Unequal limb length (acquired)

M13_LIMBLENGTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M21.7
  • Cause of death: ICD-10 M21.7

2 out of 7 registries used, show all original rules.

393

4. Check minimum number of events

None

393

5. Include endpoints

None

393

6. Filter based on genotype QC (FinnGen only)

363

Control definitions (FinnGen only)

Control exclude
M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M21
Name in latin
Inaequalitas hongitudinis membrorum (acquisita)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5169 2272 2894
Only index persons 4933 2151 2782
Unadjusted period prevalence (%)
Whole population 0.07 0.07 0.08
Only index persons 0.09 0.08 0.11
Median age at first event (years)
Whole population 13.10 12.57 13.51
Only index persons 13.24 12.74 13.63

-FinnGen-

Key figures

All Female Male
Number of individuals 363 219 144
Unadjusted period prevalence (%) 0.07 0.08 0.07
Median age at first event (years) 14.32 14.13 14.62

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
372
Matched controls
3720
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M21.7
ICD-10 Finland
Unequal limb length (acquired)
+∞
307.7
372
*
NFK20
NOMESCO Finland
Epiphysiodesis of femur
165.8
42.8
44
*
NGK20
NOMESCO Finland
Epiphysiodesis of knee or lower leg
405.9
37.7
37
*
NF1AA
NOMESCO Finland
Hip X-ray examination
12.3
35.9
37
33
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
381.4
35.6
35
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
7.7
34.0
51
75
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
8.5
28.2
38
49
M16.1
ICD-10 Finland
Other primary coxarthrosis
38.4
28.0
35
10
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
10.2
27.5
32
34
M25.5
ICD-10 Finland
Pain in joint
3.5
26.1
116
422
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
6.0
23.0
43
79
M17.1
ICD-10 Finland
Other primary gonarthrosis
19.6
22.6
34
19
N03AX12
ATC
[U] gabapentin; oral
4.6
22.3
58
143
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
21.0
20
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
8.0
20.7
29
39
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
15.8
19.8
32
22
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
29.6
19.0
25
9
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
105.4
18.7
20
*
NK6JD
NOMESCO Finland
Ortopaedic measurement of extemities with CT
+∞
17.9
17
*
ZXA00
NOMESCO Finland
Right side
3.2
16.7
77
280
M70.6
ICD-10 Finland
Trochanteric bursitis
4.5
16.4
43
106
N02AX02
ATC
tramadol; systemic, rectal
2.7
16.0
119
559
L13
ICPC
Hip symptom/complaint
3.4
15.3
61
202
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
59.2
14.9
17
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.4
14.9
39
96
NE1AA
NOMESCO Finland
Pelvis X-ray examination
6.9
14.6
23
35
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
17.9
14.5
22
13
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
44.3
14.2
17
*
M19.0
ICD-10 Finland
Primary arthrosis of other joints
15.5
13.7
22
15
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
19.9
13.0
19
10
L04AX03
ATC
methotrexate; systemic
5.8
12.3
23
42
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.5
12.0
92
432
N02BF01
ATC
gabapentin; oral
3.8
11.9
38
108
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.1
11.6
25
52
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
123.7
11.5
12
*
B01AB05
ATC
enoxaparin; parenteral
2.6
11.4
78
347
M13.9
ICD-10 Finland
Arthritis, unspecified
11.7
11.2
20
18
N03AX16
ATC
[U] pregabalin
2.8
10.8
60
239
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.9
10.8
33
91
WX320
NOMESCO Finland
Spinalanesthesy
2.7
10.7
64
266
ZXA05
NOMESCO Finland
Left side
2.8
10.6
60
242
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.1
10.5
48
172
Q72.88
ICD-10 Finland
Other reduction defects of lower himb(s)
+∞
10.5
10
*
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
16.6
10.4
16
10
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
7.8
10.3
23
31
S82.2
ICD-10 Finland
Fracture of shaft of tibia
9.1
9.9
20
23
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
5.5
9.7
19
36
M01AC06
ATC
meloxicam; systemic, rectal
2.4
9.7
78
372
M79.6
ICD-10 Finland
Pain in limb
2.0
9.6
142
863
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
+∞
9.4
9
*
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
+∞
9.4
9
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.1
9.3
117
668
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.7
9.3
30
86
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.6
9.2
22
50
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
5.0
9.2
20
42
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
11.9
9.2
16
14
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.7
9.0
53
217
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
19.2
9.0
13
7
SPAT1229
SPAT
Assessment of need for aid
4.6
8.7
21
48
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.5
8.6
60
267
M41.8
ICD-10 Finland
Other forms of scoliosis
28.2
8.5
11
*
NF1DA
NOMESCO Finland
X-ray of hips
28.2
8.5
11
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.5
8.5
21
49
M54.4
ICD-10 Finland
Lumbago with sciatica
2.4
8.4
63
290
NGU20
NOMESCO Finland
Removal of internal fixation device from knee or lower leg
11.1
8.4
15
14
M41.9
ICD-10 Finland
Scoliosis, unspecified
11.1
8.4
15
14
NJ3MA
NOMESCO Finland
Measurement of extremity length with X-ray
+∞
8.4
8
*
M21.0
ICD-10 Finland
Valgus deformity, not elsewhere classified
+∞
8.4
8
*
S43.4
ICD-10 Finland
Sprain and strain of shoulder joint
4.4
8.3
21
50
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
34.2
8.1
10
*
H02AB06
ATC
prednisolone; systemic
2.0
8.1
127
780
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
8.0
89
482
Z3226
NOMESCO Finland
Physiotherapist
2.4
8.0
63
296
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
8.0
8.0
17
22
B01AF01
ATC
rivaroxaban; oral
3.8
7.9
24
66
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.0
7.8
35
124
S72.3
ICD-10 Finland
Fracture of shaft of femur
15.4
7.8
12
8
M22.0
ICD-10 Finland
Recurrent dislocation of patella
46.0
7.7
9
*
L01BA01
ATC
methotrexate; systemic
25.6
7.6
10
*
A02BC02
ATC
pantoprazole; systemic
1.8
7.5
186
1314
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
7.5
119
730
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
7.9
7.5
16
21
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
7.4
183
1291
N06AX21
ATC
duloxetine; oral
2.6
7.4
43
175
NGK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of knee or lower leg
+∞
7.3
7
*
M16.3
ICD-10 Finland
Other dysplastic coxarthrosis
+∞
7.3
7
*
NFK60
NOMESCO Finland
Lengthening osteotomy of femur
+∞
7.3
7
*
NFK50
NOMESCO Finland
Shortening osteotomy of femur
+∞
7.3
7
*
M01AX05
ATC
glucosamine; oral
3.6
7.2
24
70
SPAT1153
SPAT
Removal of sutures
2.1
7.2
81
439
M01AX17
ATC
nimesulide; oral
2.7
7.2
41
165
L28
ICPC
Limited function/disability (L)
2.5
7.2
47
203
M53.3
ICD-10 Finland
Sacrococcygeal disorders, not elsewhere classified
12.3
7.1
12
10
WX212
NOMESCO Finland
Femoral plexus blockade
12.3
7.1
12
10
M01AB55
ATC
diclofenac, combinations; oral
7.2
7.1
16
23
M43.1
ICD-10 Finland
Spondylolisthesis
6.5
7.0
17
27
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
6.9
79
431
N06AA09
ATC
amitriptyline; systemic
3.8
6.8
21
58
NFK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of femur
40.8
6.8
8
*
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
3.1
6.7
28
95
M01AH01
ATC
celecoxib; oral
2.9
6.7
31
112
M01AH05
ATC
etoricoxib; oral
1.8
6.6
167
1174
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
12.5
6.6
11
9
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
12.5
6.6
11
9
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
6.6
68
357
M24.4
ICD-10 Finland
Recurrent dislocation and subluxation of joint
71.0
6.4
7
*
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.7
6.4
20
56
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.8
6.4
31
115
9165
FHL
Removal of osteosynthesis material
9.5
6.3
12
13
M54.5
ICD-10 Finland
Low back pain
1.8
6.3
124
809
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
+∞
6.3
6
*
Z01.2
ICD-10 Finland
Dental examination
1.7
6.3
209
1582
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
27.2
6.3
8
*
NG1DA
NOMESCO Finland
X-ray of knees
27.2
6.3
8
*
R52.2
ICD-10 Finland
Other chronic pain
5.9
6.2
16
28
R4110, ,
SPAT
2.5
6.2
40
172
A03FA02
ATC
cisapride; oral, rectal
3.2
6.2
24
78
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
6.2
136
916
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
12.8
6.1
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
138
858
1.97
8.57
2.2
2.2
—
—
—
0
0
139
879
1.93
8.13
6.9
6.2
—
—
—
0
0
201
1504
1.73
6.28
7.2
6.2
0.18
0.18
e9/l
0.10
186
1316
178
1299
1.71
6.01
3.0
2.7
—
—
estimate
—
0
0
9
6
15.32
5.93
2.1
1.0
—
—
—
0
0
193
1443
1.70
5.93
7.3
5.8
0.04
0.04
e9/l
0.77
176
1243
193
1444
1.70
5.91
7.2
5.8
0.56
0.53
e9/l
0.80
176
1244
181
1333
1.70
5.86
7.5
6.0
0.64
0.65
%
0.13
172
1255
200
1514
1.69
5.83
7.1
5.8
1.91
2.08
e9/l
1.17
190
1348
181
1335
1.69
5.81
7.4
5.9
2.84
2.75
%
0.25
173
1260
180
1340
1.67
5.48
7.5
6.0
8.60
8.41
%
0.43
172
1269
63
347
1.98
5.31
1.4
1.1
10.24
1.34
u/ml
0.54
28
129
138
966
1.68
5.27
4.8
4.7
37.97
37.65
g/l
0.31
131
919
184
1390
1.64
5.20
7.2
5.7
54.94
55.58
%
0.37
178
1338
236
1909
1.65
4.99
8.5
6.4
80.17
78.25
u/l
0.24
221
1795
185
1412
1.62
4.93
7.4
5.8
30.53
30.43
%
0.05
179
1350
208
1634
1.62
4.92
9.0
8.8
3.75
3.97
e9/l
0.84
185
1413
58
320
1.96
4.86
1.2
1.3
700.00
470.59
titre
—
8
51
158
1181
1.59
4.47
3.1
2.4
74.79
71.47
nmol/l
0.88
148
1096
127
905
1.61
4.37
6.9
7.9
1.07
1.12
inr
0.96
98
769
89
582
1.70
4.27
2.3
2.0
0.63
1.12
mg/l
2.38
69
399
196
1557
1.55
4.15
4.6
5.1
6.12
6.30
mmol/l
0.58
182
1406
103
706
1.63
4.11
4.6
4.1
—
—
—
0
0
136
1002
1.56
4.00
7.0
7.1
1.22
1.22
mmol/l
0.22
130
924
162
1243
1.54
3.96
5.7
6.1
10.37
10.67
umol/l
0.19
147
1170
51
289
1.89
3.94
2.4
2.0
—
—
—
0
0
38
194
2.07
3.94
4.4
5.4
0.31
0.72
%
0.93
13
58
110
775
1.60
3.90
3.0
2.8
17.56
43.13
ng/l
1.60
61
403
112
794
1.59
3.87
2.8
2.5
—
—
—
0
0
84
556
1.66
3.82
3.1
3.6
25.33
62.48
mg/l
2.02
50
382
133
988
1.54
3.72
1.9
1.8
—
—
—
0
0
149
1135
1.52
3.71
7.6
7.0
1.22
1.22
mmol/l
0.27
130
985
84
565
1.63
3.58
3.8
4.3
3.33
10.13
mg/mmol
2.57
48
384
62
390
1.71
3.40
1.5
1.1
19.54
13.36
iu/ml
0.61
14
90
37
201
1.93
3.26
5.0
5.6
0.00
0.15
%
1.71
11
55
114
840
1.51
3.24
3.3
3.2
7.35
8.92
mmol/l
2.91
98
743
38
209
1.91
3.23
5.4
5.9
0.00
0.20
%
—
10
55
50
301
1.76
3.20
2.6
2.9
3.74
4.95
e9/l
0.92
45
279
19
79
2.48
3.19
1.3
3.6
—
—
—
0
0
37
207
1.87
3.00
4.9
11.4
—
—
—
0
0
5
5
10.11
2.98
2.8
1.8
32.20
24.40
%
—
5
5
5
5
10.11
2.98
2.8
1.8
9.00
4.80
%
—
5
5
341
3174
1.89
2.97
11.4
8.1
28.03
25.90
u/l
1.04
334
3082
12
38
3.23
2.87
4.8
2.2
1.52
2.71
mmol/l
—
6
23
37
210
1.85
2.87
5.0
5.6
0.55
1.18
%
0.92
11
64
49
303
1.71
2.86
1.2
1.7
—
—
—
0
0
20
90
2.29
2.85
1.1
1.1
—
—
—
0
0
276
2454
1.48
2.79
4.7
4.4
36.78
36.83
mmol/mol
0.04
264
2329
88
638
1.50
2.66
2.8
2.6
—
—
—
0
0
45
278
1.70
2.64
1.2
1.2
—
—
—
0
0
96
710
1.47
2.62
2.4
2.1
2.44
2.50
mg/l
0.12
83
608
9
25
3.66
2.59
1.7
1.6
1.44
1.80
mmol/l
—
9
25
103
775
1.46
2.58
3.0
2.3
50.29
63.61
u/l
1.44
95
715
5
7
7.22
2.55
2.8
2.6
—
—
—
0
0
5
7
7.22
2.55
2.8
2.6
—
—
—
0
0
43
268
1.68
2.46
4.3
8.7
105.51
104.68
mmol/l
0.62
43
268
11
38
2.95
2.43
3.9
2.9
2.97
3.44
e9/l
0.37
11
38
7
17
4.18
2.37
1.3
2.1
11.57
10.13
umol/l
—
7
17
24
126
1.97
2.37
6.1
4.7
—
—
—
0
0
21
106
2.04
2.30
6.7
4.8
24.57
24.49
mmol/l
0.06
21
106
69
491
1.50
2.27
2.8
2.4
558.15
551.93
mosm/kgh2o
0.08
62
429
16
73
2.25
2.24
1.2
1.5
974.36
400.98
mu/l
0.37
11
56
88
659
1.44
2.24
5.3
3.4
7.39
7.39
ph
0.52
59
451
11
41
2.73
2.22
6.6
2.6
—
—
—
0
0
336
3162
1.65
2.16
16.8
11.7
70.62
71.00
umol/l
0.14
329
3116
6
14
4.34
2.16
2.7
2.0
134.17
204.00
e6/l
—
6
14
38
239
1.66
2.12
2.2
5.5
1.64
1.64
mmol/l
0.00
32
198
305
2816
1.46
2.10
5.8
4.8
1.82
1.84
mu/l
0.15
292
2646
7
20
3.55
2.06
1.9
1.6
93.00
92.02
%
—
7
20
53
365
1.53
2.04
2.5
2.2
13.65
14.90
umol/l
0.63
48
339
362
3492
2.36
2.01
21.3
15.6
261.58
257.39
e9/l
0.66
357
3413
38
244
1.62
1.96
2.2
5.7
7.37
7.37
ph
0.26
21
144
10
39
2.61
1.95
3.4
3.2
6.14
7.69
pmol/l
—
10
39
6
16
3.79
1.94
1.2
1.3
72.83
76.13
umol/l
—
6
16
32
197
1.68
1.94
1.7
1.6
8.34
13.98
iu/l
1.61
27
153
362
3497
2.31
1.91
21.3
15.6
4.57
4.61
e12/l
0.93
357
3418
81
615
1.41
1.90
1.7
1.5
19.38
19.81
nmol/l
0.11
68
533
362
3498
2.30
1.89
21.3
15.6
6.78
6.69
e9/l
0.35
357
3411
32
199
1.67
1.87
4.8
11.0
1.07
1.32
mmol/l
1.76
32
193
11
46
2.43
1.87
2.0
2.5
—
—
—
0
0
73
546
1.42
1.86
4.2
3.7
—
—
—
0
0
29
176
1.70
1.86
1.4
1.2
—
—
—
0
0
192
1670
1.31
1.82
3.5
3.0
95.54
74.65
ug/l
0.90
178
1577
64
473
1.43
1.74
3.6
2.8
340.42
327.10
umol/l
0.42
57
435
39
262
1.55
1.69
1.7
1.4
—
—
—
0
0
5
14
3.60
1.62
1.8
1.5
9.80
10.57
mmol/l
—
5
14
12
57
2.14
1.56
1.8
2.5
4.57
4.56
index
—
7
29
38
259
1.52
1.56
4.5
2.9
—
—
—
0
0
124
1034
1.30
1.56
3.6
3.3
10.17
85.75
e6/l
4.81
81
654
102
828
1.32
1.56
3.3
2.7
12.82
57.27
e6/l
3.17
77
608
89
709
1.34
1.54
3.2
2.6
0.15
0.29
e6/l
1.26
64
491
128
1073
1.29
1.54
1.9
1.8
1.35
1.31
mmol/l
0.18
104
940
304
2852
1.36
1.50
15.0
11.4
3.92
3.91
mmol/l
0.23
295
2764
56
417
1.40
1.47
1.6
1.6
471.53
71268026.23
pmol/l
1.02
43
355
44
315
1.45
1.43
1.9
1.5
—
—
—
0
0
303
2847
1.35
1.43
15.0
11.3
139.44
139.62
mmol/l
0.69
295
2766
336
3212
1.48
1.42
12.9
9.1
—
—
—
0
0
29
191
1.56
1.39
11.1
8.5
5.83
6.69
mmol/l
0.79
29
186
16
90
1.81
1.35
1.2
1.2
—
—
—
0
0
22
138
1.63
1.29
2.0
1.6
39.59
37.32
nmol/l
0.17
22
132
6
25
2.42
1.25
2.2
2.0
33.67
31.64
pg
—
6
25
69
547
1.32
1.24
3.1
2.3
5.25
8.35
e6/l
1.41
61
488
294
2768
1.30
1.24
4.1
3.6
1.40
1.44
mmol/l
0.93
283
2637
14
78
1.83
1.23
1.1
1.3
—
—
—
0
0
40
291
1.42
1.22
1.7
1.6
1079.44
1178.99
nmol/l
0.28
31
222
5
19
2.65
1.22
3.0
3.3
—
—
—
0
0
18
109
1.68
1.21
1.7
5.4
0.69
0.61
%
0.47
18
109
132
1140
1.24
1.21
1.7
1.8
—
—
—
0
0
262
2437
1.25
1.19
5.0
4.1
14.59
14.56
pmol/l
0.08
243
2230
25
167
1.53
1.15
5.4
13.4
122.88
125.41
g/l
0.21
25
161
54
418
1.34
1.15
3.1
3.6
298.72
712.77
ng/l
0.59
39
248
296
2799
1.28
1.13
4.6
4.0
2.76
2.74
mmol/l
0.10
286
2665
294
2783
1.27
1.08
4.2
3.6
4.61
4.60
mmol/l
0.08
285
2663
64
514
1.30
1.06
3.9
2.7
106.11
103.05
ug/g
0.04
51
397
141
1242
1.22
1.05
3.7
2.9
6.26
6.27
ph
0.04
80
681
155
1379
1.21
1.04
12.0
8.6
0.00
0.00
e9/l
0.20
131
1109
13
75
1.76
1.04
9.7
8.6
—
—
—
0
0
174
1568
1.21
1.02
4.4
3.2
0.00
0.02
estimate
0.79
43
316
173
1559
1.21
1.01
4.3
3.1
0.00
4.75
estimate
0.50
43
317
278
2624
1.24
0.99
4.0
3.5
5.62
5.60
mmol/l
0.10
261
2444
171
1542
1.20
0.99
4.2
3.1
0.00
0.00
estimate
-0.00
42
325
5
23
2.19
0.98
1.8
6.8
—
—
—
0
0
0
31
0.00
0.97
0.0
1.3
—
41.11
—
0
21
51
404
1.30
0.94
1.9
2.5
2.42
2.42
mmol/l
0.04
46
362
17
253
0.66
0.91
1.1
1.4
36.40
265.35
miu/ml
—
5
128
64
771
0.79
0.91
1.5
1.6
—
—
—
0
0
47
372
1.30
0.88
1.3
1.5
3.61
3.43
mmol/l
0.38
30
237
95
819
1.21
0.87
4.4
3.1
0.00
0.01
estimate
0.80
43
310
272
2576
1.21
0.86
3.5
3.1
1.27
1.18
mmol/l
1.45
265
2447
27
197
1.40
0.85
2.6
2.8
0.23
0.23
g/l
0.22
27
184
111
975
1.20
0.83
2.1
1.7
98.93
95.94
pmol/l
0.35
54
512
6
32
1.89
0.82
1.7
1.2
—
—
—
0
0
6
32
1.89
0.82
2.7
2.2
1163.50
1372.08
e6/l
—
6
24
33
427
0.75
0.82
1.2
1.3
—
—
—
0
0
16
106
1.53
0.80
1.8
1.5
0.26
0.41
nmol/l
—
9
90
11
66
1.69
0.79
4.2
2.6
49.00
55.30
%
0.68
11
66
131
1173
1.18
0.79
4.2
2.9
0.00
0.03
estimate
1.34
41
271
0
27
0.00
0.77
0.0
1.3
—
0.62
—
0
14
37
289
1.31
0.77
1.4
1.2
—
—
—
0
0
316
3048
1.24
0.77
14.8
10.2
20.23
22.34
mg/l
0.54
268
2310
24
175
1.40
0.77
6.6
14.3
97.01
95.67
%
1.09
24
168
97
849
1.19
0.76
1.7
1.4
2.23
1.98
g/l
0.69
67
531
8
132
0.60
0.75
1.0
1.1
0.80
2.52
u/ml
—
8
75
14
92
1.54
0.73
3.4
4.4
92.50
323.86
mg/l
—
8
49
95
833
1.19
0.73
6.5
5.3
—
—
—
0
0
47
384
1.26
0.71
2.1
2.0
—
—
—
0
0
15
101
1.51
0.71
6.7
18.4
15.43
16.34
%
0.56
15
94
5
26
1.94
0.71
3.0
2.0
40.00
39.30
%
—
5
26
46
376
1.25
0.69
4.7
4.3
1.40
1.88
ug/l
1.00
41
341
5
27
1.86
0.68
1.0
1.3
—
—
—
0
0
13
87
1.51
0.64
1.2
1.1
—
—
—
0
0
13
87
1.51
0.64
1.2
1.1
—
—
—
0
0
21
156
1.37
0.62
1.3
1.5
—
—
—
0
0
8
51
1.58
0.61
1.4
1.7
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
20
152
1.33
0.53
5.5
3.0
—
—
—
0
0
48
408
1.20
0.53
2.4
2.5
4.41
3.39
e6/l
0.25
22
189
14
102
1.39
0.48
2.1
2.3
2.10
4.60
iu/l
—
8
46
10
141
0.70
0.45
1.6
1.4
—
—
—
0
0
36
303
1.21
0.45
1.4
1.3
89.79
132.49
u/ml
0.60
15
116
14
104
1.36
0.43
1.6
1.4
218.33
194.83
u/ml
—
6
59
26
212
1.24
0.43
6.6
12.1
4.88
5.06
kpa
0.55
26
200
26
212
1.24
0.43
6.5
12.1
14.30
13.28
kpa
0.33
26
202
26
212
1.24
0.43
6.6
12.2
7.42
7.42
ph
—
10
122
6
95
0.63
0.42
1.0
1.1
5.71
7.32
u/ml
—
6
48
5
32
1.57
0.42
1.0
1.2
207.52
198.31
pmol/l
—
5
32
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
3.2
—
104.65
—
0
17
0
17
0.00
0.40
0.0
3.2
—
1.19
—
0
17
0
17
0.00
0.40
0.0
3.2
—
4.01
—
0
17
80
726
1.13
0.40
4.5
3.1
1.02
1.02
kg/l
0.62
50
462
5
34
1.48
0.40
2.0
2.8
—
—
—
0
0
132
1235
1.11
0.39
2.5
2.4
—
—
—
0
0
25
208
1.22
0.36
3.1
1.8
5.89
6.31
ph
1.80
19
128
6
41
1.47
0.36
1.2
1.6
16.53
59.63
ng/l
—
6
41
14
108
1.31
0.36
12.7
8.0
1.08
1.14
mg/l
0.20
14
103
35
304
1.17
0.33
2.3
2.8
—
—
—
0
0
40
453
0.87
0.33
2.7
2.1
—
—
—
0
0
12
93
1.30
0.30
1.8
2.0
—
—
—
0
0
29
334
0.86
0.30
1.4
1.2
—
—
—
0
0
40
449
0.88
0.29
2.6
2.0
—
—
—
0
0
27
232
1.18
0.29
1.5
1.4
—
—
—
0
0
40
448
0.88
0.29
2.6
2.0
—
—
—
0
0
105
988
1.09
0.28
1.5
1.4
1.84
1.83
u/ml
0.00
36
259
13
104
1.26
0.27
1.3
1.2
—
—
—
0
0
99
933
1.08
0.25
3.3
2.5
0.00
0.02
estimate
0.69
43
260
279
2845
0.92
0.25
16.6
13.0
333.93
334.24
g/l
0.23
279
2819
6
83
0.72
0.24
1.0
1.2
—
—
—
0
0
10
125
0.79
0.23
1.9
2.8
27.60
46.53
u/ml
—
10
118
5
39
1.29
0.23
4.8
2.1
—
—
—
0
0
5
42
1.19
0.21
2.2
2.5
1.28
1.21
mmol/l
—
5
37
5
42
1.19
0.21
1.6
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
61.82
—
0
11
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
5.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
5.82
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
15
126
1.20
0.21
2.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
21145.00
—
0
8
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
41
447
0.91
0.20
2.6
2.1
—
—
—
0
0
7
60
1.17
0.18
1.1
1.0
—
—
—
0
0
7
60
1.17
0.18
1.7
13.9
1.09
1.11
mmol/l
—
7
52
8
71
1.13
0.16
1.0
1.0
—
—
—
0
0
16
182
0.87
0.15
1.3
1.3
—
—
—
0
0
224
2198
1.05
0.15
3.2
2.8
34.12
32.19
u/l
0.23
214
2115
27
246
1.11
0.15
2.0
2.0
—
—
—
0
0
14
122
1.15
0.14
2.4
2.5
5.01
7.10
ug/l
0.33
14
101
20
221
0.90
0.13
1.5
1.5
—
—
—
0
0
20
221
0.90
0.13
1.6
1.6
—
—
—
0
0
39
416
0.93
0.13
2.6
2.1
—
—
—
0
0
60
629
0.95
0.12
1.4
1.7
—
—
—
0
0
32
298
1.08
0.12
5.3
3.1
4.70
7.38
umol/l
1.17
26
262
37
347
1.07
0.12
2.6
2.6
7972.75
4502.51
u/l
0.20
13
152
6
54
1.11
0.09
1.2
1.1
—
—
—
0
0
6
54
1.11
0.09
1.5
1.4
—
—
—
0
0
6
55
1.09
0.09
1.3
1.5
0.48
0.50
e9/l
—
6
55
32
303
1.06
0.08
1.3
1.4
—
—
—
0
0
6
73
0.82
0.07
1.2
1.0
—
—
—
0
0
33
347
0.95
0.07
2.9
2.2
—
—
—
0
0
20
214
0.93
0.07
3.4
2.6
0.75
0.76
ug/l
0.03
12
114
8
91
0.88
0.07
1.1
1.1
—
—
—
0
0
92
902
1.03
0.05
3.5
2.5
—
0.00
—
0
6
13
141
0.92
0.05
4.0
4.8
2.14
7.63
ug/l
—
8
119
18
169
1.07
0.05
1.2
1.1
0.91
0.88
g/l
0.28
18
169
19
179
1.06
0.05
1.3
1.5
—
—
—
0
0
97
954
1.02
0.04
1.6
2.0
—
—
—
0
0
23
219
1.05
0.04
1.3
1.1
—
60.17
titre
—
0
6
12
111
1.08
0.04
3.9
8.3
—
—
—
0
0
40
409
0.98
0.02
1.3
1.7
—
—
—
0
0
15
157
0.95
0.01
1.2
1.1
—
—
—
0
0
19
197
0.96
0.01
1.3
1.2
—
—
—
0
0
103
1038
0.99
0.01
1.7
1.9
—
—
—
0
0
11
116
0.95
0.00
5.2
9.8
23.74
24.21
mmol/l
0.29
11
108
15
156
0.96
0.00
1.1
1.2
—
25.60
—
0
11
17
168
1.01
0.00
1.1
1.1
1.39
1.51
g/l
1.38
17
168
10
99
1.01
0.00
1.8
1.4
—
—
—
0
0
18
179
1.01
0.00
4.3
2.8
—
—
—
0
0
133
1325
1.01
0.00
2.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
86
0.93
-0.00
1.3
1.4
—
—
—
0
0
6
67
0.89
-0.00
1.2
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
-0.00
2.1
11.6
0.71
0.98
%
—
7
59
0
9
0.00
-0.00
0.0
1.2
—
19.49
—
0
9
0
9
0.00
-0.00
0.0
1.0
—
5.68
—
0
9
8
83
0.96
-0.00
2.4
9.9
1.29
1.60
%
—
8
71
0
6
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.3
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
68
0.88
-0.00
2.8
2.7
—
24.36
—
0
5
0
6
0.00
-0.00
0.0
13.2
—
0.55
—
0
6
0
8
0.00
-0.00
0.0
1.9
—
90.56
—
0
8
0
8
0.00
-0.00
0.0
3.6
—
126.50
—
0
8
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
6
60
1.00
-0.00
2.8
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
8
81
0.99
-0.00
2.5
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_LIMBLENGTH and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_LIMBLENGTH.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: M13_LIMBLENGTH – Unequal limb length (acquired)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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