No definition available.
Congenital nasolacrimal duct obstruction or stenosis
Q17_CONGENITAL_NASOLACRIMAL_DUCT_OBSTRUCTION_OR_STENOSIS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
192 |
4. Check minimum number of eventsNone |
192 |
5. Include endpointsNone |
192 |
6. Filter based on genotype QC (FinnGen only) |
173 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Congenital nasolacrimal duct obstruction or stenosis
based on the number of shared cases.
Similar with more cases:
- Congenital nasolacrimal duct obstruction or stenosis, including avohilmo
- Congenital malformations of eyelid, lacrimal apparatus and orbit
- Congenital malformations of eyelid, lacrimal apparatus and orbit, including avohilmo
- Congenital malformations of eye, ear, face and neck
- Congenital malformations, deformations and chromosomal abnormalities
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 173 | 117 | 56 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.03 |
| Median age at first event (years) | 1.28 | 1.31 | 1.21 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 181
- Matched controls
- 1809
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q10.5
ICD-10 Finland
Congenital stenosis and stricture of lacrimal duct
+∞
257.6
181
*
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
927.8
102.3
91
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
53.8
29.9
35
8
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
344.0
29.7
29
*
ZXD10
NOMESCO Finland
Scheduled procedure
3.1
12.1
78
357
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
116.4
10.5
11
*
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
105.2
9.5
10
*
ZXE00
NOMESCO Finland
One hour or less
2.4
7.5
79
441
ZXA10
NOMESCO Finland
Bilateral
2.8
7.2
43
182
ZXA00
NOMESCO Finland
Right side
2.9
6.0
30
115
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
66
474
1.62
2.39
5.3
4.5
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
11
4.64
1.95
1.6
1.0
120.80
120.27
%
—
5
11
56
409
1.53
1.82
4.5
4.4
0.08
0.32
e6/l
1.71
46
287
7
27
2.65
1.53
1.6
1.1
—
—
—
0
0
24
149
1.70
1.50
1.3
1.4
144.85
374.24
u/ml
0.73
19
142
57
436
1.45
1.45
6.7
7.8
38.77
37.42
g/l
1.11
57
415
32
221
1.54
1.33
1.5
1.5
—
—
—
0
0
10
48
2.15
1.30
7.7
25.3
0.63
0.67
%
—
10
48
10
48
2.15
1.30
8.0
25.2
21.80
23.93
mmol/l
—
10
48
8
36
2.28
1.26
1.4
1.7
—
—
—
0
0
33
234
1.50
1.22
2.7
2.4
3807.03
6134.66
u/l
—
10
76
21
134
1.64
1.20
8.6
14.8
104.81
105.81
mmol/l
0.38
21
134
10
50
2.06
1.18
7.8
24.4
1.05
1.13
%
—
10
50
8
41
1.99
1.10
15.5
4.8
59.33
53.26
%
—
8
41
37
276
1.43
1.07
3.0
2.6
21.44
13.64
ng/l
0.25
18
113
32
233
1.45
1.05
8.0
10.9
1.50
0.89
mmol/l
0.49
27
182
79
669
1.32
1.04
1.7
1.7
1.40
2.42
u/ml
0.40
17
136
12
70
1.76
0.95
1.0
1.1
0.07
0.42
u/ml
—
5
31
160
1512
1.50
0.94
12.3
11.8
22.37
21.52
mg/l
0.10
127
1130
52
421
1.33
0.92
3.0
2.5
—
—
—
0
0
12
71
1.74
0.91
3.1
3.5
1.21
1.24
mmol/l
1.28
12
60
67
564
1.30
0.90
3.0
3.5
—
—
estimate
—
0
0
35
269
1.37
0.86
2.7
4.3
1.03
1.40
mg/l
0.38
21
184
46
373
1.31
0.80
2.7
2.3
—
—
—
0
0
17
115
1.53
0.80
1.2
1.2
0.10
3.55
u/ml
2.26
11
76
34
264
1.35
0.79
4.8
4.3
1.10
1.26
e6/l
0.14
22
138
65
554
1.27
0.78
6.4
7.2
19.12
20.65
umol/l
0.10
59
517
6
34
1.79
0.77
1.2
2.0
—
—
—
0
0
72
625
1.25
0.73
11.9
11.2
1.22
1.23
mmol/l
0.40
67
567
5
26
1.95
0.71
1.0
1.0
—
—
—
0
0
7
41
1.73
0.70
4.6
3.9
96.14
483.89
ug/l
—
7
35
31
244
1.33
0.67
15.5
18.1
24.99
24.60
mmol/l
0.44
31
244
13
188
0.67
0.67
6.5
4.2
304.54
291.25
umol/l
0.14
13
174
5
28
1.81
0.66
1.2
1.5
—
—
—
0
0
5
28
1.81
0.66
1.2
1.4
—
—
—
0
0
116
1073
1.22
0.62
8.1
8.4
106.07
108.28
ml/min/173m2
0.50
95
881
0
20
0.00
0.60
0.0
3.9
—
—
—
0
0
0
20
0.00
0.60
0.0
3.9
—
—
—
0
0
84
754
1.21
0.60
6.7
7.5
5.81
5.95
mmol/l
0.34
79
683
174
1696
1.66
0.60
19.6
18.2
66.41
40.10
%
0.50
174
1679
174
1695
1.67
0.60
19.1
17.0
87.20
87.52
fl
0.37
174
1679
10
64
1.59
0.60
1.1
1.4
—
—
—
0
0
13
89
1.50
0.59
8.2
3.6
—
—
—
0
0
8
53
1.53
0.59
1.4
1.1
—
—
—
0
0
154
1472
1.31
0.59
3.9
4.0
—
—
—
0
0
5
89
0.55
0.57
1.4
1.3
—
—
—
0
0
19
142
1.38
0.57
2.0
2.1
—
—
—
0
0
111
1029
1.20
0.55
3.0
3.1
1.41
1.42
mmol/l
0.04
106
984
27
215
1.30
0.55
6.1
10.9
23.33
23.28
mmol/l
0.03
27
215
9
61
1.50
0.54
11.0
16.7
0.81
0.67
%
—
9
61
36
301
1.24
0.50
3.0
3.4
—
—
—
0
0
174
1699
1.61
0.50
19.7
17.4
134.67
134.59
g/l
0.03
174
1681
56
630
0.84
0.48
3.0
2.6
—
—
—
0
0
31
257
1.25
0.47
5.0
4.5
5.55
3.54
e6/l
0.27
19
134
30
248
1.25
0.46
11.1
11.4
1.31
1.31
mmol/l
0.04
30
234
12
86
1.42
0.45
3.3
2.5
0.07
0.15
e6/l
0.74
12
79
7
50
1.41
0.45
1.6
1.9
—
—
—
0
0
101
940
1.17
0.44
9.0
9.8
3.64
3.74
e9/l
0.15
88
785
100
931
1.16
0.43
2.8
2.8
1.02
1.10
mmol/l
0.92
95
894
127
1205
1.18
0.43
4.0
3.7
14.50
14.53
pmol/l
0.05
113
1071
5
32
1.58
0.42
5.6
4.3
92.20
98.16
%
—
5
32
5
33
1.53
0.41
2.2
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
80.17
—
0
18
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
24
198
1.24
0.38
14.3
10.6
9.23
9.43
kpa
0.21
24
192
18
143
1.29
0.38
2.0
2.1
—
—
—
0
0
5
36
1.40
0.38
1.0
1.4
—
—
—
0
0
5
36
1.40
0.38
1.0
1.4
—
—
—
0
0
22
180
1.25
0.38
1.4
1.3
—
—
—
0
0
6
41
1.48
0.36
1.2
1.5
—
—
—
0
0
6
44
1.38
0.35
4.0
12.0
—
95.20
—
0
5
60
656
0.87
0.34
3.1
2.8
—
—
—
0
0
10
74
1.37
0.33
1.3
1.5
—
—
—
0
0
11
83
1.35
0.32
2.1
1.9
—
—
—
0
0
12
92
1.33
0.32
5.3
14.0
97.42
89.04
%
0.86
12
92
104
986
1.13
0.31
4.2
4.2
6.17
7.88
mm/h
2.11
96
920
24
204
1.20
0.30
1.0
1.1
—
—
—
0
0
7
55
1.28
0.30
1.9
2.1
—
—
—
0
0
12
94
1.30
0.29
2.1
1.9
—
—
—
0
0
44
399
1.13
0.26
4.7
2.7
1.01
1.02
kg/l
1.47
29
234
26
227
1.17
0.25
13.7
10.1
5.22
5.10
kpa
0.39
26
222
17
201
0.83
0.25
1.1
1.2
1.54
5.01
u/ml
—
5
70
32
285
1.15
0.24
1.8
1.4
15.98
20.81
nmol/l
1.71
26
252
16
189
0.83
0.23
1.8
1.6
1147.58
931.45
mu/l
0.59
16
178
7
92
0.75
0.23
3.0
1.7
—
—
—
0
0
5
40
1.26
0.22
1.0
1.8
—
—
—
0
0
25
220
1.16
0.22
14.2
10.2
1.73
0.91
mmol/l
0.65
19
160
10
124
0.79
0.22
1.4
1.4
—
—
—
0
0
45
414
1.11
0.21
2.2
1.7
94.81
93.74
pmol/l
0.06
27
209
0
10
0.00
0.21
0.0
1.2
—
115.85
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
281.33
—
0
12
17
197
0.85
0.21
2.1
4.1
264.50
389.98
ng/l
—
8
105
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
76.29
—
0
14
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
80
764
1.08
0.18
5.0
3.6
0.00
0.00
estimate
-0.00
15
160
7
61
1.15
0.18
6.4
4.5
21.86
26.83
nmol/l
—
7
61
6
79
0.75
0.16
1.5
1.7
—
—
—
0
0
9
80
1.13
0.15
6.9
7.3
167.22
177.58
%
—
9
80
9
81
1.12
0.15
2.0
1.8
—
—
—
0
0
8
98
0.81
0.14
1.4
1.4
—
—
—
0
0
11
94
1.18
0.13
2.5
1.7
—
—
—
0
0
22
200
1.11
0.13
2.1
2.0
—
—
—
0
0
110
1074
1.06
0.11
3.2
2.9
5.25
5.39
mmol/l
1.23
97
982
19
173
1.11
0.11
5.7
5.9
8.70
9.64
umol/l
0.09
14
146
12
135
0.88
0.10
1.5
2.6
24.92
30.36
u/l
1.02
12
112
79
766
1.05
0.10
5.2
3.6
0.00
0.00
estimate
-0.00
14
160
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
5
46
1.09
0.09
1.0
1.2
—
—
—
0
0
5
46
1.09
0.09
1.2
1.5
—
—
—
0
0
78
757
1.05
0.09
5.1
3.6
0.00
0.00
estimate
-0.00
15
166
24
257
0.92
0.09
1.3
1.5
1.25
1.37
%
1.02
24
231
6
56
1.07
0.09
1.0
1.1
1.45
1.52
g/l
—
6
56
6
56
1.07
0.09
1.0
1.1
0.85
0.77
g/l
—
6
56
7
65
1.08
0.08
1.1
1.1
—
14.40
—
0
7
6
70
0.85
0.08
1.3
1.3
1.12
1.16
g/l
—
6
65
6
72
0.83
0.08
1.0
1.1
—
17.46
—
0
14
7
81
0.86
0.07
2.4
1.5
41.64
55.96
ug/l
—
7
81
9
87
1.04
0.07
2.0
2.4
—
—
—
0
0
40
384
1.05
0.07
4.0
2.5
2.38
2.39
mmol/l
0.28
40
354
15
138
1.09
0.06
1.4
1.4
220.12
269.76
miu/ml
—
10
74
21
197
1.07
0.06
12.4
10.3
0.80
0.80
mmol/l
0.17
21
186
136
1347
1.04
0.04
4.9
4.4
1.95
1.93
mu/l
0.07
127
1274
15
159
0.94
0.03
1.3
1.3
3.45
3.29
ratio
—
10
95
57
559
1.03
0.03
4.7
3.0
0.00
0.01
estimate
0.80
12
136
76
770
0.98
0.03
2.0
2.0
—
—
—
0
0
17
178
0.95
0.02
2.0
2.6
331.59
387.49
nmol/l
0.73
17
171
10
107
0.93
0.02
1.3
2.1
—
—
—
0
0
43
437
0.98
0.01
3.0
2.8
0.00
0.01
estimate
0.50
12
135
10
94
1.07
0.00
1.2
1.2
—
7.01
—
0
7
39
395
0.98
0.00
5.3
3.5
0.00
0.00
estimate
-0.00
16
156
0
6
0.00
0.00
0.0
1.2
—
1.60
—
0
6
0
6
0.00
0.00
0.0
1.2
—
55.17
—
0
6
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
12.77
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
20.83
—
0
6
0
6
0.00
0.00
0.0
5.3
—
178.50
—
0
6
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
19.45
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
13.29
—
0
7
5
50
1.00
-0.00
1.0
1.2
—
2.14
—
0
5
0
8
0.00
-0.00
0.0
1.3
—
2.50
—
0
8
9
89
1.01
-0.00
3.2
2.9
4.36
5.13
pmol/l
—
9
81
6
66
0.91
-0.00
1.0
1.0
7.37
7.51
kpa
—
6
57
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
8
89
0.89
-0.00
1.3
1.5
46.04
64.15
ug/l
—
8
80
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
10.96
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
122.71
—
0
7
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
4.00
—
0
5
6
66
0.91
-0.00
1.0
1.0
19.83
18.94
mmol/l
—
6
66
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
65
0.92
-0.00
1.0
1.0
2.68
3.29
kpa
—
6
56
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_CONGENITAL_NASOLACRIMAL_DUCT_OBSTRUCTION_OR_STENOSIS – Congenital nasolacrimal duct obstruction or stenosis
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).