No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
179 |
4. Check minimum number of eventsNone |
179 |
5. Include endpointsNone |
179 |
6. Filter based on genotype QC (FinnGen only) |
162 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Progressive systemic sclerosis
based on the number of shared cases.
Similar with more cases:
- Systemic sclerosis, icd10
- Systemic sclerosis
- Systemic sclerosis (FG)
- Systemic connective tissue disorders
- Autoimmune diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 162 | 133 | 29 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.01 |
| Median age at first event (years) | 54.81 | 52.75 | 64.23 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 168
- Matched controls
- 1680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M34.0
ICD-10 Finland
Progressive systemic sclerosis
+∞
243.0
168
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
38.4
132.3
124
115
C08CA05
ATC
nifedipine; systemic
42.4
131.5
95
50
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
+∞
109.8
93
*
P01BA02
ATC
hydroxychloroquine; oral
21.0
91.4
95
98
M34.1
ICD-10 Finland
CR(E)ST syndrome
267.7
78.7
75
5
L04AX01
ATC
azathioprine; systemic
26.5
63.9
48
25
L04AX03
ATC
methotrexate; systemic
13.0
59.8
77
103
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
11.6
43.3
53
64
M34.8
ICD-10 Finland
Other forms of systemic sclerosis
+∞
38.0
35
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
51.9
36.5
43
11
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
11.2
35.7
43
50
L04AA06
ATC
mycophenolic acid; systemic
46.1
34.8
42
12
XG410
NOMESCO Finland
Flow-volume spirometry
12.2
33.4
37
38
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
12.2
30.2
33
33
XX9XE
NOMESCO Finland
Other ultrasound examination
78.4
29.1
32
5
I73.0
ICD-10 Finland
Raynaud syndrome
33.5
28.6
37
14
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
6.8
27.3
54
110
M34
ICD-10 Finland
Systemic sclerosis
305.4
26.5
26
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.4
26.4
104
387
G04BE03
ATC
sildenafil; oral
69.5
25.9
29
5
XPX04
NOMESCO Finland
Angioscopy
291.6
25.4
25
*
L88
ICPC
Rheumatoid/seropositive arthritis
9.1
24.3
33
44
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.2
23.4
134
653
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
6.4
21.8
43
86
L04AA01
ATC
[U] ciclosporin
58.3
21.8
25
5
GD1AD
NOMESCO Finland
Thorax CT examination
7.6
21.5
34
54
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
26.5
19.8
27
12
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
6.3
19.2
37
72
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
50.3
18.7
22
5
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
16.3
18.6
30
22
H02AB06
ATC
prednisolone; systemic
4.7
18.0
127
670
TPH04
NOMESCO Finland
Cathetrisation of vein
4.1
17.5
69
242
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
4.2
17.1
62
204
J99.1*M34.8
ICD-10 Finland
Respiratory disorders in systemic: sclerosis
+∞
17.0
16
*
L94.0
ICD-10 Finland
Localized scleroderma [morphea]
53.2
16.4
19
*
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
13.2
16.0
28
25
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
175.7
15.8
16
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
13.8
15.7
27
23
Z01.8
ICD-10 Finland
Other specified special examinations
3.8
15.5
69
260
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.7
15.0
74
297
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
5.4
14.8
33
73
J01FF01
ATC
clindamycin; systemic
3.5
14.2
79
341
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
4.6
14.1
39
103
SPAT1148
SPAT
Treatment of chronic ulcer or burn
4.3
14.1
44
128
C02KX01
ATC
bosentan; oral
+∞
13.7
13
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.6
13.6
38
101
L01BA01
ATC
methotrexate; systemic
11.5
13.5
25
25
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
5.4
13.4
29
62
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.4
13.3
104
546
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.8
13.1
34
85
L04AD01
ATC
ciclosporin; systemic
17.3
13.0
20
13
H02AB07
ATC
prednisone; oral
3.9
12.8
47
153
L95
ICPC
Osteoporosis
5.3
12.7
28
61
M05BX04
ATC
denosumab; parenteral
4.7
12.0
31
77
C08CA02
ATC
felodipine; oral
4.5
11.9
33
87
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
15.1
11.8
19
14
M01CC01
ATC
penicillamine; oral
+∞
11.6
11
*
I27.0
ICD-10 Finland
Primary pulmonary hypertension
+∞
11.6
11
*
7101A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic sclerosis[SCLERODERMA]
+∞
11.6
11
*
QC6S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in hand
128.4
11.6
12
*
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
128.4
11.6
12
*
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
13.2
11.2
19
16
ZX120
NOMESCO Finland
Intravenous
4.0
11.0
37
112
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.5
10.8
29
74
M05BA04
ATC
alendronic acid; oral
3.8
10.7
39
125
M35.1
ICD-10 Finland
Other overlap syndromes
117.0
10.5
11
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
4.1
10.5
33
95
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
12.4
10.3
18
16
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.3
10.2
47
175
A02BC01
ATC
omeprazole; systemic
2.9
9.8
71
342
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.8
9.8
34
105
E0000UV, ,
ATC
2.8
9.8
99
568
R06.0
ICD-10 Finland
Dyspnoea
2.8
9.7
73
358
G73.7*M34.8
ICD-10 Finland
Myopathy in scleroderma
+∞
9.5
9
*
R4120
NOMESCO Finland
Occupational therapy
4.5
9.4
25
63
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.9
9.4
22
50
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
14.8
9.4
15
11
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
16.8
9.2
14
9
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
25.7
9.0
12
5
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.2
9.0
26
70
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
4.7
9.0
22
52
TGC00
NOMESCO Finland
Bronchial lavation
8.4
8.9
19
25
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
4.9
8.9
21
48
M05BA07
ATC
risedronic acid; oral
7.1
8.8
21
33
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
8.8
63
299
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
21.4
8.6
12
6
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.9
8.5
27
78
M35.8
ICD-10 Finland
Other specified systemic involvement of connective tissue
+∞
8.4
8
*
C02KX04
ATC
macitentan; oral
+∞
8.4
8
*
RT172, ,
NOMESCO Finland
+∞
8.4
8
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
7.5
8.3
19
28
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.6
8.3
21
51
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.5
8.3
32
106
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.1
8.1
24
66
M13.9
ICD-10 Finland
Arthritis, unspecified
4.1
7.9
23
62
C03DA01
ATC
spironolactone; oral
3.2
7.8
36
133
L99
ICPC
Musculoskeletal disease other
9.6
7.7
15
17
C03CA01
ATC
furosemide; systemic
2.5
7.7
72
385
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.0
7.6
23
64
UJF32
NOMESCO Finland
Coloscopy
2.5
7.5
65
335
RT160, ,
NOMESCO Finland
83.6
7.5
8
*
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
9.4
7.2
14
16
E000001, ,
ATC
2.7
7.1
48
218
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
8.9
7.0
14
17
K74.3
ICD-10 Finland
Primary biliary cirrhosis
41.8
6.8
8
*
R13
ICD-10 Finland
Dysphagia
3.6
6.7
24
75
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.2
6.6
28
98
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
15.1
6.5
10
7
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
72.5
6.5
7
*
RT271, ,
NOMESCO Finland
72.5
6.5
7
*
R4180
NOMESCO Finland
Podiatric therapy
11.7
6.4
11
10
C02DE02, ,
ATC
11.7
6.4
11
10
M81.4
ICD-10 Finland
Drug-induced osteoporosis
27.8
6.3
8
*
XQ860
NOMESCO Finland
Laser Doppler measurement/scan of capillary perfusion
+∞
6.3
6
*
J01MA12
ATC
levofloxacin; systemic
2.6
6.2
45
210
J96.1
ICD-10 Finland
Chronic respiratory failure
9.1
6.2
12
14
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
13.2
6.2
10
8
M43.1
ICD-10 Finland
Spondylolisthesis
4.2
6.2
17
44
M43.0
ICD-10 Finland
Spondylolysis
10.6
6.1
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
66
81
12.77
54.08
3.3
1.8
11.17
4.18
iu/ml
0.84
26
22
53
58
12.89
46.55
1.6
1.3
1.37
2.71
u/ml
—
14
9
56
68
11.85
45.68
1.7
1.3
7.98
0.32
u/ml
—
6
5
52
59
12.32
44.43
1.6
1.3
7.74
2.90
u/ml
0.48
19
12
47
59
10.67
36.94
3.3
1.5
1.07
1.15
g/l
0.71
47
59
119
523
5.37
23.79
7.3
3.4
805.81
954.39
ng/l
0.51
110
441
31
55
6.69
17.53
2.4
2.9
—
—
—
0
0
21
7
33.97
16.56
3.4
1.0
8.32
10.76
ug/l
—
21
7
143
866
5.38
15.81
8.8
4.2
0.00
9.28
estimate
0.50
26
175
142
860
5.21
15.57
8.8
4.1
0.00
0.00
estimate
-0.00
26
166
142
874
5.04
14.88
9.0
4.2
0.00
0.00
estimate
-0.00
26
162
23
20
13.12
13.29
1.2
1.2
—
—
—
0
0
21
35
6.71
12.46
2.6
1.2
—
—
—
0
0
23
44
5.90
11.91
2.1
1.6
125.00
125.83
g/l
—
10
30
83
411
3.01
11.20
4.7
2.2
3.55
3.19
mg/l
0.54
78
357
100
553
3.00
10.96
8.1
3.3
—
—
—
0
0
79
385
2.99
10.91
8.6
4.4
1.01
1.02
kg/l
1.03
61
252
80
409
2.83
9.89
6.8
2.9
344.54
330.93
umol/l
0.49
70
346
128
840
3.20
9.81
12.7
7.5
1.22
1.22
mmol/l
0.23
117
720
45
170
3.25
9.52
1.9
2.0
339.23
388.38
nmol/l
0.77
40
162
35
120
3.42
8.59
2.6
1.7
—
—
—
0
0
117
763
2.76
8.48
11.0
6.7
1.21
1.22
mmol/l
0.67
112
698
18
38
5.19
8.33
2.7
1.6
—
—
—
0
0
20
47
4.70
8.19
3.0
1.8
—
—
—
0
0
11
5
23.38
8.12
2.6
1.0
—
—
—
0
0
13
10
13.96
8.02
1.2
1.0
—
—
—
0
0
154
1187
4.57
8.00
18.2
4.8
15.07
12.38
mm/h
1.75
154
1095
15
16
10.17
7.96
1.3
1.2
—
—
—
0
0
15
16
10.17
7.96
1.3
1.3
—
—
—
0
0
26
77
3.81
7.90
7.3
3.9
1.34
1.90
mmol/l
0.33
19
58
58
277
2.67
7.87
4.1
3.0
0.53
1.05
e6/l
2.20
42
147
85
488
2.50
7.85
9.4
4.3
0.00
0.00
estimate
-0.00
26
162
20
49
4.50
7.78
7.3
1.9
24.16
24.39
mmol/l
0.08
20
49
64
323
2.59
7.75
5.0
3.8
358.19
134.22
ng/l
0.54
52
261
15
17
9.57
7.73
1.3
1.2
—
—
—
0
0
15
17
9.57
7.73
1.3
1.2
—
—
—
0
0
19
45
4.63
7.70
3.1
1.7
—
—
—
0
0
103
650
2.51
7.69
8.9
4.1
0.00
0.00
estimate
-0.00
24
134
43
179
2.88
7.56
2.3
5.2
272.49
253.46
u/l
0.36
43
168
17
38
4.86
7.36
1.1
1.1
—
—
—
0
0
79
452
2.41
7.19
6.2
3.2
0.07
0.37
e6/l
4.49
67
324
15
20
8.12
7.07
1.3
1.2
—
—
—
0
0
14
17
8.87
6.98
3.1
1.4
—
—
—
0
0
52
256
2.49
6.47
3.4
2.0
—
—
—
0
0
16
28
6.20
6.33
3.1
2.0
—
—
—
0
0
17
33
5.61
6.21
2.8
1.6
—
—
—
0
0
10
8
13.19
6.16
1.4
1.1
146.80
173.84
u/l
—
10
8
42
191
2.60
6.14
2.8
1.9
—
—
—
0
0
17
48
3.83
5.48
2.5
5.2
4.38
3.26
ratio
0.15
12
25
8
5
16.69
5.46
1.1
1.0
—
—
—
0
0
75
464
2.11
5.25
7.3
3.5
0.00
0.00
estimate
-0.00
25
130
38
177
2.48
5.23
2.8
2.0
—
—
—
0
0
14
27
5.56
5.21
2.3
1.7
—
—
—
0
0
15
33
4.89
5.01
23.8
6.5
99.50
168.33
iu/ml
—
6
6
15
34
4.74
4.88
2.3
1.6
—
—
—
0
0
11
17
6.84
4.86
3.9
1.5
—
—
—
0
0
90
609
2.03
4.83
3.7
3.3
2.37
2.37
mmol/l
0.00
85
552
12
22
5.79
4.70
1.2
1.2
—
209.90
—
0
6
12
22
5.79
4.70
3.3
1.6
—
—
—
0
0
14
33
4.53
4.44
6.9
2.4
7.44
7.86
kpa
0.52
14
33
18
61
3.18
4.44
1.3
1.5
267.10
282.12
ug/g
—
10
36
79
523
1.96
4.39
3.1
2.6
58.28
55.72
u/l
0.31
72
488
16
54
3.17
3.97
2.7
1.9
1.83
1.54
mg/l
0.69
16
47
43
239
2.07
3.83
5.5
3.3
4.02
3.61
e6/l
0.08
27
108
46
263
2.03
3.80
7.2
3.6
0.82
0.80
mmol/l
0.43
41
248
12
30
4.23
3.68
1.0
1.6
—
—
—
0
0
29
140
2.29
3.65
3.3
2.2
65.55
60.24
ml/min/173m2
0.22
11
51
17
63
2.89
3.61
1.3
1.3
—
—
—
0
0
8
13
6.40
3.54
1.4
4.7
531.62
932.15
mg
—
8
13
6
6
10.31
3.52
3.5
1.5
—
—
—
0
0
6
6
10.31
3.52
3.5
1.5
—
—
—
0
0
10
22
4.76
3.49
1.5
1.2
8.40
1.38
u/ml
—
5
8
13
38
3.62
3.40
2.2
1.2
—
—
—
0
0
6
7
8.83
3.29
3.7
1.6
—
—
—
0
0
7
11
6.58
3.22
3.1
1.6
—
—
—
0
0
14
50
2.96
3.17
6.6
4.8
24.06
25.49
mmol/l
0.91
14
50
96
728
1.74
3.10
3.3
2.9
—
—
estimate
—
0
0
6
8
7.72
3.08
1.8
1.1
17.83
12.75
u/l
—
6
8
11
31
3.72
3.05
4.5
2.4
15.72
15.89
%
0.06
11
31
7
12
6.03
3.05
2.9
1.8
0.64
0.36
e9/l
—
7
12
8
17
4.88
2.95
1.1
1.0
—
—
—
0
0
6
9
6.86
2.89
1.0
5.0
81.50
271.78
nmol/l
—
6
9
8
18
4.61
2.83
5.1
5.0
—
—
—
0
0
19
85
2.39
2.83
1.6
1.3
—
—
—
0
0
7
14
5.17
2.76
1.0
1.0
—
—
—
0
0
6
10
6.17
2.72
2.3
1.4
—
—
—
0
0
38
229
1.85
2.63
13.4
6.3
102.89
103.79
mmol/l
0.53
38
229
11
36
3.20
2.62
1.6
1.4
—
—
—
0
0
5
7
7.32
2.56
1.2
1.0
—
—
—
0
0
44
280
1.77
2.55
1.7
1.7
1225.26
1260.22
nmol/l
0.10
36
204
20
96
2.23
2.55
15.1
9.2
22.96
24.54
mmol/l
1.14
20
96
7
17
4.25
2.38
2.3
2.3
—
—
—
0
0
7
17
4.25
2.38
1.4
1.0
—
—
—
0
0
10
34
3.06
2.32
2.2
1.6
—
—
—
0
0
7
18
4.01
2.27
1.9
2.0
—
—
—
0
0
7
18
4.01
2.27
1.9
2.0
—
—
—
0
0
7
18
4.01
2.27
1.9
2.0
—
—
—
0
0
7
18
4.01
2.27
2.3
2.2
—
—
—
0
0
94
749
1.58
2.21
2.4
2.1
100.22
99.70
pmol/l
0.04
61
351
6
14
4.40
2.17
1.0
1.1
—
—
—
0
0
5
10
5.11
2.08
2.0
2.1
—
—
—
0
0
5
10
5.11
2.08
2.0
2.1
—
—
—
0
0
5
10
5.11
2.08
2.0
2.1
—
—
—
0
0
5
10
5.11
2.08
2.0
2.1
—
—
—
0
0
19
98
2.06
2.05
14.6
7.6
25.38
24.76
mmol/l
0.21
19
98
8
26
3.18
2.04
1.1
1.3
—
—
—
0
0
55
393
1.59
2.03
2.7
2.5
—
—
—
0
0
19
99
2.04
2.00
6.0
3.0
24.25
24.72
mmol/l
0.29
19
99
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
10
39
2.66
1.98
2.2
2.7
0.20
0.43
iu/ml
—
5
24
7
22
3.27
1.90
1.4
1.1
—
—
—
0
0
57
419
1.55
1.84
1.4
1.3
0.43
1.65
u/ml
—
10
115
48
340
1.58
1.82
1.3
1.4
74.93
37.92
iu/ml
0.37
15
121
8
29
2.84
1.81
1.0
2.1
—
—
—
0
0
19
103
1.95
1.80
17.7
9.0
1.07
1.44
%
1.34
19
103
13
61
2.23
1.76
1.1
1.4
—
—
—
0
0
5
13
3.93
1.72
1.2
1.0
—
—
—
0
0
78
624
1.47
1.65
7.9
4.1
25.31
122.89
ng/l
0.56
59
451
18
99
1.92
1.65
18.3
9.3
0.56
0.66
%
0.46
18
99
7
26
2.76
1.60
1.3
1.6
—
—
—
0
0
7
26
2.76
1.60
1.3
1.6
—
—
—
0
0
8
33
2.49
1.56
1.9
1.9
6.57
7.28
pmol/l
—
8
33
12
58
2.15
1.53
3.7
2.1
—
—
—
0
0
5
16
3.19
1.45
2.2
2.6
—
—
—
0
0
6
22
2.79
1.45
1.8
1.5
5.53
170.98
u/ml
—
6
22
29
193
1.61
1.42
11.5
6.6
—
—
—
0
0
16
90
1.86
1.38
1.6
3.4
4.08
4.50
pmol/l
1.01
16
75
6
23
2.67
1.38
1.8
1.4
—
—
—
0
0
11
54
2.11
1.36
3.3
1.8
—
—
—
0
0
156
1466
1.90
1.33
45.4
16.8
18.92
21.30
mg/l
0.62
148
1195
12
63
1.97
1.26
4.4
2.1
0.00
0.00
g/l
-0.00
12
56
10
49
2.11
1.24
2.0
1.4
—
—
—
0
0
5
20
2.54
1.16
1.4
1.4
—
—
—
0
0
98
854
1.35
1.12
3.4
2.8
—
—
—
0
0
5
21
2.42
1.10
1.2
1.8
—
—
—
0
0
22
147
1.57
1.07
2.5
1.5
—
—
—
0
0
5
22
2.31
1.04
1.2
1.8
—
—
—
0
0
5
23
2.21
0.98
1.2
1.2
0.22
0.19
nmol/l
—
5
15
0
31
0.00
0.97
0.0
1.6
—
973.07
—
0
25
56
672
0.75
0.96
2.0
2.0
1.38
1.30
mmol/l
0.44
45
560
8
47
1.74
0.82
1.0
2.0
—
—
—
0
0
66
563
1.28
0.81
3.7
3.7
20.96
7.35
mg/mmol
0.58
38
322
15
100
1.55
0.76
1.5
1.3
—
47.97
—
0
8
11
69
1.64
0.70
2.4
1.5
—
—
—
0
0
8
50
1.63
0.62
1.6
1.4
—
—
—
0
0
0
20
0.00
0.61
0.0
1.8
—
52.67
—
0
14
46
388
1.26
0.60
2.4
1.7
1.09
1.22
mg/l
0.12
39
311
0
22
0.00
0.60
0.0
1.1
—
1.18
—
0
13
38
315
1.27
0.58
1.3
1.3
1.29
13.47
u/ml
2.84
12
123
12
82
1.50
0.56
1.6
1.4
—
—
—
0
0
141
1465
0.77
0.55
5.3
5.5
5.70
5.95
mmol/l
1.28
136
1347
134
1399
0.79
0.53
4.6
4.5
1.22
1.25
mmol/l
0.26
125
1265
129
1223
1.24
0.51
46.3
21.0
14.79
13.73
%
11.88
129
1214
11
76
1.48
0.49
1.7
3.0
23.00
2281.38
u/ml
0.68
11
67
145
1496
0.78
0.46
5.8
6.3
2.58
2.71
mmol/l
0.94
137
1371
20
158
1.30
0.44
6.5
3.6
—
—
—
0
0
129
1230
1.21
0.44
5.5
4.9
15.36
14.96
pmol/l
1.07
123
1118
8
59
1.37
0.41
1.3
1.2
—
—
—
0
0
12
88
1.39
0.41
2.1
1.8
—
—
—
0
0
8
60
1.35
0.41
1.3
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.4
—
0.95
—
0
6
0
17
0.00
0.41
0.0
1.4
—
0.88
—
0
6
0
17
0.00
0.41
0.0
1.4
—
1.35
—
0
6
39
338
1.20
0.40
2.0
1.7
422.90
496.70
pmol/l
0.85
34
272
6
41
1.48
0.36
1.0
1.1
—
14.13
—
0
6
125
1204
1.15
0.29
50.4
22.2
325.16
330.79
g/l
9.20
125
1204
17
203
0.82
0.27
5.2
5.1
35.18
32.56
%
0.47
11
124
144
1471
0.85
0.24
5.3
5.4
4.58
4.71
mmol/l
0.71
137
1350
5
38
1.33
0.23
1.0
1.1
—
7.73
—
0
6
8
102
0.77
0.22
1.1
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
22
248
0.87
0.19
1.5
1.5
—
—
—
0
0
139
1418
0.89
0.19
7.5
6.1
2.05
1.94
mu/l
0.58
134
1306
27
299
0.88
0.19
1.5
1.4
—
—
—
0
0
144
1465
0.88
0.17
5.1
5.3
1.56
1.57
mmol/l
0.06
135
1339
157
1550
1.20
0.16
50.9
22.3
75.26
73.22
umol/l
0.41
157
1532
18
164
1.11
0.10
3.4
4.6
26.42
20.95
%
—
9
91
5
43
1.17
0.10
2.0
1.4
—
—
—
0
0
6
53
1.14
0.09
2.2
2.0
—
—
—
0
0
6
58
1.04
0.08
1.2
1.4
40.27
31.31
iu/l
—
6
52
8
91
0.87
0.07
1.1
1.8
—
—
—
0
0
8
92
0.86
0.07
1.0
1.0
—
—
—
0
0
157
1580
0.90
0.05
64.0
25.8
128.15
132.80
g/l
3.94
157
1563
157
1580
0.90
0.05
63.0
25.6
4.37
4.42
e12/l
0.72
157
1546
157
1580
0.90
0.05
64.5
26.0
39.42
39.88
%
0.74
157
1564
157
1579
0.91
0.04
62.7
25.5
90.93
91.38
fl
0.59
157
1564
157
1579
0.91
0.04
63.3
25.6
266.05
256.48
e9/l
0.89
157
1554
10
97
1.03
0.00
5.0
2.4
0.66
0.61
%
—
10
97
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.0
—
4.48
—
0
8
10
100
1.00
-0.00
5.0
2.4
0.76
1.18
%
—
10
100
0
8
0.00
-0.00
0.0
1.5
—
42.69
—
0
8
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.0
—
10.69
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: M13_PROGRESSIVE_SYSTEMIC_SCLEROSIS – Progressive systemic sclerosis
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).