
20.4
636
4344
TQW20
NOMESCO Finland
Tatoe
2.9
20.3
92
316
N60.9
ICD-10 Finland
Benign mammary dysplasia, unspecified
4.1
20.0
54
132
HA1RA, ,
SPAT
1.8
19.8
333
1951
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
19.7
1686
13754
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
19.5
1930
16064
J01DB01
ATC
cefalexin; oral
1.4
19.5
4123
38221
HA1TE
NOMESCO Finland
Supplementary or limited ultrasound examination of mammary glands
2.8
19.4
95
340
6101A
ICD-9 Finland
Benign mammary dysplasias, Diffuse cystic mastopathy
4.4
19.4
48
110
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
18.7
1965
16468
C50
ICD-10 Finland
Malignant neoplasm of breast
2.0
18.4
197
997
HA2AT
NOMESCO Finland
Cytology of mammary gland with ultrasound guidance
4.1
18.4
50
123
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
2.2
17.6
141
639
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
17.6
1825
15233
A02BC05
ATC
esomeprazole; systemic
1.3
17.0
2043
17361
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
17.0
1181
9298
17402
ICD-8 Finland
Malignant neoplasm of breast, Glandulae
5.4
16.8
33
62
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
4.0
16.6
46
115
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
16.2
291
1735
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.4
15.7
642
4616
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
2.3
15.2
115
509
C50.9
ICD-10 Finland
Malignant neoplasm: Breast, unspecified
3.1
15.1
62
202
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
14.4
1315
10725
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
1.6
14.4
312
1956
N02BE01
ATC
paracetamol; systemic, rectal
1.4
14.2
4572
43640
J02AC01
ATC
fluconazole; systemic
1.3
14.2
2343
20548
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
2.8
14.2
68
242
HAC25
NOMESCO Finland
Radical mastectomy
3.8
14.1
42
111
R4110
NOMESCO Finland
Physiotherapy
1.3
13.8
1280
10452
HA3RT
NOMESCO Finland
Coagulation of mammary neoplasm under radiological guidance
17.6
13.8
21
12
61099
ICD-8 Finland
Chronic cystic disease of breast, Unspecified
3.7
13.7
43
118
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.5
13.6
395
2650
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
2.1
13.5
125
601
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
2.1
13.5
126
608
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
2.5
13.0
83
342
X79
ICPC
Benign neoplasm breast female
13.0
12.9
22
17
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
12.9
1384
11500
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
12.6
1740
14892
HA1CM
NOMESCO Finland
Mammary gland extensive MRI examination with 3 Tesla magnet
4.1
12.5
33
80
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
1.4
12.4
526
3801
ZZF00
NOMESCO Finland
Graft of adipose tissue
2.8
12.4
60
215
C50.92
ICD-10 Finland
Malignant tumor in another specified localization in lobular gland, lobular tumor
3.5
12.3
42
122
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
1.8
12.2
184
1045
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
1.6
12.0
262
1645
S04
ICPC
Lump/swelling localized
1.4
12.0
552
4048
8520/2-C50.9
ICD-O-3
Lobular carcinoma in situ, NOS, of breast, NOS
10.0
12.0
23
23
HA3AT
NOMESCO Finland
Pucture of mammary gland cyst with ultrasound examination
2.8
11.9
57
203
D22
ICD-10 Finland
Melanocytic naevi
1.6
11.9
267
1689
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
2.3
11.8
84
364
EB1SA, ,
SPAT
1.6
11.5
239
1484
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
1.9
11.3
149
812
X18
ICPC
Breast pain female
2.1
11.3
111
547
H02AB02
ATC
dexamethasone; systemic
1.4
11.3
544
4019
N02AX02
ATC
tramadol; systemic, rectal
1.2
11.2
1898
16551
ZZR10
NOMESCO Finland
Flap of skin and muscle
2.8
11.2
53
188
Z00.0
ICD-10 Finland
General medical examination
1.3
11.1
857
6806
N62
ICD-10 Finland
Hypertrophy of breast
1.6
10.9
226
1402
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.4
10.7
499
3665
HAC10
NOMESCO Finland
Subcutaneous mastectomy with preservation of mamilla
4.9
10.7
23
47
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
4.4
10.7
26
59
R51.80
ICD-10 Finland
Headache
1.3
10.7
797
6295
HA3PT
NOMESCO Finland
Removal of mammary gland change by vacuum biopsy
60.1
10.6
12
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.2
10.6
3476
32342
1744A
ICD-9 Finland
Malignant neoplasm of female breast, Upper-outer quadrant
3.0
10.5
46
156
1742A
ICD-9 Finland
Malignant neoplasm of female breast, Upper-inner quadrant
5.0
10.5
22
44
ZSH00
NOMESCO Finland
Procedure related to previous procedure classified in chapter H
3.0
10.5
44
146
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
2.4
10.4
72
308
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
3.0
10.4
45
152
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
10.3
911
7359
HA1BG
NOMESCO Finland
MRI examination of mammary gland with high intensity magnet
2.5
10.2
61
244
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.2
10.1
1323
11195
HAD20
NOMESCO Finland
Liposuction of breast
5.0
10.0
21
42
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
2.7
10.0
53
200
C50.30
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, no histological veryfication
4.8
10.0
22
46
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
1.8
9.9
146
825
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
1.7
9.8
173
1029
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
2.0
9.8
106
543
HA1AT, ,
SPAT
4.0
9.8
27
68
L02BG06
ATC
exemestane; oral
1.9
9.7
122
656
Z01.2
ICD-10 Finland
Dental examination
1.2
9.7
2299
20633
D25.1
ICD-10 Finland
Intramural leiomyoma of uterus
1.5
9.7
336
2339
D01
ICPC
Abdominal pain/cramps general
1.3
9.7
632
4895
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
9.7
179
1080
X76
ICPC
Malignant neoplasm breast female
1.8
9.7
140
788
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
9.5
1040
8618
N03AX16
ATC
[U] pregabalin
1.3
9.4
1059
8796
Z31.5
ICD-10 Finland
Genetic counselling
1.5
9.4
270
1809
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
1.7
9.4
153
892
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.2
9.4
1481
12767
HA1HA
NOMESCO Finland
Tomosynthesis mammography
2.6
9.3
54
213
Z3226
NOMESCO Finland
Physiotherapist
1.3
9.3
773
6185
HWD00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of mammary gland
2.6
9.2
52
203
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
1.6
9.2
210
1338
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
1.5
9.1
254
1692
9706
FHL
Ablation mammae, includes axillary exploration
5.0
9.1
19
38
J01FA10
ATC
azithromycin; systemic
1.2
9.0
2854
26244
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.3
8.9
606
4718
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
8.9
780
6285
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
8.9
2446
22193
D05.9
ICD-10 Finland
Carcinoma in situ of breast, unspecified
3.7
8.9
27
73
J01MA02
ATC
ciprofloxacin; systemic
1.2
8.9
1615
14104
C07AA05
ATC
propranolol; systemic
1.3
8.8
962
7960
J01DA01
ATC
[U] cefalexin
1.2
8.7
2909
26827
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
1.7
8.7
141
822
HA4ST
NOMESCO Finland
Labeling mammary gland pathology with sterotactic guidance
3.1
8.6
35
114
SPAT1336
SPAT
Request for examination
1.7
8.6
156
936
C50.50
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, no histological veryfication
3.5
8.6
29
84
A97
ICPC
No disease
1.3
8.6
915
7547
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
2.9
8.5
38
131
C50.82
ICD-10 Finland
Overall malignant tumor of the mammary gland, lobular tumor
2.4
8.5
57
242
5702
FHL
Local lymph node removal (eg armpit, groin)
3.3
8.5
31
95
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
3.3
8.5
31
95
A03FA02
ATC
cisapride; oral, rectal
1.4
8.3
341
2451
C50.00
ICD-10 Finland
Malignant tumor of nipple and areola, no histological veryfication
2.7
8.3
43
161
23399
ICD-8 Finland
Neoplasm of unspecified nature of breast
3.7
8.2
25
68
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.3
8.2
649
5162
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.3
8.1
582
4563
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.5
8.1
284
1984
C50.31
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, ductal tumor
2.1
8.0
75
365
ZXA10
NOMESCO Finland
Bilateral
1.3
8.0
820
6727
UJF32
NOMESCO Finland
Coloscopy
1.2
8.0
1142
9716
S29
ICPC
Skin symptom/complaint other
1.2
8.0
969
8103
2393A
ICD-9 Finland
Neoplasm of unspecified nature, Breast
3.0
7.9
34
115
F45.8
ICD-10 Finland
Other somatoform disorders
1.4
7.9
329
2372
J01FF01
ATC
clindamycin; systemic
1.2
7.9
1151
9818
6117B
ICD-9 Finland
Other disorders of breast, Signs and symptoms in breast[TUMOR MAMMAE]
2.7
7.8
39
143
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
1.5
7.8
262
1813
A04AA02
ATC
granisetron; systemic, transdermal
1.5
7.8
275
1921
HA1SA
NOMESCO Finland
Expansion mammography
2.9
7.8
35
121
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
1.7
7.8
137
817
A02BC02
ATC
pantoprazole; systemic
1.2
7.7
3348
31420
9733
FHL
Excision of skin change in operating room or anesthesia
2.2
7.7
60
272
9707
FHL
Ablation of mammae and removal of axillary lymph nodes
2.5
7.6
44
174
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.2
7.6
2294
20871
XX2RW, ,
NOMESCO Finland
2.1
7.6
65
306
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
1.7
7.6
136
817
A02BC01
ATC
omeprazole; systemic
1.2
7.5
1232
10619
8113
FHL
Fractional scraping
1.4
7.5
373
2771
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.3
7.4
604
4815
Z3231
NOMESCO Finland
Registered nurse
1.2
7.4
1118
9558
R06.0
ICD-10 Finland
Dyspnoea
1.2
7.4
1212
10450
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.3
7.3
420
3189
N76.0
ICD-10 Finland
Acute vaginitis
1.4
7.3
347
2558
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.4
7.3
261
1831
R07.4
ICD-10 Finland
Chest pain, unspecified
1.2
7.3
1238
10703
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
2.0
7.3
78
400
U07
ICPC
Urine symptom/complaint other
1.3
7.2
410
3112
XX3DW
NOMESCO Finland
Time consuming IT work
1.3
7.2
427
3261
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
7.2
3229
30289
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.2
7.2
892
7473
HAB10
NOMESCO Finland
Microductectomy of mammary gland
20.0
7.1
10
5
C50.10
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, no histological veryfication
2.9
7.1
31
106
R42
ICD-10 Finland
Dizziness and giddiness
1.2
7.1
1109
9509
8503/2-C50.9
ICD-O-3
Noninfiltrating intraductal papillary adenocarcinoma of breast, NOS
7.9
7.1
15
19
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
2.3
7.0
52
231
R53
ICD-10 Finland
Malaise and fatigue
1.2
7.0
1198
10355
HAE05
NOMESCO Finland
Reconstruction of breast using soft tissue and prosthesis
2.7
7.0
35
129
N64
ICD-10 Finland
Other disorders of breast
3.4
7.0
24
71
2180A
ICD-9 Finland
Uterine leiomyoma, Submucous leiomyoma of uterus
1.4
6.9
313
2291
N30.0
ICD-10 Finland
Acute cystitis
1.2
6.9
1015
8648
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.4
6.9
368
2765
N06AX11
ATC
mirtazapine; oral
1.2
6.9
1628
14481
M01AE02
ATC
naproxen; oral, rectal
1.2
6.9
2683
24839
N05CF02
ATC
zolpidem; oral
1.2
6.9
799
6644
J01FA09
ATC
clarithromycin; systemic
1.2
6.9
1450
12776
L12
ICPC
Hand/finger symptom/complaint
1.2
6.9
813
6775
M03BX02
ATC
tizanidine; oral
1.2
6.8
2969
27721
61008
ICD-8 Finland
Chronic cystic disease of breast, Alia definita
4.1
6.8
18
44
C50.32
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, lobular tumor
3.8
6.8
20
53
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
1.9
6.8
86
467
N05CF01
ATC
zopiclone; oral
1.2
6.8
1451
12797
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.2
6.7
1052
9013
L03AA13
ATC
pegfilgrastim; parenteral
1.5
6.7
220
1519
C50.5
ICD-10 Finland
Malignant neoplasm: Lower-outer quadrant of breast
3.5
6.7
22
63
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
6.7
1591
14153
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.4
6.6
279
2019
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.3
6.6
414
3190
N80.1
ICD-10 Finland
Endometriosis of ovary
1.6
6.6
132
818
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.3
6.5
478
3758
P01AB01
ATC
metronidazole; oral, rectal
1.2
6.5
2006
18205
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
1.7
6.5
104
606
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
1.8
6.5
96
548
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
3.1
6.5
26
85
HA1ST
NOMESCO Finland
Biopsy of mammary gland with sterotactic guidance
3.9
6.4
18
46
XX2VW
NOMESCO Finland
Radiologic consultation
2.5
6.4
37
147
J02AC02
ATC
itraconazole; systemic
1.2
6.4
815
6842
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
2.6
6.4
34
130
H02AB07
ATC
prednisone; oral
1.3
6.3
579
4686
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
1.7
6.3
100
582
C50.93
ICD-10 Finland
Malignant tumor in other specified localization in mammary gland other or unspecified histology
3.2
6.3
24
76
A03CA05
ATC
glycopyrronium bromide and psycholeptics; systemic
2.1
6.2
53
250
HA5CB, ,
SPAT
26.7
6.2
8
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
1.5
6.2
182
1229
A48
ICPC
General and Unspecified, Clarification/discussion RFE/demand
1.4
6.2
265
1921
R01AD09
ATC
mometasone; nasal
1.2
6.2
2205
20210
C50.12
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,lobular tumor
2.6
6.2
34
132
R00.2
ICD-10 Finland
Palpitations
1.3
6.2
394
3041
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.3
6.2
441
3457
I97.2
ICD-10 Finland
Postmastectomy lymphoedema syndrome
2.5
6.2
35
138
N05BA04
ATC
oxazepam; oral
1.2
6.1
1239
10857
61199
ICD-8 Finland
Other diseases of breast, Other
5.7
6.1
16
28
J01AA02
ATC
doxycycline; systemic
1.2
6.1
3783
36135
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.5
6.1
160
1057
EB1AA, ,
SPAT
1.4
6.1
271
1981
A01AB09
ATC
miconazole; local oral
1.3
6.0
384
2964

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
810
1857
4.99
307.65
1.4
1.3
—
—
—
0
0
1147
6606
1.95
78.00
1.3
1.3
—
—
—
0
0
2748
20855
1.68
70.59
2.3
2.1
—
—
—
0
0
736
4512
1.74
38.07
1.4
1.4
—
—
—
0
0
2017
15961
1.43
32.48
2.3
2.2
—
—
—
0
0
257
1382
1.90
20.15
1.3
1.2
—
—
—
0
0
2612
22682
1.31
19.38
6.6
6.5
0.71
0.70
%
0.58
2456
21149
2670
23264
1.31
19.28
6.5
6.4
28.78
28.51
%
0.66
2537
21979
2615
22725
1.31
19.23
6.6
6.5
8.67
8.57
%
1.02
2458
21241
2609
22667
1.31
19.22
6.5
6.4
2.71
2.79
%
0.93
2451
21167
2625
22846
1.30
18.99
6.4
6.3
56.68
56.98
%
0.68
2507
21766
2816
24999
1.28
16.34
6.4
6.5
1.22
1.22
mmol/l
1.55
2449
21532
1473
12037
1.31
16.29
2.3
2.2
—
—
—
0
0
2542
22305
1.28
16.11
5.9
5.8
1.22
1.22
mmol/l
2.44
2334
20566
3932
36557
1.32
15.41
9.0
8.1
76.34
78.01
u/l
1.98
3735
34602
2767
24647
1.27
15.02
2.6
2.5
81.29
79.31
nmol/l
3.03
2497
22432
2835
25405
1.26
14.28
6.7
6.2
9.78
10.33
umol/l
3.74
2689
24098
3069
27880
1.25
13.18
10.0
9.6
3.90
3.99
e9/l
1.32
2632
24191
3608
33419
1.27
12.98
5.5
5.0
2.08
2.19
—
7
38
1301
10727
1.29
12.87
1.5
1.5
2.12
2.26
g/l
2.63
729
6455
2561
22883
1.24
12.47
2.8
2.7
—
—
estimate
—
0
0
1438
12048
1.27
12.41
3.7
3.7
94.55
94.26
%
0.18
1403
11740
4747
45796
1.48
12.32
17.0
15.5
20.38
21.60
mg/l
1.83
3916
37694
2828
25564
1.24
12.26
6.5
6.4
0.18
0.18
e9/l
0.43
2448
22309
929
7384
1.32
12.02
3.0
2.9
4.03
4.49
e6/l
0.46
409
3341
3847
36059
1.27
11.68
4.9
4.7
11.93
12.68
mm/h
2.98
3601
33790
2745
24806
1.23
11.66
6.3
6.3
0.04
0.04
e9/l
0.06
2332
21253
635
4795
1.37
11.57
3.6
4.2
7.37
7.36
ph
0.33
438
3324
2737
24738
1.23
11.57
6.3
6.2
0.56
0.56
e9/l
0.24
2324
21204
2790
25297
1.23
11.32
6.3
6.3
1.89
1.91
e9/l
0.56
2434
22236
221
1370
1.64
10.71
4.2
3.8
50.67
33.32
u/ml
0.56
215
1332
901
7295
1.29
9.97
1.2
1.2
—
—
—
0
0
731
5785
1.31
9.61
4.8
4.9
33.93
33.62
%
0.34
481
3800
2022
18000
1.20
9.14
4.1
3.9
104.27
107.50
e6/l
0.05
1321
12093
4612
44608
1.33
8.66
6.7
6.3
1.81
1.88
mu/l
3.71
4319
41685
1662
14600
1.20
8.49
3.4
3.2
0.08
0.04
0.30
36
345
507
3888
1.34
8.29
3.5
3.4
4.49
4.45
pmol/l
0.39
456
3464
2410
21922
1.19
8.27
2.2
2.1
101.60
99.12
pmol/l
1.42
1133
10733
2700
24810
1.19
8.22
3.3
3.2
91.25
94.26
ug/l
0.37
2512
23186
72
344
2.11
8.09
1.1
1.1
—
—
—
0
0
1472
12832
1.21
8.07
1.3
1.3
1.12
1.55
u/ml
1.23
333
3464
1787
15922
1.19
7.60
3.1
3.2
28.61
30.95
u/l
2.50
1683
14978
3477
32797
1.19
7.32
5.6
5.2
2729.70
2958.12
e6/l
0.06
61
390
1444
12660
1.20
7.31
3.2
3.1
3.71
249.75
estimate
—
8
52
979
8278
1.23
7.21
3.0
2.8
1.20
1.78
e6/l
0.78
472
4244
565
4490
1.29
7.13
1.2
1.2
—
—
—
0
0
1298
11295
1.20
7.10
1.8
1.7
0.97
1.13
mg/l
1.85
986
8737
2258
20642
1.17
6.79
13.1
12.9
1.20
1.20
inr
0.12
1850
17030
852
7151
1.23
6.71
2.1
2.2
105.90
119.77
ug/g
0.57
643
5605
2022
18348
1.17
6.63
4.1
3.4
2.37
2.37
mmol/l
0.88
1833
16621
1701
15227
1.18
6.61
3.3
3.3
37.37
61.07
e6/l
1.14
1221
11376
2303
21135
1.16
6.47
3.8
3.8
6.17
6.28
ph
4.54
1256
11567
598
4853
1.26
6.36
2.5
2.4
33.77
38.84
u/l
1.37
513
4039
1492
13251
1.18
6.33
3.2
3.2
0.31
0.41
e6/l
1.43
1013
9550
1677
15036
1.17
6.33
6.7
6.2
—
—
—
0
0
4129
39739
1.20
6.10
5.5
5.1
14.80
14.76
pmol/l
0.53
3825
36762
3287
31111
1.16
5.76
3.3
3.2
41.00
41.01
u/l
0.00
3062
29123
4751
46473
1.30
5.62
19.1
17.9
3.92
3.94
mmol/l
2.72
4658
45504
4743
46400
1.29
5.49
18.9
17.7
139.63
139.67
mmol/l
0.37
4662
45528
221
1603
1.40
5.22
1.9
1.9
—
—
—
0
0
4896
48152
1.36
5.09
22.0
20.0
69.36
69.76
umol/l
0.62
4851
47590
126
827
1.54
5.00
4.5
4.1
41.80
62.73
u/ml
0.86
126
818
1508
13608
1.15
4.98
2.9
3.0
1063.58
1135.76
ng/l
0.29
1277
11689
2843
26773
1.14
4.96
4.5
4.3
0.00
0.20
estimate
0.57
526
5404
513
4222
1.24
4.83
3.2
3.8
53.05
60.95
u/ml
0.14
501
4070
1577
14311
1.15
4.77
1.7
1.7
21.71
21.14
nmol/l
0.77
1297
12044
624
5251
1.21
4.74
4.2
4.0
22.55
27.10
ug/l
0.14
488
4166
242
1813
1.35
4.72
1.3
1.3
84.80
37.76
u/ml
0.68
11
120
2784
26240
1.13
4.66
4.4
4.3
0.00
0.00
estimate
1.34
523
5401
518
4298
1.23
4.53
3.1
3.2
78.30
80.84
ng/l
0.30
453
3629
1696
15514
1.14
4.50
4.2
3.9
7.40
7.40
ph
2.86
1183
11064
15
44
3.42
4.46
1.5
2.7
1.00
0.82
u/field
0.20
15
44
4866
47889
1.31
4.38
13.6
12.3
23.06
23.38
u/l
0.77
4739
46550
671
5732
1.20
4.35
1.3
1.3
—
—
—
0
0
2806
26542
1.13
4.25
4.4
4.3
3.10
3.63
estimate
0.06
539
5609
544
4567
1.21
4.24
2.1
2.1
0.21
0.21
g/l
0.67
506
4284
98
1484
0.65
4.24
8.1
9.7
—
—
—
0
0
93
594
1.58
4.22
1.1
1.1
—
—
—
0
0
119
804
1.49
4.19
1.1
1.1
—
—
—
0
0
85
533
1.60
4.17
1.1
1.2
—
—
—
0
0
1874
17322
1.13
4.14
3.6
3.7
24.24
73.62
ng/l
1.07
1216
11275
743
6437
1.18
4.10
2.0
1.9
—
—
—
0
0
118
803
1.48
4.02
1.1
1.1
—
—
—
0
0
592
5040
1.20
3.99
2.2
2.2
371.33
383.68
nmol/l
0.81
538
4659
220
1675
1.33
3.91
1.3
1.3
3.49
4.87
u/ml
0.24
18
171
228
1748
1.32
3.86
2.0
1.9
20.38
20.64
s
0.46
204
1505
162
1179
1.39
3.85
1.1
1.1
—
—
—
0
0
995
8874
1.15
3.75
2.8
2.9
490.39
492.29
mosm/kgh2o
0.10
857
7747
177
1314
1.36
3.73
2.2
2.3
3.45
3.57
g/l
0.61
171
1251
883
7815
1.16
3.70
1.7
1.7
—
—
—
0
0
2341
22024
1.12
3.68
4.5
4.6
36.28
35.85
g/l
3.66
2180
20538
1004
8974
1.15
3.67
3.7
3.8
239.47
258.12
ng/l
0.12
733
6581
1312
11938
1.13
3.66
4.0
4.1
—
—
—
0
0
217
1676
1.31
3.52
1.3
1.4
8.57
7.57
u/ml
0.09
37
267
780
6878
1.16
3.43
2.3
2.5
21.72
21.54
%
0.14
711
6326
4983
49306
1.36
3.43
26.5
24.0
261.55
263.67
e9/l
1.58
4895
48393
848
7524
1.15
3.43
2.3
2.4
2.40
2.39
g/l
0.30
776
6896
4983
49311
1.35
3.38
26.4
23.9
91.05
91.05
fl
0.03
4946
48845
4984
49324
1.35
3.37
26.7
24.1
131.14
131.50
g/l
1.42
4949
48870
1522
14037
1.12
3.34
3.9
3.6
0.05
0.35
estimate
1.65
430
4396
4983
49315
1.35
3.34
26.5
24.0
4.37
4.39
e12/l
1.98
4882
48239
653
5693
1.17
3.34
2.4
2.4
5.52
7.31
umol/l
3.53
549
4871
325
2658
1.24
3.31
2.1
2.0
—
—
—
0
0
4982
49312
1.34
3.26
26.4
23.9
30.16
30.15
pg
0.11
4945
48847
4982
49315
1.34
3.23
26.9
24.3
39.29
39.90
%
2.56
4944
48830
4982
49318
1.34
3.20
26.6
24.0
6.53
6.63
e9/l
2.41
4882
48232
189
1453
1.31
3.20
1.2
1.2
—
—
—
0
0
1424
13112
1.12
3.20
2.4
2.4
2.79
2.81
mg/l
0.08
1214
11353
150
1115
1.36
3.19
2.0
1.8
—
—
—
0
0
31
157
1.98
3.18
1.0
1.1
—
—
—
0
0
181
1390
1.31
3.10
1.3
1.3
32.39
42.05
u/ml
0.40
13
157
51
306
1.67
3.07
1.0
1.0
0.59
1.53
u/ml
0.72
12
78
129
943
1.38
3.06
3.4
3.5
22.73
23.78
mg/l
0.15
86
651
157
1186
1.33
3.02
1.1
1.1
—
—
—
0
0
233
1857
1.27
3.01
2.3
2.3
2.85
2.93
g/l
0.57
207
1665
2876
27520
1.10
3.01
4.7
4.5
6.47
6.53
mmol/l
1.00
2713
25842
610
5342
1.16
2.95
1.6
1.5
—
—
—
0
0
904
8137
1.13
2.95
2.4
2.5
12.81
12.82
umol/l
0.00
828
7518
301
2476
1.23
2.94
2.2
2.2
0.00
0.01
estimate
1.28
59
814
183
1420
1.30
2.92
1.5
1.5
1.12
1.15
ratio
0.23
121
837
243
1954
1.26
2.92
2.2
2.2
3.57
3.65
g/l
0.34
217
1764
243
1956
1.25
2.90
2.2
2.2
4.24
4.29
g/l
0.32
217
1761
243
1958
1.25
2.87
2.2
2.2
7.35
7.56
g/l
1.31
217
1765
212
1690
1.27
2.76
2.1
2.2
10.18
9.99
g/l
0.31
184
1473
180
1406
1.29
2.76
1.5
1.4
—
—
—
0
0
219
1753
1.26
2.75
1.6
1.8
345.70
316.63
mu/l
0.46
197
1563
129
967
1.34
2.66
1.4
1.4
0.31
0.41
nmol/l
1.65
104
735
248
2024
1.24
2.64
1.1
1.1
—
—
—
0
0
52
328
1.59
2.62
1.1
1.0
—
—
—
0
0
180
1419
1.28
2.59
1.3
1.3
2.30
18.25
u/ml
—
5
16
192
1526
1.27
2.58
1.5
1.5
61.60
60.12
ug/l
0.18
168
1267
714
6391
1.14
2.54
3.5
3.1
4.80
4.28
e9/l
0.41
588
5541
285
2371
1.21
2.53
2.1
1.9
7.65
6.72
iu/ml
0.23
53
565
79
550
1.44
2.53
1.5
1.5
—
2.40
—
0
5
144
1107
1.31
2.51
2.4
2.3
—
—
—
0
0
138
1055
1.32
2.51
1.4
1.3
17.16
15.57
u/l
0.47
112
864
176
1390
1.28
2.50
1.2
1.2
—
—
—
0
0
334
2835
1.19
2.41
1.1
1.1
—
2.14
—
0
28
1648
15491
1.09
2.35
2.7
2.6
58.12
59.31
u/l
0.22
1499
14249
54
354
1.53
2.34
2.1
2.8
9.99
25.97
mg/l
1.86
43
239
415
3597
1.17
2.34
1.5
1.4
—
—
—
0
0
284
2388
1.20
2.29
1.3
1.2
—
—
—
0
0
959
8802
1.11
2.23
2.0
1.9
—
—
—
0
0
7
19
3.69
2.15
1.0
1.1
—
—
—
0
0
577
5154
1.13
2.15
1.5
1.5
—
—
—
0
0
1071
9912
1.10
2.11
1.3
1.3
9.60
11.92
u/ml
0.61
379
3932
388
3377
1.16
2.10
1.3
1.3
57.34
50.22
au/ml
0.27
21
216
134
1051
1.28
2.07
3.8
4.6
—
—
—
0
0
26
146
1.78
2.06
1.0
1.1
—
—
—
0
0
66
466
1.42
2.03
1.6
1.4
—
1200.00
—
0
5
14
63
2.23
2.00
1.0
1.9
—
—
—
0
0
2114
20188
1.08
2.00
2.0
1.9
1.27
1.33
mmol/l
3.81
1761
16917
121
942
1.29
1.99
1.3
1.3
29.72
31.21
u/l
0.18
98
775
4487
44201
1.12
1.98
5.2
5.2
5.75
5.81
mmol/l
2.78
4108
40730
251
2121
1.19
1.96
1.6
1.6
22.13
15.25
u/ml
0.77
65
466
1874
17824
1.08
1.96
3.5
3.4
—
—
—
0
0
395
3463
1.15
1.95
1.3
1.3
147.55
200.94
u/ml
0.82
365
3228
1444
13591
1.09
1.95
1.6
1.5
—
—
—
0
0
95
718
1.33
1.94
1.3
1.3
—
—
—
0
0
144
1150
1.26
1.94
1.3
1.2
—
—
—
0
0
233
1958
1.20
1.94
1.7
1.7
—
—
—
0
0
857
7881
1.10
1.92
2.8
3.0
0.82
0.82
mmol/l
0.21
794
7378
368
3214
1.16
1.92
1.5
1.4
29.60
30.72
iu/l
0.24
314
2783
416
3666
1.15
1.92
2.4
2.4
27.03
23.10
au/ml
0.32
46
418
439
3890
1.14
1.87
1.3
1.3
—
—
—
0
0
829
7632
1.10
1.82
1.5
1.4
650.16
567.72
titre
0.46
189
1777
1326
12481
1.08
1.78
4.0
4.2
0.20
0.57
—
10
124
413
3659
1.14
1.78
8.1
7.4
—
—
—
0
0
209
1756
1.20
1.77
1.9
2.0
137.50
7.03
iu/l
0.72
68
738
22
124
1.78
1.75
1.3
1.2
—
—
—
0
0
68
498
1.37
1.74
1.1
1.2
120.22
113.82
pmol/l
0.42
68
498
30
186
1.62
1.71
1.2
1.2
—
0.30
g/l
—
0
11
286
2476
1.16
1.71
3.0
3.6
24.47
24.46
mmol/l
0.03
281
2453
288
2499
1.16
1.68
9.2
7.8
24.44
24.42
mmol/l
0.04
276
2451
41
276
1.49
1.66
1.0
1.0
0.05
0.25
u/ml
—
8
69
93
721
1.30
1.64
1.2
1.1
2.01
3.78
eliau/ml
1.30
44
309
51
361
1.42
1.60
7.5
6.6
15.96
91.84
ug/l
0.77
27
213
1132
10630
1.08
1.60
1.4
1.4
32.16
33.21
iu/ml
0.09
356
3359
13
63
2.07
1.59
4.3
8.0
4.93
5.60
kpa
1.35
13
63
15
77
1.95
1.59
1.1
1.1
20.63
7.37
u/ml
0.44
15
77
23
136
1.69
1.58
1.1
1.2
—
—
—
0
0
7
26
2.69
1.58
1.0
1.0
—
—
—
0
0
45
313
1.44
1.56
1.0
1.1
0.50
1.99
u/ml
0.75
15
103
408
3649
1.13
1.55
2.3
2.3
0.39
0.46
e6/l
0.42
390
3466
74
562
1.32
1.53
1.1
1.1
1.54
1.51
g/l
0.26
69
502
7
27
2.59
1.51
1.0
1.0
—
19.20
—
0
5
207
1768
1.18
1.50
1.3
1.3
216.99
235.74
miu/ml
0.36
119
870
288
2527
1.15
1.47
3.4
3.5
1.02
1.02
ratio
0.05
258
2256
192
1634
1.18
1.46
1.5
1.4
264.89
288.41
ug/g
0.92
98
932
32
211
1.52
1.45
1.4
1.5
14.90
14.77
pmol/l
0.06
27
172
545
4975
1.11
1.45
2.5
2.5
1.75
1.84
%
1.27
462
4409
637
5863
1.10
1.44
1.5
1.4
—
—
—
0
0
6
22
2.73
1.43
1.0
1.9
—
—
—
0
0
305
2695
1.14
1.42
2.4
2.4
—
—
—
0
0
22
133
1.66
1.42
2.0
2.2
—
—
—
0
0
59
439
1.35
1.42
1.3
1.2
—
—
—
0
0
599
5505
1.10
1.40
1.8
1.7
—
—
—
0
0
4617
45682
1.11
1.40
5.9
5.8
2.79
2.79
mmol/l
0.11
4274
42525
15
81
1.85
1.40
1.1
1.0
0.36
1.42
u/ml
—
5
50
69
527
1.31
1.40
2.1
2.7
—
—
—
0
0
35
238
1.47
1.39
1.5
1.6
2.11
1.97
umol/l
0.51
26
218
429
3877
1.12
1.39
7.1
6.2
1.21
1.27
mmol/l
0.79
421
3808
39
272
1.44
1.37
2.2
2.2
404.00
509.41
e6/l
1.05
31
211
14
248
0.56
1.35
1.6
1.3
53.00
68.37
%
—
6
30
76
593
1.29
1.33
1.8
2.0
36.32
26.03
mg/l
0.65
28
219
431
3907
1.11
1.33
2.5
2.6
66.40
66.47
g/l
0.08
390
3545
7
150
0.47
1.30
1.9
2.5
129.86
159.02
nmol/l
—
7
134
142
1191
1.20
1.30
1.5
1.5
—
—
—
0
0
49
659
0.74
1.30
1.3
1.3
6.39
7.29
mmol/l
1.81
36
587
3912
38479
1.07
1.29
21.6
19.1
13.58
13.61
%
1.09
3881
37984
5
18
2.78
1.28
1.0
1.1
—
—
—
0
0
4526
44769
1.09
1.28
5.1
4.9
1.61
1.58
mmol/l
4.05
4177
41576
166
1416
1.18
1.26
1.1
1.1
0.53
0.59
ratio
1.15
31
200
311
2777
1.13
1.26
1.3
1.2
—
—
—
0
0
1123
10641
1.07
1.25
3.2
2.8
2.46
2.46
mmol/l
0.05
1014
9541
60
458
1.31
1.25
2.4
2.7
—
—
—
0
0
101
823
1.23
1.24
1.3
1.3
0.30
0.26
nmol/l
—
5
45
16
92
1.74
1.24
5.6
4.8
25.56
24.72
mmol/l
0.67
16
85
13
70
1.86
1.23
4.3
7.8
5.73
5.79
kpa
0.10
13
63
462
4226
1.10
1.21
3.0
2.9
6.11
6.12
ph
0.09
294
2819
139
1173
1.19
1.21
1.5
1.5
1.27
1.27
mm
0.01
111
829
532
4902
1.10
1.20
1.9
1.9
3.14
3.24
ratio
1.31
417
3658
163
1396
1.17
1.20
2.5
3.5
25.36
25.08
mmol/l
0.78
147
1269
48
357
1.35
1.19
1.2
1.1
32.95
33.67
mmol/l
0.07
36
308
1398
14612
0.94
1.19
3.3
3.3
38.60
37.03
mg/l
0.09
739
8414
81
648
1.25
1.19
1.0
1.1
0.42
0.13
u/ml
0.45
28
193
160
1371
1.17
1.17
2.9
3.1
3.13
1.96
index
0.76
69
672
144
1223
1.18
1.17
1.6
1.5
—
—
—
0
0
87
704
1.24
1.16
1.3
1.3
0.19
0.21
nmol/l
0.34
68
538
0
33
0.00
1.16
0.0
3.0
—
754.94
—
0
33
8
39
2.05
1.15
1.1
1.5
—
—
—
0
0
13
72
1.81
1.15
1.0
1.0
—
—
—
0
0
13
72
1.81
1.15
1.0
1.0
—
—
—
0
0
13
72
1.81
1.15
1.0
1.0
—
—
—
0
0
466
4279
1.10
1.14
1.3
1.2
162.53
149.09
u/ml
0.26
163
1664
111
1328
0.83
1.14
2.6
3.7
1.28
1.34
mmol/l
0.20
111
1304
90
733
1.23
1.14
1.3
1.2
3.55
4.06
u/ml
0.15
44
311
66
519
1.28
1.13
2.6
2.2
—
—
—
0
0
146
1247
1.18
1.12
2.9
3.0
1.40
1.48
mg/l
0.78
126
1132
20
127
1.58
1.11
1.1
1.2
—
—
—
0
0
285
2555
1.12
1.11
2.8
3.4
7.43
7.42
ph
1.34
233
2116
61
479
1.28
1.06
1.3
1.2
—
—
—
0
0
377
4123
0.91
1.06
4.1
3.5
1.23
1.24
mmol/l
0.21
313
3530
32
228
1.41
1.05
1.0
1.1
3.50
5.40
u/ml
—
5
34
129
1099
1.18
1.04
2.0
2.2
127.96
126.70
g/l
0.26
94
848
69
552
1.25
1.04
5.8
5.0
38.27
104.57
u/ml
1.23
26
177
138
1183
1.17
1.04
1.3
1.3
—
—
—
0
0
211
1867
1.14
1.03
1.1
1.1
—
—
—
0
0
7
35
2.00
1.00
1.0
1.3
0.15
0.15
umol/l
—
7
35
54
423
1.28
0.98
1.1
1.1
10.01
8.05
iu/ml
0.24
13
103
101
848
1.19
0.98
1.1
1.2
—
—
—
0
0
36
266
1.36
0.97
3.5
3.5
—
—
—
0
0
291
2636
1.11
0.97
2.7
3.4
5.24
5.18
kpa
0.59
279
2517
0
31
0.00
0.96
0.0
1.8
—
62.32
—
0
22
94
786
1.20
0.96
1.1
1.1
—
—
—
0
0
631
5921
1.07
0.95
4.6
4.8
1.05
1.04
mmol/l
0.42
565
5414
4542
45022
1.08
0.95
5.2
5.0
4.83
4.81
mmol/l
0.95
4221
42060
91
759
1.20
0.95
1.2
1.3
65.18
61.69
u/ml
—
5
57
34
250
1.36
0.95
1.4
1.3
—
—
—
0
0
93
779
1.20
0.93
1.6
1.5
2.75
3.85
ug/l
1.46
82
678
43
330
1.31
0.92
1.2
1.4
32.56
22.31
umol/l
1.04
38
298
33
244
1.35
0.90
3.8
3.7
—
—
—
0
0
711
6718
1.07
0.89
1.9
1.9
29.37
29.14
s
0.35
695
6512
1101
10542
1.06
0.89
2.6
2.7
7.11
7.89
e6/l
1.09
1004
9563
388
3585
1.09
0.88
2.5
2.9
4.46
4.44
kpa
0.09
378
3492
63
511
1.24
0.88
5.0
6.4
12.51
12.55
mg/l
0.03
57
477
99
841
1.18
0.87
1.3
1.3
—
20.01
—
0
14
198
1769
1.12
0.87
2.6
3.4
—
—
—
0
0
64
781
0.82
0.86
3.0
2.1
0.85
0.84
nmol/l
0.06
56
670
52
415
1.26
0.84
2.4
2.2
1120.87
1243.54
e6/l
0.40
45
361
13
80
1.63
0.84
1.2
1.1
—
—
—
0
0
6
31
1.94
0.84
1.2
1.5
—
—
—
0
0
96
1125
0.85
0.84
2.6
4.0
3.92
3.79
mmol/l
1.65
96
1119
4296
42544
1.06
0.83
4.3
4.2
1.21
1.24
mmol/l
3.72
3931
39036
125
1088
1.15
0.82
1.7
1.9
4.92
5.00
mmol/24h
0.10
106
957
21
147
1.43
0.80
2.3
2.6
0.59
0.62
mmol/l
0.63
21
147
156
1383
1.13
0.79
1.3
1.2
117.69
168.65
titre
0.36
13
126
2195
21428
1.04
0.79
11.4
11.1
0.00
0.00
e9/l
0.76
1709
17410
84
712
1.18
0.78
3.5
3.3
1.01
1.48
%
1.49
75
640
12
74
1.62
0.78
1.0
1.3
58.75
63.54
ug/l
0.59
12
74
533
5660
0.93
0.78
1.9
1.7
—
—
—
0
0
27
199
1.36
0.78
1.2
1.1
474.67
309.51
ng/l
—
6
53
0
27
0.00
0.77
0.0
1.7
—
558.01
—
0
27
3860
38146
1.05
0.76
22.0
20.1
330.62
330.49
g/l
0.41
3842
37942
19
268
0.71
0.76
2.2
2.4
613.17
611.58
ml
0.01
12
187
542
5109
1.07
0.76
2.2
2.2
0.02
0.02
estimate
0.09
83
1007
60
495
1.21
0.75
2.6
3.1
14.55
14.14
index
0.09
33
251
186
1676
1.11
0.74
1.4
1.3
—
—
—
0
0
60
496
1.21
0.73
1.5
1.4
—
—
—
0
0
7
38
1.84
0.73
1.0
1.1
—
—
—
0
0
19
133
1.43
0.73
1.2
1.3
—
—
—
0
0
1435
14801
0.96
0.72
3.9
4.0
6.93
7.74
mg/mmol
0.30
756
8385
396
3700
1.08
0.72
1.7
1.7
3.45
3.47
mmol/l
0.06
283
2499
23
168
1.37
0.71
1.1
1.0
14.50
10.82
u/ml
0.28
13
113
5
26
1.92
0.70
1.0
1.0
—
—
—
0
0
15
217
0.69
0.70
12.2
13.5
767.00
6815.12
nmol/l
0.51
15
209
287
2651
1.09
0.70
2.7
2.8
127.15
127.27
g/l
0.03
282
2565
15
101
1.49
0.70
2.1
2.7
—
—
—
0
0
88
758
1.16
0.69
1.1
1.1
2.02
3.44
u/ml
0.83
39
358
1118
11581
0.96
0.68
4.6
4.5
1.02
1.41
kg/l
1.08
784
7715
87
751
1.16
0.67
2.0
2.0
4.84
5.73
umol/l
0.49
51
543
852
8171
1.05
0.67
1.8
1.7
1124.87
1188.17
nmol/l
1.12
610
6180
46
374
1.23
0.67
1.1
1.1
—
—
—
0
0
21
153
1.37
0.67
1.4
1.7
0.53
0.49
e9/l
0.21
21
153
7
43
1.63
0.66
2.3
1.2
—
—
—
0
0
76
650
1.17
0.66
1.1
1.2
—
—
—
0
0
28
214
1.31
0.66
2.0
1.7
3.95
1.52
u/ml
—
9
55
16
226
0.71
0.66
12.4
18.7
1200.88
5712.44
nmol/l
0.55
16
218
36
287
1.26
0.63
2.5
2.3
172.37
218.22
e6/l
1.04
30
236
29
225
1.29
0.63
1.1
1.3
142.71
138.69
mmol/24h
0.10
29
225
283
2628
1.08
0.63
1.1
1.1
58.00
180.00
titre
—
5
72
456
4309
1.06
0.62
3.2
3.4
7.38
7.38
ph
0.08
255
2378
49
406
1.21
0.62
1.2
1.3
1.74
1.40
u/ml
0.11
32
213
402
4267
0.94
0.61
4.7
4.6
0.10
0.47
%
1.55
101
996
171
1554
1.10
0.61
3.0
3.2
31.62
37.57
mg/l
0.59
142
1323
171
1555
1.10
0.61
3.1
3.2
35.73
82.51
mg/l
0.75
142
1327
116
1032
1.13
0.61
1.3
1.4
52.99
60.56
mmol/l
1.82
100
817
438
4138
1.06
0.60
3.1
3.4
2.06
1.95
mmol/l
0.28
402
3683
213
1959
1.09
0.60
1.9
1.7
1.57
1.58
g/l
0.05
182
1680
64
546
1.17
0.59
2.5
2.9
—
—
—
0
0
44
363
1.21
0.58
2.2
2.2
1.90
1.86
u/field
0.03
29
193
4320
42882
1.05
0.58
6.2
6.2
38.26
38.67
mmol/mol
2.98
4038
40120
452
4281
1.06
0.58
3.1
3.4
5.86
5.81
kpa
0.65
442
4182
414
4380
0.94
0.58
4.4
4.4
0.92
0.90
%
0.05
112
1221
40
327
1.22
0.58
1.1
1.1
10.38
13.91
nmol/l
—
7
59
45
373
1.21
0.57
1.3
1.3
2.22
2.09
mmol/l
0.17
37
351
407
3845
1.06
0.57
2.4
2.5
70.51
70.68
e9/l
0.03
295
2761
182
1667
1.10
0.57
2.3
1.9
0.24
0.23
g/l
0.40
172
1578
47
393
1.20
0.55
1.2
1.2
—
—
—
0
0
51
602
0.85
0.55
2.0
2.4
—
—
—
0
0
15
107
1.40
0.55
1.5
1.5
—
—
—
0
0
12
171
0.70
0.54
2.3
1.9
0.00
0.02
estimate
0.50
12
171
8
125
0.64
0.54
2.0
2.5
—
119.75
—
0
22
15
205
0.73
0.54
1.8
2.4
528.22
501.86
min
—
9
156
9
61
1.48
0.53
15.1
10.0
0.23
0.18
%
—
9
61
100
891
1.12
0.53
1.1
1.1
0.65
0.90
u/ml
0.28
46
367
1523
14867
1.03
0.53
2.1
2.1
160.33
163.31
u/l
0.06
1438
14015
86
759
1.14
0.53
1.3
1.3
148.66
156.76
au/ml
0.29
29
203
51
433
1.18
0.52
2.7
3.7
—
—
—
0
0
117
1296
0.90
0.52
4.9
5.9
1.18
1.23
mmol/l
0.29
110
1148
60
694
0.86
0.52
1.5
1.5
—
—
—
0
0
23
293
0.78
0.52
1.4
1.2
0.55
0.61
ratio
0.38
12
176
79
695
1.14
0.51
1.8
2.2
—
—
—
0
0
310
2916
1.07
0.51
2.2
1.9
1.30
1.37
g/l
0.31
287
2672
331
3509
0.94
0.51
2.3
2.9
205.05
169.81
ng/l
0.78
294
3212
39
468
0.83
0.51
3.1
2.6
10.15
10.49
mmol/l
0.26
39
460
320
3396
0.94
0.51
2.1
2.3
6.02
5.77
ug/l
0.11
264
2892
81
714
1.14
0.51
1.1
1.1
3.45
3.39
u/ml
0.01
31
298
6
40
1.50
0.51
1.0
1.4
—
—
—
0
0
6
40
1.50
0.51
4.3
13.1
3.95
4.96
mmol/l
—
6
40
48
406
1.18
0.51
2.8
2.5
28.71
25.42
mg/l
0.24
29
281
34
278
1.22
0.51
1.1
1.2
—
—
—
0
0
95
847
1.12
0.51
1.3
1.3
—
—
—
0
0
15
109
1.38
0.50
1.2
1.1
24.42
31.82
iu/ml
0.30
15
109
19
144
1.32
0.50
2.2
2.9
24.07
26.75
umol/l
0.63
14
109
16
118
1.36
0.50
1.2
1.3
—
—
—
0
0
68
776
0.87
0.49
1.1
1.5
—
15.40
—
0
17
67
765
0.87
0.49
2.0
2.5
33.10
32.11
umol/l
0.11
61
690
1193
11616
1.04
0.49
2.3
2.4
310.52
316.44
umol/l
1.31
1035
10167
149
1368
1.09
0.47
2.8
3.0
2.08
4.11
ratio
1.09
77
794
34
409
0.83
0.47
1.1
1.1
—
—
—
0
0
1535
15686
0.97
0.47
3.2
3.3
6.59
6.50
mmol/l
0.33
1269
13184
97
872
1.11
0.46
3.0
3.4
2.77
2.67
mmol/l
0.11
64
612
401
4209
0.95
0.46
4.5
4.4
0.07
0.11
%
0.71
99
1053
5
85
0.59
0.45
1.8
1.2
—
—
—
0
0
114
1038
1.10
0.44
1.4
1.3
—
—
—
0
0
34
405
0.84
0.43
1.1
1.1
—
—
—
0
0
102
925
1.10
0.43
1.1
1.1
5.46
4.21
u/ml
0.25
49
463
94
850
1.11
0.42
1.1
1.1
1.25
1.29
u/ml
0.01
45
405
5
32
1.56
0.42
2.2
2.1
0.54
0.59
ug/l
—
5
32
508
4882
1.05
0.42
7.2
6.7
1.15
1.07
mmol/l
0.21
437
4070
419
4009
1.05
0.41
4.9
4.2
—
—
—
0
0
13
96
1.36
0.41
1.5
2.1
14.67
17.10
umol/l
0.43
13
96
24
294
0.82
0.41
1.0
1.0
853.37
354.26
ng/l
0.51
19
211
131
1206
1.09
0.41
1.6
1.6
14182.92
10871.48
e6/l
0.36
96
822
0
15
0.00
0.41
0.0
1.1
—
0.02
—
0
6
0
17
0.00
0.40
0.0
1.1
—
0.07
—
0
12
0
18
0.00
0.40
0.0
1.0
—
94.20
—
0
10
0
18
0.00
0.40
0.0
1.0
—
0.14
—
0
8
39
334
1.17
0.39
1.1
1.1
—
—
—
0
0
5
35
1.43
0.39
4.8
1.9
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
5
36
1.39
0.38
4.0
1.8
41.80
45.86
umol/l
—
5
36
183
1715
1.07
0.38
2.3
1.9
1.19
1.20
g/l
0.19
174
1628
17
213
0.80
0.36
2.0
2.3
46.96
45.09
%
0.18
11
126
31
263
1.18
0.35
1.1
1.1
—
—
—
0
0
52
461
1.13
0.34
3.0
3.2
52.48
56.42
%
0.62
46
403
99
910
1.09
0.34
3.2
3.5
—
—
—
0
0
25
297
0.84
0.33
1.0
1.0
778.72
750.84
ng/l
0.09
18
202
14
109
1.29
0.33
1.2
1.1
0.82
0.65
umol/24h
—
5
48
244
2329
1.05
0.30
1.4
1.3
1.14
1.12
u/ml
0.01
18
202
64
581
1.10
0.30
1.5
1.7
405.69
366.69
mu/l
0.34
52
462
1991
19664
1.02
0.29
4.4
4.2
1.20
0.46
estimate
0.28
434
4385
151
1424
1.06
0.29
1.1
1.1
2.36
8.14
eliau/ml
2.17
19
163
133
1251
1.06
0.28
1.6
1.7
—
—
—
0
0
169
1602
1.06
0.28
1.7
1.9
1.83
1.94
ug/l
0.06
141
1410
18
215
0.84
0.27
3.2
2.1
15.60
15.66
%
0.03
18
215
97
904
1.07
0.27
1.1
1.1
11.68
17.66
au/ml
0.78
22
194
14
113
1.24
0.26
1.2
1.1
—
—
—
0
0
12
95
1.26
0.26
1.0
1.1
—
288.00
—
0
5
76
703
1.08
0.25
1.2
1.2
—
—
—
0
0
20
169
1.18
0.25
1.1
1.1
—
—
—
0
0
9
72
1.25
0.25
1.0
1.1
—
—
—
0
0
9
72
1.25
0.25
1.2
1.5
—
—
—
0
0
9
73
1.23
0.25
1.0
1.0
—
—
—
0
0
74
799
0.93
0.25
2.4
2.4
18.18
62.58
ug/min
3.20
39
455
18
213
0.84
0.25
1.4
1.6
—
—
—
0
0
365
3539
1.03
0.24
5.7
6.4
8.80
9.12
mmol/l
0.42
348
3386
182
1740
1.05
0.23
1.5
1.4
—
—
—
0
0
84
784
1.07
0.23
1.1
1.2
—
—
—
0
0
505
4925
1.03
0.23
7.4
6.7
7.42
7.42
ph
0.18
268
2629
106
1124
0.94
0.23
1.6
1.4
1985.82
1253.75
e6/l
0.23
77
881
40
361
1.11
0.23
1.1
1.1
—
—
—
0
0
7
92
0.76
0.22
1.0
1.7
—
—
—
0
0
159
1518
1.05
0.22
2.6
2.9
854.18
448.78
mg/l
0.44
62
531
5
41
1.22
0.22
1.2
1.2
—
—
—
0
0
106
1001
1.06
0.22
3.0
3.4
0.73
0.81
nmol/l
1.54
85
818
88
826
1.07
0.22
1.5
1.5
0.92
0.63
g/l
0.72
68
632
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
2691.50
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
24.34
—
0
7
0
14
0.00
0.20
0.0
1.1
—
0.16
—
0
7
6
48
1.25
0.20
1.0
1.0
—
—
—
0
0
62
666
0.93
0.20
1.2
1.2
22.25
26.40
u/l
0.26
52
573
25
221
1.13
0.20
1.7
2.4
85.42
161.20
umol/l
2.07
12
124
87
820
1.06
0.20
1.1
1.2
275.72
266.95
u/ml
0.09
50
515
14
165
0.85
0.19
1.2
1.7
27.21
28.58
%
0.16
14
155
24
213
1.13
0.18
3.3
3.0
—
—
—
0
0
273
2652
1.03
0.18
1.6
1.6
1062.56
1003.68
mu/l
0.44
236
2212
12
100
1.20
0.18
6.3
4.0
37.17
64.35
u/l
0.87
12
95
33
362
0.91
0.17
1.5
1.2
80.00
200.00
titre
—
5
72
62
661
0.94
0.17
1.3
1.1
43.32
16537.23
iu/ml
0.55
18
144
22
195
1.13
0.17
2.2
2.0
42.54
39.95
g/l
1.99
22
195
29
262
1.11
0.17
9.8
13.7
0.55
0.63
mmol/l
1.43
24
236
1778
17626
1.01
0.17
3.1
3.1
—
—
—
0
0
107
1121
0.95
0.17
1.2
1.2
3.61
3.71
mmol/l
0.51
101
1069
130
1247
1.04
0.17
1.5
1.4
—
—
—
0
0
17
148
1.15
0.16
1.2
1.1
—
—
—
0
0
26
288
0.90
0.16
1.4
1.6
1.35
1.02
promille
0.62
20
221
22
246
0.89
0.16
1.4
1.5
1.16
1.34
nmol/l
0.36
15
179
16
139
1.15
0.16
1.4
1.3
165.18
104.72
nmol/l
0.82
11
99
6
77
0.78
0.15
2.2
1.6
—
—
—
0
0
106
1107
0.96
0.15
1.5
1.3
136.43
28.19
e6/l
0.44
72
812
20
224
0.89
0.15
1.2
1.2
—
—
—
0
0
72
758
0.95
0.14
1.8
1.5
47.11
54.27
mu/l
0.20
63
683
7
86
0.81
0.14
1.9
2.0
4.43
5.93
ug/l
—
7
86
7
87
0.80
0.14
4.1
4.9
—
—
—
0
0
48
512
0.94
0.14
1.4
1.4
—
—
—
0
0
109
1048
1.04
0.14
3.9
3.3
58.73
57.66
%
0.43
109
1048
230
2242
1.03
0.14
2.2
2.7
0.57
0.62
%
2.22
230
2229
16
141
1.14
0.13
1.2
1.4
5.16
6.97
mmol/l
1.56
16
141
16
141
1.14
0.13
1.1
1.0
0.08
2.12
u/ml
—
6
72
25
274
0.91
0.13
1.4
1.5
74.20
71.62
umol/l
0.23
25
274
8
98
0.82
0.13
1.3
1.0
—
—
—
0
0
19
170
1.12
0.13
1.1
4.0
91.91
60.66
mg/l
0.80
11
115
12
138
0.87
0.13
1.0
1.1
—
—
—
0
0
12
138
0.87
0.13
1.0
1.1
—
—
—
0
0
12
138
0.87
0.13
1.0
1.1
—
—
—
0
0
42
448
0.94
0.13
2.7
2.1
1.20
1.21
mmol/l
0.36
42
443
232
2265
1.03
0.13
2.4
2.2
5529.88
5759.61
u/l
0.04
108
913
262
2678
0.98
0.12
9.8
8.1
0.62
0.65
%
0.57
262
2665
13
148
0.88
0.12
1.8
2.0
1213.14
713.31
e6/l
—
7
93
30
324
0.93
0.12
1.8
1.9
6.23
6.39
mmol/l
0.15
21
226
379
3724
1.02
0.12
3.0
3.0
10.00
10.39
g/l
1.25
351
3437
24
220
1.09
0.11
1.4
1.8
—
—
—
0
0
52
493
1.06
0.11
1.4
1.3
—
—
—
0
0
505
4980
1.02
0.11
1.7
1.8
—
—
—
0
0
40
376
1.06
0.11
1.2
1.4
—
—
—
0
0
50
474
1.06
0.11
9.0
3.4
8.41
7.12
mmol/l
1.01
42
397
43
455
0.94
0.11
2.7
2.1
106.47
105.46
mmol/l
1.00
43
450
43
455
0.94
0.11
2.7
2.1
3.99
4.00
mmol/l
0.06
43
450
83
862
0.96
0.11
1.5
1.5
—
—
—
0
0
35
328
1.07
0.11
1.1
1.1
18.50
16.13
u/ml
0.13
14
144
16
144
1.11
0.10
1.0
1.2
40.50
38.10
g/l
—
8
66
201
1967
1.02
0.10
1.6
1.6
5.78
16.42
iu/ml
—
6
48
155
1589
0.97
0.10
1.5
1.5
0.27
0.29
mg/l
0.16
63
618
20
218
0.92
0.10
2.5
1.8
7.94
8.17
mmol/l
0.10
20
218
50
523
0.96
0.09
1.4
1.4
0.31
0.40
g/l
1.87
35
376
50
523
0.96
0.09
1.4
1.4
6.06
6.70
g/l
0.77
36
373
50
523
0.96
0.09
1.4
1.4
2.40
2.87
g/l
1.20
36
374
40
380
1.05
0.08
1.2
1.3
—
—
—
0
0
38
400
0.95
0.08
1.2
1.4
5232.13
62033.75
e6/l
1.87
15
204
39
410
0.95
0.08
1.4
1.8
—
—
—
0
0
5
61
0.82
0.08
1.0
1.1
0.02
0.02
u/ml
—
5
61
7
64
1.09
0.08
1.1
1.4
—
144.56
—
0
7
136
1330
1.02
0.08
1.8
2.1
11.48
11.70
mg/l
0.09
123
1238
6
71
0.84
0.07
1.7
2.5
—
—
—
0
0
6
72
0.83
0.07
2.0
6.3
7.22
8.15
mmol/l
—
6
72
25
266
0.94
0.07
1.1
1.1
1747.84
1508.23
miu/ml
0.42
25
266
7
84
0.83
0.07
3.1
2.7
64.86
1937.87
u/l
—
7
77
496
4917
1.01
0.06
7.3
6.7
12.89
12.65
kpa
0.44
484
4713
175
1722
1.02
0.06
3.4
3.2
376.74
1048.58
u/ml
0.87
147
1470
9
100
0.90
0.06
1.0
1.2
3.75
3.29
mmol/l
—
9
90
20
187
1.07
0.06
2.4
2.0
30.95
30.13
%
0.09
20
187
30
315
0.95
0.06
1.6
1.6
4.24
5.17
u/l
2.01
21
273
37
386
0.96
0.06
1.3
1.4
—
—
—
0
0
22
207
1.06
0.06
1.5
1.4
52.14
215.56
nmol/24h
0.65
22
207
496
4921
1.01
0.06
7.3
6.7
5.15
5.09
kpa
0.68
480
4724
32
306
1.05
0.05
1.1
1.1
—
—
—
0
0
40
385
1.04
0.05
1.3
1.1
41.40
34.97
mg/l
0.40
35
330
94
960
0.98
0.05
2.7
2.9
8.11
8.25
kpa
0.36
94
944
36
374
0.96
0.05
1.2
1.1
358.42
226.04
mg/l
0.55
31
334
31
323
0.96
0.05
1.1
1.1
1.04
1.05
ratio
0.12
25
252
1110
11057
1.00
0.04
4.2
4.6
—
—
—
0
0
151
1531
0.99
0.04
2.0
2.0
375.06
629.62
ug/l
0.74
143
1428
13
140
0.93
0.04
1.2
2.1
1.27
2.19
ug/l
—
6
78
33
318
1.04
0.04
2.8
3.4
22.59
25.79
mu/l
0.23
33
303
416
4188
0.99
0.04
4.2
4.2
0.67
0.67
%
0.00
115
1172
149
1471
1.01
0.04
1.6
1.8
—
—
—
0
0
76
775
0.98
0.04
1.1
1.1
—
—
—
0
0
161
1591
1.01
0.04
1.6
1.7
—
—
—
0
0
40
412
0.97
0.03
1.5
1.5
183416.00
106668.06
e6/l
0.24
28
264
15
141
1.06
0.03
2.7
3.3
57.33
127.63
ng/l
—
6
49
386
3838
1.01
0.03
1.3
1.3
—
—
—
0
0
1038
10409
1.00
0.03
1.7
1.7
90736808.87
31361197.27
pmol/l
1.32
842
8635
20
191
1.05
0.03
1.3
1.6
—
—
—
0
0
429
4311
0.99
0.03
7.6
7.0
95.71
95.75
%
0.05
423
4160
161
1595
1.01
0.03
1.6
1.7
—
—
—
0
0
92
932
0.99
0.02
1.5
1.7
—
—
—
0
0
38
389
0.98
0.02
1.2
1.6
—
—
—
0
0
70
710
0.99
0.02
1.2
1.3
304.55
362.33
pmol/l
0.58
64
611
22
228
0.96
0.02
1.4
1.3
128.68
127.31
nmol/l
0.06
22
228
59
581
1.02
0.02
2.5
1.9
0.95
0.90
%
0.31
31
362
13
137
0.95
0.01
1.6
2.0
—
—
—
0
0
97
961
1.01
0.01
4.4
3.2
346.81
788.43
u/ml
0.64
86
859
22
227
0.97
0.01
1.1
1.3
9.32
10.99
mm/h
0.41
22
227
75
742
1.01
0.01
1.2
1.2
—
—
—
0
0
276
2770
1.00
0.01
1.9
1.8
—
—
—
0
0
52
513
1.01
0.01
1.6
2.2
0.63
0.97
g/24h
0.56
29
281
83
823
1.01
0.01
2.8
3.0
90.01
90.62
%
0.35
83
808
10
94
1.06
0.01
1.0
1.0
—
—
—
0
0
1442
14430
1.00
0.00
4.6
4.5
0.01
0.00
estimate
0.34
502
5179
161
1603
1.00
0.00
1.6
1.7
—
—
—
0
0
51
516
0.99
0.00
1.2
1.4
31.46
32.82
g/l
0.36
45
471
138
1374
1.00
0.00
2.6
2.8
26.31
25.12
mmol/l
2.53
138
1356
10
98
1.02
0.00
1.7
1.1
—
—
—
0
0
10
95
1.05
0.00
1.9
1.8
—
—
—
0
0
22
222
0.99
0.00
1.3
1.6
0.40
4.33
%
—
5
45
13
135
0.96
0.00
1.4
1.5
—
—
—
0
0
15
146
1.03
0.00
1.3
1.2
26.27
28.12
s
1.24
15
146
15
146
1.03
0.00
3.6
3.3
—
—
—
0
0
18
184
0.98
0.00
1.1
1.2
7.51
7.42
ph
1.69
12
117
45
446
1.01
0.00
1.2
1.4
1.57
1.47
nmol/l
0.07
36
373
45
454
0.99
0.00
1.2
1.4
4358.86
2113.59
e6/l
0.40
29
312
56
556
1.01
0.00
1.3
1.4
—
—
—
0
0
56
556
1.01
0.00
1.6
1.6
51.42
54.55
%
0.23
40
329
56
556
1.01
0.00
1.3
1.4
—
—
—
0
0
56
556
1.01
0.00
1.3
1.4
—
—
—
0
0
56
556
1.01
0.00
1.3
1.4
—
—
—
0
0
34
337
1.01
0.00
1.8
1.8
12.21
15.02
%
1.52
34
326
114
1136
1.00
0.00
1.7
2.2
—
—
—
0
0
15
149
1.01
0.00
2.3
1.7
9.04
9.07
ug/l
0.01
15
149
39
391
1.00
0.00
1.3
1.6
37.81
36.04
%
0.10
25
218
45
451
1.00
0.00
1.1
1.2
—
—
—
0
0
59
589
1.00
0.00
1.5
1.4
278.86
275.33
mosm/kgh2o
0.57
43
443
0
8
0.00
0.00
0.0
6.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
1.76
—
0
8
0
8
0.00
0.00
0.0
1.0
—
6927.63
—
0
8
0
8
0.00
0.00
0.0
1.0
—
0.03
—
0
8
5
49
1.02
-0.00
1.2
1.2
1.67
1.53
umol/24h
—
5
49
108
1080
1.00
-0.00
1.1
1.1
1.50
1.87
u/ml
0.19
54
556
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
57
0.88
-0.00
1.4
1.2
5.90
5.90
mmol/l
—
5
57
7
74
0.95
-0.00
1.0
1.5
33.57
21.58
%
—
7
64
158
1580
1.00
-0.00
1.6
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
87
0.92
-0.00
1.4
1.2
—
—
—
0
0
9
90
1.00
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
1205.00
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
7
77
0.91
-0.00
1.3
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_BREAST and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_BREAST 1.045 [0.95, 1.15] 0.36
Birth year 0.999 [0.99, 1.01] 0.807

During the follow-up period (1.1.1998 — 31.12.2019), 1574 out of 17928 females with CD2_BENIGN_BREAST died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_BREAST.

N-year risk Females Males
1 0.102% No data
5 0.61% No data
10 1.804% No data
15 3.457% No data
20 6.259% No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_BREAST – Benign neoplasm of breast

GWS hits: 5

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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