No definition available.
Congenital nasolacrimal duct obstruction or stenosis, including avohilmo
Q17_CONGENITAL_NASOLACRIMAL_DUCT_OBSTRUCTION_OR_STENOSIS_WIDE
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
213 |
4. Check minimum number of eventsNone |
213 |
5. Include endpointsNone |
213 |
6. Filter based on genotype QC (FinnGen only) |
190 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF13
Similar endpoints
↥List of similar endpoints to
Congenital nasolacrimal duct obstruction or stenosis, including avohilmo
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of eyelid, lacrimal apparatus and orbit, including avohilmo
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 190 | 129 | 61 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.03 |
| Median age at first event (years) | 1.30 | 1.35 | 1.19 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 202
- Matched controls
- 2019
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q10.5
ICD-10 Finland
Congenital stenosis and stricture of lacrimal duct
+∞
292.4
202
*
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
409.7
98.1
91
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
54.0
36.7
43
10
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
337.8
29.6
29
*
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
149.6
13.6
14
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.8
11.1
87
433
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
63.4
10.7
12
*
ZXE00
NOMESCO Finland
One hour or less
2.4
8.6
93
526
ZXA10
NOMESCO Finland
Bilateral
2.6
6.6
46
209
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
76
561
1.57
2.38
5.0
4.5
—
—
—
0
0
66
489
1.52
1.98
4.2
4.4
0.12
0.33
e6/l
1.53
53
357
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
14
3.63
1.62
1.6
1.0
120.80
119.36
%
—
5
14
5
15
3.39
1.53
1.0
1.0
—
—
—
0
0
5
16
3.17
1.44
1.0
1.0
—
—
—
0
0
26
174
1.57
1.23
1.3
1.4
137.81
352.14
u/ml
0.78
20
163
34
244
1.47
1.17
2.6
2.5
3461.05
5746.22
u/l
0.25
11
82
88
743
1.33
1.16
1.6
1.7
1.40
2.71
u/ml
0.55
17
153
11
58
1.95
1.14
8.2
27.6
0.65
0.67
%
0.10
11
58
7
30
2.38
1.13
1.6
1.1
—
—
—
0
0
11
59
1.91
1.09
8.3
27.3
1.06
1.06
%
0.00
11
59
11
60
1.88
1.05
8.5
26.6
22.00
24.04
mmol/l
0.55
11
60
64
523
1.33
1.04
6.5
7.9
38.74
37.22
g/l
1.48
64
497
23
158
1.51
0.99
8.1
14.0
104.96
105.41
mmol/l
0.16
23
158
34
254
1.41
0.96
1.5
1.5
—
—
—
0
0
36
272
1.39
0.96
6.9
10.5
4.60
5.12
kpa
1.55
36
265
111
986
1.28
0.95
4.0
3.6
48.92
49.50
ug/l
0.04
105
936
37
282
1.38
0.94
7.5
10.6
1.24
0.86
mmol/l
0.32
32
223
128
1164
1.27
0.87
3.2
3.5
2.56
2.60
mmol/l
0.18
121
1114
39
304
1.35
0.87
3.0
4.4
0.99
1.48
mg/l
0.63
25
213
37
286
1.36
0.87
7.4
10.5
5.94
5.74
kpa
0.82
37
279
6
31
1.96
0.85
1.0
1.0
—
—
—
0
0
179
1706
1.43
0.84
12.3
12.6
21.77
21.90
mg/l
0.01
142
1277
53
437
1.29
0.80
3.2
2.5
—
—
—
0
0
76
659
1.24
0.76
2.9
3.6
—
—
estimate
—
0
0
47
385
1.29
0.75
2.9
2.3
—
—
—
0
0
98
877
1.23
0.72
6.4
7.7
5.78
5.95
mmol/l
0.50
91
798
39
314
1.30
0.71
4.5
4.1
1.01
1.10
e6/l
0.09
24
166
195
1902
1.71
0.70
19.8
19.4
63.42
39.93
%
0.50
195
1883
195
1901
1.73
0.70
19.3
18.1
87.36
87.50
fl
0.15
195
1883
83
734
1.22
0.68
11.2
11.4
1.22
1.23
mmol/l
0.60
78
666
117
1075
1.21
0.64
9.2
10.5
3.66
3.69
e9/l
0.05
102
898
6
105
0.56
0.63
1.3
1.3
—
—
—
0
0
39
319
1.28
0.63
2.9
2.7
20.68
28.85
ng/l
0.21
19
139
110
1006
1.20
0.62
6.3
6.5
99.40
98.99
u/l
0.02
105
949
8
51
1.59
0.61
1.4
1.7
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
81.95
—
0
21
195
1905
1.67
0.60
19.8
18.5
134.10
133.93
g/l
0.06
195
1885
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
127
1181
1.20
0.59
8.3
9.2
104.48
106.49
ml/min/173m2
0.46
105
974
19
141
1.38
0.59
8.9
19.5
1.35
1.31
mmol/l
0.06
19
136
0
23
0.00
0.58
0.0
3.6
—
—
—
0
0
0
23
0.00
0.58
0.0
3.6
—
—
—
0
0
73
648
1.20
0.56
6.5
7.7
21.24
20.84
umol/l
0.02
67
602
126
1175
1.19
0.55
3.1
3.4
4.30
4.37
mmol/l
0.36
119
1132
170
1632
1.26
0.54
3.8
4.0
—
—
—
0
0
124
1157
1.18
0.53
3.0
3.3
1.44
1.43
mmol/l
0.09
116
1108
11
75
1.49
0.51
1.1
1.4
—
—
—
0
0
14
101
1.41
0.51
2.0
1.9
—
—
—
0
0
42
357
1.22
0.50
2.8
3.4
—
—
—
0
0
7
45
1.57
0.49
4.6
3.9
96.14
479.97
ug/l
—
7
39
15
111
1.38
0.48
5.8
13.3
95.67
88.27
%
0.54
15
111
12
86
1.42
0.45
3.1
4.1
1.21
1.23
mmol/l
1.14
12
74
7
50
1.41
0.45
3.6
13.4
—
176.83
—
0
6
36
305
1.22
0.45
4.5
4.2
5.02
3.03
e6/l
0.31
21
160
12
87
1.40
0.43
1.0
1.1
0.07
0.32
u/ml
—
5
42
8
57
1.42
0.42
1.0
1.1
1.52
1.52
g/l
—
8
57
8
57
1.42
0.42
1.0
1.1
0.81
0.77
g/l
—
8
57
8
58
1.39
0.42
1.4
1.1
—
—
—
0
0
35
298
1.21
0.42
14.6
17.8
24.99
24.51
mmol/l
0.66
35
298
5
33
1.53
0.41
1.2
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
5
34
1.48
0.40
1.2
1.4
—
—
—
0
0
119
1121
1.15
0.40
4.2
4.3
6.36
8.10
mm/h
2.47
110
1048
141
1345
1.16
0.40
3.9
3.8
14.51
14.53
pmol/l
0.03
124
1205
5
36
1.40
0.38
5.6
4.0
92.20
97.28
%
—
5
36
13
98
1.35
0.38
8.2
3.7
—
—
—
0
0
23
189
1.24
0.38
1.4
1.3
—
—
—
0
0
21
171
1.25
0.37
2.0
2.1
—
—
—
0
0
17
211
0.79
0.37
2.0
2.8
331.59
374.04
nmol/l
0.51
17
203
13
99
1.33
0.36
3.2
3.2
0.06
0.14
e6/l
0.87
13
92
13
99
1.33
0.36
1.9
1.9
—
—
—
0
0
27
229
1.21
0.34
1.0
1.1
—
—
—
0
0
6
45
1.34
0.34
1.2
2.0
—
—
—
0
0
49
439
1.15
0.33
4.3
3.0
1.01
1.02
kg/l
1.18
32
259
18
146
1.25
0.33
1.5
1.4
239.93
272.44
miu/ml
0.16
11
78
111
1051
1.12
0.32
2.7
3.0
1.02
1.11
mmol/l
1.12
103
1010
13
103
1.28
0.29
2.4
1.7
—
—
—
0
0
12
94
1.29
0.28
6.9
7.3
163.58
178.26
%
0.31
12
94
17
140
1.23
0.28
1.2
1.2
0.10
3.91
u/ml
2.41
11
95
44
485
0.88
0.27
2.1
2.0
1.24
1.21
mmol/l
0.09
39
442
34
301
1.16
0.27
10.5
11.6
1.31
1.31
mmol/l
0.01
34
285
9
73
1.24
0.26
11.0
15.0
0.81
0.65
%
—
9
73
7
92
0.75
0.23
1.4
1.7
—
—
—
0
0
11
88
1.26
0.23
1.3
1.6
—
—
—
0
0
5
41
1.22
0.22
1.0
1.8
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
20
173
1.17
0.21
2.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
16.96
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
143.62
—
0
12
0
13
0.00
0.21
0.0
1.1
—
293.92
—
0
13
0
13
0.00
0.21
0.0
2.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
76.29
—
0
14
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
1.2
1.2
—
—
—
0
0
6
50
1.21
0.20
1.0
1.5
—
—
—
0
0
6
50
1.21
0.20
1.0
1.5
—
—
—
0
0
61
648
0.92
0.20
3.0
2.5
—
—
—
0
0
6
51
1.18
0.19
1.2
1.3
—
—
—
0
0
6
51
1.18
0.19
1.2
1.5
—
—
—
0
0
6
51
1.18
0.19
1.2
1.4
—
—
—
0
0
6
51
1.18
0.19
1.2
1.6
0.15
0.25
nmol/l
—
6
40
90
861
1.08
0.18
4.7
3.7
0.00
0.00
estimate
-0.00
18
180
20
226
0.87
0.18
2.1
4.3
503.10
509.81
ng/l
—
10
124
12
101
1.20
0.17
2.0
2.8
—
—
—
0
0
6
79
0.75
0.16
1.3
1.3
1.12
1.16
g/l
—
6
74
50
470
1.08
0.15
2.2
1.7
94.81
94.19
pmol/l
0.03
27
232
35
324
1.10
0.15
1.7
1.5
16.53
21.26
nmol/l
1.71
29
284
27
247
1.11
0.14
13.1
11.7
9.39
9.51
kpa
0.11
27
241
82
850
0.94
0.13
2.0
2.0
—
—
—
0
0
9
108
0.83
0.13
1.3
1.4
—
—
—
0
0
25
230
1.10
0.12
2.1
2.0
—
—
—
0
0
65
676
0.94
0.12
3.0
2.7
—
—
—
0
0
88
853
1.06
0.11
4.8
3.7
0.00
0.00
estimate
-0.00
18
186
89
864
1.05
0.10
4.9
3.7
0.00
0.00
estimate
-0.00
17
178
5
44
1.14
0.10
2.2
1.9
—
—
—
0
0
12
106
1.14
0.10
1.2
1.3
—
7.01
—
0
7
123
1207
1.05
0.09
3.2
3.0
5.25
5.44
mmol/l
1.90
107
1108
6
56
1.07
0.08
1.0
1.2
—
2.14
—
0
5
10
113
0.88
0.08
1.3
2.1
—
—
—
0
0
7
65
1.08
0.08
1.6
1.9
—
—
—
0
0
12
133
0.90
0.08
1.4
1.4
—
—
—
0
0
8
77
1.04
0.07
1.0
1.1
—
17.46
—
0
14
64
621
1.04
0.07
4.4
3.2
0.00
0.01
estimate
0.80
15
154
9
86
1.05
0.07
2.2
1.5
42.65
56.70
ug/l
—
9
86
9
87
1.04
0.07
2.0
1.8
—
—
—
0
0
43
446
0.95
0.06
5.0
3.7
0.00
0.00
estimate
-0.00
19
175
19
203
0.93
0.06
1.7
1.6
1226.25
930.72
mu/l
0.95
19
189
9
103
0.87
0.06
3.2
3.2
4.36
5.03
pmol/l
—
9
93
29
280
1.04
0.03
12.6
11.1
5.21
5.05
kpa
0.64
29
275
10
108
0.92
0.03
2.6
1.8
—
—
—
0
0
45
440
1.03
0.02
3.7
2.7
2.38
2.39
mmol/l
0.31
45
407
28
272
1.03
0.02
13.0
11.1
1.60
0.89
mmol/l
0.63
22
197
15
156
0.96
0.01
1.6
2.7
54.87
33.19
u/l
0.33
15
130
48
481
1.00
0.00
2.9
3.0
0.00
0.01
estimate
0.50
15
153
17
171
0.99
0.00
1.2
1.3
3.31
3.28
ratio
0.03
12
106
151
1505
1.01
0.00
4.8
4.5
1.96
1.95
mu/l
0.03
141
1423
24
237
1.01
0.00
11.5
10.9
0.80
0.80
mmol/l
0.02
24
225
23
232
0.99
0.00
1.2
1.3
1.48
4.34
u/ml
—
6
84
21
210
1.00
0.00
5.6
5.8
8.13
9.14
umol/l
0.11
16
177
0
7
0.00
0.00
0.0
1.6
—
11.80
—
0
7
0
7
0.00
0.00
0.0
5.4
—
197.29
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
20.83
—
0
6
7
69
1.01
-0.00
1.1
1.1
—
12.66
—
0
8
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
8
80
1.00
-0.00
1.4
1.4
—
—
—
0
0
7
76
0.92
-0.00
1.0
1.0
7.11
7.52
kpa
—
7
64
0
6
0.00
-0.00
0.0
1.2
—
55.17
—
0
6
7
76
0.92
-0.00
1.0
1.0
19.43
19.17
mmol/l
—
7
76
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
39.17
—
0
6
9
99
0.90
-0.00
1.3
1.5
45.97
63.61
ug/l
—
9
87
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
6.33
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
7
75
0.93
-0.00
1.0
1.0
2.91
3.20
kpa
—
7
63
0
6
0.00
-0.00
0.0
1.2
—
1.60
—
0
6
0
8
0.00
-0.00
0.0
1.1
—
112.38
—
0
8
7
71
0.98
-0.00
1.9
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
13.25
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
19.45
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.2
2.9
—
—
—
0
0
7
75
0.93
-0.00
6.4
4.3
21.86
25.01
nmol/l
—
7
75
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_CONGENITAL_NASOLACRIMAL_DUCT_OBSTRUCTION_OR_STENOSIS_WIDE – Congenital nasolacrimal duct obstruction or stenosis, including avohilmo
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).