Other ulcerative colitis

ULCEROTH

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K51.8
  • Cause of death: ICD-10 K51.8

2 out of 7 registries used, show all original rules.

2665

4. Check minimum number of events

None

2665

5. Include endpoints

None

2665

6. Filter based on genotype QC (FinnGen only)

2439

Control definitions (FinnGen only)

Control exclude
K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K51
Name in latin
Alia colitis ulcerosa specificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12782 6042 6700
Only index persons 12237 5850 6387
Unadjusted period prevalence (%)
Whole population 0.18 0.17 0.19
Only index persons 0.23 0.22 0.24
Median age at first event (years)
Whole population 43.13 41.97 44.08
Only index persons 42.48 41.50 43.39

-FinnGen-

Key figures

All Female Male
Number of individuals 2439 1272 1167
Unadjusted period prevalence (%) 0.49 0.45 0.54
Median age at first event (years) 44.73 42.03 47.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2505
Matched controls
25050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L04AB02
ATC
infliximab; parenteral
110.3
321.9
165
16
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.7
318.2
1227
4261
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
307.7
448
*
UJF30
NOMESCO Finland
Ileoscopy through colon
19.3
307.7
1144
1047
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
61.3
307.7
182
32
K51.8
ICD-10 Finland
Other ulcerative colitis
4503599627370496.0
307.7
2504
*
A07EC02
ATC
mesalazine; oral, rectal
2185.9
307.7
2192
80
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
307.7
520
*
A07EA06
ATC
budesonide; oral, local oral
279.9
307.7
1074
67
K50.1
ICD-10 Finland
Crohn disease of large intestine
2330.6
307.7
416
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
307.7
2242
*
H02AB06
ATC
prednisolone; systemic
8.7
307.7
2024
8147
K50.8
ICD-10 Finland
Other Crohn disease
+∞
307.7
488
*
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
+∞
307.7
455
*
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
105.4
307.7
281
30
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
14.0
307.7
751
741
UJF32
NOMESCO Finland
Coloscopy
27.9
307.7
2006
3153
K51.5
ICD-10 Finland
Left sided colitis
16384.0
307.7
1480
*
K50.9
ICD-10 Finland
Crohn disease, unspecified
1565.4
307.7
396
*
K51
ICD-10 Finland
Ulcerative colitis
750.3
307.7
436
7
H02AB07
ATC
prednisone; oral
6.8
307.7
776
1561
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
1187.4
307.7
481
5
A07EC01
ATC
sulfasalazine; oral, rectal
10.5
307.7
697
886
D94
ICPC
Chronic enteritis/ulcerative colitis
286.5
307.7
280
11
A07EA02
ATC
hydrocortisone; rectal
430.2
307.7
871
31
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
605.8
307.7
319
6
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
50.0
307.7
449
109
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
12131.6
307.7
833
*
L01BB02
ATC
mercaptopurine; oral
188.0
307.7
369
23
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
4944.0
307.7
1607
9
L04AX01
ATC
azathioprine; systemic
96.8
307.7
1190
232
ZX120
NOMESCO Finland
Intravenous
6.3
278.2
543
1051
K83.0
ICD-10 Finland
Cholangitis
25.9
275.7
194
81
L04AC05
ATC
ustekinumab; parenteral
99.5
271.9
141
15
L04AB04
ATC
adalimumab; parenteral
13.5
258.6
252
206
K50.0
ICD-10 Finland
Crohn disease of small intestine
+∞
248.1
234
*
J01MA02
ATC
ciprofloxacin; systemic
3.9
247.8
1397
6099
UJF92
NOMESCO Finland
Capsular endoscopy
16.1
234.6
205
138
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.8
229.1
1070
4074
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
49.7
227.5
132
28
A05AA02
ATC
ursodeoxycholic acid; oral
15.3
224.0
201
142
TPH04
NOMESCO Finland
Cathetrisation of vein
3.8
204.3
883
3153
A07EA01
ATC
prednisolone; oral, rectal
690.7
197.0
192
*
P01AB01
ATC
metronidazole; oral, rectal
3.4
196.9
1407
6852
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
43.0
191.9
115
28
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
647.8
185.2
181
*
Z93.2
ICD-10 Finland
Ileostomy status
91.7
185.1
97
11
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
10.7
170.8
191
191
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
163.3
155
*
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
156.9
149
*
A07DA03
ATC
loperamide; oral
9.0
151.2
193
230
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
14.1
148.5
138
103
4AB02, ,
NOMESCO Finland
68.8
146.5
80
12
4AA12, ,
NOMESCO Finland
79.4
144.0
77
10
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
728.1
141.3
138
*
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
141.0
134
*
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
+∞
136.7
130
*
3042, ,
Kela drug reimbursment
+∞
134.6
128
*
253, ,
Kela drug reimbursment
+∞
133.5
127
*
JFF10
NOMESCO Finland
Loop enterostomy
30.7
130.7
86
29
C10AC01
ATC
colestyramine; oral
8.8
129.4
168
204
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
12.7
127.5
126
104
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.5
126.4
261
518
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.0
121.0
736
3094
L04AG05
ATC
vedolizumab; parenteral
+∞
115.5
110
*
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
49.1
115.2
67
14
TJF80
NOMESCO Finland
Ostomy education
15.8
110.6
96
63
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
110.2
105
*
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.8
107.6
261
593
L04AD01
ATC
ciclosporin; systemic
9.0
106.9
135
158
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.9
105.8
201
368
A07AA09
ATC
vancomycin; oral
13.0
103.9
101
81
A06AC01
ATC
ispaghula (psylla seeds); oral
2.7
102.1
777
3624
H02AB09
ATC
hydrocortisone; systemic
7.0
101.7
160
242
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.6
101.1
382
1199
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
7.9
100.3
141
188
WVA20
NOMESCO Finland
Medicine administration
6.5
100.1
168
272
1370
FHL
Colonoscopy, whole colon
41.0
98.9
60
15
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.3
98.2
272
685
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
8.3
97.7
131
165
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
24.0
97.7
70
30
JF1BD
NOMESCO Finland
Very extensive small bowel CT
37.7
95.2
59
16
JFH10
NOMESCO Finland
Total colectomy and ileostomy
464.2
90.8
90
*
L04AB06
ATC
golimumab; parenteral
13.1
87.4
84
66
256, ,
Kela drug reimbursment
+∞
87.0
83
*
L04AA01
ATC
[U] ciclosporin
11.1
86.6
93
87
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
7.2
86.4
132
193
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
48.9
82.3
48
10
K92.1
ICD-10 Finland
Melaena
4.7
81.4
199
453
K56.7
ICD-10 Finland
Ileus, unspecified
9.8
81.4
95
100
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.1
81.4
384
1373
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
79.3
1254
7857
JN3AD
NOMESCO Finland
Abdominal CT examination
2.9
78.6
440
1729
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
18.7
77.9
62
34
A07EC03
ATC
olsalazine; oral
+∞
77.5
74
*
WX002
NOMESCO Finland
Sedation and analgesia
2.6
77.3
556
2481
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.3
77.3
332
1121
K50
ICD-10 Finland
Crohn disease [regional enteritis]
394.3
77.2
77
*
L04AA33
ATC
[U] vedolizumab
+∞
76.4
73
*
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
5.8
72.7
137
248
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
9.6
71.9
85
91
UJG02
NOMESCO Finland
Proctoscopy
6.5
70.7
117
186
L04AF03
ATC
upadacitinib; oral
28.2
69.5
47
17
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
13.3
69.2
66
51
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
+∞
69.1
66
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
5.9
67.1
124
220
JFF13
NOMESCO Finland
Terminal enterostomy
28.6
66.8
45
16
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
+∞
65.9
63
*
A02BC02
ATC
pantoprazole; systemic
2.2
64.9
1772
13241
JAH00
NOMESCO Finland
Laparotomy
5.6
62.6
121
224
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.6
62.5
422
1810
L04AX03
ATC
methotrexate; systemic
2.9
61.8
334
1278
3005
Kela drug reimbursment
Tofacitinib
20.4
60.1
46
23
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
59.5
1041
6564
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
4.4
59.5
155
370
UJK02
NOMESCO Finland
ERCP
5.8
57.5
107
191
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
7.6
57.4
82
111
3AC01, ,
NOMESCO Finland
10.7
56.9
62
59
JFH11
NOMESCO Finland
Laparoscopic colectomy
+∞
56.5
54
*
JF1AD
NOMESCO Finland
Small bowel CT
15.0
56.3
50
34
298, ,
Kela drug reimbursment
18.6
55.2
44
24
JFB00
NOMESCO Finland
Partial resection of small intestine
8.8
55.2
70
82
UJF02
NOMESCO Finland
Peroral enteroscopy
17.6
55.0
45
26
K61.0
ICD-10 Finland
Anal abscess
5.8
53.4
99
176
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
+∞
53.3
51
*
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
22.0
52.6
39
18
3029
Kela drug reimbursment
Upadacitinib
16.6
52.2
44
27
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.0
51.9
244
862
JHA00
NOMESCO Finland
Anal or perianal incision
6.3
50.3
85
138
K60.3
ICD-10 Finland
Anal fistula
5.7
50.0
95
173
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
10.8
49.8
54
51
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
49.1
47
*
WZC30
NOMESCO Finland
Teaching
2.2
49.0
478
2396
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
+∞
48.1
46
*
L04AA29
ATC
[U] tofacitinib
16.9
47.9
40
24
M45
ICD-10 Finland
Ankylosing spondylitis
4.9
45.8
103
218
UJF34
NOMESCO Finland
Left colonoscopy
13.8
45.1
42
31
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.6
44.8
110
250
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
14.5
44.2
40
28
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
43.9
42
*
4AA33, ,
NOMESCO Finland
+∞
43.9
42
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.3
43.6
172
546
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
43.5
628
3628
A02BC01
ATC
omeprazole; systemic
2.0
43.4
661
3889
N02AX02
ATC
tramadol; systemic, rectal
1.8
43.0
1063
7280
WX402
NOMESCO Finland
General anaesthesia
1.9
42.3
644
3783
C05AA08
ATC
fluocortolone; rectal, topical
2.3
41.9
356
1676
A02BC03
ATC
lansoprazole; oral
1.9
41.7
680
4085
Z94.4
ICD-10 Finland
Liver transplant status
14.3
41.7
38
27
R50.9
ICD-10 Finland
Fever, unspecified
2.1
41.2
445
2308
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
6.1
41.1
72
121
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
9.0
41.1
51
58
K56.0
ICD-10 Finland
Paralytic ileus
9.4
41.0
49
53
JHD00
NOMESCO Finland
Anal dilatation
10.2
40.7
46
46
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
6.1
39.9
70
118
J01MA12
ATC
levofloxacin; systemic
2.1
39.9
459
2437
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.4
39.2
99
230
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
6.6
39.2
63
97
L01BA01
ATC
methotrexate; systemic
3.8
38.8
121
329
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
38.6
37
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.6
38.6
248
1028
6419
FHL
Other measure in this category
104.2
37.8
41
*
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
12.0
37.7
38
32
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
6.4
37.3
62
99
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
36.9
310
1450
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.8
36.8
191
710
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
35.9
362
1822
K59.1
ICD-10 Finland
Functional diarrhoea
2.9
35.3
170
606
B01AB05
ATC
enoxaparin; parenteral
1.8
35.3
721
4607
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
7.3
35.2
52
73
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
34.6
268
1208
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
+∞
34.4
33
*
H02AB04
ATC
methylprednisolone; systemic
2.1
34.3
364
1867
UJK12
NOMESCO Finland
Peroral cholangioscopy
50.8
33.5
40
8
Z93
ICD-10 Finland
Artificial opening status
45.1
32.8
40
9
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.6
32.5
203
828
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.7
32.1
178
684
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
39.6
31.2
39
10
D99
ICPC
Disease digestive system other
6.6
30.7
49
75
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
30.5
275
1320
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.0
30.4
138
476
M05BA04
ATC
alendronic acid; oral
2.7
30.3
172
669
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
10.8
29.6
32
30
K52.80
ICD-10 Finland
(Hemorrhagic) colitis caused by antibiotics
+∞
29.2
28
*
ZXC86
NOMESCO Finland
Use of endoscopic device
9.8
28.6
33
34
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.2
28.5
270
1320
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.0
28.4
127
434
ZXE20
NOMESCO Finland
More than three and less than five hours
2.0
28.3
321
1680
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.7
27.7
159
621
SPAT1255
SPAT
Intravenous administration of medicine
2.5
27.7
175
717
SPAT1263
SPAT
Sampling
1.6
27.6
994
7280
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
+∞
27.1
26
*
D16
ICPC
Rectal bleeding
3.6
26.8
89
253
SPAT1262
SPAT
Handing over of treatment supplies
1.9
26.8
393
2246
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
7.6
26.8
38
51
N02BE01
ATC
paracetamol; systemic, rectal
1.9
26.5
2189
19571
E86
ICD-10 Finland
Volume depletion
4.2
26.4
70
169
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
26.1
921
6689
B01AB10
ATC
tinzaparin; parenteral
2.1
25.9
268
1354
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
25.8
914
6640
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.7
25.8
83
231
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
25.4
609
4010
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
30.4
25.0
33
11
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.2
24.7
216
1022
B80
ICPC
Iron deficiency anaemia
3.5
24.6
86
253
JJC00
NOMESCO Finland
Allogenic transplantation of liver
22.2
24.3
35
16
K74.3
ICD-10 Finland
Primary biliary cirrhosis
8.9
24.2
30
34
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
3.9
23.9
71
187
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
5.8
23.7
43
75
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
5.6
23.7
45
82
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
23.4
165
711
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
5.8
23.2
42
73
A02BC05
ATC
esomeprazole; systemic
1.6
23.2
921
6824
127
Kela drug reimbursment
Transplant complication
4.1
22.4
62
155
D11
ICPC
Diarrhoea
1.9
22.3
334
1914
JF2AB
NOMESCO Finland
Colongraphy with X-ray
24.1
22.2
31
13
WW200
NOMESCO Finland
Immunization
3.2
22.1
88
281
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
35.4
22.1
28
8
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
+∞
21.9
21
*
JGB40
NOMESCO Finland
Excision of rectum and end ileostomy
+∞
21.9
21
*
A03CA02
ATC
clidinium and psycholeptics; oral
2.7
21.9
117
441
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
21.9
527
3458
1490
FHL
Sigmoideoscopy (fiberscope)
25.3
21.7
30
12
R4190
NOMESCO Finland
Nutritional therapy
2.7
21.7
123
478
UJD02
NOMESCO Finland
Gastroscopy
2.7
21.6
118
450
J02AC01
ATC
fluconazole; systemic
1.5
21.4
901
6730
WW500
NOMESCO Finland
Blood transfusion
2.9
21.3
103
368
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
21.2
541
3599
M81.4
ICD-10 Finland
Drug-induced osteoporosis
9.0
21.2
26
29
6410
FHL
Panprococolectomy and ileostomy
+∞
20.9
20
*
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
+∞
20.9
20
*
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
4.8
20.8
47
100
Z3231
NOMESCO Finland
Registered nurse
1.6
20.7
616
4250
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.8
20.7
105
385
J01DB01
ATC
cefalexin; oral
1.7
20.6
2040
18199
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
20.1
1057
8244
Z43.2
ICD-10 Finland
Attention to ileostomy
36.1
19.8
25
7
1380
FHL
Colonoscopy, left side
+∞
19.8
19
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
19.7
1035
8057
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.6
19.7
120
483
WX892
NOMESCO Finland
Monitored bed care
2.2
19.7
181
873
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
24.8
19.5
27
11
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
3.1
19.3
80
262
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
16.9
19.2
30
18
B03BA03
ATC
hydroxocobalamin; parenteral
2.6
19.1
113
449
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
4.0
18.9
53
134
UJH02
NOMESCO Finland
Anoscopy
2.7
18.8
105
405
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
+∞
18.8
18
*
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
+∞
18.8
18
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
18.7
259
1444
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
70.4
18.7
21
*
D50.8
ICD-10 Finland
Other iron deficiency anaemias
4.3
18.6
48
114
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
18.5
207
1073
K76.9
ICD-10 Finland
Liver disease, unspecified
4.5
18.5
45
102
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
30.3
18.3
24
8
SPAT1125
SPAT
Stoma care and guidance
4.8
18.2
41
87
TPH04, ,
SPAT
4.8
18.2
41
87
JFA70
NOMESCO Finland
Suture of small intestine
7.6
17.8
25
33
WX704
NOMESCO Finland
Intubation
2.0
17.8
203
1060
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
22.9
17.7
25
11
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
+∞
17.7
17
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
17.7
1002
7869
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
95.7
17.6
19
*
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
5.9
17.4
31
53
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
7.8
17.4
24
31
A02BA02
ATC
ranitidine; systemic
1.7
17.3
372
2357
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.9
17.0
235
1309
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
17.0
337
2089
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.4
17.0
113
475
0093A
ICD-9 Finland
Ill-defined intestinal infections, Diarrhoea of presumed infectious origin
4.0
16.9
47
118
L04AA06
ATC
mycophenolic acid; systemic
3.3
16.8
64
199
E0000UV, ,
ATC
1.4
16.8
964
7564
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
16.8
732
5447
Z93.3
ICD-10 Finland
Colostomy status
6.3
16.7
28
45
D18
ICPC
Change in faeces/bowel movements
2.9
16.7
76
263
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
16.6
218
1194
JKA20
NOMESCO Finland
Cholecystectomy
3.4
16.6
60
181
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
171.1
16.5
17
*
A07AA02
ATC
nystatin; oral
2.3
16.5
123
544
JFH00
NOMESCO Finland
Total colectomy and ileorectal anastomosis
20.2
16.4
24
12
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.0
16.4
71
239
JHD33
NOMESCO Finland
Completing incision of fistula-in-ano
15.4
16.2
26
17
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
12.9
16.1
28
22
D07AC01
ATC
betamethasone; topical
1.5
15.9
815
6249
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.2
15.9
138
651
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.1
15.7
155
768
56902
ICD-8 Finland
Other diseases of intestines and peritoneum, Proctitis haemorrhagica (ulcerosa)
+∞
15.6
15
*
6525
FHL
Enterostomy occlusion
85.6
15.6
17
*
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
13.8
15.5
26
19
ZXD05
NOMESCO Finland
Urgent procedure
1.5
15.4
683
5084
JHD20
NOMESCO Finland
Incision of fistula-in-ano
4.4
15.4
38
87
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.6
15.4
90
356
ZX120, ,
SPAT
4.0
15.3
43
109
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.3
15.2
113
499
N03AX16
ATC
[U] pregabalin
1.5
15.0
481
3347
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.0
14.9
161
824
A06AC51
ATC
ispaghula, combinations; oral
2.4
14.8
105
455
N18.8
ICD-10 Finland
Other chronic renal failure
3.5
14.7
50
145
K60.4
ICD-10 Finland
Rectal fistula
18.5
14.7
22
12
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
14.6
664
4961
K83.1
ICD-10 Finland
Obstruction of bile duct
4.0
14.5
40
100
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
14.5
414
2805
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
6.6
14.5
23
35
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
6.6
14.5
23
35
D07AD01
ATC
clobetasol; topical
1.6
14.4
366
2413
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
2.6
14.4
83
326
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
14.4
249
1484
WX720
NOMESCO Finland
Own respiration
2.2
14.2
123
579
R11
ICD-10 Finland
Nausea and vomiting
1.9
14.2
201
1128
D06BX01
ATC
metronidazole; topical
1.8
14.1
240
1422
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.5
14.1
86
347
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.1
14.0
127
609
TGC00
NOMESCO Finland
Bronchial lavation
2.9
13.8
64
224
K91.8
ICD-10 Finland
Other postprocedural disorders of digestive system, not elsewhere classified
53.6
13.8
16
*
J05AB11
ATC
valaciclovir; oral
1.6
13.7
326
2112
D01
ICPC
Abdominal pain/cramps general
1.7
13.7
299
1896
A07AA11
ATC
rifaximin; oral
10.5
13.7
26
25
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
13.6
13.7
23
17
K63.9
ICD-10 Finland
Disease of intestine, unspecified
6.5
13.6
22
34
L52
ICD-10 Finland
Erythema nodosum
5.1
13.6
28
55
J01DA01
ATC
[U] cefalexin
1.4
13.6
1407
12063
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
+∞
13.6
13
*
Z90.4
ICD-10 Finland
Acquired absence of other parts of digestive tract
+∞
13.6
13
*
NH3EA
NOMESCO Finland
Feet X-ray examination with load
3.2
13.4
52
164
UKC02
NOMESCO Finland
Cystoscopy
1.7
13.4
290
1836
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
18.3
13.4
20
11
K65.0
ICD-10 Finland
Acute peritonitis
4.6
13.3
31
68
JG1JB
NOMESCO Finland
Defekography with X-ray
5.4
13.2
26
49
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
13.9
13.2
22
16
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
3.2
13.2
52
166
L04AD02
ATC
tacrolimus; systemic
3.6
13.1
42
117
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
13.0
434
3036
JAH01
NOMESCO Finland
Laparoscopy
2.2
13.0
111
520
ZXE00
NOMESCO Finland
One hour or less
1.4
13.0
837
6630
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
13.0
155
823
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
12.9
175
969
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
3.9
12.8
37
96
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.6
12.8
71
274
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
14.1
12.7
21
15
A04.9
ICD-10 Finland
Bacterial intestinal infection, unspecified
5.1
12.7
26
51
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.1
12.6
127
634
5551A
ICD-9 Finland
Regional enteritis, Large intestine
+∞
12.5
12
*
6408
FHL
Colectomy and ileostomy
+∞
12.5
12
*
A02BA03
ATC
famotidine; systemic
2.7
12.5
67
254
R10.0
ICD-10 Finland
Acute abdomen
2.5
12.5
81
337
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
12.5
298
1933
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
2.8
12.5
60
215
JFA76
NOMESCO Finland
Closure of fistula of small intestine
130.6
12.4
13
*
N02AA05
ATC
oxycodone; systemic
1.6
12.4
324
2147
B07.9
ICD-10 Finland
Verruca simplex
2.2
12.3
106
498
A01AB09
ATC
miconazole; local oral
1.9
12.3
166
918
R10.2
ICD-10 Finland
Pelvic and perineal pain
2.6
12.3
71
280
A02BA04
ATC
nizatidine; systemic
2.0
12.2
136
705
OAB50, ,
SPAT
1.8
12.1
179
1017
B02.9
ICD-10 Finland
Zoster without complication
2.0
12.1
141
742
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
12.1
462
3321
J01MA01
ATC
ofloxacin; systemic
1.9
12.1
159
872
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
21.4
12.0
17
8
WX004
NOMESCO Finland
Patient-controlled sedation
8.7
12.0
25
29
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
12.0
1971
21097
E000001, ,
ATC
1.5
11.9
435
3097
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
4.7
11.9
27
58
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
5.4
11.8
23
43
5604
FHL
Vascular preparation or cannulation in the operating room
14.7
11.8
19
13
J05AB01
ATC
aciclovir; systemic
1.5
11.7
469
3400
L88
ICD-10 Finland
Pyoderma gangrenosum
16.5
11.7
18
11
R53
ICD-10 Finland
Malaise and fatigue
1.4
11.7
563
4228
ZX100
NOMESCO Finland
Oral
3.6
11.6
37
103
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
3.3
11.5
43
133
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.9
11.5
147
799
JGB61
NOMESCO Finland
Laparoscopic excision of rectum and ileoanal anastomosis
+∞
11.5
11
*
K52.0
ICD-10 Finland
Gastroenteritis and colitis due to radiation
+∞
11.5
11
*
4AC05, ,
NOMESCO Finland
+∞
11.5
11
*
5563A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctosigmoiditis
+∞
11.5
11
*
M25.5
ICD-10 Finland
Pain in joint
1.4
11.3
768
6106
H26.3
ICD-10 Finland
Drug-induced cataract
5.1
11.3
23
45
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
11.3
187
1101
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
11.2
321
2168
K43.0
ICD-10 Finland
Incisional hernia with obstruction, without gangrene
4.8
11.2
25
53
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
5.6
11.2
21
38
M13.9
ICD-10 Finland
Arthritis, unspecified
1.8
11.0
168
964
SPAT1312
SPAT
General health counselling
1.4
11.0
677
5293
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
11.0
1740
15674
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
11.0
447
3249
SPAT1153
SPAT
Removal of sutures
1.4
10.9
612
4708
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.3
10.9
82
365
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
10.9
470
3454
R06.0
ICD-10 Finland
Dyspnoea
1.4
10.8
539
4063
K85
ICD-10 Finland
Acute pancreatitis
3.3
10.8
40
123
K86.1
ICD-10 Finland
Other chronic pancreatitis
4.2
10.8
28
67
D07AC13
ATC
mometasone; topical
1.4
10.8
619
4782
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.9
10.8
127
672
JFB30
NOMESCO Finland
Right hemicolectomy
3.8
10.8
32
85
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.1
10.8
102
499
R15
ICD-10 Finland
Faecal incontinence
2.7
10.7
55
204
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.5
10.7
63
251
JFG96
NOMESCO Finland
Other operation on intestinal stoma or pouch
60.3
10.6
12
*
N05CF01
ATC
zopiclone; oral
1.4
10.6
625
4849
WX199
NOMESCO Finland
Other local analgesia
2.4
10.6
71
301
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
10.5
294
1977
D17
ICPC
Incontinence of bowel
4.8
10.5
23
48
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
10.5
137
750
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
2.8
10.4
50
179
SPAT1260
SPAT
Consultation of another employee
1.5
10.4
343
2387
JF1DM
NOMESCO Finland
Very extensive MRI of small bowel (more than 1.5 T)
110.5
10.4
11
*
Z93.8
ICD-10 Finland
Other artificial opening status
+∞
10.4
10
*
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
+∞
10.4
10
*
K90.0
ICD-10 Finland
Coeliac disease
2.4
10.4
68
285
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
23.5
10.2
14
6
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
10.2
228
1454
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
2.5
10.1
62
252
D05AX52
ATC
calcipotriol, combinations; topical
1.9
10.1
116
609
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
4.8
10.0
22
46
C05AA01
ATC
hydrocortisone; rectal, topical
2.1
9.9
96
474
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
9.9
233
1505
JF1CM
NOMESCO Finland
Small bowel extensive MRI with with high intensity magnet
26.1
9.8
13
5
SPAT1301
SPAT
No procedures
1.4
9.8
611
4773
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.6
9.8
221
1412
SPAT1104
SPAT
Monitoring of emergency patient
1.9
9.7
123
667
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.8
9.7
138
777
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
9.7
1646
14820
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
9.7
224
1441
K14.1
ICD-10 Finland
Geographic tongue
5.0
9.6
20
40
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
8.4
9.5
20
24
XQ802
NOMESCO Finland
Epicutan test
2.0
9.5
97
489
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.1
9.5
92
455
SPAT1254
SPAT
Administration of medicine
1.5
9.5
274
1855
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
9.4
834
6859
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
9.4
745
6029
S18
ICPC
Laceration/cut
1.3
9.4
996
8397
K61.1
ICD-10 Finland
Rectal abscess
7.6
9.4
21
28
C10AC02
ATC
colestipol; oral
17.6
9.4
14
8
ZYC01
NOMESCO Finland
Remote contact by phone
1.7
9.4
154
904
J01FF01
ATC
clindamycin; systemic
1.4
9.4
568
4412
5589X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis, Other and unspecified non-infectious gastro-enteritis and colitis
+∞
9.4
9
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.7
9.4
50
190
JN4AD
NOMESCO Finland
Body CT examination
1.6
9.3
215
1380
N82.3
ICD-10 Finland
Fistula of vagina to large intestine
21.8
9.3
13
6
J01FA10
ATC
azithromycin; systemic
1.3
9.3
1352
11880
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
2.9
9.3
42
146
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
9.5
9.3
18
19
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.2
9.3
72
326
SFA10
NOMESCO Finland
One-surface restoration
1.3
9.2
1314
11517
B81
ICPC
Anaemia vit B12/folate deficiency
2.3
9.2
66
289
A41.9
ICD-10 Finland
Sepsis, unspecified
2.3
9.2
66
289
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
4.2
9.2
24
58
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
9.2
124
687
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
2.1
9.1
84
407
A41.8
ICD-10 Finland
Other specified sepsis
3.0
9.1
40
137
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
2.5
9.1
53
211
K63.0
ICD-10 Finland
Abscess of intestine
15.6
9.0
14
9
Z50.1
ICD-10 Finland
Other physical therapy
1.9
9.0
106
561
K52.2
ICD-10 Finland
Allergic and dietetic gastroenteritis and colitis
36.8
9.0
11
*
K62.4
ICD-10 Finland
Stenosis of anus and rectum
10.1
9.0
17
17
WX725
NOMESCO Finland
Noninvasive ventilation
1.8
8.9
125
700
K43.5
ICD-10 Finland
Parastomal hernia without obstruction or gangrene
18.7
8.9
13
7
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
7.5
8.9
20
27
JAD10
NOMESCO Finland
Repair of incisional hernia
4.3
8.9
22
51
B01AA03
ATC
warfarin; systemic
1.5
8.7
271
1861
GD1AD
NOMESCO Finland
Thorax CT examination
1.8
8.7
125
705
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
3.0
8.7
37
124
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.1
8.7
81
394
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
8.7
213
1388
E000003, ,
ATC
2.0
8.7
93
477
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
50.2
8.7
10
*
WVA30
NOMESCO Finland
Intramuscular and subcutaneous injection
4.3
8.7
22
52
J01FA06
ATC
roxithromycin; oral
1.3
8.6
821
6801
H20.1
ICD-10 Finland
Chronic iridocyclitis
3.4
8.6
30
89
UDC00
NOMESCO Finland
Ear microscopy
1.7
8.6
150
896
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
2.6
8.6
47
181
JJ5AT, ,
NOMESCO Finland
16.3
8.5
13
8
E000002, ,
ATC
1.5
8.5
232
1549
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.6
8.5
202
1308
C03CA01
ATC
furosemide; systemic
1.4
8.4
430
3243
Z2221
NOMESCO Finland
Medical doctor
1.3
8.4
564
4442
N82.4
ICD-10 Finland
Other female intestinal-genital tract fistulae
90.4
8.4
9
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
8.4
306
2171
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
8.4
610
4863
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.5
8.4
230
1539
6437
FHL
Rectum resection and sphincter-sparing through-anastomosis
+∞
8.3
8
*
1CB02, ,
NOMESCO Finland
+∞
8.3
8
*
JFG70
NOMESCO Finland
Conversion of continent ileostomy to conventional ileostomy
+∞
8.3
8
*
A10AB05
ATC
insulin aspart; parenteral
1.7
8.3
162
999
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
1.9
8.2
96
507
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.9
8.2
95
500
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
3.5
8.2
27
77
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
4.4
8.1
20
46
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.5
8.1
221
1477
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
3.2
8.1
31
98
SPAT1325
SPAT
Vaccination
1.3
8.1
599
4786
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
8.1
354
2600
D28
ICPC
Limited function/disability (D)
10.1
8.0
15
15
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.8
8.0
123
709
K29.7
ICD-10 Finland
Gastritis, unspecified
2.1
8.0
71
340
A12BA01
ATC
potassium chloride; oral
2.3
8.0
56
243
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
8.0
254
1754
XQ848
NOMESCO Finland
Dermatological photography
2.2
7.9
62
282
WVA20, ,
SPAT
2.0
7.9
81
409
JWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in gastroenterological surgery
13.1
7.9
13
10
L04AF01
ATC
tofacitinib; oral
13.1
7.9
13
10
R4135
NOMESCO Finland
Rehabilitation for hearing problems
3.0
7.8
34
116
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
7.8
595
4769
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
4.1
7.8
21
52
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.6
7.8
182
1173
RD210, ,
NOMESCO Finland
2.6
7.8
42
161
R01AD08
ATC
fluticasone; nasal
1.3
7.8
633
5122
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
7.7
180
1159
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.5
7.7
206
1369
A01AB04
ATC
amphotericin B; local oral
2.1
7.7
74
365
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
7.7
416
3163
JFH01
NOMESCO Finland
Laparoscopic colectomy with ileorectal anastomosis
45.1
7.7
9
*
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.7
7.7
133
794
UJF30, ,
SPAT
3.4
7.7
26
76
K56.2
ICD-10 Finland
Volvulus
4.5
7.6
18
40
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
7.6
367
2739
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.4
7.6
48
199
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
3.1
7.6
31
102
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.5
7.6
236
1622
JH1CM
NOMESCO Finland
Perianal extensive MRI with 3 Tesla magnet
25.1
7.6
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
7.5
691
5678
ZX114
NOMESCO Finland
Intramuscular
2.7
7.5
38
141
A10BH05
ATC
linagliptin; oral
2.0
7.5
82
425
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
2.0
7.4
75
377
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
7.4
524
4149
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.3
7.4
56
251
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.1
7.4
67
323
3048, ,
Kela drug reimbursment
80.3
7.4
8
*
255, ,
Kela drug reimbursment
80.3
7.4
8
*
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
3.4
7.4
26
78
E87.6
ICD-10 Finland
Hypokalaemia
2.1
7.4
65
311
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.7
7.3
263
3633
JL5AM
NOMESCO Finland
Bile and pancreas ducts simple MRI examination with 3 Tesla magnet
+∞
7.3
7
*
L04AA45
ATC
[U] filgotinib
+∞
7.3
7
*
JFG53
NOMESCO Finland
Revision of ileal pelvic pouch
+∞
7.3
7
*
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.8
7.3
115
670
A04.5
ICD-10 Finland
Campylobacter enteritis
3.4
7.2
25
74
JFA56
NOMESCO Finland
Faecal microbiota transplantation
15.8
7.2
11
7
N02BF02
ATC
pregabalin; oral
1.6
7.2
144
894
L71.8
ICD-10 Finland
Other rosacea
2.6
7.2
41
162
EBA10
NOMESCO Finland
Operative extraction of tooth
1.4
7.2
329
2434
R52.9
ICD-10 Finland
Pain, unspecified
1.5
7.1
212
1443
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
3.1
7.1
28
90
JAK03
NOMESCO Finland
Laparotomy and peritoneal irrigation
20.1
7.1
10
5
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
3.8
7.1
21
56
JHD96
NOMESCO Finland
Other incision of anal sphincter
12.1
7.1
12
10
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.6
7.0
39
152
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
10.0
7.0
13
13
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.3
7.0
50
219
A10AE05
ATC
insulin detemir; parenteral
1.8
7.0
110
639
M05BB03
ATC
alendronic acid and colecalciferol; oral
2.8
7.0
33
118
D04
ICPC
Rectal/anal pain
2.6
7.0
37
141
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
3.2
7.0
26
81
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.0
6.9
69
346
Z01.2
ICD-10 Finland
Dental examination
1.3
6.9
1072
9371
A01AB10
ATC
natamycin; local oral
2.2
6.9
58
273
J01CF05
ATC
flucloxacillin; systemic
1.6
6.9
153
976
L88
ICPC
Rheumatoid/seropositive arthritis
1.9
6.9
80
424
71240
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Spondylitis ankylopoietica
8.3
6.8
14
17
B82
ICPC
Anaemia other/unspecified
2.2
6.8
52
235
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
6.8
373
2841
H25.8
ICD-10 Finland
Other senile cataract
1.6
6.8
143
900
E87.5
ICD-10 Finland
Hyperkalaemia
2.7
6.8
34
126
A02.0
ICD-10 Finland
Salmonella enteritis
4.3
6.7
17
40
1470
FHL
Rectoscopy
4.3
6.7
17
40
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
16.7
6.7
10
6
R03AC02
ATC
salbutamol; inhalant
1.2
6.7
1221
10849
D02AE01
ATC
carbamide; topical
1.7
6.7
123
747
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
2.5
6.7
39
156
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.8
6.7
92
515
A10AE04
ATC
insulin glargine; parenteral
1.5
6.7
186
1250
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.5
6.6
212
1465
S97
ICPC
Chronic ulcer skin
1.7
6.6
105
613
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.6
6.6
169
1114
SFA20
NOMESCO Finland
Two-surface restoration
1.2
6.6
1387
12511
XF602
NOMESCO Finland
Bloodpressure monitoring
3.1
6.6
26
84
J01MA14
ATC
moxifloxacin; systemic
1.6
6.6
170
1123
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.6
1421
12855
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.6
578
4711
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
6.6
162
1059
R05
ICPC
Cough
1.3
6.5
522
4200
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
10.0
6.5
12
12
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
6.9
6.5
15
22
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
6.5
547
4431
SPAT1138
SPAT
Guidance concerning bowel function
2.9
6.5
29
101
T81.9
ICD-10 Finland
Unspecified complication of procedure
2.4
6.4
40
165
JAK00
NOMESCO Finland
Laparotomy and drainage of peritoneal cavity
70.0
6.4
7
*
N77.1*B37.3
ICD-10 Finland
Candidiasis of vulva and vagina
2.2
6.4
50
228
A03DA02
ATC
pitofenone and analgesics; systemic
2.8
6.4
30
107
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.4
6.4
43
184
107
Kela drug reimbursment
Pernicious anaemia
2.8
6.4
31
113
R01AD09
ATC
mometasone; nasal
1.2
6.4
1026
8978
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
1.8
6.4
97
560
WZA90
NOMESCO Finland
Other medical or dental certificate
1.3
6.4
497
3986
EB1VA, ,
NOMESCO Finland
1.3
6.3
397
3085
JJA20
NOMESCO Finland
Open biopsy of liver
6.6
6.3
15
23
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
2.8
6.3
30
108
R51.80
ICD-10 Finland
Headache
1.4
6.3
346
2634
K62.9
ICD-10 Finland
Disease of anus and rectum, unspecified
3.6
6.3
20
56
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
6.3
274
2007
JWW96
NOMESCO Finland
Other reoperation in gastroenterological surgery
11.0
6.3
11
10
N03AX12
ATC
[U] gabapentin; oral
1.4
6.3
304
2268
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
2.4
6.3
39
161
ZXH04
NOMESCO Finland
Procedure performed in other inpatient unit
3.9
6.3
18
47
LEE20
NOMESCO Finland
Closure of urovaginal fistula using graft or flap
+∞
6.3
6
*
N06AX21
ATC
duloxetine; oral
1.4
6.2
253
1831
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
2.2
6.2
50
231
K60.1
ICD-10 Finland
Chronic anal fissure
2.1
6.2
53
251
R06AE07
ATC
cetirizine; oral
1.2
6.2
961
8367
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
3.7
6.2
19
52
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
2.5
6.2
36
144
A04
ICPC
Weakness/tiredness general
1.4
6.2
320
2414
K72.9
ICD-10 Finland
Hepatic failure, unspecified
5.3
6.1
17
32
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.5
6.1
195
1347
R42
ICD-10 Finland
Dizziness and giddiness
1.3
6.1
412
3234
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
7.7
6.1
13
17
TQW40
NOMESCO Finland
Remowal of suture of skin
1.6
6.1
138
884
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
2.5
6.1
37
151
UDM02
NOMESCO Finland
Sinoscopy
2.2
6.1
48
220
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
6.1
1269
11393
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.8
6.1
85
478
B02.8
ICD-10 Finland
Zoster with other complications
4.1
6.1
16
39
N06AB04
ATC
citalopram; systemic
1.3
6.1
402
3148
-44
ICPC
Preventive immunization/medic
1.6
6.1
133
846
K56.1
ICD-10 Finland
Intussusception
5.2
6.0
17
33
J01EA01
ATC
trimethoprim; systemic
1.3
6.0
442
3514

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1959
9410
5.96
307.65
4.9
2.3
74.10
75.22
nmol/l
1.13
1908
8650
1503
1972
17.55
307.65
2.6
1.2
—
—
—
0
0
2061
8626
8.84
307.65
12.9
4.7
36.46
36.34
g/l
0.54
2027
8107
316
25
144.50
307.65
3.9
2.4
8.51
5.34
mg/l
2.61
271
18
1987
2504
34.54
307.65
8.8
1.3
237.70
88.94
ug/g
44.56
1917
1932
283
25
127.49
307.65
3.1
2.4
87.67
193.11
au/ml
—
51
8
2081
11023
6.25
303.99
17.0
6.0
0.58
0.57
e9/l
0.77
1970
9543
2081
11039
6.23
302.97
17.0
6.1
0.04
0.04
e9/l
2.83
1970
9552
1969
10092
5.44
296.29
16.8
6.3
8.91
8.72
%
2.52
1914
9500
2106
11414
6.31
294.73
17.1
6.4
0.19
0.19
e9/l
0.08
1989
10054
1961
10072
5.36
292.77
16.7
6.2
2.83
2.82
%
0.08
1907
9471
2093
11319
6.16
292.71
17.1
6.1
1.85
1.96
e9/l
3.72
1999
10055
1958
10074
5.32
290.82
16.9
6.3
0.75
0.68
%
7.90
1905
9471
736
1821
5.31
288.29
8.5
4.4
0.71
0.95
%
1.49
245
523
1969
10236
5.32
286.78
16.1
6.1
57.51
56.81
%
2.17
1930
9810
710
1727
5.34
283.27
7.8
4.2
0.43
0.73
%
2.18
220
490
1975
10415
5.24
278.83
16.8
6.2
28.14
28.49
%
0.85
1935
9907
1297
5141
4.16
271.03
4.4
2.1
2.93
2.71
mg/l
3.08
1223
4440
702
1772
5.11
266.67
9.0
4.7
0.46
0.32
%
0.12
198
414
696
1752
5.12
265.14
8.8
4.4
0.05
0.11
%
1.79
204
454
2120
12278
5.73
252.75
18.9
9.5
3.97
4.08
e9/l
1.62
2013
10695
154
42
39.00
250.19
2.7
1.3
9.32
8.60
mg/l
0.35
133
33
2384
15922
11.30
222.86
22.9
7.5
78.21
77.07
u/l
0.67
2352
15165
345
607
6.43
191.79
2.1
1.2
74.65
108.57
titre
1.36
43
63
803
2809
3.74
189.77
3.2
2.6
21.14
24.18
%
7.90
779
2631
1161
5224
3.28
181.77
12.8
4.2
—
—
—
0
0
835
3073
3.58
181.48
3.3
2.5
2.43
2.35
g/l
3.84
807
2862
763
2660
3.69
180.08
3.9
3.2
4.00
4.75
e9/l
2.15
695
2355
866
3319
3.46
175.71
3.4
2.5
12.62
14.05
umol/l
6.33
846
3110
456
1143
4.65
169.33
1.6
1.2
—
—
—
0
0
468
1305
4.18
150.13
2.2
1.9
1.23
1.33
g/l
0.67
446
1209
2218
15647
4.64
148.79
9.5
4.0
12.74
10.36
mm/h
12.98
2123
14776
224
330
7.36
146.60
5.7
3.2
3.93
4.12
e9/l
0.57
224
330
139
0
+∞
146.30
3.0
0.0
23.39
—
mg/l
—
134
0
1748
10748
3.07
145.38
10.7
6.4
10.34
11.44
umol/l
5.15
1699
10283
1259
6519
2.87
144.61
5.1
2.6
63.05
58.63
u/l
1.04
1211
6068
1384
7590
2.84
141.43
6.2
3.3
32.95
34.30
u/l
0.18
1304
7199
767
3077
3.15
139.66
1.6
1.7
—
—
—
0
0
530
1697
3.69
138.79
3.2
2.8
11.61
10.58
g/l
6.35
505
1573
242
431
6.11
131.61
5.6
3.0
58.21
57.46
%
0.35
242
431
254
484
5.73
128.60
1.4
1.3
268.70
252.11
u/ml
0.32
142
306
1570
9614
2.70
122.30
23.2
10.4
0.00
0.00
e9/l
0.91
1434
7843
1472
8845
2.61
117.37
15.2
12.3
1.15
1.19
inr
3.12
1293
7357
528
1862
3.33
117.31
4.3
2.2
0.23
0.22
g/l
1.98
504
1740
209
365
6.16
115.69
2.6
1.6
0.78
0.88
g/l
0.44
179
280
1678
10837
2.66
113.52
5.2
3.0
107.42
114.83
ug/l
0.44
1622
10260
901
4338
2.68
112.90
1.7
1.7
—
—
—
0
0
733
3219
2.81
109.57
1.8
1.3
506.02
476.24
titre
0.18
226
639
133
165
8.46
100.47
1.6
1.1
362.45
144.29
titre
1.79
53
21
133
165
8.46
100.47
1.6
1.1
245.00
270.00
titre
—
6
6
307
860
3.93
95.85
1.4
1.3
—
—
—
0
0
979
5274
2.41
92.80
5.5
4.3
—
—
—
0
0
276
743
4.05
90.94
1.9
1.2
—
—
—
0
0
253
640
4.28
90.65
6.1
3.4
230.57
2404.57
u/ml
0.79
232
555
224
538
4.47
85.74
2.0
1.2
4.42
6.42
iu/ml
—
6
9
1500
9924
2.27
84.87
9.3
7.2
1.21
1.21
mmol/l
0.47
1329
8615
292
865
3.69
83.68
2.1
1.6
4.95
24.09
iu/ml
1.34
36
21
110
146
7.83
78.40
1.9
1.5
—
—
—
0
0
261
754
3.75
77.43
1.9
1.8
—
—
—
0
0
162
334
5.12
74.46
1.2
1.2
—
—
—
0
0
749
3968
2.27
70.03
2.4
1.6
16077129.85
45013738.49
pmol/l
0.86
678
3379
141
283
5.22
66.76
4.5
2.8
5.40
62.11
u/ml
0.72
141
278
579
2892
2.30
61.20
2.1
1.7
1163.52
1173.06
nmol/l
0.07
440
2257
1664
12301
2.05
60.52
6.7
5.0
6.59
6.60
mmol/l
0.07
1598
11599
821
4747
2.09
59.74
2.0
1.5
2.52
2.35
g/l
2.25
644
3089
133
282
4.92
59.05
3.1
3.6
1.24
1.59
%
0.47
121
265
1852
14353
2.11
57.65
5.9
4.2
—
3.45
—
0
18
405
1771
2.54
57.31
6.4
4.3
6.15
21.23
ug/l
1.84
320
1425
2432
21458
5.58
57.07
36.3
13.6
16.48
23.16
mg/l
35.22
2277
17387
154
378
4.28
56.97
4.7
4.1
—
—
—
0
0
1271
8699
1.94
56.06
2.4
2.0
96.94
97.14
pmol/l
0.05
824
4764
1232
8354
1.93
55.79
2.8
2.0
—
—
—
0
0
70
85
8.44
53.63
27.0
29.1
123.84
126.95
ug/l
0.10
63
67
1275
8878
1.89
51.91
7.9
6.6
1.21
1.21
mmol/l
0.31
1214
8250
95
167
5.87
51.87
1.8
1.5
11.33
11.86
umol/l
0.36
95
155
875
5401
1.95
51.37
1.8
2.0
—
—
—
0
0
143
361
4.14
50.92
6.7
3.9
33.04
1136.93
u/ml
0.93
130
338
987
6360
1.91
50.78
4.6
2.9
0.01
0.19
estimate
0.72
386
1833
130
313
4.33
49.26
1.2
1.1
1.50
1.48
g/l
0.20
121
284
480
2408
2.23
49.11
5.2
2.8
6.91
7.55
umol/l
0.40
435
2122
1238
8642
1.86
49.01
4.9
3.4
0.03
0.08
estimate
0.43
397
1897
672
3845
2.02
48.61
4.0
2.8
540.83
538.61
mosm/kgh2o
0.08
631
3366
449
2206
2.26
48.26
2.7
2.2
326.35
380.70
nmol/l
7.23
427
2062
417
2001
2.30
47.34
5.8
3.9
7.37
7.38
ph
0.76
290
1133
404
1921
2.32
46.82
5.7
3.9
1.74
1.84
mmol/l
0.23
351
1659
226
811
2.96
46.60
5.8
3.5
24.95
25.29
mmol/l
0.66
218
777
1514
11395
1.83
45.51
5.0
3.6
0.01
0.15
estimate
0.53
450
2152
79
133
6.10
45.07
1.1
1.1
1511.87
1500.35
miu/ml
0.03
79
133
1505
11335
1.82
44.83
5.0
3.5
3.51
4.96
estimate
0.14
468
2312
1493
11218
1.82
44.82
4.9
3.5
0.00
0.00
estimate
0.80
463
2284
408
1983
2.26
44.75
5.8
3.9
5.83
5.85
kpa
0.14
401
1924
548
2992
2.06
44.63
2.5
2.1
—
—
—
0
0
844
5424
1.84
41.88
1.9
1.6
19.36
19.94
nmol/l
0.58
776
4697
895
5883
1.81
41.06
4.8
4.2
7.39
7.40
ph
1.40
697
4148
159
506
3.29
40.15
1.4
1.5
—
—
—
0
0
84
171
5.05
39.06
1.1
1.1
—
—
—
0
0
209
793
2.78
38.73
5.1
5.0
0.95
0.88
%
1.62
204
744
1333
9939
1.73
38.58
3.7
2.7
—
—
estimate
—
0
0
399
2046
2.13
37.84
3.9
2.4
40.85
61.72
u/l
0.42
369
1739
899
6057
1.76
37.00
4.8
3.7
0.00
0.00
estimate
0.35
428
2136
217
873
2.63
35.80
5.1
4.8
1.56
1.62
%
0.35
212
823
146
473
3.22
35.77
1.4
1.5
135.72
148.69
au/ml
0.43
29
139
1228
9078
1.69
35.59
3.9
3.2
6.12
6.20
ph
1.96
831
5231
161
559
3.01
35.05
1.5
1.1
—
—
—
0
0
339
1680
2.18
34.91
4.6
3.6
—
—
—
0
0
2359
21385
2.77
33.17
27.8
15.7
139.31
139.68
mmol/l
13.81
2331
20980
485
2803
1.91
32.43
1.3
1.2
—
—
—
0
0
2360
21448
2.73
32.08
28.0
15.8
3.92
3.96
mmol/l
9.19
2327
21001
329
1666
2.12
31.91
5.1
3.2
4.47
4.71
kpa
1.33
323
1615
153
552
2.89
31.07
1.5
1.4
294.18
294.59
ug/g
0.01
92
313
382
2088
1.98
29.95
3.7
2.9
1.90
1.78
%
1.39
353
1895
314
1599
2.10
29.92
3.1
2.5
0.35
0.43
e6/l
0.33
302
1518
957
6845
1.64
29.88
3.4
2.3
—
—
—
0
0
555
3424
1.80
29.84
5.5
3.6
0.81
0.82
mmol/l
1.67
528
3264
457
2656
1.88
29.80
9.0
6.4
1.03
1.04
mmol/l
0.21
441
2482
88
232
3.89
29.50
1.4
1.3
—
—
—
0
0
208
898
2.44
29.47
4.8
3.1
1.02
1.02
ratio
1.79
202
818
805
5542
1.67
28.99
3.5
2.8
—
—
—
0
0
258
1232
2.22
28.92
5.1
3.2
128.70
132.02
g/l
1.46
247
1196
2448
22858
4.12
28.62
39.9
17.0
79.17
75.82
umol/l
4.28
2437
22621
87
233
3.83
28.53
1.4
1.3
0.38
0.38
g/l
0.05
60
163
87
233
3.83
28.53
1.4
1.3
3.21
3.01
g/l
0.38
60
165
87
233
3.83
28.53
1.4
1.3
8.00
6.70
g/l
1.47
60
164
341
1822
2.01
28.43
11.3
8.1
9.42
8.91
mmol/l
0.66
330
1762
34
37
9.30
28.29
3.2
2.9
4.82
5.08
ug/l
0.10
34
37
179
745
2.51
27.42
2.2
2.0
8.80
1.76
ug/l
0.44
163
670
676
4509
1.68
27.15
3.3
2.6
5.03
6.07
e6/l
1.57
643
4101
2439
22787
3.67
27.13
29.5
10.7
27.64
27.57
u/l
0.07
2422
22268
119
406
3.03
26.69
1.2
1.1
—
—
—
0
0
72
178
4.14
26.36
3.0
3.6
57.22
54.19
%
0.52
60
160
784
5468
1.63
26.29
1.4
1.3
1.20
1.65
u/ml
0.85
229
1585
768
5330
1.64
26.27
7.6
4.0
94.88
91.92
%
3.02
750
5229
52
99
5.34
26.10
1.8
1.6
2804.71
2781.54
titre
0.01
17
13
316
1693
1.99
26.03
1.5
1.4
—
—
—
0
0
371
2100
1.90
25.98
1.4
1.5
—
—
—
0
0
298
1568
2.02
25.82
2.9
2.9
76.93
71.53
e9/l
1.20
236
1143
290
1515
2.03
25.63
5.7
3.6
1.23
1.23
mmol/l
0.10
270
1303
913
6659
1.58
25.16
4.2
3.2
73.82
77.59
e6/l
0.03
784
5020
166
696
2.48
25.01
5.1
3.7
1.49
1.43
mg/l
0.40
156
643
2085
18461
1.77
24.72
38.0
16.8
13.80
13.45
%
28.78
2077
18229
884
6425
1.58
24.59
11.0
6.1
—
—
—
0
0
28
5
56.59
24.04
1.1
1.0
—
—
—
0
0
41
68
6.11
23.76
4.1
2.9
0.61
0.62
mmol/l
0.26
41
68
1620
13532
1.56
23.68
5.3
4.2
384.72
1490.29
e6/l
1.15
18
175
421
2551
1.78
23.50
2.0
1.7
—
—
—
0
0
798
5726
1.58
23.15
4.0
3.1
0.43
0.42
e6/l
0.09
669
4122
993
7550
1.52
21.86
4.0
3.4
35.39
53.37
ng/l
0.83
670
4774
180
835
2.25
21.54
1.7
1.9
1.54
1.48
g/l
0.37
159
739
1009
7755
1.50
20.80
4.8
3.8
96.67
75.60
e6/l
0.21
820
5353
67
191
3.58
20.12
1.1
1.1
289.05
286.47
mg/l
0.10
59
172
242
1313
1.93
19.02
5.7
3.6
5.05
5.15
kpa
1.24
235
1267
189
954
2.06
18.21
1.1
1.1
—
—
—
0
0
706
5167
1.51
17.79
3.3
2.3
—
—
—
0
0
230
1276
1.88
16.86
5.8
3.6
7.41
7.41
ph
0.36
200
1076
132
596
2.28
16.85
6.0
5.6
1.34
1.30
mmol/l
0.16
123
517
187
968
2.01
16.81
1.7
1.8
5.52
6.32
iu/ml
0.23
46
237
139
647
2.22
16.50
1.2
1.3
—
—
—
0
0
101
408
2.54
16.50
1.1
1.1
—
—
—
0
0
738
5533
1.47
16.23
3.7
3.0
0.67
0.00
estimate
—
9
19
120
534
2.31
15.86
4.0
3.0
1.71
2.00
index
0.31
68
295
290
1763
1.73
15.65
4.7
4.0
7.36
7.35
ph
0.33
237
1284
667
4946
1.48
15.36
1.9
1.8
1.10
1.05
mg/l
0.24
530
3713
817
6307
1.44
15.20
3.8
2.7
0.08
0.02
0.66
36
101
214
1203
1.85
15.03
7.0
7.0
23.77
24.40
mmol/l
1.71
202
1153
355
2307
1.63
14.83
8.6
8.5
4.91
5.10
kpa
3.54
334
2225
355
2308
1.63
14.81
8.8
8.6
7.42
7.41
ph
0.44
221
1271
355
2308
1.63
14.81
8.5
8.5
12.46
12.67
kpa
0.33
335
2229
403
2708
1.58
14.64
1.7
1.5
—
—
—
0
0
60
196
3.11
14.60
1.7
2.6
1318.57
1304.57
e6/l
0.03
49
175
56
176
3.23
14.52
3.7
4.2
—
—
—
0
0
321
2049
1.65
14.38
9.0
9.0
96.09
95.81
%
0.37
303
1984
351
2292
1.62
14.36
8.6
8.5
0.81
0.85
mmol/l
0.06
266
1884
100
437
2.34
13.81
4.6
3.7
—
—
—
0
0
470
3308
1.52
13.80
3.5
2.9
2.99
2.42
e6/l
0.61
296
1561
141
708
2.05
13.79
1.5
1.7
1.21
1.20
g/l
0.25
129
675
131
640
2.10
13.78
3.9
3.7
7.40
7.41
ph
2.40
131
633
104
464
2.30
13.69
3.6
2.3
127.94
131.64
g/l
0.96
89
368
283
1774
1.67
13.58
10.9
9.9
—
—
—
0
0
102
455
2.29
13.44
3.8
3.1
29.80
35.92
umol/l
1.87
96
422
135
679
2.04
13.15
1.5
1.7
0.22
0.24
g/l
1.18
123
648
301
1941
1.63
12.90
9.5
9.3
120.24
123.64
g/l
2.14
292
1900
865
6900
1.39
12.82
4.3
3.4
2.33
2.35
mmol/l
5.92
800
6358
1786
16008
1.40
12.72
6.1
3.3
60.30
44.63
u/l
10.72
1723
15296
660
5053
1.42
12.36
4.6
3.6
1.02
1.63
kg/l
0.80
489
3318
206
1215
1.76
12.32
5.1
3.9
23.98
24.22
mmol/l
0.54
206
1202
532
3955
1.44
11.64
1.3
1.3
7.34
10.63
u/ml
0.83
214
1628
242
1526
1.65
11.31
2.1
2.8
67.10
66.93
g/l
0.13
235
1426
106
516
2.10
11.30
7.6
3.1
8.84
8.39
kpa
2.24
101
504
22
23
9.64
11.23
2.1
1.6
—
—
—
0
0
783
6268
1.36
10.97
2.3
2.2
279.97
229.49
u/l
0.21
751
5989
2451
23744
2.50
10.65
48.5
20.9
273.29
253.22
e9/l
37.01
2438
23351
253
1643
1.60
10.49
1.5
1.3
196.83
209.38
u/ml
0.09
237
1538
2451
23753
2.48
10.47
48.1
20.8
91.30
90.55
fl
13.62
2442
23561
482
3581
1.43
10.47
3.4
2.8
1.24
1.05
e6/l
0.28
308
1832
2451
23755
2.47
10.44
48.1
20.8
30.34
30.26
pg
1.39
2442
23563
2451
23757
2.47
10.40
48.3
20.8
4.47
4.58
e12/l
23.02
2434
23311
2451
23758
2.47
10.38
49.0
21.3
40.33
41.37
%
3.60
2441
23556
2451
23764
2.46
10.26
48.7
21.0
134.57
137.65
g/l
22.22
2445
23574
76
338
2.29
10.16
2.5
2.2
19.94
5.84
umol/l
1.76
60
245
2450
23763
2.41
10.02
48.5
20.9
6.90
6.71
e9/l
3.51
2432
23309
61
249
2.49
9.87
2.0
2.2
1.04
0.89
%
1.26
52
170
32
91
3.55
9.77
1.7
5.0
—
—
—
0
0
18
17
10.66
9.77
1.6
1.1
—
—
—
0
0
224
1440
1.61
9.68
4.8
4.2
92.12
86.60
ng/l
0.28
198
1286
424
3128
1.43
9.50
2.2
2.2
28.91
29.50
s
1.68
411
3047
20
25
8.06
9.33
2.2
2.1
—
—
—
0
0
280
1919
1.52
9.12
2.1
2.0
0.00
0.02
estimate
1.06
78
427
42
150
2.83
8.86
2.0
2.6
446.30
576.56
e6/l
0.83
30
125
645
5181
1.33
8.43
3.0
3.2
1546.11
1069.06
ng/l
1.22
540
4361
43
160
2.72
8.42
1.2
1.1
—
—
—
0
0
21
49
4.31
8.40
1.2
1.2
12.83
7.13
pmol/l
0.84
14
16
375
2782
1.41
8.07
1.3
1.3
—
—
—
0
0
103
564
1.86
7.94
1.9
3.8
43.92
68.68
mg/l
0.59
83
475
82
416
2.00
7.92
4.4
4.1
2.11
2.38
mmol/l
0.41
56
266
82
416
2.00
7.92
4.4
4.1
9.04
8.84
kpa
0.37
82
408
24
65
3.72
7.90
1.4
1.3
—
—
—
0
0
82
417
2.00
7.87
4.4
4.1
4.96
5.02
kpa
0.27
82
410
806
6726
1.29
7.87
1.6
1.5
—
—
—
0
0
186
1209
1.58
7.69
1.8
2.5
—
—
—
0
0
267
1876
1.47
7.69
9.1
8.4
1.27
1.34
mmol/l
0.52
260
1839
112
638
1.79
7.62
3.7
4.3
1.39
1.41
mmol/l
0.06
106
630
102
565
1.84
7.60
1.9
3.8
57.77
59.72
mg/l
0.06
84
476
141
858
1.68
7.59
1.3
1.2
—
—
—
0
0
120
704
1.74
7.39
1.4
2.4
4.45
4.23
g/l
2.45
113
653
120
704
1.74
7.39
1.4
2.4
3.95
3.71
g/l
0.80
113
654
68
331
2.08
7.37
2.0
1.4
62.74
64.40
mmol/l
0.09
42
274
89
478
1.89
7.31
1.9
2.5
0.96
0.89
nmol/l
0.30
78
415
63
300
2.13
7.23
1.4
1.5
—
—
—
0
0
63
300
2.13
7.23
1.4
1.5
—
—
—
0
0
63
300
2.13
7.23
1.4
1.5
—
—
—
0
0
63
300
2.13
7.23
1.4
1.5
—
—
—
0
0
24
70
3.45
7.11
1.3
2.3
28.00
30.30
%
0.34
24
70
156
992
1.61
7.09
2.2
2.1
0.00
0.78
estimate
0.51
58
329
106
612
1.76
6.92
2.2
2.3
11.63
11.13
mg/l
0.25
97
575
110
647
1.73
6.74
1.3
1.2
6.07
2.43
u/ml
—
8
55
143
902
1.62
6.73
6.1
3.8
—
—
—
0
0
537
4323
1.31
6.71
1.4
1.3
22.15
27.27
iu/ml
0.42
176
1276
138
868
1.62
6.57
1.9
1.8
—
—
—
0
0
110
652
1.72
6.56
1.3
1.3
6.45
8.40
u/ml
0.25
17
94
94
533
1.79
6.54
1.3
1.2
35.64
47.24
u/ml
—
8
50
32
118
2.73
6.44
6.3
3.4
0.91
0.81
index
0.11
32
118
35
137
2.58
6.28
2.6
2.1
1.40
1.76
u/field
0.32
25
84
38
155
2.47
6.27
2.0
2.7
209.57
226.51
e6/l
0.17
28
134
104
616
1.72
6.24
1.1
1.1
1.66
4.72
eliau/ml
—
10
86
664
5547
1.27
6.15
3.1
2.6
343.91
339.31
umol/l
0.56
618
4994
754
6397
1.26
6.11
4.9
4.2
8.06
8.76
mg/mmol
0.19
519
4103
235
1687
1.43
6.06
3.7
2.3
6.00
6.09
ph
0.86
173
1099
479
3850
1.30
6.00
3.9
3.6
258.58
484.84
ng/l
1.97
307
2716
50
235
2.15
5.99
2.7
2.7
—
—
—
0
0
172
1166
1.51
5.93
2.1
2.3
4370.19
5565.65
u/l
0.20
56
459
88
505
1.77
5.91
1.8
3.6
2.04
3.43
ratio
0.62
53
273
190
1318
1.48
5.86
3.7
2.9
253.44
172.00
ng/l
1.00
177
1190
34
138
2.48
5.70
2.7
2.5
642.56
616.65
ml
0.11
25
96
1584
14626
1.23
5.54
4.0
3.7
0.50
15260.85
—
6
27
10
10
10.03
5.53
1.3
1.1
—
—
—
0
0
172
1187
1.48
5.46
1.6
1.8
0.33
0.31
mg/l
0.15
75
591
24
83
2.91
5.46
1.0
1.0
—
—
—
0
0
735
6315
1.23
5.16
3.7
3.6
50.91
51.03
mg/l
0.01
518
4148
23
81
2.86
5.08
1.0
1.1
—
—
—
0
0
99
614
1.64
5.06
1.4
2.5
10.60
10.31
g/l
0.23
92
561
69
388
1.80
5.01
1.1
1.1
59.30
1492.23
iu/ml
—
8
90
1806
16981
1.23
4.95
4.4
4.3
14.74
14.59
pmol/l
1.77
1692
15844
409
3327
1.27
4.60
1.5
1.5
—
—
—
0
0
48
248
1.95
4.55
2.1
2.3
31.10
32.59
pg
1.10
48
248
43
216
2.01
4.41
2.4
5.8
6.59
7.11
mmol/l
0.56
33
180
22
84
2.63
4.23
1.1
5.6
10521.50
79.78
mg/l
0.48
16
67
105
694
1.54
4.16
3.1
3.5
242.12
371.33
mg/l
0.75
57
329
85
538
1.60
4.07
1.1
1.1
—
—
—
0
0
2079
19967
1.24
4.01
5.4
5.1
1.73
1.83
mu/l
4.15
1964
18785
56
318
1.78
4.01
2.3
2.5
17.63
36.69
iu/ml
—
7
32
28
124
2.27
3.96
2.2
3.2
1148.21
1017.27
u/ml
0.12
28
124
222
2859
0.75
3.89
1.3
1.3
—
—
—
0
0
812
7205
1.19
3.87
3.7
3.5
8.50
8.14
mmol/l
1.21
717
6258
39
200
1.97
3.82
1.7
1.6
45.32
57.38
%
0.88
22
124
84
539
1.58
3.82
1.1
1.1
—
—
—
0
0
32
629
0.50
3.80
1.5
1.5
1.36
1.26
mm
0.62
24
435
135
959
1.43
3.77
1.4
1.3
203.34
225.98
miu/ml
0.26
56
457
49
276
1.79
3.63
1.4
1.2
—
—
—
0
0
31
150
2.08
3.57
1.2
1.1
340.75
397.22
nmol/l
0.92
24
138
30
144
2.10
3.53
1.0
1.4
4.88
6.09
u/l
1.27
25
122
34
637
0.53
3.50
1.6
1.5
—
—
—
0
0
182
2368
0.75
3.44
1.6
1.7
3.48
3.50
mmol/l
0.11
122
1601
36
656
0.54
3.39
1.6
1.5
—
—
—
0
0
171
1294
1.35
3.31
12.0
11.2
0.64
0.64
%
0.05
165
1286
40
219
1.84
3.28
1.0
1.1
—
—
—
0
0
33
173
1.92
3.09
1.1
1.1
99.82
107.92
pmol/l
0.54
33
173
13
41
3.18
3.05
1.2
1.0
—
—
—
0
0
97
678
1.45
3.02
1.1
1.1
—
—
—
0
0
173
1331
1.32
3.01
11.7
10.9
1.22
1.36
%
1.58
166
1324
437
3749
1.20
2.96
3.2
2.8
2.44
2.43
mmol/l
0.66
385
3379
17
69
2.47
2.96
1.5
2.0
0.23
0.17
e9/l
—
5
31
29
149
1.96
2.90
1.0
1.0
—
—
—
0
0
21
95
2.22
2.89
1.6
3.1
91.20
127.67
umol/l
—
10
52
58
367
1.59
2.87
1.7
1.6
—
—
—
0
0
5
6
8.35
2.75
1.0
1.0
178.40
263.33
u/ml
—
5
6
23
112
2.06
2.67
1.0
1.1
—
—
—
0
0
20
92
2.18
2.67
1.2
1.1
—
—
—
0
0
82
1156
0.70
2.63
1.1
1.1
1.50
1.51
g/l
0.22
82
1156
24
120
2.01
2.60
2.0
1.2
26.99
35.79
mmol/l
1.64
24
115
54
822
0.65
2.57
1.4
1.5
66.41
59.52
ug/l
0.59
45
679
562
5002
1.16
2.44
4.2
3.5
0.13
0.18
0.17
15
38
98
721
1.37
2.35
1.9
2.3
393.33
295.98
ug/l
0.34
86
685
265
3145
0.82
2.33
1.8
1.9
3.65
3.57
ratio
0.37
201
2386
59
396
1.50
2.32
2.1
1.9
—
—
—
0
0
26
141
1.85
2.27
1.1
1.2
8.81
8.98
mm/h
0.03
26
141
197
1608
1.24
2.22
2.4
2.5
26.30
21.45
au/ml
0.22
15
201
347
3996
0.85
2.19
3.0
3.0
0.68
0.72
ug/l
0.50
235
2366
1955
18935
1.15
2.17
36.1
17.3
332.12
333.43
g/l
7.91
1948
18828
45
290
1.56
2.14
1.6
1.4
98.03
49.35
mu/l
0.94
40
262
60
413
1.46
2.11
3.7
3.5
28.31
25.72
mg/l
0.22
50
281
11
43
2.56
2.08
1.0
1.1
—
—
—
0
0
29
168
1.73
2.07
1.9
1.4
39.39
33.90
%
0.29
18
105
81
1090
0.73
2.02
1.1
1.1
0.68
0.66
ratio
—
10
114
8
26
3.08
2.01
1.3
1.8
—
—
—
0
0
21
112
1.88
1.96
1.9
1.3
—
—
—
0
0
53
364
1.47
1.91
1.1
1.1
1.10
2.43
eliau/ml
2.99
19
175
41
268
1.54
1.87
3.8
2.5
—
—
—
0
0
220
1855
1.20
1.85
1.2
1.2
—
—
—
0
0
19
101
1.89
1.80
1.8
1.6
—
—
—
0
0
7
23
3.05
1.80
1.1
1.2
—
—
—
0
0
112
1414
0.78
1.79
1.7
1.6
—
—
—
0
0
8
29
2.76
1.79
1.0
1.0
—
—
—
0
0
111
872
1.29
1.77
1.9
2.3
21.70
20.84
s
0.45
100
777
60
432
1.40
1.71
2.8
2.4
49.21
133.22
ug/min
2.28
39
273
23
133
1.74
1.70
1.3
1.4
144.41
137.73
nmol/l
0.24
23
133
27
164
1.65
1.68
5.7
3.0
41.42
42.75
mg/l
0.02
21
123
38
252
1.52
1.65
1.1
1.4
—
—
nmol/l
—
0
0
13
62
2.10
1.65
2.2
1.8
42.12
40.84
g/l
0.37
13
62
32
204
1.58
1.65
1.3
1.3
0.25
1.54
u/ml
1.50
14
108
179
1499
1.21
1.64
1.3
1.3
50.73
48.10
au/ml
—
6
103
12
57
2.11
1.55
1.5
1.7
—
—
—
0
0
13
64
2.04
1.54
1.0
1.1
0.46
1.78
u/ml
—
5
35
126
1538
0.81
1.53
1.3
1.3
—
—
—
0
0
26
162
1.61
1.49
2.3
1.4
101.42
77.15
umol/l
0.76
26
162
27
170
1.59
1.49
1.1
1.3
—
—
—
0
0
38
259
1.47
1.48
1.1
1.4
0.19
0.24
nmol/l
0.36
27
207
23
139
1.66
1.48
1.1
1.2
—
—
—
0
0
17
94
1.81
1.47
1.2
1.1
—
—
—
0
0
5
16
3.13
1.44
1.0
1.6
198.40
344.19
umol/24h
—
5
16
7
152
0.46
1.43
1.4
1.4
49.01
34.60
nmol/l
—
7
131
11
212
0.52
1.40
13.5
21.4
1196.91
1440.53
nmol/l
0.38
11
207
13
67
1.95
1.38
1.2
1.1
—
—
—
0
0
32
463
0.69
1.31
1.4
1.6
—
—
—
0
0
20
121
1.66
1.30
1.1
1.2
—
—
—
0
0
278
3123
0.88
1.30
1.7
1.8
—
—
—
0
0
27
179
1.51
1.23
1.3
1.3
34213.00
93627.60
e6/l
0.75
17
118
175
1511
1.17
1.20
1.4
1.4
25.75
24.10
iu/l
0.27
161
1277
6
26
2.31
1.18
1.0
1.1
0.01
0.02
u/ml
—
6
26
60
463
1.30
1.18
1.1
1.1
46.40
17.33
au/ml
0.99
20
129
5
20
2.50
1.15
1.0
1.1
—
—
—
0
0
122
1441
0.84
1.12
1.5
1.6
1081.27
1035.50
mu/l
0.20
101
1189
25
168
1.49
1.09
1.0
1.0
0.82
2.17
u/ml
—
7
54
17
262
0.65
1.00
1.9
1.5
—
—
—
0
0
5
109
0.46
1.00
7.2
6.5
16.20
8.65
%
—
5
109
5
109
0.46
1.00
3.6
3.2
26.20
44.83
%
—
5
109
64
511
1.26
1.00
1.7
1.6
16347.94
13280.93
e6/l
0.26
54
354
9
48
1.88
1.00
2.6
1.9
—
—
—
0
0
38
282
1.35
1.00
2.2
3.4
0.80
0.81
nmol/l
0.03
27
227
261
2353
1.12
0.99
4.3
4.5
31.99
31.43
%
0.35
201
1659
7
37
1.89
0.94
1.4
2.0
—
—
—
0
0
6
27
2.23
0.93
6.0
5.8
10.40
8.47
mmol/l
—
6
27
29
209
1.39
0.92
1.1
1.4
199.32
206.97
pmol/l
0.05
29
209
49
384
1.28
0.91
1.1
1.2
—
—
—
0
0
51
640
0.79
0.89
1.5
3.2
—
—
—
0
0
16
103
1.56
0.87
1.3
1.3
131.69
164.51
mmol/24h
0.93
16
103
26
186
1.40
0.87
1.2
1.1
—
—
—
0
0
8
44
1.82
0.85
1.0
1.3
—
—
—
0
0
8
44
1.82
0.85
1.0
1.3
—
—
—
0
0
8
44
1.82
0.85
1.0
1.3
—
—
—
0
0
27
367
0.73
0.85
1.3
1.2
—
—
—
0
0
8
45
1.78
0.84
1.8
2.8
—
—
—
0
0
25
179
1.40
0.84
1.4
2.4
—
—
—
0
0
78
654
1.20
0.81
14.4
8.8
—
—
—
0
0
24
172
1.40
0.81
1.1
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
26
190
1.37
0.79
1.3
1.2
—
—
—
0
0
16
106
1.51
0.79
2.1
2.6
1870.00
2153.58
ml
0.64
16
98
0
26
0.00
0.78
0.0
1.2
—
—
—
0
0
15
98
1.53
0.78
2.1
1.8
—
—
—
0
0
163
1461
1.12
0.73
3.6
3.6
4.62
4.58
pmol/l
0.15
148
1326
43
345
1.25
0.70
1.7
1.9
—
1378.46
—
0
13
48
585
0.82
0.69
1.1
1.1
2.41
1.57
u/ml
0.29
25
291
1979
20055
0.94
0.66
6.9
5.7
39.28
38.49
mmol/mol
3.30
1881
19088
103
1171
0.87
0.66
1.4
2.4
—
—
—
0
0
50
412
1.22
0.66
1.3
1.4
23.60
21.79
u/l
0.18
45
342
20
146
1.37
0.63
2.0
3.1
37.40
42.86
%
—
10
74
101
1145
0.88
0.63
1.7
1.7
317.23
284.38
mu/l
0.44
94
1049
105
927
1.14
0.62
1.4
1.4
8.89
8.89
u/l
0.00
89
754
167
1518
1.11
0.61
2.6
2.2
5.63
7.82
ug/l
1.18
156
1385
0
20
0.00
0.60
0.0
1.5
—
35.16
—
0
20
0
22
0.00
0.59
0.0
2.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
15.56
—
0
9
888
9171
0.95
0.59
2.1
1.9
1.41
1.39
mmol/l
0.23
762
7938
31
246
1.26
0.58
1.1
1.1
—
—
—
0
0
52
613
0.85
0.56
1.1
1.1
7.41
5.27
u/ml
0.35
23
344
125
1383
0.90
0.54
1.4
2.4
—
—
—
0
0
12
82
1.47
0.54
4.6
2.5
—
—
—
0
0
11
74
1.49
0.53
2.5
1.3
—
—
—
0
0
38
313
1.22
0.53
1.4
1.7
—
—
—
0
0
22
169
1.30
0.53
1.1
1.1
—
—
—
0
0
9
62
1.45
0.53
2.4
1.3
9.39
10.33
mmol/l
—
9
62
10
66
1.52
0.52
1.0
1.1
—
—
—
0
0
10
66
1.52
0.52
1.0
1.1
—
—
—
0
0
10
66
1.52
0.52
1.0
1.1
—
—
—
0
0
21
161
1.31
0.51
1.2
1.0
—
—
—
0
0
6
40
1.50
0.51
1.3
1.4
—
—
—
0
0
15
109
1.38
0.51
1.7
1.9
80.49
106.44
ng/l
0.72
15
109
38
455
0.83
0.50
1.0
1.0
0.19
0.25
u/ml
0.15
11
144
94
1048
0.89
0.49
1.5
3.4
—
—
—
0
0
2058
20376
1.06
0.48
4.8
4.6
5.89
5.85
mmol/l
0.62
1939
19054
7
46
1.52
0.48
6.3
6.1
6.41
5.45
kpa
—
7
46
15
111
1.35
0.46
1.4
2.5
14.37
16.54
%
1.20
15
111
135
1471
0.91
0.46
1.3
2.3
—
—
—
0
0
13
96
1.36
0.41
1.2
1.1
10.29
279.00
ng/l
—
7
20
0
16
0.00
0.41
0.0
1.1
—
0.19
—
0
6
14
105
1.34
0.41
1.2
1.1
150.77
187.42
iu/ml
0.40
14
105
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.0
3.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
0.15
—
0
8
7
103
0.68
0.39
3.6
1.7
—
—
—
0
0
138
1488
0.92
0.39
1.3
2.2
—
—
—
0
0
10
71
1.41
0.39
4.2
2.7
—
—
—
0
0
16
124
1.29
0.38
1.8
2.3
9.09
8.16
mmol/l
0.29
16
124
139
1496
0.92
0.38
1.4
2.3
—
—
—
0
0
97
888
1.10
0.36
1.7
1.7
12.50
13.34
u/ml
0.04
14
238
147
1372
1.08
0.36
1.1
1.1
—
—
—
0
0
5
76
0.66
0.35
1.4
1.7
0.00
0.08
estimate
—
5
76
99
910
1.09
0.35
2.5
2.3
—
—
—
0
0
31
264
1.18
0.34
2.3
2.3
—
—
—
0
0
22
181
1.22
0.34
1.2
1.1
—
—
—
0
0
52
584
0.89
0.34
1.1
1.1
0.44
1.36
u/ml
1.43
18
255
6
45
1.33
0.33
1.0
1.1
—
—
—
0
0
2158
21716
0.95
0.33
5.5
5.2
2.68
2.78
mmol/l
6.58
2053
20581
11
144
0.76
0.33
1.6
3.5
—
—
—
0
0
6
86
0.70
0.33
1.5
1.7
—
—
—
0
0
139
1484
0.93
0.32
1.3
2.3
—
—
—
0
0
42
476
0.88
0.32
1.0
1.1
7.04
4.68
u/ml
0.24
18
213
13
165
0.79
0.32
1.3
1.5
—
—
—
0
0
185
1753
1.06
0.31
1.2
1.2
95.16
139.38
u/ml
1.01
75
659
21
175
1.20
0.30
3.1
3.5
53.54
24.99
mu/l
1.12
15
168
61
671
0.91
0.29
1.1
1.1
1.13
2.34
u/ml
0.71
23
350
57
516
1.11
0.29
1.6
1.4
—
—
—
0
0
8
63
1.27
0.27
1.4
1.1
—
—
—
0
0
13
161
0.81
0.27
1.4
1.4
—
—
—
0
0
8
66
1.21
0.26
2.1
2.4
—
—
—
0
0
20
169
1.18
0.25
1.1
1.1
0.41
1.99
u/ml
—
6
38
9
73
1.23
0.25
1.1
1.4
—
—
—
0
0
5
38
1.32
0.23
1.0
1.0
3.22
6.78
u/ml
—
5
38
225
2336
0.96
0.22
2.5
2.4
13.23
13.48
nmol/l
0.19
208
2158
19
221
0.86
0.22
5.7
5.5
15.38
79.45
u/ml
—
10
69
5
41
1.22
0.22
1.0
1.4
—
191.33
—
0
6
19
163
1.17
0.21
1.4
1.9
7.03
6.71
mmol/l
0.19
13
114
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
3.2
—
104.25
—
0
12
0
12
0.00
0.21
0.0
2.2
—
368.08
—
0
12
15
126
1.19
0.21
1.0
1.0
307.60
257.83
ng/l
—
10
89
42
383
1.10
0.20
1.1
1.3
5.96
4.73
u/ml
0.30
25
179
0
14
0.00
0.20
0.0
1.1
—
0.13
—
0
7
25
221
1.13
0.20
1.2
1.2
40.30
42.48
mg/l
0.09
20
182
2132
21407
0.97
0.18
5.1
4.6
1.43
1.43
mmol/l
0.10
2024
20269
25
223
1.12
0.18
1.2
1.4
—
—
—
0
0
7
60
1.17
0.17
1.7
2.1
—
—
—
0
0
21
187
1.12
0.15
2.3
2.8
—
—
—
0
0
40
371
1.08
0.15
1.1
1.2
—
—
—
0
0
23
207
1.11
0.15
1.0
1.1
15.53
16.34
u/ml
—
10
87
64
607
1.06
0.13
1.1
1.1
—
—
—
0
0
969
9598
1.02
0.13
3.6
2.9
—
—
—
0
0
13
149
0.87
0.13
1.0
1.1
—
4.34
—
0
29
9
109
0.83
0.13
1.7
1.5
0.49
0.49
e9/l
—
9
109
12
137
0.88
0.12
6.8
7.4
1.17
140.36
ug/l
—
6
95
70
670
1.05
0.11
2.9
2.6
—
—
—
0
0
44
416
1.06
0.11
1.3
1.2
—
—
—
0
0
651
6572
0.99
0.09
4.9
4.8
4.47
2.13
ug/l
0.84
606
5988
19
207
0.92
0.09
1.0
1.1
—
—
—
0
0
10
87
1.15
0.09
1.2
1.6
105.50
172.00
nmol/24h
—
10
87
19
174
1.09
0.09
1.3
1.3
0.62
0.58
ratio
0.13
11
102
8
94
0.85
0.06
1.0
1.1
—
—
—
0
0
26
274
0.95
0.06
1.7
1.4
—
—
—
0
0
64
656
0.97
0.05
2.6
2.2
3.14
12.02
iu/l
0.55
34
282
62
605
1.03
0.04
1.4
1.3
—
—
—
0
0
2037
20345
1.01
0.03
4.5
4.0
1.32
1.30
mmol/l
0.56
1922
19129
23
220
1.05
0.03
2.9
2.6
0.68
1.61
g/24h
1.64
17
141
18
171
1.05
0.03
1.2
1.1
—
—
—
0
0
29
281
1.03
0.02
2.1
2.3
—
—
—
0
0
49
500
0.98
0.02
1.5
1.5
0.37
0.42
nmol/l
0.23
40
392
16
168
0.95
0.02
1.3
1.4
—
—
—
0
0
57
560
1.02
0.02
1.6
1.4
1655.10
1372.92
e6/l
0.09
52
440
2152
21504
1.01
0.02
5.3
4.7
4.59
4.68
mmol/l
4.72
2050
20477
56
552
1.01
0.01
1.5
1.4
44.98
36.75
e6/l
0.10
47
410
48
473
1.02
0.01
1.3
1.3
—
—
—
0
0
83
823
1.01
0.01
1.9
1.9
—
—
—
0
0
15
149
1.01
0.00
1.0
1.1
—
—
—
0
0
51
507
1.01
0.00
1.1
1.1
4.69
3.40
u/ml
0.20
25
255
0
9
0.00
0.00
0.0
1.4
—
444.72
—
0
9
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1500.83
—
0
6
6
66
0.91
-0.00
2.3
3.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
1067.57
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
-0.00
1.1
1.2
—
0.06
—
0
7
8
82
0.98
-0.00
1.4
1.2
25.50
28.38
s
—
8
82
0
6
0.00
-0.00
0.0
7.7
—
—
—
0
0
6
66
0.91
-0.00
1.2
1.2
40.00
51.53
%
—
6
59
0
5
0.00
-0.00
0.0
1.0
—
2800.00
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
173.00
—
0
6
0
7
0.00
-0.00
0.0
3.1
—
2.04
—
0
7

Mortality – FinRegistry

Association

Association between endpoint ULCEROTH and mortality.

Females

Parameter HR [95% CI] p-value
ULCEROTH 1.372 [1.22, 1.55] < 0.001
Birth year 1.001 [0.99, 1.01] 0.903

During the follow-up period (1.1.1998 — 31.12.2019), 567 out of 5349 females with ULCEROTH died.

Males

Parameter HR [95% CI] p-value
ULCEROTH 1.247 [1.12, 1.39] < 0.001
Birth year 0.989 [0.98, 1.0] 0.025

During the follow-up period (1.1.1998 — 31.12.2019), 815 out of 5965 males with ULCEROTH died.

Mortality risk

Mortality risk for people of age

years, who have ULCEROTH.

N-year risk Females Males
1 0.097% 0.224%
5 0.749% 1.434%
10 2.112% 3.919%
15 4.287% 7.111%
20 7.497% 12.132%

Relationships between endpoints

Index endpoint: ULCEROTH – Other ulcerative colitis

GWS hits: 10

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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