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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Systemic sclerosis induced by drugs and chemicals

SYSTEMIC_SCLEROSIS_INDUCED_DRUGS_CHEMIC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M34.2#

1 out of 7 registries used, show all original rules.

10

4. Check minimum number of events

None

10

5. Include endpoints

None

10

6. Filter based on genotype QC (FinnGen only)

9

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 46 28 17
Only index persons 43 26 17
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 57.05 55.83 58.34
Only index persons 56.57 55.41 58.34

-FinnGen-

Key figures

All Female Male
Number of individuals 9 6 -
Unadjusted period prevalence (%) 0.00 0.00 -
Median age at first event (years) 50.59 48.97 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
9
74
+∞
0.46
3.7
4.9
4.24
4.72
mmol/l
—
9
69
0
10
0.00
0.23
0.0
1.6
—
67.01
—
0
10
9
80
+∞
0.23
34.8
13.3
—
—
—
0
0
0
12
0.00
0.23
0.0
8.3
—
2.06
—
0
12
0
5
0.00
0.00
0.0
5.8
—
1.89
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.2
—
5.42
—
0
9
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
6.88
—
0
6
0
6
0.00
-0.00
0.0
4.7
—
14.00
—
0
6
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
25.03
—
0
6
9
83
+∞
-0.00
50.8
26.9
94.23
91.03
fl
—
9
83
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
83
+∞
-0.00
54.4
27.0
131.00
134.04
g/l
—
9
83
9
83
+∞
-0.00
50.6
26.9
30.89
30.23
pg
—
9
83

Mortality – FinRegistry

Association

Association between endpoint SYSTEMIC_SCLEROSIS_INDUCED_DRUGS_CHEMIC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have SYSTEMIC_SCLEROSIS_INDUCED_DRUGS_CHEMIC.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: SYSTEMIC_SCLEROSIS_INDUCED_DRUGS_CHEMIC – Systemic sclerosis induced by drugs and chemicals

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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