Other specified congenital malformation syndromes affecting multiple systems

Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q87
  • Cause of death: ICD-10 Q87

2 out of 7 registries used, show all original rules.

680

4. Check minimum number of events

None

680

5. Include endpoints

None

680

6. Filter based on genotype QC (FinnGen only)

612

Control definitions (FinnGen only)

Control exclude
Q17_OTHER_CONGEN_MALFO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q8
Name in latin
Alia syndromata malformationum congenitarum specificata, systemata multa afficientia

Similar endpoints

List of similar endpoints to Other specified congenital malformation syndromes affecting multiple systems based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5896 2910 2971
Only index persons 4570 2275 2295
Unadjusted period prevalence (%)
Whole population 0.08 0.08 0.08
Only index persons 0.09 0.08 0.09
Median age at first event (years)
Whole population 7.85 8.55 7.03
Only index persons 11.81 12.91 10.72

-FinnGen-

Key figures

All Female Male
Number of individuals 612 331 281
Unadjusted period prevalence (%) 0.12 0.12 0.13
Median age at first event (years) 24.71 25.58 23.69

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
651
Matched controls
6505
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z31.5
ICD-10 Finland
Genetic counselling
20.2
316.0
305
272
Q87.4
ICD-10 Finland
Marfan syndrome
+∞
220.7
199
*
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
37.0
166.2
106
34
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
+∞
138.6
128
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
7.2
114.6
219
430
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
13.8
88.1
86
71
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
4.9
81.3
256
761
ZXE20
NOMESCO Finland
More than three and less than five hours
5.4
71.3
173
410
PD5BD
NOMESCO Finland
Extensive CT of aorta
38.3
69.0
43
12
WX408
NOMESCO Finland
General anesthesy, balanced
4.0
66.1
301
1147
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
5.8
65.0
139
293
ZXD10
NOMESCO Finland
Scheduled procedure
3.9
63.9
351
1510
XF400
NOMESCO Finland
ECG with 12 standard connections
4.5
62.8
199
581
ZXE10
NOMESCO Finland
More than one and less than three hours
3.8
61.6
324
1347
Q87.80
ICD-10 Finland
Alport syndrome
+∞
60.3
57
*
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
20.2
60.1
47
25
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
26.3
59.9
42
17
Z2221
NOMESCO Finland
Medical doctor
3.7
59.0
295
1179
F83
ICD-10 Finland
Mixed specific developmental disorders
9.3
57.7
73
87
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.0
56.3
219
736
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
7.9
55.8
82
117
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.2
55.4
190
583
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.3
54.0
174
509
Q87.09
ICD-10 Finland
Other congenital malformations that mainly affect the appearance of the face
561.2
53.3
52
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
6.2
52.9
100
186
B01AA03
ATC
warfarin; systemic
5.6
52.6
111
229
R4110
NOMESCO Finland
Physiotherapy
3.5
51.0
276
1140
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.2
48.7
113
253
Q87.14
ICD-10 Finland
Noonan's syndrome
+∞
47.5
45
*
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
90.1
45.5
50
6
H01AC01
ATC
somatropin; parenteral
8.5
44.5
60
77
I34.1
ICD-10 Finland
Mitral (valve) prolapse
12.3
44.2
45
39
C01AA05
ATC
digoxin; systemic
12.7
44.1
44
37
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
13.1
43.9
43
35
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
4.3
43.0
127
344
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
42.6
338
1705
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.3
42.0
223
893
C03CA01
ATC
furosemide; systemic
4.0
40.8
137
407
R62.0
ICD-10 Finland
Delayed milestone
6.7
38.9
65
106
Z3226
NOMESCO Finland
Physiotherapist
3.2
38.3
200
788
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
89.7
38.3
42
5
P85
ICPC
Mental retardation
12.5
37.9
38
32
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.6
37.7
98
239
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.5
37.3
78
158
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
7.0
37.2
59
91
XF404
NOMESCO Finland
Ambulatory ECG
4.9
37.0
90
208
Q87.21
ICD-10 Finland
Klippel-Trénaunay-Weber syndrome
+∞
36.8
35
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.2
36.5
82
177
ZXE00
NOMESCO Finland
One hour or less
2.8
36.5
334
1777
TPH07
NOMESCO Finland
Cathetrisation of artery
4.0
36.1
116
332
Z3229
NOMESCO Finland
Other healthcare associate professional
4.1
36.0
113
318
H52.2
ICD-10 Finland
Astigmatism
6.2
35.7
64
112
WX402
NOMESCO Finland
General anaesthesia
2.8
33.0
234
1079
301
Kela drug reimbursment
Growth hormone
13.5
32.5
31
24
WX872
NOMESCO Finland
Intensive care
6.5
32.4
55
91
H52.1
ICD-10 Finland
Myopia
4.7
32.1
80
188
101
Kela drug reimbursment
Anterior pituitary hypofunction
8.6
31.9
42
52
EBA15
NOMESCO Finland
Extraction of multiple teeth
6.4
31.5
54
90
ZXA10
NOMESCO Finland
Bilateral
3.1
31.1
158
605
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
4.3
30.9
87
225
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
30.9
158
607
WX002
NOMESCO Finland
Sedation and analgesia
3.2
30.8
143
519
ZXA00
NOMESCO Finland
Right side
3.0
30.3
170
687
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
162.3
29.9
31
*
Z2446
NOMESCO Finland
Social worker
3.4
29.8
126
431
Q87.19
ICD-10 Finland
Congenital malformation syndromes predominantly associated with short stature
+∞
29.4
28
*
201
Kela drug reimbursment
Chronic cardiac insufficiency
6.5
29.2
49
80
I71.09
ICD-10 Finland
Aortic dissection [regardless of location]
156.9
28.9
30
*
DFF00
NOMESCO Finland
Pure tone audiometry
3.9
28.5
91
258
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
28.0
177
760
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
10.1
27.8
32
33
ZXE40
NOMESCO Finland
More than seven and less than nine hours
6.6
27.8
46
74
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
3.8
27.6
95
283
Z3231
NOMESCO Finland
Registered nurse
2.5
27.5
261
1368
F82
ICD-10 Finland
Specific developmental disorder of motor function
7.2
27.4
42
62
Q21.10
ICD-10 Finland
Persistent ostium secundum
8.0
27.4
38
50
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
6.6
27.3
45
72
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
6.9
27.1
43
66
H27.1
ICD-10 Finland
Dislocation of lens
145.9
26.8
28
*
PD5AD
NOMESCO Finland
CT of aorta
9.1
26.5
33
38
ZXA05
NOMESCO Finland
Left side
2.9
26.4
149
600
RL140, ,
NOMESCO Finland
9.8
26.3
31
33
UDC00
NOMESCO Finland
Ear microscopy
3.9
26.3
86
247
Q87.06
ICD-10 Finland
Velocardiofacial syndrome
+∞
26.2
25
*
Q87.8
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
+∞
26.2
25
*
C07AB07
ATC
bisoprolol; oral
2.5
25.6
230
1167
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
4.4
25.3
68
169
I71.00
ICD-10 Finland
Dissecting aneurysm of aorta (ruptured) [any part]
135.1
24.8
26
*
XFE00
NOMESCO Finland
Epicardial ultrasonography
9.7
24.5
29
31
SPAT1229
SPAT
Assessment of need for aid
6.1
24.4
44
77
A12AA04
ATC
calcium carbonate; oral
8.4
24.0
32
40
TFP20
NOMESCO Finland
Cardiodefibrillation
5.5
24.0
48
93
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
23.9
182
850
I71.01
ICD-10 Finland
Aneurysm of the descending aorta
248.6
23.8
24
*
B01AB05
ATC
enoxaparin; parenteral
2.6
23.7
172
785
ZXD05
NOMESCO Finland
Urgent procedure
2.4
23.4
233
1230
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.7
23.4
80
237
FM2CE, ,
NOMESCO Finland
4.6
23.2
57
132
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.2
23.1
106
378
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
5.9
22.3
41
73
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
22.1
169
788
KA1AE
NOMESCO Finland
Kidney ultrasound examination
6.8
21.9
35
54
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
7.2
21.8
33
48
L28
ICPC
Limited function/disability (L)
3.0
21.4
107
400
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
7.3
21.4
32
46
I50.9
ICD-10 Finland
Heart failure, unspecified
4.7
21.1
50
112
Q89.7
ICD-10 Finland
Multiple congenital malformations, not elsewhere classified
+∞
20.9
20
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
3.5
20.8
78
245
XF640, ,
NOMESCO Finland
8.5
20.6
27
33
R4130
NOMESCO Finland
Speech therapy
4.5
20.6
52
123
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.5
20.4
34
55
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.0
20.3
101
376
R4120
NOMESCO Finland
Occupational therapy
3.5
20.3
74
228
C07AB03
ATC
atenolol; systemic
6.5
19.9
33
53
Q87.16
ICD-10 Finland
Mulibrey nanism
+∞
19.9
19
*
WX892
NOMESCO Finland
Monitored bed care
3.3
19.8
80
263
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
5.9
19.6
36
64
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
19.4
170
838
K84
ICPC
Heart disease other
8.2
19.3
26
33
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.4
19.2
74
236
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
20.8
19.2
28
14
A28
ICPC
Limited function/disability NOS
3.1
19.2
87
307
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.9
19.1
60
167
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
5.7
19.0
36
66
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
6.8
18.9
30
46
SAA04
NOMESCO Finland
Special examination of mouth
3.1
18.9
89
321
7598B
ICD-9 Finland
Other and unspecified congenital anomalies, Other specified anomalies[SYNDROMA MARFAN]
+∞
18.8
18
*
Q87.1
ICD-10 Finland
Congenital malformation syndromes predominantly associated with short stature
+∞
18.8
18
*
RS222, ,
NOMESCO Finland
7.3
18.8
28
40
Q25.0
ICD-10 Finland
Patent ductus arteriosus
7.6
18.8
27
37
Q35.1
ICD-10 Finland
Cleft hard palate
103.0
18.7
20
*
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
6.6
18.5
30
47
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.0
18.4
54
143
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.3
18.4
75
248
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
3.0
18.0
89
329
A11CC03
ATC
alfacalcidol; systemic
5.5
17.9
35
66
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
23.6
17.9
25
11
Q87.30
ICD-10 Finland
Syndrome Beckwith-Wiedemann
+∞
17.8
17
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
5.7
17.6
33
60
ZXD20
NOMESCO Finland
Day surgery
2.7
17.5
102
412
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.5
17.4
64
198
XF402
NOMESCO Finland
ECG with work load test
3.6
17.4
60
178
H52.0
ICD-10 Finland
Hypermetropia
4.2
17.2
47
118
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
26.4
17.0
23
9
TJD20
NOMESCO Finland
Change of gastrostomy tube
14.6
16.9
28
20
C09CA01
ATC
losartan; oral
2.5
16.8
118
523
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
6.7
16.7
27
42
TK800
NOMESCO Finland
Hemodialysis
6.9
16.7
26
39
Q82.50
ICD-10 Finland
Naevus flammeus
174.1
16.6
17
*
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
6.7
16.3
26
40
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
13.2
16.3
28
22
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.9
16.2
50
137
4122
FHL
Tympanostomy (tympanic tube)
5.5
16.2
32
61
Z97.4
ICD-10 Finland
Presence of external hearing-aid
6.2
16.2
28
47
N03AX14
ATC
levetiracetam; systemic
4.6
16.1
39
89
Z94.0
ICD-10 Finland
Kidney transplant status
6.6
15.9
26
41
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
6.2
15.7
27
45
Q87.03
ICD-10 Finland
Syndrome Goldenhar
+∞
15.7
15
*
Q87.38
ICD-10 Finland
Syndrome Weaver
+∞
15.7
15
*
Q87.26
ICD-10 Finland
VATER association
+∞
15.7
15
*
75988
ICD-8 Finland
Congenital syndromes affecting multiple systems, Aliae definitae
+∞
15.7
15
*
DFF20
NOMESCO Finland
Audiometry for children
5.8
15.7
29
52
AA1AD
NOMESCO Finland
CT of head and brain
2.3
15.5
144
721
XA800
NOMESCO Finland
Neuropsychological investigation
3.0
15.4
71
252
N18.8
ICD-10 Finland
Other chronic renal failure
7.0
14.9
23
34
RL130, ,
NOMESCO Finland
7.0
14.9
23
34
127
Kela drug reimbursment
Transplant complication
5.2
14.9
31
62
C03DA01
ATC
spironolactone; oral
3.1
14.9
66
229
WX882
NOMESCO Finland
High dependency care
3.2
14.9
61
202
GD1AD
NOMESCO Finland
Thorax CT examination
3.7
14.9
48
136
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
32.5
14.9
19
6
K03.66
ICD-10 Finland
Tooth plaque
2.4
14.9
113
518
I71.1
ICD-10 Finland
Thoracic aortic aneurysm, ruptured
58.0
14.8
17
*
R31
ICD-10 Finland
Unspecified haematuria
3.4
14.8
55
171
H50.0
ICD-10 Finland
Convergent concomitant strabismus
5.8
14.7
27
48
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.5
14.7
52
157
Q87.0
ICD-10 Finland
Congenital malformation syndromes predominantly affecting facial appearance
+∞
14.6
14
*
PD5BG
NOMESCO Finland
MRI examination of thoracal and abdominal aortta with high intensity magnet
81.9
14.6
16
*
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
153.2
14.5
15
*
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
153.2
14.5
15
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.8
14.5
45
124
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.1
14.5
65
227
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
14.5
325
2232
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
12.9
14.5
25
20
R1260
NOMESCO Finland
Evaluation of communicative skills
5.7
14.4
27
49
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
11.7
14.4
26
23
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
4.1
14.3
40
102
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.9
14.3
73
274
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.3
14.3
55
175
TLC00
NOMESCO Finland
Insertion of intrauterine device
3.1
14.2
62
213
XF600
NOMESCO Finland
Bloodpressure measurement
2.7
14.0
78
307
J01MA12
ATC
levofloxacin; systemic
2.5
14.0
97
426
L04AD02
ATC
tacrolimus; systemic
5.7
13.9
26
47
RT150, ,
NOMESCO Finland
6.4
13.8
23
37
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
13.7
74
286
RS220, ,
NOMESCO Finland
5.1
13.7
29
59
Q35.71
ICD-10 Finland
Submucous cleft palate
76.7
13.6
15
*
Q87.15
ICD-10 Finland
Prader-Willi syndrome
+∞
13.6
13
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.2
13.6
145
765
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
26.4
13.4
18
7
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
6.5
13.3
22
35
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
10.8
13.3
25
24
H33.0
ICD-10 Finland
Retinal detachment with retinal break
5.5
13.3
26
49
ZX120
NOMESCO Finland
Intravenous
2.8
13.3
73
285
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
4.0
13.2
38
99
Q27.4
ICD-10 Finland
Congenital phlebectasia
40.9
13.2
16
*
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
3.1
13.2
57
195
R5120
NOMESCO Finland
Preparation of an aid
5.6
13.1
25
46
UKC02
NOMESCO Finland
Cystoscopy
2.8
13.1
70
269
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
6.1
13.1
23
39
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
23.1
12.9
18
8
M05BA04
ATC
alendronic acid; oral
4.3
12.8
33
79
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
14.4
12.8
21
15
A03FA02
ATC
cisapride; oral, rectal
3.5
12.8
45
135
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
4.9
12.7
28
59
UGC02
NOMESCO Finland
Rigid bronchoscopy
11.3
12.6
23
21
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
12.6
179
1047
Q87.28
ICD-10 Finland
Congenital malformation syndromes predominantly involving limbs
+∞
12.5
12
*
Q87.04
ICD-10 Finland
Syndrome Robin
+∞
12.5
12
*
FCC50
NOMESCO Finland
Resection and reconstruction of descending aorta using tube graft
+∞
12.5
12
*
7597A
ICD-9 Finland
Other and unspecified congenital anomalies, Multiple congenital anomalies, so described
+∞
12.5
12
*
PD5CM
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
12.5
12
*
Q87.5
ICD-10 Finland
Other congenital malformation syndromes with other skeletal changes
+∞
12.5
12
*
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
11.9
12.4
22
19
XKC03
NOMESCO Finland
Water cystometry
5.5
12.4
24
45
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.0
12.3
56
197
H61.2
ICD-10 Finland
Impacted cerumen
3.0
12.3
57
203
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.6
12.3
41
119
WX140
NOMESCO Finland
Parabulbar anesthesy
4.7
12.2
28
61
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.1
12.1
145
796
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.8
12.1
63
239
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
12.0
117
594
F80.1
ICD-10 Finland
Expressive language disorder
4.4
11.8
30
71
C07AA07
ATC
sotalol; systemic
9.2
11.8
24
27
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
10.8
11.8
22
21
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.4
11.8
43
132
N02AX02
ATC
tramadol; systemic, rectal
1.9
11.7
214
1355
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
11.6
196
1208
62
HP
Catheterization and pressure measurement of the right side of the heart
66.1
11.6
13
*
FCA75
NOMESCO Finland
Valve-sparing repair of aortic root (David, Yacoub)
66.1
11.6
13
*
K78
ICPC
Atrial fibrillation/flutter
4.4
11.6
29
68
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
11.5
134
727
D82.1
ICD-10 Finland
Di George syndrome
+∞
11.5
11
*
75980
ICD-8 Finland
Congenital syndromes affecting multiple systems, Syndroma Marfan, arachnodactylia
+∞
11.5
11
*
7598X
ICD-9 Finland
Other and unspecified congenital anomalies, Other specified anomalies[ANOMALIAE CONGENITAE ALIAE DEFINITAE]
+∞
11.5
11
*
FCD60
NOMESCO Finland
Resection of thoracoabdominal aorta and reimplantation of branches
+∞
11.5
11
*
Q87.84
ICD-10 Finland
Williams syndrome
+∞
11.5
11
*
A90
ICPC
Congenital anomaly NOS/multiple
122.0
11.5
12
*
R5110, ,
SPAT
3.3
11.4
44
140
114
Kela drug reimbursment
Glaucoma
4.0
11.4
32
82
Z50.5
ICD-10 Finland
Speech therapy
3.4
11.3
42
131
K83
ICPC
Heart valve disease NOS
17.4
11.2
17
10
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
17.4
11.2
17
10
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
4.2
11.2
30
74
JDB10
NOMESCO Finland
Percutaneous gastrostomy
8.3
11.2
24
30
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
3.9
11.1
33
88
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.9
11.1
33
88
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
3.8
11.1
34
93
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
5.1
11.1
23
46
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
3.3
11.0
41
128
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.4
11.0
82
371
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.6
11.0
37
108
ZXC12
NOMESCO Finland
Pulse colorlaser
44.1
10.9
13
*
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
8.5
10.9
23
28
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.6
10.7
36
105
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
61.0
10.6
12
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.0
10.6
49
174
EB1WA, ,
NOMESCO Finland
11.5
10.6
19
17
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.7
10.6
57
220
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.9
10.5
23
48
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
4.0
10.5
30
78
Z2445
NOMESCO Finland
Psychologist
2.4
10.5
75
333
PDG51
NOMESCO Finland
Bypass from aorta to iliac artery for aneurysm
111.7
10.4
11
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.0
10.4
48
170
I71.6
ICD-10 Finland
Thoracoabdominal aortic aneurysm, without mention of rupture
+∞
10.4
10
*
26
HP
Aortic root """"composite graft""""
+∞
10.4
10
*
Q87.31
ICD-10 Finland
Syndrome Sotos
+∞
10.4
10
*
K99
ICPC
Cardiovascular disease other
12.3
10.4
18
15
NF1AA
NOMESCO Finland
Hip X-ray examination
3.2
10.4
42
138
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.8
10.4
32
88
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
4.1
10.3
28
70
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
23.8
10.3
14
6
N03AF02
ATC
oxcarbazepine; oral
3.3
10.1
38
119
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.1
10.1
28
71
CG2T4
NOMESCO Finland
Topography assessment of cornea
9.3
10.1
20
22
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.4
10.1
73
326
ENC80
NOMESCO Finland
Plastic operation of soft palate for voice distubance
40.7
10.0
12
*
S97
ICPC
Chronic ulcer skin
3.5
10.0
34
100
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
7.8
10.0
22
29
R50.9
ICD-10 Finland
Fever, unspecified
1.9
9.9
141
817
M41.4
ICD-10 Finland
Neuromuscular scoliosis
17.0
9.9
15
9
H50.30
ICD-10 Finland
Intermittent esotropy
5.3
9.9
20
39
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
5.0
9.8
21
43
B02AA02
ATC
tranexamic acid; systemic
2.2
9.8
91
451
SPAT1262
SPAT
Handing over of treatment supplies
2.2
9.8
85
410
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.9
9.8
46
165
PD5DG
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
55.8
9.7
11
*
Q76.30
ICD-10 Finland
Hemivertebra fusion or failure of segmentation with scoliosis
55.8
9.7
11
*
I72.3
ICD-10 Finland
Aneurysm and dissection of iliac artery
55.8
9.7
11
*
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
4.4
9.6
24
56
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
8.6
9.6
20
24
RD210, ,
NOMESCO Finland
3.0
9.6
43
150
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.3
9.6
78
366
Q99.8
ICD-10 Finland
Other specified chromosome abnormalities
15.3
9.5
15
10
Q17.2
ICD-10 Finland
Microtia
101.4
9.4
10
*
Z82.6
ICD-10 Finland
Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
101.4
9.4
10
*
EHC30
NOMESCO Finland
Reconstruction of palate
101.4
9.4
10
*
Q67.0
ICD-10 Finland
Facial asymmetry
101.4
9.4
10
*
EEC05
NOMESCO Finland
Le Fort I osteotomy
17.8
9.4
14
8
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.9
9.4
28
75
Q27.0
ICD-10 Finland
Congenital absence and hypoplasia of umbilical artery
+∞
9.4
9
*
CJG40
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial scleral fixed lens in posterior chamber and iridectomy or iridotomy
+∞
9.4
9
*
PD1AE
NOMESCO Finland
Ultrasound examination of abdominal aortta
+∞
9.4
9
*
Q87.82
ICD-10 Finland
Zellweger syndrome
+∞
9.4
9
*
Q87.10
ICD-10 Finland
Aarskog syndrome
+∞
9.4
9
*
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.7
9.4
51
198
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.7
9.4
51
198
H81
ICPC
Excessive ear wax
2.2
9.3
84
412
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
7.9
9.2
20
26
207
Kela drug reimbursment
Chronic arrhythmias
2.8
9.2
47
177
H26.4
ICD-10 Finland
After-cataract
3.4
9.1
33
101
EB1MA
NOMESCO Finland
Cephalometry with X-ray
2.4
9.1
65
288
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
9.2
9.1
18
20
31
HP
Congenital heart failure surgery
18.9
9.0
13
7
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.0
9.0
39
134
R5140
NOMESCO Finland
Monitoring the use of the aid
2.4
8.9
61
265
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
4.8
8.9
20
43
H50.31
ICD-10 Finland
Intermittent exotropia
4.1
8.8
24
60
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
7.3
8.8
20
28
A06AD11
ATC
lactulose; oral
2.4
8.8
60
261
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.5
8.7
56
236
K07.24
ICD-10 Finland
Open bite
3.6
8.7
29
84
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.2
8.7
73
347
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
50.6
8.7
10
*
Q16.1
ICD-10 Finland
Congenital absence, atresia and stricture of auditory canal (external)
50.6
8.7
10
*
Q27.9
ICD-10 Finland
Congenital malformation of peripheral vascular system, unspecified
50.6
8.7
10
*
I50.0
ICD-10 Finland
Congestive heart failure
4.5
8.7
21
48
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
8.7
72
341
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
8.7
210
1422
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.0
8.6
39
137
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
10.2
8.6
16
16
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
4.3
8.5
22
53
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
27.9
8.5
11
*
Q27.3
ICD-10 Finland
Peripheral arteriovenous malformation
20.3
8.5
12
6
NFK20
NOMESCO Finland
Epiphysiodesis of femur
20.3
8.5
12
6
WX722
NOMESCO Finland
PEEP
3.2
8.5
33
106
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
3.0
8.5
38
133
205
Kela drug reimbursment
Chronic hypertension
2.2
8.4
74
358
QBA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of trunk
91.1
8.4
9
*
Q35.3
ICD-10 Finland
Cleft soft palate
91.1
8.4
9
*
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
13.0
8.4
14
11
Q21.30
ICD-10 Finland
Tetralogy of Fallot
13.0
8.4
14
11
Q23.11
ICD-10 Finland
Bicuspid aortic valve
5.0
8.4
18
37
JAH00
NOMESCO Finland
Laparotomy
4.1
8.4
23
58
FCB50
NOMESCO Finland
Resection of aortic arch and reimplantation of branches
+∞
8.3
8
*
Q87.27
ICD-10 Finland
CHARGE association
+∞
8.3
8
*
Q79.8
ICD-10 Finland
Other congenital malformations of musculoskeletal system
+∞
8.3
8
*
H25.1
ICD-10 Finland
Senile nuclear cataract
2.4
8.3
60
267
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
8.3
81
409
C07AB02
ATC
metoprolol; systemic
2.2
8.2
68
321
DAX08
NOMESCO Finland
Fitting of hearing aid
3.8
8.2
25
68
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.2
8.2
73
355
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.5
8.2
20
46
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
4.5
8.2
20
46
Q35.9
ICD-10 Finland
Cleft palate, unspecified
33.8
8.1
10
*
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
33.8
8.1
10
*
J01MA02
ATC
ciprofloxacin; systemic
1.7
8.1
171
1113
U04
ICPC
Incontinence urine
3.6
8.0
26
74
4451
FHL
Guitar cutting
2.9
8.0
38
137
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
3.4
8.0
29
89
RT160, ,
NOMESCO Finland
7.4
8.0
18
25
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.5
7.9
19
43
TQW40
NOMESCO Finland
Remowal of suture of skin
2.7
7.9
42
161
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
6.7
7.9
19
29
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
13.2
7.9
13
10
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
7.9
497
4241
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
8.6
7.8
16
19
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.4
7.8
52
224
H05BX01
ATC
cinacalcet; oral
15.2
7.7
12
8
FCA50
NOMESCO Finland
Resection and reconstruction of ascending aorta using tube graft
45.5
7.7
9
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.8
7.7
39
146
WZC30
NOMESCO Finland
Teaching
2.0
7.7
94
515
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
4.6
7.7
18
40
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.6
7.7
18
40
I48.1
ICD-10 Finland
Persistent atrial fibrillation
6.8
7.6
18
27
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
8.2
7.6
16
20
U07
ICPC
Urine symptom/complaint other
2.4
7.6
52
226
RT490, ,
NOMESCO Finland
12.0
7.6
13
11
61
HP
Catheterization and pressure measurement of the left side of the heart
12.0
7.6
13
11
Q27.88
ICD-10 Finland
Other specified congenital malformation of peripheral vascular system
25.3
7.6
10
*
M41.5
ICD-10 Finland
Other secondary scoliosis
25.3
7.6
10
*
602
Kela drug reimbursment
Children's severe malnutrition
3.4
7.6
27
82
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
4.2
7.6
20
49
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
4.2
7.6
20
49
M21.7
ICD-10 Finland
Unequal limb length (acquired)
9.0
7.6
15
17
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
9.0
7.6
15
17
V03AE01
ATC
polystyrene sulfonate; oral
10.2
7.6
14
14
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.4
7.5
54
240
H40.0
ICD-10 Finland
Glaucoma suspect
2.8
7.5
36
131
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
7.5
62
293
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.4
7.5
50
215
C02AC05
ATC
moxonidine; oral
4.5
7.5
18
41
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
4.5
7.5
18
41
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
80.9
7.4
8
*
4364
FHL
Pharyngeal tongue plastic
80.9
7.4
8
*
TCG10
NOMESCO Finland
Removal of sutures from cornea
80.9
7.4
8
*
JDB00
NOMESCO Finland
Gastrostomy
13.5
7.4
12
9
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.7
7.3
23
64
J01FF01
ATC
clindamycin; systemic
1.7
7.3
140
882
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
7.3
95
531
B03XA02
ATC
darbepoetin alfa; parenteral
6.9
7.3
17
25
E23.02
ICD-10 Finland
Neurosecretory dysfunction of the growth hormone
11.0
7.3
13
12
37870
ICD-8 Finland
Other diseases of eye, Subluxatio et luxatio lentis
+∞
7.3
7
*
Q87.00
ICD-10 Finland
Syndrome Treacher Collins
+∞
7.3
7
*
I72.4
ICD-10 Finland
Aneurysm and dissection of artery of lower extremity
+∞
7.3
7
*
BF10A, ,
NOMESCO Finland
+∞
7.3
7
*
Q78.9
ICD-10 Finland
Osteochondrodysplasia, unspecified
+∞
7.3
7
*
Q87.23
ICD-10 Finland
Rubinstein-Taybi syndrome
+∞
7.3
7
*
7844L
ICD-9 Finland
Symptoms involving head and neck, Voice disturbance[RINOPHONIA SEU RHINOLALIA]
+∞
7.3
7
*
N03AX16
ATC
[U] pregabalin
1.9
7.3
105
608
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
7.2
81
430
I50.1
ICD-10 Finland
Left ventricular failure
4.4
7.2
18
42
Q66.0
ICD-10 Finland
Talipes equinovarus
15.9
7.2
11
7
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
15.9
7.2
11
7
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
15.9
7.2
11
7
EBB10
NOMESCO Finland
Insertion of dental implant
7.4
7.2
16
22
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.9
7.2
33
117
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
7.2
69
346
5253
FHL
Cardiac lung machine
30.3
7.2
9
*
JN4AD
NOMESCO Finland
Body CT examination
2.4
7.1
48
207
H27.0
ICD-10 Finland
Aphakia
20.3
7.1
10
5
CKD60
NOMESCO Finland
Anterior vitrectomy
20.3
7.1
10
5
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.4
7.1
50
1017
N30.0
ICD-10 Finland
Acute cystitis
1.9
7.1
98
559
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
12.2
7.1
12
10
H47.2
ICD-10 Finland
Optic atrophy
12.2
7.1
12
10
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
12.2
7.1
12
10
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
12.2
7.1
12
10
KFH10
NOMESCO Finland
Orchiopexy
8.9
7.1
14
16
J01EA01
ATC
trimethoprim; systemic
1.8
7.1
122
746
K29
ICPC
Cardiovascular sympt/complt other
3.9
7.0
20
52
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.9
7.0
20
52
E34.35
ICD-10 Finland
Abnormal growth retardation
3.4
6.9
24
72
JN3AD
NOMESCO Finland
Abdominal CT examination
2.1
6.8
67
339
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
9.4
6.8
13
14
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.6
6.8
39
156
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
4.3
6.8
17
40
Q76.48
ICD-10 Finland
Congenital anomalies of other vertebrae, not associated with scoliosis
40.5
6.8
8
*
Q42.2
ICD-10 Finland
Congenital absence, atresia and stenosis of anus with fistula
40.5
6.8
8
*
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
40.5
6.8
8
*
7373A
ICD-9 Finland
Curvature of spine, Kyphoscoliosis and scoliosis
40.5
6.8
8
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.8
6.8
34
127
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.5
6.7
23
68
A46
ICD-10 Finland
Erysipelas
2.1
6.7
62
306
R42
ICD-10 Finland
Dizziness and giddiness
1.8
6.7
103
607
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
7.3
6.7
15
21
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
22.8
6.7
9
*
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
22.8
6.7
9
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
6.7
43
182
137
Kela drug reimbursment
Uraemia requiring dialysis
6.5
6.7
16
25
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.9
6.7
31
111
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
3.6
6.6
21
59
A08
ICPC
Swelling
3.0
6.6
28
95
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.0
6.6
77
415
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
12.4
6.6
11
9
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
12.4
6.6
11
9
TKC20
NOMESCO Finland
Catheterisation of bladder
2.8
6.6
33
123
NF1DA
NOMESCO Finland
X-ray of hips
4.2
6.6
17
41
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
4.2
6.6
17
41
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
3.0
6.5
29
101
H26.2
ICD-10 Finland
Complicated cataract
6.9
6.5
15
22
K03.00
ICD-10 Finland
Approximal wear
2.1
6.5
64
324
NF3AA
NOMESCO Finland
Femur X-ray examination
3.7
6.5
20
55
Z50.1
ICD-10 Finland
Other physical therapy
3.0
6.5
28
96
K00.00
ICD-10 Finland
Hypodontia
3.0
6.5
28
96
JFF26
NOMESCO Finland
Sigmoidostomy
70.5
6.4
7
*
RT290, ,
NOMESCO Finland
70.5
6.4
7
*
AJ2
HP
Reconstruction of the ascending aorta
70.5
6.4
7
*
Q14.8
ICD-10 Finland
Other congenital malformations of posterior segment of eye
70.5
6.4
7
*
F70
ICD-10 Finland
Mild mental retardation
70.5
6.4
7
*
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
2.1
6.4
64
326
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
14.5
6.4
10
7
196
Kela drug reimbursment
Paricalcitol and cinacalcet
14.5
6.4
10
7
K59.09
ICD-10 Finland
Constipation, unspecified
2.3
6.4
46
205
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
4.1
6.4
17
42
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
6.4
325
2578
H50.1
ICD-10 Finland
Divergent concomitant strabismus
6.6
6.4
15
23
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.8
6.4
31
114
C01BD01
ATC
amiodarone; systemic
6.0
6.3
16
27
RK110, ,
NOMESCO Finland
6.0
6.3
16
27
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
3.3
6.3
23
71
RS221, ,
NOMESCO Finland
3.3
6.3
23
71
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
9.4
6.3
12
13
C08CA01
ATC
amlodipine; oral
1.7
6.3
128
819
P94.2
ICD-10 Finland
Congenital hypotonia
18.2
6.3
9
5
ZZH22
NOMESCO Finland
Graft of patients own bone, block
18.2
6.3
9
5
AA6AD
NOMESCO Finland
Cranial bones CT examination
18.2
6.3
9
5
Q78.88
ICD-10 Finland
Other specified osteochondrodysplasias
+∞
6.3
6
*
Q87.17
ICD-10 Finland
Russel-Silver syndrome
+∞
6.3
6
*
90492, ,
NOMESCO Finland
+∞
6.3
6
*
Q42.3
ICD-10 Finland
Congenital absence, atresia and stenosis of anus without fistula
+∞
6.3
6
*
AJ4
HP
Reconstruction of the descending thoracic aorta
+∞
6.3
6
*
Q87.22
ICD-10 Finland
Nail-patella syndrome
+∞
6.3
6
*
Q71.4
ICD-10 Finland
Longitudinal reduction defect of radius
+∞
6.3
6
*
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
7.1
6.2
14
20
B05DA
ATC
Isotonic solutions
7.1
6.2
14
20
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
26.9
6.2
8
*
XX4AW, ,
NOMESCO Finland
3.7
6.2
19
52
N05BA09
ATC
clobazam; oral
5.1
6.2
18
36
K59.0
ICD-10 Finland
Constipation
2.5
6.2
37
151
N05AX08
ATC
risperidone; systemic
2.2
6.2
53
254
J01DB01
ATC
cefalexin; oral
1.6
6.2
507
4446
I48.2
ICD-10 Finland
Chronic atrial fibrillation
5.4
6.2
17
32
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
5.8
6.2
16
28
H26.02
ICD-10 Finland
Presenil cataract
3.8
6.1
18
48
H66.9
ICD-10 Finland
Otitis media, unspecified
1.7
6.1
117
736
7505
FHL
Funicular lysis and orchidopexy
12.7
6.1
10
8
TLC02
NOMESCO Finland
Simple extraction of IUD
2.8
6.1
30
111
N03AG01
ATC
valproic acid; systemic, rectal
2.2
6.1
50
236
RK320, ,
NOMESCO Finland
8.7
6.1
12
14
PHD99
NOMESCO Finland
Resection of other vein
3.0
6.1
26
89
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
10.1
6.0
11
11
J35.1
ICD-10 Finland
Hypertrophy of tonsils
2.6
6.0
33
129
J01DA01
ATC
[U] cefalexin
1.5
6.0
308
2435

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
261
907
4.13
65.25
5.1
4.4
1030.80
806.29
ng/l
0.51
231
735
117
255
5.37
52.16
3.8
5.2
147.19
160.64
ng/l
0.16
110
227
331
1736
2.84
37.47
34.8
8.4
1.46
1.13
inr
13.02
281
1447
211
882
3.06
36.18
12.5
10.7
1.19
1.21
mmol/l
0.25
204
842
128
414
3.60
33.23
8.3
7.4
100.76
68.23
ng/l
1.68
123
393
195
832
2.92
31.67
4.5
2.9
12.50
14.40
umol/l
3.54
190
790
173
704
2.98
30.50
4.5
3.0
20.72
23.93
%
2.98
168
678
377
2288
2.54
29.37
19.2
11.0
1.21
1.22
mmol/l
3.03
362
2170
178
769
2.81
27.81
4.6
2.8
2.36
2.42
g/l
0.84
172
728
395
2497
2.48
27.46
17.7
10.6
1.21
1.22
mmol/l
1.90
361
2255
230
1145
2.56
26.91
6.2
4.4
—
—
—
0
0
355
2160
2.41
26.57
8.4
9.3
—
—
—
0
0
337
2014
2.39
26.14
7.7
6.9
36.68
37.48
g/l
1.71
326
1926
289
1655
2.34
24.23
3.4
2.8
—
—
—
0
0
245
1306
2.40
24.23
3.1
2.8
—
—
—
0
0
428
2922
2.35
23.31
8.7
8.8
0.64
0.67
%
0.53
411
2780
257
1421
2.33
23.15
3.1
2.9
2.87
2.57
mg/l
0.77
228
1270
428
2928
2.34
23.11
8.6
8.7
3.17
3.00
%
0.81
412
2791
244
1331
2.33
22.57
8.6
4.3
7.39
7.39
ph
1.50
177
918
427
2936
2.32
22.51
8.7
8.8
8.89
8.50
%
2.51
411
2802
63
163
4.17
22.20
1.8
2.3
1.26
1.27
g/l
0.02
52
151
160
726
2.59
22.15
16.5
12.3
—
—
—
0
0
443
3140
2.28
21.02
8.7
8.6
0.57
0.55
e9/l
0.96
390
2668
173
836
2.45
20.82
4.6
3.8
1321.75
531.69
ng/l
0.84
134
506
140
612
2.64
20.80
17.9
10.4
104.91
104.79
mmol/l
0.10
140
612
174
845
2.44
20.70
7.6
8.4
0.81
0.82
mmol/l
0.07
169
815
442
3141
2.26
20.68
8.8
8.7
0.04
0.04
e9/l
2.11
388
2663
110
428
2.89
20.43
17.9
11.7
0.18
0.61
mmol/l
0.42
95
364
430
3035
2.22
20.26
8.7
8.7
28.49
31.87
%
8.35
417
2922
110
434
2.84
19.89
18.1
11.6
7.40
7.41
ph
0.49
46
208
96
357
2.98
19.30
10.7
18.8
1.36
1.13
mg/l
1.44
90
349
447
3243
2.20
19.10
9.4
9.3
0.21
0.20
e9/l
0.33
397
2810
444
3216
2.19
19.01
8.8
8.7
1.86
2.14
e9/l
4.76
396
2804
110
447
2.76
18.75
2.7
5.2
81.47
70.30
e9/l
1.31
69
297
420
2986
2.14
18.75
8.6
8.6
55.85
53.37
%
4.10
407
2890
279
1705
2.11
18.65
5.7
3.7
33.88
43.35
e6/l
0.38
213
1259
148
700
2.44
18.44
2.5
2.1
—
—
—
0
0
417
2985
2.10
17.90
12.1
6.8
6.09
6.35
mmol/l
2.14
409
2786
207
1145
2.18
17.74
3.3
3.3
2.08
1.10
mg/l
1.67
160
863
316
2051
2.05
17.68
6.7
4.4
139.27
50.36
e6/l
0.40
225
1344
459
3416
2.16
17.65
11.9
11.4
3.82
3.78
e9/l
0.18
399
2904
349
2366
2.02
17.10
3.6
3.1
—
—
estimate
—
0
0
157
799
2.27
16.35
9.7
10.3
7.36
7.37
ph
1.53
117
517
481
3719
2.12
15.68
9.8
7.5
90.73
91.22
u/l
0.06
466
3553
56
170
3.51
15.67
9.1
8.0
24.67
24.09
mmol/l
0.55
56
165
152
781
2.23
15.38
9.6
10.3
1.92
1.23
mmol/l
1.62
139
659
247
1525
2.00
15.34
5.6
3.6
0.21
0.32
e6/l
0.74
187
1079
216
1272
2.04
15.32
2.3
2.3
318.07
269.30
u/l
0.26
208
1224
196
1115
2.08
15.26
4.9
2.9
5.73
6.79
e6/l
0.44
179
995
345
2410
1.92
14.66
4.4
3.1
75.87
71.19
nmol/l
2.89
327
2268
350
2471
1.90
14.25
7.7
7.4
15.89
15.54
umol/l
0.08
334
2359
207
1239
1.98
13.78
3.7
2.5
—
—
—
0
0
165
919
2.06
13.38
4.1
3.4
2.08
2.27
e6/l
0.14
91
440
278
1850
1.88
13.35
9.4
7.7
—
—
—
0
0
241
1533
1.91
13.30
4.5
3.2
2.35
2.37
mmol/l
0.92
227
1430
129
660
2.19
13.01
9.4
10.3
24.03
23.63
mmol/l
0.98
129
660
187
1107
1.97
12.69
1.9
1.5
22.56
20.23
nmol/l
1.04
168
981
131
685
2.14
12.47
13.4
9.8
7.40
7.41
ph
0.65
119
550
383
2857
1.82
12.37
13.3
11.7
0.00
0.00
e9/l
0.53
306
2244
168
972
1.98
12.11
4.1
3.2
0.79
0.77
e6/l
0.04
94
494
130
702
2.06
11.29
2.5
1.8
—
—
—
0
0
24
49
5.04
11.27
39.8
51.9
6.35
6.82
ug/l
0.71
24
43
38
118
3.36
10.27
3.1
2.8
135.77
131.60
g/l
0.50
30
97
49
178
2.89
10.19
1.5
2.4
—
—
—
0
0
110
583
2.07
9.97
12.4
9.9
—
—
—
0
0
64
270
2.52
9.96
1.9
3.4
64.91
66.54
g/l
0.90
64
260
259
1802
1.72
9.94
2.2
1.9
96.20
97.33
pmol/l
0.14
138
965
164
1006
1.84
9.65
4.8
2.9
557.91
565.57
mosm/kgh2o
0.14
148
882
213
1418
1.74
9.48
3.7
2.9
24.78
38.26
ng/l
0.58
141
762
104
555
2.04
9.22
3.1
4.0
0.23
0.22
g/l
0.45
99
530
43
154
2.92
9.18
1.5
1.9
26.21
23.77
ng/l
0.24
43
154
56
234
2.52
8.89
4.4
7.0
463.72
319.77
mg/l
0.50
36
163
413
3314
1.67
8.82
6.1
4.0
455.67
428.29
e6/l
0.02
15
35
29
85
3.52
8.58
8.8
5.4
7.96
7.25
pmol/l
0.16
29
85
68
317
2.28
8.48
3.4
2.9
0.13
0.14
e6/l
0.04
63
300
439
3599
1.67
8.44
6.3
4.2
—
3.13
—
0
8
622
5708
2.99
8.37
27.6
14.1
73.68
68.74
umol/l
1.42
616
5652
92
486
2.04
8.36
1.9
1.6
1067.50
1157.46
nmol/l
0.46
73
387
32
105
3.15
7.95
7.1
10.6
1.31
1.19
mmol/l
0.46
32
89
65
307
2.24
7.86
11.4
10.0
127.58
131.58
g/l
0.61
65
302
303
2302
1.59
7.66
4.4
3.2
6.13
6.21
ph
0.63
158
1224
375
3000
1.59
7.56
4.9
3.5
126.37
83.15
ug/l
1.44
359
2872
29
93
3.21
7.48
6.9
4.8
—
—
—
0
0
16
21
7.78
7.42
1.7
1.5
1.39
0.67
iu/ml
—
11
8
26
81
3.30
7.03
1.6
3.4
1.44
1.45
ratio
0.01
12
43
346
2784
1.52
6.32
5.2
3.5
0.00
0.00
estimate
-0.00
68
553
343
2761
1.51
6.21
5.2
3.5
0.00
0.00
estimate
-0.00
65
564
88
507
1.85
6.17
2.2
1.9
19.45
17.11
iu/l
0.24
66
389
27
95
2.92
6.00
4.3
4.4
0.50
0.33
e9/l
0.72
22
57
188
1339
1.57
5.96
4.2
3.5
—
0.00
—
0
6
29
107
2.79
5.92
7.0
5.7
90.58
90.86
%
0.07
29
101
93
553
1.79
5.88
1.3
1.2
—
—
—
0
0
17
35
4.95
5.77
2.4
2.5
1.19
1.51
g/24h
0.19
12
27
603
5582
2.08
5.76
24.9
13.0
28.35
21.27
mg/l
5.18
520
4293
20
60
3.40
5.75
1.6
1.3
—
—
—
0
0
345
2814
1.48
5.65
5.2
3.5
0.00
0.00
estimate
-0.00
63
524
107
680
1.68
5.35
4.9
5.4
8.18
6.66
umol/l
0.23
86
586
101
632
1.71
5.34
1.8
1.6
—
—
—
0
0
52
264
2.05
5.28
13.7
9.7
0.62
0.61
%
0.09
52
264
15
30
5.09
5.27
2.2
3.6
161.35
160.75
ug/l
0.00
15
30
87
524
1.76
5.27
2.8
2.6
32.46
32.14
u/l
0.04
82
438
16
35
4.66
5.20
2.0
2.0
18.00
16.30
nmol/l
—
7
10
59
316
1.95
5.16
4.2
4.2
7.37
7.34
ph
0.60
49
241
16
45
3.62
5.06
1.9
2.6
—
—
—
0
0
24
88
2.79
4.98
6.3
5.6
8.98
9.03
kpa
0.04
24
88
109
709
1.64
4.97
2.5
2.3
2.43
2.43
mmol/l
0.06
92
626
490
4343
1.52
4.91
5.2
4.2
14.87
14.46
pmol/l
2.97
467
4071
612
5742
2.09
4.89
19.9
10.5
—
—
—
0
0
44
218
2.09
4.78
1.5
1.3
—
—
—
0
0
32
140
2.35
4.68
2.1
2.0
—
—
—
0
0
32
140
2.35
4.68
2.1
2.0
—
—
—
0
0
32
140
2.35
4.68
2.1
2.0
—
—
—
0
0
32
140
2.35
4.68
2.1
2.0
—
—
—
0
0
17
53
3.26
4.63
1.5
4.2
—
—
—
0
0
192
1445
1.46
4.51
3.1
2.9
58.80
63.68
u/l
0.39
180
1364
67
394
1.78
4.41
2.5
2.0
6.02
7.39
u/l
0.73
42
280
547
5006
1.57
4.34
6.1
4.9
1.92
1.85
mu/l
0.95
529
4780
21
78
2.75
4.28
2.7
2.3
—
—
—
0
0
41
207
2.04
4.26
1.1
1.3
—
—
—
0
0
217
1692
1.42
4.16
3.8
2.8
—
0.12
—
0
17
158
1165
1.47
4.08
6.6
4.3
18.57
23.44
mg/mmol
0.13
122
773
26
550
0.45
4.04
1.7
1.6
1055.21
960.90
mu/l
0.16
26
472
148
1079
1.48
4.04
3.4
3.4
351.35
327.43
umol/l
1.92
139
999
28
124
2.31
4.01
6.0
5.1
7.40
7.41
ph
0.22
28
124
212
1656
1.41
4.00
6.3
4.0
7.32
8.62
mmol/l
3.83
195
1491
22
87
2.58
4.00
1.6
1.5
4320.20
16218.28
e6/l
1.01
15
58
29
584
0.47
3.94
1.6
1.6
3.41
3.40
mmol/l
0.01
19
400
51
286
1.85
3.93
7.1
5.1
1.22
1.23
mmol/l
0.25
46
255
22
88
2.55
3.91
6.5
5.6
5.10
4.94
kpa
0.70
22
88
22
88
2.55
3.91
6.5
5.6
1.99
2.39
mmol/l
0.46
15
51
557
5159
1.55
3.74
30.5
17.1
13.63
13.25
%
10.26
551
5116
24
104
2.36
3.63
1.5
1.3
5.63
3.92
u/ml
0.30
16
52
88
587
1.58
3.61
2.9
2.3
11.34
12.66
nmol/l
0.68
81
549
17
62
2.79
3.60
3.9
5.3
2.01
2.29
ug/l
0.16
17
62
12
30
4.05
3.60
3.2
8.3
4.68
4.83
kpa
0.38
12
30
12
30
4.05
3.60
3.2
8.3
6.27
6.13
kpa
0.27
12
30
22
92
2.44
3.59
19.1
19.3
10.94
11.83
%
0.73
22
92
106
741
1.51
3.53
1.5
1.6
427.01
50000441.39
pmol/l
1.29
88
672
29
139
2.14
3.48
1.3
1.8
0.65
0.76
g/l
0.24
24
116
15
52
2.93
3.48
1.3
1.2
99.47
116.33
pmol/l
0.69
15
52
13
42
3.14
3.38
7.2
2.8
—
—
—
0
0
8
14
5.77
3.34
3.6
3.9
13.75
6.57
%
—
8
14
45
256
1.81
3.34
1.4
1.2
—
—
—
0
0
152
1152
1.42
3.33
6.1
3.7
107.14
62.20
mg/l
1.09
125
788
9
19
4.78
3.24
1.1
1.1
—
—
—
0
0
85
577
1.54
3.24
4.4
3.4
10.09
9.65
g/l
0.44
75
542
32
582
0.53
3.22
1.2
2.0
—
—
—
0
0
21
91
2.35
3.20
3.8
4.0
3.34
3.98
e9/l
0.80
21
91
21
91
2.35
3.20
2.3
2.3
—
—
—
0
0
8
15
5.38
3.19
3.6
3.5
32.00
26.73
%
—
8
15
11
29
3.84
3.19
1.0
1.3
—
—
—
0
0
13
40
3.29
3.15
1.4
2.2
1.02
1.06
%
—
8
17
9
20
4.54
3.12
1.3
1.6
—
—
—
0
0
81
549
1.54
3.11
1.5
1.4
233.91
279.73
u/ml
0.16
73
511
35
188
1.91
3.11
8.5
7.4
—
—
—
0
0
20
86
2.37
3.10
1.4
1.3
—
—
—
0
0
19
80
2.41
3.08
4.4
3.9
1.57
1.72
umol/l
0.41
19
75
16
62
2.62
3.06
1.0
1.0
—
—
—
0
0
177
1399
1.36
2.99
5.4
3.5
0.00
0.00
estimate
0.50
63
533
230
1892
1.33
2.99
1.6
1.6
—
—
—
0
0
48
289
1.71
2.97
3.2
4.5
4.67
19.78
ug/l
0.49
31
228
596
5662
1.61
2.94
14.6
10.7
26.70
27.30
u/l
0.29
586
5546
10
27
3.74
2.88
4.7
2.8
262.20
173.59
e6/l
—
10
27
7
13
5.43
2.87
2.0
3.2
0.61
0.62
mmol/l
—
7
13
34
585
0.56
2.85
1.5
2.1
—
—
—
0
0
41
239
1.76
2.84
2.4
1.9
—
—
—
0
0
27
137
2.01
2.83
1.2
1.1
—
—
—
0
0
34
581
0.56
2.78
1.5
2.1
—
—
—
0
0
34
580
0.56
2.76
1.5
2.1
—
—
—
0
0
479
4391
1.34
2.75
5.9
4.9
36.14
37.49
mmol/mol
3.42
460
4226
13
48
2.74
2.72
1.2
1.5
—
—
nmol/l
—
0
0
40
235
1.75
2.71
2.6
1.9
168.50
111.18
au/ml
2.22
14
90
10
29
3.48
2.70
1.8
3.8
2204.90
1291.31
mg
—
10
29
46
720
0.61
2.69
1.1
1.3
—
—
—
0
0
16
67
2.42
2.64
1.2
1.6
—
—
—
0
0
246
2071
1.30
2.64
2.0
2.0
1.54
1.35
mmol/l
1.76
223
1859
14
316
0.43
2.63
1.5
1.5
64.58
60.81
ug/l
0.12
14
272
87
621
1.46
2.63
1.7
1.6
—
—
—
0
0
12
42
2.89
2.55
1.1
1.9
2.36
3.72
nmol/l
0.78
12
42
220
1832
1.30
2.55
2.1
1.9
—
—
—
0
0
24
122
2.00
2.53
1.1
1.1
—
—
—
0
0
55
360
1.58
2.49
1.4
1.6
—
—
—
0
0
33
548
0.58
2.45
1.5
2.2
—
—
—
0
0
16
329
0.47
2.37
1.2
1.4
150.83
251.11
miu/ml
—
7
165
8
22
3.67
2.37
1.1
1.6
—
—
—
0
0
7
17
4.15
2.36
1.9
2.9
103.00
95.24
g/l
—
7
17
177
2128
0.77
2.33
2.8
2.6
—
—
—
0
0
18
85
2.15
2.30
1.3
1.3
—
—
—
0
0
6
13
4.64
2.27
2.0
1.2
9.13
11.37
mmol/l
—
6
13
27
150
1.83
2.23
3.3
3.2
2.35
3.50
index
0.33
17
94
11
41
2.71
2.21
7.0
4.8
—
—
—
0
0
12
48
2.53
2.19
1.7
2.8
32.50
32.58
pg
0.02
12
48
11
42
2.64
2.15
3.6
3.4
682.27
686.02
u/ml
0.01
11
42
65
457
1.47
2.15
2.4
2.0
1.06
1.13
g/l
0.18
58
433
29
169
1.75
2.07
1.2
1.2
—
—
—
0
0
59
413
1.47
2.00
5.5
6.5
0.00
0.08
%
1.70
17
103
58
405
1.47
1.99
5.5
6.1
0.11
0.09
%
0.11
18
114
5
11
4.57
1.94
3.0
1.5
—
—
—
0
0
637
6227
2.03
1.91
36.4
19.8
4.50
4.61
e12/l
5.91
632
6074
88
1137
0.74
1.91
1.9
1.9
—
—
—
0
0
637
6230
2.01
1.86
36.5
19.9
6.78
6.73
e9/l
0.22
632
6072
27
160
1.72
1.84
1.4
1.4
354.58
305.30
ug/g
0.78
19
81
6
17
3.55
1.84
2.2
5.3
17.63
16.80
%
—
6
17
57
404
1.45
1.83
4.6
5.8
0.33
0.53
%
0.63
18
124
5
12
4.19
1.82
3.4
1.2
82.60
66.98
ng/l
—
5
12
19
101
1.91
1.82
1.3
1.3
—
—
—
0
0
30
184
1.66
1.81
2.2
2.2
3.25
4.37
iu/l
0.29
13
79
6
18
3.35
1.75
1.2
1.8
—
—
—
0
0
28
171
1.66
1.73
1.3
1.4
0.45
0.36
nmol/l
0.20
23
134
7
24
2.93
1.72
1.1
1.4
30.71
27.33
s
—
7
24
5
13
3.86
1.71
1.0
2.2
—
—
—
0
0
72
542
1.37
1.66
1.3
1.5
—
—
—
0
0
41
280
1.49
1.60
2.1
1.9
262.24
184.44
u/ml
0.69
25
144
31
468
0.64
1.60
1.6
2.2
—
—
—
0
0
8
32
2.52
1.60
2.6
3.4
—
—
—
0
0
11
50
2.22
1.57
1.5
1.7
—
—
—
0
0
15
268
0.55
1.51
1.9
2.7
—
—
—
0
0
28
178
1.60
1.50
2.3
1.6
—
—
—
0
0
6
21
2.87
1.50
1.0
1.2
—
—
—
0
0
58
430
1.38
1.49
5.6
6.0
1.26
0.66
%
0.51
19
140
5
16
3.14
1.44
1.0
1.1
—
—
—
0
0
6
23
2.62
1.37
1.2
3.5
—
—
—
0
0
6
23
2.62
1.37
3.0
2.8
—
—
—
0
0
5
17
2.95
1.36
1.2
1.4
—
—
—
0
0
0
41
0.00
1.31
0.0
1.2
—
—
—
0
0
9
43
2.11
1.30
1.6
3.4
2.33
2.77
nmol/l
—
9
43
9
43
2.11
1.30
1.2
1.3
—
—
—
0
0
8
35
2.30
1.27
1.3
1.1
—
—
—
0
0
6
25
2.41
1.24
4.7
3.0
512.67
532.07
min
—
6
14
51
386
1.35
1.19
1.8
1.5
366.50
322.26
mu/l
0.37
46
358
26
174
1.51
1.16
4.1
2.9
55.64
56.02
%
0.05
26
174
226
2029
1.17
1.14
5.2
3.1
0.00
0.00
estimate
0.50
56
475
42
311
1.37
1.13
1.1
1.2
—
—
—
0
0
5
21
2.39
1.09
3.0
2.0
1614.80
2153.10
ml
—
5
21
53
410
1.32
1.08
8.0
3.4
—
—
—
0
0
7
32
2.20
1.08
1.9
2.9
—
—
—
0
0
16
97
1.66
1.07
1.0
1.1
1.49
1.42
g/l
0.35
16
89
103
867
1.22
1.06
1.6
1.4
240.00
468.26
titre
1.89
16
167
30
414
0.71
1.04
5.6
2.8
—
—
—
0
0
173
1533
1.17
1.02
5.3
2.8
0.02
0.00
estimate
0.33
57
452
77
632
1.25
1.01
1.6
1.3
—
—
—
0
0
12
68
1.78
1.01
1.6
2.2
—
—
—
0
0
51
401
1.29
0.95
2.7
2.0
0.00
0.03
estimate
—
8
111
30
217
1.40
0.95
2.8
2.0
0.00
0.01
estimate
—
6
87
6
27
2.23
0.93
4.5
3.1
745.00
631.53
ml
—
6
15
28
201
1.41
0.92
2.3
2.4
—
—
—
0
0
6
29
2.08
0.89
1.0
1.4
—
—
—
0
0
48
379
1.29
0.88
2.5
2.0
6.26
6.28
ph
0.04
31
235
6
111
0.54
0.84
1.5
1.3
—
—
—
0
0
5
24
2.09
0.74
2.0
4.3
5.68
7.15
mmol/l
—
5
24
61
508
1.22
0.73
1.4
1.3
191.18
158.49
u/ml
0.14
15
191
9
55
1.64
0.73
4.2
3.9
0.67
0.73
index
—
9
55
10
60
1.68
0.72
1.1
1.1
—
—
—
0
0
7
40
1.76
0.71
1.3
1.2
777.14
174.32
iu/ml
—
7
40
475
4585
1.13
0.70
4.6
3.8
5.68
5.68
mmol/l
0.02
449
4312
28
213
1.33
0.69
1.3
1.2
—
—
—
0
0
195
1791
1.13
0.69
1.8
1.6
1.98
1.95
g/l
0.09
110
1054
10
61
1.65
0.68
1.5
1.6
—
—
—
0
0
5
27
1.86
0.68
1.0
1.0
—
—
—
0
0
28
214
1.32
0.67
1.3
1.2
—
—
—
0
0
7
43
1.63
0.67
1.0
1.1
—
—
—
0
0
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
5
28
1.79
0.66
1.8
1.1
—
—
—
0
0
148
1340
1.13
0.66
5.5
5.2
—
—
—
0
0
7
44
1.60
0.65
1.0
1.0
—
—
—
0
0
24
181
1.34
0.63
1.2
1.2
—
—
—
0
0
57
482
1.20
0.61
1.9
1.7
—
—
—
0
0
8
51
1.57
0.60
1.0
1.0
—
—
—
0
0
498
4837
1.12
0.60
5.0
4.2
4.47
4.62
mmol/l
3.42
479
4654
26
331
0.78
0.59
1.2
1.1
—
—
—
0
0
10
64
1.57
0.58
1.1
1.1
—
—
—
0
0
467
4523
1.11
0.58
4.3
3.6
1.33
1.23
mmol/l
1.68
448
4306
79
897
0.86
0.58
1.6
1.3
12.52
6.48
u/ml
0.31
31
334
6
35
1.72
0.57
4.2
2.7
4.03
4.01
mmol/l
—
6
35
6
35
1.72
0.57
4.2
2.7
101.50
105.29
mmol/l
—
6
35
6
35
1.72
0.57
4.2
2.7
1.21
1.20
mmol/l
—
6
35
8
54
1.49
0.57
1.3
2.0
—
—
—
0
0
52
608
0.84
0.55
1.6
1.8
—
—
—
0
0
498
4852
1.11
0.51
5.3
4.5
2.72
2.78
mmol/l
0.82
481
4646
10
67
1.50
0.49
1.0
1.2
—
—
—
0
0
88
787
1.14
0.49
1.2
1.3
—
—
—
0
0
493
4806
1.10
0.48
4.9
4.1
1.32
1.43
mmol/l
9.20
474
4598
7
110
0.63
0.48
1.0
1.1
—
—
—
0
0
137
1260
1.11
0.48
4.8
3.3
1.02
1.02
kg/l
0.83
101
808
8
118
0.67
0.46
1.0
1.1
—
—
—
0
0
69
612
1.14
0.44
1.6
1.4
—
—
—
0
0
10
69
1.46
0.44
1.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
264.78
—
0
9
23
186
1.24
0.40
2.0
1.8
194.43
228.17
pmol/l
0.63
23
179
28
335
0.83
0.40
1.7
1.6
—
—
—
0
0
31
367
0.84
0.40
1.1
1.2
2.81
3.07
u/ml
0.07
21
247
14
106
1.33
0.39
1.1
1.9
—
—
—
0
0
167
1771
0.92
0.38
2.4
2.2
—
—
—
0
0
51
450
1.14
0.37
3.1
2.4
10586.67
6011.75
u/l
0.27
16
179
5
37
1.35
0.37
2.0
2.8
36.00
42.43
%
—
5
37
5
37
1.35
0.37
4.0
5.7
20.20
8.14
%
—
5
37
9
71
1.27
0.36
1.2
1.3
242.33
493.62
pmol/l
—
9
66
9
71
1.27
0.36
6.8
3.3
—
—
—
0
0
6
44
1.37
0.34
1.5
1.1
—
—
—
0
0
6
44
1.37
0.34
1.0
1.1
—
—
—
0
0
72
655
1.11
0.33
4.8
3.2
4.17
5.28
e9/l
0.99
66
598
105
975
1.09
0.33
2.3
1.7
—
—
—
0
0
13
165
0.78
0.32
1.2
1.2
—
—
—
0
0
7
53
1.32
0.31
1.0
1.1
—
—
—
0
0
31
356
0.86
0.30
1.7
1.8
—
—
—
0
0
8
62
1.29
0.28
1.3
1.1
—
—
—
0
0
33
374
0.88
0.27
1.3
1.2
—
—
—
0
0
29
253
1.15
0.26
2.2
1.8
40.41
37.61
nmol/l
0.17
29
245
135
1420
0.94
0.26
2.2
1.8
—
—
—
0
0
9
74
1.22
0.25
1.2
1.3
25.99
184.05
mu/l
—
9
69
21
244
0.86
0.24
1.1
1.1
3.23
4.61
u/ml
0.32
14
149
103
970
1.07
0.24
3.5
4.0
1.45
1.49
ug/l
0.08
97
882
14
115
1.22
0.23
1.7
1.4
12.23
18.57
u/l
—
9
97
203
1961
1.05
0.21
1.6
1.7
1.71
2.43
u/ml
0.27
53
468
0
10
0.00
0.21
0.0
1.0
—
4.48
—
0
10
0
12
0.00
0.21
0.0
1.2
—
0.60
—
0
7
29
324
0.89
0.21
2.4
1.7
0.19
0.28
mg/l
—
9
141
0
13
0.00
0.21
0.0
1.0
—
0.11
—
0
7
0
13
0.00
0.21
0.0
2.8
—
2.77
—
0
13
30
333
0.90
0.20
1.1
1.2
2.26
6.60
u/ml
2.21
23
234
13
154
0.84
0.19
12.5
9.4
—
—
—
0
0
27
241
1.12
0.19
1.5
1.3
—
—
—
0
0
34
311
1.10
0.16
1.0
1.1
—
—
—
0
0
116
1115
1.05
0.15
2.9
3.3
96.69
95.47
ug/g
0.03
98
914
10
119
0.84
0.15
1.0
1.0
—
—
—
0
0
14
160
0.87
0.14
1.1
4.2
—
—
—
0
0
8
99
0.81
0.13
1.1
4.2
—
—
—
0
0
30
325
0.92
0.13
1.1
1.2
1.18
1.05
u/ml
0.04
19
209
17
152
1.12
0.12
1.5
1.2
—
—
—
0
0
30
322
0.93
0.11
1.1
1.2
3.54
1.99
u/ml
0.35
21
217
55
577
0.95
0.11
2.2
2.7
0.67
0.67
ug/l
0.01
35
296
10
86
1.16
0.11
2.6
4.6
—
—
—
0
0
21
228
0.92
0.10
1.1
1.1
4.57
8.24
u/ml
0.64
15
130
5
46
1.09
0.09
3.2
1.7
—
—
—
0
0
95
977
0.97
0.09
1.5
1.3
53.27
24.98
iu/ml
0.34
24
269
21
222
0.94
0.05
1.0
1.1
2.42
0.33
u/ml
0.43
11
99
10
110
0.91
0.05
1.1
5.4
—
—
—
0
0
21
221
0.95
0.04
1.8
1.7
23.60
5.17
u/ml
—
5
68
16
170
0.94
0.04
1.1
3.8
3.51
3.42
mmol/l
0.32
16
162
16
169
0.94
0.03
1.1
4.1
3.27
15.14
e6/l
1.15
11
117
382
3801
1.01
0.03
4.3
3.9
54.91
38.28
u/l
1.54
367
3686
19
184
1.03
0.00
1.1
3.8
312.26
442.49
mg/l
1.97
19
177
26
260
1.00
0.00
1.0
1.1
1.43
1.50
g/l
1.04
26
260
11
108
1.02
0.00
6.3
3.5
72.04
5.07
u/ml
0.45
11
108
11
110
1.00
0.00
1.1
1.2
—
—
—
0
0
26
265
0.98
0.00
1.0
1.1
0.90
0.90
g/l
0.03
26
265
12
123
0.97
0.00
1.5
1.3
41.94
184.10
pmol/l
0.91
12
118
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
6.12
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
0.20
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
-0.00
3.5
4.9
16.83
494.71
u/ml
—
6
54
0
7
0.00
-0.00
0.0
1.4
—
1.69
—
0
7
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.4
—
—
—
0
0
7
76
0.92
-0.00
1.0
1.3
—
353.00
—
0
10
0
8
0.00
-0.00
0.0
1.0
—
5.45
—
0
8
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
—
—
0
0
5
49
1.02
-0.00
4.4
2.3
38.00
35.97
mg/l
—
5
37
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS and mortality.

Females

Parameter HR [95% CI] p-value
Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS 4.369 [3.04, 6.28] < 0.001
Birth year 0.994 [0.99, 1.0] 0.176

During the follow-up period (1.1.1998 — 31.12.2019), 139 out of 2512 females with Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS died.

Males

Parameter HR [95% CI] p-value
Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS 4.099 [3.26, 5.16] < 0.001
Birth year 0.987 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 192 out of 2556 males with Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS died.

Mortality risk

Mortality risk for people of age

years, who have Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS.

N-year risk Females Males
1 0.44% 0.835%
5 2.571% 4.97%
10 6.367% 12.307%
15 11.887% 21.957%
20 20.333% 34.286%

Relationships between endpoints

Index endpoint: Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS – Other specified congenital malformation syndromes affecting multiple systems

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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