No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
209 |
4. Check minimum number of eventsNone |
209 |
5. Include endpointsNone |
209 |
6. Filter based on genotype QC (FinnGen only) |
193 |
Control definitions (FinnGen only)
- Control exclude
- Q17_OTHER_CONGEN_MALFO
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Marfan's syndrome
based on the number of shared cases.
Similar with more cases:
- Other specified congenital malformation syndromes affecting multiple systems
- Exclusion endpoint for clefts
- Clefts and syndromes for tooth agenesis exclusion, including avohilmo
- Other congenital malformations
- Other congenital malformations, including avohilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 193 | 94 | 99 |
| Unadjusted period prevalence (%) | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | 35.77 | 33.64 | 37.80 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 198
- Matched controls
- 1980
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q87.4
ICD-10 Finland
Marfan syndrome
+∞
286.6
198
*
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
88.6
169.6
94
20
Z31.5
ICD-10 Finland
Genetic counselling
36.8
144.5
110
65
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
15.5
88.4
119
175
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
24.8
72.6
56
31
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
20.7
59.3
49
31
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
9.3
56.8
112
243
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
13.2
54.1
60
63
B01AA03
ATC
warfarin; systemic
10.2
53.4
78
119
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
11.2
47.6
59
72
I34.1
ICD-10 Finland
Mitral (valve) prolapse
19.2
46.4
39
25
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
96.2
42.0
45
6
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
492.6
41.8
40
*
PD5BD
NOMESCO Finland
Extensive CT of aorta
51.2
34.7
41
10
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
60.2
34.0
39
8
WX872
NOMESCO Finland
Intensive care
11.2
32.9
38
41
XF400
NOMESCO Finland
ECG with 12 standard connections
6.4
29.8
62
132
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
339.0
29.6
29
*
I71.09
ICD-10 Finland
Aortic dissection [regardless of location]
168.8
28.5
29
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
10.1
27.5
34
40
XF404
NOMESCO Finland
Ambulatory ECG
7.7
27.5
44
71
H27.1
ICD-10 Finland
Dislocation of lens
297.5
26.4
26
*
TFP20
NOMESCO Finland
Cardiodefibrillation
8.8
25.9
36
49
C07AB07
ATC
bisoprolol; oral
4.8
25.9
126
531
I71.00
ICD-10 Finland
Dissecting aneurysm of aorta (ruptured) [any part]
148.8
25.2
26
*
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
11.1
24.7
28
29
I71.01
ICD-10 Finland
Aneurysm of the descending aorta
271.5
24.2
24
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.3
22.8
90
319
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.9
22.0
33
49
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.9
21.5
60
162
I48
ICD-10 Finland
Atrial fibrillation and flutter
5.1
20.4
51
125
PD5AD
NOMESCO Finland
CT of aorta
23.0
19.7
28
14
C09CA01
ATC
losartan; oral
4.1
19.4
76
263
ZXE20
NOMESCO Finland
More than three and less than five hours
4.9
19.1
50
127
7598B
ICD-9 Finland
Other and unspecified congenital anomalies, Other specified anomalies[SYNDROMA MARFAN]
+∞
19.1
18
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
5.8
18.7
39
81
Z2221
NOMESCO Finland
Medical doctor
3.7
18.0
91
371
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
32.3
17.9
23
8
TPH07
NOMESCO Finland
Cathetrisation of artery
5.2
17.6
41
94
PD5BG
NOMESCO Finland
MRI examination of thoracal and abdominal aortta with high intensity magnet
+∞
16.9
16
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.1
16.9
59
186
C01AA05
ATC
digoxin; systemic
15.4
16.6
27
20
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
33.3
16.5
21
7
XF640, ,
NOMESCO Finland
17.7
16.2
25
16
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
+∞
15.8
15
*
K78
ICPC
Atrial fibrillation/flutter
7.2
15.8
25
39
ZXD10
NOMESCO Finland
Scheduled procedure
3.2
14.5
96
450
H52.1
ICD-10 Finland
Myopia
6.2
14.2
26
47
B01AB05
ATC
enoxaparin; parenteral
3.3
14.2
81
347
R4110
NOMESCO Finland
Physiotherapy
3.3
14.1
79
335
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
57.7
14.0
16
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
6.5
13.9
24
41
I71.1
ICD-10 Finland
Thoracic aortic aneurysm, ruptured
80.9
13.8
15
*
WX892
NOMESCO Finland
Monitored bed care
5.3
13.6
30
65
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
6.6
12.9
22
37
PD5CM
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
12.6
12
*
FCC50
NOMESCO Finland
Resection and reconstruction of descending aorta using tube graft
+∞
12.6
12
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
15.7
12.6
20
14
C07AB03
ATC
atenolol; systemic
10.0
12.2
24
27
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
12.0
110
601
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
32.2
11.8
15
5
K83
ICPC
Heart valve disease NOS
24.7
11.8
16
7
I50.9
ICD-10 Finland
Heart failure, unspecified
4.9
11.7
28
65
FCD60
NOMESCO Finland
Resection of thoracoabdominal aorta and reimplantation of branches
+∞
11.6
11
*
FCA75
NOMESCO Finland
Valve-sparing repair of aortic root (David, Yacoub)
127.1
11.6
12
*
C07AA07
ATC
sotalol; systemic
15.1
11.2
18
13
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
19.2
10.9
16
9
K84
ICPC
Heart disease other
14.0
10.9
18
14
K99
ICPC
Cardiovascular disease other
23.0
10.9
15
7
26
HP
Aortic root """"composite graft""""
+∞
10.5
10
*
PDG51
NOMESCO Finland
Bypass from aorta to iliac artery for aneurysm
+∞
10.5
10
*
75980
ICD-8 Finland
Congenital syndromes affecting multiple systems, Syndroma Marfan, arachnodactylia
+∞
10.5
10
*
Z82.6
ICD-10 Finland
Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
+∞
10.5
10
*
I71.6
ICD-10 Finland
Thoracoabdominal aortic aneurysm, without mention of rupture
+∞
10.5
10
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
4.1
10.5
31
85
WX402
NOMESCO Finland
General anaesthesia
2.9
10.3
65
287
ZXE00
NOMESCO Finland
One hour or less
2.7
10.3
96
518
ZXE10
NOMESCO Finland
More than one and less than three hours
2.7
10.2
86
442
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.1
10.1
50
193
C07AB02
ATC
metoprolol; systemic
3.5
10.1
39
129
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
17.9
10.0
15
9
Z3231
NOMESCO Finland
Registered nurse
2.7
9.5
69
326
TPH04
NOMESCO Finland
Cathetrisation of vein
2.9
9.5
57
244
I72.3
ICD-10 Finland
Aneurysm and dissection of iliac artery
104.8
9.5
10
*
PD5DG
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
104.8
9.5
10
*
PD1AE
NOMESCO Finland
Ultrasound examination of abdominal aortta
+∞
9.4
9
*
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
+∞
9.4
9
*
FCA50
NOMESCO Finland
Resection and reconstruction of ascending aorta using tube graft
+∞
9.4
9
*
XF402
NOMESCO Finland
ECG with work load test
4.1
9.2
27
73
201
Kela drug reimbursment
Chronic cardiac insufficiency
7.4
9.1
21
31
C03DA01
ATC
spironolactone; oral
3.7
9.1
31
94
WX002
NOMESCO Finland
Sedation and analgesia
3.0
8.9
46
181
M81.9
ICD-10 Finland
Osteoporosis, unspecified
10.1
8.5
16
17
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
4.6
8.4
21
50
FCB50
NOMESCO Finland
Resection of aortic arch and reimplantation of branches
+∞
8.4
8
*
CJG40
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial scleral fixed lens in posterior chamber and iridectomy or iridotomy
+∞
8.4
8
*
Z3226
NOMESCO Finland
Physiotherapist
2.8
8.2
48
202
WX302
NOMESCO Finland
Thoracal epidural anesthesy
6.6
8.1
20
33
H27.0
ICD-10 Finland
Aphakia
46.9
7.8
9
*
R42
ICD-10 Finland
Dizziness and giddiness
2.7
7.7
50
221
XFE00
NOMESCO Finland
Epicardial ultrasonography
12.5
7.7
13
11
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
26.2
7.6
10
*
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
26.2
7.6
10
*
ZXD05
NOMESCO Finland
Urgent procedure
2.4
7.6
78
427
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
83.1
7.5
8
*
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
+∞
7.3
7
*
37870
ICD-8 Finland
Other diseases of eye, Subluxatio et luxatio lentis
+∞
7.3
7
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.5
7.3
27
86
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.7
7.1
24
72
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.9
7.0
21
58
N02AX02
ATC
tramadol; systemic, rectal
2.2
6.9
91
548
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
11.5
6.9
12
11
CG2T4
NOMESCO Finland
Topography assessment of cornea
17.4
6.8
10
6
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
41.5
6.8
8
*
C03CA01
ATC
furosemide; systemic
2.6
6.6
44
196
AA1AD
NOMESCO Finland
CT of head and brain
2.4
6.6
60
309
I48.1
ICD-10 Finland
Persistent atrial fibrillation
7.8
6.5
14
19
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.9
6.5
20
56
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.3
6.5
17
42
AJ2
HP
Reconstruction of the ascending aorta
72.1
6.5
7
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.5
6.4
45
205
C01BD01
ATC
amiodarone; systemic
9.7
6.4
12
13
ZX120
NOMESCO Finland
Intravenous
3.4
6.3
24
78
I72.1
ICD-10 Finland
Aneurysm and dissection of artery of upper extremity
+∞
6.3
6
*
AJ4
HP
Reconstruction of the descending thoracic aorta
+∞
6.3
6
*
PC1BD
NOMESCO Finland
Extensive CT of thoracic aorta
+∞
6.3
6
*
I72.4
ICD-10 Finland
Aneurysm and dissection of artery of lower extremity
+∞
6.3
6
*
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
27.6
6.3
8
*
Z82.4
ICD-10 Finland
Family history of ischaemic heart disease and other diseases of the circulatory system
27.6
6.3
8
*
207
Kela drug reimbursment
Chronic arrhythmias
3.1
6.0
26
91
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
117
380
6.08
36.04
4.9
3.1
813.00
965.26
ng/l
0.34
104
315
77
233
4.77
24.19
3.0
1.9
31.68
29.23
s
2.81
77
228
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
28
32
10.03
22.99
6.6
2.7
0.28
0.28
iu/ml
0.01
17
17
132
657
4.03
19.73
68.4
10.2
1.80
1.16
inr
13.44
121
542
78
289
3.80
17.82
3.9
3.0
2016.66
311.66
ng/l
0.93
65
198
26
56
5.19
11.80
3.7
1.6
159.27
176.98
%
0.61
26
56
27
65
4.65
10.74
3.3
1.5
88.96
97.74
%
0.91
27
65
26
62
4.68
10.46
1.7
1.9
1.18
1.46
g/l
0.55
18
56
52
208
3.03
9.82
21.0
7.2
104.87
104.41
mmol/l
0.26
52
208
31
101
3.45
8.12
26.0
7.6
24.81
25.01
mmol/l
0.11
31
101
74
387
2.46
8.09
2.7
2.1
2.71
2.69
mg/l
0.02
68
347
28
97
3.20
6.63
34.2
10.0
0.64
0.70
%
0.49
28
97
28
99
3.13
6.41
33.8
9.9
1.34
1.52
%
0.54
28
99
68
374
2.25
6.38
2.6
1.7
2.15
1.14
mg/l
1.13
53
294
71
399
2.22
6.31
3.7
2.3
—
—
—
0
0
12
14
9.04
6.15
1.6
1.9
—
—
—
0
0
100
661
2.04
5.67
15.3
6.5
1.18
1.21
mmol/l
3.16
95
623
121
866
2.02
5.39
6.9
6.4
14.70
11.23
umol/l
2.67
115
837
44
215
2.35
5.36
6.4
6.7
1.02
1.04
mmol/l
0.19
44
196
25
92
2.97
5.34
4.1
3.6
24.64
24.27
mmol/l
0.30
25
92
16
35
4.88
5.31
1.4
1.5
—
—
—
0
0
106
734
1.96
5.09
14.2
7.1
1.18
1.21
mmol/l
2.44
90
653
109
776
1.90
4.68
3.9
2.7
—
—
estimate
—
0
0
114
854
1.79
3.88
3.7
2.9
201.41
118.70
ug/l
0.75
105
816
83
573
1.77
3.69
5.0
3.4
33.73
38.78
ng/l
0.17
59
347
127
995
1.77
3.59
8.0
10.9
4.14
4.12
e9/l
0.03
110
868
6
6
10.26
3.52
1.2
1.8
10.32
12.33
umol/l
—
6
6
67
448
1.75
3.26
3.1
2.8
0.21
0.41
e6/l
0.75
53
318
87
628
1.69
3.19
3.2
3.2
35.20
30.34
u/l
0.54
87
599
130
1045
1.71
3.16
5.1
4.1
1172.60
18.92
e6/l
—
5
12
14
50
2.94
3.16
2.5
2.6
—
—
—
0
0
96
721
1.64
2.97
2.9
2.5
78.96
73.33
nmol/l
1.19
87
665
18
77
2.47
2.91
1.7
1.5
—
—
—
0
0
41
245
1.85
2.86
2.4
2.7
2.03
1.94
e6/l
0.04
26
113
18
79
2.41
2.77
3.9
3.4
1.49
1.29
mmol/l
0.11
13
62
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
6
8.51
2.76
1.6
3.0
136.20
91.33
%
—
5
6
31
172
1.95
2.70
2.7
2.8
28.87
32.86
u/l
0.39
31
139
12
41
3.05
2.67
1.3
1.7
—
—
—
0
0
180
1624
2.19
2.66
25.6
12.4
93.86
89.78
ml/min/173m2
1.65
173
1490
60
411
1.66
2.60
1.8
1.5
20.60
20.68
nmol/l
0.01
51
363
12
45
2.77
2.50
1.8
2.4
0.00
0.00
g/l
-0.00
12
45
11
38
3.00
2.46
4.9
2.6
7.87
8.36
kpa
0.39
11
38
35
209
1.82
2.44
1.9
1.6
1132.82
1203.32
nmol/l
0.18
29
165
21
105
2.12
2.41
1.5
3.1
65.70
67.12
g/l
0.34
21
99
10
33
3.14
2.39
1.4
1.2
—
—
—
0
0
27
149
1.94
2.39
3.9
3.0
—
—
—
0
0
147
1263
1.64
2.37
9.4
8.0
80.89
77.91
u/l
0.27
140
1204
39
247
1.72
2.24
1.7
1.8
—
—
—
0
0
11
44
2.59
2.05
7.5
2.5
24.92
24.33
mmol/l
0.21
11
44
13
57
2.37
2.02
1.1
1.3
—
2.28
—
0
12
22
121
1.92
1.98
3.5
2.4
90.17
68.14
ml/min/173m2
1.17
12
59
16
78
2.14
1.97
2.9
2.9
0.59
0.63
%
0.27
16
78
41
274
1.63
1.92
2.6
2.7
0.84
0.84
e6/l
0.00
25
141
9
34
2.72
1.89
3.1
1.9
—
—
—
0
0
82
645
1.46
1.83
2.0
1.9
95.40
95.75
pmol/l
0.03
43
349
185
1728
2.08
1.80
26.2
13.2
33.90
22.85
mg/l
3.18
158
1382
16
81
2.06
1.80
1.3
1.4
—
—
—
0
0
6
18
3.40
1.76
1.0
1.1
—
—
—
0
0
11
48
2.37
1.74
1.1
1.3
—
52.56
—
0
9
20
112
1.87
1.72
5.8
3.7
4.63
4.68
pmol/l
0.11
20
102
7
25
2.86
1.66
1.9
2.2
15.96
15.39
%
—
7
25
19
106
1.88
1.65
1.2
1.5
—
—
—
0
0
17
292
0.54
1.63
1.4
2.0
1.73
1.37
%
0.70
17
265
22
131
1.76
1.57
2.9
5.0
4.83
42.80
ug/l
0.53
12
97
8
33
2.48
1.55
1.0
1.3
—
—
—
0
0
8
33
2.48
1.55
1.0
1.3
—
—
—
0
0
64
497
1.43
1.48
2.8
2.6
61.41
65.30
u/l
0.14
58
476
11
52
2.18
1.47
1.1
1.2
—
—
—
0
0
12
59
2.10
1.47
2.0
1.7
—
—
—
0
0
6
22
2.78
1.44
1.0
1.2
—
—
—
0
0
67
528
1.41
1.42
5.1
3.2
2.31
2.35
mmol/l
1.58
61
494
6
23
2.66
1.38
1.0
1.3
—
—
—
0
0
8
36
2.27
1.26
1.3
1.2
—
—
—
0
0
62
492
1.38
1.25
1.4
1.4
1.01
1.45
u/ml
0.31
19
133
26
174
1.57
1.23
1.8
1.7
—
—
—
0
0
35
472
0.69
1.21
3.8
4.1
27.98
10.54
mg/mmol
0.45
23
307
26
179
1.52
1.10
1.8
1.6
—
—
—
0
0
5
21
2.42
1.09
1.0
1.2
—
—
—
0
0
11
59
1.92
1.09
2.1
2.1
—
—
—
0
0
8
142
0.55
0.98
1.6
1.7
689.11
957.58
mu/l
—
8
119
15
93
1.66
0.97
2.3
2.3
666.13
6202.47
u/l
—
6
34
35
263
1.40
0.97
1.5
1.7
387.75
48347560.38
pmol/l
0.50
28
242
8
138
0.56
0.87
1.8
1.4
—
—
—
0
0
137
1262
1.28
0.83
4.8
3.9
10.99
9.33
mm/h
0.65
125
1189
7
40
1.78
0.72
1.4
1.4
—
—
—
0
0
126
1351
0.81
0.67
3.2
3.4
52.60
43.52
u/l
0.41
121
1306
5
28
1.81
0.66
1.2
1.0
—
—
—
0
0
7
44
1.61
0.66
1.3
1.6
—
—
—
0
0
15
105
1.46
0.62
1.0
1.1
1.44
1.52
g/l
0.78
15
105
5
30
1.68
0.62
1.0
1.6
—
—
—
0
0
15
107
1.43
0.57
1.0
1.1
0.93
0.91
g/l
0.11
15
107
43
363
1.24
0.55
2.0
2.3
—
—
—
0
0
98
898
1.18
0.53
3.9
3.3
0.00
0.00
estimate
-0.00
21
170
26
321
0.78
0.52
1.5
1.3
10.72
4.60
u/ml
—
6
129
97
890
1.18
0.51
3.8
3.2
0.00
0.00
estimate
-0.00
20
173
16
119
1.37
0.50
4.0
4.4
98.63
83.99
ng/l
0.38
16
109
162
1560
1.21
0.44
5.8
4.9
1.79
1.80
mu/l
0.01
152
1469
98
909
1.15
0.43
3.9
3.3
0.00
0.00
estimate
-0.00
19
159
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
9
68
1.34
0.38
1.4
1.2
—
—
—
0
0
39
445
0.85
0.38
3.2
4.0
25.04
21.74
%
0.38
13
186
6
46
1.31
0.33
1.3
1.6
—
—
—
0
0
46
413
1.15
0.31
2.3
2.7
352.46
344.70
umol/l
0.20
41
382
177
1731
1.21
0.31
4.9
5.0
2.68
2.79
mmol/l
0.95
167
1651
31
353
0.86
0.30
1.3
1.3
14.64
21.86
iu/ml
—
7
103
80
747
1.12
0.29
1.6
1.9
1.44
1.43
mmol/l
0.02
71
662
7
57
1.24
0.29
1.0
1.1
—
—
—
0
0
8
63
1.28
0.28
1.1
1.4
0.23
0.22
g/l
—
8
63
16
193
0.81
0.28
1.5
2.3
—
—
—
0
0
8
65
1.24
0.27
1.1
1.4
1.07
1.17
g/l
—
8
65
42
464
0.88
0.27
1.6
1.7
—
—
—
0
0
37
331
1.14
0.26
2.1
2.1
—
—
—
0
0
157
1608
0.89
0.24
4.2
4.3
5.78
5.80
mmol/l
0.09
146
1509
14
115
1.23
0.24
1.0
1.1
—
—
—
0
0
175
1717
1.17
0.24
4.5
4.5
1.31
1.42
mmol/l
4.10
165
1634
5
39
1.29
0.23
1.0
1.1
—
2.40
—
0
11
13
156
0.82
0.22
8.2
7.5
—
—
—
0
0
5
41
1.23
0.22
6.4
3.8
—
1020.00
—
0
5
5
41
1.23
0.22
18.4
5.4
4.06
3.98
mmol/l
—
5
41
0
11
0.00
0.21
0.0
1.1
—
11.36
—
0
11
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
4.3
—
248.60
—
0
10
30
333
0.88
0.21
1.7
2.7
0.57
0.71
ug/l
1.31
18
184
10
123
0.80
0.21
1.4
1.5
0.09
0.35
mg/l
—
5
54
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
175
1721
1.15
0.20
4.6
4.6
4.45
4.66
mmol/l
2.22
165
1647
7
58
1.21
0.18
1.0
1.1
—
—
—
0
0
166
1631
1.11
0.17
4.0
3.9
1.30
1.30
mmol/l
0.03
157
1536
7
63
1.12
0.17
1.3
1.4
—
—
—
0
0
135
1320
1.07
0.14
4.8
4.1
14.99
14.58
pmol/l
1.13
125
1223
32
297
1.09
0.13
1.3
1.5
—
—
—
0
0
9
110
0.81
0.13
1.3
1.3
—
—
—
0
0
14
156
0.89
0.10
1.4
2.3
—
—
—
0
0
5
44
1.14
0.10
1.2
1.2
—
—
—
0
0
5
60
0.83
0.08
1.0
1.7
—
—
—
0
0
5
62
0.80
0.08
1.2
1.1
—
5.94
—
0
12
9
83
1.09
0.07
1.8
1.3
—
—
—
0
0
130
1317
0.96
0.06
3.3
3.6
—
—
—
0
0
39
378
1.04
0.04
4.0
3.6
1.02
1.02
kg/l
1.12
30
244
157
1580
0.97
0.03
5.3
5.5
36.30
38.07
mmol/mol
2.86
152
1518
46
468
0.98
0.01
4.8
3.4
0.00
0.01
estimate
0.50
18
163
52
513
1.02
0.01
4.2
2.4
0.00
0.01
estimate
0.50
14
136
18
174
1.04
0.00
3.0
4.3
32.75
31.00
%
0.29
12
118
67
676
0.99
0.00
4.2
3.1
0.00
0.01
estimate
0.50
17
145
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
60.73
—
0
7
0
8
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
0.30
—
0
8
0
6
0.00
-0.00
0.0
3.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
55.77
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
9.67
—
0
7
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.18
—
0
5
0
8
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.4
—
18.12
—
0
9
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_MARFAN – Marfan's syndrome
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).