anus disease: A non-neoplastic or neoplastic disorder that affects the anal canal or anal margin. Representative examples of non-neoplastic disorders include hemorrhoids and anal ulcer. Representative examples of neoplastic disorders include carcinoma, lymphoma, and melanoma. [database_cross_reference: NCIT:C26695]
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly females |
313377 |
2. Check conditionsNone |
313377 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1242 |
4. Check minimum number of eventsNone |
1242 |
5. Include endpointsNone |
1242 |
6. Filter based on genotype QC (FinnGen only) |
1122 |
Control definitions (FinnGen only)
- Control exclude
- N14_FEMALEGENINF
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Ulcer of vagina/vulva
based on the number of shared cases.
Similar with more cases:
- Inflammatory diseases of female pelvic organs
- Genitourinary diseases
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5605 | 5605 | - |
| Only index persons | 5168 | 5168 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.16 | - |
| Only index persons | 0.19 | 0.19 | - |
| Median age at first event (years) | |||
| Whole population | - | 46.23 | - |
| Only index persons | - | 48.21 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1122 | 1122 | - |
| Unadjusted period prevalence (%) | 0.40 | 0.40 | - |
| Median age at first event (years) | 53.61 | 53.61 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1168
- Matched controls
- 11680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N76.5
ICD-10 Finland
Ulceration of vagina
309.4
307.7
363
17
N76.6
ICD-10 Finland
Ulceration of vulva
944.2
307.7
843
32
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
25.3
307.7
289
150
ULA02
NOMESCO Finland
Kolposcopy
6.3
181.7
404
908
LEB00
NOMESCO Finland
Biopsy of vagina
15.1
130.5
119
87
D07AD01
ATC
clobetasol; topical
4.1
105.7
392
1275
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
7.2
98.5
157
245
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
3.6
75.0
322
1127
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.9
70.0
631
3356
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
14.2
66.0
61
45
J02AC01
ATC
fluconazole; systemic
2.5
51.1
689
4243
N76.0
ICD-10 Finland
Acute vaginitis
3.7
50.4
180
548
N76.3
ICD-10 Finland
Subacute and chronic vulvitis
12.8
48.0
47
38
N76.2
ICD-10 Finland
Acute vulvitis
15.1
46.1
41
28
N76.1
ICD-10 Finland
Subacute and chronic vaginitis
6.1
44.7
81
142
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
6.3
41.9
73
123
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.5
38.5
325
1577
N76.8
ICD-10 Finland
Other specified inflammation of vagina and vulva
7.8
36.3
51
68
P01AB01
ATC
metronidazole; oral, rectal
2.2
35.8
577
3640
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
5.8
35.3
66
119
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.5
35.2
266
1220
L29.2
ICD-10 Finland
Pruritus vulvae
5.2
33.5
71
144
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
10.3
32.8
37
37
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
32.7
552
3507
N77.1*B37.3
ICD-10 Finland
Candidiasis of vulva and vagina
5.4
32.2
65
126
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.1
31.9
745
5315
J05AB11
ATC
valaciclovir; oral
2.4
30.1
242
1134
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.1
29.6
424
2511
E0000UV, ,
ATC
2.0
29.0
606
4099
L43.9
ICD-10 Finland
Lichen planus, unspecified
6.0
28.5
51
88
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
27.9
269
1361
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
7.3
27.7
41
58
X15
ICPC
Vaginal symptom/complaint other
3.1
27.4
126
443
N90.8
ICD-10 Finland
Other specified noninflammatory disorders of vulva and perineum
6.6
25.8
42
66
D07AC01
ATC
betamethasone; topical
1.9
24.9
470
3024
LCA06
NOMESCO Finland
Biopsy of endometrium
2.3
24.4
218
1063
N94.1
ICD-10 Finland
Dyspareunia
5.0
23.8
52
108
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
2.6
22.9
143
591
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
23.5
22.7
32
14
A02BC02
ATC
pantoprazole; systemic
1.9
22.2
809
6330
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
22.1
413
2627
J01DB01
ATC
cefalexin; oral
2.3
21.9
1010
8567
G01AA10
ATC
clindamycin; vaginal
2.1
21.7
253
1365
LFC00
NOMESCO Finland
Partial excision of vulva
19.9
20.9
31
16
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
7.8
20.9
29
38
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.2
19.9
204
1045
UKC02
NOMESCO Finland
Cystoscopy
2.5
19.3
133
575
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
18.8
348
2186
C51.01
ICD-10 Finland
Squamous cell carcinoma of the labium majus
71.1
18.8
21
*
X16
ICPC
Vulval symptom/complaint
4.1
18.5
51
128
H02AB06
ATC
prednisolone; systemic
1.7
18.1
548
3958
8070/3-C51.9
ICD-O-3
Squamous cell carcinoma, NOS, of vulva, NOS
67.7
17.8
20
*
J05AB01
ATC
aciclovir; systemic
1.8
17.6
315
1952
N30.0
ICD-10 Finland
Acute cystitis
1.9
17.5
299
1825
U07
ICPC
Urine symptom/complaint other
2.3
17.1
133
606
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
16.8
292
1789
J01CA08
ATC
pivmecillinam; oral
1.7
16.8
686
5332
J01MA02
ATC
ciprofloxacin; systemic
1.7
16.6
405
2741
A02BC05
ATC
esomeprazole; systemic
1.7
16.5
479
3394
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.4
16.4
123
552
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
2.1
16.3
177
923
B37.3
ICD-10 Finland
Candidiasis of vulva and vagina
4.0
16.0
46
119
M79.6
ICD-10 Finland
Pain in limb
1.7
15.7
564
4212
J01EA01
ATC
trimethoprim; systemic
1.7
15.6
387
2620
N89.8
ICD-10 Finland
Other specified noninflammatory disorders of vagina
5.8
15.4
28
49
N03AX16
ATC
[U] pregabalin
1.8
14.9
261
1595
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.7
14.9
323
2103
N81.1
ICD-10 Finland
Cystocele
2.3
14.7
116
532
UJF32
NOMESCO Finland
Coloscopy
1.8
14.7
279
1748
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
14.5
482
3506
N02AX02
ATC
tramadol; systemic, rectal
1.6
14.3
440
3135
M25.5
ICD-10 Finland
Pain in joint
1.6
14.2
435
3097
C51.11
ICD-10 Finland
Squamous cell carcinoma of the labium minus
43.0
14.1
17
*
R52.9
ICD-10 Finland
Pain, unspecified
2.1
14.1
141
711
U02
ICPC
Urinary frequency/urgency
1.8
14.0
244
1487
R51.80
ICD-10 Finland
Headache
1.8
13.8
242
1476
N06AX11
ATC
mirtazapine; oral
1.6
13.6
423
3014
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
13.6
250
1547
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
13.6
176
975
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.5
13.5
47
139
N95.0
ICD-10 Finland
Postmenopausal bleeding
2.1
13.5
138
702
M01AH05
ATC
etoricoxib; oral
1.6
13.4
713
5767
R06AX27
ATC
desloratadine; oral
1.6
13.4
413
2933
N76.4
ICD-10 Finland
Abscess of vulva
13.0
13.4
23
18
N30
ICD-10 Finland
Cystitis
2.0
13.4
155
825
C05AA08
ATC
fluocortolone; rectal, topical
2.0
13.4
153
811
A02BC03
ATC
lansoprazole; oral
1.7
13.3
311
2056
L43.8
ICD-10 Finland
Other lichen planus
4.2
13.3
35
85
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
13.1
133
674
H53.1
ICD-10 Finland
Subjective visual disturbances
2.3
12.9
102
467
J01FA10
ATC
azithromycin; systemic
1.6
12.7
744
6122
J01FF01
ATC
clindamycin; systemic
1.7
12.6
302
2007
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
12.5
318
2146
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
2.3
12.5
96
435
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.6
12.4
72
286
N81.6
ICD-10 Finland
Rectocele
2.2
12.4
113
550
N95.2
ICD-10 Finland
Postmenopausal atrophic vaginitis
2.1
12.4
132
682
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
2.8
12.3
60
218
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
12.2
80
337
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
2.4
12.2
86
375
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
12.1
495
3738
G04BD08
ATC
solifenacin; oral
2.5
12.1
79
333
D06BB10
ATC
imiquimod; topical
2.5
12.0
77
321
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
12.0
174
999
N06AX21
ATC
duloxetine; oral
1.9
11.9
169
962
Z71.8
ICD-10 Finland
Other specified counselling
1.6
11.9
472
3535
ZXE00
NOMESCO Finland
One hour or less
1.6
11.9
456
3390
S29
ICPC
Skin symptom/complaint other
1.7
11.9
266
1734
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.9
11.8
175
1011
G04BD12
ATC
mirabegron; oral
2.0
11.8
131
687
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
11.7
418
3053
K12.00
ICD-10 Finland
Recurrent oral aphthae
4.1
11.7
32
80
N03AX12
ATC
[U] gabapentin; oral
1.8
11.5
185
1095
N30.9
ICD-10 Finland
Cystitis, unspecified
2.2
11.5
106
517
A63.0
ICD-10 Finland
Anogenital (venereal) warts
2.6
11.5
65
255
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.5
11.5
28
64
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
+∞
11.5
11
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
11.5
694
5688
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.8
11.4
56
204
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
11.4
260
1702
R01AD09
ATC
mometasone; nasal
1.5
11.3
576
4540
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.0
11.2
122
634
K60.2
ICD-10 Finland
Anal fissure, unspecified
3.9
11.2
32
83
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
25.3
11.2
15
6
L29.9
ICD-10 Finland
Pruritus, unspecified
3.0
11.1
50
174
WX320
NOMESCO Finland
Spinalanesthesy
1.6
11.0
282
1898
E000006, ,
ATC
2.2
11.0
96
459
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
10.9
241
1560
J02AC02
ATC
itraconazole; systemic
1.7
10.9
203
1255
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.0
10.9
133
721
J01AA02
ATC
doxycycline; systemic
1.6
10.8
853
7363
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.1
10.8
109
552
M70.6
ICD-10 Finland
Trochanteric bursitis
1.8
10.7
188
1142
M35.2
ICD-10 Finland
Behçet disease
60.6
10.6
12
*
WX400
NOMESCO Finland
Inhalation anesthesy
2.5
10.6
65
266
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
4.0
10.5
29
73
S31.4
ICD-10 Finland
Open wound of vagina and vulva
14.4
10.5
17
12
M54.5
ICD-10 Finland
Low back pain
1.5
10.5
453
3433
N77.1*A60.0
ICD-10 Finland
Vaginitis, vulvitis and vulvovaginitis in herpesviral [herpes simplex] infection
12.2
10.4
18
15
Z2221
NOMESCO Finland
Medical doctor
1.6
10.3
330
2337
N90.4
ICD-10 Finland
Leukoplakia of vulva
10.7
10.3
19
18
N02BE01
ATC
paracetamol; systemic, rectal
1.9
10.2
1043
9531
R06.0
ICD-10 Finland
Dyspnoea
1.6
10.2
301
2094
R52.2
ICD-10 Finland
Other chronic pain
2.6
10.2
58
229
K30
ICD-10 Finland
Functional dyspepsia
1.8
10.1
157
919
N05CF01
ATC
zopiclone; oral
1.6
10.0
338
2422
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
9.9
146
840
UJH02
NOMESCO Finland
Anoscopy
2.7
9.9
53
203
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
9.8
377
2776
N02BF01
ATC
gabapentin; oral
1.9
9.8
133
745
JAH01
NOMESCO Finland
Laparoscopy
2.5
9.8
61
251
A02BC01
ATC
omeprazole; systemic
1.6
9.8
302
2117
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
9.8
461
3542
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
9.8
452
3461
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.8
9.7
173
1053
U01
ICPC
Dysuria/painful urination
1.9
9.7
138
785
C51.81
ICD-10 Finland
Squamous cell carcinoma of the vulva
55.5
9.7
11
*
B35.6
ICD-10 Finland
Tinea inguinalis [Tinea cruris]
5.3
9.7
19
36
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
9.6
355
2589
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
9.6
270
1851
R42
ICD-10 Finland
Dizziness and giddiness
1.6
9.6
264
1801
K13.78
ICD-10 Finland
Other change in the oral mucosa
3.2
9.5
38
123
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
9.5
288
2011
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
9.5
507
3990
N70.1
ICD-10 Finland
Chronic salpingitis and oophoritis
100.8
9.4
10
*
C51.9
ICD-10 Finland
Malignant neoplasm: Vulva, unspecified
17.7
9.4
14
8
LEE00
NOMESCO Finland
Suture of vagina
17.7
9.4
14
8
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.1
9.4
86
419
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
+∞
9.4
9
*
D20
ICPC
Mouth/tongue/lip symptom/complaint
2.3
9.4
73
333
G44.2
ICD-10 Finland
Tension-type headache
1.7
9.4
197
1256
N77.1
ICD-10 Finland
Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
4.6
9.3
22
49
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
9.3
223
1470
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.9
9.2
127
716
A07EA02
ATC
hydrocortisone; rectal
3.6
9.1
30
86
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
2.3
9.1
71
324
B00.9
ICD-10 Finland
Herpesviral infection, unspecified
7.1
9.0
21
30
M79.1
ICD-10 Finland
Myalgia
1.6
9.0
207
1350
M01AB05
ATC
diclofenac; systemic, rectal
1.5
9.0
702
5921
R30.0
ICD-10 Finland
Dysuria
2.4
9.0
61
262
TLC02
NOMESCO Finland
Simple extraction of IUD
2.3
8.9
68
307
D01
ICPC
Abdominal pain/cramps general
1.7
8.9
187
1190
B01AB05
ATC
enoxaparin; parenteral
1.5
8.9
326
2367
R02
ICPC
Shortness of breath/dyspnoea
1.7
8.9
162
992
R33
ICD-10 Finland
Retention of urine
2.7
8.9
46
173
LWW96
NOMESCO Finland
Other reoperation in gynaecological surgery
12.6
8.9
15
12
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.0
8.8
100
527
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
8.8
149
893
R01AD58
ATC
fluticasone, combinations; nasal
1.5
8.8
328
2390
EKA10
NOMESCO Finland
iopsy of buccal mucosa
3.3
8.8
33
103
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
8.8
163
1003
N75.0
ICD-10 Finland
Cyst of Bartholin gland
10.8
8.8
16
15
D06
ICPC
Abdominal pain localized other
1.8
8.8
132
764
J01MA12
ATC
levofloxacin; systemic
1.7
8.7
168
1046
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
8.6
261
1819
R05
ICD-10 Finland
Cough
1.6
8.5
265
1855
N39.3
ICD-10 Finland
Stress incontinence
1.9
8.5
112
622
L02
ICPC
Back symptom/complaint
1.7
8.5
149
904
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.5
8.4
51
208
M03BX02
ATC
tizanidine; oral
1.4
8.4
703
5972
H92.0
ICD-10 Finland
Otalgia
2.0
8.4
97
516
H02AB04
ATC
methylprednisolone; systemic
1.7
8.3
154
947
R03AC02
ATC
salbutamol; inhalant
1.4
8.3
661
5557
N89.0
ICD-10 Finland
Mild vaginal dysplasia
9.5
8.3
16
17
L43
ICD-10 Finland
Lichen planus
4.1
8.3
22
54
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
8.3
228
1552
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
8.3
215
1444
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
8.2
207
1378
P06
ICPC
Sleep disturbance
1.7
8.2
166
1045
XKC03
NOMESCO Finland
Water cystometry
2.9
8.2
38
135
J01FA06
ATC
roxithromycin; oral
1.4
8.1
437
3416
N75.1
ICD-10 Finland
Abscess of Bartholin gland
8.2
8.1
17
21
R07.3
ICD-10 Finland
Other chest pain
1.8
8.1
122
707
N75.8
ICD-10 Finland
Other diseases of Bartholin gland
17.3
8.1
12
7
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
17.3
8.1
12
7
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
8.0
259
1827
A01
ICPC
Pain general/multiple sites
1.8
8.0
132
786
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
7.3
8.0
18
25
L04
ICPC
Chest symptom/complaint
1.9
8.0
94
503
K59.0
ICD-10 Finland
Constipation
2.2
7.9
65
304
L01
ICPC
Neck symptom/complaint
1.6
7.9
224
1535
N06AB10
ATC
escitalopram; oral
1.5
7.9
271
1937
J01MA06
ATC
norfloxacin; oral
1.7
7.8
153
957
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
7.7
251
1770
U13
ICPC
Bladder symptom/complaint other
2.6
7.7
44
174
PJD55
NOMESCO Finland
Block dissection of inguinal lymph nodes
15.1
7.7
12
8
N05AH04
ATC
quetiapine; oral
1.6
7.7
208
1407
E000001, ,
ATC
1.5
7.7
243
1703
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
7.7
314
2322
XKD00
NOMESCO Finland
Uroflowmetry
2.4
7.7
51
217
R03BA05
ATC
fluticasone; inhalant
1.6
7.7
217
1484
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
7.6
128
765
WX402
NOMESCO Finland
General anaesthesia
1.5
7.6
253
1793
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.7
7.6
153
962
R01AD12
ATC
fluticasone furoate; nasal
1.4
7.6
401
3114
R53
ICD-10 Finland
Malaise and fatigue
1.5
7.6
311
2301
LEG12
NOMESCO Finland
Transobturatoric tape
3.5
7.6
25
72
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.1
7.5
71
351
SPAT1263
SPAT
Sampling
1.4
7.5
488
3933
L50.9
ICD-10 Finland
Urticaria, unspecified
2.3
7.5
56
252
U05
ICPC
Urination problems other
2.3
7.5
56
252
K60.0
ICD-10 Finland
Acute anal fissure
3.9
7.4
21
54
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
7.4
121
717
N70.9
ICD-10 Finland
Salpingitis and oophoritis, unspecified
80.6
7.4
8
*
F29
ICPC
Eye symptom/complaint other
1.7
7.4
138
850
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
13.5
7.4
12
9
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.3
7.4
53
234
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
7.4
196
1321
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
7.4
97
539
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
7.4
385
2982
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
7.3
870
7775
D07BC01
ATC
betamethasone and antiseptics; topical
1.8
7.3
121
720
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.2
7.3
63
300
R06AE07
ATC
cetirizine; oral
1.4
7.3
554
4581
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
7.2
165
1071
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
2.6
7.2
41
162
XKD03
NOMESCO Finland
Urethral pressure profilometry
3.1
7.2
30
100
X14
ICPC
Vaginal discharge
2.4
7.2
50
218
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.6
7.2
40
157
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
7.2
108
626
J01FA09
ATC
clarithromycin; systemic
1.4
7.1
356
2732
WX002
NOMESCO Finland
Sedation and analgesia
1.6
7.1
190
1282
C07AA05
ATC
propranolol; systemic
1.5
7.0
257
1856
R12
ICD-10 Finland
Heartburn
1.8
7.0
108
630
X29
ICPC
Genital sympt/compl female other
2.9
7.0
32
113
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.7
7.0
147
936
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
6.9
90
498
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
6.9
136
850
AA1AD
NOMESCO Finland
CT of head and brain
1.5
6.9
262
1905
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
2.4
6.9
46
197
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.1
6.9
63
308
A11
ICPC
Chest pain NOS
1.8
6.8
93
522
LDA10
NOMESCO Finland
Curettage of cervix uteri
2.1
6.8
65
323
L17
ICPC
Foot/toe symptom/complaint
1.4
6.8
360
2787
M79.7
ICD-10 Finland
Fibromyalgia
2.2
6.8
55
256
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
2.8
6.8
32
115
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
2.4
6.8
44
186
R14
ICD-10 Finland
Flatulence and related conditions
4.3
6.8
17
40
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
6.8
171
1138
LEF00
NOMESCO Finland
Anterior colporraphy with sutures for primary cystocele
2.2
6.8
54
250
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
6.7
91
510
N92.4
ICD-10 Finland
Excessive bleeding in the premenopausal period
2.2
6.7
55
257
X01
ICPC
Genital pain female
3.3
6.7
24
73
UJF92
NOMESCO Finland
Capsular endoscopy
3.0
6.7
28
94
K07.60
ICD-10 Finland
Snapping jaw
1.9
6.7
80
431
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.5
6.7
42
175
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
2.9
6.7
30
105
K05.1
ICD-10 Finland
Chronic gingivitis
1.9
6.7
89
497
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
3.1
6.6
27
89
R03AK07
ATC
formoterol and budesonide; inhalant
1.5
6.6
238
1710
G04CA02
ATC
tamsulosin; oral
2.8
6.6
31
111
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.9
6.6
29
100
U72
ICPC
Urethritis
2.4
6.6
42
176
LFA00
NOMESCO Finland
Incision of vulva or perineum
12.3
6.6
11
9
N76
ICD-10 Finland
Other inflammation of vagina and vulva
3.3
6.6
24
74
S21
ICPC
Skin texture symptom/complaint
1.6
6.6
183
1245
ZYC01
NOMESCO Finland
Remote contact by phone
1.9
6.6
76
405
R15
ICD-10 Finland
Faecal incontinence
2.4
6.5
44
189
R21
ICPC
Throat symptom/complaint
1.4
6.5
317
2413
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
6.5
169
1131
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
6.5
89
502
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
6.4
366
2865
C01CA24
ATC
epinephrine; parenteral
1.8
6.4
91
518
L04AX03
ATC
methotrexate; systemic
1.7
6.4
111
670
N05BA04
ATC
oxazepam; oral
1.4
6.4
296
2232
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
6.4
143
924
R96
ICPC
Asthma
1.7
6.3
121
750
WX702
NOMESCO Finland
Supraglottic ventilation device
2.0
6.3
66
339
R4110, ,
SPAT
1.6
6.3
153
1009
C09CA06
ATC
candesartan; oral
1.5
6.3
247
1806
N77.8*L43.9
ICD-10 Finland
Vulvovaginal ulceration and inflammation caused by lichen ruber planus
18.1
6.3
9
5
D07CC01
ATC
betamethasone and antibiotics; topical
1.6
6.3
141
912
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
6.3
479
3932
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
6.3
246
1798
61207
ICD-8 Finland
Acute salpingitis and oophoritis, suspecta
+∞
6.3
6
*
N77.8*M35.2
ICD-10 Finland
Ulceration of vulva in Behçet's disease
+∞
6.3
6
*
XX3DW
NOMESCO Finland
Time consuming IT work
1.7
6.2
104
621
LEE96
NOMESCO Finland
Other repair of vagina
26.8
6.2
8
*
F51.0
ICD-10 Finland
Nonorganic insomnia
1.5
6.2
227
1636
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
6.2
105
630
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
6.2
102
607
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
6.2
591
5021
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
6.3
6.2
15
24
N89.9
ICD-10 Finland
Noninflammatory disorder of vagina, unspecified
6.3
6.2
15
24
R74
ICPC
Upper respiratory infection acute
1.4
6.2
459
3750
XQ800
NOMESCO Finland
Prick test
1.7
6.1
103
616
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.8
6.1
30
110
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
1.9
6.1
82
458
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
6.1
845
7602
SDA03
NOMESCO Finland
Periodontal treatment
1.4
6.1
484
3990
K64.9
ICD-10 Finland
Haemorrhoids, unspecified
2.1
6.1
58
288
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
6.1
120
750
K60.1
ICD-10 Finland
Chronic anal fissure
2.7
6.1
32
122
N06AB04
ATC
citalopram; systemic
1.5
6.1
224
1617
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
6.0
72
388
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
6.0
139
905
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
102
133
8.31
74.50
1.3
1.1
—
—
—
0
0
524
2930
2.43
46.93
1.8
1.5
—
—
—
0
0
810
5933
2.19
32.85
5.1
3.9
0.00
0.01
estimate
1.23
181
1243
790
5831
2.10
29.98
5.0
3.8
0.00
0.00
estimate
0.50
184
1260
154
582
2.90
29.55
1.6
1.5
—
—
—
0
0
794
5897
2.08
29.27
5.0
3.8
0.03
7.14
estimate
1.82
188
1295
70
163
4.50
27.96
1.6
1.3
—
—
—
0
0
921
7332
2.21
26.93
7.1
4.6
1645.50
3601.43
e6/l
—
10
86
28
27
10.60
25.41
1.9
2.3
1.93
2.62
ug/l
0.35
23
13
462
3101
1.81
20.40
2.9
2.3
55.71
60.52
u/l
1.09
419
2827
283
1639
1.96
19.74
2.7
2.4
141.62
102.49
ug/g
0.86
235
1272
420
2767
1.81
19.53
4.1
3.0
0.21
0.41
e6/l
3.45
315
1958
678
5180
1.74
18.38
6.1
5.7
9.62
10.21
umol/l
1.45
644
4908
594
4379
1.73
18.29
4.7
3.7
0.03
0.06
estimate
0.48
147
1042
462
3179
1.75
18.20
4.2
3.1
33.41
56.72
e6/l
0.77
356
2346
928
7787
1.93
18.19
5.9
4.3
11.95
11.41
mm/h
0.53
874
7285
598
4427
1.72
18.05
6.4
5.5
1.22
1.22
mmol/l
0.16
560
4086
766
6106
1.74
17.33
10.2
9.0
3.91
3.94
e9/l
0.16
679
5350
588
4376
1.69
17.05
5.1
4.4
36.17
36.26
g/l
0.15
550
4099
460
3222
1.71
16.60
3.8
3.2
0.25
0.01
estimate
0.77
153
1037
915
7730
1.85
16.39
9.3
7.3
74.07
75.82
u/l
0.88
876
7302
221
1272
1.91
15.32
2.5
1.9
—
—
—
0
0
253
1522
1.85
15.28
3.8
2.8
5.22
4.71
e6/l
0.21
134
659
1120
10311
3.10
14.45
19.6
13.3
21.23
20.36
mg/l
0.38
959
8371
376
2586
1.67
14.00
1.6
1.5
2.22
2.16
g/l
0.29
226
1560
366
2504
1.67
13.89
4.5
3.7
94.84
93.97
%
0.30
352
2441
633
4963
1.60
13.73
6.8
6.2
1.22
1.22
mmol/l
0.10
534
4283
405
2862
1.64
13.45
2.4
2.1
121.94
145.87
u/l
1.21
382
2721
106
488
2.29
13.28
1.3
1.3
0.24
0.76
u/ml
—
5
31
247
1534
1.77
13.24
2.8
2.0
—
—
—
0
0
1107
10187
2.66
13.22
20.2
15.0
139.51
139.57
mmol/l
0.34
1093
9957
319
2132
1.68
13.11
2.9
2.3
—
—
—
0
0
324
2175
1.68
13.09
3.1
2.6
7.22
8.91
e6/l
1.24
290
1966
356
2451
1.65
13.03
2.0
1.8
0.93
1.03
mg/l
0.34
272
1867
458
3371
1.59
12.67
3.9
3.3
25.30
63.65
ng/l
0.97
264
2038
22
18
12.43
12.63
1.0
1.0
—
—
—
0
0
711
5800
1.58
12.47
5.3
4.3
6.33
6.40
mmol/l
0.45
659
5340
96
438
2.30
12.28
1.7
1.7
—
—
—
0
0
267
1733
1.70
12.12
3.8
3.6
69.23
366.22
ng/l
3.96
184
1171
152
832
1.95
12.09
1.5
1.3
808.84
208.37
u/ml
0.44
140
770
292
1943
1.67
12.06
2.8
2.1
—
—
—
0
0
1104
10202
2.50
12.05
20.6
15.1
3.90
3.91
mmol/l
0.76
1090
9946
261
1687
1.70
12.02
3.8
2.7
1.36
1.23
e6/l
0.11
144
826
437
3217
1.57
11.89
5.2
3.9
0.01
0.00
estimate
0.36
174
1218
191
1141
1.81
11.55
2.8
2.6
4.79
6.18
umol/l
1.98
163
981
130
686
2.01
11.47
1.7
1.6
—
—
—
0
0
239
1526
1.71
11.46
3.4
3.1
0.82
0.82
mmol/l
0.22
227
1440
26
57
4.64
11.22
2.3
1.6
—
—
—
0
0
418
3080
1.56
11.16
1.5
1.3
0.85
1.91
u/ml
2.08
109
806
820
7000
1.58
11.07
3.5
3.0
34.29
35.93
u/l
0.31
768
6625
458
3462
1.53
10.80
3.6
2.9
27.73
28.27
u/l
0.16
430
3276
179
1069
1.80
10.80
2.3
2.1
373.02
385.92
nmol/l
0.37
166
984
1000
8993
1.78
10.74
5.9
4.9
14.63
14.63
pmol/l
0.02
943
8326
566
4491
1.51
10.52
2.4
2.0
101.42
97.76
pmol/l
0.90
306
2275
24
54
4.52
10.05
1.4
3.1
101.61
103.13
%
0.06
18
54
510
3996
1.49
9.87
15.2
11.8
1.19
1.17
inr
0.26
439
3308
19
37
5.20
9.38
1.1
1.2
94.00
94.29
%
—
7
21
1132
10722
2.81
9.21
14.7
10.9
22.98
22.93
u/l
0.04
1106
10418
320
2304
1.54
9.15
1.4
1.3
21.01
28.64
iu/ml
1.13
98
698
302
2154
1.54
8.99
1.5
1.3
12.34
11.95
u/ml
0.03
113
840
97
506
2.00
8.83
2.2
1.9
10.24
6.74
iu/ml
0.38
21
111
232
1566
1.60
8.76
1.8
1.7
1212.74
1190.28
nmol/l
0.13
187
1169
238
1619
1.59
8.69
2.5
2.4
13.42
13.38
umol/l
0.02
219
1499
625
5183
1.44
8.57
3.3
2.7
—
—
estimate
—
0
0
712
6055
1.45
8.49
4.0
3.2
72.11
74.13
ug/l
0.23
679
5683
123
704
1.84
8.48
1.3
1.3
17.00
43.11
au/ml
—
7
41
1131
10752
2.64
8.30
23.3
16.8
67.93
68.12
umol/l
0.11
1122
10618
220
1484
1.59
8.29
2.5
2.3
2.40
2.41
g/l
0.10
199
1367
132
779
1.78
8.23
2.5
2.4
35.97
20.84
au/ml
0.76
20
81
628
5241
1.43
8.15
2.9
2.5
80.52
77.37
nmol/l
2.07
594
4809
75
367
2.12
8.12
1.4
1.3
—
—
—
0
0
18
39
4.67
7.89
1.1
1.1
97.33
92.18
%
—
6
22
367
2796
1.46
7.73
2.1
1.7
—
—
—
0
0
22
57
3.91
7.72
1.0
1.1
—
—
—
0
0
62
289
2.21
7.60
1.7
1.6
—
—
—
0
0
134
813
1.73
7.59
1.4
1.4
25.59
23.41
iu/l
0.29
114
704
1047
9731
1.73
7.58
17.8
12.8
86.35
85.82
ml/min/173m2
0.34
973
8841
200
1346
1.59
7.57
2.7
2.4
22.81
22.24
%
0.18
183
1251
200
1346
1.59
7.57
2.6
2.1
30.75
29.01
s
2.55
190
1300
338
2544
1.46
7.56
4.7
4.0
1.02
1.62
kg/l
0.50
239
1660
218
1503
1.55
7.42
2.0
1.8
—
—
—
0
0
1075
10078
1.84
7.41
7.4
6.0
1.77
1.83
mu/l
1.11
1033
9485
57
262
2.24
7.23
1.0
1.4
3.78
3.72
mmol/l
0.12
52
251
62
296
2.16
7.17
1.4
1.4
299.86
304.08
ug/g
0.05
31
162
159
1030
1.63
7.03
2.5
2.3
29.85
37.82
u/l
2.05
134
845
66
328
2.07
6.90
2.4
2.9
178.83
176.08
%
0.08
59
315
54
251
2.21
6.69
1.1
1.6
49.45
19.19
e6/l
0.51
31
184
976
8979
1.53
6.65
23.9
16.8
13.51
13.48
%
0.27
969
8845
129
803
1.68
6.65
3.6
3.1
10.89
10.50
g/l
0.54
119
735
50
226
2.27
6.62
1.9
1.5
—
—
—
0
0
373
2921
1.41
6.55
2.5
2.2
2.71
2.70
mg/l
0.03
335
2503
54
254
2.18
6.51
1.1
1.6
914.20
218.53
e6/l
0.41
35
199
462
3754
1.38
6.50
3.4
3.3
2.35
2.36
mmol/l
1.85
429
3443
130
816
1.67
6.50
2.8
3.4
24.50
71.68
u/ml
2.21
119
788
63
320
2.02
6.23
1.2
1.2
3.56
4.69
—
5
39
368
2897
1.39
6.20
1.7
1.6
21.85
21.30
nmol/l
0.28
324
2471
23
74
3.15
5.91
2.7
1.8
—
—
—
0
0
147
974
1.58
5.91
3.6
4.4
251.87
244.66
u/l
0.11
136
915
166
1133
1.54
5.86
1.9
1.7
—
—
—
0
0
100
605
1.71
5.74
2.9
2.8
110.72
190.95
ng/l
2.83
88
552
20
60
3.37
5.74
1.4
1.1
—
—
—
0
0
143
948
1.58
5.73
3.4
3.1
—
—
—
0
0
112
699
1.67
5.73
1.5
1.4
—
—
—
0
0
15
27
5.61
5.69
1.1
1.6
90.07
100.89
%
0.61
15
27
114
720
1.65
5.57
2.3
2.8
67.49
66.89
g/l
0.43
106
668
834
7533
1.37
5.57
4.1
3.5
—
—
—
0
0
396
3204
1.36
5.50
3.1
3.2
6.48
6.81
mmol/l
0.78
336
2747
1156
11252
3.66
5.46
30.1
21.0
263.49
264.32
e9/l
0.17
1148
11044
1156
11257
3.62
5.35
30.0
21.0
4.40
4.41
e12/l
0.30
1145
11012
1156
11258
3.61
5.33
30.1
21.0
6.65
6.68
e9/l
0.20
1145
11014
102
637
1.66
5.22
1.7
1.6
381.34
303.45
mu/l
0.90
89
564
168
1180
1.49
5.17
1.6
1.6
1.39
1.36
%
0.32
145
1042
158
1096
1.51
5.16
1.8
1.8
—
—
—
0
0
1028
9681
1.52
5.06
5.2
4.6
5.73
5.71
mmol/l
0.16
965
8950
38
175
2.21
4.88
4.5
4.6
140.00
348.41
iu/ml
—
6
17
39
182
2.18
4.86
1.4
1.4
136.80
155.54
au/ml
—
10
57
20
67
3.02
4.84
1.5
1.6
7.95
7.61
ug/l
0.03
15
60
268
2086
1.37
4.66
1.7
1.7
27602267.68
27247154.82
pmol/l
0.00
221
1747
310
2473
1.35
4.59
3.5
3.0
971.29
961.68
ng/l
0.02
258
2067
271
2119
1.36
4.57
3.1
2.6
2.45
2.45
mmol/l
0.18
242
1904
984
9227
1.42
4.57
6.4
5.5
38.05
37.97
mmol/mol
0.11
934
8675
121
814
1.54
4.56
3.7
3.3
1.23
1.23
mmol/l
0.01
104
690
15
36
4.21
4.52
5.3
3.4
143.00
131.67
umol/l
—
8
24
42
208
2.06
4.52
1.4
1.4
241.85
238.63
u/ml
0.03
32
123
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
17
55
3.12
4.37
1.0
1.2
—
—
—
0
0
59
333
1.81
4.35
1.2
1.1
2.46
3.25
u/ml
0.18
33
179
30
133
2.29
4.25
1.5
1.9
1.57
1.67
mmol/l
0.32
30
133
25
102
2.48
4.23
1.2
1.3
0.24
3.37
u/ml
1.19
14
55
130
907
1.49
4.14
7.9
6.6
0.83
0.93
mmol/l
0.12
104
755
56
316
1.81
4.14
2.2
3.0
3.37
3.55
g/l
0.43
50
304
69
414
1.71
4.14
1.3
1.3
—
—
—
0
0
38
189
2.04
4.07
1.4
1.3
6.06
4.58
u/ml
0.13
17
84
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
43
224
1.95
4.05
5.5
3.7
0.49
0.40
iu/ml
0.70
19
128
345
2840
1.30
4.03
4.0
4.0
6.91
7.47
mg/mmol
0.11
190
1656
62
365
1.74
3.99
1.1
1.3
12.77
11.16
u/l
0.28
49
294
62
367
1.73
3.92
1.5
1.5
0.05
0.29
iu/ml
0.65
14
55
14
43
3.28
3.91
1.7
1.8
79.00
84.21
nmol/24h
0.13
14
43
52
293
1.81
3.88
1.1
1.1
11.86
4.07
u/ml
1.24
26
162
123
865
1.47
3.78
3.3
3.5
4.42
4.55
pmol/l
0.90
115
780
40
209
1.95
3.76
1.3
1.3
—
—
—
0
0
90
594
1.56
3.73
2.2
2.3
6.14
6.65
ug/l
0.14
74
521
287
2326
1.31
3.72
2.4
2.4
309.08
308.01
umol/l
0.07
257
2059
127
902
1.46
3.71
2.3
2.3
0.22
0.21
g/l
0.13
118
845
14
40
3.53
3.61
1.1
2.4
—
—
—
0
0
26
118
2.23
3.53
1.4
1.8
18.43
22.64
ng/l
0.81
26
118
103
709
1.50
3.53
2.5
2.3
0.30
0.58
e6/l
0.95
95
672
20
81
2.49
3.47
1.1
1.3
33.48
25.62
umol/l
0.42
20
74
15
52
2.91
3.47
1.1
1.1
—
—
—
0
0
148
1096
1.40
3.45
1.3
1.2
185.37
148.74
u/ml
0.38
55
428
314
2600
1.28
3.43
2.7
2.1
—
—
—
0
0
49
283
1.76
3.40
1.1
1.1
0.76
0.68
u/ml
0.10
26
122
60
369
1.66
3.34
1.6
2.1
1.45
1.46
g/l
0.03
49
320
115
819
1.45
3.33
2.9
3.6
76.25
77.69
ng/l
0.07
102
713
21
89
2.38
3.33
8.5
6.5
12.59
12.48
mg/l
0.04
21
83
48
278
1.76
3.31
1.1
1.1
0.62
1.89
u/ml
2.31
22
140
25
117
2.16
3.18
5.1
3.2
1.77
1.19
%
0.26
20
108
35
186
1.91
3.17
1.1
1.1
—
—
—
0
0
42
237
1.80
3.17
2.9
3.9
1.02
2.46
ratio
2.49
16
124
32
165
1.97
3.16
1.3
1.3
—
—
—
0
0
126
924
1.41
3.12
2.3
2.2
2022.98
7532.81
u/l
3.99
41
388
34
181
1.90
3.07
1.2
1.4
—
—
—
0
0
34
181
1.90
3.07
1.2
1.4
—
—
—
0
0
28
139
2.04
3.07
1.1
1.1
91.61
94.40
%
0.19
28
128
8
16
5.03
3.05
1.3
1.1
—
—
—
0
0
35
190
1.87
2.99
1.4
1.2
7.64
3.21
u/ml
0.29
11
68
74
493
1.53
2.98
1.4
1.5
—
—
—
0
0
40
227
1.79
2.98
1.1
1.1
10.67
6.32
u/ml
0.32
16
102
154
1177
1.36
2.97
5.3
4.9
1.06
1.05
mmol/l
0.16
143
1073
15
57
2.65
2.97
1.3
1.1
—
—
—
0
0
51
311
1.67
2.96
1.8
1.2
—
—
—
0
0
27
136
2.01
2.87
1.2
1.4
—
—
—
0
0
43
256
1.71
2.74
1.6
1.3
—
—
—
0
0
47
287
1.66
2.73
1.4
1.3
6.30
5.90
u/ml
—
5
19
51
319
1.63
2.71
2.5
2.6
0.37
0.80
g/l
0.89
44
278
57
367
1.58
2.69
1.5
1.3
17.14
2.56
u/ml
—
8
37
45
273
1.67
2.68
2.9
3.8
30.04
41.87
mg/l
1.27
33
234
45
274
1.67
2.65
2.9
3.8
46.88
53.45
mg/l
0.12
33
234
22
106
2.10
2.64
1.4
1.1
—
—
—
0
0
66
442
1.52
2.63
1.9
1.6
6.41
11.15
u/ml
0.93
19
98
17
74
2.32
2.58
1.2
1.3
—
—
—
0
0
5
7
7.17
2.55
2.8
1.1
—
—
—
0
0
17
75
2.29
2.51
1.2
1.3
—
—
—
0
0
7
16
4.39
2.47
1.0
1.1
—
—
—
0
0
22
109
2.04
2.47
1.4
1.1
—
—
—
0
0
36
211
1.73
2.45
1.2
1.3
—
—
—
0
0
21
103
2.06
2.42
1.4
1.1
—
—
—
0
0
48
306
1.59
2.39
1.4
1.3
32.80
49.34
u/ml
—
8
34
103
766
1.38
2.39
2.3
2.5
70.33
69.82
ml/min/173m2
0.04
46
304
5
8
6.27
2.37
1.4
1.6
—
—
—
0
0
472
4224
1.20
2.35
2.1
1.9
1.26
1.29
mmol/l
0.26
400
3637
46
292
1.60
2.34
1.2
1.5
0.42
0.40
nmol/l
0.10
35
239
32
184
1.76
2.33
1.3
1.3
—
—
—
0
0
63
431
1.49
2.30
1.7
2.2
43.25
40.93
u/l
0.40
57
391
40
247
1.64
2.27
1.1
1.0
3.35
5.39
u/ml
0.61
17
126
24
127
1.91
2.27
1.3
1.2
0.16
0.33
nmol/l
0.54
19
90
55
368
1.52
2.24
1.5
1.3
14.34
7.23
u/ml
—
10
59
18
86
2.11
2.23
3.3
3.0
12.75
13.62
index
—
8
47
50
328
1.55
2.22
1.2
1.1
—
—
—
0
0
21
107
1.98
2.21
1.4
1.1
—
—
—
0
0
23
122
1.90
2.17
1.3
1.5
—
—
—
0
0
21
108
1.96
2.16
1.4
1.1
—
—
—
0
0
6
14
4.30
2.15
1.2
1.5
—
—
—
0
0
11
42
2.63
2.14
1.0
1.2
—
—
—
0
0
112
861
1.33
2.12
4.2
3.7
2.19
1.88
mmol/l
0.36
102
750
15
68
2.22
2.11
1.0
2.0
—
2.37
—
0
23
60
416
1.47
2.08
1.5
1.5
0.22
0.29
mg/l
0.46
29
165
1025
9908
1.28
2.08
5.1
4.6
4.63
4.76
mmol/l
4.34
977
9310
22
118
1.88
2.02
4.9
4.5
36.73
46.63
u/ml
—
7
35
37
232
1.61
2.01
1.1
1.1
54.08
12.58
au/ml
—
8
54
13
57
2.30
1.98
1.3
1.4
—
—
—
0
0
1019
9854
1.27
1.98
4.9
4.5
1.53
1.57
mmol/l
2.67
964
9214
33
202
1.65
1.97
1.1
1.1
—
—
—
0
0
34
210
1.64
1.96
1.1
1.1
0.05
0.08
u/ml
—
8
64
48
323
1.51
1.94
1.1
1.1
—
—
—
0
0
37
235
1.59
1.92
1.5
1.4
—
—
—
0
0
23
128
1.81
1.90
1.3
1.1
—
—
—
0
0
45
300
1.52
1.90
1.7
2.3
5.43
5.00
umol/l
0.13
32
221
73
535
1.39
1.89
1.8
1.7
—
—
—
0
0
0
50
0.00
1.89
0.0
2.4
—
54.87
—
0
43
8
28
2.87
1.86
2.3
1.5
10.92
8.29
ug/l
—
8
28
114
898
1.30
1.84
3.0
4.1
10.42
10.43
ug/l
0.00
87
708
1034
10035
1.26
1.81
5.9
5.2
2.67
2.77
mmol/l
3.38
981
9407
12
53
2.28
1.81
1.3
1.4
—
—
—
0
0
74
551
1.37
1.76
5.1
3.9
24.78
24.20
mmol/l
0.82
74
542
12
54
2.23
1.74
3.2
2.9
442.17
1013.46
u/ml
1.38
12
54
40
269
1.50
1.65
3.2
3.0
1.13
2.01
index
0.62
16
127
92
717
1.31
1.63
1.4
1.4
—
—
—
0
0
23
135
1.72
1.63
1.3
1.3
—
28.80
—
0
5
7
26
2.70
1.58
2.6
2.8
0.60
0.62
mmol/l
—
7
26
34
224
1.53
1.55
1.5
1.7
4057.95
14866.67
e6/l
2.07
20
147
25
153
1.65
1.54
1.6
1.5
—
—
—
0
0
94
742
1.29
1.53
1.0
1.1
—
—
—
0
0
30
193
1.57
1.52
2.0
1.9
—
—
—
0
0
37
250
1.50
1.51
1.6
1.4
—
—
—
0
0
7
27
2.60
1.51
1.6
2.1
1.25
1.91
ratio
—
7
27
28
178
1.59
1.49
1.6
1.5
—
—
—
0
0
20
116
1.74
1.49
1.1
1.1
—
—
—
0
0
9
38
2.38
1.45
1.7
1.2
—
—
—
0
0
9
38
2.38
1.45
1.1
1.4
—
—
—
0
0
960
9293
1.19
1.44
4.2
3.8
1.21
1.19
mmol/l
0.50
893
8608
13
66
1.98
1.43
6.5
6.3
14.93
22.55
ug/l
—
6
39
9
39
2.32
1.43
1.7
1.2
—
—
—
0
0
12
60
2.01
1.38
1.3
1.3
—
—
—
0
0
14
75
1.88
1.34
1.2
1.5
—
—
—
0
0
34
233
1.47
1.33
1.4
1.4
—
—
—
0
0
6
24
2.51
1.30
2.0
1.1
—
—
—
0
0
6
24
2.51
1.30
2.0
1.1
—
—
—
0
0
9
44
2.05
1.27
1.1
1.4
—
—
—
0
0
17
100
1.71
1.24
1.1
1.1
8.17
12.28
u/ml
—
9
49
13
71
1.84
1.19
1.3
1.4
—
—
—
0
0
19
117
1.63
1.18
1.2
1.5
—
—
—
0
0
55
421
1.32
1.17
3.7
3.4
2.13
1.74
mmol/l
0.41
42
305
18
110
1.65
1.15
1.3
2.0
28.56
31.47
pg
1.35
18
110
23
150
1.54
1.15
1.5
1.3
—
—
—
0
0
40
292
1.38
1.15
2.1
1.8
—
—
—
0
0
31
216
1.45
1.14
2.9
2.0
125.80
127.57
g/l
0.16
25
182
7
30
2.34
1.12
3.1
4.0
—
—
—
0
0
30
211
1.43
1.07
1.6
1.9
3.78
4.80
mmol/24h
1.29
25
186
73
594
1.24
1.00
1.4
1.3
205.96
245.12
miu/ml
0.48
38
292
13
76
1.72
0.99
1.2
1.1
—
—
—
0
0
12
69
1.75
0.96
1.1
1.4
—
—
—
0
0
23
157
1.47
0.96
1.1
1.2
—
296.67
—
0
12
18
117
1.55
0.94
1.4
1.6
—
—
—
0
0
53
419
1.28
0.93
1.8
2.3
3.52
16.38
iu/l
0.52
22
186
6
30
2.01
0.87
1.2
1.1
—
—
—
0
0
23
161
1.44
0.87
3.2
2.4
42.75
102.56
ug/min
0.54
15
102
8
44
1.82
0.86
1.0
1.3
—
—
—
0
0
6
31
1.94
0.84
1.0
1.2
—
—
—
0
0
8
46
1.74
0.82
1.0
1.2
104.50
190.55
iu/ml
—
8
46
17
113
1.51
0.82
1.1
1.1
—
—
—
0
0
13
81
1.61
0.81
1.4
1.3
0.86
0.62
ratio
—
6
43
0
24
0.00
0.79
0.0
1.1
—
1.25
—
0
24
12
74
1.63
0.78
1.8
1.4
—
—
—
0
0
11
67
1.65
0.75
1.6
1.3
66.09
71.93
umol/l
0.62
11
67
12
75
1.61
0.75
3.3
3.5
—
—
—
0
0
9
56
1.61
0.72
1.1
1.1
6.78
7.73
mm/h
—
9
56
13
84
1.55
0.72
1.6
1.5
0.52
0.48
e9/l
0.22
13
84
17
117
1.46
0.72
1.1
1.1
1.50
1.48
g/l
0.11
17
107
7
40
1.75
0.71
1.1
1.2
—
—
—
0
0
5
26
1.93
0.70
1.6
1.1
7.18
6.47
nmol/l
—
5
26
5
26
1.93
0.70
3.0
2.2
18.22
15.66
umol/l
—
5
26
15
102
1.48
0.67
1.2
1.1
—
—
—
0
0
10
62
1.62
0.65
1.0
1.0
769.20
787.86
ng/l
—
10
44
12
79
1.52
0.62
1.3
1.4
—
—
—
0
0
10
63
1.59
0.62
1.0
1.1
1375.16
1456.08
miu/ml
—
10
63
13
88
1.48
0.60
1.8
1.4
—
—
—
0
0
40
326
1.24
0.60
2.3
1.8
—
—
—
0
0
28
219
1.29
0.59
2.8
2.7
—
—
—
0
0
50
420
1.20
0.57
3.0
3.4
47.92
45.81
%
0.26
50
413
116
1041
1.13
0.57
6.9
5.8
—
—
—
0
0
12
81
1.49
0.57
1.1
1.1
—
—
—
0
0
16
115
1.40
0.56
2.7
1.2
—
—
—
0
0
16
115
1.40
0.56
2.8
1.2
—
—
—
0
0
16
115
1.40
0.56
2.8
1.2
—
—
—
0
0
8
55
1.46
0.56
1.4
1.2
13.62
20.40
u/l
—
8
50
26
203
1.29
0.56
1.8
1.6
—
—
—
0
0
13
90
1.45
0.55
1.2
1.1
—
—
—
0
0
11
74
1.49
0.53
1.1
1.2
—
186.88
—
0
16
35
286
1.23
0.53
1.5
1.2
—
—
—
0
0
7
45
1.56
0.49
1.0
1.1
42.06
60.46
u/ml
—
7
45
15
110
1.37
0.49
1.3
1.9
—
—
—
0
0
13
177
0.73
0.47
1.5
1.7
7.25
7.65
mmol/l
0.34
13
168
15
112
1.34
0.44
2.8
1.2
—
—
—
0
0
15
112
1.34
0.44
2.8
1.2
—
—
—
0
0
63
555
1.14
0.44
3.9
3.3
1.02
1.02
ratio
0.79
55
501
11
78
1.41
0.43
1.4
1.0
—
—
—
0
0
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
36
424
0.84
0.42
1.1
1.1
1.55
1.60
g/l
0.72
36
424
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
8
58
1.38
0.41
1.0
1.3
—
—
—
0
0
5
33
1.52
0.41
1.0
1.3
—
—
—
0
0
5
34
1.47
0.40
4.0
2.9
21.66
28.65
umol/l
—
5
26
5
35
1.43
0.39
1.4
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
42
363
1.16
0.39
2.3
2.9
25.11
25.48
mmol/l
0.32
42
352
79
872
0.90
0.38
1.4
1.4
—
—
—
0
0
57
505
1.14
0.38
2.3
1.6
6.56
4.63
mg/l
0.40
43
364
34
397
0.85
0.37
1.0
1.1
0.61
0.62
ratio
—
7
44
6
45
1.34
0.33
8.0
1.9
208.50
183.67
u/l
—
6
45
26
219
1.19
0.33
1.7
1.4
24.67
19.49
u/l
0.38
21
191
7
53
1.32
0.31
1.4
1.4
15.90
13.96
pmol/l
—
7
42
16
196
0.81
0.30
4.7
3.2
22.27
24.11
mg/l
—
10
124
14
111
1.26
0.30
2.9
1.2
—
—
—
0
0
21
176
1.20
0.29
1.1
1.1
2.36
2.84
eliau/ml
—
9
83
130
1379
0.94
0.28
1.5
1.6
1083.29
997.90
mu/l
0.44
109
1187
13
103
1.27
0.28
1.4
1.1
99.08
110.43
pmol/l
0.38
13
103
39
437
0.89
0.27
1.1
1.2
0.86
0.86
g/l
0.03
39
437
106
1130
0.93
0.27
5.0
4.4
33.80
33.60
%
0.07
74
769
19
159
1.20
0.27
1.6
1.3
—
—
—
0
0
13
104
1.25
0.26
2.8
2.1
25.80
18.67
mg/l
—
5
39
9
72
1.25
0.25
2.8
2.1
—
—
—
0
0
9
73
1.23
0.25
1.0
1.0
285.33
309.59
mg/l
—
9
63
9
77
1.17
0.24
16.8
13.2
0.67
0.61
mmol/l
—
9
72
5
38
1.32
0.23
1.4
1.0
—
—
—
0
0
5
39
1.28
0.23
3.0
1.3
—
—
—
0
0
5
39
1.28
0.23
3.0
1.3
—
—
—
0
0
5
39
1.28
0.23
3.0
1.3
—
—
—
0
0
5
39
1.28
0.23
3.0
1.3
—
—
—
0
0
5
42
1.19
0.21
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
6.9
—
9.97
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
50
537
0.93
0.17
1.4
1.5
67.80
59.89
ug/l
0.48
50
537
10
117
0.85
0.13
1.1
1.2
—
1317.45
—
0
13
63
600
1.05
0.12
1.8
1.8
—
—
—
0
0
13
114
1.14
0.12
1.1
1.2
—
—
—
0
0
73
700
1.05
0.11
1.5
1.5
—
—
—
0
0
60
573
1.05
0.11
1.5
1.4
—
—
—
0
0
19
174
1.09
0.09
1.5
1.6
—
—
—
0
0
97
943
1.03
0.08
1.5
1.6
3.20
3.37
mmol/l
0.92
64
633
7
66
1.06
0.08
2.4
1.3
—
—
—
0
0
7
66
1.06
0.08
2.4
1.3
—
—
—
0
0
7
66
1.06
0.08
2.4
1.3
—
—
—
0
0
73
709
1.03
0.07
1.6
1.5
1.27
1.13
ratio
0.47
40
435
8
90
0.89
0.06
1.4
1.4
—
—
—
0
0
73
710
1.03
0.06
1.6
1.5
1.20
1.18
ratio
0.07
41
438
73
710
1.03
0.06
1.6
1.5
0.96
0.95
ratio
0.05
40
436
63
647
0.97
0.05
1.5
1.7
—
—
—
0
0
37
381
0.97
0.03
1.3
1.3
—
—
—
0
0
13
124
1.05
0.00
4.1
2.3
5.09
38.75
u/ml
0.58
13
124
14
136
1.03
0.00
4.9
4.2
17.28
80.31
u/ml
1.91
14
136
17
169
1.01
0.00
3.6
3.8
0.67
0.78
nmol/l
—
9
142
77
769
1.00
0.00
1.6
1.5
66.26
59.12
ug/l
0.61
63
661
124
1241
1.00
0.00
1.8
1.8
3.09
3.23
ratio
0.81
90
923
0
6
0.00
0.00
0.0
1.2
—
7.75
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
7.76
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
20.28
—
0
5
5
50
1.00
0.00
1.4
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
34.54
—
0
5
5
50
1.00
0.00
1.4
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
11.00
—
0
6
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
93
0.97
-0.00
1.1
1.1
6.13
6.45
umol/l
—
9
86
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
7.29
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint N14_ULCERVAGVUL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_ULCERVAGVUL | 1.353 [1.16, 1.58] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.025 |
During the follow-up period (1.1.1998 — 31.12.2019), 484 out of 4215 females with N14_ULCERVAGVUL died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_ULCERVAGVUL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.134% | No data |
| 5 | 0.701% | No data |
| 10 | 1.616% | No data |
| 15 | 3.088% | No data |
| 20 | 5.684% | No data |
Relationships between endpoints
↥Index endpoint: N14_ULCERVAGVUL – Ulcer of vagina/vulva
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data