microscopic colitis: Inflammation of the colon that is only apparent by microscopic examination.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
231 |
4. Check minimum number of eventsNone |
231 |
5. Include endpointsNone |
231 |
6. Filter based on genotype QC (FinnGen only) |
211 |
Control definitions (FinnGen only)
- Control exclude
- M13_NECROVASC
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M31
Similar endpoints
↥List of similar endpoints to
Microscopic polyangiitis
based on the number of shared cases.
Similar with more cases:
- Other necrotizing vasculopathies (FG)
- Other necrotizing vasculopathies
- Systemic connective tissue disorders
- Autoimmune diseases related-to ILD
- Autoimmune diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 813 | 470 | 342 |
| Only index persons | 808 | 467 | 341 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 68.31 | 67.54 | 69.40 |
| Only index persons | 68.35 | 67.57 | 69.42 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 211 | 119 | 92 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 67.20 | 65.23 | 69.75 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 216
- Matched controls
- 2160
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M31.7
ICD-10 Finland
Microscopic polyangiitis
+∞
210.3
166
*
L04AX01
ATC
azathioprine; systemic
83.1
207.8
120
32
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
161.4
134
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
52.7
102.4
61
16
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
202.0
95.1
93
8
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
15.6
94.7
117
152
L04AA06
ATC
mycophenolic acid; systemic
46.9
91.6
56
16
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
42.7
90.7
57
18
N17.9
ICD-10 Finland
Acute renal failure, unspecified
19.5
66.4
57
39
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
14.2
62.3
66
65
A11CC03
ATC
alfacalcidol; systemic
31.4
60.2
41
16
B03XA02
ATC
darbepoetin alfa; parenteral
27.2
58.5
42
19
TK800
NOMESCO Finland
Hemodialysis
25.1
55.3
41
20
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
12.3
54.5
63
70
N18.8
ICD-10 Finland
Other chronic renal failure
25.4
51.8
38
18
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
45.4
42
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
8.0
43.9
166
634
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
10.3
43.5
56
71
H02AB06
ATC
prednisolone; systemic
9.7
41.0
184
806
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
40.9
38
*
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
39.8
37
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
8.3
37.7
59
94
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.4
35.5
78
176
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
8.5
34.9
52
78
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
34.3
32
*
TGC00
NOMESCO Finland
Bronchial lavation
11.8
32.7
36
36
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
59.3
30.4
35
7
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.8
29.7
180
913
M05BA04
ATC
alendronic acid; oral
6.5
29.5
58
116
Z49.1
ICD-10 Finland
Extracorporeal dialysis
46.0
29.1
35
9
H02AB04
ATC
methylprednisolone; systemic
5.4
29.1
77
202
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
9.6
28.2
36
44
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.5
27.2
115
433
C03CA01
ATC
furosemide; systemic
4.4
25.8
125
515
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
+∞
25.5
24
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.0
24.9
52
109
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.7
24.1
43
77
ZX120
NOMESCO Finland
Intravenous
5.4
23.7
56
131
GD1AD
NOMESCO Finland
Thorax CT examination
6.3
23.4
45
87
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.9
23.3
65
175
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
6.9
23.2
40
69
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
9.0
22.7
30
38
ZX108
NOMESCO Finland
Inhalation
41.9
21.3
26
7
N18.0
ICD-10 Finland
End-stage renal disease
53.7
20.6
24
5
N085, M318,
ICD-10 Finland
+∞
19.0
18
*
N19
ICD-10 Finland
Unspecified kidney failure
6.9
18.7
31
51
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
8.3
17.3
24
32
A12AA04
ATC
calcium carbonate; oral
24.4
17.3
24
11
J01MA14
ATC
moxifloxacin; systemic
4.7
16.8
45
115
Z94.0
ICD-10 Finland
Kidney transplant status
43.9
16.6
20
5
KA1AE
NOMESCO Finland
Kidney ultrasound examination
15.4
16.0
26
19
R50.9
ICD-10 Finland
Fever, unspecified
3.7
15.5
63
218
Z49.0
ICD-10 Finland
Preparatory care for dialysis
31.3
15.5
20
7
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
25.7
15.4
21
9
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
25.7
15.4
21
9
WW400
NOMESCO Finland
Plasmaferesis
+∞
14.7
14
*
N17.8
ICD-10 Finland
Other acute renal failure
24.3
14.5
20
9
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.8
14.5
52
165
D64.9
ICD-10 Finland
Anaemia, unspecified
3.9
14.4
50
155
A02BC02
ATC
pantoprazole; systemic
4.4
14.2
186
1268
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.5
14.0
29
59
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
57.3
14.0
16
*
N08.5*M31.0
ICD-10 Finland
Glomerular disorders in Goodpasture's syndrome
+∞
13.7
13
*
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
+∞
13.7
13
*
A10AC01
ATC
insulin (human); parenteral
4.4
13.4
38
101
127
Kela drug reimbursment
Transplant complication
18.2
13.3
20
12
3025
Kela drug reimbursment
Calcium carbonate
53.4
13.0
15
*
N08.5*M30.0
ICD-10 Finland
Glomerular disorders in polyarteritis nodosa
+∞
12.6
12
*
C08CA01
ATC
amlodipine; oral
2.8
12.5
126
717
137
Kela drug reimbursment
Uraemia requiring dialysis
40.1
12.4
15
*
205
Kela drug reimbursment
Chronic hypertension
2.9
12.3
86
404
L04AD02
ATC
tacrolimus; systemic
28.6
12.2
16
6
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
22.9
12.2
17
8
Z49.2
ICD-10 Finland
Other dialysis
49.6
12.0
14
*
J01MA12
ATC
levofloxacin; systemic
3.0
12.0
67
278
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
68.8
11.7
13
*
JN4AD
NOMESCO Finland
Body CT examination
3.4
11.7
50
176
L01AA01
ATC
cyclophosphamide; systemic
45.8
11.0
13
*
R04.2
ICD-10 Finland
Haemoptysis
5.7
10.8
21
40
B05DB
ATC
Hypertonic solutions
63.2
10.7
12
*
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
8.9
10.6
22
27
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
10.5
10
*
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
24.8
10.4
14
6
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
10.2
63
273
R31
ICD-10 Finland
Unspecified haematuria
3.4
10.2
42
144
B05DA
ATC
Isotonic solutions
42.2
10.1
12
*
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
17.8
10.0
15
9
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
5.1
10.0
22
47
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
10.0
73
345
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.5
9.9
38
124
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
9.8
9.7
19
21
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
57.7
9.7
11
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.5
9.5
19
37
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
9.4
9
*
M30.0
ICD-10 Finland
Polyarteritis nodosa
+∞
9.4
9
*
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
+∞
9.4
9
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.4
9.2
111
659
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.9
9.2
29
83
V03AE02
ATC
sevelamer; oral
38.4
9.1
11
*
C10AA05
ATC
atorvastatin; oral
2.4
8.9
124
780
PAW37
NOMESCO Finland
Biopsy of temporal artery
52.2
8.7
10
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.6
8.6
31
97
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
21.1
8.6
12
6
B01AF02
ATC
apixaban; oral
2.8
8.6
50
209
JN3AD
NOMESCO Finland
Abdominal CT examination
2.9
8.5
45
178
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
93.6
8.5
9
*
C02AC05
ATC
moxonidine; oral
4.5
8.4
21
50
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
8.4
8
*
1AA01, ,
NOMESCO Finland
+∞
8.4
8
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.0
8.3
40
150
R05
ICD-10 Finland
Cough
2.5
8.2
63
301
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
34.8
8.1
10
*
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
34.8
8.1
10
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.0
8.0
24
66
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.8
7.9
44
179
TK820
NOMESCO Finland
Peritoneal dialysis
46.7
7.8
9
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.2
7.7
33
115
J47
ICD-10 Finland
Bronchiectasis
7.8
7.3
16
22
N05.9
ICD-10 Finland
Unspecified nephritic syndrome, unspecified
+∞
7.3
7
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
7.3
77
422
B03XA01
ATC
erythropoietin; parenteral
16.5
7.3
11
7
TK810
NOMESCO Finland
Hemofiltration
20.9
7.2
10
5
R4190
NOMESCO Finland
Nutritional therapy
4.1
7.2
20
52
H03AA01
ATC
levothyroxine sodium; systemic
2.3
6.9
63
324
J01CA04
ATC
amoxicillin; systemic
2.9
6.9
188
1507
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.1
6.8
31
112
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.5
6.8
24
74
3AC01, ,
NOMESCO Finland
23.4
6.7
9
*
C08CA02
ATC
felodipine; oral
3.0
6.7
31
113
D638, N188,
ICD-10 Finland
71.9
6.5
7
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
27.6
6.3
8
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
27.6
6.3
8
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
27.6
6.3
8
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.7
6.2
20
58
J01AA02
ATC
doxycycline; systemic
2.5
6.1
178
1416
M13.9
ICD-10 Finland
Arthritis, unspecified
3.1
6.1
27
96
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
105
33
60.97
172.47
4.0
1.1
246.67
—
titre
—
12
0
83
102
12.59
67.79
2.5
2.3
1.70
1.52
g/l
0.67
78
90
56
46
16.08
58.83
6.6
8.3
485.31
168.50
iu/ml
—
13
6
70
84
11.85
57.50
2.6
1.5
6.74
8.25
iu/ml
0.18
23
17
62
65
12.98
55.84
1.7
1.6
5.56
0.08
iu/ml
—
6
12
158
500
9.04
53.99
12.5
2.7
2.03
4.97
e6/l
4.68
152
450
190
769
13.22
49.37
22.2
3.5
—
—
—
0
0
179
714
9.80
45.90
18.0
3.5
51.16
132.36
e6/l
0.42
170
548
89
196
7.02
42.28
1.7
2.8
62.82
66.56
g/l
3.50
79
181
55
78
9.12
38.86
1.3
4.5
78.41
129.96
mg/l
0.29
48
64
55
78
9.12
38.86
1.3
4.5
61.58
34.81
mg/l
3.78
48
65
52
70
9.47
38.29
1.3
4.1
1.41
3.73
ratio
0.96
31
33
168
711
7.13
37.61
19.9
4.2
26.29
8.56
mg/mmol
3.29
157
445
54
87
7.94
33.98
2.5
1.9
1.33
4.51
ug/l
0.47
47
76
76
179
6.01
32.78
9.7
2.4
0.09
0.65
e6/l
0.61
76
172
37
39
11.24
32.45
1.9
1.8
—
—
—
0
0
42
54
9.41
31.81
1.5
1.6
—
—
—
0
0
198
1094
10.72
29.72
30.6
8.0
1.21
1.21
mmol/l
0.33
180
936
42
59
8.60
29.54
2.0
1.8
—
—
—
0
0
51
90
7.11
29.29
1.2
2.3
35.14
38.81
u/l
0.56
46
82
145
629
4.97
28.83
18.4
3.4
0.20
0.53
e6/l
2.17
135
461
38
49
9.20
28.60
1.5
1.6
—
—
—
0
0
35
41
9.99
28.34
5.9
3.4
10.27
9.90
pmol/l
0.05
35
41
133
547
4.73
28.19
6.0
3.1
387.98
345.34
umol/l
4.31
127
464
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
43
68
7.65
27.22
3.8
3.2
0.41
0.38
iu/ml
0.12
26
38
32
35
10.56
27.19
2.3
1.6
111.65
135.37
au/ml
—
6
12
33
38
10.07
27.02
1.6
1.4
—
—
—
0
0
202
1186
11.85
26.96
23.6
10.5
4.88
4.06
e9/l
5.70
191
1034
40
59
8.09
26.90
2.0
1.7
—
—
—
0
0
35
44
9.30
26.81
1.6
1.7
—
—
—
0
0
108
392
4.51
26.76
2.9
2.0
—
—
—
0
0
128
532
4.45
26.25
2.7
2.2
2.76
3.03
mg/l
0.74
115
456
39
58
7.99
26.01
1.3
1.8
—
—
—
0
0
59
136
5.59
25.53
11.8
3.9
0.87
1.86
mmol/l
1.42
47
105
37
53
8.22
25.46
1.4
1.3
—
—
—
0
0
31
38
9.36
24.13
1.6
1.7
—
—
—
0
0
30
36
9.52
23.72
1.7
1.4
222.95
335.18
u/ml
0.49
22
17
88
297
4.31
23.56
2.4
1.9
—
—
—
0
0
186
1083
6.17
22.96
13.4
3.8
0.00
0.00
estimate
-0.00
50
258
28
32
9.90
22.94
1.9
1.4
—
—
—
0
0
186
1095
6.03
22.31
13.6
3.9
0.00
6.17
estimate
0.50
50
263
186
1105
5.92
21.78
13.6
3.9
0.00
0.00
estimate
-0.00
49
239
27
32
9.50
21.49
2.1
1.4
—
—
—
0
0
99
389
3.85
20.94
13.8
3.2
0.39
1.04
e6/l
3.33
78
204
79
280
3.87
19.20
2.5
2.0
—
—
—
0
0
33
57
6.65
19.01
1.5
1.4
3.90
8.84
u/ml
—
10
13
58
169
4.32
18.45
3.8
2.9
44.81
60.57
ml/min/173m2
2.98
32
76
31
52
6.79
18.34
2.3
1.2
—
—
—
0
0
17
0
+∞
17.96
1.2
0.0
—
—
—
0
0
198
1333
6.82
17.45
11.8
4.9
236.50
185.43
e6/l
—
6
23
38
86
5.15
16.41
3.3
2.9
—
—
—
0
0
86
355
3.36
16.11
15.5
3.4
1.02
2.27
e6/l
1.54
65
171
40
99
4.73
15.51
1.4
2.0
8.16
7.52
g/l
1.18
34
90
40
99
4.73
15.51
1.4
2.0
3.91
4.26
g/l
1.32
34
90
40
99
4.73
15.51
1.4
2.0
3.76
3.99
g/l
0.25
34
90
127
680
3.11
14.93
2.5
2.2
157.45
173.82
u/l
0.16
121
645
25
20
13.97
14.81
2.3
3.6
1182.96
756.00
mg
0.71
25
20
104
504
3.05
14.51
3.7
2.7
—
—
—
0
0
27
27
11.26
14.45
1.7
1.7
—
—
—
0
0
22
37
6.51
12.87
1.4
1.6
—
—
—
0
0
22
37
6.51
12.87
1.4
1.6
—
—
—
0
0
33
81
4.63
12.84
6.7
2.5
23.18
24.80
mmol/l
1.86
33
81
118
645
2.83
12.73
2.3
1.7
20.55
21.25
nmol/l
0.17
109
526
35
91
4.40
12.67
1.4
2.0
11.10
10.71
g/l
0.22
28
81
35
92
4.35
12.48
1.5
2.0
3.57
3.11
g/l
1.22
29
83
94
460
2.85
12.48
2.3
1.9
3.16
1.60
mg/l
1.37
85
370
44
140
3.69
12.05
2.6
1.7
—
—
—
0
0
156
1010
2.96
11.80
13.1
13.5
1.17
1.24
inr
1.00
142
831
74
334
2.85
11.25
7.1
7.6
103.73
104.06
mmol/l
0.21
74
334
19
16
12.89
11.08
1.7
1.4
—
—
—
0
0
26
60
4.79
10.85
1.4
1.3
—
—
—
0
0
78
368
2.75
10.84
2.1
1.7
1106.78
1206.05
nmol/l
0.42
67
272
173
1214
3.14
10.74
10.7
6.2
6.81
6.71
mmol/l
0.16
168
1158
146
939
2.71
10.72
4.3
3.1
—
—
estimate
—
0
0
111
633
2.55
10.37
13.8
4.0
0.00
0.00
estimate
-0.00
48
236
31
88
3.95
9.92
1.5
2.4
0.08
0.50
g/l
1.20
24
74
21
27
8.49
9.89
1.1
1.0
—
—
—
0
0
72
347
2.61
9.40
1.5
1.3
92.15
37.42
iu/ml
0.96
22
111
38
130
3.33
9.22
6.5
2.6
0.68
0.64
%
0.27
38
130
43
160
3.11
9.08
1.8
1.6
—
—
—
0
0
66
312
2.61
8.91
1.5
1.3
19.56
12.06
u/ml
0.27
29
109
28
80
3.87
8.86
3.1
1.9
—
—
—
0
0
121
763
2.33
8.51
5.7
3.4
2.32
2.36
mmol/l
2.32
115
686
15
14
11.41
8.43
1.8
1.4
—
—
—
0
0
16
18
9.50
8.19
2.2
1.4
—
—
—
0
0
12
7
18.03
8.17
2.1
2.0
0.61
0.61
mmol/l
—
12
7
15
15
10.65
8.17
1.8
1.3
—
—
—
0
0
26
75
3.80
8.11
3.0
1.8
—
—
—
0
0
136
918
2.30
7.92
2.8
2.2
101.32
95.95
pmol/l
0.56
82
453
18
27
7.17
7.77
1.4
1.2
38.57
1.38
u/ml
—
7
8
57
272
2.49
7.41
6.3
10.9
4.91
5.19
kpa
1.93
57
264
21
56
4.05
7.27
1.5
1.4
291.73
271.91
ug/g
0.12
11
32
15
19
8.39
7.24
2.1
2.2
—
—
—
0
0
18
43
4.48
7.16
2.4
2.5
535.16
62.42
ug/min
1.33
12
26
21
57
3.97
7.10
3.5
2.4
119.46
125.81
g/l
0.42
13
42
111
716
2.13
6.91
4.1
3.4
2276.25
1151.31
ng/l
2.11
102
599
55
267
2.42
6.84
6.5
11.1
-0.08
1.07
mmol/l
1.30
48
232
49
226
2.51
6.80
4.2
3.5
—
—
—
0
0
18
45
4.27
6.77
1.7
1.3
—
40.80
—
0
5
17
29
6.27
6.76
1.4
1.2
3.38
5.09
u/ml
—
8
11
31
113
3.04
6.72
1.3
1.4
—
35.81
—
0
9
29
102
3.13
6.67
1.4
1.4
—
—
—
0
0
15
22
7.24
6.64
2.1
2.0
—
—
—
0
0
10
7
14.89
6.46
1.1
1.0
—
—
—
0
0
9
5
18.69
6.32
1.1
3.4
—
—
—
0
0
6
0
+∞
6.28
1.5
0.0
—
—
—
0
0
11
12
9.59
5.86
2.8
1.4
—
—
—
0
0
41
187
2.47
5.78
12.0
4.1
1.22
1.23
mmol/l
0.67
41
164
144
1066
2.05
5.76
3.4
2.7
—
—
—
0
0
15
28
5.67
5.65
1.2
1.2
—
—
—
0
0
14
25
5.91
5.47
1.2
1.4
—
—
—
0
0
14
25
5.91
5.47
1.7
1.4
—
—
—
0
0
99
655
1.94
5.36
5.0
2.6
82.66
68.87
u/l
0.33
94
603
10
11
9.46
5.34
1.2
1.4
—
—
—
0
0
5
0
+∞
5.23
1.8
0.0
—
—
—
0
0
20
65
3.29
5.22
1.5
1.3
—
—
—
0
0
115
815
1.88
4.93
6.2
4.2
44.19
38.48
ng/l
0.35
102
622
204
1786
3.56
4.91
50.7
18.2
53.15
77.52
ml/min/173m2
25.23
196
1672
16
48
3.52
4.70
1.4
1.3
—
—
—
0
0
114
814
1.85
4.69
14.1
3.7
0.00
0.00
estimate
0.50
46
209
9
11
8.48
4.60
2.2
1.4
99.71
72.59
ng/l
—
9
11
9
11
8.48
4.60
1.0
1.0
1722.78
1480.82
miu/ml
—
9
11
7
5
14.40
4.60
1.1
2.0
—
—
—
0
0
7
5
14.40
4.60
1.0
1.0
101.86
104.00
%
—
7
5
10
16
6.49
4.34
6.9
2.6
—
—
—
0
0
19
69
2.92
4.14
1.4
1.2
—
—
—
0
0
11
22
5.21
4.06
1.7
1.4
—
—
—
0
0
11
22
5.21
4.06
1.7
1.4
—
—
—
0
0
11
22
5.21
4.06
1.7
1.4
—
—
—
0
0
11
22
5.21
4.06
1.7
1.4
—
—
—
0
0
153
1229
1.84
3.99
4.1
3.4
52.78
50.65
u/l
0.11
148
1141
16
54
3.12
3.94
1.2
1.2
—
—
—
0
0
11
23
4.98
3.93
1.7
1.3
—
—
—
0
0
11
23
4.98
3.93
1.7
1.3
—
—
—
0
0
13
33
4.12
3.87
1.2
1.2
—
—
—
0
0
17
61
2.94
3.78
1.8
1.6
—
—
—
0
0
6
5
12.29
3.78
1.0
1.0
—
—
—
0
0
15
50
3.15
3.77
1.3
1.5
4521.90
15110.50
e6/l
—
10
36
12
29
4.32
3.76
1.0
1.0
—
11.24
—
0
7
11
25
4.58
3.67
1.0
1.2
—
—
—
0
0
12
30
4.17
3.65
1.0
1.2
—
—
—
0
0
173
1464
1.91
3.58
5.3
4.4
15.49
14.86
pmol/l
2.42
165
1315
11
26
4.40
3.56
1.0
1.3
—
—
—
0
0
11
26
4.40
3.56
1.0
1.3
—
—
—
0
0
65
420
1.78
3.52
2.0
1.8
448.20
448.01
pmol/l
0.00
56
350
86
602
1.71
3.52
12.8
3.1
0.00
0.00
estimate
0.50
45
209
8
14
5.89
3.37
1.3
1.9
—
—
—
0
0
8
14
5.89
3.37
1.3
1.9
—
—
—
0
0
6
7
8.77
3.28
1.8
2.9
—
—
—
0
0
6
7
8.77
3.28
1.8
2.9
—
—
—
0
0
6
7
8.77
3.28
1.8
2.9
—
—
—
0
0
6
7
8.77
3.28
1.8
2.9
—
—
—
0
0
11
29
3.94
3.23
1.0
1.2
—
—
—
0
0
7
11
6.53
3.21
1.3
1.2
—
—
—
0
0
10
25
4.14
3.12
1.0
1.3
—
—
—
0
0
196
1756
2.25
3.11
6.5
4.6
1.33
1.26
mmol/l
0.99
189
1588
6
8
7.67
3.07
1.3
1.3
438.17
106.88
iu/ml
—
6
8
5
5
10.19
2.99
1.0
1.2
—
—
—
0
0
11
32
3.57
2.94
7.0
3.5
—
—
—
0
0
6
9
6.82
2.88
1.2
1.1
—
—
—
0
0
6
9
6.82
2.88
1.2
1.1
—
—
—
0
0
6
9
6.82
2.88
1.5
1.2
56.00
76.67
u/l
—
6
9
6
9
6.82
2.88
1.5
1.2
8.50
31.11
u/l
—
6
9
8
18
4.57
2.82
1.8
2.1
—
—
—
0
0
8
18
4.57
2.82
1.8
2.1
—
—
—
0
0
8
18
4.57
2.82
1.8
2.1
—
—
—
0
0
5
6
8.49
2.76
2.0
3.0
—
—
—
0
0
5
6
8.49
2.76
2.0
3.0
—
—
—
0
0
5
6
8.49
2.76
2.0
3.0
—
—
—
0
0
194
1753
2.05
2.66
6.8
5.5
2.05
2.00
mu/l
0.20
186
1582
7
15
4.78
2.62
6.9
4.2
2.43
1.00
%
—
7
15
6
11
5.57
2.56
1.2
1.3
—
—
—
0
0
6
11
5.57
2.56
1.2
1.3
—
—
—
0
0
59
404
1.63
2.51
3.5
4.1
183.98
246.10
ng/l
0.23
50
334
7
16
4.48
2.49
1.0
1.1
—
—
—
0
0
7
16
4.48
2.49
1.7
2.5
—
—
—
0
0
7
17
4.22
2.38
1.1
1.2
104.86
100.47
pmol/l
—
7
17
15
65
2.41
2.37
1.7
1.5
—
—
—
0
0
11
40
2.84
2.31
1.5
2.5
32.73
32.93
pg
0.08
11
40
65
465
1.57
2.29
1.5
1.4
0.51
1.54
u/ml
1.35
22
117
5
9
5.66
2.22
2.6
1.9
—
—
—
0
0
5
10
5.09
2.08
1.4
1.0
—
—
—
0
0
5
10
5.09
2.08
9.2
7.9
—
—
—
0
0
38
245
1.67
2.02
2.7
3.9
5.18
7.05
umol/l
1.05
33
218
39
258
1.62
1.88
6.1
5.0
32.41
32.49
%
0.02
34
162
12
53
2.34
1.84
1.7
1.6
—
—
—
0
0
82
643
1.44
1.80
4.8
5.8
2.42
2.48
ug/l
0.03
71
570
5
13
3.91
1.72
1.0
1.0
—
—
—
0
0
28
175
1.69
1.68
1.6
1.4
—
—
—
0
0
5
14
3.63
1.62
1.6
1.1
—
—
—
0
0
5
14
3.63
1.62
1.6
1.1
—
—
—
0
0
24
147
1.71
1.55
8.6
9.2
23.89
24.92
mmol/l
0.80
24
142
6
22
2.77
1.44
1.5
1.2
367.17
333.74
u/l
—
6
22
5
17
2.98
1.36
1.2
1.4
—
—
—
0
0
33
231
1.51
1.27
14.6
7.8
—
—
—
0
0
41
302
1.44
1.23
1.8
1.6
—
—
—
0
0
169
1558
1.39
1.18
61.8
23.1
14.30
13.77
%
4.92
169
1547
56
440
1.37
1.17
14.0
4.1
1.02
1.02
kg/l
0.37
46
293
35
255
1.44
1.12
2.4
5.0
2.75
22.33
ug/l
0.64
27
215
19
123
1.60
1.03
14.5
3.5
1.01
1.02
ratio
2.06
19
117
12
70
1.76
0.94
1.2
1.2
—
—
—
0
0
12
71
1.73
0.91
1.3
1.2
—
—
—
0
0
8
47
1.73
0.81
8.5
1.2
0.91
0.82
nmol/l
—
8
39
8
48
1.69
0.79
2.0
1.1
3.44
4.13
mmol/l
—
8
43
7
38
1.87
0.74
1.7
1.4
—
—
—
0
0
60
508
1.25
0.73
3.4
4.8
26.11
22.56
%
0.83
31
257
7
41
1.73
0.70
1.0
1.1
16.39
23.62
u/l
—
7
32
5
27
1.87
0.69
1.6
1.5
—
—
—
0
0
7
43
1.65
0.67
1.1
1.6
—
—
—
0
0
189
1831
1.26
0.48
9.0
5.4
5.86
6.01
mmol/l
0.83
180
1672
13
95
1.39
0.45
1.3
1.3
—
—
—
0
0
5
33
1.53
0.41
11.8
2.7
1.18
1.20
mmol/l
—
5
33
5
33
1.53
0.41
11.8
2.7
107.60
106.18
mmol/l
—
5
33
0
16
0.00
0.41
0.0
1.5
—
0.90
—
0
8
0
16
0.00
0.41
0.0
1.5
—
0.95
—
0
8
0
16
0.00
0.41
0.0
1.5
—
1.19
—
0
8
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.7
—
49.21
—
0
14
44
395
1.14
0.29
2.7
3.4
0.72
0.81
ug/l
0.52
37
263
14
115
1.23
0.24
1.7
1.3
142.19
167.38
u/ml
—
9
44
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
6
52
1.16
0.19
1.2
1.6
—
—
—
0
0
15
162
0.92
0.06
4.2
3.5
561.73
184.84
ng/l
0.62
15
148
14
131
1.07
0.03
2.6
2.0
—
—
—
0
0
10
108
0.92
0.03
1.3
1.0
—
—
—
0
0
27
261
1.04
0.02
1.6
1.4
—
—
—
0
0
12
122
0.98
0.00
2.9
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
7.74
—
0
5
0
5
0.00
-0.00
0.0
3.6
—
0.07
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
8.14
—
0
7
0
9
0.00
-0.00
0.0
2.2
—
61.56
—
0
9
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.26
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint M13_MICROPOLYANG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_MICROPOLYANG | 2.749 [1.87, 4.04] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.51 |
During the follow-up period (1.1.1998 — 31.12.2019), 83 out of 398 females with M13_MICROPOLYANG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_MICROPOLYANG | 2.227 [1.42, 3.48] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.08 |
During the follow-up period (1.1.1998 — 31.12.2019), 83 out of 278 males with M13_MICROPOLYANG died.
Mortality risk
Mortality risk for people of age
years, who have M13_MICROPOLYANG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.3% | 0.427% |
| 5 | 1.814% | 2.869% |
| 10 | 4.159% | 6.919% |
| 15 | 8.407% | 12.425% |
| 20 | 14.379% | 21.206% |
Relationships between endpoints
↥Index endpoint: M13_MICROPOLYANG – Microscopic polyangiitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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