Granulomatosis with Polyangiitis: A small-vessel necrotizing vasculitis characterised by the association of inflammation of the vessel wall and peri- and extravascular granulomatosis.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
611 |
4. Check minimum number of eventsNone |
611 |
5. Include endpointsNone |
611 |
6. Filter based on genotype QC (FinnGen only) |
555 |
Control definitions (FinnGen only)
- Control exclude
- M13_SYSTCONNECT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M31
- Name in latin
- Granulomatosis Wegener
Similar endpoints
↥List of similar endpoints to
Wegener granulomatosis
based on the number of shared cases.
Similar with more cases:
- Other necrotizing vasculopathies (FG)
- Other necrotizing vasculopathies
- Systemic connective tissue disorders
- Autoimmune diseases related-to ILD
- Autoimmune diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2962 | 1497 | 1441 |
| Only index persons | 2449 | 1266 | 1183 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.04 |
| Only index persons | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 60.38 | 61.29 | 59.32 |
| Only index persons | 59.11 | 60.06 | 58.09 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 555 | 292 | 263 |
| Unadjusted period prevalence (%) | 0.11 | 0.10 | 0.12 |
| Median age at first event (years) | 56.60 | 55.06 | 58.31 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 576
- Matched controls
- 5760
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
34.1
307.7
376
301
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
307.7
499
*
L04AX01
ATC
azathioprine; systemic
66.0
307.7
293
89
L04AA06
ATC
mycophenolic acid; systemic
64.2
268.8
152
32
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
21.6
245.3
211
150
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
231.3
206
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
73.9
216.0
118
20
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
198.8
179
*
DHA10
NOMESCO Finland
Biopsy of cavity of nose
65.0
167.0
93
17
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
12.8
154.5
176
192
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
9.7
151.4
428
1319
M05BA04
ATC
alendronic acid; oral
11.3
146.0
184
230
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
14.6
133.1
132
115
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
12.9
131.4
143
144
L04AX03
ATC
methotrexate; systemic
9.0
120.6
183
284
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
24.2
117.7
87
42
H02AB06
ATC
prednisolone; systemic
9.9
116.0
485
2018
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
21.0
111.9
88
49
UDH02
NOMESCO Finland
Rhinopharyngoscopy
9.2
106.1
151
215
TGC00
NOMESCO Finland
Bronchial lavation
15.6
104.9
97
74
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
34.2
98.9
64
21
ZX120
NOMESCO Finland
Intravenous
7.7
98.6
169
296
Z94.0
ICD-10 Finland
Kidney transplant status
38.7
89.9
56
16
L01AA01
ATC
cyclophosphamide; systemic
262.5
89.2
89
*
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
84.5
79
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
15.1
84.3
78
59
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.4
83.2
455
2142
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
11.7
82.7
91
91
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.2
80.0
138
240
A11CC03
ATC
alfacalcidol; systemic
14.6
74.6
70
54
A12AA04
ATC
calcium carbonate; oral
20.0
73.4
58
32
H02AB04
ATC
methylprednisolone; systemic
5.3
71.1
188
485
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
68.1
64
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
5.6
64.5
147
331
N18.8
ICD-10 Finland
Other chronic renal failure
14.2
61.4
58
45
N18.0
ICD-10 Finland
End-stage renal disease
29.4
60.7
41
15
TK800
NOMESCO Finland
Hemodialysis
14.7
60.4
56
42
H65.2
ICD-10 Finland
Chronic serous otitis media
17.6
59.7
50
31
127
Kela drug reimbursment
Transplant complication
17.8
58.8
49
30
GD1AD
NOMESCO Finland
Thorax CT examination
6.4
58.4
110
206
R50.9
ICD-10 Finland
Fever, unspecified
4.5
57.7
182
532
Z49.1
ICD-10 Finland
Extracorporeal dialysis
20.6
56.8
44
23
B03XA02
ATC
darbepoetin alfa; parenteral
13.8
55.3
53
42
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
7.0
55.1
92
152
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
11.8
54.8
58
54
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.5
53.0
162
459
1XC02, ,
NOMESCO Finland
72.8
52.3
59
9
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
9.6
50.9
63
73
L01BA01
ATC
methotrexate; systemic
9.8
50.2
61
69
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
20.7
48.0
37
19
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
+∞
46.5
44
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
7.5
45.5
69
102
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
12.4
44.3
45
39
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.3
44.1
135
379
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
43.3
41
*
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
8.2
42.8
60
81
J31.0
ICD-10 Finland
Chronic rhinitis
4.7
42.0
110
273
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.3
41.9
241
1026
L04AD01
ATC
ciclosporin; systemic
13.4
41.3
40
32
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
5.5
41.3
87
179
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
7.6
41.0
61
88
M31.7
ICD-10 Finland
Microscopic polyangiitis
+∞
40.1
38
*
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
39.0
37
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
9.4
38.0
47
54
TPH04
NOMESCO Finland
Cathetrisation of vein
3.2
37.3
206
847
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
197.3
36.2
37
*
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
35.8
34
*
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
+∞
33.7
32
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.1
33.2
102
284
M35.3
ICD-10 Finland
Polymyalgia rheumatica
9.9
33.0
39
42
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.9
32.9
79
181
UDM02
NOMESCO Finland
Sinoscopy
8.2
32.7
45
59
H02AB07
ATC
prednisone; oral
3.6
32.5
129
428
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.0
32.5
75
166
J34.8
ICD-10 Finland
Other specified disorders of nose and nasal sinuses
11.6
31.4
33
30
WW200
NOMESCO Finland
Immunization
8.2
30.5
42
55
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
30.5
29
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
61.9
30.4
35
6
Z2446
NOMESCO Finland
Social worker
4.6
30.3
79
193
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.4
29.8
63
129
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
33.8
29.4
38
12
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
4.1
28.9
88
242
N08.5*M31.0
ICD-10 Finland
Glomerular disorders in Goodpasture's syndrome
+∞
28.4
27
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
56.3
27.5
32
6
WW400
NOMESCO Finland
Plasmaferesis
+∞
27.3
26
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.0
27.1
153
622
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
9.4
27.1
33
37
C03CA01
ATC
furosemide; systemic
2.6
26.6
236
1210
J01MA14
ATC
moxifloxacin; systemic
3.7
26.3
96
299
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.4
26.2
54
108
J01MA12
ATC
levofloxacin; systemic
2.9
25.8
157
664
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
8.3
25.4
34
43
A02BC02
ATC
pantoprazole; systemic
2.9
25.3
452
3202
4464A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Wegener's granulomatosis
+∞
25.2
24
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.6
24.6
62
147
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.3
24.6
69
178
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
50.7
24.5
29
6
ZX108
NOMESCO Finland
Inhalation
28.1
23.8
32
12
137
Kela drug reimbursment
Uraemia requiring dialysis
29.7
23.4
31
11
1AA01, ,
NOMESCO Finland
239.1
22.8
23
*
RD210, ,
NOMESCO Finland
9.1
22.6
28
32
Z49.2
ICD-10 Finland
Other dialysis
47.1
22.5
27
6
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.5
22.4
184
896
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.0
21.9
67
184
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
7.5
21.8
32
45
M13.9
ICD-10 Finland
Arthritis, unspecified
3.7
21.6
73
215
Z49.0
ICD-10 Finland
Preparatory care for dialysis
21.8
21.5
31
15
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
21.0
20
*
WX892
NOMESCO Finland
Monitored bed care
3.5
20.5
76
238
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.4
20.4
81
265
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
7.1
20.2
31
46
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.3
20.1
352
2348
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
21.7
20.1
29
14
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
7.9
20.1
28
37
N08.5*M30.0
ICD-10 Finland
Glomerular disorders in polyarteritis nodosa
+∞
19.9
19
*
Z3231
NOMESCO Finland
Registered nurse
2.3
19.7
201
1070
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
108.8
19.7
21
*
Z2221
NOMESCO Finland
Medical doctor
2.4
19.6
196
1035
L88
ICPC
Rheumatoid/seropositive arthritis
5.0
19.5
43
91
H65.0
ICD-10 Finland
Acute serous otitis media
8.2
19.3
26
33
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.0
19.3
99
377
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.7
19.3
64
186
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
15.5
19.1
31
21
P01BA02
ATC
hydroxychloroquine; oral
3.6
19.0
67
203
V03AE02
ATC
sevelamer; oral
72.4
18.8
21
*
R04.2
ICD-10 Finland
Haemoptysis
5.3
18.8
39
78
M05BB03
ATC
alendronic acid and colecalciferol; oral
6.2
18.4
32
54
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
5.9
18.4
34
61
R04.0
ICD-10 Finland
Epistaxis
3.3
18.4
74
244
M05BA07
ATC
risedronic acid; oral
5.4
17.9
36
70
C08CA01
ATC
amlodipine; oral
2.2
17.9
267
1647
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
+∞
17.8
17
*
N085, M318,
ICD-10 Finland
+∞
17.8
17
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.4
17.4
35
68
Z3229
NOMESCO Finland
Other healthcare associate professional
3.2
17.2
75
259
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.1
17.1
37
77
ZXA10
NOMESCO Finland
Bilateral
2.4
17.0
140
672
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.2
16.9
192
1058
M30.0
ICD-10 Finland
Polyarteritis nodosa
+∞
16.7
16
*
L04AD02
ATC
tacrolimus; systemic
14.0
16.6
28
21
PAW37
NOMESCO Finland
Biopsy of temporal artery
174.9
16.6
17
*
B07.9
ICD-10 Finland
Verruca simplex
4.7
16.4
39
88
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.7
16.3
54
156
H02AB09
ATC
hydrocortisone; systemic
6.1
16.3
29
50
B05DA
ATC
Isotonic solutions
25.3
16.1
22
9
A02BC01
ATC
omeprazole; systemic
2.2
16.0
189
1055
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.2
16.0
67
226
XG410
NOMESCO Finland
Flow-volume spirometry
4.2
15.8
43
108
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
5.8
15.7
29
52
J01FF01
ATC
clindamycin; systemic
2.2
15.7
184
1023
B03XA01
ATC
erythropoietin; parenteral
14.5
15.1
25
18
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.9
15.1
34
73
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
14.6
14
*
RS221, ,
NOMESCO Finland
10.8
14.4
27
26
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
14.3
175
982
A41.9
ICD-10 Finland
Sepsis, unspecified
4.3
14.1
37
90
R01AD08
ATC
fluticasone; nasal
2.1
14.1
189
1098
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.9
14.0
42
113
H26.3
ICD-10 Finland
Drug-induced cataract
18.1
13.9
21
12
H04.10
ICD-10 Finland
Dry eye syndrome
2.6
13.8
88
372
L04AA01
ATC
[U] ciclosporin
14.0
13.8
23
17
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
13.7
131
665
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.2
13.7
133
680
Z3226
NOMESCO Finland
Physiotherapist
2.2
13.6
131
668
ZXE00
NOMESCO Finland
One hour or less
2.0
13.4
246
1591
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.8
13.3
41
113
V03AE01
ATC
polystyrene sulfonate; oral
11.3
13.1
24
22
J01MA02
ATC
ciprofloxacin; systemic
1.9
13.0
245
1595
B05DB
ATC
Hypertonic solutions
23.2
13.0
18
8
A10AC01
ATC
insulin (human); parenteral
2.9
12.9
66
249
3AC01, ,
NOMESCO Finland
17.8
12.6
19
11
205
Kela drug reimbursment
Chronic hypertension
2.0
12.5
170
985
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
+∞
12.5
12
*
UDC00
NOMESCO Finland
Ear microscopy
2.8
12.5
65
247
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
24.9
12.5
17
7
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
12.5
226
1447
J05AB11
ATC
valaciclovir; oral
2.3
12.4
109
533
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
12.4
79
334
TK810
NOMESCO Finland
Hemofiltration
21.8
12.1
17
8
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
11.8
72
297
C09AA02
ATC
enalapril; systemic
2.1
11.8
133
717
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
11.8
61
231
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.5
11.8
82
361
TK820
NOMESCO Finland
Peritoneal dialysis
23.5
11.6
16
7
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
11.4
11.6
21
19
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
4.7
11.5
27
60
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
11.5
11
*
WX002
NOMESCO Finland
Sedation and analgesia
2.1
11.4
131
711
R4110
NOMESCO Finland
Physiotherapy
1.9
11.4
182
1112
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
11.3
255
1736
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
35.8
11.3
14
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.9
11.3
25
53
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
17.5
11.3
17
10
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
4.4
11.1
28
66
A12AA12
ATC
[U] calcium acetate
44.2
11.0
13
*
N25.0
ICD-10 Finland
Renal osteodystrophy
44.2
11.0
13
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.5
10.9
73
315
J01CA04
ATC
amoxicillin; systemic
2.1
10.8
479
4015
196
Kela drug reimbursment
Paricalcitol and cinacalcet
21.9
10.7
15
7
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
21.9
10.7
15
7
1CX01, ,
NOMESCO Finland
61.2
10.7
12
*
RS222, ,
NOMESCO Finland
11.5
10.6
19
17
DC1AD
NOMESCO Finland
Temporalbone CT
10.3
10.6
20
20
J05AB01
ATC
aciclovir; systemic
2.0
10.5
142
815
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
112.0
10.5
11
*
ZXD05
NOMESCO Finland
Urgent procedure
1.9
10.3
189
1199
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
19.2
10.3
15
8
R01AD12
ATC
fluticasone furoate; nasal
1.9
10.1
183
1157
M81.4
ICD-10 Finland
Drug-induced osteoporosis
20.5
9.8
14
7
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
20.5
9.8
14
7
321
Kela drug reimbursment
Paricalcitol and cinacalcet
13.7
9.7
16
12
J01DB01
ATC
cefalexin; oral
2.1
9.7
483
4111
JN4AD
NOMESCO Finland
Body CT examination
2.3
9.6
82
394
R4190
NOMESCO Finland
Nutritional therapy
3.4
9.6
34
103
N19
ICD-10 Finland
Unspecified kidney failure
3.4
9.5
35
109
6BA02, ,
NOMESCO Finland
30.6
9.4
12
*
M31.2
ICD-10 Finland
Lethal midline granuloma
+∞
9.4
9
*
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
5.0
9.4
20
41
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.5
9.4
64
279
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
9.3
72
332
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
9.3
92
470
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
9.3
9.1
18
20
DFF00
NOMESCO Finland
Pure tone audiometry
2.3
9.1
75
356
H66.9
ICD-10 Finland
Otitis media, unspecified
2.8
9.0
47
179
B02.9
ICD-10 Finland
Zoster without complication
2.6
9.0
53
215
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
8.9
249
1773
K65.0
ICD-10 Finland
Acute peritonitis
9.7
8.8
17
18
EB1WA, ,
NOMESCO Finland
14.3
8.7
14
10
M05BA06
ATC
ibandronic acid; systemic
4.9
8.6
19
40
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
16.6
8.6
13
8
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
8.6
124
725
CCD50
NOMESCO Finland
Dacryocystorhinostomy with insertion of tube
20.4
8.5
12
6
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
4.4
8.5
21
49
ZXA00
NOMESCO Finland
Right side
1.8
8.5
162
1033
J01AA02
ATC
doxycycline; systemic
1.8
8.5
441
3697
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
91.3
8.4
9
*
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.9
8.4
40
145
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.5
8.3
28
82
RS220, ,
NOMESCO Finland
9.6
8.3
16
17
C02CA01
ATC
prazosin; oral
7.0
8.1
19
28
V03AE03
ATC
lanthanum carbonate; oral
17.5
8.1
12
7
DM1DG
NOMESCO Finland
Paranasal sinuses and face area very extensive MRI examination with high intensity magnet
33.9
8.1
10
*
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.7
8.1
25
69
J32.4
ICD-10 Finland
Chronic pansinusitis
6.4
8.1
20
32
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
22.4
8.0
11
5
TAB00
NOMESCO Finland
Lumbar puncture
2.9
8.0
37
132
C08CA13
ATC
lercanidipine; oral
2.0
7.9
94
513
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
7.9
87
462
R01AD09
ATC
mometasone; nasal
1.7
7.9
260
1916
XX9XE
NOMESCO Finland
Other ultrasound examination
9.6
7.8
15
16
A03
ICPC
Fever
1.9
7.8
102
575
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.4
7.7
27
81
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
15.3
7.7
12
8
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
15.3
7.7
12
8
ZXA05
NOMESCO Finland
Left side
1.8
7.7
147
932
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
45.6
7.7
9
*
I77.6
ICD-10 Finland
Arteritis, unspecified
45.6
7.7
9
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.3
7.6
28
87
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
25.4
7.6
10
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
25.4
7.6
10
*
A07AA02
ATC
nystatin; oral
2.6
7.5
43
172
C02AC05
ATC
moxonidine; oral
2.9
7.5
35
126
5AB14, ,
NOMESCO Finland
81.1
7.4
8
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
7.4
274
2066
B01AB04
ATC
dalteparin; parenteral
2.8
7.4
37
138
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.5
7.3
25
74
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.0
7.3
91
504
DC1BD
NOMESCO Finland
Temporal bone extensive CT
+∞
7.3
7
*
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
+∞
7.3
7
*
DJA10
NOMESCO Finland
Biopsy of septum of nose
+∞
7.3
7
*
ZX100
NOMESCO Finland
Oral
6.4
7.3
18
29
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
16.0
7.2
11
7
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.4
7.2
42
914
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
7.4
7.2
16
22
J47
ICD-10 Finland
Bronchiectasis
4.0
7.2
20
51
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
30.4
7.2
9
*
H15.0
ICD-10 Finland
Scleritis
20.3
7.2
10
5
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
20.3
7.2
10
5
H15.1
ICD-10 Finland
Episcleritis
5.7
7.1
19
34
H05BX01
ATC
cinacalcet; oral
10.2
7.1
13
13
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
7.1
7.0
16
23
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
6.5
7.0
17
27
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
6.9
211
1511
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.5
6.9
42
173
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.5
6.9
23
67
B01AA03
ATC
warfarin; systemic
1.8
6.9
109
653
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
6.8
169
1148
3025
Kela drug reimbursment
Calcium carbonate
11.1
6.8
12
11
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.5
6.8
44
187
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
40.5
6.8
8
*
K06.18
ICD-10 Finland
Another gingival hyperplasia
16.9
6.8
10
6
JN4BD
NOMESCO Finland
Extensive body CT
2.1
6.7
66
335
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.8
6.7
112
681
306
Kela drug reimbursment
Erythropoietin and darbepoetin
22.8
6.7
9
*
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
6.6
6.7
16
25
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
12.4
6.6
11
9
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
12.4
6.6
11
9
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.2
6.6
57
276
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
4.0
6.5
18
46
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.1
6.5
59
291
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
3.5
6.5
22
65
M01AE01
ATC
ibuprofen; systemic, rectal
0.6
6.4
411
4632
WW500
NOMESCO Finland
Blood transfusion
2.8
6.4
32
120
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
11.2
6.3
11
10
R80
ICD-10 Finland
Isolated proteinuria
11.2
6.3
11
10
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
11.2
6.3
11
10
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
6.3
105
638
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
18.3
6.3
9
5
N18.2
ICD-10 Finland
Chronic kidney disease, stage 2
18.3
6.3
9
5
44620
ICD-8 Finland
Polyarteritis nodosa and allied conditions, Other hypersensitivity angiitis
+∞
6.3
6
*
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
+∞
6.3
6
*
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
+∞
6.3
6
*
J38.6
ICD-10 Finland
Stenosis of larynx
27.0
6.2
8
*
SPAT1255
SPAT
Intravenous administration of medicine
2.4
6.2
41
176
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
4.0
6.2
17
43
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
5.4
6.2
17
32
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
7.8
6.1
13
17
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
2.9
6.1
29
105
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
12.7
6.1
10
8
M95.0
ICD-10 Finland
Acquired deformity of nose
12.7
6.1
10
8
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
12.7
6.1
10
8
H69.0
ICD-10 Finland
Patulous Eustachian tube
10.2
6.1
11
11
I15.0
ICD-10 Finland
Renovascular hypertension
10.2
6.1
11
11
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.1
6.0
61
313
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
6.1
6.0
15
25
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
5.6
6.0
16
29
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
6.0
144
966
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
190
80
34.95
278.23
4.0
1.1
167.50
—
titre
—
80
0
191
321
8.41
117.16
2.5
1.8
0.81
1.28
g/l
3.29
184
298
134
154
11.04
111.53
1.6
1.5
0.69
0.14
iu/ml
0.52
20
25
125
142
10.97
104.64
2.7
1.1
1.25
1.21
g/l
0.43
117
137
270
712
6.26
104.29
15.7
6.0
1.07
1.04
mmol/l
1.00
264
664
339
1169
5.62
94.17
8.7
2.7
3.03
5.74
e6/l
3.03
331
1069
106
111
11.48
93.65
6.8
7.4
615.14
359.93
iu/ml
0.38
14
15
118
168
8.58
81.94
4.3
1.3
14.92
4.28
iu/ml
1.40
34
35
179
409
5.90
78.39
10.1
3.8
115.48
88.85
ng/l
2.29
170
361
66
47
15.73
73.57
2.0
1.1
131.43
104.00
titre
—
14
5
383
1705
4.72
71.03
12.8
3.3
29.84
97.08
e6/l
1.01
356
1299
63
49
14.31
66.71
1.7
1.6
—
—
—
0
0
404
1938
4.63
65.99
15.9
3.9
44.38
103.04
e6/l
1.59
358
1360
228
762
4.30
60.79
4.9
2.5
22.10
22.67
%
0.26
223
720
493
2897
5.87
57.94
26.1
10.0
4.82
4.14
e9/l
6.54
474
2529
87
129
7.77
57.61
1.7
1.5
—
—
—
0
0
113
221
6.12
57.33
3.0
2.0
1.76
1.46
g/l
1.85
99
202
468
2666
5.03
56.61
10.9
3.8
0.00
0.00
estimate
-0.00
126
557
424
2251
4.35
56.58
4.4
2.5
80.84
77.24
nmol/l
2.16
418
2026
330
1485
3.86
56.20
13.0
3.2
0.11
0.50
e6/l
5.46
303
1088
230
821
4.00
55.08
4.7
2.4
2.12
2.30
g/l
5.28
224
764
430
2334
4.32
54.86
16.5
6.6
1.22
1.21
mmol/l
1.37
419
2153
81
117
7.89
54.80
1.6
1.4
—
—
—
0
0
469
2714
4.92
54.53
11.0
3.9
0.00
0.58
estimate
0.50
125
525
239
885
3.91
54.10
4.7
2.5
11.42
12.90
umol/l
2.68
234
826
467
2702
4.85
54.09
11.0
3.9
9.42
2.85
estimate
0.30
128
571
452
2583
4.48
52.52
20.1
7.4
1.22
1.21
mmol/l
1.05
405
2240
75
107
7.91
51.20
1.8
1.6
—
—
—
0
0
95
177
6.23
50.41
2.9
3.1
—
—
—
0
0
182
583
4.10
50.24
3.5
4.7
249.34
251.93
u/l
0.07
175
556
104
218
5.60
48.63
1.7
2.4
31.44
40.26
u/l
5.12
96
198
341
1733
3.37
44.74
11.1
3.4
74.03
54.92
mg/l
1.13
291
1138
226
909
3.45
43.44
2.5
1.9
—
—
—
0
0
187
677
3.61
42.28
2.2
1.8
—
—
—
0
0
78
142
6.20
42.15
2.0
1.7
—
—
—
0
0
342
1784
3.26
42.10
13.0
4.1
14.60
9.61
mg/mmol
1.62
289
1125
61
86
7.81
41.89
1.8
1.6
—
—
—
0
0
79
149
5.99
41.13
2.1
1.7
—
—
—
0
0
179
644
3.58
40.67
2.3
1.9
—
—
—
0
0
82
163
5.70
40.36
1.6
1.3
—
—
—
0
0
345
1851
3.15
39.65
11.4
3.3
7.06
7.76
mmol/l
2.52
328
1563
218
914
3.23
38.33
10.4
2.9
0.35
1.05
e6/l
8.57
164
473
50
66
8.20
36.22
2.0
1.8
—
—
—
0
0
63
109
6.37
35.69
1.8
1.5
—
—
—
0
0
229
1031
3.03
35.00
2.2
1.5
2.06
2.52
g/l
3.89
190
620
144
492
3.57
34.91
2.3
2.0
313.74
390.93
nmol/l
5.32
139
461
50
70
7.73
34.43
2.1
1.7
—
—
—
0
0
383
2287
3.01
34.42
30.2
11.6
0.01
0.00
e9/l
0.38
349
1865
57
93
6.69
34.15
2.2
2.0
—
—
—
0
0
147
532
3.37
32.33
9.5
3.7
1.65
1.81
mmol/l
0.24
140
454
69
145
5.27
31.74
1.8
2.4
10.20
12.06
mg/l
1.02
62
136
31
26
12.54
30.99
2.5
2.1
—
—
—
0
0
510
3731
4.20
29.95
18.3
4.1
14.81
11.81
mm/h
4.71
502
3473
33
35
9.94
28.20
2.0
1.6
—
—
—
0
0
30
29
10.86
27.33
2.1
1.7
—
—
—
0
0
188
852
2.79
27.26
11.4
3.0
1.35
2.29
e6/l
1.79
134
412
514
3862
4.07
27.12
22.6
8.5
72.83
80.06
u/l
5.87
509
3662
30
31
10.15
26.09
2.1
1.7
—
—
—
0
0
246
1322
2.50
24.72
4.8
2.9
355.70
350.30
umol/l
0.37
237
1172
186
877
2.66
24.57
4.1
3.6
0.81
0.82
mmol/l
0.46
180
837
52
107
5.24
24.38
1.5
1.2
37.00
3.56
u/ml
—
7
10
42
71
6.30
24.20
1.3
1.2
—
—
—
0
0
455
3293
2.82
23.32
9.4
4.7
11611.44
2352.76
e6/l
—
9
51
109
405
3.09
22.33
4.0
2.9
59.03
64.73
ml/min/173m2
0.72
59
181
46
95
5.18
21.45
2.0
1.4
97.00
146.42
au/ml
—
9
30
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
57
144
4.28
20.81
4.1
2.5
0.35
0.33
iu/ml
0.13
30
79
290
1771
2.28
20.79
4.6
3.4
2.33
2.36
mmol/l
1.81
282
1600
31
18
18.12
20.23
1.4
1.6
—
—
—
0
0
59
157
4.07
20.10
2.0
5.0
63.01
88.51
mg/l
0.27
49
128
59
157
4.07
20.10
2.0
5.0
46.83
44.88
mg/l
0.04
49
129
29
40
7.58
20.09
2.3
1.9
—
—
—
0
0
391
2735
2.34
19.82
7.9
7.1
10.07
11.72
umol/l
2.81
386
2615
72
226
3.50
19.31
2.6
1.9
3.02
2.64
ug/l
0.09
67
203
52
130
4.30
19.23
3.2
2.9
3.21
2.00
index
0.72
24
74
55
144
4.12
19.13
1.7
4.7
1.37
2.63
ratio
1.31
30
78
252
1493
2.22
18.98
11.7
3.9
0.00
0.01
estimate
0.78
122
523
93
345
3.02
18.95
1.6
1.3
151.66
281.56
u/ml
0.76
86
318
41
87
5.00
18.51
1.6
1.1
85.00
25.17
u/ml
—
5
8
227
1300
2.23
18.48
7.1
4.2
95.77
89.98
%
3.01
219
1279
45
104
4.61
18.36
4.8
2.9
12.00
9.21
pmol/l
0.66
45
104
32
56
5.99
17.77
1.1
1.1
—
—
—
0
0
44
105
4.45
17.24
1.4
1.4
302.72
281.47
u/ml
0.13
32
59
32
58
5.78
17.14
6.1
3.9
—
—
—
0
0
84
317
2.93
16.51
1.8
1.6
—
—
—
0
0
52
146
3.82
16.40
1.5
1.6
—
—
—
0
0
23
12
19.90
15.66
1.3
1.3
—
—
—
0
0
24
15
16.63
15.36
2.5
2.9
0.62
0.60
mmol/l
0.49
24
15
272
1766
2.02
15.14
4.3
3.5
27.59
33.63
u/l
2.88
263
1674
404
3033
2.11
14.86
8.8
5.3
6.59
6.72
mmol/l
0.56
396
2884
217
1336
2.00
13.70
2.9
2.2
2.93
2.92
mg/l
0.02
199
1153
241
1566
1.93
12.79
2.5
2.1
114.79
257.58
u/l
2.28
234
1478
90
400
2.48
12.72
6.7
3.9
1.22
1.23
mmol/l
0.23
85
346
26
54
5.00
12.01
2.1
2.2
—
—
—
0
0
189
1157
1.94
11.80
2.6
1.7
1.97
1.37
mg/l
1.26
163
916
326
2375
1.86
11.80
5.2
3.0
183.76
131.25
ug/l
2.34
319
2218
289
2032
1.85
11.68
11.1
3.8
0.00
0.03
estimate
1.47
117
471
74
312
2.57
11.65
6.8
3.6
1.43
1.90
mmol/l
0.57
57
235
105
519
2.25
11.61
3.6
3.4
—
—
—
0
0
86
390
2.42
11.59
1.6
1.6
—
—
—
0
0
41
125
3.45
11.44
1.7
1.6
—
—
—
0
0
21
38
5.70
11.24
1.4
1.1
—
—
—
0
0
21
38
5.70
11.24
1.4
1.1
—
—
—
0
0
26
58
4.65
11.06
2.1
2.2
—
—
—
0
0
224
1475
1.85
11.01
9.1
3.3
0.00
0.06
estimate
0.58
113
446
156
913
1.97
11.00
1.4
1.3
30.07
33.67
iu/ml
0.29
63
274
20
36
5.72
10.76
1.5
1.1
—
—
—
0
0
21
40
5.41
10.66
1.4
1.1
—
—
—
0
0
20
37
5.56
10.46
1.5
1.1
—
—
—
0
0
34
98
3.62
10.32
1.5
1.3
—
—
—
0
0
34
98
3.62
10.32
1.5
1.3
—
—
—
0
0
21
42
5.15
10.11
1.4
1.1
—
—
—
0
0
115
623
2.06
9.98
11.5
8.3
0.48
0.93
mmol/l
0.60
96
518
27
71
3.94
9.33
1.1
1.2
5.70
2.48
u/ml
—
10
23
27
71
3.94
9.33
1.1
1.2
2.86
3.60
u/ml
—
7
30
18
19
9.74
9.32
1.4
1.1
—
—
—
0
0
142
846
1.90
9.32
1.4
1.3
5.85
11.44
u/ml
0.91
58
308
322
2442
1.72
9.22
18.6
14.2
1.25
1.24
inr
0.06
270
2025
24
60
4.13
8.87
1.5
1.4
—
—
—
0
0
13
8
16.58
8.58
1.8
1.5
—
—
—
0
0
12
7
17.47
8.10
2.2
1.1
90.67
89.57
%
—
12
7
38
137
2.90
8.07
1.4
1.3
—
—
—
0
0
159
1032
1.75
7.71
3.0
2.9
2.47
2.45
mmol/l
1.01
149
928
17
38
4.58
7.22
1.4
1.3
—
—
—
0
0
17
27
6.45
6.98
4.4
3.0
0.71
0.81
index
0.31
17
27
64
318
2.14
6.89
2.5
2.4
22.04
18.47
au/ml
—
5
23
88
496
1.91
6.70
2.1
2.4
35.44
31.95
u/l
0.57
82
415
18
45
4.10
6.67
1.3
1.2
0.43
0.47
u/ml
—
10
23
13
15
8.84
6.58
1.2
1.0
—
—
—
0
0
15
23
6.66
6.37
2.9
5.4
—
—
—
0
0
532
4878
2.19
6.04
49.3
16.1
19.08
24.66
mg/l
6.60
513
4029
466
4108
1.70
5.90
53.5
20.3
14.14
13.64
%
14.40
466
4068
129
846
1.68
5.86
1.8
1.7
1161.55
1199.58
nmol/l
0.16
113
649
20
60
3.42
5.77
1.8
1.7
87.27
89.98
%
0.65
20
60
70
384
1.94
5.76
3.7
3.5
102.45
215.79
ng/l
3.57
65
352
16
31
5.28
5.74
1.0
1.0
—
—
—
0
0
24
82
3.01
5.64
8.8
6.1
13.41
11.19
mg/l
1.68
24
75
205
1522
1.54
5.50
1.9
1.7
17.87
20.52
nmol/l
2.06
193
1288
16
33
4.96
5.46
2.9
3.1
1.59
1.09
%
0.40
16
33
8
5
16.20
5.42
1.0
1.0
—
—
—
0
0
18
54
3.41
5.20
1.7
1.7
—
—
—
0
0
18
54
3.41
5.20
1.7
1.7
—
—
—
0
0
18
54
3.41
5.20
1.7
1.7
—
—
—
0
0
14
27
5.29
5.11
1.2
1.1
0.82
0.51
ratio
—
9
14
33
142
2.40
5.01
1.7
1.2
—
—
—
0
0
28
113
2.55
4.87
1.4
1.2
381.65
12.96
e6/l
0.48
23
85
31
132
2.43
4.82
1.4
1.3
746.42
488.34
mg/l
0.58
31
126
8
7
11.57
4.79
1.0
1.0
—
—
—
0
0
13
27
4.90
4.52
1.1
1.1
—
—
—
0
0
21
77
2.79
4.39
1.2
1.4
—
—
—
0
0
9
12
7.60
4.37
1.4
1.5
—
—
—
0
0
20
72
2.84
4.32
2.5
2.3
31.70
32.92
pg
0.52
20
72
207
1609
1.45
4.20
3.5
3.2
1658.99
1261.43
ng/l
0.64
189
1379
30
135
2.29
4.16
3.7
2.1
121.95
129.39
g/l
0.81
21
108
291
2410
1.42
4.15
3.7
2.8
—
—
estimate
—
0
0
70
426
1.73
4.15
1.7
1.5
—
—
—
0
0
207
1621
1.43
4.00
2.8
2.7
169.40
62.11
u/l
0.51
202
1510
142
1042
1.48
3.83
4.6
4.2
182.14
353.01
ng/l
1.04
122
827
167
1270
1.44
3.74
3.8
2.4
—
—
—
0
0
510
4741
1.66
3.71
40.3
15.7
71.00
80.73
ml/min/173m2
13.34
501
4403
10
20
5.07
3.70
1.0
1.3
—
—
—
0
0
156
1186
1.43
3.47
11.5
4.0
1.02
1.02
kg/l
0.99
127
783
11
27
4.13
3.41
1.7
2.0
—
—
—
0
0
11
27
4.13
3.41
1.7
2.0
—
—
—
0
0
11
27
4.13
3.41
1.7
2.0
—
—
—
0
0
11
27
4.13
3.41
1.7
2.0
—
—
—
0
0
29
141
2.11
3.38
2.4
1.5
13081.58
16578.04
e6/l
0.17
24
101
49
286
1.78
3.37
1.5
1.4
—
—
—
0
0
272
2287
1.36
3.27
2.3
2.1
95.24
96.16
pmol/l
0.13
161
1206
29
148
2.01
3.00
1.4
1.4
166.24
226.13
miu/ml
—
7
70
10
26
3.89
2.99
1.2
1.3
—
—
—
0
0
10
26
3.89
2.99
1.2
1.3
—
—
—
0
0
24
114
2.15
2.98
2.7
1.5
—
—
—
0
0
86
603
1.50
2.88
2.8
3.2
6.88
9.37
umol/l
0.98
76
541
7
13
5.44
2.87
1.1
1.0
—
—
—
0
0
13
47
2.81
2.83
4.3
2.3
—
—
—
0
0
15
59
2.58
2.80
1.5
1.2
—
—
—
0
0
35
200
1.80
2.62
2.4
1.9
—
—
—
0
0
8
20
4.04
2.57
2.0
2.2
—
—
—
0
0
8
20
4.04
2.57
1.0
1.1
—
—
—
0
0
8
20
4.04
2.57
2.0
2.2
—
—
—
0
0
8
20
4.04
2.57
2.0
2.2
—
—
—
0
0
30
509
0.57
2.43
1.2
2.0
3.04
3.55
ratio
1.50
17
411
238
2026
1.30
2.41
4.7
3.8
48.37
88.23
ng/l
0.50
191
1470
7
17
4.15
2.36
1.1
1.0
1582.71
1277.41
miu/ml
—
7
17
8
23
3.51
2.27
3.3
1.6
127.25
114.41
ng/l
—
8
23
6
13
4.65
2.27
2.2
1.1
—
—
—
0
0
7
18
3.92
2.26
8.6
3.8
4.56
5.02
kpa
—
7
18
7
18
3.92
2.26
8.6
3.8
11.34
10.39
kpa
—
7
18
20
372
0.52
2.22
1.2
1.7
3.32
3.53
mmol/l
—
9
276
6
14
4.32
2.15
1.2
1.0
—
—
—
0
0
9
30
3.03
2.15
1.1
1.3
—
—
—
0
0
10
36
2.81
2.14
1.3
1.2
—
—
—
0
0
5
10
5.03
2.07
1.0
1.0
—
—
—
0
0
5
11
4.57
1.94
1.0
1.3
—
—
—
0
0
11
45
2.47
1.94
1.0
1.1
113.27
104.27
pmol/l
0.20
11
45
6
16
3.78
1.94
2.2
1.1
—
—
—
0
0
7
22
3.21
1.88
1.6
1.2
—
—
—
0
0
28
167
1.71
1.87
1.5
1.3
—
—
—
0
0
5
12
4.19
1.82
1.0
1.3
—
—
—
0
0
15
73
2.08
1.82
1.0
1.1
—
—
—
0
0
7
23
3.07
1.80
1.4
1.1
414.29
191.93
iu/ml
—
7
23
8
29
2.78
1.79
1.0
1.1
—
—
—
0
0
331
3005
1.24
1.77
3.4
3.0
—
—
—
0
0
129
1052
1.29
1.75
1.6
1.7
91525841.57
13280798.99
pmol/l
0.59
118
881
6
18
3.36
1.75
1.8
2.4
39.93
41.94
g/l
—
6
18
8
30
2.69
1.73
2.3
3.9
124.75
94.33
%
—
8
30
5
13
3.87
1.72
1.0
1.3
—
—
—
0
0
30
188
1.63
1.69
2.1
1.8
—
—
—
0
0
12
56
2.17
1.62
1.0
1.1
—
—
—
0
0
246
2181
1.22
1.59
2.5
1.9
1.40
1.36
mmol/l
0.34
222
1850
488
4657
1.31
1.57
8.1
6.6
39.36
39.46
mmol/mol
0.05
479
4378
10
45
2.24
1.47
1.2
1.0
—
—
—
0
0
48
651
0.71
1.45
1.4
1.7
1.57
1.49
%
0.29
41
577
5
17
2.96
1.36
1.0
1.3
—
—
—
0
0
24
152
1.60
1.34
1.3
1.1
—
—
—
0
0
11
54
2.06
1.33
1.0
1.1
—
—
—
0
0
8
36
2.24
1.24
1.1
1.5
78.38
75.56
umol/l
—
8
36
23
148
1.58
1.22
1.3
1.4
—
—
—
0
0
15
249
0.59
1.20
1.0
1.0
—
—
—
0
0
458
4757
0.82
1.13
6.2
5.2
5.79
6.00
mmol/l
2.63
438
4386
8
40
2.01
1.12
2.0
1.9
—
—
—
0
0
54
418
1.32
1.11
2.1
2.4
4.75
6.84
ug/l
0.67
44
376
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
31
2.27
1.10
1.0
1.2
—
—
—
0
0
25
169
1.50
1.09
2.3
1.7
—
—
—
0
0
38
507
0.73
1.07
1.6
2.1
—
—
—
0
0
27
187
1.47
1.05
6.3
4.0
1.25
1.38
mmol/l
0.52
27
182
9
46
1.97
1.04
1.1
1.0
—
—
—
0
0
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
15
237
0.62
1.01
1.7
2.0
—
—
—
0
0
42
546
0.75
1.00
1.7
2.2
—
—
—
0
0
103
876
1.21
0.99
1.7
1.5
—
—
—
0
0
19
124
1.55
0.98
1.5
1.9
4.49
5.41
iu/l
—
8
45
7
36
1.96
0.97
2.0
1.3
—
—
—
0
0
7
36
1.96
0.97
2.0
1.3
—
—
—
0
0
22
151
1.48
0.91
1.2
1.1
—
—
—
0
0
89
1042
0.83
0.89
2.7
3.2
0.74
0.77
ug/l
0.15
67
671
37
471
0.77
0.79
2.2
2.4
12.56
13.69
nmol/l
0.35
32
429
0
27
0.00
0.77
0.0
1.3
—
—
—
0
0
12
183
0.65
0.73
2.3
1.9
57.83
40.47
nmol/l
1.59
12
177
5
26
1.93
0.70
1.2
1.5
1.40
1.61
u/field
—
5
17
124
1383
0.87
0.70
4.0
4.6
22.39
21.66
%
0.22
64
666
11
69
1.61
0.68
2.4
1.7
—
—
—
0
0
5
27
1.86
0.68
1.4
1.1
27.20
8.52
mm/h
—
5
27
5
27
1.86
0.68
1.6
1.2
—
—
—
0
0
5
27
1.86
0.68
1.6
1.2
—
—
—
0
0
5
91
0.55
0.67
2.0
1.7
—
—
—
0
0
18
247
0.72
0.65
1.4
1.6
0.27
0.34
mg/l
—
10
119
133
1204
1.14
0.62
1.2
1.3
0.62
1.18
u/ml
1.70
31
328
21
156
1.36
0.62
1.5
1.4
—
—
—
0
0
32
256
1.26
0.58
9.0
3.9
1.02
1.02
ratio
0.73
32
242
8
54
1.49
0.57
1.4
1.3
—
—
—
0
0
6
36
1.67
0.57
1.5
1.3
—
—
—
0
0
6
36
1.67
0.57
1.5
1.3
—
—
—
0
0
6
99
0.60
0.52
1.5
1.5
1.34
1.13
ratio
—
6
68
6
99
0.60
0.52
1.5
1.5
0.94
0.98
ratio
—
6
68
6
99
0.60
0.52
1.5
1.5
2.04
1.11
ratio
—
6
68
18
136
1.33
0.49
2.7
2.2
19878.80
6176.45
u/l
—
6
51
7
49
1.43
0.46
1.1
1.1
—
—
—
0
0
5
31
1.62
0.43
1.2
1.1
—
—
—
0
0
8
57
1.41
0.42
1.7
1.6
58.43
50.96
ug/l
—
8
57
352
3407
1.09
0.41
4.1
3.4
58.85
50.41
u/l
0.36
338
3213
14
105
1.34
0.41
4.4
4.1
26.89
30.90
mg/l
—
9
75
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
7
105
0.66
0.39
1.4
1.6
97.23
59.05
ug/l
—
7
91
50
566
0.87
0.38
12.8
6.9
—
—
—
0
0
62
688
0.89
0.35
1.5
1.5
—
—
—
0
0
5
80
0.62
0.35
1.0
1.1
—
21.67
—
0
15
536
5303
1.15
0.35
63.0
24.9
263.84
247.32
e9/l
6.36
531
5215
392
3829
1.07
0.33
4.7
4.3
15.11
14.82
pmol/l
1.51
366
3492
29
248
1.18
0.32
1.2
1.3
—
—
—
0
0
536
5307
1.14
0.32
62.9
24.8
4.34
4.50
e12/l
9.88
529
5206
536
5310
1.14
0.29
63.2
25.0
129.93
135.65
g/l
14.61
531
5258
17
140
1.22
0.27
1.2
1.3
—
—
—
0
0
5
72
0.69
0.26
1.0
1.3
7.64
7.28
mmol/l
—
5
61
9
73
1.24
0.25
1.0
1.1
1.70
1.49
g/l
—
9
68
20
172
1.17
0.22
1.2
1.2
0.80
0.90
g/l
1.43
20
172
25
283
0.88
0.21
1.8
2.1
—
—
—
0
0
167
1734
0.95
0.21
4.5
5.4
2.40
2.42
ug/l
0.02
151
1570
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
51
552
0.92
0.21
3.1
4.4
2.47
33.97
ug/l
1.42
41
464
0
13
0.00
0.21
0.0
1.1
—
0.30
—
0
13
19
164
1.16
0.20
1.1
1.1
1.48
1.51
g/l
0.28
19
164
11
133
0.82
0.19
1.4
1.4
—
—
—
0
0
8
70
1.14
0.16
2.0
1.5
—
—
—
0
0
8
70
1.14
0.16
2.0
1.5
—
—
—
0
0
8
70
1.14
0.16
2.0
1.5
—
—
—
0
0
58
616
0.94
0.16
4.6
5.1
32.75
31.57
%
0.43
48
407
12
140
0.85
0.15
7.4
3.4
1.49
1.59
mmol/l
0.13
12
135
9
82
1.10
0.15
1.4
1.6
—
—
—
0
0
35
325
1.08
0.13
1.5
1.2
210.96
153.73
u/ml
0.23
14
126
489
4859
1.04
0.11
6.1
5.2
4.61
4.59
mmol/l
0.14
471
4542
5
47
1.06
0.09
1.4
1.6
260.80
280.97
mu/l
—
5
39
5
62
0.80
0.08
3.8
2.8
5.04
5.86
umol/l
—
5
44
7
67
1.05
0.08
2.0
1.5
—
—
—
0
0
7
67
1.05
0.08
2.0
1.5
—
—
—
0
0
7
68
1.03
0.08
2.0
1.5
—
—
—
0
0
454
4562
0.98
0.06
5.7
5.3
1.97
1.92
mu/l
0.34
429
4214
492
4935
0.98
0.04
6.6
5.9
2.61
2.69
mmol/l
1.26
474
4595
461
4623
0.99
0.03
5.0
4.4
1.36
1.29
mmol/l
1.30
444
4261
483
4841
0.99
0.02
6.0
5.1
1.53
1.45
mmol/l
3.63
466
4499
19
186
1.02
0.00
1.6
1.6
6.96
7.73
u/ml
—
7
39
16
157
1.02
0.00
1.9
1.4
277.80
284.15
ug/g
—
10
91
0
9
0.00
0.00
0.0
1.1
—
1.18
—
0
9
7
71
0.99
-0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
9
92
0.98
-0.00
1.0
1.2
18.33
24.36
u/l
—
9
80
5
55
0.91
-0.00
1.4
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
40.60
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint M13_WEGENER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_WEGENER | 2.443 [2.07, 2.88] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.026 |
During the follow-up period (1.1.1998 — 31.12.2019), 351 out of 1165 females with M13_WEGENER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_WEGENER | 2.398 [2.01, 2.86] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 368 out of 1088 males with M13_WEGENER died.
Mortality risk
Mortality risk for people of age
years, who have M13_WEGENER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.245% | 0.406% |
| 5 | 1.471% | 2.311% |
| 10 | 3.471% | 6.235% |
| 15 | 6.26% | 11.394% |
| 20 | 10.164% | 18.006% |
Relationships between endpoints
↥Index endpoint: M13_WEGENER – Wegener granulomatosis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data