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Systemic sclerosis, icd10

SYSTSCLE_ICD10

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M34
  • Cause of death: ICD-10 M34

2 out of 7 registries used, show all original rules.

978

4. Check minimum number of events

None

978

5. Include endpoints

None

978

6. Filter based on genotype QC (FinnGen only)

890

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF3
Parent code in ICD-10
M30-M36
Name in latin
Sclerosis systemica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 890 733 157
Unadjusted period prevalence (%) 0.23 0.26 0.07
Median age at first event (years) 56.24 55.99 57.42

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
923
Matched controls
9230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
50.8
312.3
184
45
L04AX03
ATC
methotrexate; systemic
12.3
312.1
418
583
M34.1
ICD-10 Finland
CR(E)ST syndrome
+∞
307.7
589
*
C08CA05
ATC
nifedipine; systemic
28.9
307.7
404
242
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
24.9
307.7
606
659
XX9XE
NOMESCO Finland
Other ultrasound examination
98.0
307.7
194
25
P01BA02
ATC
hydroxychloroquine; oral
21.7
307.7
519
515
I73.0
ICD-10 Finland
Raynaud syndrome
52.5
307.7
267
71
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
6841.0
307.7
411
*
L04AA06
ATC
mycophenolic acid; systemic
42.4
302.6
187
55
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
9.7
194.2
271
380
M34.0
ICD-10 Finland
Progressive systemic sclerosis
+∞
190.4
176
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
11.5
185.5
216
238
G04BE03
ATC
sildenafil; oral
52.7
171.5
99
21
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
7.4
166.0
304
572
L04AX01
ATC
azathioprine; systemic
10.8
140.1
165
182
L88
ICPC
Rheumatoid/seropositive arthritis
9.4
132.0
174
222
M34.8
ICD-10 Finland
Other forms of systemic sclerosis
+∞
120.5
113
*
L94.0
ICD-10 Finland
Localized scleroderma [morphea]
42.6
117.5
71
18
M35.1
ICD-10 Finland
Other overlap syndromes
46.5
116.6
69
16
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
9.5
115.5
149
184
XPX04
NOMESCO Finland
Angioscopy
222.9
115.5
117
6
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
12.2
113.7
120
112
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.2
101.7
500
2032
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
7.4
100.7
162
258
XG410
NOMESCO Finland
Flow-volume spirometry
8.6
91.7
126
167
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.1
87.3
654
3427
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
10.6
86.9
100
105
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
909.1
86.1
83
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.9
84.8
386
1451
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
9.5
80.7
100
116
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
13.3
76.1
74
60
R4120
NOMESCO Finland
Occupational therapy
5.5
75.3
164
348
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
5.2
72.2
171
390
C08CA02
ATC
felodipine; oral
4.8
70.1
185
461
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
16.5
68.9
59
38
QC6S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in hand
357.1
67.5
67
*
GD1AD
NOMESCO Finland
Thorax CT examination
5.2
60.6
137
298
K74.3
ICD-10 Finland
Primary biliary cirrhosis
25.0
60.5
43
18
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.4
57.4
270
1000
NH3EA
NOMESCO Finland
Feet X-ray examination with load
8.5
57.4
77
98
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.0
56.2
191
570
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
3.9
56.0
193
582
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
9.9
55.1
65
70
H02AB06
ATC
prednisolone; systemic
3.0
54.4
599
3536
M34
ICD-10 Finland
Systemic sclerosis
+∞
52.6
50
*
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
15.7
51.4
45
30
L01BA01
ATC
methotrexate; systemic
6.1
51.3
94
168
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
8.0
51.1
72
97
L04AD01
ATC
ciclosporin; systemic
10.4
49.4
56
57
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.7
47.5
489
2722
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.9
46.5
154
448
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
7.6
46.3
68
96
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.7
43.1
159
497
J99.1*M34.8
ICD-10 Finland
Respiratory disorders in systemic: sclerosis
+∞
42.0
40
*
L04AA01
ATC
[U] ciclosporin
11.0
39.6
43
41
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
7.2
39.4
60
88
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
12.7
38.6
38
31
C02KX01
ATC
bosentan; oral
+∞
37.8
36
*
WZA10
NOMESCO Finland
Extensive medical or dental certificate
9.2
36.6
45
51
TGC00
NOMESCO Finland
Bronchial lavation
6.4
36.2
62
103
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.2
34.3
97
250
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
47.5
34.0
41
9
A05AA02
ATC
ursodeoxycholic acid; oral
7.9
33.8
47
62
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.2
33.2
148
517
SBA10
NOMESCO Finland
Measurement of salivary flow rate
9.0
32.1
40
46
C08CA01
ATC
amlodipine; oral
2.2
31.3
440
2665
E0000UV, ,
ATC
2.2
28.5
479
3079
C02KX04
ATC
macitentan; oral
+∞
28.3
27
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
27.4
290
1546
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
5.7
27.2
52
96
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
6.1
27.2
48
82
J01FF01
ATC
clindamycin; systemic
2.2
26.4
317
1774
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.4
26.2
100
316
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.5
26.1
98
306
G73.7*M34.8
ICD-10 Finland
Myopathy in scleroderma
256.8
24.8
25
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
24.8
510
3471
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
24.7
273
1471
R06.0
ICD-10 Finland
Dyspnoea
2.1
24.2
324
1881
L99
ICPC
Musculoskeletal disease other
5.1
24.2
52
107
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
23.2
254
1360
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.1
22.6
101
351
H02AB07
ATC
prednisone; oral
2.4
22.1
174
808
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.3
22.0
90
296
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.8
22.0
120
466
RT172, ,
NOMESCO Finland
64.1
21.9
25
*
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
21.9
177
832
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.3
21.7
57
138
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.8
21.5
120
471
K22.4
ICD-10 Finland
Dyskinesia of oesophagus
18.0
21.4
33
19
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.9
21.3
65
176
RT160, ,
NOMESCO Finland
61.5
21.0
24
*
7101A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic sclerosis[SCLERODERMA]
+∞
20.9
20
*
K22.7
ICD-10 Finland
Barrett oesophagus
7.5
20.9
30
41
NHQ40
NOMESCO Finland
Amputation of toe
8.4
20.6
27
33
K62.3
ICD-10 Finland
Rectal prolapse
6.4
20.3
34
55
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
33.4
20.3
26
8
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.8
19.8
111
436
M01CC01
ATC
penicillamine; oral
75.2
19.8
22
*
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
7.0
19.6
30
44
RT274, ,
NOMESCO Finland
47.1
19.3
23
5
K22.1
ICD-10 Finland
Ulcer of oesophagus
7.1
19.2
29
42
I27.0
ICD-10 Finland
Primary pulmonary hypertension
56.3
19.0
22
*
A02BC02
ATC
pantoprazole; systemic
2.0
18.9
696
5550
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
18.1
151
716
A02BC01
ATC
omeprazole; systemic
1.9
17.9
289
1758
R4190
NOMESCO Finland
Nutritional therapy
3.7
17.9
59
169
M35.8
ICD-10 Finland
Other specified systemic involvement of connective tissue
32.1
17.1
22
7
R15
ICD-10 Finland
Faecal incontinence
3.6
17.0
57
165
C03CA01
ATC
furosemide; systemic
1.9
16.9
280
1714
UJF30
NOMESCO Finland
Ileoscopy through colon
2.3
16.8
136
635
XQ860
NOMESCO Finland
Laser Doppler measurement/scan of capillary perfusion
+∞
16.7
16
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.6
16.6
105
438
UJF32
NOMESCO Finland
Coloscopy
1.9
16.4
282
1744
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.3
16.4
33
64
ZX120
NOMESCO Finland
Intravenous
2.4
16.2
116
512
M05BA07
ATC
risedronic acid; oral
3.6
16.2
54
156
L95
ICPC
Osteoporosis
3.0
16.1
74
261
RT271, ,
NOMESCO Finland
38.8
15.4
19
5
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.4
15.2
110
488
R50.9
ICD-10 Finland
Fever, unspecified
2.1
15.2
162
845
R4180
NOMESCO Finland
Podiatric therapy
6.4
15.1
25
40
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
15.0
94
390
S97
ICPC
Chronic ulcer skin
2.8
14.9
78
295
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
32.3
14.8
19
6
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.7
14.5
83
329
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
4.3
14.2
37
89
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
14.2
113
523
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
14.2
411
2938
M05BX04
ATC
denosumab; parenteral
2.5
13.9
92
391
J01MA12
ATC
levofloxacin; systemic
2.0
13.9
184
1036
E000001, ,
ATC
1.9
13.9
207
1213
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
54.2
13.8
16
*
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
6.3
13.8
23
37
Z3226
NOMESCO Finland
Physiotherapist
1.9
13.6
194
1119
R4110
NOMESCO Finland
Physiotherapy
1.8
13.6
290
1896
D64.9
ICD-10 Finland
Anaemia, unspecified
2.3
13.6
110
512
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
13.5
133
672
J96.1
ICD-10 Finland
Chronic respiratory failure
5.1
13.4
28
56
RT272, ,
NOMESCO Finland
21.5
13.4
19
9
J01DB01
ATC
cefalexin; oral
2.0
13.3
784
6788
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
6.4
13.3
22
35
K11.2
ICD-10 Finland
Sialoadenitis
3.3
13.3
50
156
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.5
13.3
46
136
N02AX02
ATC
tramadol; systemic, rectal
1.7
13.3
416
3020
M05BA04
ATC
alendronic acid; oral
2.2
13.0
115
555
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
28.8
13.0
17
6
NDQ20
NOMESCO Finland
Amputation of finger
28.8
13.0
17
6
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.0
12.9
58
202
S01XA18
ATC
ciclosporin; ophthalmic
5.9
12.8
23
40
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.0
12.6
36
93
S09
ICPC
Infected finger/toe
3.4
12.5
46
142
R13
ICD-10 Finland
Dysphagia
2.4
12.4
91
406
A02BC05
ATC
esomeprazole; systemic
1.7
12.4
418
3077
TEA00
NOMESCO Finland
Biopsy of lip
5.9
12.3
22
38
C02DE02, ,
ATC
10.7
12.3
23
22
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.2
12.1
114
564
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
12.1
108
524
D06BX01
ATC
metronidazole; topical
2.0
12.0
135
716
RT231, ,
NOMESCO Finland
47.3
11.9
14
*
M13.9
ICD-10 Finland
Arthritis, unspecified
2.4
11.9
86
381
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.8
11.8
60
224
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
16.7
11.7
18
11
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
19.2
11.6
17
9
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
11.5
288
1953
J02AC01
ATC
fluconazole; systemic
1.6
11.4
434
3269
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
11.3
363
2620
RT310, ,
NOMESCO Finland
35.5
11.3
14
*
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.5
11.3
71
295
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
5.8
11.0
20
35
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
3.8
11.0
34
93
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.8
10.9
54
198
B80
ICPC
Iron deficiency anaemia
3.8
10.9
33
89
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
10.9
133
725
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
10.9
148
837
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.7
10.8
59
228
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
10.8
116
603
GX1K5
NOMESCO Finland
Diffusion capacity
9.3
10.5
21
23
GD2SN
NOMESCO Finland
Lung ventilation SPECT
10.2
10.5
20
20
SPAT1263
SPAT
Sampling
1.6
10.5
387
2876
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
10.5
219
1409
XG466
NOMESCO Finland
Sleep oxymetry
3.5
10.4
36
107
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.3
10.4
38
117
GX1D5
NOMESCO Finland
Flow volume spirometry
13.3
10.2
17
13
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
4.3
10.1
26
62
S18
ICPC
Laceration/cut
1.6
10.1
448
3466
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
10.1
293
2052
JGC01
NOMESCO Finland
Laparoscopic rectopexy
5.1
10.1
21
42
PB1BC
NOMESCO Finland
Extensive angiography of upper extremity with X-ray
40.5
10.0
12
*
N03AX16
ATC
[U] pregabalin
1.7
10.0
237
1577
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
9.9
123
673
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.7
9.8
190
1194
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
26.3
9.8
13
5
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
26.3
9.8
13
5
L84
ICD-10 Finland
Corns and callosities
3.0
9.8
43
148
M35
ICD-10 Finland
Other systemic involvement of connective tissue
55.6
9.7
11
*
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.9
9.7
45
160
A03FA02
ATC
cisapride; oral, rectal
2.2
9.6
80
376
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
9.6
161
970
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
8.5
9.6
20
24
TPH04, ,
SPAT
4.9
9.6
21
44
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
4.1
9.6
26
65
C08DB01
ATC
diltiazem; oral
2.7
9.5
51
196
SPAT1255
SPAT
Intravenous administration of medicine
2.5
9.4
62
263
I73.1
ICD-10 Finland
Thromboangiitis obliterans [Buerger]
101.0
9.4
10
*
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
101.0
9.4
10
*
I78.8
ICD-10 Finland
Other diseases of capillaries
101.0
9.4
10
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.7
9.4
49
185
R22.3
ICD-10 Finland
Localized swelling, mass and lump, upper limb
3.5
9.4
32
94
M34.2
ICD-10 Finland
Systemic sclerosis induced by drugs and chemicals
+∞
9.4
9
*
383
Kela drug reimbursment
Selexipag
+∞
9.4
9
*
B01AC27
ATC
selexipag; oral
+∞
9.4
9
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
9.4
360
2683
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
9.3
184
1163
B02.9
ICD-10 Finland
Zoster without complication
2.2
9.3
80
382
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
13.8
9.2
15
11
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.4
9.2
66
292
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
4.8
9.1
20
42
R1250
NOMESCO Finland
Evaluation of functional capability
3.1
9.1
37
122
G04BE08
ATC
tadalafil; oral
37.1
9.0
11
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
8.9
102
543
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.6
8.9
51
203
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
2.9
8.8
40
140
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.4
8.8
31
93
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.9
8.8
126
722
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
8.8
144
860
R02
ICPC
Shortness of breath/dyspnoea
1.8
8.8
138
815
Z2221
NOMESCO Finland
Medical doctor
1.6
8.7
263
1848
R76.0
ICD-10 Finland
Raised antibody titre
14.2
8.7
14
10
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
50.5
8.7
10
*
G73.7
ICD-10 Finland
Myopathy in other diseases classified elsewhere
50.5
8.7
10
*
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.1
8.7
36
120
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.4
8.5
58
250
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.7
8.5
44
166
NDQ48
NOMESCO Finland
Revision or amputation or exarticulation of finger
20.2
8.5
12
6
L12
ICPC
Hand/finger symptom/complaint
1.7
8.4
184
1191
WZC30
NOMESCO Finland
Teaching
1.7
8.4
161
1005
J01MA14
ATC
moxifloxacin; systemic
2.0
8.4
92
482
J01MA02
ATC
ciprofloxacin; systemic
1.5
8.4
335
2505
M43.9
ICD-10 Finland
Deforming dorsopathy, unspecified
+∞
8.3
8
*
C02KX02
ATC
ambrisentan; oral
+∞
8.3
8
*
A02BC03
ATC
lansoprazole; oral
1.6
8.2
279
2010
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
8.1
271
1943
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
4.6
8.1
19
42
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
3.3
8.1
30
93
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
4.1
8.1
22
55
XF622
NOMESCO Finland
Measurement of minute volume of heart
22.2
8.0
11
5
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
8.0
366
2807
TQW80
NOMESCO Finland
Local dermatologic skincare
3.3
8.0
30
94
D07AC01
ATC
betamethasone; topical
1.5
8.0
339
2561
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.2
7.9
68
324
SPAT1254
SPAT
Administration of medicine
1.8
7.9
128
762
WX002
NOMESCO Finland
Sedation and analgesia
1.7
7.8
180
1181
M05BB03
ATC
alendronic acid and colecalciferol; oral
3.1
7.8
32
106
A06AC51
ATC
ispaghula, combinations; oral
2.3
7.8
56
248
E000003, ,
ATC
2.5
7.8
48
198
E000006, ,
ATC
2.1
7.7
77
389
M31.4
ICD-10 Finland
Aortic arch syndrome [Takayasu]
45.4
7.7
9
*
A10BA02
ATC
metformin; oral
0.5
7.7
102
1711
NF1AA
NOMESCO Finland
Hip X-ray examination
1.9
7.7
92
497
C03DA01
ATC
spironolactone; oral
1.8
7.7
111
638
EBA10
NOMESCO Finland
Operative extraction of tooth
1.9
7.7
102
571
SPAT1360
SPAT
Extensive global examination
2.2
7.6
64
303
M33.2
ICD-10 Finland
Polymyositis
12.0
7.6
13
11
A03
ICPC
Fever
1.7
7.6
156
993
J01CA04
ATC
amoxicillin; systemic
1.6
7.6
751
6724
B01AC04
ATC
clopidogrel; oral
1.7
7.5
132
804
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
7.2
7.5
17
24
J05AB01
ATC
aciclovir; systemic
1.6
7.5
224
1564
D02AX
ATC
Other emollients and protectives
2.8
7.5
36
131
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.7
7.5
154
981
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
8.5
7.3
15
18
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
6.9
7.3
17
25
L94.3
ICD-10 Finland
Sclerodactyly
+∞
7.3
7
*
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
7.3
7
*
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
9.5
7.3
14
15
NJ3CG
NOMESCO Finland
Extensive MRI examination of extremities with median high magnet
9.5
7.3
14
15
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.8
7.3
125
756
K11.71
ICD-10 Finland
Xerostomy (dry mouth)
3.9
7.3
21
55
R60.0
ICD-10 Finland
Localized oedema
1.8
7.3
126
764
XQ848
NOMESCO Finland
Dermatological photography
2.9
7.3
33
116
SPAT1211
SPAT
Application of soft bandage
2.0
7.3
82
434
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
2.6
7.3
42
168
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
7.2
357
2766
M70.2
ICD-10 Finland
Olecranon bursitis
3.1
7.2
30
100
A07AA09
ATC
vancomycin; oral
4.5
7.2
17
38
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.0
7.2
73
372
GDG10
NOMESCO Finland
Bilateral transplantation of lung
30.3
7.2
9
*
JDA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in stomach or pylorus
30.3
7.2
9
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
7.1
111
652
S20
ICPC
Corn/callosity
3.4
7.1
25
75
PD4AD
NOMESCO Finland
CT of lower extremity arteries
6.6
7.1
17
26
H03AA01
ATC
levothyroxine sodium; systemic
1.5
7.1
250
1806
NFQ20
NOMESCO Finland
Amputation of femur
8.0
7.1
15
19
K76.9
ICD-10 Finland
Liver disease, unspecified
3.8
7.1
21
56
D50.8
ICD-10 Finland
Other iron deficiency anaemias
4.1
7.1
19
47
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
4.1
7.1
19
47
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
7.1
100
570
M43.0
ICD-10 Finland
Spondylolysis
3.5
7.0
23
66
SFA00
NOMESCO Finland
Small restoration
1.7
7.0
142
899
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.0
7.0
30
102
Z3229
NOMESCO Finland
Other healthcare associate professional
2.0
7.0
75
390
C08CA03
ATC
isradipine; systemic
4.4
7.0
17
39
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
4.2
6.8
18
44
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
6.8
6.8
16
24
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.1
6.8
28
93
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
11.0
6.8
12
11
L01AA01
ATC
cyclophosphamide; systemic
11.0
6.8
12
11
RJ420, ,
NOMESCO Finland
9.4
6.8
13
14
L94.9
ICD-10 Finland
Localized connective tissue disorder, unspecified
40.4
6.8
8
*
M25.5
ICD-10 Finland
Pain in joint
1.5
6.8
333
2572
E000002, ,
ATC
1.8
6.7
100
580
RT171, ,
NOMESCO Finland
22.7
6.7
9
*
Z94.2
ICD-10 Finland
Lung transplant status
22.7
6.7
9
*
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
22.7
6.7
9
*
SPAT1229
SPAT
Assessment of need for aid
2.0
6.7
70
361
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
3.8
6.7
20
54
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
6.7
138
879
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
6.5
6.7
16
25
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
5.5
6.6
18
33
M43.1
ICD-10 Finland
Spondylolisthesis
2.3
6.6
49
220
GD1UN
NOMESCO Finland
Lung circulation SPECT
7.9
6.6
14
18
I50.0
ICD-10 Finland
Congestive heart failure
2.2
6.6
56
267
RK220, ,
NOMESCO Finland
10.1
6.5
12
12
SPAT1312
SPAT
General health counselling
1.5
6.5
271
2021
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
6.5
120
740
J01AA04
ATC
lymecycline; systemic
1.7
6.5
120
741
D02AE01
ATC
carbamide; topical
2.1
6.5
63
316
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
6.2
6.5
16
26
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
6.4
166
1116
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
6.4
102
603
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
4.1
6.4
17
42
PHD76
NOMESCO Finland
Resection of long saphenous vein
2.2
6.3
51
238
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
6.3
72
383
ZX108
NOMESCO Finland
Inhalation
9.3
6.3
12
13
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
6.3
255
1893
XQ844
NOMESCO Finland
Other microscope or electron microscope examination
+∞
6.3
6
*
A46
ICD-10 Finland
Erysipelas
1.7
6.2
118
733
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
2.4
6.2
41
175
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
6.2
149
985
J94.8
ICD-10 Finland
Other specified pleural conditions
4.0
6.2
17
43
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.3
6.1
43
189
J01DA01
ATC
[U] cefalexin
1.4
6.1
561
4818
R81
ICPC
Pneumonia
2.5
6.1
38
158
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
6.1
110
675
L17
ICPC
Foot/toe symptom/complaint
1.4
6.1
294
2254
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
6.1
130
835
K29.7
ICD-10 Finland
Gastritis, unspecified
2.4
6.1
40
171
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.9
6.0
73
396
L04AA13
ATC
[U] leflunomide
2.7
6.0
31
117
NDL52
NOMESCO Finland
Tenosynovectomy of hand
5.2
6.0
17
33
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
1.7
6.0
110
677
A01AB09
ATC
miconazole; local oral
1.8
6.0
88
508

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
310
277
16.35
313.36
2.4
1.7
0.20
0.24
g/l
5.76
298
267
427
299
25.71
307.65
1.7
1.2
3.33
2.48
u/ml
0.43
103
30
433
413
18.87
307.65
2.6
2.0
6.83
8.00
iu/ml
0.25
142
93
350
245
22.40
307.65
1.7
1.2
37.21
57.81
u/ml
0.73
62
25
423
300
25.18
307.65
1.8
1.3
8.28
5.12
u/ml
0.58
155
46
431
316
24.71
307.65
1.7
1.2
7.77
29.06
u/ml
0.84
29
16
293
128
33.07
307.65
1.7
1.3
104.39
89.36
u/ml
—
90
5
406
237
29.80
307.65
1.7
1.2
30.82
6.81
u/ml
1.90
58
15
336
250
20.56
307.65
1.6
1.3
4.70
—
u/ml
—
12
0
310
289
15.65
304.89
2.4
1.7
1.09
1.21
g/l
6.17
299
276
579
1325
10.04
280.81
2.0
1.4
1897.98
504.40
titre
39.11
387
300
324
396
12.07
263.18
1.7
1.2
6.98
1.33
u/ml
3.31
26
23
199
152
16.42
216.78
1.4
1.1
25.74
2.60
u/ml
—
19
5
704
2541
8.46
200.17
5.5
3.0
719.63
959.78
ng/l
1.45
660
2146
95
12
88.14
179.90
1.7
1.7
—
—
—
0
0
119
43
31.62
179.05
1.3
1.2
—
—
—
0
0
133
73
21.12
170.06
1.4
1.2
—
—
—
0
0
135
78
20.10
168.57
1.4
1.2
—
—
—
0
0
97
29
37.26
154.24
2.8
1.1
8.69
8.92
ug/l
0.12
97
29
836
4453
10.31
131.94
16.0
6.2
0.04
0.04
e9/l
0.98
809
3802
835
4444
10.22
131.85
15.9
6.2
0.57
0.56
e9/l
0.70
808
3796
836
4537
9.94
126.58
16.0
6.2
1.69
1.93
e9/l
9.27
812
3976
840
4601
10.18
125.23
16.5
6.4
0.19
0.19
e9/l
0.39
816
4003
122
104
13.37
122.66
1.4
1.1
20.82
70.43
u/ml
—
17
7
279
684
5.41
111.36
3.9
3.1
10.29
10.44
g/l
0.19
265
628
766
4109
6.08
109.16
15.4
6.2
58.07
57.04
%
1.88
760
3917
765
4100
6.06
109.11
16.1
6.4
9.14
8.64
%
5.41
757
3834
631
2922
4.67
109.01
14.5
6.0
—
—
—
0
0
762
4093
5.94
107.74
16.0
6.3
3.04
2.79
%
2.65
754
3821
769
4188
6.01
106.09
15.9
6.3
27.35
28.31
%
2.05
760
3956
754
4087
5.61
103.33
16.3
6.4
0.79
0.71
%
4.54
747
3801
838
4969
8.45
102.75
18.9
9.5
3.83
4.01
e9/l
1.89
810
4331
588
2693
4.26
100.40
3.5
2.2
102.75
192.12
u/l
3.24
572
2554
82
50
17.90
98.84
1.2
1.1
—
—
—
0
0
241
588
5.19
95.53
4.7
3.1
114.13
172.15
ng/l
2.25
233
538
112
126
9.98
92.70
1.6
1.2
—
—
—
0
0
767
4603
4.94
81.84
6.8
4.1
6.88
5.13
estimate
0.09
199
958
759
4559
4.74
79.87
6.8
4.0
0.00
0.00
estimate
0.50
197
928
214
549
4.77
78.73
1.8
1.8
1.43
1.30
g/l
0.54
199
501
763
4654
4.69
77.20
6.9
4.1
0.00
0.01
estimate
1.49
199
907
655
3674
3.70
73.41
5.5
3.6
6.30
6.24
ph
0.69
346
2068
467
2151
3.37
71.96
3.9
2.5
317.03
325.58
umol/l
1.02
436
1898
231
769
3.67
58.10
6.2
4.2
0.47
0.67
%
0.83
68
224
294
1146
3.30
57.51
3.9
3.3
4.97
4.92
e9/l
0.02
259
1001
413
1980
2.97
55.90
9.5
4.8
—
—
—
0
0
156
409
4.39
54.70
2.4
2.2
0.00
0.01
estimate
0.50
52
127
233
810
3.51
54.52
6.9
4.3
0.82
1.08
%
0.75
68
243
223
770
3.50
52.56
7.0
4.4
0.09
0.13
%
0.32
57
202
224
783
3.46
51.72
7.3
4.7
0.02
0.14
%
1.24
56
188
659
4181
3.01
50.81
3.7
2.6
80.77
79.06
nmol/l
0.87
626
3798
387
1870
2.84
50.49
1.4
1.3
38.64
30.79
iu/ml
0.43
163
593
114
253
5.00
48.97
1.4
1.2
1019.29
1147.50
titre
0.09
14
12
868
6607
6.27
48.35
16.9
8.0
77.42
78.50
u/l
0.25
863
6281
43
31
14.50
47.03
1.3
1.0
—
—
—
0
0
43
31
14.50
47.03
1.3
1.0
—
—
—
0
0
43
31
14.50
47.03
1.3
1.0
—
—
—
0
0
459
2509
2.65
45.79
7.2
4.2
0.00
0.00
estimate
0.99
196
896
107
247
4.77
43.72
1.4
1.2
90.00
91.85
titre
—
10
27
224
863
3.11
43.33
2.5
1.5
—
—
—
0
0
64
92
7.40
42.85
2.2
2.2
—
—
—
0
0
80
152
5.67
40.77
3.5
3.4
3.86
4.43
e9/l
1.52
80
152
595
3827
2.56
40.23
21.7
11.0
0.00
0.00
e9/l
0.19
543
3118
284
1298
2.72
39.61
1.4
1.2
—
—
—
0
0
649
4387
2.61
38.86
9.6
6.7
1.21
1.22
mmol/l
0.98
572
3800
213
850
2.96
38.28
2.4
2.1
0.00
0.03
estimate
0.78
58
164
91
207
4.77
37.74
2.0
2.1
122.66
128.09
g/l
0.71
32
164
357
1874
2.48
36.86
1.7
1.5
2.23
2.33
g/l
0.50
247
1125
596
3933
2.45
36.58
8.6
5.9
1.22
1.22
mmol/l
0.44
570
3642
508
3144
2.37
35.81
6.4
3.9
54.27
88.38
e6/l
1.00
362
2172
456
2696
2.37
35.71
5.1
3.8
7.39
7.40
ph
3.53
350
1931
69
130
5.66
35.42
1.4
1.2
7.25
6.00
u/ml
0.14
36
49
112
325
3.78
33.55
1.2
1.2
—
—
—
0
0
101
279
3.94
32.43
3.0
2.1
111.69
232.79
ug/l
3.21
94
260
82
198
4.45
31.49
3.6
3.2
57.59
59.67
%
0.74
82
198
280
1402
2.43
31.18
3.7
2.4
11.13
12.99
umol/l
4.23
271
1311
569
3837
2.26
30.89
6.8
4.6
35.73
36.00
g/l
0.60
545
3609
202
874
2.68
30.53
1.5
1.5
—
—
—
0
0
318
1720
2.30
29.36
1.3
1.3
12.66
11.26
u/ml
0.13
127
648
520
3454
2.16
28.35
6.9
3.9
0.03
0.08
estimate
0.54
179
773
245
1201
2.42
28.23
3.6
2.4
19.90
22.27
%
1.56
233
1128
378
2226
2.18
28.04
3.8
2.2
2.90
2.89
mg/l
0.04
346
1914
205
930
2.55
27.90
2.4
1.7
—
—
—
0
0
173
724
2.71
27.73
2.1
2.8
65.10
67.20
g/l
2.72
161
667
258
1311
2.34
27.27
3.6
2.4
2.35
2.35
g/l
0.05
248
1213
239
1186
2.37
26.60
2.8
1.9
—
—
—
0
0
367
2215
2.09
24.82
4.4
3.0
—
0.00
estimate
—
0
6
229
1149
2.32
24.63
1.5
1.6
—
—
—
0
0
322
1866
2.11
24.12
4.0
2.6
3.70
6.91
e6/l
5.71
309
1719
378
2331
2.05
23.89
4.6
3.1
0.20
0.41
e6/l
2.50
311
1694
42
72
6.06
23.71
1.9
2.1
1145.29
1131.41
e6/l
0.03
35
63
178
818
2.46
23.22
2.8
2.2
0.20
0.21
g/l
1.77
166
770
418
2700
2.00
22.96
4.9
3.2
17.97
73.10
e6/l
1.45
357
2056
62
155
4.22
22.69
1.6
1.8
0.50
0.83
g/l
1.34
49
128
263
1451
2.14
22.09
3.5
2.8
0.72
1.17
e6/l
3.00
179
747
388
2487
1.97
21.37
5.7
3.4
0.00
0.01
estimate
1.15
177
758
138
589
2.58
20.93
1.3
1.3
—
—
—
0
0
348
2178
1.96
20.31
5.1
4.1
—
—
—
0
0
605
4591
1.92
19.15
8.7
6.2
10.04
10.63
umol/l
0.83
583
4386
42
90
4.84
18.61
1.3
1.3
8.18
6.93
g/l
0.49
33
71
42
90
4.84
18.61
1.3
1.3
2.86
2.80
g/l
0.08
33
70
42
90
4.84
18.61
1.3
1.3
0.47
0.37
g/l
0.95
33
70
338
2163
1.89
17.96
1.4
1.3
0.56
1.44
u/ml
2.81
81
578
396
2672
1.84
17.73
10.3
6.0
—
—
—
0
0
182
942
2.16
17.58
2.7
2.6
1.88
1.85
%
0.15
168
847
172
872
2.20
17.50
1.8
2.1
344.65
381.36
nmol/l
1.12
159
817
27
16
17.35
17.47
1.1
1.3
—
—
—
0
0
199
1073
2.09
17.26
5.9
4.9
1.04
1.03
mmol/l
0.21
181
985
512
3764
1.81
17.04
15.0
13.1
1.19
1.20
inr
0.07
435
3093
50
132
3.95
17.00
1.3
1.4
150.00
153.55
au/ml
—
9
39
148
719
2.26
16.66
2.6
2.7
71.91
72.55
e9/l
0.07
115
531
24
34
7.22
16.16
1.5
1.0
—
—
—
0
0
39
89
4.53
16.03
1.3
1.3
—
—
—
0
0
198
1104
2.01
15.51
2.2
1.4
—
—
—
0
0
232
1367
1.93
15.49
1.5
1.8
—
—
—
0
0
85
333
2.71
15.19
2.0
2.1
10.33
10.38
g/l
0.02
79
304
27
47
5.89
14.99
1.4
2.3
353.47
484.24
e6/l
0.76
19
38
51
150
3.54
14.86
1.4
1.4
—
—
—
0
0
52
158
3.43
14.42
1.7
1.4
—
10.40
—
0
5
306
2006
1.79
14.37
7.3
4.2
1.02
1.77
kg/l
0.50
245
1331
37
91
4.19
13.84
1.8
1.5
52.41
57.37
%
0.28
22
57
27
51
5.42
13.78
1.6
2.4
199.10
232.50
e6/l
0.27
21
44
434
3166
1.70
13.75
3.4
3.5
2.35
2.36
mmol/l
1.06
403
2898
96
419
2.44
13.73
1.3
1.2
—
—
—
0
0
539
4181
1.70
13.44
4.4
3.0
104.70
104.08
ug/l
0.02
509
3918
28
56
5.13
13.43
1.8
1.6
44.18
38.70
%
0.22
13
31
165
911
1.99
13.12
10.9
7.8
4.85
5.10
kpa
2.86
159
886
85
358
2.51
13.11
2.0
1.9
1.52
1.56
g/l
0.11
77
314
888
8127
3.44
12.98
32.6
15.3
18.05
22.35
mg/l
4.63
802
6665
50
160
3.25
12.79
1.0
1.1
—
—
—
0
0
164
912
1.97
12.76
11.0
7.8
7.44
7.42
ph
3.35
100
511
29
63
4.72
12.66
1.7
1.3
—
—
—
0
0
70
274
2.68
12.52
1.5
1.4
314.91
293.12
ug/g
0.37
38
157
30
68
4.53
12.45
1.4
1.2
117.50
96.36
titre
—
8
11
432
3214
1.65
12.22
5.1
3.6
26.46
61.78
ng/l
0.98
304
2200
698
5881
1.77
12.17
6.4
4.0
—
7770.69
—
0
13
133
698
2.06
12.13
2.7
2.3
0.23
0.41
e6/l
0.81
124
663
30
70
4.40
12.01
1.7
1.3
2409.65
1693.34
e6/l
0.32
17
44
198
1195
1.84
11.94
2.0
2.3
170.92
118.99
ug/g
1.00
162
942
38
107
3.66
11.83
1.3
1.2
—
—
—
0
0
225
1415
1.78
11.82
5.3
3.1
0.82
0.82
mmol/l
0.08
208
1338
160
905
1.93
11.78
11.2
7.7
0.87
1.09
mmol/l
0.31
136
759
28
63
4.55
11.72
1.6
1.4
—
—
—
0
0
39
113
3.56
11.64
3.0
2.8
—
—
—
0
0
247
1609
1.73
11.43
5.2
3.9
225.17
312.20
ng/l
0.46
196
1196
399
2949
1.62
11.32
5.2
3.0
31.09
30.80
u/l
0.07
385
2779
126
665
2.04
11.29
9.3
6.6
9.10
8.92
mmol/l
0.12
119
640
665
5578
1.69
11.22
6.9
4.8
168.56
1787.17
e6/l
—
9
78
68
285
2.50
10.60
2.5
3.6
60.02
63.35
mg/l
0.05
61
245
26
61
4.36
10.35
1.7
1.3
6044.09
164587.00
e6/l
0.69
11
29
37
113
3.37
10.22
2.3
1.4
—
—
—
0
0
37
113
3.37
10.22
2.3
1.4
—
—
—
0
0
37
113
3.37
10.22
2.3
1.4
—
—
—
0
0
37
113
3.37
10.22
2.3
1.4
—
—
—
0
0
67
285
2.46
10.12
2.5
3.6
30.98
53.83
mg/l
0.96
59
244
20
22
9.27
10.05
1.2
1.4
29.40
28.95
s
0.08
20
22
26
63
4.22
9.94
1.8
1.8
—
—
—
0
0
126
696
1.94
9.88
4.0
3.6
1.23
1.23
mmol/l
0.94
117
601
238
1589
1.67
9.86
4.0
2.8
481.13
505.04
mosm/kgh2o
1.14
223
1406
347
2554
1.57
9.60
1.9
1.7
21.18
21.28
nmol/l
0.04
310
2150
368
2762
1.55
9.25
3.1
2.4
59.43
62.80
u/l
0.48
338
2551
108
581
1.97
9.13
1.3
1.3
37.17
37.28
au/ml
—
9
46
60
256
2.44
9.02
2.3
3.5
6.36
3.89
ratio
0.31
34
144
68
309
2.30
8.88
3.0
1.8
21.24
20.79
s
0.18
59
277
88
446
2.08
8.77
2.5
2.4
—
—
—
0
0
23
56
4.19
8.75
2.8
2.9
45.56
40.77
%
0.46
16
31
208
1379
1.66
8.73
1.7
1.7
1180.85
1205.19
nmol/l
0.14
166
1026
70
325
2.25
8.70
2.1
1.9
1.35
1.84
ug/l
0.22
61
296
279
1993
1.57
8.60
2.1
1.7
1.35
1.10
mg/l
0.40
231
1557
34
110
3.17
8.59
2.2
2.6
—
—
—
0
0
15
13
11.71
8.59
4.1
2.2
—
—
—
0
0
114
640
1.89
8.49
2.6
2.5
28.03
25.84
au/ml
0.09
17
62
476
3827
1.50
8.41
2.3
2.1
98.50
97.58
pmol/l
0.14
251
1913
584
4901
1.52
8.38
7.5
4.6
6.40
6.58
mmol/l
1.31
568
4654
48
191
2.60
8.36
1.3
1.6
—
—
—
0
0
51
212
2.49
8.12
1.7
1.6
4755.50
11744.92
e6/l
1.25
38
144
95
509
1.97
8.12
6.2
3.3
7.41
7.42
ph
1.12
86
428
40
147
2.80
8.12
1.3
1.3
307.50
247.02
u/ml
0.64
24
84
37
134
2.83
7.72
3.2
3.4
2.08
1.29
%
0.31
37
124
113
653
1.83
7.68
1.3
1.3
71.39
220.24
u/ml
2.64
106
603
154
975
1.70
7.63
2.8
2.5
5.68
6.45
umol/l
0.35
140
852
116
679
1.81
7.56
6.7
3.9
—
—
—
0
0
290
2151
1.51
7.32
6.6
3.8
92.40
93.08
%
0.19
281
2101
18
30
6.10
7.10
2.4
1.7
30.44
29.33
%
0.10
18
30
117
701
1.77
7.04
13.9
7.6
—
—
—
0
0
27
86
3.20
7.03
3.1
3.0
58.94
57.09
%
0.15
27
79
24
71
3.44
7.01
1.6
1.5
242597.19
135998.74
e6/l
0.16
16
43
17
28
6.16
6.79
1.2
1.3
—
—
—
0
0
34
127
2.74
6.73
1.2
1.1
—
—
—
0
0
190
1313
1.56
6.56
4.2
2.9
2.88
3.37
e6/l
0.22
102
606
167
1120
1.60
6.55
12.0
6.2
103.99
104.05
mmol/l
0.05
167
1120
158
1051
1.61
6.41
1.3
1.3
—
—
—
0
0
12
13
9.33
6.30
1.0
1.2
—
—
—
0
0
12
13
9.33
6.30
2.8
7.9
6.88
4.96
kpa
0.45
12
13
12
13
9.33
6.30
1.0
1.0
—
—
—
0
0
371
2987
1.40
5.77
4.9
3.4
—
0.73
—
0
11
22
71
3.15
5.64
1.2
1.3
—
—
—
0
0
120
769
1.64
5.64
1.2
1.2
—
—
—
0
0
21
66
3.23
5.62
1.7
1.4
—
—
—
0
0
50
245
2.10
5.50
1.2
1.3
—
—
—
0
0
238
1789
1.45
5.37
1.6
1.7
29412229.82
35353980.34
pmol/l
0.07
204
1485
16
44
3.68
5.22
1.6
3.7
826.31
1170.57
u/ml
0.39
16
44
354
2873
1.38
5.08
3.9
3.1
—
—
—
0
0
24
87
2.81
5.07
1.7
2.5
0.66
1.20
g/24h
0.87
15
53
114
741
1.61
5.06
3.7
3.5
73.33
79.79
ng/l
0.56
99
647
241
1838
1.42
4.98
2.7
2.7
2.46
2.46
mmol/l
0.37
220
1670
16
38
4.27
4.83
1.6
1.3
1.40
5.60
%
—
5
10
101
645
1.64
4.81
2.6
2.4
15.81
6.59
ug/l
0.57
85
571
124
833
1.56
4.79
4.1
3.2
7.39
7.39
ph
0.45
78
466
747
6875
1.45
4.72
5.3
4.8
15.25
14.75
pmol/l
7.05
698
6365
36
165
2.23
4.71
5.9
2.4
83.66
90.31
%
1.72
36
159
63
358
1.82
4.56
5.6
3.4
—
—
—
0
0
118
802
1.54
4.33
4.1
3.1
1.51
1.88
mmol/l
0.52
104
694
119
817
1.52
4.17
4.7
3.8
7.35
7.36
ph
0.14
97
573
11
21
5.29
4.15
1.1
1.2
—
—
—
0
0
21
80
2.66
4.08
3.3
3.6
—
—
—
0
0
9
14
6.48
3.99
1.2
1.1
—
—
—
0
0
21
83
2.57
3.82
1.2
2.4
—
—
—
0
0
33
160
2.10
3.81
1.5
1.5
—
—
—
0
0
29
134
2.20
3.77
1.6
1.4
—
—
—
0
0
76
483
1.62
3.73
4.4
2.9
23.82
24.39
mmol/l
0.89
76
477
32
155
2.10
3.71
5.5
3.0
—
—
—
0
0
43
232
1.90
3.70
3.1
3.2
1.33
2.13
index
0.58
15
111
23
97
2.41
3.67
1.1
1.2
—
—
—
0
0
257
2084
1.32
3.46
3.4
2.2
—
—
—
0
0
48
275
1.79
3.44
3.4
3.1
300.23
263.42
mg/l
0.15
22
106
15
53
2.86
3.37
1.1
1.1
—
—
—
0
0
825
7858
1.47
3.25
6.7
5.9
2.04
1.89
mu/l
2.53
779
7317
276
3289
0.77
3.24
2.8
3.2
—
—
—
0
0
28
137
2.08
3.19
5.9
3.2
2.43
2.91
mmol/l
0.43
23
95
30
152
2.01
3.12
4.6
2.8
34.96
33.88
umol/l
0.08
25
135
27
132
2.08
3.09
1.0
1.0
—
—
—
0
0
450
3969
1.26
3.06
3.7
2.6
—
—
estimate
—
0
0
70
463
1.55
2.95
1.1
1.1
—
129.64
titre
—
0
11
18
77
2.36
2.83
1.7
1.1
90.61
110.26
pmol/l
1.01
18
77
41
671
0.59
2.77
1.6
1.8
3.35
3.47
mmol/l
0.30
28
489
6
10
6.03
2.70
1.3
1.3
—
—
—
0
0
29
512
0.55
2.60
2.3
1.8
—
—
—
0
0
9
25
3.62
2.58
2.3
1.4
—
—
—
0
0
34
193
1.79
2.57
1.2
1.4
2.50
19.30
e6/l
1.66
26
142
114
854
1.38
2.57
2.5
2.3
32.40
39.60
u/l
1.38
101
708
70
480
1.50
2.53
1.5
1.2
—
—
—
0
0
49
749
0.63
2.51
1.3
1.4
—
—
—
0
0
34
195
1.77
2.50
1.3
1.5
394.52
551.79
e6/l
0.14
27
149
65
935
0.67
2.49
1.6
1.7
—
—
—
0
0
8
21
3.83
2.46
3.1
2.6
3.88
6.23
ug/l
—
8
21
19
89
2.16
2.46
1.1
1.2
—
—
—
0
0
318
2763
1.23
2.30
3.3
2.3
—
—
—
0
0
14
60
2.35
2.22
1.4
1.2
—
—
—
0
0
17
80
2.15
2.19
2.9
3.0
12.67
12.53
index
—
9
45
11
43
2.58
2.08
2.5
3.5
14.71
16.43
%
1.08
11
43
859
8341
1.43
2.06
28.4
17.7
139.38
139.69
mmol/l
2.67
851
8186
5
145
0.34
2.02
1.2
1.5
—
—
—
0
0
26
438
0.58
2.02
1.1
1.1
—
—
—
0
0
10
38
2.65
2.01
1.1
1.3
113.10
151.61
nmol/l
—
10
38
18
91
2.00
1.96
1.4
1.2
—
—
—
0
0
9
33
2.74
1.93
5.1
2.3
—
—
—
0
0
11
46
2.41
1.85
1.4
1.2
0.56
0.50
ratio
—
5
25
101
785
1.32
1.83
1.6
1.4
—
—
—
0
0
49
336
1.48
1.83
2.0
2.9
22.19
828.51
u/ml
1.25
43
292
5
12
4.18
1.82
1.0
1.1
—
—
—
0
0
9
35
2.59
1.80
1.2
1.8
—
—
—
0
0
6
18
3.35
1.75
2.7
1.5
—
—
—
0
0
19
103
1.86
1.72
3.1
2.2
32.47
31.99
pg
0.18
19
103
19
331
0.57
1.70
1.5
1.3
—
—
—
0
0
24
141
1.72
1.69
1.3
1.3
0.75
13.22
nmol/l
0.49
24
135
857
8352
1.37
1.66
28.7
17.9
3.94
3.95
mmol/l
0.55
848
8179
15
76
1.99
1.65
1.1
1.1
—
—
—
0
0
19
105
1.83
1.64
12.1
6.3
13.72
12.29
mg/l
0.62
19
99
38
256
1.51
1.58
9.6
9.5
—
—
—
0
0
16
285
0.55
1.57
1.3
1.6
990.23
1009.88
mu/l
—
10
225
5
15
3.35
1.52
1.0
1.5
—
—
—
0
0
7
27
2.60
1.51
2.4
2.5
—
—
—
0
0
7
27
2.60
1.51
3.4
4.0
53.57
53.30
%
—
7
27
38
259
1.49
1.50
1.3
1.3
231.65
226.68
miu/ml
0.03
16
125
36
244
1.49
1.47
2.2
2.5
—
—
—
0
0
7
28
2.51
1.45
2.7
2.5
0.60
0.62
mmol/l
—
7
28
7
28
2.51
1.45
1.4
1.9
36.41
41.79
g/l
—
7
28
257
2277
1.18
1.43
1.4
1.4
—
—
—
0
0
20
118
1.71
1.42
1.3
1.3
—
—
nmol/l
—
0
0
28
181
1.56
1.41
1.3
1.4
—
—
—
0
0
90
720
1.28
1.36
3.3
2.6
6.15
6.12
ph
0.11
56
483
5
17
2.95
1.36
1.0
1.1
0.02
0.02
u/ml
—
5
17
19
305
0.62
1.30
1.1
1.2
1.57
1.60
g/l
0.22
19
305
5
18
2.79
1.28
1.4
3.7
—
—
—
0
0
11
55
2.01
1.27
1.2
1.5
13.49
10.54
umol/l
0.69
11
49
15
84
1.80
1.27
2.3
2.6
—
—
—
0
0
9
45
2.01
1.23
2.0
3.2
0.67
0.84
index
—
9
45
43
317
1.37
1.17
1.9
2.4
13.57
12.56
nmol/l
0.27
36
292
8
39
2.06
1.15
1.4
1.3
9.75
8.15
mm/h
—
8
39
5
20
2.51
1.15
1.0
1.1
—
—
—
0
0
23
152
1.53
1.09
1.1
1.1
—
—
—
0
0
21
314
0.66
1.08
1.1
1.2
0.92
0.90
g/l
0.15
21
314
31
222
1.41
1.01
1.1
1.2
—
—
—
0
0
9
51
1.77
0.94
1.4
1.3
—
—
—
0
0
594
5690
1.12
0.94
4.6
3.3
55.66
45.72
u/l
2.15
560
5365
32
237
1.36
0.89
1.2
1.1
—
—
—
0
0
8
42
1.91
0.88
1.0
1.2
—
—
—
0
0
22
152
1.46
0.88
1.1
1.1
—
—
—
0
0
35
264
1.34
0.87
5.3
3.8
1.04
1.33
mmol/l
2.27
35
259
388
3642
1.11
0.87
2.3
2.1
—
—
—
0
0
0
27
0.00
0.77
0.0
1.2
—
885.71
—
0
7
42
526
0.79
0.77
1.7
1.4
37.21
30.11
iu/l
0.59
35
451
14
91
1.55
0.75
2.9
2.6
—
—
—
0
0
7
39
1.80
0.72
2.0
1.7
—
—
—
0
0
851
8385
1.19
0.72
24.5
13.6
—
—
—
0
0
7
40
1.76
0.71
1.0
1.1
1417.29
1561.93
miu/ml
—
7
40
51
418
1.23
0.71
2.5
2.1
—
—
—
0
0
5
26
1.93
0.70
1.2
1.2
—
—
—
0
0
80
687
1.18
0.70
1.4
1.7
—
—
—
0
0
33
257
1.29
0.69
1.7
2.0
2214.21
5842.40
u/l
—
9
103
11
69
1.60
0.68
1.3
1.8
1.83
1.92
u/field
—
6
38
11
69
1.60
0.68
1.2
1.1
—
1.04
—
0
8
44
360
1.23
0.64
1.5
1.6
5.82
12.51
u/ml
—
5
72
12
79
1.53
0.62
1.3
1.2
—
—
—
0
0
8
51
1.57
0.60
1.3
1.4
95.25
72.25
umol/l
—
8
51
890
8823
1.24
0.57
48.4
23.7
4.35
4.44
e12/l
8.02
885
8632
890
8823
1.24
0.57
48.4
23.7
6.59
6.60
e9/l
0.06
885
8631
9
60
1.50
0.54
1.1
1.7
59.33
108.37
ng/l
—
9
60
13
91
1.43
0.53
1.2
1.6
—
—
—
0
0
13
92
1.42
0.50
1.5
1.1
—
—
—
0
0
19
245
0.77
0.48
1.1
1.3
—
—
—
0
0
771
7826
0.91
0.47
5.7
6.3
38.07
38.92
mmol/mol
1.05
733
7354
40
337
1.20
0.47
2.0
1.5
0.25
0.35
mg/l
0.86
19
139
20
155
1.30
0.47
2.4
1.9
—
—
—
0
0
76
853
0.88
0.47
1.9
1.4
—
—
—
0
0
68
601
1.14
0.45
2.1
3.3
4.27
4.48
pmol/l
1.11
58
529
829
8192
1.12
0.45
5.0
5.2
4.62
4.77
mmol/l
4.24
785
7646
10
69
1.45
0.44
1.4
1.6
—
—
—
0
0
51
443
1.16
0.43
4.0
3.4
1.02
1.02
ratio
0.38
46
409
101
919
1.11
0.43
2.4
4.1
4.10
23.43
ug/l
1.47
84
738
5
31
1.62
0.43
1.0
1.7
67.80
76.97
nmol/24h
—
5
31
18
228
0.79
0.41
1.1
1.3
—
—
—
0
0
24
195
1.24
0.41
2.0
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
38.76
—
0
18
5
35
1.43
0.39
2.0
2.3
40.12
51.95
umol/l
—
5
28
9
67
1.35
0.38
1.1
1.6
6.50
7.84
ug/l
—
9
56
32
271
1.19
0.37
1.3
1.2
—
—
—
0
0
20
245
0.81
0.36
1.1
1.3
—
—
—
0
0
20
245
0.81
0.36
1.1
1.3
—
—
—
0
0
40
348
1.16
0.35
1.0
1.1
—
—
—
0
0
20
244
0.82
0.35
1.1
1.3
—
—
—
0
0
11
84
1.31
0.30
3.7
2.5
—
—
—
0
0
10
76
1.32
0.28
1.2
1.1
—
—
—
0
0
76
703
1.09
0.26
1.2
1.2
133.27
141.59
u/ml
0.06
23
287
823
8163
1.08
0.26
4.9
5.1
1.60
1.54
mmol/l
2.69
775
7574
837
8312
1.07
0.24
5.5
6.0
2.61
2.77
mmol/l
6.49
791
7742
5
41
1.22
0.22
1.2
1.5
97.60
157.99
mmol/24h
—
5
41
17
199
0.85
0.22
4.6
4.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
53.18
—
0
11
0
11
0.00
0.21
0.0
2.1
—
119.82
—
0
11
0
10
0.00
0.21
0.0
5.8
—
7.60
—
0
10
12
98
1.23
0.21
1.2
1.7
16.33
26.41
ng/l
1.66
12
98
0
14
0.00
0.20
0.0
3.6
—
—
—
0
0
13
154
0.84
0.19
1.0
1.0
0.93
3.30
u/ml
—
7
80
19
166
1.15
0.18
1.2
1.5
—
—
—
0
0
20
176
1.14
0.17
1.1
1.1
0.61
1.57
u/ml
1.51
13
89
31
283
1.10
0.16
1.7
1.8
330.92
291.36
mu/l
0.35
26
257
25
274
0.91
0.14
1.6
2.0
3.11
24.47
iu/l
—
9
115
17
191
0.89
0.14
1.1
1.3
—
—
—
0
0
15
170
0.88
0.13
2.1
2.3
29.47
84.99
ug/min
—
7
100
13
149
0.87
0.13
1.0
1.0
1.35
1.64
u/ml
—
6
59
785
7809
1.04
0.12
4.2
4.3
1.16
1.27
mmol/l
6.20
737
7171
65
621
1.05
0.11
3.2
3.1
0.61
0.73
ug/l
0.84
40
383
116
1128
1.03
0.10
1.2
1.3
—
—
—
0
0
5
44
1.14
0.10
1.2
1.6
—
—
—
0
0
296
2920
1.02
0.09
3.4
3.3
6.24
6.97
mmol/l
2.52
248
2470
15
136
1.10
0.08
1.2
1.2
—
—
—
0
0
5
64
0.78
0.08
1.0
1.1
—
5.83
—
0
16
12
133
0.90
0.07
1.3
1.2
—
—
—
0
0
6
70
0.86
0.07
1.2
1.0
—
—
—
0
0
13
143
0.91
0.07
1.2
1.2
—
—
—
0
0
9
88
1.02
0.07
1.1
1.5
—
—
—
0
0
373
3702
1.01
0.05
1.9
1.9
1.25
1.34
mmol/l
1.82
311
3142
286
2835
1.01
0.05
4.0
4.0
17.82
7.41
mg/mmol
1.04
161
1644
800
7984
1.02
0.03
4.9
5.2
5.59
5.87
mmol/l
11.32
747
7343
63
643
0.98
0.03
1.1
1.3
—
—
—
0
0
103
1043
0.99
0.03
5.5
5.0
2.36
2.21
ug/l
0.10
93
932
10
108
0.93
0.03
1.0
1.3
—
—
—
0
0
13
124
1.05
0.00
1.1
1.0
1.09
5.58
u/ml
—
6
44
279
2787
1.00
0.00
3.4
3.4
71.05
37.09
mg/l
0.98
156
1654
13
129
1.01
0.00
1.2
1.0
0.27
2.88
u/ml
—
6
56
18
175
1.03
0.00
5.0
1.6
0.83
0.86
nmol/l
0.10
18
146
13
125
1.04
0.00
1.1
1.1
—
—
—
0
0
15
145
1.04
0.00
1.1
1.0
0.32
1.80
u/ml
—
8
65
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
2.60
—
0
5
0
6
0.00
-0.00
0.0
2.0
—
256.82
—
0
6
5
51
0.98
-0.00
1.2
1.3
1.34
1.30
promille
—
5
40
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.0
1115.00
742.78
ng/l
—
5
37
0
5
0.00
-0.00
0.0
1.2
—
30.86
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
0.52
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
10
100
1.00
-0.00
1.1
1.1
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.0
422.20
334.79
ng/l
—
5
39
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
17
170
1.00
-0.00
3.6
3.7
23.78
22.31
mg/l
—
9
114
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: SYSTSCLE_ICD10 – Systemic sclerosis, icd10

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).