Crowding of teeth, including avohilmo

K11_CROWDI_TEETH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.30
  • Hospital discharge: ICD-10 K07.30
  • Cause of death: ICD-10 K07.30

3 out of 7 registries used, show all original rules.

5429

4. Check minimum number of events

None

5429

5. Include endpoints

None

5429

6. Filter based on genotype QC (FinnGen only)

4891

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 192545 104811 87635
Only index persons 155040 84820 70220
Unadjusted period prevalence (%)
Whole population 2.75 3.00 2.45
Only index persons 2.92 3.12 2.68
Median age at first event (years)
Whole population 10.29 10.33 10.22
Only index persons 11.12 11.18 11.04

-FinnGen-

Key figures

All Female Male
Number of individuals 4891 3472 1419
Unadjusted period prevalence (%) 1.06 1.23 0.65
Median age at first event (years) 16.66 17.43 14.77

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4586
Matched controls
37958
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
8.7
307.7
846
963
SXC05
NOMESCO Finland
Other oral or dental procedure
5.0
307.7
1437
3147
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
6.5
307.7
1069
1689
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
4.9
307.7
1599
3725
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
6.8
307.7
1303
2094
SAA04
NOMESCO Finland
Special examination of mouth
5.6
307.7
1051
1919
SJC10
NOMESCO Finland
Orthodontic band in one tooth
10.9
307.7
1171
1162
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
+∞
307.7
4586
*
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
10.9
307.7
1645
1857
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
5.7
307.7
1021
1808
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
6.3
307.7
1397
2453
K07.23
ICD-10 Finland
Deep bite
6.5
307.7
970
1511
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
7.1
307.7
1035
1501
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
7.0
307.7
697
952
SBB10
NOMESCO Finland
Dental impressions
8.4
307.7
2324
4130
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
7.8
307.7
1233
1715
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
7.6
307.7
733
927
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
10.1
307.7
1438
1644
EB1MA
NOMESCO Finland
Cephalometry with X-ray
7.9
307.7
1176
1594
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
9.9
307.7
1184
1292
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
9.7
307.7
1410
1669
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
10.3
307.7
1142
1188
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
9.2
307.7
858
930
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
11.1
307.7
1626
1796
K07.13
ICD-10 Finland
Retrognaty, mandibular
12.3
307.7
563
428
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
4.5
307.5
922
1997
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
5.1
297.9
754
1415
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
23.8
284.9
235
86
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
4.3
271.4
862
1941
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
6.2
270.8
532
783
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
4.8
269.7
722
1416
OIKH, ,
NOMESCO Finland
4.4
267.1
813
1770
OIKK, ,
NOMESCO Finland
3.8
263.6
1030
2695
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
6.9
238.9
422
553
K07.24
ICD-10 Finland
Open bite
7.1
220.3
377
476
SAA03
NOMESCO Finland
Extended examination of mouth
2.7
210.0
3147
16866
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.6
203.0
2810
14384
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
7.5
184.2
297
349
OIKAL, ,
NOMESCO Finland
5.3
174.2
394
658
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
10.6
166.3
204
166
OIKVA, ,
NOMESCO Finland
3.9
154.8
518
1189
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
3.2
132.7
611
1728
OIKKK, ,
NOMESCO Finland
17.0
129.8
122
61
K07.14
ICD-10 Finland
Retrognaty, maxillary
10.2
123.7
155
130
EBA00
NOMESCO Finland
Extraction of tooth
2.1
121.4
2489
13816
OIKRE, ,
NOMESCO Finland
6.9
121.0
205
254
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
6.6
119.1
210
272
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
5.7
118.8
245
373
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
17.7
118.4
109
52
SAALT, ,
NOMESCO Finland
4.2
114.9
346
730
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
114.3
2322
12745
WZA90
NOMESCO Finland
Other medical or dental certificate
2.1
112.9
1659
8080
EEC05
NOMESCO Finland
Le Fort I osteotomy
15.6
107.4
105
57
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
4.0
106.2
342
758
SJC20
NOMESCO Finland
Extraoral traction appliance arrangement incl. patient instructions
7.2
102.8
169
202
SJB30
NOMESCO Finland
Extraoral traction arrangements and operation instruction, removable appliance
4.7
95.3
242
444
SAA02
NOMESCO Finland
Basic examination of mouth
2.7
88.7
4159
29604
OIKON, ,
NOMESCO Finland
10.0
81.0
102
86
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
17.5
79.0
73
35
Z01.2
ICD-10 Finland
Dental examination
1.8
77.8
2978
19080
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
4.1
77.6
234
492
OIKNV, ,
NOMESCO Finland
12.8
75.8
82
54
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
75.7
2333
13967
SAA01
NOMESCO Finland
Simple examination of mouth
2.2
75.7
3908
27517
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.1
75.1
836
3580
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
15.7
73.0
71
38
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
12.6
71.6
78
52
WX110
NOMESCO Finland
Infiltration anesthesia
1.9
61.6
3702
26107
SJE90
NOMESCO Finland
Orthodontic finishing
6.0
61.1
117
165
K07.10
ICD-10 Finland
Asymmetry of jaw
9.2
60.8
81
74
EB1S1
NOMESCO Finland
Photography of teeth
5.9
59.7
116
166
OIKJA, ,
NOMESCO Finland
5.1
59.2
134
222
K07.32
ICD-10 Finland
Displacement of tooth or teeth
9.7
57.7
74
64
-1, ,
NOMESCO Finland
1.6
57.1
2406
15223
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
4.2
55.8
163
334
D19
ICPC
Teeth/gum symptom/complaint
1.6
53.4
1847
11057
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
2.5
52.0
379
1344
K03.66
ICD-10 Finland
Tooth plaque
2.0
50.6
618
2710
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.9
49.8
701
3228
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.6
49.5
1895
11566
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
7.4
49.3
78
89
SPAT1386
SPAT
Extensive health check-up on eighth grade
1.8
49.2
895
4475
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
6.5
48.8
86
111
OIKTA, ,
NOMESCO Finland
7.8
48.2
73
79
K03.64
ICD-10 Finland
Dental calculus supragingival
1.6
48.0
2186
13869
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.8
46.5
260
808
SCA01
NOMESCO Finland
Preventive oral health care, short
1.6
46.1
2680
17918
OIKLI, ,
NOMESCO Finland
21.7
46.0
39
15
D82
ICPC
Teeth/gum disease
1.6
46.0
2243
14405
EBA10
NOMESCO Finland
Operative extraction of tooth
1.7
45.4
1267
7117
K02.0
ICD-10 Finland
Caries limited to enamel
1.6
44.9
1757
10710
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.0
42.9
526
2301
SPAT1315
SPAT
Periodic health check-up of children and adolescents
1.5
42.9
2168
13951
K07.60
ICD-10 Finland
Snapping jaw
2.2
42.4
395
1556
EB1WA, ,
NOMESCO Finland
7.4
41.2
65
74
K01.0
ICD-10 Finland
Embedded teeth
2.6
41.1
252
821
OIKIN, ,
NOMESCO Finland
4.6
39.6
101
186
K00.00
ICD-10 Finland
Hypodontia
2.9
39.0
199
588
SDA03
NOMESCO Finland
Periodontal treatment
1.5
37.9
1884
11975
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
4.5
37.9
99
186
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
9.5
37.1
48
42
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
36.6
1541
9437
K01.12
ICD-10 Finland
Retained canine with obstruction in the upper jaw
5.5
36.4
75
114
EBB10
NOMESCO Finland
Insertion of dental implant
4.8
36.0
87
153
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
13.2
35.8
38
24
ECA00
NOMESCO Finland
Surgical exposure of tooth
4.1
35.3
103
211
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
2.2
35.1
337
1342
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.3
35.0
275
1006
SCA02
NOMESCO Finland
Preventive oral health care
1.6
34.9
1207
7061
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
8.5
33.6
47
46
SPAT1316
SPAT
Extensive health check-up of children and adolescents
1.5
32.4
1478
9149
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
10.9
32.1
38
29
Z00.1
ICD-10 Finland
Routine child health examination
1.5
31.3
1150
6790
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.4
30.5
1946
12821
SPC20
NOMESCO Finland
Implant borne crown
6.6
29.3
51
65
ECA70
NOMESCO Finland
Regenerative periodontal surgery or gingival graft
10.0
28.8
36
30
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
5.4
28.5
60
93
SJC04, ,
NOMESCO Finland
5.5
28.5
59
90
SXC03
NOMESCO Finland
Other oral or dental procedure
5.1
27.3
61
100
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.9
27.0
85
185
Z3229
NOMESCO Finland
Other healthcare associate professional
2.0
26.9
323
1396
WYA10
NOMESCO Finland
Emergency care or similar visit
1.8
26.6
414
1949
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
6.8
26.2
44
54
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.5
25.8
1054
6323
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.3
25.5
197
715
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.7
25.2
586
3089
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
4.0
25.0
74
154
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
3.2
24.8
102
266
EMAK, ,
NOMESCO Finland
2.3
24.6
189
684
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.1
24.5
233
923
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.7
24.3
502
2564
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
2.9
24.3
122
358
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
3.4
24.0
91
225
602
Kela drug reimbursment
Children's severe malnutrition
3.3
24.0
95
242
RETH, ,
NOMESCO Finland
7.3
23.5
37
42
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
4.5
23.1
59
109
SCE00
NOMESCO Finland
Fissure sealant
1.6
22.8
542
2870
K07.4
ICD-10 Finland
Malocclusion, unspecified
2.7
22.7
132
419
EB3VA, ,
NOMESCO Finland
10.7
22.5
27
21
K06.18
ICD-10 Finland
Another gingival hyperplasia
5.6
22.4
45
67
SCA03
NOMESCO Finland
Preventive oral health care, extensive
1.8
22.3
399
1957
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
8.9
22.2
30
28
EB1TW
NOMESCO Finland
3D modelling of dentition
6.6
22.1
38
48
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.9
22.0
106
304
EBB15
NOMESCO Finland
Insertion of dental implant abutment
4.8
21.6
51
88
SPAT1385
SPAT
Extensive health check-up on fifth grade
1.8
21.4
324
1512
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
3.7
21.3
71
161
RETAL, ,
NOMESCO Finland
9.3
21.3
28
25
VALMI, ,
NOMESCO Finland
1.4
21.1
1726
11637
K07.61
ICD-10 Finland
Cracking jaw joint
2.2
20.4
188
735
SAE03, ,
NOMESCO Finland
5.6
20.4
41
61
H02AB09
ATC
hydrocortisone; systemic
2.3
19.9
151
545
127
Kela drug reimbursment
Transplant complication
3.3
19.7
79
203
Z94.0
ICD-10 Finland
Kidney transplant status
3.9
19.3
59
126
L04AA01
ATC
[U] ciclosporin
4.5
19.1
49
91
K07.38
ICD-10 Finland
Other anomaly in the position of the teeth
1.9
18.7
245
1091
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.6
18.6
65
153
SAE02, ,
NOMESCO Finland
3.0
18.5
84
233
EEC02
NOMESCO Finland
Rapid expansion of maxilla
39.9
18.4
24
5
SPAT1384
SPAT
Extensive health check-up on first grade
1.8
18.4
279
1302
K03.00
ICD-10 Finland
Approximal wear
1.7
18.3
375
1908
KIP00, ,
NOMESCO Finland
8.3
18.3
26
26
K07.3
ICD-10 Finland
Anomalies of tooth position
3.4
18.2
69
171
K02.1
ICD-10 Finland
Caries of dentine
1.3
18.1
3030
22497
OIKAK, ,
NOMESCO Finland
4.9
17.7
41
70
EB1KA
NOMESCO Finland
Partial (restricted area) panoramic tomography of teeth or jaw
4.1
17.5
51
105
A31
ICPC
General and Unspecified, Medical examin/health eval partial
1.9
17.4
229
1021
SFA10
NOMESCO Finland
One-surface restoration
1.3
17.1
2786
20511
KKOJE, ,
NOMESCO Finland
8.0
17.0
25
26
WX290
NOMESCO Finland
Other blockage of nerve
1.3
16.9
2627
19203
A11CC03
ATC
alfacalcidol; systemic
3.0
16.6
78
221
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.3
16.5
1287
8535
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
16.5
655
3872
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.7
16.5
40
71
K06.00
ICD-10 Finland
Local gingivore traction
2.5
16.2
106
358
SJF02, ,
NOMESCO Finland
4.0
16.1
48
101
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
15.8
3035
22725
FM2CE, ,
NOMESCO Finland
2.3
15.7
128
477
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
15.7
902
5697
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
15.4
703
4263
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
4.5
15.4
39
72
XF602
NOMESCO Finland
Bloodpressure monitoring
3.5
15.3
54
128
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
5.2
15.2
33
53
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.4
15.2
952
6092
B03XA01
ATC
erythropoietin; parenteral
5.3
15.2
32
50
K02.3
ICD-10 Finland
Arrested dental caries
2.1
15.2
145
577
R06.5
ICD-10 Finland
Mouth breathing
1.7
14.7
312
1602
L04AD02
ATC
tacrolimus; systemic
3.1
14.6
62
166
K00.10
ICD-10 Finland
The incisor and canine region, including the mesiodens
5.4
14.5
30
46
OIKSI, ,
NOMESCO Finland
5.6
14.5
29
43
H01AC01
ATC
somatropin; parenteral
2.7
14.5
78
239
137
Kela drug reimbursment
Uraemia requiring dialysis
4.3
14.4
39
76
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.4
14.2
858
5450
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
7.1
14.2
23
27
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
4.0
14.2
42
88
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
7.3
14.0
22
25
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
2.9
13.9
67
193
YEA05
NOMESCO Finland
Excision of gingival or connective tissue for transplantation
23.7
13.7
20
7
OIKPU, ,
NOMESCO Finland
3.4
13.6
51
126
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
13.6
2196
15934
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.3
13.6
1278
8659
XX4AW, ,
NOMESCO Finland
3.2
13.5
54
139
V03AG01
ATC
sodium cellulose phosphate; systemic
4.8
13.4
32
56
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.0
13.4
148
622
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
3.0
13.4
62
175
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
3.2
13.2
53
137
K01.17
ICD-10 Finland
Retained molar with obstruction in the lower jaw
1.6
13.2
356
1937
PURV0, ,
NOMESCO Finland
4.4
13.1
34
64
SAB03
NOMESCO Finland
Oral health check
1.4
13.1
795
5052
G47.3
ICD-10 Finland
Sleep apnoea
1.5
12.9
483
2816
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.0
12.8
146
621
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.4
12.8
797
5082
Z99.2
ICD-10 Finland
Dependence on renal dialysis
6.5
12.7
22
28
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
2.6
12.6
75
242
K07.34
ICD-10 Finland
Rotation of tooth or teeth
5.9
12.6
24
34
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.4
12.6
636
3919
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
3.0
12.4
56
156
WX882
NOMESCO Finland
High dependency care
1.9
12.1
164
739
SCD01
NOMESCO Finland
Removal of biofilm and supragingival calculus, short
2.3
12.1
94
344
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.0
11.8
128
535
K07.33
ICD-10 Finland
Crowding of tooth or teeth
3.3
11.8
45
113
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.0
11.5
52
145
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
3.0
11.5
52
145
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.9
11.5
149
663
EG1CG
NOMESCO Finland
Extensive MRI examination of mandibular joint with high intensity magnet
3.4
11.4
41
99
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
3.6
11.4
39
91
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
10.8
11.4
22
17
A12AA04
ATC
calcium carbonate; oral
3.2
11.4
46
120
SPC10
NOMESCO Finland
Standard dental crown
3.3
11.3
44
112
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
2.1
11.3
103
404
BE00A, ,
NOMESCO Finland
9.6
11.2
23
20
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
3.8
11.1
35
77
SDA05
NOMESCO Finland
Very demanding periodontal treatment
1.5
11.1
364
2068
WX704
NOMESCO Finland
Intubation
1.6
11.0
248
1292
K10.00
ICD-10 Finland
Torus mandibularis
3.9
10.8
33
71
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
11.1
10.6
20
15
K07
ICD-10 Finland
Dentofacial anomalies [including malocclusion]
3.2
10.5
43
113
K00.68
ICD-10 Finland
Other disturbance in the tooth eruption
1.7
10.5
206
1038
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.7
10.3
172
828
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.4
10.3
406
2390
OAA40, ,
SPAT
1.5
10.3
336
1907
Z37.0
ICD-10 Finland
Single live birth
0.6
10.2
188
2503
Z49.2
ICD-10 Finland
Other dialysis
4.2
10.1
28
56
KAC00
NOMESCO Finland
Nephrectomy
5.1
10.0
22
36
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
9.9
330
1881
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
3.6
9.9
33
76
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
4.3
9.8
26
50
XA800
NOMESCO Finland
Neuropsychological investigation
1.7
9.8
195
986
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.7
9.8
172
841
SAB02
NOMESCO Finland
Oral and dental health check by dental hygienist or dental assistant
1.3
9.7
1126
7776
A30
ICPC
General and Unspecified, Medical examin/health eval complete
1.7
9.7
161
774
SPAT1363
SPAT
Health check-up performed during first study year in students of upper secondary schools, vocational schools etc.
1.2
9.6
1535
10988
A98
ICPC
Health maint/preventive medicine
3.1
9.6
4556
37198
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
4.2
9.6
26
51
Z3231
NOMESCO Finland
Registered nurse
1.3
9.5
1012
6915
AA40B, ,
NOMESCO Finland
8.7
9.4
20
19
OIKAP, ,
NOMESCO Finland
4.2
9.4
26
52
K00.41
ICD-10 Finland
Prenatal enamel hypoplasia
3.5
9.3
33
79
EAB10
NOMESCO Finland
Excision and repair of frenum of lip
3.5
9.3
32
75
SXC05, ,
SPAT
11.8
9.3
17
12
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
9.3
9.3
19
17
E34.35
ICD-10 Finland
Abnormal growth retardation
2.2
9.2
75
281
ZXX07
NOMESCO Finland
Extent of procedure, 7 units
19.4
9.2
14
6
N18.8
ICD-10 Finland
Other chronic renal failure
3.0
9.1
40
110
SPC25
NOMESCO Finland
Other demanding attachment of prosthodontic crown
10.0
9.1
18
15
LEVY, ,
NOMESCO Finland
4.8
9.1
21
36
L01BA01
ATC
methotrexate; systemic
2.0
9.1
95
394
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.7
8.9
152
737
WZC00, ,
SPAT
1.3
8.9
836
5623
R5140
NOMESCO Finland
Monitoring the use of the aid
1.6
8.8
201
1053
L04AD01
ATC
ciclosporin; systemic
2.2
8.8
72
271
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
2.1
8.8
79
309
SCB02
NOMESCO Finland
Instructions for self-performed oral hygiene
3.0
8.7
38
104
4AA09, ,
NOMESCO Finland
8.3
8.7
19
19
HAMTE, ,
NOMESCO Finland
3.4
8.7
32
79
L04AA06
ATC
mycophenolic acid; systemic
2.3
8.5
67
248
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
8.5
662
4342
K00.7
ICD-10 Finland
Teething syndrome
1.3
8.4
505
3189
103
Kela drug reimbursment
Diabetes, insulin-treated
0.7
8.4
213
2643
SPAT1301
SPAT
No procedures
1.2
8.4
1248
8843
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
2.2
8.2
70
268
LKAAR, ,
NOMESCO Finland
30.4
8.2
11
*
ZXA10
NOMESCO Finland
Bilateral
1.3
8.2
504
3196
H65.3
ICD-10 Finland
Chronic mucoid otitis media
1.5
8.2
293
1695
OIKQH, ,
NOMESCO Finland
11.3
8.1
15
11
R05FA02
ATC
opium derivatives and expectorants; systemic
0.8
8.1
694
7072
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
4.8
8.1
19
33
T90
ICPC
Diabetes non-insulin dependent
0.6
8.1
145
1944
Z13.88
ICD-10 Finland
Special screening examination for other specified diseases and disorders
1.5
8.1
282
1623
K05.18
ICD-10 Finland
Chronic gingivitis
1.4
8.1
361
2175
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
2.6
8.1
45
142
K05.30
ICD-10 Finland
Periodontitis complex
1.4
8.0
300
1751
M01AB05
ATC
diclofenac; systemic, rectal
0.8
8.0
1362
12879
B05DA
ATC
Isotonic solutions
3.5
8.0
28
67
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.5
7.9
270
1546
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
7.8
495
3152
ZX199
NOMESCO Finland
Other rote
3.6
7.8
26
60
215
Kela drug reimbursment
Diabetes, non-insulin-treated
0.7
7.8
213
2600
A10BA02
ATC
metformin; oral
0.7
7.8
243
2890
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.4
7.7
304
1790
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
7.7
268
1541
ECA55
NOMESCO Finland
Complicated periodontal flap surgery
4.4
7.7
20
38
RLANK, ,
NOMESCO Finland
13.5
7.6
13
8
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
7.1
7.6
18
21
HMAK, ,
NOMESCO Finland
1.4
7.5
360
2195
SAD02
NOMESCO Finland
Assessment of need for oral health care, extensive
1.4
7.5
368
2253
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
1.5
7.4
213
1178
SPAT1325
SPAT
Vaccination
1.2
7.4
1473
10712
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
10.6
7.4
14
11
OAA31, ,
SPAT
1.7
7.4
135
669
101
Kela drug reimbursment
Anterior pituitary hypofunction
2.4
7.4
52
184
I10
ICD-10 Finland
Essential (primary) hypertension
0.8
7.4
506
5311
5AB14, ,
NOMESCO Finland
4.4
7.3
19
36
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
0.6
7.2
122
1659
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
3.0
7.2
32
89
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
2.5
7.2
46
156
K01.1
ICD-10 Finland
Impacted teeth
2.1
7.1
66
263
Q21.10
ICD-10 Finland
Persistent ostium secundum
2.3
7.0
54
199
Z29.8
ICD-10 Finland
Other specified prophylactic measures
1.6
7.0
181
979
SPB20
NOMESCO Finland
Temporary bridge
6.2
7.0
18
24
SCF03
NOMESCO Finland
Preventive oral care by dental hygienist, extensive
1.7
7.0
114
548
K01.14
ICD-10 Finland
Retained premolar with obstruction in the upper jaw
4.4
7.0
18
34
B05DB
ATC
Hypertonic solutions
3.6
6.9
23
53
EBA40
NOMESCO Finland
Extraction of apex of root of tooth
3.1
6.9
29
78
K07.39
ICD-10 Finland
Anomaly in the position of the teeth UNS
1.9
6.9
91
410
SCF02
NOMESCO Finland
Preventive oral care by dental hygienist
1.4
6.9
334
2040
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
4.2
6.9
19
38
SPA05
NOMESCO Finland
Surgical guide
12.4
6.9
12
8
A97
ICPC
No disease
1.2
6.8
994
7009
M01AE01
ATC
ibuprofen; systemic, rectal
0.8
6.8
3436
29731
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
6.4
6.8
17
22
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.2
6.8
773
5308
P01
ICPC
Feeling anxious/nervous/tense
1.2
6.8
1261
9102
R62.0
ICD-10 Finland
Delayed milestone
1.8
6.7
96
444
EB4VA, ,
NOMESCO Finland
1.2
6.7
749
5129
N01
ICPC
Headache
1.2
6.7
1167
8367
K01.16
ICD-10 Finland
Retained molar with obstruction in the upper jaw
1.6
6.7
155
818
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
3.0
6.7
29
80
XF400
NOMESCO Finland
ECG with 12 standard connections
1.3
6.6
382
2399
J34.2
ICD-10 Finland
Deviated nasal septum
1.7
6.6
130
658
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
6.6
1377
10036
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.1
6.6
28
76
SPAT1016
SPAT
Examination of vision
1.3
6.6
483
3140
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
2.5
6.5
41
138
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
0.1
6.5
*
182
SPAT1044
SPAT
Tympanometry
1.7
6.5
118
585
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.2
6.5
932
6558
E66.8
ICD-10 Finland
Other obesity
0.5
6.4
71
1083
K05.32
ICD-10 Finland
Periodontitis NOS
1.2
6.4
820
5695
A78
ICPC
Infectious disease other/NOS
1.7
6.4
119
593
OIKV, ,
NOMESCO Finland
3.3
6.4
24
60
K03.30
ICD-10 Finland
Internal granuloma of pulp
3.3
6.4
24
60
RL140, ,
NOMESCO Finland
2.7
6.4
33
100
V03AE01
ATC
polystyrene sulfonate; oral
3.6
6.4
21
48
HAHOM, ,
NOMESCO Finland
2.0
6.4
69
291
K01.13
ICD-10 Finland
Retained canine with obstruction in the lower jaw
6.3
6.3
16
21
WYA50
NOMESCO Finland
Student oral health check consistent with decree to assess need for oral health guidance and services
1.2
6.3
1040
7412
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
2.8
6.3
31
92
ZXE30
NOMESCO Finland
More than five and less than seven hours
1.6
6.3
131
674
SPAT1043
SPAT
Audiometry
1.4
6.3
260
1547
L17
ICPC
Foot/toe symptom/complaint
1.2
6.2
1212
8770
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
5.6
6.2
17
25
F59
ICD-10 Finland
Unspecified behavioural syndromes associated with physiological disturbances and physical factors
2.9
6.2
28
79
EFA50
NOMESCO Finland
Excision of cyst of jaws
2.9
6.2
28
79
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
1.2
6.1
824
5753
EDC30
NOMESCO Finland
Genioplasty
11.4
6.1
11
8
SJD70, ,
NOMESCO Finland
11.4
6.1
11
8
Z01.8
ICD-10 Finland
Other specified special examinations
1.2
6.1
683
4678
Q35.1
ICD-10 Finland
Cleft hard palate
3.6
6.1
20
46
M03BX02
ATC
tizanidine; oral
0.8
6.1
1440
13312
OIKEA, ,
NOMESCO Finland
13.8
6.0
10
6
SPAT1312
SPAT
General health counselling
1.2
6.0
1765
13213
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.4
6.0
327
2035
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
3.0
6.0
27
76

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
38
56
5.66
19.09
7.7
6.4
25372.73
681714.06
u/ml
0.56
11
16
43
79
4.54
17.02
8.3
8.9
2.44
2.44
mg/l
0.01
34
70
67
181
3.09
15.50
50.0
46.6
6.67
7.10
ug/l
0.99
62
163
257
1268
1.72
14.02
20.4
11.1
1.13
1.11
mg/l
0.27
249
1217
377
2159
1.49
11.01
17.1
9.7
6.34
6.18
mmol/l
0.27
365
2104
57
176
2.70
10.53
43.3
30.6
123.06
139.09
ug/l
0.53
51
152
338
1916
1.50
10.38
11.7
6.1
—
—
—
0
0
312
1765
1.50
9.68
12.8
6.4
9.78
9.64
kpa
0.74
298
1712
513
3186
1.37
9.56
10.9
6.0
7.37
7.37
ph
0.19
359
2021
503
3129
1.37
9.27
10.8
6.0
1.28
1.30
mmol/l
0.07
426
2623
511
3193
1.37
9.16
10.8
5.9
5.83
5.83
kpa
0.02
496
3108
578
3688
1.34
9.04
13.1
7.3
1.21
1.16
mmol/l
3.56
544
3473
411
2488
1.40
8.92
11.0
5.7
5.08
5.05
kpa
0.42
393
2402
407
2461
1.40
8.89
11.1
5.7
7.41
7.41
ph
0.01
330
2065
41
120
2.84
8.42
3.9
4.5
—
—
—
0
0
46
144
2.66
8.35
2.9
1.8
—
—
—
0
0
152
765
1.67
7.84
7.7
4.2
23.87
23.96
mmol/l
0.13
147
745
113
534
1.77
7.33
3.9
5.2
1.23
1.20
mmol/l
0.12
102
470
302
1797
1.42
7.25
5.7
3.5
68.85
69.58
e9/l
0.10
215
1184
416
2618
1.35
7.11
7.1
4.0
1.57
1.57
%
0.01
391
2401
452
2890
1.33
6.94
10.7
5.8
4.98
4.91
kpa
0.26
440
2815
138
702
1.65
6.88
4.8
3.6
26.40
25.53
nmol/l
0.26
138
683
447
2861
1.32
6.82
13.8
9.9
—
—
—
0
0
290
1735
1.41
6.77
9.1
5.2
69.77
64.43
ng/l
0.59
273
1616
20
44
3.77
6.43
1.4
1.4
9.08
5.40
pmol/l
—
10
17
3115
27146
0.84
6.36
3.8
3.7
2.69
2.73
mmol/l
1.76
2960
25936
304
1856
1.38
6.31
11.8
6.1
24.27
24.10
mmol/l
0.68
296
1820
186
2225
0.68
6.16
1.6
1.6
—
—
—
0
0
1597
11848
1.18
6.13
1.5
1.6
1.76
2.03
u/ml
0.35
381
3056
1679
12510
1.17
6.11
11.2
6.9
1.22
1.22
mmol/l
0.50
1508
11061
185
2201
0.68
5.96
1.6
1.5
—
—
—
0
0
520
3469
1.27
5.80
2.6
2.1
377.03
379.68
nmol/l
0.10
493
3248
3094
26911
0.85
5.79
3.6
3.4
1.47
1.45
mmol/l
1.58
2943
25719
45
169
2.22
5.66
2.4
2.4
0.92
0.18
mmol/l
0.71
36
147
179
2118
0.69
5.61
1.5
1.5
1.32
1.27
mm
0.84
139
1583
484
3214
1.28
5.61
1.4
1.3
264.44
297.53
u/ml
0.30
452
2975
67
298
1.87
5.38
4.1
3.1
—
—
—
0
0
42
157
2.23
5.36
2.3
1.7
—
—
—
0
0
89
433
1.72
5.33
2.8
3.1
1364.00
1386.50
e6/l
0.07
72
338
3127
27112
0.86
5.28
3.7
3.5
4.53
4.57
mmol/l
1.87
2976
26043
267
2918
0.74
5.18
1.5
1.5
72.34
61.80
ug/l
1.08
238
2525
179
1037
1.45
5.06
3.4
3.7
109.34
121.34
ng/l
0.20
166
895
2062
15794
1.15
4.83
8.9
6.8
8.46
8.27
%
2.83
1950
14968
273
1714
1.34
4.81
1.2
1.1
3.69
3.29
u/ml
0.21
190
1049
392
2586
1.28
4.80
2.5
2.1
10.71
10.07
nmol/l
0.66
362
2369
2052
15716
1.15
4.80
8.9
6.8
0.66
0.66
%
0.01
1940
14869
2055
15750
1.14
4.74
8.9
6.8
2.93
2.81
%
1.40
1946
14918
2866
24921
0.87
4.63
3.3
3.1
1.12
1.17
mmol/l
4.15
2719
23781
533
3659
1.23
4.63
4.3
3.4
29.35
29.53
s
0.36
523
3558
2112
16240
1.14
4.59
8.5
6.6
53.08
54.26
%
5.29
2043
15662
2148
16540
1.14
4.56
8.6
6.7
32.48
31.53
%
4.21
2064
15835
22
67
2.73
4.33
1.2
1.1
—
—
—
0
0
253
2712
0.76
4.31
1.5
1.5
1.26
1.16
ratio
0.50
153
1603
178
1067
1.40
4.23
7.8
4.7
540.15
351.80
mg/l
0.38
118
592
369
2458
1.26
4.20
5.6
5.0
0.02
0.21
%
0.70
108
522
2264
17555
1.13
4.17
8.9
7.1
0.19
0.19
e9/l
0.32
2003
15514
1472
11106
1.14
4.13
11.4
7.1
1.22
1.22
mmol/l
0.16
1387
10432
212
1313
1.35
4.13
1.1
1.1
1.99
6.77
eliau/ml
2.29
30
177
1367
10263
1.15
4.12
1.5
1.5
1.83
1.94
g/l
2.52
859
6415
61
289
1.76
4.09
3.1
3.4
0.28
0.31
e9/l
0.17
39
166
216
1344
1.35
4.08
5.6
4.4
3.08
3.32
g/l
2.24
209
1283
247
2634
0.76
4.06
1.5
1.5
—
—
—
0
0
176
1062
1.39
4.04
1.1
1.1
18.03
18.25
au/ml
0.01
26
257
222
1390
1.34
4.03
1.1
1.1
5.73
5.67
u/ml
0.02
157
806
359
2397
1.26
4.02
5.0
4.5
0.38
0.49
%
0.58
113
621
1116
8273
1.15
4.01
2.8
2.4
2.48
2.52
mg/l
0.24
981
7261
372
3765
0.80
3.97
1.8
2.0
—
—
—
0
0
144
842
1.43
3.96
6.3
3.9
24.59
24.80
mmol/l
0.30
136
806
534
3727
1.21
3.95
2.6
2.7
4.03
4.70
e9/l
2.44
479
3336
376
2535
1.25
3.88
3.8
3.4
0.22
0.22
g/l
0.02
354
2394
536
3753
1.21
3.84
4.2
3.5
738.54
734.18
ng/l
0.01
406
2936
26
92
2.35
3.84
1.2
1.2
22.50
26.19
u/ml
—
6
18
26
92
2.35
3.84
1.2
1.2
49.25
34.56
u/ml
—
8
12
90
481
1.56
3.83
1.2
1.2
—
—
—
0
0
91
488
1.55
3.82
2.2
1.8
—
—
—
0
0
91
488
1.55
3.82
2.2
1.8
—
—
—
0
0
91
489
1.55
3.79
2.2
1.8
—
—
—
0
0
91
489
1.55
3.79
2.2
1.8
—
—
—
0
0
2188
16993
1.13
3.78
8.7
6.8
0.04
0.04
e9/l
0.11
1907
14768
2261
17602
1.12
3.74
8.6
6.7
2.11
2.08
e9/l
0.57
2026
15707
369
2497
1.24
3.69
5.2
4.8
0.58
0.74
%
0.62
120
654
2523
19779
1.12
3.68
3.7
3.3
58.94
64.52
ug/l
1.61
2393
18884
2185
16991
1.12
3.65
8.7
6.8
0.54
0.54
e9/l
0.57
1911
14764
551
3893
1.19
3.59
3.2
3.1
516.95
638.79
ng/l
0.41
264
1942
545
3856
1.19
3.49
10.3
5.3
0.82
0.82
mmol/l
0.73
524
3678
90
493
1.52
3.47
1.2
1.1
2.56
6.17
iu/ml
3.29
19
120
72
375
1.60
3.46
2.6
3.1
526.33
548.85
e6/l
0.15
54
275
86
467
1.53
3.45
7.1
3.5
92.97
92.57
%
0.27
81
453
222
1427
1.30
3.40
5.0
3.8
21.19
21.08
s
0.13
205
1255
560
3982
1.19
3.40
3.5
2.5
2.54
2.53
g/l
0.15
513
3695
11
22
4.15
3.34
4.8
3.4
4.59
4.36
mmol/l
0.62
11
22
518
4988
0.84
3.32
4.8
4.5
12.54
10.94
mg/mmol
0.30
359
3418
354
2416
1.23
3.30
5.3
4.8
0.03
0.10
%
2.51
106
572
52
252
1.72
3.29
1.1
1.2
114.67
118.42
pmol/l
0.22
52
252
73
388
1.57
3.24
2.9
3.1
193.77
195.26
e6/l
0.02
56
292
136
821
1.38
3.19
1.2
1.2
—
—
—
0
0
412
2871
1.21
3.13
1.9
1.6
15.61
15.16
iu/l
0.13
338
2266
73
392
1.55
3.12
3.0
3.1
36.22
40.58
%
1.63
73
387
25
96
2.16
3.11
2.8
2.2
29.64
27.78
%
0.32
25
96
76
413
1.53
3.08
8.5
3.4
7.83
6.65
pmol/l
0.36
76
413
42
197
1.77
3.00
6.6
3.4
0.62
0.78
index
0.53
42
197
106
620
1.42
3.00
4.8
5.0
0.93
0.91
%
0.28
101
580
598
5642
0.86
2.98
1.6
1.6
1075.25
976.67
mu/l
1.17
539
5007
199
1286
1.29
2.97
1.1
1.1
12.09
8.91
u/ml
0.62
129
681
503
3589
1.18
2.95
3.7
2.6
23.77
23.40
%
0.25
468
3366
605
4382
1.16
2.94
3.5
2.5
14.88
14.66
umol/l
0.30
560
4118
518
4934
0.85
2.92
4.1
3.8
85.06
72.94
mg/l
0.38
367
3439
1795
13930
1.11
2.89
3.3
2.6
71.58
69.28
nmol/l
3.15
1702
13207
58
302
1.60
2.85
5.3
7.3
11.58
11.68
mmol/l
0.09
52
275
58
303
1.59
2.81
5.3
7.3
106.12
105.52
mmol/l
0.35
52
276
2376
18736
1.10
2.74
10.2
9.0
3.73
3.88
e9/l
2.79
2077
16206
6
8
6.21
2.66
7.0
2.3
140.00
139.13
mmol/l
—
6
8
5
5
8.28
2.64
7.8
5.2
225.80
168.40
mg/l
—
5
5
5
5
8.28
2.64
3.6
9.6
—
—
—
0
0
23
92
2.07
2.63
3.3
4.0
8.17
3.37
%
0.39
11
34
286
1959
1.22
2.63
1.2
1.2
3.99
3.16
u/ml
0.42
197
1170
51
263
1.61
2.63
4.4
3.6
25.61
25.15
umol/l
0.08
51
249
473
3392
1.17
2.63
1.7
1.5
—
—
—
0
0
1201
10750
0.90
2.59
2.0
2.0
—
—
—
0
0
368
2601
1.19
2.44
1.4
1.4
—
—
—
0
0
113
697
1.35
2.40
4.8
4.8
1.47
1.63
%
1.22
107
655
334
2345
1.19
2.40
2.1
1.7
7.43
7.89
u/l
0.37
251
1789
175
1149
1.27
2.37
1.1
1.1
0.19
0.57
u/ml
1.08
78
408
56
305
1.53
2.33
1.7
5.6
6.34
6.66
mmol/l
0.26
45
245
60
332
1.50
2.32
1.2
1.3
0.49
0.49
nmol/l
0.01
60
321
204
1370
1.24
2.29
8.5
5.0
132.38
132.72
g/l
0.08
197
1338
581
4292
1.14
2.17
1.2
1.2
—
—
—
0
0
22
94
1.94
2.16
2.0
3.0
1.25
1.14
umol/l
0.87
22
78
849
6423
1.12
2.14
3.2
2.9
102.67
105.74
ug/g
0.10
671
5124
2831
24193
0.92
2.09
4.0
4.0
35.41
36.23
mmol/mol
6.97
2700
23129
233
1607
1.21
2.06
1.7
1.4
—
—
—
0
0
3283
26463
1.09
2.02
4.3
4.3
14.32
14.38
pmol/l
0.77
2979
24304
58
685
0.70
2.00
5.6
7.5
—
—
—
0
0
9
26
2.87
1.99
1.4
1.3
—
—
—
0
0
15
57
2.18
1.98
5.6
6.2
—
—
—
0
0
23
104
1.83
1.94
1.7
2.0
16.20
19.43
nmol/l
—
5
31
21
309
0.56
1.92
16.9
18.2
802.81
807.01
nmol/l
0.02
21
300
51
286
1.48
1.91
1.0
1.0
19.57
17.48
u/ml
0.18
32
189
67
763
0.72
1.89
1.9
1.9
—
—
—
0
0
60
349
1.43
1.87
1.6
1.5
435.96
405.63
pmol/l
0.19
52
303
76
461
1.37
1.87
2.3
2.4
—
—
—
0
0
243
1703
1.19
1.84
1.2
1.1
1.17
1.36
u/ml
0.18
153
933
2570
20544
1.08
1.84
7.1
6.6
82.72
80.26
u/l
1.54
2452
19513
60
352
1.42
1.80
1.1
1.2
1.04
43.41
u/ml
1.18
50
256
244
1719
1.18
1.76
10.7
11.0
96.39
96.07
%
0.25
235
1671
57
333
1.42
1.75
3.9
3.3
1.83
1.75
umol/l
0.22
57
316
8
24
2.76
1.75
7.6
5.2
6.66
6.43
mmol/l
—
8
24
23
320
0.59
1.73
19.3
24.6
1181.17
1430.22
nmol/l
1.17
23
311
1279
11218
0.92
1.69
1.9
1.9
—
—
—
0
0
1695
14701
0.93
1.68
2.4
2.4
—
—
—
0
0
884
6791
1.10
1.65
5.5
3.7
7.39
7.39
ph
0.71
622
4606
1153
8962
1.09
1.65
5.4
6.6
1.09
1.09
inr
0.17
974
7472
10
34
2.44
1.63
1.0
1.2
—
—
—
0
0
271
1940
1.17
1.63
10.3
10.3
7.41
7.41
ph
0.01
147
980
1949
15467
1.07
1.63
11.1
9.5
0.00
0.00
e9/l
0.94
1599
12493
161
1104
1.21
1.58
2.4
1.6
118.68
123.99
au/ml
0.20
57
301
270
1938
1.16
1.58
10.3
10.2
5.04
5.04
kpa
0.01
260
1870
270
1938
1.16
1.58
10.3
10.2
14.46
13.95
kpa
0.69
260
1870
177
1742
0.83
1.57
1.3
1.3
—
—
—
0
0
11
184
0.49
1.56
1.1
1.1
—
—
—
0
0
13
52
2.07
1.55
1.8
2.4
—
—
—
0
0
64
391
1.36
1.55
3.0
2.7
—
—
—
0
0
48
279
1.43
1.55
1.2
1.3
—
—
nmol/l
—
0
0
247
1766
1.17
1.53
1.2
1.1
8.03
7.09
u/ml
0.35
177
1126
167
1154
1.21
1.53
2.4
1.6
—
—
—
0
0
27
139
1.61
1.51
1.0
1.1
1.38
2.94
u/ml
0.53
22
105
265
1907
1.16
1.51
10.3
10.3
0.41
0.29
mmol/l
0.21
204
1504
1071
8333
1.08
1.49
3.3
2.8
2.36
2.36
mmol/l
0.03
999
7768
92
597
1.28
1.48
3.6
3.5
3.26
3.83
e9/l
2.93
92
597
23
114
1.67
1.48
2.2
1.9
—
—
—
0
0
56
339
1.37
1.45
1.0
1.0
—
—
—
0
0
448
3351
1.12
1.43
1.8
1.4
—
—
—
0
0
48
284
1.40
1.43
1.2
1.3
0.17
0.23
nmol/l
0.36
38
210
489
3678
1.11
1.41
1.2
1.3
131.44
142.30
u/ml
0.22
171
1353
2592
22063
0.94
1.41
3.7
3.1
27.85
31.31
u/l
4.10
2499
21206
16
229
0.58
1.39
1.1
1.1
—
0.35
—
0
5
216
2066
0.86
1.39
1.6
1.6
—
—
—
0
0
53
321
1.37
1.38
1.2
1.3
18.26
14.27
u/ml
0.15
40
237
12
186
0.53
1.37
1.7
2.4
157.75
158.30
nmol/l
0.01
12
172
17
79
1.78
1.37
2.3
2.9
43.41
26.15
mg/l
—
8
36
96
634
1.26
1.37
1.2
1.3
7.65
4.65
u/ml
0.30
52
317
13
55
1.96
1.37
1.0
1.3
—
—
—
0
0
165
1157
1.19
1.32
2.4
1.6
36.56
22.01
u/ml
—
5
17
8
27
2.45
1.32
2.3
2.1
—
—
—
0
0
16
74
1.79
1.31
2.5
2.9
16.88
17.27
%
0.23
16
74
1316
10366
1.07
1.31
7.3
5.2
38.05
37.73
g/l
1.49
1243
9795
401
3667
0.90
1.31
1.4
1.4
3.24
3.28
mmol/l
0.30
251
2310
512
4621
0.91
1.30
1.5
1.6
3.27
3.33
ratio
0.46
354
3195
208
1490
1.16
1.29
2.2
1.5
186.21
202.57
u/ml
0.45
109
826
33
186
1.47
1.28
1.1
1.0
24.97
12.63
u/ml
—
6
37
30
166
1.50
1.27
1.6
1.3
—
—
—
0
0
1075
8417
1.07
1.27
5.0
4.3
—
—
—
0
0
200
1432
1.16
1.26
1.9
1.9
0.05
0.46
estimate
0.47
79
581
1635
12989
1.07
1.25
6.3
5.5
10.88
11.41
umol/l
0.82
1541
12130
37
429
0.71
1.25
1.9
1.9
1923.88
410.17
pmol/l
—
5
65
113
770
1.22
1.24
1.0
1.1
2.46
3.37
eliau/ml
0.47
44
325
35
202
1.44
1.22
1.9
1.7
1.23
2.97
nmol/l
0.93
28
154
84
555
1.26
1.22
1.3
1.2
8.60
11.16
u/ml
0.17
50
248
33
189
1.45
1.20
1.4
1.8
1.00
0.88
%
0.43
17
98
120
827
1.21
1.19
5.0
4.9
—
—
—
0
0
90
602
1.24
1.18
1.1
1.3
1.30
3.43
u/ml
1.82
57
307
252
1846
1.14
1.17
1.1
1.1
—
—
—
0
0
29
345
0.69
1.15
2.4
2.5
17.02
98.67
ug/min
3.08
18
234
35
205
1.42
1.14
1.9
1.6
—
—
—
0
0
24
130
1.53
1.14
1.2
1.1
—
—
—
0
0
33
192
1.43
1.12
3.5
2.3
10.61
10.53
mmol/l
0.05
33
186
221
2072
0.88
1.12
1.5
1.6
0.16
0.22
mg/l
1.28
77
880
369
2775
1.11
1.11
3.4
3.0
9.58
10.35
g/l
4.15
349
2597
697
5397
1.08
1.11
3.5
2.6
557.84
560.38
mosm/kgh2o
0.09
617
4733
3111
26238
0.94
1.11
3.3
3.3
5.39
5.50
mmol/l
7.33
2915
24712
24
131
1.52
1.11
1.0
1.0
—
—
—
0
0
75
496
1.26
1.10
1.1
1.1
0.37
2.08
u/ml
1.49
44
216
19
98
1.61
1.10
1.9
2.5
—
—
—
0
0
56
357
1.30
1.10
1.4
1.3
9.07
6.98
u/ml
0.26
37
216
821
6401
1.08
1.10
1.5
1.5
19.48
19.13
nmol/l
0.35
730
5750
89
601
1.23
1.09
1.5
1.3
—
—
—
0
0
5
17
2.44
1.09
1.4
1.0
195.20
300.35
u/ml
—
5
17
118
820
1.20
1.09
2.6
2.1
—
—
—
0
0
12
171
0.58
1.07
1.0
1.0
—
—
—
0
0
12
171
0.58
1.07
1.0
1.0
—
-0.06
—
0
20
107
741
1.20
1.04
2.6
2.9
203.28
340.54
ug/l
1.55
93
674
77
516
1.24
1.03
6.8
3.2
1.89
1.93
mmol/l
0.06
47
275
5
18
2.30
1.03
1.4
1.1
—
—
—
0
0
2149
17291
1.05
1.02
3.7
3.4
0.00
4.65
estimate
3.00
451
3576
170
1608
0.87
1.01
1.0
1.1
0.64
0.61
ratio
—
6
123
252
1868
1.12
1.01
3.8
3.2
7.35
7.35
ph
0.03
183
1353
294
2200
1.11
1.00
12.1
9.8
1.34
1.32
mmol/l
0.12
285
2161
68
696
0.81
0.99
1.1
1.1
—
—
—
0
0
3958
32415
1.08
0.99
12.4
10.8
19.84
20.65
mg/l
0.85
3020
25148
25
142
1.46
0.98
1.0
1.1
0.70
0.62
u/ml
0.05
13
72
10
44
1.88
0.97
1.9
2.8
96.40
101.09
g/l
—
10
44
180
1312
1.14
0.95
1.8
1.7
—
—
—
0
0
44
278
1.31
0.95
1.3
1.4
10.73
10.01
umol/l
0.27
44
265
75
507
1.23
0.95
1.1
1.1
9.92
14.50
u/ml
1.07
20
198
20
110
1.51
0.92
1.0
1.1
1.13
1.68
u/ml
0.39
15
81
37
229
1.34
0.92
1.8
1.4
—
—
—
0
0
380
2896
1.09
0.91
1.2
1.2
198.74
156.21
titre
0.12
19
95
52
339
1.27
0.90
3.7
2.3
80.44
77.04
mmol/l
0.17
45
297
422
3235
1.09
0.89
6.2
3.5
5.30
6.41
umol/l
1.61
358
2730
34
209
1.35
0.89
1.1
1.2
—
—
—
0
0
6
24
2.07
0.89
1.8
1.7
215.33
326.88
ug/l
—
6
24
6
24
2.07
0.89
1.0
1.0
—
—
—
0
0
8
35
1.89
0.88
1.0
1.2
—
—
—
0
0
1259
10022
1.05
0.88
3.0
2.7
0.02
0.06
estimate
0.79
384
2965
2148
17330
1.05
0.88
3.8
3.4
0.02
0.09
estimate
0.42
457
3489
242
1809
1.11
0.87
1.6
1.7
—
—
—
0
0
8
36
1.84
0.86
1.0
1.3
—
—
—
0
0
3907
32649
0.94
0.86
10.1
8.9
24.50
25.54
u/l
2.11
3780
31842
6
25
1.99
0.86
1.0
1.4
202.97
647.50
nmol/l
—
6
25
17
209
0.67
0.85
1.5
1.4
1.35
1.44
nmol/l
0.19
17
192
225
1677
1.12
0.85
5.6
3.1
1.23
1.23
mmol/l
0.20
202
1432
3639
29759
1.06
0.84
5.1
5.0
1.81
1.79
mu/l
0.22
3454
28473
61
618
0.81
0.84
3.7
2.9
24.05
25.07
mg/l
0.11
41
385
15
79
1.57
0.84
3.3
1.9
—
—
—
0
0
3620
29602
1.06
0.83
15.3
13.5
13.11
13.16
%
1.70
3566
29165
70
478
1.22
0.83
3.5
2.7
—
—
—
0
0
2013
16233
1.05
0.83
6.3
4.9
6.04
6.14
mmol/l
1.17
1827
14761
0
20
0.00
0.80
0.0
1.5
—
1.76
—
0
20
103
732
1.17
0.80
4.0
2.7
6.94
3.13
index
0.67
67
411
16
87
1.52
0.79
1.6
1.3
—
—
—
0
0
5
81
0.51
0.79
1.8
1.6
—
—
—
0
0
38
243
1.30
0.78
2.6
2.3
129.05
121.82
ng/l
0.16
33
216
409
3631
0.93
0.78
1.5
1.4
—
—
—
0
0
2115
17097
1.04
0.77
3.7
3.4
0.00
0.00
estimate
0.65
463
3600
10
134
0.62
0.75
1.2
1.1
—
12.17
—
0
6
34
363
0.77
0.75
1.2
1.2
—
—
—
0
0
277
2105
1.09
0.75
1.2
1.2
78.32
34.94
au/ml
1.34
12
100
74
724
0.84
0.73
1.1
1.1
—
—
—
0
0
20
117
1.42
0.72
1.4
1.4
134.75
137.08
nmol/l
0.09
20
117
168
1248
1.12
0.71
2.9
2.5
65.89
67.62
g/l
2.12
157
1191
24
146
1.36
0.70
1.6
2.3
105.33
105.75
mmol/l
0.24
24
146
7
97
0.60
0.68
1.0
2.0
—
—
—
0
0
13
70
1.54
0.68
5.8
4.5
4.82
5.34
kpa
1.35
13
70
587
4610
1.06
0.68
1.7
2.1
—
—
—
0
0
354
3139
0.93
0.68
1.3
1.2
—
—
—
0
0
29
183
1.31
0.68
1.2
1.1
25.27
34.63
iu/ml
0.79
29
183
1746
14090
1.04
0.67
3.4
3.1
6.36
6.29
ph
1.83
957
7782
510
3993
1.06
0.66
1.7
2.1
—
—
—
0
0
7
36
1.61
0.65
1.1
1.0
105.14
82.67
titre
—
7
36
24
148
1.34
0.65
1.6
2.3
4.00
3.93
mmol/l
0.45
24
148
1474
12543
0.96
0.65
1.7
1.8
—
—
—
0
0
121
888
1.13
0.64
2.4
1.9
3.43
3.47
mmol/l
0.18
116
840
40
266
1.25
0.64
1.2
1.2
—
—
—
0
0
26
163
1.32
0.64
1.0
1.1
3.98
1.13
u/ml
0.31
12
77
49
334
1.22
0.63
1.5
1.3
—
—
—
0
0
41
274
1.24
0.63
4.4
3.9
1.73
1.56
ug/l
0.19
41
266
162
1482
0.90
0.63
1.4
1.3
—
—
—
0
0
5
24
1.73
0.63
2.4
1.8
—
—
—
0
0
23
142
1.34
0.63
1.7
2.3
1.20
1.20
mmol/l
0.28
23
142
182
1370
1.10
0.63
3.8
2.8
9.75
5.95
umol/l
1.07
138
1050
59
578
0.84
0.62
1.2
1.3
—
—
—
0
0
112
820
1.13
0.62
3.1
2.2
1.05
1.25
g/l
2.78
104
724
631
4983
1.06
0.62
1.7
2.0
—
—
—
0
0
633
5000
1.06
0.61
1.7
2.0
—
—
—
0
0
24
150
1.33
0.61
2.2
2.2
158.46
137.26
au/ml
—
6
21
566
4459
1.06
0.61
1.5
1.6
8998402.92
30447424.74
pmol/l
1.08
489
3915
293
2260
1.08
0.59
2.3
2.3
17.36
18.37
au/ml
0.11
35
292
4392
36207
1.09
0.59
19.0
16.9
40.27
41.00
%
2.10
4344
35886
4392
36207
1.09
0.59
18.4
16.4
4.57
4.58
e12/l
0.67
4266
35349
22
137
1.33
0.58
1.1
1.2
0.10
1.05
u/ml
0.89
22
137
121
896
1.12
0.58
3.5
3.1
52.28
55.83
%
2.41
121
896
270
2080
1.08
0.57
1.2
1.2
—
—
—
0
0
4391
36204
1.09
0.56
18.4
16.4
29.66
29.71
pg
1.29
4345
35897
625
4951
1.05
0.56
2.5
2.5
8063.24
6745.19
u/l
0.35
211
1819
81
586
1.15
0.55
5.9
3.1
—
—
—
0
0
4394
36231
1.09
0.55
18.6
16.6
135.16
135.53
g/l
1.22
4351
35926
21
131
1.33
0.55
1.1
1.0
—
—
—
0
0
1173
9429
1.04
0.55
7.3
6.1
—
—
—
0
0
80
579
1.15
0.55
3.1
3.0
32.16
32.03
umol/l
0.02
74
546
1215
10343
0.96
0.54
1.8
1.8
1.24
1.29
mmol/l
0.98
1091
9278
794
6332
1.05
0.54
2.5
2.3
283.61
207.59
u/l
0.62
766
6075
366
2859
1.06
0.54
1.5
1.6
1146.70
1144.19
nmol/l
0.02
280
2232
25
161
1.29
0.54
1.0
1.1
0.72
7.19
u/ml
0.81
12
74
607
4811
1.05
0.53
1.5
1.5
391.29
513.91
titre
0.90
101
886
101
937
0.89
0.53
1.6
1.4
54.29
79.19
titre
—
7
123
185
1408
1.09
0.53
1.9
2.4
25.47
42.03
u/ml
1.13
177
1351
126
941
1.11
0.53
1.5
1.7
352.70
387.47
mu/l
0.64
105
782
619
4910
1.05
0.53
1.7
2.0
—
—
—
0
0
1037
8322
1.04
0.53
2.6
2.6
58.94
57.00
u/l
0.45
980
7740
126
943
1.11
0.52
1.2
1.1
—
—
—
0
0
327
2871
0.94
0.51
3.6
3.2
—
—
—
0
0
262
2316
0.93
0.50
1.6
1.6
63.09
59.95
ug/l
0.48
262
2316
4389
36198
1.08
0.50
18.4
16.4
88.52
88.74
fl
2.73
4343
35890
118
882
1.11
0.50
2.6
2.0
8.08
23.09
e6/l
2.06
74
642
10
55
1.51
0.50
8.3
3.1
0.23
0.22
%
—
10
55
119
891
1.11
0.49
2.6
2.0
105.11
4922.51
e6/l
0.57
81
681
352
2757
1.06
0.49
10.5
8.5
105.13
105.03
mmol/l
0.17
352
2757
7
91
0.64
0.49
1.0
1.1
—
—
—
0
0
28
186
1.25
0.48
1.1
1.1
5.78
2.97
nmol/l
—
5
30
16
98
1.35
0.48
1.3
1.4
102.82
95.30
nmol/l
0.15
11
75
4392
36229
1.08
0.47
18.5
16.5
6.78
6.79
e9/l
0.02
4269
35361
7
40
1.45
0.46
1.1
1.6
—
—
—
0
0
138
1046
1.09
0.46
1.2
1.2
—
—
—
0
0
45
317
1.18
0.45
1.0
1.2
—
—
—
0
0
4386
36183
1.08
0.45
18.5
16.5
264.33
265.00
e9/l
0.30
4266
35394
622
4961
1.04
0.44
1.7
2.0
—
—
—
0
0
14
154
0.75
0.43
2.0
2.5
44.43
42.82
%
0.10
14
154
14
154
0.75
0.43
4.0
5.0
10.57
8.32
%
0.44
14
154
88
654
1.12
0.43
3.0
2.2
136.65
133.82
g/l
0.61
78
570
6
77
0.64
0.42
1.3
1.6
—
—
—
0
0
46
328
1.16
0.41
1.1
1.2
—
—
—
0
0
29
198
1.21
0.41
3.5
2.6
2.27
31.93
nmol/l
0.52
29
186
104
945
0.91
0.41
1.3
1.3
5.83
17.43
u/ml
1.60
11
121
12
72
1.38
0.41
1.9
2.9
0.58
0.61
mmol/l
0.93
12
72
23
153
1.25
0.41
1.5
1.5
136.17
162.08
mmol/24h
1.17
23
153
401
3174
1.05
0.40
1.7
1.7
326.86
323.14
mu/l
0.08
365
2874
240
1872
1.06
0.40
3.2
2.4
0.17
0.32
e6/l
1.12
227
1783
151
1158
1.08
0.40
1.9
2.2
7.53
7.24
ug/l
0.03
138
1011
15
94
1.32
0.40
1.4
1.3
—
—
—
0
0
28
279
0.83
0.40
3.3
3.1
—
—
—
0
0
20
131
1.26
0.40
1.3
1.2
—
—
—
0
0
27
184
1.22
0.39
1.1
1.3
215.12
179.04
pmol/l
0.68
27
184
47
446
0.87
0.39
1.1
1.1
—
—
—
0
0
302
2377
1.06
0.38
3.1
3.5
4.77
4.79
pmol/l
0.11
277
2179
1252
10143
1.03
0.38
1.9
1.8
—
—
—
0
0
27
268
0.83
0.38
1.7
1.3
—
—
—
0
0
44
316
1.15
0.37
1.1
1.1
—
—
—
0
0
37
262
1.17
0.37
4.2
4.2
217.00
170.86
umol/l
0.28
26
153
855
6890
1.03
0.37
6.4
4.5
89.35
92.83
%
4.98
832
6731
1254
10166
1.03
0.37
1.8
1.7
97.26
97.35
pmol/l
0.02
672
5729
310
2449
1.05
0.35
2.8
3.1
33.69
32.43
%
1.32
234
1871
20
203
0.81
0.35
1.6
1.5
—
—
—
0
0
6
36
1.38
0.35
1.5
1.9
—
—
—
0
0
92
831
0.91
0.34
6.2
4.8
36.96
36.96
°c
0.01
92
820
172
1515
0.94
0.34
1.4
1.4
4.40
4.31
ug/l
0.04
158
1446
75
563
1.10
0.34
1.1
1.2
—
—
—
0
0
155
1368
0.94
0.33
1.6
1.6
7.82
7.13
u/ml
0.07
38
392
22
150
1.21
0.33
4.3
3.2
—
—
—
0
0
723
5825
1.03
0.33
3.9
3.9
—
—
—
0
0
6
75
0.66
0.33
1.0
1.1
—
—
—
0
0
35
334
0.87
0.33
3.1
4.2
450.36
97.78
u/ml
0.62
15
110
94
715
1.09
0.33
1.2
1.4
360.99
336.44
ug/g
0.47
48
360
295
2552
0.95
0.32
2.0
2.1
6.26
6.24
ph
0.17
170
1622
15
98
1.27
0.32
2.1
2.5
9.21
7.96
mmol/l
0.46
15
98
17
113
1.25
0.32
1.9
1.8
11.96
13.67
u/ml
0.08
12
91
73
550
1.10
0.31
1.6
1.5
0.58
0.52
e9/l
1.11
73
550
153
1346
0.94
0.31
1.1
1.1
—
—
—
0
0
391
3120
1.04
0.31
1.3
1.2
—
—
—
0
0
100
766
1.08
0.30
1.4
1.4
13.88
14.52
u/l
0.09
84
668
35
252
1.15
0.30
5.7
3.6
140.47
120.85
au/ml
—
8
43
76
687
0.91
0.30
2.0
2.0
9.79
10.15
mg/l
0.21
67
659
48
354
1.12
0.30
1.0
1.0
—
—
—
0
0
321
2765
0.96
0.30
1.5
1.5
—
—
—
0
0
34
245
1.15
0.29
1.3
1.3
69.24
68.00
ug/l
0.05
34
245
456
3898
0.96
0.29
1.2
1.2
—
—
—
0
0
10
108
0.77
0.29
1.5
1.2
—
0.06
—
0
6
11
117
0.78
0.29
2.6
2.8
—
—
—
0
0
273
2165
1.05
0.29
1.8
1.9
1.18
1.23
g/l
0.54
263
2041
1089
9182
0.98
0.28
4.5
3.2
47.29
72.18
e6/l
0.65
829
6743
466
3739
1.04
0.28
2.0
1.6
—
—
—
0
0
107
949
0.93
0.28
1.3
1.3
3.84
5.33
u/ml
—
9
84
15
100
1.24
0.28
1.1
1.2
—
—
—
0
0
10
107
0.77
0.28
1.1
1.2
—
3.56
%
—
0
9
1723
14078
1.02
0.27
3.1
2.8
—
—
estimate
—
0
0
47
349
1.12
0.27
1.1
1.2
—
—
—
0
0
48
441
0.90
0.27
1.2
1.3
—
47.00
—
0
21
19
131
1.20
0.27
1.0
1.2
—
—
—
0
0
19
131
1.20
0.27
1.0
1.2
—
—
—
0
0
426
3417
1.04
0.27
1.9
1.8
—
—
—
0
0
12
78
1.27
0.27
1.2
1.1
—
—
—
0
0
29
275
0.87
0.26
1.1
1.1
1.05
1.05
ratio
0.10
22
237
5
59
0.70
0.26
1.2
1.7
9.19
10.84
mmol/l
—
5
59
149
1167
1.06
0.26
14.9
13.6
0.69
0.66
%
0.34
149
1162
72
549
1.09
0.26
2.1
1.9
2.74
2.13
ug/l
0.17
65
491
25
178
1.16
0.26
1.1
1.2
—
—
—
0
0
795
6718
0.98
0.25
1.8
1.7
—
—
—
0
0
400
3415
0.97
0.25
2.2
2.1
—
—
—
0
0
9
61
1.22
0.25
1.0
1.1
—
8.73
—
0
7
127
992
1.06
0.25
1.2
1.4
—
—
—
0
0
888
7490
0.98
0.25
2.5
2.6
32.48
84.63
ng/l
0.77
369
3189
165
1435
0.95
0.25
1.7
2.1
4.49
6.64
iu/ml
0.80
36
346
114
1002
0.94
0.24
1.3
1.3
34.88
25.65
u/ml
—
5
43
32
299
0.89
0.24
1.5
2.2
22.65
28.18
mg/l
0.51
20
188
32
234
1.13
0.24
2.2
2.2
—
—
—
0
0
55
416
1.10
0.24
1.2
1.1
—
—
—
0
0
2532
20790
1.02
0.24
4.5
4.0
796.49
1874.37
e6/l
1.11
35
276
1590
13002
1.02
0.23
3.4
3.1
0.03
0.02
estimate
0.22
378
2964
62
473
1.09
0.23
1.5
2.8
—
—
—
0
0
19
134
1.17
0.22
1.8
2.3
—
—
—
0
0
340
2730
1.03
0.22
2.2
2.4
32.39
53.02
u/l
0.59
287
2273
3613
29775
1.02
0.22
13.1
10.6
139.56
139.53
mmol/l
0.37
3517
29022
21
150
1.16
0.22
1.9
2.3
—
—
—
0
0
0
9
0.00
0.21
0.0
1.4
—
829.81
—
0
9
0
9
0.00
0.21
0.0
2.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
75
664
0.93
0.21
1.1
1.1
—
—
—
0
0
6
39
1.27
0.20
1.0
2.1
41.22
42.85
g/l
—
6
39
6
40
1.24
0.20
2.3
1.9
4.67
2.65
%
—
6
40
0
12
0.00
0.20
0.0
1.2
—
—
—
0
0
6
41
1.21
0.20
1.7
3.4
3.50
4.70
ug/l
—
6
41
36
328
0.91
0.19
1.2
1.4
268.57
219.22
titre
—
7
64
21
198
0.88
0.19
1.4
1.6
—
—
—
0
0
1078
8803
1.02
0.19
2.6
2.4
—
—
—
0
0
22
160
1.14
0.19
1.4
1.4
12380.56
58725.79
e6/l
—
9
107
23
168
1.13
0.18
1.4
1.2
—
—
—
0
0
83
648
1.06
0.18
1.4
1.7
0.54
0.77
g/l
2.50
65
524
74
651
0.94
0.18
2.3
2.6
0.94
0.76
nmol/l
0.54
68
563
26
192
1.12
0.18
1.0
1.1
—
—
—
0
0
150
1192
1.04
0.18
14.9
13.4
94.86
94.41
%
0.33
150
1185
186
1485
1.04
0.18
2.6
2.5
0.60
0.66
ug/l
0.61
98
734
1230
10299
0.98
0.18
4.0
3.3
29.55
29.35
u/l
0.08
1179
9830
475
3850
1.02
0.18
2.7
2.2
2.40
2.41
mmol/l
0.40
422
3430
1382
11560
0.98
0.17
5.1
3.8
51.33
72.44
e6/l
1.40
910
7371
4070
33602
1.02
0.17
10.1
9.2
—
—
—
0
0
7
52
1.11
0.17
1.4
1.7
—
—
—
0
0
319
2708
0.97
0.17
1.3
1.3
220.60
226.69
miu/ml
0.11
158
1342
135
1163
0.96
0.16
3.1
2.4
1.02
1.02
ratio
0.30
117
1013
14
99
1.17
0.16
4.4
2.1
—
—
—
0
0
23
170
1.12
0.16
2.6
2.4
41.06
42.68
%
0.16
17
88
54
418
1.07
0.16
1.2
1.4
2.74
2.75
g/l
0.01
42
318
54
418
1.07
0.16
1.2
1.4
0.43
0.36
g/l
1.14
42
313
54
418
1.07
0.16
1.2
1.4
6.28
6.28
g/l
0.00
42
317
26
194
1.11
0.16
2.8
2.5
1.98
1.77
g/24h
0.17
15
122
106
917
0.96
0.15
1.3
1.2
—
—
—
0
0
18
131
1.14
0.15
1.0
1.2
—
—
—
0
0
983
8040
1.02
0.15
4.2
3.1
0.18
0.28
e6/l
2.05
717
5670
149
1190
1.04
0.15
14.9
13.4
1.04
1.24
%
3.79
149
1185
7
74
0.78
0.14
1.1
1.1
—
—
—
0
0
270
2181
1.03
0.14
1.2
1.2
—
—
—
0
0
130
1116
0.96
0.14
1.1
1.1
—
—
—
0
0
1042
8534
1.01
0.14
3.3
3.1
1.02
1.78
kg/l
1.35
683
5307
130
1115
0.96
0.14
1.1
1.1
—
—
—
0
0
14
132
0.88
0.13
1.5
1.5
0.00
0.02
estimate
0.50
14
132
115
917
1.04
0.13
2.5
2.2
—
—
—
0
0
753
6156
1.01
0.13
3.7
2.6
7.88
8.79
e6/l
0.67
693
5521
9
90
0.83
0.13
1.8
1.4
—
—
—
0
0
21
192
0.90
0.13
1.0
1.1
200.57
201.95
iu/ml
0.01
21
192
17
125
1.13
0.13
1.1
1.1
8.25
15.99
u/ml
—
10
73
21
157
1.11
0.12
1.7
1.3
90.23
84.34
nmol/24h
0.11
21
157
135
1082
1.03
0.12
2.0
2.2
4.05
3.56
iu/l
0.20
57
487
57
497
0.95
0.12
2.5
3.5
15.54
544.66
u/ml
1.19
50
433
48
375
1.06
0.12
2.5
2.3
3.60
3.28
u/ml
0.07
19
140
25
225
0.92
0.12
3.0
3.0
62.90
55.24
umol/l
0.59
25
213
24
216
0.92
0.11
3.2
2.6
865.58
754.56
u/ml
0.29
24
216
38
333
0.94
0.10
2.4
2.0
—
—
—
0
0
570
4665
1.01
0.09
3.8
2.9
3.60
4.23
e6/l
0.55
268
2161
5
40
1.03
0.09
1.8
2.2
1.94
1.94
ug/l
—
5
34
13
120
0.90
0.09
1.2
1.1
—
—
—
0
0
11
80
1.14
0.09
1.1
1.0
—
—
—
0
0
12
88
1.13
0.09
1.8
1.5
0.60
7.15
%
—
5
20
25
222
0.93
0.09
1.2
1.2
8.12
8.02
mm/h
0.03
25
222
6
44
1.13
0.09
2.2
2.0
—
—
—
0
0
960
7886
1.01
0.09
4.1
3.0
14.43
4.52
estimate
—
6
19
32
281
0.94
0.09
2.0
1.9
—
—
—
0
0
39
340
0.95
0.09
1.1
1.2
0.55
0.70
ratio
2.30
22
192
39
340
0.95
0.09
1.3
1.3
—
—
—
0
0
6
47
1.06
0.08
1.0
1.2
—
—
—
0
0
784
6437
1.01
0.08
2.9
2.2
1.11
1.05
mg/l
0.13
558
4619
332
2711
1.01
0.08
2.0
1.9
0.00
0.03
estimate
2.50
99
695
593
4864
1.01
0.07
3.7
2.8
0.89
1.15
e6/l
0.68
295
2370
25
194
1.07
0.07
5.4
5.0
—
—
—
0
0
8
64
1.03
0.07
1.0
1.0
0.36
0.20
u/ml
—
8
57
22
170
1.07
0.07
1.1
1.7
4.39
6.46
u/l
2.24
17
150
7
69
0.84
0.07
1.0
1.0
—
—
—
0
0
9
72
1.03
0.07
1.2
1.1
—
—
—
0
0
9
72
1.03
0.07
1.2
1.1
—
—
—
0
0
9
72
1.03
0.07
1.2
1.1
—
—
—
0
0
1109
9229
0.99
0.07
3.7
3.3
0.00
0.01
estimate
2.57
448
3451
35
303
0.96
0.06
1.3
1.1
1580.11
1442.82
miu/ml
0.32
35
303
3606
29803
1.01
0.06
13.3
10.7
3.89
3.89
mmol/l
0.29
3495
28948
678
5650
0.99
0.06
1.3
1.3
18.70
22.08
iu/ml
0.48
154
1434
11
82
1.11
0.06
1.0
1.1
21.57
25.21
u/ml
0.16
11
68
3939
32639
0.99
0.06
12.9
11.4
67.36
67.14
umol/l
0.18
3875
32218
141
1147
1.02
0.06
1.6
1.9
0.22
0.22
g/l
0.02
136
1103
17
131
1.07
0.05
1.4
1.8
0.80
3.83
u/field
—
10
101
20
176
0.94
0.05
1.0
1.1
—
—
—
0
0
52
417
1.03
0.05
1.3
1.4
—
—
—
0
0
1121
9316
0.99
0.05
2.9
2.3
—
—
—
0
0
138
1160
0.98
0.05
3.3
4.2
7.49
14.34
ug/l
0.43
88
829
37
295
1.04
0.05
7.5
4.8
8.11
9.47
mg/l
0.84
31
245
12
91
1.09
0.05
1.0
1.3
—
—
—
0
0
629
5176
1.01
0.05
3.6
2.7
312.20
312.35
umol/l
0.01
588
4765
35
299
0.97
0.03
1.3
1.3
950.00
1082.22
titre
—
10
45
306
2515
1.01
0.03
3.9
3.8
1.50
1.66
ug/l
0.44
275
2286
953
7913
1.00
0.03
3.7
3.3
0.80
0.24
—
5
25
16
140
0.95
0.03
1.2
1.1
25.83
227.19
ng/l
—
6
27
1020
8466
1.00
0.03
4.2
3.6
8.59
8.68
mmol/l
0.18
947
7687
85
693
1.02
0.03
1.2
1.2
252.84
2147.58
iu/ml
0.68
22
192
63
531
0.98
0.03
4.9
4.0
1.39
1.44
mmol/l
0.14
63
519
71
597
0.98
0.02
1.6
1.5
6.52
6.59
mmol/l
0.09
64
540
30
241
1.03
0.02
1.4
1.6
6.22
5.82
mmol/l
0.23
24
203
143
1174
1.01
0.02
1.6
1.9
1.14
1.18
g/l
0.63
137
1134
161
1342
0.99
0.02
1.2
1.3
0.21
0.70
u/ml
—
10
82
12
105
0.95
0.01
1.0
1.2
—
—
—
0
0
438
3616
1.00
0.01
2.1
2.6
—
—
—
0
0
158
1315
0.99
0.01
1.2
1.2
—
—
—
0
0
14
121
0.96
0.01
1.0
1.3
27.21
28.34
s
0.37
14
121
67
549
1.01
0.00
4.0
6.1
398.36
397.71
umol/l
0.01
61
498
621
5147
1.00
0.00
1.3
1.3
4.84
8.23
u/ml
1.17
229
2033
851
7051
1.00
0.00
3.1
2.3
—
—
—
0
0
22
177
1.03
0.00
1.5
1.3
—
—
—
0
0
36
303
0.98
0.00
3.2
3.2
44.57
54.75
mg/l
0.15
31
267
3681
30473
1.00
0.00
15.2
13.3
334.40
333.80
g/l
3.83
3643
30258
17
136
1.03
0.00
5.1
7.9
11.17
120.30
ug/l
0.54
12
105
18
152
0.98
0.00
3.7
2.1
1.75
2.34
u/field
—
8
103
43
358
0.99
0.00
1.9
2.4
287.14
288.53
mosm/kgh2o
0.25
37
276
36
301
0.99
0.00
1.0
1.1
—
—
—
0
0
24
202
0.98
0.00
1.0
1.0
9.97
8.86
mu/l
0.47
18
150
15
127
0.98
0.00
1.2
1.1
—
—
—
0
0
37
303
1.01
0.00
3.2
3.2
22.41
36.83
mg/l
1.31
32
265
33
271
1.01
0.00
3.4
3.0
1.63
1.61
ratio
0.02
22
150
144
1193
1.00
0.00
1.6
1.6
0.30
0.38
nmol/l
1.06
115
980
13
109
0.99
0.00
1.5
2.0
—
—
—
0
0
47
386
1.01
0.00
2.2
1.5
1.08
1.28
promille
0.41
36
293
49
401
1.01
0.00
1.1
1.1
32.61
37.20
mg/l
0.47
43
325
11
92
0.99
0.00
1.9
1.4
—
—
—
0
0
258
2140
1.00
0.00
2.1
2.6
—
—
—
0
0
27
225
0.99
0.00
2.0
1.7
44.90
50.13
%
0.26
21
160
23
193
0.99
0.00
3.0
2.2
16.03
16.14
umol/l
0.02
23
193
11
91
1.00
0.00
1.0
1.1
—
—
—
0
0
54
444
1.01
0.00
1.7
1.6
9030.05
13301.81
e6/l
0.77
38
327
21
176
0.99
0.00
1.3
1.3
68.33
70.08
umol/l
0.17
21
176
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.07
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
27.69
—
0
6
6
54
0.92
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
4339.20
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
56
0.89
-0.00
1.0
1.0
175.50
164.09
g/l
—
6
56
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
59
0.98
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
60
0.97
-0.00
1.1
1.3
5.06
5.45
mmol/l
—
7
60
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
0.44
—
0
5

Mortality – FinRegistry

Association

Association between endpoint K11_CROWDI_TEETH and mortality.

Females

Parameter HR [95% CI] p-value
K11_CROWDI_TEETH 1.111 [0.83, 1.49] 0.487
Birth year 0.997 [0.99, 1.01] 0.473

During the follow-up period (1.1.1998 — 31.12.2019), 130 out of 86830 females with K11_CROWDI_TEETH died.

Males

Parameter HR [95% CI] p-value
K11_CROWDI_TEETH 0.867 [0.6, 1.24] 0.439
Birth year 0.987 [0.98, 1.0] 0.017

During the follow-up period (1.1.1998 — 31.12.2019), 155 out of 72408 males with K11_CROWDI_TEETH died.

Mortality risk

Mortality risk for people of age

years, who have K11_CROWDI_TEETH.

N-year risk Females Males
1 0.108% 0.175%
5 0.622% 0.962%
10 1.505% 2.518%
15 3.189% 4.873%
20 5.74% 8.098%

Relationships between endpoints

Index endpoint: K11_CROWDI_TEETH – Crowding of teeth, including avohilmo

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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